45 results about "Coptis" patented technology

This invention discloses a muscle-relaxing and meridian-clearing health powder and its preparation and application methods, belonging to the technical field of traditional Chinese medicine external health care products. The health powder is composed of fifteen raw medicinal materials: safflower, angelica, asarum, kudzu root, red peony root, scutellaria, dragon's blood, saposhnikovia root, frankincense, myrrh, cinnamon twig, mugwort leaf, coptis root, *Lycopodium clavatum*, and *Clematis armandii*. These materials are dried, pulverized to 80-120 mesh, and then evenly mixed. This invention, through a unique formulation design, integrates multiple effects such as promoting blood circulation and removing blood stasis, dispelling wind and cold, relieving muscle tension and clearing meridians, and clearing heat and drying dampness. Combined with a refined pulverization process, it significantly improves the dissolution rate and transdermal absorption efficiency of the drugs. During use, a hot compress applied via steam allows the medicinal properties to directly reach the affected area, effectively relieving pain and discomfort in the neck, shoulders, waist, legs, and joints. This invention's product has a scientific formulation, advanced technology, is convenient to use, and highly safe, possessing broad market application prospects.

The invention relates to a pharmaceutical composition, which is prepared from adapalene, benzoyl peroxide, a traditional Chinese medicine extract, an acrylamide and acryloyl dimethyl sodium taurate copolymer, a mixture of isohexadecane and polysorbate 80, docusate sodium, EDTA (Ethylene Diamine Tetraacetic Acid) disodium, glycerol, poloxamer 124, propylene glycol and water, the traditional Chinese medicine extract comprises moutan bark, salvia miltiorrhiza, radix rehmanniae recen, radix sophorae flavescentis, coptis chinensis, rheum officinale, scutellaria baicalensis, menthol and borneol. According to the pharmaceutical composition disclosed by the invention, the synergistic antibacterial and anti-keratosis curative effects of adapalene and benzoyl peroxide can be maintained, and meanwhile, the occurrence rate of local skin dryness, erythema, desquamation, burning heat sensation and contact dermatitis can be remarkably reduced.

The present application relates to a kind of traditional Chinese medicine for treating female HPV infection, which is prepared from the following weight ratio of traditional Chinese medicine raw materials: 2-4 parts of catechu, 2-4 parts of half lotus, 2-4 parts of snakeberry, 1-2 parts of longjin, 1-2 parts of gotu kola, 1-2 parts of wintergreen, 1-2 parts of coptis, and 1-2 parts of sophora. The present application can effectively treat female HPV infection.

The application discloses a kind of solid teeth pain-relieving and inflammation-clearing traditional Chinese medicine composition, it is related to traditional Chinese medicine product technical field.The composition is composed of gypsum, raw rehmannia, coptis, talc, ocher, radix cyathulae and salvia miltiorrhiza seven raw medicinal materials, wherein gypsum, raw rehmannia are monarch drug, clear and purge stomach fire, cool blood and nourish yin;Coptis, talc are ministerial drug, clear heat and dry dampness, lead heat down;Ocher, radix cyathulae are auxiliary drug, heavy town counteract, lead fire down;Salvia miltiorrhiza is servant drug, promote blood circulation and remove blood stasis, promote tissue repair.Modern pharmacological research shows that each drug of the present party has the effects of anti-inflammatory, analgesic, antibacterial, improving microcirculation and protecting periodontal tissue etc.Clinical observation shows that the pain of most patients caused by stomach fire attacking upward, gum redness and swelling, burning pain, bleeding is significantly reduced after taking 1-2 doses, redness and swelling gradually subside.Compared with existing Chinese patent medicines, the present application is simple in prescription, low in cost, has the dual effects of rapid pain relief and long-term tooth fixation, and is especially suitable for patients with recurrent toothache and early periodontitis.

