143 results about "Breast nodules" patented technology

The invention relates to a sticking plaster used for treating lumps in breast, and is prepared by the following raw materials: radix bupleuri, nutgra galingale rhizome, bitter orange, szechwan chinaberry fruit, cistanche salsa, barrenwort, common burreed rhizome, rhizoma zedoariae, pangolin, szechuan lovage rhizome, radix curcumae, frankincense, myrrh, rhizoma corydalis, nux vomica, dragon's blood, cowherb seed, safflower, peach seed, euphorbia kansui, snakegourd fruit, gleditsia sinensis sting, airpotato yam, seaweed, raw rhizoma arisaematis, raw tuber pinellia, white mustard seed, oyster, portulaca grandiflora hook, iphigenia indica, paridin, oldenlandia diffusa, dandelion, red paeonia, Chinese goldthread, yellowcypress, rhubarb, raw szechuan aconite, raw wild aconite, datura flower, cinnamon, white pepper, asarum, angelica dahurica, scorpion and centipede. With reasonable compatibility, the invention has the functions of soothing liver, regulating qi, activating blood circulation, removing stasis, softening hard lumps, dispelling nodes, clearing away heat and toxic material, releasing swelling and stopping pain. The invention has wide medicinal odour, large dosage, strong efficacy and definite curative effect. Patients have no pain for application, and the cost is low; the effective rate of treatment is 98.62 percent, and the cure rate can reach 96.77 percent; the application of the sticking plaster can effectively prevent the occurrence of breast carcinoma.

The invention relates to the technical field of medical image processing, and aims to provide a dynamic ultrasonic breast nodule real-time segmentation and recognition method based on deep learning. The method comprises the following steps: collecting ultrasonic mammary gland images and videos with nodules and case data with operative pathology results, constructing a data set, constructing a static image nodule segmentation network, and training the static image nodule segmentation model on an original image; predicting an intermediate frame nodule probability by using an LSTM layer, constructing a video dynamic segmentation network, and training a dynamic segmentation model; constructing a benign and malignant identification network structure by using a basic network, and training a benign and malignant identification model; and outputting nodule position information in real time, using the benign and malignant recognition model for recognizing benign and malignant nodules of each frame, and outputting the number of output nodules and the comprehensive benign and malignant probability after examination is finished. Information incompleteness of a single image can be avoided, error detection is reduced, missing small nodules are reduced, and the nodule benign and malignant identification accuracy is improved.

The invention discloses a breast nodule detection method and system based on ultrasonic medicine. The method comprises the steps of obtaining breast ultrasonic video data, carrying out the preprocessing, carrying out training on the preprocessed data through a transfer learning method, building a breast nodule detection model, inputting to-be-tested video data into the breast nodule detection model, and obtaining a result. The breast nodule detection method and system based on ultrasonic medicine aim to establish a precise method for judging benign and malignant breast tumors and carrying outpathological typing by taking ultrasonic breast video image examination as a main means, and solve the difficult clinical problem that dynamic identification and identification of breast tumors are difficult. The establishment of the highly accurate breast tumor qualitative system is of great clinical significance to the diagnosis and treatment of breast tumor patients.

The invention discloses a Chinese traditional medicine combination for treating mastosis and a preparing method. The Chinese traditional medicine combination is prepared by dandelion, bupleurum root, angelica, nutagrass flatsedge rhizome (vinegar bake), radix salviae miltiorrhizae, root of herbaceous peony (fried), seed of cowherb, red peony root, bighead atractylodes rhizome (fried). The Chinese traditional medicine combination has excellent function of clearing the liver and enriching the blood, regulating vital energy and dispelling melancholy without toxicity and side-effect and is adaptable to hypochondriac distress and pain, breast nodule and tenderness, breast pain before menstruation, abnormal menstruation and hyperplasia of mammary glands. Compared with the prior art, the invention has good prescription, high bioavailability and remarkable therapeutic effects.

