688 results about "Frankincense" patented technology

The present invention relates to the technical field of new drug indications, and specifically discloses a non-filling breast augmentation external skin-rejuvenating oil preparation and its preparation method and application. The preparation method of the external skin-rejuvenating oil preparation is as follows: (1) preparing a skin-rejuvenating oil alcohol extract freeze-dried powder: taking astragalus, angelica, epimedium, ginkgo, green peel, frankincense, rhubarb, chicken gizzard, scutellaria, coptis, phellodendron and borneol in a certain weight ratio and adding them together into a container, and then adding an ethanol solution with a volume fraction of 40%-70% to the container, soaking, flash extraction, filtrate concentration, freeze drying to obtain; (2) preparing a skin-rejuvenating oil preparation: dissolving the skin-rejuvenating oil alcohol extract freeze-dried powder and egg yolk lecithin in edible vegetable oil to obtain an oil phase; then dripping the oil phase into the water phase obtained by dissolving Tween 60 and glycerol in ultrapure water, stirring and high-speed shearing, high-pressure homogenization, and obtaining. The external skin-rejuvenating oil preparation of the present invention has the effect of promoting breast fullness and uprightness in a short period of time.

The invention provides a traditional Chinese medicine gel patch for treating gouty arthritis and a preparation method thereof. The traditional Chinese medicine gel patch for treating gouty arthritis comprises at least a gel layer loaded with traditional Chinese medicine extracts; the traditional Chinese medicine extracts comprise the following raw materials: coix seed, phellodendron amurense, clematis root, radix scutellariae, atractylodes lancea, radix ophiopogonis, radix scutellariae, acer scutellariae, radix scutellariae, radix aconiti kusnezoffii, radix strychnii, frankincense, myrrh, angelica sinensis, safflower, cyathula root, radix paeoniae rubra, radix smilacis gracile, radix striatae, eucalyptus glomeratae, sophora flavescens, andrographis paniculatae, radix lobeliae, rhizoma coptidis, radix scutellariae, cassia twig, zanthoxylum bungeanum, and borneol; and a matrix of the gel layer comprises the following raw materials in parts by weight: silk fibroin, polyvinyl pyrrolidone, azido-polyethylene glycol-carboxylic acid, 1-ethynylcyclopropylcarboxylic acid, 2,5-dicarboxylic acid-3,4-ethylenedioxythiophene, and glycerol. The traditional Chinese medicine gel plaster of the present invention can achieve good therapeutic effects through percutaneous absorption.

The invention belongs to the technical field of application of natural extracts, and particularly discloses application of Boswellia amoena essential oil in prevention and treatment of aquatic diseases, in particular application of Boswellia amoena essential oil in inhibition of shewanella algal and vibrio alginolyticus. According to the application, various plant essential oils are tested, the bacteriostatic activity of the plant essential oils on two marine vibrios, i.e., shewanella alginate and vibrio alginolyticus, is researched by a filter paper method and a gradient dilution method, and GC-MS analysis is further performed on several essential oils; according to comprehensive analysis, the frankincense Aman has a remarkable effect on inhibiting shewanella and vibrio alginolyticus, and reference can be provided for application of the frankincense Aman essential oil to prevention and treatment of aquatic diseases.

The invention discloses a medicine paste for promoting fracture healing and a preparation method thereof, and belongs to the field of external traumatic medicines. The specific preparation method comprises the following steps: mixing traumatology medicine liquid and distilled water according to the volume part ratio of 1: 1 to obtain mixed liquid, taking a proper amount of bone setting medicine powder, and blending into paste by using the mixed liquid. Wherein the bone setting medicine powder is prepared from the following components in parts by weight: 50 parts of fructus gardeniae, 30 parts of cacumen biotae, 100 parts of rhizoma drynariae, 30 parts of rhizoma polygoni cuspidati, 50 parts of ground beetles, 20 parts of radix cynanchi paniculati, 100 parts of rhizoma curcumae longae, 20 parts of frankincense and 20 parts of myrrh. The medicine paste has the effects of promoting blood circulation to remove blood stasis and promoting bone recovery.

