158 results about "Carthamus" patented technology

The invention discloses an extraction method of safflower leaf exosome-like nano-vesicles and application of the safflower leaf exosome-like nano-vesicles in preparation of drugs for preventing and treating adriamycin-induced cardiotoxicity, fresh safflower leaves are taken and cleaned, a PBS solution is added for crushing and filtering, filtrate is collected and continuously centrifuged, supernate is taken and subjected to ultracentrifugation, precipitates are collected after centrifugation, and the safflower leaf exosome-like nano-vesicles are obtained; and filtering and sterilizing by using a filter membrane to obtain the safflower leaf exosome-like nano-vesicles. The carthamus tinctorius leaf exosome-like nano-vesicles can significantly improve the heart function of doxorubicin-induced cardiotoxic mice; myocardial injury induced by doxorubicin can be repaired, and myocardial fibrosis induced by doxorubicin can be inhibited; the content of a myocardial injury marker lactic dehydrogenase in body serum can be reduced, a new treatment strategy is provided for preventing and treating adriamycin-induced cardiotoxic diseases, and the application prospect is good.

The invention discloses glycosyltransferase in safflower and a related biological material and application thereof. The invention firstly discloses any one of the following proteins: A1) a protein consisting of an amino acid sequence as shown in a sequence 2; a2) a fusion protein obtained by connecting the N end or / and C end of the protein as shown in the sequence 2 with a protein tag. The invention further discloses the protein related biological material and application thereof. The HSYA biosynthesis key glycosyl transferase gene UGT708U5 is obtained from safflower for the first time, it is proved that the protein UGT708U5 coded by the gene can catalyze phloretin to form HSYA precursor compounds, namely phloretin-mono-C-glucoside and phloretin-di-C-glucoside, and the gene plays an important role in biosynthesis and heterologous production of HSYA; the method has important theoretical and practical significance for regulating and producing the quinonechalcone C-glycoside compounds of plants and cultivating high-quality safflower carthamus.

This invention relates to the field of traditional Chinese medicine (TCM) technology, specifically to a nasal massage oil, its preparation method, and its application. The nasal massage oil is prepared from the following TCM raw materials in the indicated weight proportions: 4-6 parts of roasted Xanthium sibiricum, 1.5-3.5 parts of Magnolia biondii, 1.5-3.5 parts of Angelica dahurica, 0.3-0.7 parts of Mentha haplocalyx, 0.8-1.2 parts of Borneol, 2-4 parts of Sinapis alba, 1-3 parts of Artemisia argyi, 1-3 parts of Carthamus tinctorius, 1-3 parts of Cinnamomum cassia, 2-4 parts of Pueraria lobata, and 80-120 parts of sesame oil as a base. This application, through scientific formulation and reasonable proportioning, effectively solves the technical problem that existing nasal massage mediums only provide lubrication and lack targeted TCM conditioning effects, failing to achieve synergistic effects between massage and medication. It achieves an integrated effect of "massage lubrication - drug penetration - TCM conditioning."

The invention provides a method for carrying out genetic transformation on safflower carthamus in a tissue-free culture mode, which comprises the following steps: cutting off radicles of newly germinated safflower carthamus seedlings, taking the radicles as explants, infecting the explants in a mode of smearing agrobacterium rhizogenes containing a target gene on wounds, burying the infected explants in soil for culturing, and carrying out tissue-free culture on the explants to obtain the safflower carthamus. The transgenic safflower hairy roots are obtained. The method fills the blank of a safflower non-tissue culture genetic transformation system, the whole transformation period is 20-30 days, and the method can be applied to rapid and efficient genetic transformation, gene editing and variety improvement of safflower.