The invention discloses a traditional Chinese medicine for treating liver depression and blood stasis syndrome type breast nodule diseases. The traditional Chinese medicine for treating the liver depression and blood stasis syndrome type breast nodule diseases is characterized by being prepared from the following medicinal materials in parts by weight: 10 parts of Chinese thorowax root, 20 parts of rhizoma atractylodis macrocephalae, 30 parts of Indian Buead, 10 parts of Chinese angelica, 30 parts of white paeony root, 10 parts of peach kernel, 10 parts of rheum officinale, 30 parts of leonurus, 20 parts of rhizoma cyperi, 30 parts of semen coicis, 30 parts of selfheal, 12 parts of scrophularia ningpoensis, 15 parts of keel, 30 parts of oyster, 15 parts of tangerine seed, 15 parts of lychee seed, 6 parts of cowherb seed, 6 parts of liquorice, 10 parts of stir-fried gardenia and 2 parts of pangolin. The traditional Chinese medicine prepared according to the formula has the effects of soothing liver, relieving depression, removing blood stasis, reducing phlegm, softening hard lumps, dispelling nodes and regulating thoroughfare and conception vessels, can effectively treat breast nodule diseases, can also obviously improve the concomitant symptoms of a patient, does not have obvious side effect, and is safe and effective in treatment of the breast nodule diseases. The use of the traditional Chinese medicine on 82 patients in the past three years shows that the effective rate reaches 90.2% and the diseases cannot be relapsed after being cured.

The invention relates to a medical image processing technology, and aims to provide a method for identifying benign and malignant breast nodules based on a shear wave elastic diagram of deep learning.The method comprises the following steps: collecting case data of an ultrasonic mammary gland common B-ultrasonic image and a shear wave elastic image with nodules, and constructing a benign and malignant classification data set according to a pathological result; selecting a basic network structure, replacing part of the convolution layer with a rotary pooling convolution layer, and constructinga benign and malignant identification network structure; adding nodule mask information to network input, performing data enhancement on a training set, and using separable Dropout calculation in thetraining process to improve the generalization ability of the model; and inputting a test image, carrying out multi-image-block and multi-model test to evaluate model performance, and carrying out breast nodule benign and malignant judgment on the image. Compared with a method for identifying benign and malignant parts by using a common B-ultrasonic image, the method can improve the benign and malignant diagnosis accuracy. According to the method, the rotation invariance can be learned, and the model recognition accuracy can be improved under the condition that the network calculation complexity is not increased.

The invention relates to an external application Chinese medicinal composition for treating cystic hyperplasia of breast. The external application Chinese medicinal composition comprises the following bulk pharmaceuticals in parts by weight: 20-2,000 parts of garden balsam stem, 4-400 parts of frankincense, 4-400 parts of myrrh, 5-480 parts of indian iphigenia bulb, 4-400 parts of cowherb seed, 4-400 parts of pangolin, 6-600 parts of honeycomb, 4-400 parts of green tangerine peel, 6-600 parts of tangerine seed and 2-120 parts of borneol. The compatibility of a Chinese medicinal formula adopted in the invention is consistent with the principle of syndrome differentiation and treatment of cystic hyperplasia of breast. In a treatment method, the external application Chinese medicinal composition is mainly used for dispersing the depressed liver-energy, relieving pain, invigorating blood circulation, activating the channels and eliminating stagnation. According to breast nodule powder in a prescription, and the treatment principle of intramammary nodules includes promoting qi circulation, removing obstruction, reducing phlegm, resolving masses, dissolving stasis and relieving pain, and is just matched with the pathogenesis of intramammary nodules. Through external application, the medicament can permeates into a human body through pores, plays a role in clearing and activating thechannels and collaterals, and directly reaches an affected site, so that a treatment effect is achieved.

The present invention relates to a kind of medicine composition prepared with natural plant medicine materials and with the functions of resisting inflammation, eliminating swelling, softening mass and dissipating blood stasis. The medicine composition is prepared with seven kinds of Chinese medicinal materials, including leaatherleaf mahonia stem, thin evodia, motherwort, spatholobus stem, smilax glabra rhizome and forsythia in certain proportion. It is used in treating energy stagnation and blood stasis caused breast nodules, mastoproliferation, ovary cyst, etc.

The invention discloses a externally used plaster for treating galactophore diseases and method for its preparation, wherein the plaster is prepared from zedoary 153-187, curcuma longa 122-150, garden balsam seed 122-150, root of muskroot-like semiaqilegia 91.8-112.2, momordica seed 30.6-37.4, dahurian angelica root 45.9-56.1 through disintegrating into mesh fines, preparing alcohol extract grease, heating honey and stirring.

The present invention discloses breast nodule eliminating bolus of and its preparation. The present invention relates to preparation form innovation on the basis of available tablet, and the medicine has the advantages of fast release speed, high bioavailability, less irritation, etc. The medicine has the functions of dispersing the stagnated liver energy, regulating vital energy, promoting blood circulation and removing blood stasis, and has obvious curative effect on vital energy stagnation and blood stasis caused hyperplasia of mammary glands and breast swelling and pain.

