7 results about "Acute cerebral infarction" patented technology

The invention discloses a micro-catheter control method for an acute cerebral infarction interventional thrombectomy, which comprises the following steps: a micro-catheter control system acquires current position state information of a micro-catheter, and drives the micro-catheter to move to a target position according to preset parameters; three-dimensional position coordinates of the microcatheter are obtained in real time through an information acquisition module; the signal processing unit compares the actual position of the microcatheter with a preset target position in real time, judges whether the microcatheter reaches the preset position or not, and receives manually input adjustment parameters when it is monitored that the resistance exceeds a threshold value or the position deviates from a path; and the signal processing unit regenerates a control instruction based on the updated parameters, and drives the microcatheter to continuously move according to the corrected parameter constraint. By acquiring the illness state and blood vessel anatomical structure information of a patient, setting the parameters such as the target position and the moving path of the microcatheter and combining the three-dimensional position coordinate information acquired by the position sensor, the microcatheter can be accurately controlled to reach the target position and move according to the preset path.

The present invention relates to the technical field of cell therapy. Specifically disclosed are a mesenchymal stromal cell-based drug and a use thereof in the treatment of acute cerebral infarction. The present invention provides a cell-based drug, comprising mesenchymal stromal cells and a pharmaceutically acceptable excipient. Compared with stem cells, the mesenchymal stromal cells have a negative expression level of mRNA encoding self-renewal and differentiation in the mesenchymal stromal cells. The mesenchymal stromal cells account for 90% or more of the cell-based drug. The cell-based drug exhibits the characteristics and mechanism of action of stromal cells, homes to the neovasculature formed by endothelial cells at the injury site within an effective time window, plays a role in promoting / maintaining the neovasculature and remodeling the microenvironment of the injury site, fully ensures the safety and effectiveness of disease treatment, and provides a novel method for the diagnosis and treatment of related diseases.

This invention belongs to the field of medical device technology, specifically a carotid artery bypass catheter with a distal embolization protector. Addressing the problems of high risk of cerebral infarction due to plaque detachment during existing carotid endarterectomy procedures, as well as the cumbersome nature of current composite surgical procedures and reliance on specialized operating room conditions, this invention proposes the following solution: It includes a bypass catheter body and a distal embolization protection mechanism, connected together; it also includes a proximal end and a distal end. By integrating blood bypass and distal embolization protection functions into one unit, this invention allows surgeons to perform the procedure independently in a regular operating room without relying on a composite operating room. While establishing intraoperative blood bypass, it effectively intercepts potentially detached plaques or thrombi, significantly reducing the risk of postoperative acute cerebral infarction, decreasing disability and mortality rates, and simplifying the surgical procedure while shortening anesthesia and surgical time.

The application discloses a kind of acute cerebral infarction thrombolysis hemorrhage patient treatment combined cold deposit intervention device, it is related to cold deposit infusion technical field, including base, cross transfer box is rotatably connected on base;It also includes infusion hard pipe, infusion hose, fixed plate, first spring, limit frame, drive assembly and fixing mechanism, the end of infusion hose with needle is placed on placement table, infusion hard pipe lower portion is connected with fixed plate, first spring is connected between fixed plate and support, first spring is wound on infusion hard pipe, infusion hard pipe upper portion is connected with limit frame, cross transfer box lower portion is provided with drive assembly, cross transfer box is equipped with the fixing mechanism for clamping and fixing blood bag.The application is first by fixed mechanism to blood bag clamping and fixing, then by drive assembly, realize blood bag automatic replacement, avoid when infusion medical staff cannot leave sickbed, cause medical staff waste, improve the operation convenience of device.

This invention belongs to the field of medical data processing technology, specifically a method for constructing an intelligent prediction model for symptomatic hemorrhage transformation in acute ischemic stroke. The method includes step one: data acquisition and preprocessing: collecting clinical and imaging data of patients with acute ischemic stroke; the clinical data includes gender and the time from onset to intravenous thrombolysis; the imaging data includes the relative apparent diffusion coefficient value. This method for constructing an intelligent prediction model for symptomatic hemorrhage transformation in acute ischemic stroke, through setting a prediction model construction method, provides high visualization of the prediction of symptomatic hemorrhage transformation in acute ischemic stroke, and is convenient for clinical application. It utilizes a large language model to generate an interactive web interface, automatically generating native HTML code based on the prediction equation. The web interface includes an input module (receiving gender, DNT, and rADC values), a calculation module (calculating the probability value P in real time based on the equation), and a visualization module (displaying the results in a graphical form); further, the graphical form is limited to a bar chart.

The present disclosure may include a communication module configured to perform communication with an imaging device that captures an image of an acute cerebral infarction patient; and a processor configured to control an operation related to prediction of the occurrence time of acute cerebral infarction, wherein the processor is configured to: receive the image of the acute cerebral infarction patient from the imaging device through the communication module, classify the image into a first image corresponding to a liquid attenuation inversion recovery image and a second image corresponding to a diffusion-weighted image, acquire the first image and the second image, align the first image and the second image with respect to an MNI region corresponding to an activated region of a brain, detect an infarction region in the second image, and output a probability prediction value for the occurrence time of acute cerebral infarction based on the first image, the second image, and the infarction region.

The application belongs to the technical field of medicine, and particularly relates to application of trifluperidol in treatment of cerebrovascular diseases. Trifluperidol is a D1 / D2 dopamine receptor antagonist with oral activity and a novel PI3K inhibitor, and trifluperidol has anti-proliferative activity on cancer cells and induces apoptosis. The application discloses trifluperidol for the first time, and no report is found on effective treatment of trifluperidol against ischemic stroke, especially the application creatively proposes that trifluperidol significantly reduces the volume of acute cerebral infarction of a mouse with focal cerebral ischemia, which indicates that trifluperidol can be used for treating ischemic stroke.