The present invention provides a traditional Chinese medicine composition, a preparation method thereof and an application, belonging to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition of the present invention comprises raw materials in the following parts by weight: 3-5 parts of Atractylodes lancea, 3-5 parts of Gentiana macrophylla, 7-9 parts of Ligusticum chuanxiong, 10-14 parts of Carthamus tinctorius, 3-5 parts of Notopterygium incisum, 10-14 parts of Angelica sinensis, 10-14 parts of Cyathula officinalis, 3-5 parts of Cyperus rotundus, and 7-9 parts of Glycyrrhiza uralensis. Based on the situation of stasis in patients with arthralgia syndrome, the present invention performs drug compatibility for those with stasis in arthralgia syndrome, and has a significant therapeutic effect on arthralgia syndrome caused by wind, cold, dampness and stasis.

The invention relates to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine application for relieving neck-shoulder and lumbocrural pain and a preparation method thereof. The traditional Chinese medicine application is prepared from, by mass, 15-50 g of obscured homalomena rhizome, 15-50 g of cortex illicii, 15-50 g of herba lycopodii, 15-50 g of rhizoma curcumae longae, 15-50 g of rhizoma corydalis, 15-50 g of radix puerariae, 15-50 g of garden balsam stem, 15-50 g of radix saposhnikoviae, 15-50 g of flos carthami, 15-50 g of radix cyathulae, 15-50 g of rhizoma seu radix notopterygii, 15-50 g of radix angelicae pubescentis, 15-50 g of lumbricus, 15-20 g of frankincense, 15-20 g of myrrh and 20-30 g of radix clematidis. Compared with traditional medicine application with a single effect, the traditional Chinese medicine application has the advantages that the pain relieving effect is quicker, the symptom improvement is more thorough, meanwhile, the application range of treating the neck, shoulder, waist and leg pain is expanded, and a patient can operate the traditional Chinese medicine application at home without assistance of professional medical equipment.

The invention discloses a traditional Chinese medicine composition for treating chronic kidney diseases. The traditional Chinese medicine composition is prepared from the following raw materials: codonopsis pilosula, radix astragali preparata, prepared rehmannia root, moutan bark, peach kernel, safflower and oldenlandia diffusa. The traditional Chinese medicine composition has the effects of improving renal anemia, enhancing the immune function, effectively reducing kidney microthrombus, regulating the filtration state of the kidney and relieving the microinflammation state of a patient, and has no side effect. The traditional Chinese medicine composition has an excellent effect on patients with chronic kidney diseases, and can improve renal fibrosis and delay the progress of diseases. Through reasonable compatibility of the raw materials, the raw materials give full play to the unique performance and efficacy of the raw materials, and also give full play to the complementary effect of the raw materials, and the medicinal effects of the raw materials supplement each other, so that the kidney function is gradually recovered.

The invention discloses a traditional Chinese medicine composition for promoting hair growth and a preparation method thereof. The traditional Chinese medicine composition comprises an oral composition and an external lotion. The oral prescription comprises 11 traditional Chinese medicines in parts by weight: radix angelicae, poria cocos, amomum kravanh, polygonum multiflorum, safflower carthamus, angelica sinensis and the like, the polygonum multiflorum and mulberry are monarch drugs for nourishing liver and kidney, the angelica sinensis and the like are ministerial drugs for promoting blood circulation to remove blood stasis, the radix angelicae and the like are adjuvant drugs for dispelling wind and arresting itching, and the liquorice is a conductant drug for harmonizing the medicines; the external lotion is composed of Ligusticum wallichii, Gleditsia sinensis and speranskia tuberculata, the Ligusticum wallichii expands blood vessels and increases nutrition delivery, the Gleditsia sinensis cleans scalp and inhibits fat overflow and alopecia, and the orchid grass inhibits bacteria and diminishes inflammation. The composition comprehensively conditions the body and scalp environment through combination of oral administration and external use. Clinical tests show that after the traditional Chinese medicine composition is used for 3 months, the alopecia of more than 80% of subjects is reduced, the growth speed of new hair is averagely increased by 30%, the hair quality is improved, the safety is high, the adverse reaction is few, the effect is obviously superior to that of similar products, and a new effective choice is provided for promoting hair growth.