The invention relates to the technical field of traditional Chinese medicine pharmacy, and discloses a traditional Chinese medicine micro-powder capsule based on functions of promoting blood circulation to remove blood stasis, dispelling wind and eliminating dampness and activating meridians to stop pain. 0.8%-1.2% of scorpion; 0.8%-1.2% of Chinese polyphaga; 0.8%-1.2% of safflower carthamus; 0.8%-1.2% of peach kernels; 0.8%-1.2% of zaocys dhumnade; 0.8% to 1.2% of frankincense; 0.8%-1.2% of ligusticum wallichii; 0.8%-1.2% of cortex moutan; 0.8% to 1.2% of myrrh; 0.8%-1.2% of notopterygium root; 0.8%-1.2% of radix angelicae pubescentis; 0.8%-1.2% of fructus lycii; 0.8%-1.2% of centipede; 15%-25% of a functional auxiliary material: 3%-5% of a nano dispersion carrier; and 3%-5% of an inclusion compound. By adopting a beta-cyclodextrin inclusion technology, volatile oil and a humid and hot environment can be effectively isolated, the stability of the volatile oil can be enhanced, by taking ligustrazine as an example, under an accelerated test condition, the retention rate of the ligustrazine in 6 months is up to 89.5%, and compared with a non-inclusion condition, the retention rate is improved, the degradation rate is reduced by 3.1 times, and the stability of the core component for promoting blood circulation to remove blood stasis in the storage and use process is ensured.

This invention discloses a method for preparing a pH / glucose dual-responsive chronic wound dressing containing frankincense essential oil, comprising: (1) using 4-formaldehyde phenylboronic acid as a crosslinking agent to form Schiff base and borate ester bonds with carboxymethyl chitosan and two different molecular weight hyaluronic acids, respectively, to prepare a hydrogel capable of filling skin surface wounds and performing dual dynamic covalent crosslinking adhesion, and freeze-drying for later use; (2) preparing frankincense essential oil into microcapsules by emulsification coagulation method, and freeze-drying for later use; (3) mixing the hydrogel with the freeze-dried powder of frankincense essential oil microcapsules, adding deionized water or PBS and stirring to reconstitute to form a pH / glucose dual-responsive hybrid hydrogel dressing coated with frankincense essential oil microcapsules. The composite dressing prepared by this invention has anti-inflammatory, antioxidant, antibacterial, and healing-promoting effects, is quick and easy to prepare, and has the ability to respond to the acidic / high-glucose microenvironment of diabetic wounds, and has important practical application value.

The present invention relates to a traditional Chinese medicine composition and a medicine for promoting wound healing. The active ingredients of the traditional Chinese medicine composition are prepared from the following raw materials in parts by weight: 30-50 parts of Centella asiatica, 10-20 parts of Lithospermum officinale, 5-20 parts of Bletilla striata, 5-20 parts of Chrysanthemum indica, 10-30 parts of Platycodon grandiflorum, 5-20 parts of Folium Isatidis, and 5-15 parts of Olibanum. The Chinese medicine composition of the present invention is composed of appropriate amounts of Centella asiatica, Lithospermum officinale, Bletilla striata, Chrysanthemum indica, Platycodon grandiflorum, Folium Isatidis and Olibanum. In the prescription, Centella asiatica can clear away heat and dampness, detoxify and reduce swelling, and Centella asiatica is used as the main medicine; Lithospermum officinale can cool blood and activate blood circulation, detoxify and cure rashes; Chrysanthemum indica can disperse wind-heat, reduce swelling and detoxify; Folium Isatidis can clear heat and detoxify, cool blood and eliminate spots, and assist the main medicine in clearing heat and detoxifying, and serves as the minister medicine; Platycodon grandiflorum is used to discharge pus, and Bletilla striata can astringe and stop bleeding, reduce swelling and promote tissue regeneration, and assist the main medicine and the minister medicine in reducing swelling and detoxifying; Olibanum can promote blood circulation and qi circulation, so that the drug effect can directly reach the diseased area; all the medicines can play the functions of clearing heat and detoxifying, reducing swelling and promoting tissue regeneration, and promote wound healing.