The application belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating abdominal distension and diarrhea of cold-heat complex type and a preparation method thereof. The technical scheme points of the traditional Chinese medicine composition are as follows: the traditional Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 3-6 parts of perilla, 3-10 parts of dried ginger, 3-12 parts of eucommia, 3-10 parts of scrophularia, 2-6 parts of coptis, 10-20 parts of fried coix seed, 6-10 parts of clear pinellia, 3-10 parts of dried tangerine or orange peel, 10-15 parts of poria, 6-10 parts of wheat-cooked atractylodes, 6-10 parts of vinegar-cured corydalis, 6-10 parts of vinegar-cured bupleurum, 6-10 parts of pericarpium zephyritae, 6-10 parts of chuanxiong, 6-10 parts of magnolia officinalis, 6-10 parts of fried hawthorn fruit, 3-6 parts of platycodon, and 3-10 parts of fried licorice. The traditional Chinese medicine composition and the traditional Chinese medicine water pill prepared from the traditional Chinese medicine composition have the effect of treating abdominal distension and diarrhea of cold-heat complex type.

The invention provides an application of combined use of xanthan gum, soya bean lecithin and a bitter agent in a bitter placebo matrix used in a traditional Chinese medicine decoction. The invention provides a placebo matrix composition capable of simulating the aftertaste of a traditional Chinese medicine decoction. The decoction comprises the following raw materials in percentage by weight: 0.03-0.04% of a bitterness agent, 0.05-0.2% of xanthan gum and 1.5-3% of soybean lecithin. The invention further provides the modified rheum officinale and coptis chinensis gargle placebo. Aiming at the defects that only instantaneous bitter taste can be generated by simply adding a bitterness agent and the bitter taste fades quickly in the prior art, the invention provides a method capable of actively regulating and remarkably prolonging the bitter taste sensing duration, so that the placebo can realistically reproduce a complete time-intensity curve of'bitter taste in mouth-lasting bitter taste after mouth 'of a traditional Chinese medicine decoction; therefore, the testee is prevented from being broken by bitterness lasting time difference. The method breaks through the limitation of traditional solution simulation, and aims to provide a new thought for preparation of traditional Chinese medicine placebo, further improve the sensory simulation level of the placebo and provide a method and reference for research of similar placebo.

The application discloses a compound Chinese herbal medicine fermentation preparation for preventing and treating hepatotoxicity of Penaeus vannamei and a preparation method thereof. Spore bacillus is used as a fermentation strain to perform aerobic fermentation on four traditional Chinese herbal medicine stem and leaf wastes, i.e. Astragalus stem and leaf, Rhubarb stem and leaf, Codonopsis stem and leaf and Coptis stem and leaf, so as to obtain a compound Chinese herbal medicine fermentation product with higher active substances. The compound Chinese herbal medicine fermentation preparation of the application can be added into the feed of Penaeus vannamei, so as to effectively prevent and treat hepatotoxicity of Penaeus vannamei.

The invention provides a traditional Chinese medicine extract with a folliculitis treatment effect, a preparation method of the traditional Chinese medicine extract and prepared bacteriostatic shampoo, and belongs to the technical field of daily necessities. The traditional Chinese medicine extract is prepared from the following raw materials in parts by mass: 5 to 20 parts of rhizoma coptidis, 5 to 20 parts of cortex phellodendri, 5 to 20 parts of radix scutellariae, 5 to 20 parts of vinegar frankincense, 5 to 20 parts of vinegar myrrh, 5 to 20 parts of radix et rhizoma rhei, 5 to 20 parts of rhizoma polygoni cuspidati, 5 to 20 parts of radix stemonae and 5 to 20 parts of herba taraxaci. By optimizing the compatibility and extraction process of a traditional Chinese medicine formula and combining the modern preparation technology, the invention aims to provide a traditional Chinese medicine hair washing therapeutic agent which is efficient in permeation, long-acting in bacteriostasis, safe, mild and strong in cleaning power, so as to overcome the defects of current chemical hair washing products in the field of folliculitis treatment.