The invention discloses application of a yang-warming and cold-dispelling traditional Chinese medicine composition in preparation of a medicine for improving cold limbs, and belongs to the field of traditional Chinese medicines. The prescription consists of folium artemisiae argyi, cassia twig, ligusticum wallichii, notopterygium root, divaricate saposhnikovia root, ginger, pepper, safflower, radix clematidis, radix aconiti carmichaeli, dried ginger and cinnamon according to a specific mass part ratio. The prescription disclosed by the invention has the effects of warming channels and expelling cold, and promoting blood circulation to remove meridian obstruction, and is mainly used for improving the symptoms such as cold hands and feet, intolerance of cold and sensation of chill, joint crymodynia and the like caused by insufficiency of yang qi and congealing cold in meridians. The invention also provides a preparation method of dosage forms such as an application agent of the prescription. Clinical tests show that the prescription preparation, especially the acupoint application agent, can obviously improve the symptoms, the total effective rate can reach 93.3%, the safety is good, and a safe, effective and convenient-to-use external treatment choice is provided for related diseases.

The utility model discloses a parallel mechanical arm auxiliary leveling device on a safflower picking machine, and particularly relates to the technical field of safflower picking machines, the parallel mechanical arm auxiliary leveling device comprises a leveling device table, and an adjusting mechanism is arranged at the bottom of the leveling device table; the adjusting mechanism comprises a fixing shaft, the fixing shaft is fixedly installed at the bottom of the leveling device table, a rotating shaft is hinged to the bottom of the fixing shaft, and a balance aluminum frame is fixedly connected to the bottom of the rotating shaft. By arranging the adjusting mechanism and the air pressure control mechanism, air pressure in each air cylinder is adjusted, damage to petals and stalks caused by shaking or inclining of the mechanical arm is avoided, the picking precision and quality are greatly improved, damage to safflower carthamus caused by improper picking is reduced, the picking quality and economic benefits of safflower carthamus are improved, and the picking efficiency of safflower carthamus is improved. By flexibly adjusting the air pressure of each air cylinder, unbalance caused by inclination and unevenness of the terrain is compensated, so that the picking machine can stably work under various severe terrain conditions.

The present invention relates to a traditional Chinese medicine composition for treating stroke. The traditional Chinese medicine composition is prepared from 10 - 30 parts by weight of Poria cocos, 5 - 25 parts by weight of Uncaria rhynchophylla, 5 - 25 parts by weight of Salvia miltiorrhiza, 3 - 18 parts by weight of Citrus reticulata Blanco, 3 - 18 parts by weight of Gastrodia elata Blume, 3 - 18 parts by weight of Ligusticum chuanxiong Hort., 3 - 18 parts by weight of Pinellia ternata (Thunb.) Breit., 1 - 15 parts by weight of Arisaema cum Bile, and 1 - 15 parts by weight of Carthamus tinctorius L. The traditional Chinese medicine composition of the present invention resolves phlegm and extinguishes wind, promotes blood circulation and dredges collaterals, has high safety, and has remarkable curative effects on treating stroke, especially acute ischemic stroke.

The present application belongs to the technical field of dermatosis treatment products, and particularly relates to a soft pelleted medicine and a preparation method thereof. The soft pelleted medicine is prepared from the following raw materials in parts by weight: 20-40 parts of Ramulus cinnamomi, 25-35 parts of Radix astragali, 5-15 parts of Semen persicae, 5-15 parts of Ophiopogon, 5-15 parts of Carthamus tinctorius, 15-30 parts of calcined Radix paeoniae alba, 10-20 parts of Radix angelicae sinensis, 15-30 parts of Radix rehmanniae preparata, 20-40 parts of Radix codonopsis, 5-15 parts of Radix paeoniae alba, 5-10 parts of Ephedra, 5-10 parts of Radix rubiae, 5-15 parts of Centella asiatica, 2-5 parts of Radix et Rhizoma aconiti, 5-10 parts of Salvinia natans, and 5-10 parts of Rhizoma zingiberis. The soft pelleted medicine provided by the present application has the main effects of warming yang and benefiting qi, promoting blood circulation to remove meridian obstruction, dispelling cold and dampness, removing blood stasis and promoting tissue regeneration, and is used for treating dermatosis such as scleroderma, frostbite, Raynaud's disease, skin atrophy, and the like, and particularly has remarkable effects on scleroderma, frostbite, Raynaud's disease, and skin atrophy.