The invention discloses a chest protector essential oil stock solution and an inductive biologic magnetic chest protector film, and preparation methods thereof. The chest protector essential oil stock solution comprises 90-98wt% of wheat germ oil, 1-5wt% of St.John's Wort Oil, 0.1-3wt% of Pelargonium asperum essential oil and 0.1-2wt% of Valeriana officinalis essential oil. The inductive biologic magnetic chest protector film is obtained by uniformly sprinkling the chest protector essential oil stock solution on an inductive biologic magnetic film selected as a film substrate. The chest protector essential oil stock solution directly contacts with the surface of breasts when the chest protector essential oil is uniformly distributed on the surface of the chest film substrate, so the chest protector essential oil can rapidly penetrate the breasts and is fully absorbed by breast tissues, thereby the functions of effective components in the essential oil stock solution are fully performed, and the use effect of the chest protector film is improved. Clinic tests show that the inductive biologic magnetic chest protector film has good auxiliary physiotherapy effects on breast nodules and hyperplasia, has very good mammary areola weakening and pigmentation improving efficacies, and makes chest skins compact and elastic.

The invention relates to the field of medical image technology, and particularly to a breast nodules auxiliary diagnosis method based on DSSD and a system. The system comprises a breast image workstation, a breast cloud diagnosis system and a breast diagnosis mobile terminal. The breast image workstation performs breast image acquisition. The breast cloud diagnosis system comprise training set anda testing set preprocessing, marking and neural network discriminating, wherein the training set and the testing set preprocessing comprises multi-scale image de-noising and enhancing. The method comprises the steps of acquiring a breast graph by the breast image workstation, performing discriminating through mainly using a DSSD neural network, and finally transmitting a result which is obtainedthrough processing of the breast cloud diagnosis system to the breast diagnosis mobile terminal. According to the method and the system, a computer-aided diagnosis (CAD) system based on deep learningis developed for aiming at the field of the medical image (unnatural image), thereby supplying a second opinion for diagnosis to a radiology department doctor, and more effectively assisting the doctor in performing diagnosis.

The invention discloses a traditional Chinese medicine for treating mastopathy. The components of the traditional Chinese medicine comprise, by weight, 9-11 parts of pangolin, 9-11 parts of leech, 13-17 parts of Chinese angelica, 13-17 parts of Ligusticum wallichii, 9-11 parts of safflower, 14-16 parts of Rhizoma Sparganii, 13-16 parts of Rhizoma Curcumae, 27-33 parts of dragon bone, 17-33 parts of oyster, 13-17 parts of Peach Seed, 13-17 parts of Boswellia carteri, 13-17 parts of myrrh, 14-16 parts of Rhizoma Anemarrhenae, 8-12 parts of Pinellia Tuber, 13-17 parts of Combined Spicebush Root, 14-16 parts of Salvia miltiorrhiza, 9-11 parts of Cortex Moutan and 14-16 parts of Fructus Evodiae. The invention also discloses a preparation method of the traditional Chinese medicine. The traditional Chinese medicine follows a pain relieving-breast nodule eliminating-restoring-conditioning treatment principle, is used for simple mammary epithelial proliferation, cystic mammary epithelial proliferation and chronic mastitis, and has the advantages of fast effectiveness, no recurrence, no substantial side effects, and good curative effects on mammary fibroadenoma and the mammary cancer.

The invention relates to a breast lump resolving plaster and a preparation method thereof. The breast lump resolving plaster is composed of a plaster matrix and a Chinese medicinal composition in a weight ratio of 8: (1.5-2.5), wherein the Chinese medicinal composition is composed of the following raw materials in parts by weight: 3-5 parts of bupleurum, 3-5 parts of frankincense, 3-5 parts of myrrh, 3-5 parts of Szechuan lovage rhizome, 3-5 parts of curcuma, 3-5 parts of white peony root, 3-5 parts of fritillary bulb, 3-5 parts of pangolin, 0-5 parts of corydalis tuber, 0-5 parts of salviae miltiorrhizae, 0-5 parts of safflower, 0-5 parts of self-heal, 0-5 parts of Szechwan chinaberry fruit and 0-0.012 part of musk. The breast lump resolving plaster and the preparation method thereof have the advantages that the plaster is simple in ingredients but remarkable in effect and can treat various breast nodules, active ingredients of the plaster can be directly delivered to the interior of mammary tissues and completely absorbed, the matrix does no have stimulus at all, and the acceptability of patients is strong.