This invention provides a composition comprising: 5-15 parts by weight of dried plum, 10-20 parts by weight of cinnamon twig, 10-20 parts by weight of ginseng, 3-8 parts by weight of angelica root, 5-15 parts by weight of asarum, 10-30 parts by weight of dried ginger, 5-15 parts by weight of Sichuan pepper, 5-15 parts by weight of phellodendron bark, 3-8 parts by weight of coptis root, 20-40 parts by weight of bitter wine, 20-30 parts by weight of japonica rice, 10-20 parts by weight of honey, 3-8 parts by weight of lily bulb, 40-60 parts by weight of polygonum multiflorum stem, 40-60 parts by weight of monkey head mushroom, 3-8 parts by weight of polygala root, and 5-15 parts by weight of poria cocos (a traditional Chinese medicine composition). Further, the composition comprises: 20-40 parts by weight of hydrolyzed milk protein, 20-40 parts by weight of fish collagen peptide, and 20-40 parts by weight of soybean peptide (a biological product). This invention also provides pharmaceutical preparations (especially pills) comprising the above composition, biological products, and methods for preparing the same. The composition has a significant effect on improving sleep and has broad application prospects.

The present invention relates to a composition for enhancing immunity, containing Cheongwi-san as an active ingredient. The Cheongwi-san of the present invention is a mixed herbal medicine extract consisting of Cimicifuga heracleifolia, Moutan Radicis Cortex, Angelica gigas, Coptis Rhizome, and fresh root of Rehmannia glutinosa. The Cheongwi-san of the present invention has excellent effects of increasing the activity of NK cells, increasing the production amounts of IFN-γ and TNF-α, and reducing the survival rate of cancer cells, and has the effect of inhibiting influenza virus infection, and thus can be effectively used as a health functional food for enhancing immunity, a feed additive for animals for enhancing immunity, or a pharmaceutical product for preventing and treating diseases caused by decreased immunity.

The invention discloses a compound traditional Chinese medicinal material feed additive for stress conditioning of calves as well as preparation and application of the compound traditional Chinese medicinal material feed additive. Comprising the following raw materials: 1-3 parts of schizonepeta, 1-3 parts of cassia twig, 3-9 parts of ephedra, 2-6 parts of coptis chinensis, 1-3 parts of scutellaria baicalensis, 3-9 parts of cape jasmine, 1-3 parts of poria cocos, 5-15 parts of astragalus membranaceus, 1-3 parts of bighead atractylodes rhizome, 5-15 parts of platycodon grandiflorum, 5-15 parts of radix stemonae, 3-9 parts of white mulberry root-bark, 3-9 parts of hawthorn, 3-9 parts of massa medicata fermentata fujianensis, 5-15 parts of malt, 4-12 parts of radix bupleuri, 3-9 parts of mangnolia officinalis, 2-6 parts of semen lepidii, 1-3 parts of fructus forsythiae, 3-9 parts of ligusticum wallichii, 1-3 parts of houttuynia cordata Through the synergistic effect of multiple traditional Chinese medicines, the stress of the calves can be relieved from multiple dimensions of resisting viruses, regulating intestinal flora, enhancing immunity and the like.