The invention belongs to the technical field of traditional Chinese medicine preparations, and provides an external tincture patch for treating lumbago in the traditional Chinese medicine internal medicine department and a preparation method, the tincture patch is composed of a solvent and effective components, and the effective components comprise 10-12 g of scalded rhizoma cibotii, 10-12 g of radix angelicae pubescentis, 10-12 g of salted eucommia ulmoides, 8-12 g of achyranthes bidentata, 6-10 g of safflower carthamus, 8-10 g of wine-processed ligusticum wallichii, 12-15 g of lycopodium clavatum, 12-15 g of impatiens balsamina, 6-9 g of frankincense, 6-9 g of myrrh and 3-5 g of natural borneol. The external tincture patch for the lumbago in the traditional Chinese medicine internal medicine department sequentially comprises a backing layer, a medical pressure-sensitive adhesive layer and an anti-seepage ring from bottom to top, an adsorption layer for soaking a tincture to a saturated state is arranged on the inner side of the anti-seepage ring, and the preparation method of the external tincture patch comprises the steps of traditional Chinese medicine processing, tincture extraction, patch forming and the like. The medicine is efficiently extracted through an ethanol solvent, transdermal absorption of the medicine is promoted, and the product is simple and convenient in preparation process, low in cost and convenient for a patient to use by himself or herself and carry daily.

The invention provides a traditional Chinese medicine composition for treating pulmonary arterial hypertension right heart failure, which is characterized in that the traditional Chinese medicine composition is prepared from the following raw material medicines: safflower carthamus, polygonum cuspidatum, semen lepidii, white mulberry root-bark and astragalus membranaceus. Various components in the traditional Chinese medicine composition are scientific in compatibility and play a synergistic effect, the cardio-pulmonary function of a right heart failure rat suffering from pulmonary arterial hypertension can be improved, the hemodynamics of pulmonary artery can be improved, the pathological damage and fibrosis degree of cardiac muscle tissue can be relieved, the inflammation level can be reduced, and the remarkable treatment effect on the right heart failure suffering from pulmonary arterial hypertension can be achieved; the clinical application value is higher, and the medical application prospect is wide.

This invention discloses a kidney-tonifying and blood-activating traditional Chinese medicine composition and its application in improving postoperative visual function, belonging to the field of pharmaceutical technology. The kidney-tonifying and blood-activating traditional Chinese medicine composition of this invention is made from 10 parts of Cuscuta chinensis, 15 parts of Broussonetia papyrifera fruit, 18 parts of Lycium barbarum, 15 parts of Leonurus japonicus, 20 parts of Leonurus japonicus, 10 parts of Ligusticum chuanxiong, 9 parts of Prunus persica kernel, 6 parts of Carthamus tinctorius, 15 parts of Poria cocos, 18 parts of Albizia julibrissin bark, 12 parts of Astragalus membranaceus, and 12 parts of Pueraria lobata root. It can be standardized and adjusted according to clinical complications. This invention focuses on the critical point of "kidney deficiency and blood stasis" one month after posterior scleral reinforcement surgery, using the principles of tonifying the liver and kidneys and activating blood circulation to improve ocular microcirculation, enhance and stabilize vision, thereby protecting visual function, and conforming to the treatment principle of "treating the root cause when the condition is mild."

The invention discloses a five-ingredient meconopsis Tibetan medicine composition as well as a preparation method and application thereof, and relates to the technical field of medicines, the five-ingredient meconopsis Tibetan medicine composition is prepared from the following raw material components in parts by mass: 80-120 parts of meconopsis, 30-70 parts of tabasheer, 80-120 parts of safflower, 80-120 parts of emblic leafflower fruit and 5-15 parts of saffron. The five-ingredient concentrated pill provided by the invention is prepared by adopting a new dosage form, a dosage form compared with a 25-ingredient meconopsis meconopsis pill is changed into the concentrated pill from a watered pill, and the pill is prepared by extracting and concentrating part of medicinal materials, so that the concentration of effective components of the concentrated pill is improved, the bioavailability is good, and the drug effect is improved; the concentrated pill is small in size, small in taking dosage, relatively concentrated in effective components and less in impurities; in the aspect of storage, the concentrated pill is more stable than a water pill and is convenient to carry and store.