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for relieving pain, promoting blood circulation, diminishing swelling and removing blood stasis, application thereof and a blood stasis dispersing and pain relieving patch. The invention provides a traditional Chinese medicine composition for relieving pain, activating blood, diminishing swelling and removing stasis. The traditional Chinese medicine composition comprises the following components: lycopodium clavatum, radix clematidis, asarum, gentiana macrophylla, radix angelicae, rheum officinale, notopterygium root, roasted herba epimedii, radix achyranthis bidentatae, peach kernel, radix angelicae pubescentis, vinegar-processed rhizoma corydalis, vinegar-processed rhizoma cyperi, moutan bark, prepared kusnezoff monkshood root, prepared monkshood, vinegar-processed frankincense, Sinkiang lithospermum, vinegar-processed myrrh and sanguisorba officinalis. The blood stasis dispersing and pain relieving patch has the advantages of being good in curative effect, quick in effect taking, convenient to use, safe and reliable, can be used for treating traumatic injuries and pain caused by cervical spondylosis, scapulohumeral periarthritis, lumbar disc herniation, lumbar vertebrae hyperosteogeny, spinal stenosis, sciatica, ankylosing spondylitis, arthritis and other diseases, and can achieve the effect of treating both symptoms and root causes.

The invention discloses a phlebitis treatment gel containing a coptis chinensis-wine-treated rhubarb compound component and a preparation method of the phlebitis treatment gel. The active ingredients of the gel are coptis chinensis, rheum officinale and wine-treated rheum officinale in a mass ratio of (1.5-2.5): (1.5-2.5): 1, preferably 2: 2: 1. Lavender essential oil, tea tree essential oil, folium eucalypti essential oil and vinegar frankincense, radix trichosanthis and other traditional Chinese medicine auxiliary materials are used as auxiliary materials. The preparation method comprises the following steps: extracting twice with ethanol, mixing extracting solutions, adding borneol, menthol and essential oil, and finally gelling with carbomer. The phlebitis gel can be independently used or combined with indometacin to form dual-channel anti-inflammation, and the defects of skin atrophy, toxicity accumulation and the like of traditional phlebitis gel are overcome. The traditional Chinese medicine composition is clinically expanded and applied to first-stage pressure sores (without skin damage), acnes and mosquito bites, red and swollen of the first-stage pressure sores fade away within 3-5 days, red and swollen of the acnes are relieved by more than or equal to 60% when the traditional Chinese medicine composition is combined with oral medicine for 48 hours, the itching relieving effect on the mosquito bites is less than or equal to 30 minutes, and the curative effect on phlebitis is remarkably superior to that of 50% magnesium sulfate (Plt;

The invention discloses a hydrogel patch for promoting blood circulation to remove meridian obstruction and a preparation method thereof. The formula of the hydrogel patch for promoting blood circulation to remove meridian obstruction comprises a traditional Chinese medicine concentrated solution for promoting blood circulation to remove meridian obstruction, an oil-in-water emulsion for promoting blood circulation to remove meridian obstruction, sodium polyacrylate, polyacrylic acid, glycerol, azone, dihydroxyaluminum aminoacetate, tartaric acid, disodium ethylene diamine tetraacetate, methylparaben and deionized water. The traditional Chinese medicine concentrated solution for promoting blood circulation to remove meridian obstruction is 70% ethanol extract of vinegar-processed rhizoma corydalis, ligusticum wallichii, philippine flemingia root, safflower, frankincense, myrrh, radix angelicae and liquorice; the oil-in-water emulsion capable of promoting blood circulation to remove meridian obstruction is prepared from a vinegar rhizoma corydalis sesame oil extract, wintergreen oil, methyl glucose sesquistearate, stearate, cetostearyl alcohol, polydimethylsiloxane and deionized water; the blood-activating collateral-dredging hydrogel patch has no skin irritation, belongs to weak sensitization, and has the function of assisting in relieving pain.

The invention discloses a novel drug-loaded soluble microneedle for promoting healing of diabetic ulcer and a preparation method of the novel drug-loaded soluble microneedle. The microneedle comprises effective component extracts in lipidosome, hyaluronic acid, frankincense and myrrh. The carried medicine is a classical medicine pair with tissue regeneration promoting and sore astringing, namely frankincense-myrrh, and the key active ingredients for treating the diabetic ulcer are screened out by adopting artificial intelligence-based molecular docking and network target technologies, and biological verification is carried out on the action mechanism of the key active ingredients; by adopting the carrier system and the existing components lipidosome and hyaluronic acid in the organism, the material has extremely high biocompatibility and no toxic or side effect, and shows good stability in the subsequent test, so that the time and difficulty of clinical medicine replacement are greatly reduced; the preparation process of the drug-loaded microneedle is simple, conventional equipment is used, raw materials are easy to obtain, the drug-loaded microneedle is safe, pollution-free and low in cost, economic and mental burdens of patients are relieved, and the drug-loaded microneedle has good popularization and application prospects.