The invention relates to the technical field of life cultivation and health preservation, and discloses a life cultivation particle which is prepared from the following raw materials in parts by weight: 1-5 parts of ginseng, 1-5 parts of pseudo-ginseng, 1-5 parts of coptis chinensis, 15-25 parts of lotus root, 5-15 parts of Chinese mahonia, 5-15 parts of liquorice, 1-5 parts of American ginseng, 1-3 parts of cinnamon, 2-6 parts of blood pseudo-ginseng, 5-15 parts of salvia miltiorrhiza, 1-5 parts of paris polyphylla, 5-15 parts of ligusticum wallichii and 1-5 parts of gastrodia elata. The health-preserving particle breaks through the limitation of single target spot of the existing product, realizes multi-dimensional comprehensive conditioning, and accurately solves the problem of compound sub-health. All the raw materials have a synergistic effect and have the functions of coordinating intestines and stomach, invigorating qi and blood, soothing the nerves, helping sleep and warming and invigorating kidney yang, and a virtuous circle is formed. The traditional Chinese medicine is balanced in cold and warm, mild and safe, and avoids the defect that the stomach is damaged by greasy taste or cold and cool yang is damaged. The raw material medicines are edible or common traditional Chinese medicinal materials, are scientific in proportioning, have synergistic effects, are suitable for a wide range of people, and meet diversified health-preserving requirements of modern people.

The application discloses a kind of resistance identification and system breeding method of excellent strain of anti-root rot Coptis, it is related to the technical field of medicinal plant disease resistance identification and strain breeding, the application is first according to pathogen composition, inoculation body preparation, seedling age, substrate treatment and environment window formation comparable batch group in seedling inoculation stage, resistance observation record generation group calibration processing result is introduced into the same batch of Coptis control strain, only allow comparable batch group to enter group screening in group calibration processing result is effective state. In this way, the resistance observation record that enters the same comparison chain meets the two prerequisites of consistent inoculation condition and batch response effective simultaneously, batches of inoculation failure, inoculation too strong, control loss or control deviation anomaly no longer directly enter group retention set, so that the disease level source of Coptis candidate strain is constrained to the same inoculation pressure and the same observation prerequisite, solve the problem that the disease level source of batches is inconsistent in front and back batches in multiple batches screening is directly combined and tabled.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to an external traditional Chinese medicine composition for resisting HPV infection as well as a preparation method, a component analysis method and application thereof. The external traditional Chinese medicine composition is prepared from the following raw materials: rhizoma atractylodis, cortex phellodendri, radix sophorae flavescentis, rhizoma coptidis, rhizoma polygoni cuspidati, herba taraxaci, humifuse euphorbia herb, herba selaginellae, semen juglandis and fructus cnidii, all the medicines are used together, both symptoms and root causes are taken into consideration, middle-jiao can be healthy to prevent endogenesis of damp evil, lower-jiao can be cleared to remove damp-heat and excess syndromes, and the external traditional Chinese medicine composition has the effects of detoxifying and resisting viruses and conforms to the pathogenesis characteristics of HPV infection. The external traditional Chinese medicine composition can directly act on a lesion part through a mucous membrane drug delivery system by being directly applied to an affected part, the treatment effect is remarkable, and gastrointestinal discomfort caused by oral medicine can be reduced.

The invention relates to a traditional Chinese medicine composition for treating blurred vision and muscae volitantes and a preparation method thereof. The invention belongs to the technical field of traditional Chinese medicines, and is helpful for relieving symptoms such as blurred vision and muscae volitantes. The formula comprises the following components: fructus lycii, flos chrysanthemi, herba taraxaci, radix ophiopogonis, pericarpium citri reticulatae fried with honey and bran, cortex fraxini, semen cuscutae, dendrobium officinale, soft talc, rhizoma coptidis, radix cynanchi paniculati, radix scutellariae, fried semen cassiae, fried fructus viticis, radix rehmanniae praeparata, prepared fructus corni, cortex moutan, rhizoma dioscoreae with honey and bran, white poria, rhizoma alismatis and bear gall, wherein the fructus lycii, the flos chrysanthemi, the herba taraxaci, the cortex fraxini, the semen cuscutae and the fried fructus viticis have the effects of clearing away heat and toxic materials, nourishing the liver and improving eyesight and the like; through the combined effect of various herbal medicine components, compared with similar products, the effect is better, and compared with western medicines, the Chinese herbal medicines reduce the potential safety hazard of medicine taking. The traditional Chinese medicine composition has the remarkable effects of clearing away heat and toxic materials, nourishing the liver, improving eyesight and relieving eye fatigue and blurred vision, muscae volitantes and other symptoms caused by overuse of eyes, and is safe and effective after being taken for a long time.