The invention provides a tendon-relaxing, collateral-activating and pain-relieving breast plaster for shoulder, neck, lumbar vertebra, arthralgia and traumatic injury. The plaster is prepared from the following raw materials in parts by weight: 22-35 parts of frankincense, 41-55 parts of mirabilite, 26-40 parts of ligusticum wallichii, 31-40 parts of lycopodium clavatum, 5-20 parts of dragon's blood, 5-20 parts of pseudo-ginseng, 10-25 parts of radix clematidis, 40-55 parts of pawpaw, 35-45 parts of radix angelicae pubescentis, 40-50 parts of pericarpium zanthoxyli, 40-50 parts of ginger, 30-35 parts of rhizoma drynariae, 42-47 parts of radix aconiti kusnezoffii, 43-48 parts of radix aconiti, 45-50 parts of asarum, 40-50 parts of 20 to 30 parts of chamomile, 10 to 25 parts of menthol oil, 10 to 25 parts of camphor oil, 15 to 25 parts of lavender essential oil and 10 to 25 parts of wintergreen oil; 15-25 parts of radix saposhnikoviae oil, 15-25 parts of garden balsam stem oil and 15-30 parts of safflower oil. The ointment has special effects on shoulder, neck and lumbar vertebra, arthralgia, traumatic injury, tendon relaxing, collateral activating and pain relieving; and the traditional Chinese medicine composition has the effect of treating both symptoms and root causes without relapse and side effects.

The invention discloses a traditional Chinese medicine composition for treating ischemic stroke and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from, by weight, 7-10 parts of salvia miltiorrhiza, 10-20 parts of astragalus membranaceus, 4-8 parts of ligusticum wallichii, 2-4 parts of scalded leeches, 2-4 parts of ground beetles, 2-4 parts of gastrodia elata, 4-8 parts of scorpions, 4-8 parts of polygala tenuifolia, 4-8 parts of acorus tatarinowii, 7-10 parts of red peony roots, 4-8 parts of carthamus tinctorius, 4-8 parts of angelica sinensis and 4-8 parts of peach kernels. According to the application, the compatibility structure is rigorous, the primary and secondary effects are clear, through multi-target intervention (antithrombosis, blood flow improvement and nerve protection), the advantages of'compound compatibility and overall adjustment 'of traditional Chinese medicine are embodied, and the aspects of movement, vision, language, cognitive functions and the like are remarkably improved.

The utility model relates to a lifting device for a safflower oil canning bottle. Comprising a feeding assembly, the feeding assembly comprises a feeding conveying belt and limiting stoppers, the two limiting stoppers are arranged on the upper end face of the feeding conveying belt in parallel, and the multiple bottle bodies are distributed between the two limiting stoppers on the feeding conveying belt in an array mode; a lifting assembly comprises a first motor arranged on a rack, the output end of the first motor penetrates through the rack and then is connected with a mounting base, a first air cylinder is arranged on the mounting base, the output end of the first air cylinder is connected with a lifting component, and the lifting component extends into and abuts against the lower ends of bottle openings of a plurality of bottle bodies. And the plurality of bottle bodies are lifted up under the driving of the first air cylinder and move under the driving of the first motor. According to the filling bottle conveying device, the supporting piece extends into the position below the bottle bodies conveyed from the conveying belt in a driving mode, the quantitative bottle bodies are lifted up and conveyed to the next production procedure, and the effect of conveying the filling bottles in batches is achieved.