The invention relates to the technical field of traditional Chinese medicine, and discloses a plaster for treating bone fracture and a preparation method thereof, and the plaster comprises the following raw materials: peach kernel, safflower, ligusticum wallichii, radix cyathulae, rhizoma drynariae, radix angelicae pubescentis, notopterygium root, eucommia ulmoides, astragalus membranaceus, pseudo-ginseng, native copper, dragon's blood, catechu, angelica sinensis, radix rehmanniae, gentiana macrophylla, radix saposhnikoviae, earthworm, centipede, scorpion, ground beetle, liquorice, frankincense, myrrh, yellow lead, sesame oil and other auxiliary materials. Pseudo-ginseng is added into the formula, the effects of promoting blood circulation to remove blood stasis, diminishing swelling and relieving pain of pseudo-ginseng are utilized, absorption of blood stasis of the bone fracture part can be accelerated, then pain and swelling caused by blood stasis blocking are remarkably relieved, blood circulation is promoted, and injury repair is promoted, and radix angelicae sinensis and radix rehmanniae are added into the formula, and the effects of replenishing blood and promoting blood circulation of radix angelicae sinensis and nourishing yin and cooling blood of radix rehmanniae are utilized, so that the bone fracture can be cured, and the bone fracture can be cured. And blood generation and local microcirculation improvement can be promoted, so that the blood supply and oxygen supply capacity of a bone fracture repair part is enhanced, and soft tissue repair is accelerated.

The invention discloses a preparation method of a pH / glucose double-response chronic wound dressing containing frankincense essential oil, which comprises the following steps: (1) respectively forming Schiff base and boric acid ester bonds with carboxymethyl chitosan and two hyaluronic acids with different molecular weights by using 4-formylphenylboronic acid as a cross-linking agent; preparing adhesive hydrogel which can be used for skin surface wound surface filling and double-dynamic covalent cross-linking, and freeze-drying for later use; (2) preparing the frankincense essential oil into microcapsules by an emulsification and condensation method, and freeze-drying for later use; and (3) mixing the hydrogel with the freeze-dried powder of the frankincense essential oil microcapsules, adding deionized water or PBS, stirring and redissolving to form the pH / glucose double-response hybrid hydrogel dressing coated with the frankincense essential oil microcapsules. The composite dressing prepared by the invention has the effects of resisting inflammation, resisting oxidation, resisting bacteria and promoting healing, is quick and simple to prepare, has stimulation response capability on acid / high-glucose microenvironment of diabetic wound surfaces, and has important practical application value.

The present invention discloses a natural firming, anti-wrinkle and brightening plant essential oil in the field of skin care products, its preparation method and application. The components of the essential oil include frankincense oil, sandalwood oil, lavender oil, myrrh oil, helichrysum italicum oil, cistus ladaniferus oil, rosa damascena flower oil, vetiver root oil, and marine biological sterols. The marine biological sterols are composed of a mixture of ascidiasterol and sarcophytol A. This plant essential oil can be applied in skin care products such as aqueous solutions, facial masks, essence, lotions, creams, and liquid foundations. The present invention adopts a unique essential oil formula, making the product outstanding in the comprehensive effect of anti-wrinkle and brightening, and without any chemical components, and all comply with the relevant regulations of the "Technical Specifications for Cosmetics Safety", with high safety. In the plant essential oil of the present invention, marine biological sterols made of ascidiasterol and sarcophytol A are added, which have the effects of antioxidant and moisturizing by themselves, and can also improve the penetration and absorption of the essential oil, thereby further enhancing the anti-wrinkle and brightening effects.