This invention discloses a compound traditional Chinese medicine detoxifying ointment and its preparation method. The compound traditional Chinese medicine detoxifying ointment comprises a traditional Chinese medicine extract, triclosan, a gel matrix, a cooling and antipruritic agent, a moisturizer, a surfactant, a pH adjuster, and purified water. The traditional Chinese medicine extract is prepared by a group extraction process using five medicinal slices—honeysuckle, scutellaria, coptis, rhubarb, and corydalis—in a specific ratio: honeysuckle, scutellaria, and corydalis form the first group, while coptis and rhubarb form the second group. These are extracted separately by ethanol reflux extraction and microfiltration purification, then a colloidal dispersion system is formed using a pH segmented control method, followed by concentrating the extracts. This invention, through the synergistic combination of the traditional Chinese medicine extract, low-concentration triclosan, and the cooling and antipruritic agent, enables the product to possess multiple effects, including highly effective broad-spectrum antibacterial properties, cooling and antipruritic effects, and blood-activating and analgesic effects. Furthermore, it is non-irritating to the skin, exhibits good stability, and is suitable for industrial production.

The application discloses an alternating shovel-digging type coptis harvest machine, which comprises a shovel-digging device, and the shovel-digging device is a four-bar linkage mechanism and specifically comprises a crankshaft, a shovel-digging connecting rod, a shovel-digging rocker and a tooth harrow. A point A is taken as the coordinate origin of the rotation center of the crankshaft, and a Cartesian coordinate system is established. A connecting point D of the shovel-digging rocker and a machine frame is a fixed point. A hinged point of the upper end of the shovel-digging connecting rod is a point B. A hinged point of the lower end of the shovel-digging connecting rod is a point C. The motion trajectory equation of the tooth harrow for shoveling and digging coptis is: wherein l1 is the length between the points A and B, l2 is the length between the points B and C, and l3 is the length between the points C and D. The included angle between the AB connecting line and the positive direction of the X axis is θ1. The included angle between the shovel-digging connecting rod BC and the positive direction of the X axis is θ2. The application solves the technical problem of developing an alternating shovel-digging type coptis harvest machine which can complete the cutting, shoveling, lifting and collecting operations of coptis on a slope in one time and can improve the shoveling efficiency.

The invention discloses a Wanchu capsule preparation method capable of reducing harmful impurities and improving overall stability, and belongs to the technical field of traditional Chinese medicine preparations, the Wanchu capsule preparation method comprises the following steps: S1, mixing rhizoma picrorhizae, rhizoma coptidis, catechu and fragrant ink according to a formula ratio, crushing into fine powder to form a mixture I, adding powdered sugar into the mixture I, and uniformly stirring and mixing to form a mixture II; mixing and grinding borneol and artificial musk to form a mixture III; s2, boiling the ox bile for 10-30 minutes, and filtering to obtain filtrate; s3, adding an adjusting stabilizer into the filtrate, wherein the adding amount of the adjusting stabilizer is that the pH value of the filtrate is adjusted to 7.2-7.8; s4, adding the formula amount of bear gall powder and calculus bovis into the filtrate adjusted in S3 to form a mixture IV; s5, adding the mixture II into the mixture IV to form a mixture V, then adding an ethanol water solution, and performing granulation, drying, granule finishing and screening through a granulator to obtain intermediate granules; and S6, uniformly mixing the mixture III with the intermediate particles, sub-packaging, and filling into capsules to prepare the Wanchu capsules. Harmful impurities are reduced, and the overall stability is improved.