This invention relates to a highly effective pain-relieving pharmaceutical composition, comprising, by weight, 10-30 parts of Angelica sinensis, 10-30 parts of Chaenomeles speciosa, 10-30 parts of Paeonia lactiflora, 10-30 parts of Boswellia carterii, 10-30 parts of Eupolyphaga sinensis, 5-20 parts of Sappanwood, 5-20 parts of Carthamus tinctorius, 0.1-5 parts of Dracaena cochinchinensis, 5-20 parts of Syzygium aromaticum, 20-40 parts of Hibiscus mutabilis leaf, 20-40 parts of Citrus aurantium, 10-25 parts of Commiphora myrrha, and 20-40 parts of calcined natural copper. The pharmaceutical composition of this invention has advantages such as rapid onset of action, high therapeutic efficacy (≥96%), high significant efficacy (≥65%), low recurrence rate, prolonged recurrence interval, safety and effectiveness, and good patient compliance.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine health-care liquid with an inhibiting effect on pain as well as a preparation method and application of the traditional Chinese medicine health-care liquid. 6%-8% of radix angelicae pubescentis; 5-8% of divaricate saposhnikovia root; 6%-10% of angelica sinensis; 3%-6% of safflower; 0.3%-0.8% of free amino acid; 0.5%-1.2% of an accelerant; 0.05%-0.1% of a stabilizer; 0.01%-0.02% of a chelating agent and 3%-5% of corydalis tuber; 0.1% to 0.3% of borneol; 0.05%-0.1% of a pH regulator; and the balance pure water. The traditional Chinese medicine components such as illicium henryi, radix angelicae pubescentis and divaricate saposhnikovia root cooperate with one another to jointly and effectively relieve the pain part, meanwhile, the effective components can rapidly permeate the skin, the effect taking time is shortened, and the effect taking speed is higher.

The invention discloses a traditional Chinese medicine composition for treating lumbago and application of the traditional Chinese medicine composition. Rehmannia glutinosa, astragalus membranaceus and radix puerariae are used as monarch drugs; black prepared common monkshood daughter root, dried ginger, cassia twig, asarum, pseudo-ginseng, safflower and the like are used as ministerial drugs; gleditsia sinensis lam, semen brassicae, radix scutellariae, fructus arctii, radix paeoniae alba, fructus lycii, rhizoma atractylodis macrocephalae and the like are used as adjuvant drugs, radix bupleuri, cudrania cochinchinensis, radix dipsaci, eucommia ulmoides, herba epimedii and cynomorium songaricum are used as adjuvant drugs, radix bupleuri is used for soothing liver and regulating qi, and lifting qi to strengthen yang and warm qi, cudrania cochinchinensis is used for promoting blood circulation to remove meridian obstruction, and radix puerariae is used for relieving muscles and relaxing tendons and removing stasis and removing food retention. The traditional Chinese medicine can effectively treat kidney-yang deficiency type and complex lumbago (such as lumbar muscle degeneration, lumbar disc herniation and osteoarthritis), such as cold-dampness stasis and the like, treats both symptoms and root causes, and is not easy to relapse.

The invention belongs to the technical field of medicines, and particularly relates to safflower polysaccharide for lung targeting as well as a preparation method and application thereof. The safflower polysaccharide comprises the following monosaccharides in percentage by mole: 0.75% of L-fucose, 36.04% of arabinose, 25.03% of rhamnose, 17.85% of galactose, 4.26% of glucose, 1.33% of xylose, 0.61% of mannose, 12.07% of galacturonic acid and 2.06% of glucuronic acid, and the total percentage is 100%. The molecular weight of the safflower polysaccharide is 16.27 kDa. The safflower polysaccharide disclosed by the invention can be absorbed into blood within 24 hours and almost completely metabolized, and can be used for preparing lung targeting products.

