The invention discloses a natural tooth cleaning mousse foam composition, which comprises: acerola cherry fruit powder, a green tea extract, a peony root extract, a panax notoginseng extract, an aloe extract, a peppermint extract, a honeysuckle extract, a rice husk extract, a lemon extract, a clove extract, a lotus extract, a Korean angelica sinensis extract, a zanthoxylum nitidum extract, a natural foaming agent, edible glycerol, erythritol, sodium alpha-glucan, xylitol, fructooligosaccharide, and water. According to the present invention, the product is foam-like, and the active ingredients can be rapidly and uniformly attached to the teeth and penetrate into the spaces between the teeth, such that the cleaning function can be effectively provided, and the functions of tooth decay prevention, tooth whitening, gingiva strengthening, tartar clearing and the like can be comprehensively provided.