The invention belongs to the technical field of essential oil patches, and discloses a slow-release sleep-aiding essential oil patch and an essential oil formula. The essential oil patch comprises a surface layer, an essential oil layer, an isolating layer, a sticking layer and a protective layer, the essential oil layer contains a sustained-release microcapsule, and the sustained-release microcapsule comprises a microcapsule wall material and a sustained-release sleep-aiding essential oil core material. The essential oil formula comprises the following raw materials: lavender essential oil, sandalwood essential oil, pelargonium graveolens essential oil, bergamot fruit essential oil, vetiver root essential oil, rose essential oil, eucalyptus globulus leaf essential oil, frankincense essential oil and manuka essential oil. According to the slow-release sleep-aiding essential oil patch, the sleep-aiding essential oil is wrapped in a microcapsule form, so that the sleep-aiding essential oil can be slowly released, the fragrance can be continuously retained, and the sleep of a human body can be assisted. The raw materials of the sleep-aiding essential oil are all natural essential oil, drug dependence and side effects are avoided, the essential oil raw materials are all processed into small molecular structures, the small molecular essential oil can rapidly make contact with respiratory mucosa and permeate into a blood circulation system through blood vessels and lymphatic vessels to play a role, and the sleep-aiding essential oil is rapid in effect taking and high in practicability.

The invention discloses a traditional Chinese medicine composition for treating lumbago, and relates to the field of traditional Chinese medicines, and the traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials: rhizoma drynariae, teasel root, eucommia ulmoides, caulis spatholobi, dragon's blood, catechu, frankincense, myrrh, safflower, ground beetle, native copper and radix aconiti preparata. The traditional Chinese medicine composition is free of side effects, remarkable in effect and high in cure rate, a patient lies on the bed in a prostrate mode, a physician conducts hot compress for 3-5 min with a clean hot towel and then conducts wet hot compress with medicine liquid, the temperature of the medicine liquid is controlled to be 50-60 DEG C, and 25-35 min is conducted every time. A doctor puts sterile gauze into the hot liquid medicine to be completely soaked, clamps the two ends of the gauze with haemostatic forceps or tweezers, twists the gauze until no water drops, applies the gauze to the lumbago position, replaces the gauze every 3-5 minutes, and wraps the gauze with a plastic film to keep the temperature and humidity. The curative effect is observed as follows: the lumbago symptom is improved after hot compress treatment for 7 days. The treatment is carried out for 7 days after the second diagnosis, the treatment is carried out twice every 8 hours every day, and each time lasts for 30 minutes. And lumbago does not occur in the third diagnosis.

The invention provides a traditional Chinese medicine gel emplastrum for treating gouty arthritis and a preparation method thereof, the traditional Chinese medicine gel emplastrum for treating gouty arthritis at least comprises a gel layer loaded with a traditional Chinese medicine extract, the traditional Chinese medicine extract comprises the following raw materials: semen coicis, cortex phellodendri, radix clematidis, kadsura coccinea, rhizoma atractylodis, rhizoma dioscoreae hypoglaucae, red psychotria leaf, alangium platanifolium, kadsura pepper stem, radix aconiti, radix aconiti agrestis, semen strychni, frankincense, myrrh, angelica sinensis, safflower carthamus, radix cyathulae, radix paeoniae rubra, rhizoma smilacis glabrae, lycopodium clavatum, radices hemerocallis, weeping willow twig, evodia lepta, swamp mahogany, radix sophorae flavescentis, herba andrographitis, Chinese lobelia, coptis chinensis, edible tulip, cassia twig, pepper and borneol; a matrix of the gel layer is prepared from the following raw materials in parts by weight: silk fibroin, polyvinyl pyrrolidone, azide-polyethylene glycol-carboxylic acid, 1-ethynyl cyclopropyl carboxylic acid, 2, 5-dicarboxylic acid-3, 4-ethylenedioxythiophene and glycerol. The traditional Chinese medicine gel emplastrum disclosed by the invention can achieve a good treatment effect through percutaneous absorption.