The invention relates to a traditional Chinese medicine liquid and a traditional Chinese medicine ointment for expelling toxins from osteoporosis and a preparation method thereof. The traditional Chinese medicine liquid for expelling toxins from osteoporosis is prepared from the following raw materials in parts by weight: 10-15 parts of radix clematidis, 12-18 parts of trifid sopubia herb, 10-15 parts of garden balsam stem, 15-25 parts of suberect spatholobus stem, 6-10 parts of safflower, 9-12 parts of Chinese angelica, 6-8 parts of liquorice and 8-12 parts of folium artemisiae argyi. The preparation method of the bone seam detoxifying traditional Chinese medicine liquid comprises the following steps: a, pretreating the raw materials; b, decocting and extracting; c, filtering and concentrating; d, blending and homogenizing; and e, sterilizing and packaging. The traditional Chinese medicine liquid and the traditional Chinese medicine ointment for detoxifying the bone seams are particularly used for detoxifying toxins such as deep damp turbidity and phlegm stasis in the bone seams, and are suitable for relieving symptoms such as ankylosis, deep pain, hyperostosis and the like caused by deposition of toxins in the bone seams. The bone seam detoxification traditional Chinese medicine liquid and the traditional Chinese medicine ointment have the remarkable advantages of being high in seepage force, comprehensive in detoxification, high in safety, wide in applicability and the like.

The invention relates to a suppository for treating postpartum infection and metritis and a preparation method thereof. The suppository for treating postpartum infection and metritis comprises the following raw materials: active pharmaceutical ingredients and auxiliary materials, the mass ratio of the components is 1: (1-2.5). The active pharmaceutical ingredients comprise scutellaria baicalensis, safflower carthamus, angelica sinensis, radix angelicae, poria cocos, liquorice, codonopsis pilosula, radix bupleuri, radix sophorae flavescentis, rhizoma atractylodis and agastache rugosus; the auxiliary materials comprise a matrix and an additive. The suppository has the advantages of being capable of avoiding the first-pass effect of the liver, high in bioavailability, fast in effect taking, convenient to use and the like.

The invention discloses a traditional Chinese medicine composition for treating diabetic skin itch and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The composition is prepared from angelica sinensis, astragalus membranaceus, radix paeoniae rubra, cortex dictamni, rehmannia, ligusticum wallichii, scalded peach kernels, safflower carthamus, fried tribulus terrestris, divaricate saposhnikovia roots and cicada slough according to a specific weight ratio. On the basis of a classic famous formula of the Chinese angelica potion, the Chinese angelica potion is innovatively prepared aiming at the core pathogenesis of qi deficiency, blood stasis, damp-heat and wind-dryness of diabetic skin itch. The radix paeoniae rubra and the radix paeoniae alba are used for enhancing the effects of cooling blood and dissipating blood stasis; peach kernel and safflower are added to strengthen blood circulation activation and collateral dredging; cortex dictamni is added to enhance dampness eliminating and detoxification; cicada slough and herba schizonepetae are used for enhancing wind dispelling and heat clearing, and the nature is Polygonum multiflorum and liquorice are removed, so that the safety is improved. The whole formula has the effects of tonifying qi, promoting blood circulation, eliminating dampness, detoxifying, dispelling wind and moistening dryness. The invention also provides a preparation method of the composition. The composition can be used for preparing medicines for treating skin diseases such as diabetic skin itch and eczema, and is remarkable in curative effect and high in safety.

The invention relates to a traditional Chinese medicine extract composition for facial skin care, which is prepared by compatibility of raw radix astragali, stiff silkworm, radix angelicae, safflower and other traditional Chinese medicines through a supercritical CO2 extraction and alcohol extraction-water extraction combined process, the total flavone content is greater than or equal to 22%, and the total phenolic acid content is greater than or equal to 16%. The composition realizes a multi-target synergistic effect through a triple mechanism of tonifying qi and activating blood, soothing the liver and relieving depression, and detoxifying and repairing; the composition is capable of whitening and fading spots, inhibiting tyrosinase and reducing melanogenesis by 38%; hormonal dermatitis is repaired, the TEWL value is reduced by 28%, and IL-6 secretion is inhibited by 41%; anti-aging: promoting the expression of type I collagen to be increased by 42%, and improving the depth of wrinkles by 29%. The composition cooperates with modern active ingredients such as retinol palmitate and hexapeptide, and innovative carriers such as biological fiber membrane cloth (the oxygen permeation rate is increased by 3 times) and freeze-dried powder dosage forms are carried, so that efficient permeation and stability are ensured. The composition is suitable for whitening skin care products, hormonal dermatitis treatment products and anti-aging preparations, and solves the problems of single efficacy and insufficient safety in the prior art.