The application belongs to the technical field of data prediction, and discloses a traditional Chinese medicine extraction process intelligent optimization system and method; including, performing M times of scanning collection on new batch of Coptis rhizome root powder to form a multi-modal feature vector; defining a hierarchical rule database including a static rule library and a dynamic rule library, and adaptively adjusting the weight of each rule; the dynamic rule library is generated based on a data pool, the features of the data pool are compared, simulated and judged to generate new rules; whether there is a conflict between the rules is judged based on conflict simulation checking, and the severity of the conflict is judged, and for serious conflicts, a hierarchical arbitration mechanism is used for conflict resolution; the multi-modal feature vector of the new batch of Coptis rhizome root powder is output to the hierarchical rule database, the optimal process parameter set is obtained, and is issued to the extraction equipment for execution, so that the traditional Chinese medicine extraction process intelligent optimization is realized.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for improving diabetes mellitus complicated with ejection fraction retention type heart failure, a pharmaceutical preparation, a preparation method and application. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 5-15 parts of ginseng, 10-30 parts of astragalus membranaceus, 5-15 parts of coptis chinensis, 5-15 parts of polygonum cuspidatum, 10-30 parts of radix puerariae and 20-40 parts of caulis spatholobi. After the traditional Chinese medicine composition is used for treating mice, FBG and body weight of the mice are not obviously changed, but the insulin sensitivity can be increased, the high glucose state of cardiac metabolism can be improved, the diastolic dysfunction of DM-HFpEF mice can be relieved, meanwhile, the traditional Chinese medicine composition can relieve cardiac microvascular fibrosis by influencing the EndMT process, and the curative effect is good. The invention further illustrates that the traditional Chinese medicine composition mediates cell autophagy to intervene in'cell failure-EndMT 'to improve the potential action mechanism of cardiac fibrosis.

The present application relates to the field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating diabetic foot and a preparation method thereof.The traditional Chinese medicine composition is made of the following weight parts of traditional Chinese medicine raw materials: 180-220 parts of raw astragalus, 140-160 parts of angelica, 90-120 parts of dogwood, 180-220 parts of coptis, 180-220 parts of scrophulariaceae, 90-120 parts of atractylodes, 90-120 parts of cortex phellodendri, 40-60 parts of white yam, 40-60 parts of pearl powder, 40-60 parts of geum japonicum and 4-8 parts of artificial musk.The traditional Chinese medicine composition has the effects of benefiting qi and nourishing blood, nourishing yin and purging fire, clearing heat and drying dampness, promoting blood circulation and generating muscle, and has a good therapeutic effect on foot ulcer caused by diabetes.Moreover, the traditional Chinese medicine composition is safe and effective for long-term use, and the patient is not prone to recurrence.

The invention discloses an anti-atherosclerosis pharmaceutical composition as well as a preparation method and application thereof, and relates to the technical field of medicines. The pharmaceutical composition is composed of a traditional Chinese medicine extract and a small molecule active component in a weight ratio of (50-70): (1-8), the traditional Chinese medicine extract is prepared from the following medicinal raw materials in parts by weight: 10 to 30 parts of red yeast rice, 15 to 40 parts of radix salviae miltiorrhizae, 10 to 25 parts of rhizoma chuanxiong, 5 to 15 parts of rhizoma coptidis and 20 to 50 parts of radix astragali seu hedysari; the small molecular active component is composed of sulforaphene and cucurbituril according to a mass ratio of (1-5): (0.03-0.12). The pharmaceutical composition developed by the invention has a remarkable improvement effect on atherosclerosis symptoms.

The invention belongs to the technical field of candida albicans treatment medicines, and particularly relates to a novel application of coptis chinensis polysaccharide in preparation of medicines for preventing and treating candida albicans infectious diseases. In a Candida albicans infected oropharyngeal candidiasis mouse model for the first time, it is found that after 50 mg / kg and 100 mg / kg of coptis polysaccharide are used for treatment for four days, the fungal loading capacity and inflammatory response in mouse tongue tissue are reduced, and the cure rate of mice is increased. It is shown that the coptis chinensis polysaccharide has a treatment effect on the oropharyngeal candidiasis, infected by candida albicans, of mice. Compared with antibiotic drugs, the coptis polysaccharide is an effective component of traditional Chinese medicine coptis, is not easy to generate drug resistance, has small toxic and side effects, is low in price, and has a treatment effect on mice with oropharyngeal candidiasis, so that the coptis polysaccharide can replace the antibiotic drugs and becomes a new drug for treating oropharyngeal candidiasis.