The invention relates to the technical field of traditional Chinese medicine compositions, and discloses a traditional Chinese medicine composition for wound healing and a preparation method thereof.The traditional Chinese medicine composition used in the early stage comprises 10-12 parts of rheum officinale, 5-6 parts of coptis chinensis, 10-12 parts of scutellaria baicalensis, 10-12 parts of golden cypress, 10-12 parts of corydalis tuber, 6-7 parts of pseudo-ginseng, 5-6 parts of pollen typhae, 4-5 parts of dragon's blood, 10-12 parts of sanguisorba officinalis, 10-13 parts of ramulus mori and 10-12 parts of gallnut; the traditional Chinese medicine composition used in the middle stage is prepared from 10-12 parts of radix astragali, 10-12 parts of radix angelicae sinensis, 10-12 parts of radix salviae miltiorrhizae, 10-12 parts of talc, 10-12 parts of ramulus mori, 10-12 parts of gallnut, 10-12 parts of rhizoma chuanxiong, 4-5 parts of resina draconis, 10-12 parts of frankincense and 10-12 parts of myrrh; the traditional Chinese medicine composition used in the later period comprises 10-12 parts of radix astragali, 10-12 parts of radix dipsaci, 10-12 parts of radix angelicae sinensis, 10-12 parts of rhizoma chuanxiong, 10-12 parts of gallnut, 10-12 parts of ramulus mori, 10-12 parts of radix codonopsis, 10-12 parts of radix salviae miltiorrhizae, 10-12 parts of radix morindae officinalis and 10-12 parts of talc. Wound treatment is divided into three stages, the cure rate of chronic refractory wounds (CRW) can be remarkably increased, inflammatory factors are inhibited, and tissue regeneration is promoted.

The invention relates to the technical field of mastopathy medicines, and discloses a traditional Chinese medicine patch for treating breast nodules and a preparation process thereof. The traditional Chinese medicine patch comprises the following raw materials: safflower, pollen typhae, caulis spatholobi, angelica sinensis, trogopterus dung, lumbricus, gastrodia elata, pseudo-ginseng, cassia twig, thunberg fritillary bulb, frankincense, endothelium corneum gigeriae galli, rhizoma atractylodis, platycodon grandiflorum, curcuma zedoary, radix semiaquilegiae, radix bupleuri and salvia miltiorrhiza. Through reasonable compatibility of the raw materials and effective extraction of the active ingredients of the traditional Chinese medicines, the effects of the raw materials can be maximized, all the components have a synergistic effect, the permeability is high, the efficacy is lasting, and the traditional Chinese medicine preparation has the effects of soothing liver and regulating qi, promoting blood circulation to remove meridian obstruction, eliminating stasis and dissipating binds, clearing heat and dispelling wind, and nourishing yin and relieving pain; the traditional Chinese medicine composition has obvious curative effects on various breast diseases such as breast nodules, hyperplasia of mammary glands, pains, lumps and the like, the nodules disappear, and the mammary glands basically have no pains and uncomfortable symptoms.

The invention discloses a Chinese herbal medicine composition for softening hardness to dissipate stagnation, and relates to the technical field of Chinese herbal medicines. The Chinese herbal medicine composition for softening hardness to dissipate stagnation comprises the following components in parts by weight: 5-9 parts of pangolin scales, 3-10 parts of curcuma zedoary, 9-15 parts of salvia miltiorrhiza, 6-10 parts of mirabilite, 1-5 parts of ligusticum wallichii, 0.5-1 part of dragon's blood, 3-9 parts of safflower, 5-9 parts of rhizoma corydalis, 1-3 parts of frankincense, 5-7 parts of rheum officinale, 10-20 parts of oyster, 1-5 parts of thunberg fritillary bulb, 2-4 parts of kelp, 6-10 parts of clove, 6-10 parts of radix curcumae and 6-10 parts of earthworm. The Chinese herbal medicine composition for softening hardness to dissipate stagnation has good inhibition and improvement effects on nodules and tumors.

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating burns and scalds as well as a preparation method and application of the traditional Chinese medicine composition. The composition A is prepared from the following raw materials in parts by weight: 200 to 300 parts of raw radix et rhizoma rhei, 80 to 120 parts of cortex phellodendri, 80 to 120 parts of pericarpium citri reticulatae, 80 to 120 parts of raw rhizoma atractylodis, 45 to 55 parts of indigo naturalis and 15 to 25 parts of borneol; the composition B is prepared from the following raw materials in parts by weight: 80 to 120 parts of radix scutellariae, 80 to 120 parts of radix rehmanniae, 80 to 120 parts of cortex phellodendri, 4 to 6 parts of musk, 80 to 120 parts of radix angelicae sinensis, 80 to 120 parts of semen persicae and 80 to 120 parts of herba ephedrae; the composition C is prepared from the following raw materials in parts by weight: 50 to 70 parts of frankincense, 50 to 70 parts of myrrh, 25 to 35 parts of catechu, 25 to 35 parts of calcined gypsum, 25 to 35 parts of gypsum rubrum and 50 to 70 parts of cuttlebone. According to the technical scheme, dialectical treatment is carried out according to different stages of burn degrees, recovery is fast, patients can accept the traditional Chinese medicine easily, and the effect is good.