This invention belongs to the technical field of skin disease treatment products, specifically relating to a topical hot compress for treating scleroderma and its preparation method. The topical hot compress for treating scleroderma is made from the following raw materials in parts by weight: 20-40 parts of Artemisia argyi, 20-40 parts of Cinnamomum cassia, 10-20 parts of Sparganium stoloniferum, 10-20 parts of Curcuma zedoaria, 10-20 parts of Loranthus parasiticus, 15-30 parts of Gynostemma pentaphyllum, 10-20 parts of Spirodela polyrhiza, 15-30 parts of Spirodela polyrhiza, 15-30 parts of Ephedra sinica, 20-40 parts of Clematis chinensis, 5-15 parts of Eupolyphaga sinensis, 15-25 parts of Eriocaulon buergerianum, 5-15 parts of Carthamus tinctorius, 3-6 parts of Dracaena cochinchinensis, 3-6 parts of processed Strychnos nux-vomica, 20-40 parts of Vaccaria segetalis, 20-40 parts of Astragalus membranaceus, 10-20 parts of Magnolia officinalis, 10-20 parts of Aconitum carmichaelii, and 22-40 parts of rice wine. This invention is a topical medication that eliminates the need for oral administration, treating the disease externally and guiding the pathogenic factors to a cure. It avoids the inconvenience of bitter medications and effectively relieves symptoms and promotes the cure of localized scleroderma.

The traditional Chinese medicine composition is prepared from the following components in parts by weight: 5 to 25 parts of radix angelicae sinensis, 3 to 20 parts of rhizoma chuanxiong, 6 to 30 parts of radix salviae miltiorrhizae, 5 to 26 parts of flos carthami, 3 to 25 parts of radix paeoniae rubra, 2 to 22 parts of radix trichosanthis, 6 to 25 parts of bulbus fritillariae cirrhosae, 6 to 20 parts of frankincense, 5 to 25 parts of myrrh, 3 to 30 parts of fructus gardeniae, 3 to 26 parts of fructus forsythiae, 5 to 30 parts of flos lonicerae, 5 to 25 parts of herba violae, 5 to 30 parts of spina gleditsiae, 3 to 30 parts of caulis bambusae in taeniam, 3 to 30 parts of herba taraxaci, 5 to 25 parts of radix rehmanniae and 3 to 30 parts of radix scrophulariae. The invention provides a prescription of angelica sinensis, ligusticum wallichii, salvia miltiorrhiza, safflower, radix paeoniae rubra, radices trichosanthis, fritillaria, frankincense, myrrh, gardenia, fructus forsythiae, honeysuckle, bunge corydalis herb, spina gleditsiae, caulis bambusae in taeniam, dandelion, radix rehmanniae and radix scrophulariae, all the medicines supplement one another, the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, reducing swelling and removing stasis and cooling blood can be achieved, and the traditional Chinese medicine has a good effect on treating whelks.

The invention discloses a traditional Chinese medicine liniment for treating lumbocrural pain and hyperostosis and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine liniment is prepared from notopterygium root, radix angelicae pubescentis, angelica sinensis, fructus lycii, flos carthami, clove and radix saposhnikoviae according to a specific weight part ratio through soaking in wine and extracting, and auxiliary materials such as glycerol can also be added according to requirements. The traditional Chinese medicine composition is scientific in formula, integrates functions of promoting blood circulation to remove blood stasis, dispelling wind and eliminating dampness and tonifying liver and kidney, and is high in permeability, quick in effect, good in stability and small in side effect. The preparation method adopts a percolation method for extraction, so that effective components can be reserved to the greatest extent, and stable quality of liquid medicine is ensured. The traditional Chinese medicine can be used for effectively treating arthralgia such as lumbocrural pain, hyperostosis, lumbar disc herniation, rheumatic arthritis and the like, and has good clinical application value.