The invention belongs to the technical field of traditional Chinese medicines, and discloses an application of coptis chinensis paste in preparation of a medicine for treating or preventing atopic dermatitis, and the coptis chinensis paste is used for treating the atopic dermatitis by repairing a skin barrier and regulating immune response. Pharmacodynamic verification proves that the rhizoma coptidis paste shows a good curative effect in the aspect of improving AD-like dermatitis symptoms, skin atrophy side effects similar to dexamethasone are not observed at a high dosage, and the rhizoma coptidis paste shows better treatment safety characteristics. According to the application disclosed by the invention, the action mechanism of the coptis chinensis cream for treating atopic dermatitis is defined, the coptis chinensis cream promotes synthesis of skin barrier structural protein to consolidate defense and effectively inhibits release of alarm elements such as TSLP / IL-33 to block inflammation initiation, finally, effector factors such as IL-4 / IL-13 and the like and IgE are reduced, inflammatory cell reactions such as mastocyte infiltration are relieved, and the curative effect of the coptis chinensis cream on atopic dermatitis is improved. Therefore, clinical symptoms and pathological changes of AD are improved.

The invention discloses a traditional Chinese medicine preparation for treating burns and scalds and a preparation and use method thereof, and belongs to the technical field of traditional Chinese medicine preparations for burns and scalds. The preparation comprises 27 medicines such as dragon's blood, garden burnet, golden cypress, coptis chinensis, beewax and aloe, and has the effects of resisting bacteria and diminishing inflammation, clearing away heat and toxic materials, relieving pain and preventing corrosion, promoting blood circulation to remove blood stasis, moistening skin and relieving itching. Through clinical trials for many years, the traditional Chinese medicine is obvious in effect and free of toxic and side effects, and promises that scars are not left on second-degree scalds. The use of the test preparation completely adapts to the awareness of people to the scald ointment, ensures that the basic risks of secondary damage and cross infection do not occur after scald treatment, fundamentally solves the negative effects caused by unreasonable use, and is affirmed by medical workers and experts. As a common necessary external ointment, the preparation plays a key role in the treatment process of emergency treatment, and the efficacy, the action, the medicinal components, the use method, the main application and the effect of the scald ointment are introduced in detail, so that a patient can better understand and use the product.

The application belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating sepsis cardiomyopathy and application thereof, which mainly comprises, by mass fraction, 10-50 parts of ginseng, 5-20 parts of rhubarb, 10-30 parts of monkshood, 5-20 parts of coptis, 5-30 parts of scutellaria and 5-20 parts of safflower. Clinical tests show that the traditional Chinese medicine composition can not only improve circulation and heart function of patients with sepsis yang deficiency and blood stasis syndrome, reduce inflammatory response and improve prognosis, and has good safety, but also can improve hypotension of patients with sepsis shock and deficiency of healthy qi and excess of evil qi, improve hemodynamics, tissue perfusion and blood coagulation function of patients with sepsis shock, and has no obvious influence on liver and kidney functions, and has good safety.

The invention discloses a mutant of coptis chinensis oxygen methyltransferase CcOMT1 as well as a preparation method and application of the mutant. The mutant is a mutant CcOMT1-M3 obtained by mutating serine at the 109th site of the coptis chinensis oxygen methyltransferase CcOMT1 into leucine, mutating cysteine at the 250th site of the coptis chinensis oxygen methyltransferase CcOMT1 into alanine and mutating leucine at the 300th site of the coptis chinensis oxygen methyltransferase CcOMT1 into alanine. According to the invention, the CcOMT1-M3 mutant is successfully constructed through mutation iteration, and the CcOMT1-M3 mutant can greatly improve the catalytic efficiency and the substrate conversion rate.