The invention relates to the technical field of external traditional Chinese medicine plasters, in particular to a yang-activating, cold-removing and pain-relieving ointment and a preparation method thereof. The analgesic ointment is prepared by taking black sesame oil and yellow lead as matrixes and assisting coarse medicinal materials with the effects of warming yang, dispelling cold, promoting blood circulation and dredging collaterals and fine medicinal materials (musk, camphor, myrrh, frankincense and the like) through the steps of treating the medicinal materials, extracting, refining oil, adding the yellow lead to form the ointment, removing fire toxin, adding the fine materials, spreading and the like. The traditional Chinese medicine composition does not contain western medicine components, can warm yang and dredge vessels, dispel cold and wind and eliminate dampness, promote blood circulation to remove meridian obstruction and remove blood stasis, and relieve swelling and pain, and is suitable for treating various orthopedic and rheumatism diseases such as acute and chronic lumbar and cervical diseases, knee joint hyperosteogeny, sciatica and scapulohumeral periarthritis. The ointment is large in drug loading capacity, capable of being administrated for a long time, good in long-term curative effect, not prone to relapse after healing, capable of being directly applied without heating, convenient to use, free of deterioration in two years at the normal temperature, small in irritation, low in anaphylaxis and high in safety.

This invention discloses a muscle-relaxing and meridian-clearing health powder and its preparation and application methods, belonging to the technical field of traditional Chinese medicine external health care products. The health powder is composed of fifteen raw medicinal materials: safflower, angelica, asarum, kudzu root, red peony root, scutellaria, dragon's blood, saposhnikovia root, frankincense, myrrh, cinnamon twig, mugwort leaf, coptis root, *Lycopodium clavatum*, and *Clematis armandii*. These materials are dried, pulverized to 80-120 mesh, and then evenly mixed. This invention, through a unique formulation design, integrates multiple effects such as promoting blood circulation and removing blood stasis, dispelling wind and cold, relieving muscle tension and clearing meridians, and clearing heat and drying dampness. Combined with a refined pulverization process, it significantly improves the dissolution rate and transdermal absorption efficiency of the drugs. During use, a hot compress applied via steam allows the medicinal properties to directly reach the affected area, effectively relieving pain and discomfort in the neck, shoulders, waist, legs, and joints. This invention's product has a scientific formulation, advanced technology, is convenient to use, and highly safe, possessing broad market application prospects.

The invention discloses an esophageal cancer targeting nano-tablet based on a traditional Chinese medicine composition and a preparation method of the esophageal cancer targeting nano-tablet. The targeted nano tablet is prepared from the following refined extracts: a rhizoma paridis total saponin extract, a pseudobulbus cremastrae seu pleiones colchicine derivative extract, a panax notoginseng total saponin extract, a carthamin yellow extract, a thunberg fritillary bulb total alkaloid extract, frankincense-myrrh compound volatile oil, a resin extract and an astragaloside IV extract. The nano-carrier comprises a nano-carrier, a seaweed-laminarin composite extract, a processed rhizoma pinelliae total alkaloid extract and costus root volatile oil, and the costus root volatile oil serves as one of targeting ligands to be used for modifying the nano-carrier. The targeting property is strong: the dual-targeting ligand (costunolide-TOPK affinity peptide) on the surface of the nano-carrier can actively recognize and combine with a specific receptor of esophageal cancer cells, and meanwhile, due to the size (about 100-200 nanometers) of the carrier, the carrier is easy to enrich in tumor tissues through enhanced permeation and retention (EPR) effect, so that the modernization upgrading of the idea of'channel guiding medicine 'is realized.

This application relates to the field of skin care products. More specifically, it relates to a facial essential oil and a preparation method thereof. A facial essential oil, by mass percentage, at least includes the following raw materials: 0.001-0.03% Cardiospermum halicacabum flower / leaf / vine extract, 0.1-1% Citrus nobilis Lour. peel oil, 0.1-1% Boswellia carterii oil, 0.8-1.5% bakuchiol, and the base oil makes up the balance; the preparation method is: mixing various raw materials until uniform to obtain the facial essential oil. This application has the advantages of reducing the greasiness brought by the facial essential oil to people with oily skin, moisturizing and controlling oil, maintaining the water-oil balance, improving skin elasticity, and rapid absorption.