The present application relates to the technical field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition for treating stomach diseases, which is prepared from 23-25 grams of lily, 8-10 grams of magnolia officinalis, 8-10 grams of corydalis, 5-7 grams of melia toosendan, 5-7 grams of galangal, 8-10 grams of rhizoma cyperi, 23-25 grams of fried white peony root, 5-7 grams of licorice, 5-7 grams of coptis, 1-3 grams of evodia, 10-14 grams of salvia miltiorrhiza, 2-4 grams of sandalwood, and 5-7 grams of amomum villosum. The traditional Chinese medicine composition for treating stomach diseases is prepared by mixing the above-mentioned raw materials, adding 400 ml of water, boiling, and then continuing to decoct for 30 minutes, filtering the extracted medicinal liquid, adding 400 ml of water to the residue, boiling, and then continuing to decoct for 30 minutes, filtering the extracted medicinal liquid, and combining the two times of extracted medicinal liquid. The traditional Chinese medicine composition for treating stomach diseases is used for treating bile regurgitation gastritis of the type of liver depression and blood stasis, and has the effects of regulating cold and heat and regulating qi and blood.

This invention provides a burn medication composition and its preparation method, belonging to the field of traditional Chinese medicine preparation technology. The medication composition includes a powder and an ointment. The powder comprises the following components in parts by weight: 6-9 parts of puffball powder, 6-9 parts of cattail pollen charcoal powder, 1-2 parts of peony bark powder, 3-5 parts of peppermint powder, and 3-5 parts of saposhnikovia root powder. The ointment comprises the following components in parts by weight: 6-12 parts of gromwell root, 5-9 parts of coptis root, 5-9 parts of scutellaria root, and 5 parts of astragalus root. -9 parts, Phellodendron bark 5-9 parts, Gardenia fruit 5-9 parts, Sophora flavescens 5-9 parts, Ligusticum chuanxiong 5-9 parts, Zanthoxylum bungeanum 5-9 parts, Salvia miltiorrhiza 5-9 parts, Angelica sinensis 5-9 parts, Ginseng 5-9 parts, American ginseng 5-9 parts, Artemisia capillaris 5-9 parts, Artemisia argyi 5-9 parts, Indigo naturalis 5-9 parts, Pearl powder 2-5 parts, Borneol 2-5 parts, Rosin 5-9 parts, Beeswax 150-200 parts, High-proof liquor 20-50 parts, and Vegetable oil 900-1200 parts. This invention is effective and has significant therapeutic effects on burn wounds.

The present application relates to the field of traditional Chinese medicine, and provides a traditional Chinese medicine composition for treating chronic gastritis with cold and heat symptoms, which is prepared from the following traditional Chinese medicines in parts by weight: 20-45 parts of lily, 10-25 parts of Jiang Banxia, 10-25 parts of atractylodes, 10-25 parts of white peony root, 8-20 parts of codonopsis, 8-20 parts of Anemarrhena, 8-20 parts of areca nut, 8-20 parts of magnolia bark, 8-20 parts of jujube, 6-15 parts of scutellaria, 6-15 parts of dried ginger, 6-15 parts of licorice, 6-15 parts of fried licorice, 3-12 parts of sandalwood, and 1.5-6 parts of coptis. The present application is based on the theory of traditional Chinese medicine, and can regulate the whole body through multiple targets such as clearing heat and dampness, harmonizing stomach and descending adverse qi, promoting qi circulation and eliminating mass, and nourishing yin and strengthening the body resistance. The present application can promote blood circulation and qi circulation, unblock qi, and improve the overall health of patients with chronic gastritis. Moreover, the present application has few side effects and is suitable for long-term use.