The invention provides a traditional Chinese medicine composition for relieving or treating qi stagnation and blood stasis type bone diseases including osteoarthritis, fracture delayed healing and osteoporosis and a preparation method and application of the traditional Chinese medicine composition, and the traditional Chinese medicine composition comprises, by weight, 6-12 parts of radix paeoniae rubra, 10-20 parts of angelica sinensis, 10-20 parts of ligusticum wallichii, 10-15 parts of carthamus tinctorius and 15-25 parts of vinegar frankincense. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 15-25 parts of vinegar myrrh, 3-8 parts of borax, 6-12 parts of wine-treated rhubarb, 3-8 parts of dragon's blood, 10-20 parts of pseudo-ginseng, 3-7 parts of fried semen persicae, 3-7 parts of radix aucklandiae, 3-8 parts of vinegar-treated rhizoma cyperi, 20-30 parts of scalded rhizoma drynariae, 8-15 parts of radix achyranthis bidentatae, 6-10 parts of cortex lycii radicis, 6-10 parts of cortex acanthopanacis, 20-30 parts of crabs and 5-10 parts of radix dipsaci slices. The traditional Chinese medicine composition can promote qi to activate blood, relieve swelling and pain, reunion bones and reunion and promote healing, and has no toxic or side effect.

The invention relates to a traumatic injury pill and a preparation method thereof. The twenty traditional Chinese medicinal materials are selected, the production method is optimized according to different characteristics of the traditional Chinese medicinal materials, the Chinese angelica, the divaricate saposhnikovia root and the cassia twig contain volatile components and cannot be treated at a high temperature, temperature-controlled crushing needs to be performed preferentially, and the fried frankincense, the fried myrrh and the catechu are easy to soften in the crushing process, are adhered to a crusher and are not easy to crush, so that the traditional Chinese medicinal materials are difficult to crush. And finally, the powder is mixed and crushed with other medicinal powder, so that the crushing effect can be effectively improved. The obtained traumatic injury pill has the effects of promoting blood circulation to remove blood stasis, relieving swelling and pain and promoting reunion of fractured tendons and bones, and can be used for traumatic injury, tendon fracture and blood stasis swelling and pain.

The invention discloses a pharmaceutical composition, which comprises more than 28 substances, and is prepared by mixing water extracts of radix aucklandiae, agilawood, fructus choerospondiatis, fructus chebulae, myristica fragrans, kapok and frankincense, ethanol extracts of decoction dregs of the water extracts and travertine. The composition can improve myocardial ischemia of a subject; the cardiac ejection fraction of a myocardial infarction subject is increased; the cardiac minor axis shortening rate of a myocardial infarction subject is increased; reducing the inner diameter of the left ventricular end diastole of the myocardial infarction subject; the heart left ventricular systolic end inner diameter of a myocardial infarction subject is reduced.

The invention relates to application of a detoxifying and tissue regeneration promoting composition in preparation of a medicine for treating diabetic foot ulcer. The detoxifying and tissue regeneration promoting composition is prepared from the following raw materials in parts by weight: 60-100 parts of radix arnebiae seu lithospermi, 60-100 parts of radix angelicae sinensis, 20-60 parts of radix angelicae, 20-60 parts of liquorice root, 10-40 parts of frankincense and 10-50 parts of dried alum.

The invention relates to the technical field of traditional Chinese medicine compositions. The invention provides a traditional Chinese medicine composition for treating rheumatism and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 8-12 parts of safflower, 8-12 parts of selaginella tamariscina, 8-12 parts of radix saposhnikoviae, 13-17 parts of rhizoma atractylodis, 18-22 parts of garden balsam stem, 18-22 parts of lycopodium clavatum, 8-12 parts of cassia twig, 2-4 parts of asarum, 13-17 parts of gentiana macrophylla, 8-12 parts of ligusticum wallichii, 13-17 parts of pawpaw, 8-12 parts of frankincense, 8-12 parts of myrrh, 8-12 parts of radix aconiti carmichaeli, 8-12 parts of rhizoma cibotii, 8-12 parts of notopterygium root and 4-6 parts of scorpion. The traditional Chinese medicine composition can effectively treat rheumatism, and is remarkable in effect and rapid in pain relieving.