The invention discloses a traditional Chinese medicine patch for treating mammary gland diseases and promoting firmness of mammary glands. The traditional Chinese medicine patch comprises raw materials in percentage as follows: 80%-95% of hydrogel, 0-0.5% of liquid Germall plus BP, 0-0.5% of peony essential oil, 0-0.5% of almond essential oil, 0-1% of safflower and 2.5%-17.5% of a traditional Chinese auxiliary material. The Chinese herbal medicines are extracted and prepared to form slow-release microparticles, dissolved in the hydrogel and induced into skin layer by layer, the medicines are induced and permeate into the skin continuously, and the functions of regulation, treatment and relieving of breast nodules and hyperplasia of the mammy glands are realized. The stomach channel of foot-yangming and the spleen channel of foot-taiyin which cover the meridians of the mammary glands are smooth under the treatment and regulation functions of the Chinese herbal medicines on the mammary glands; the mammary glands are full and plump, cell regeneration is effectively stimulated, and the function of promotion of firmness of the mammary glands is realized. The flow speed of blood around nipples and mammary areola is increased by the permeating medicines, the melanin metabolism capacity is improved, and the function of reducing pigmentation of the nipples and the mammary areola is realized.

The present invention discloses breast nodule treating bolus of and its preparation. The present invention relates to preparation form innovation on the basis of available capsule, and the medicine has the advantages of fast release speed, high bioavailability, less irritation, etc. The medicine has the functions of dispersing the stagnated liver energy, alleviating mental depression, promoting blood circulation, clearing away toxic matter, softening the dry feces and dissipating mass, and has obvious curative effect on hyperplasia of mammary glands, mastitis, etc.

The invention provides a traditional Chinese medicine composition for treating Chong and Conception Vessel disharmony type breast nodules, comprises the following components by weight: 7-11 parts of rhizoma curculiginis, 8-12 parts of epimeddium, 7-11 parts of Chinese angelica, 8-12 parts of white peony root, 8-12 parts of anemarrhena, 7-11 parts of phellodendron, 9-15 parts of Radix Rehmanniae Preparata, 5-7 parts of Ligusticum wallichii, 7-11 parts of radix bupleuri, 7-11 parts of curcuma tuber, 7-11 parts of morinda officinalis, 7-11 parts of Cornus officinalis, and 9-15 parts of szechwan Chinaberry fruit. Compared with the prior art, the traditional Chinese medicine composition in the invention is used for treating internal pathogenic factors of Chong and Conception Vessel disharmony type breast nodules based on symptoms, and has advantages of fast curative effect, low cost, no toxic or side effect and substantial effect, and the traditional Chinese medicine composition is used for treating both symptoms and root causes.

The invention discloses a preparation method of a liquid for internally eliminating breast nodules. In the preparation method, a membrane pressure filtration and circulating extraction and separation integrated technology is utilized to replace the existing decocting methods for extracting the active ingredients of the prescription crude drugs, thereby simplifying process route, shortening production period, saving energy, favoring environmental protection and waste residue utilization and greatly improving the recovery rate of the active ingredients; and in a preparation step, direct filtration with an ultrafiltration membrane is utilized to replace a filtering method of standing firstly and then taking supernatant, the quality problem that the finished produce cannot meet the related specification of mixtures because of easy generation of precipitates which are hardly dissolved after being shaken can be solved thoroughly, and the production period can be shortened further.

The invention relates to a medical care auxiliary appliance, and specifically relates to a bio-electrical paste for hyperplasia of mammary glands, breast nodule and lumbar disc herniation. The bio-electrical paste is applied to adjuvant therapy of hyperplasia of mammary glands, breast nodule and lumbar disc herniation. The bio-electrical paste comprises two conduction electrodes; a capacitor C or a resistor R is connected between the two conduction electrodes. The paste is applied to the focus to treat hyperplasia of mammary glands and lumbar disc herniation. According to the bio-electrical paste, the conduction electrodes are the metal electrodes manufactured from different materials; for a patient suffering from the hyperplasia of mammary glands, the paste works effectively after pasting for 6 hours once a day, and after one month of use, the effect is obvious, and the effective rate reaches 100%; therefore, the paste is beneficial for the adjuvant therapy of the patient suffering from the hyperplasia of mammary glands; for the patient suffering from lumbar disc herniation, the paste works effectively after pasting for 8 hours once a day, and after one month of use, the effect is obvious, and the effective rate reaches 100%; therefore, the paste is beneficial for the adjuvant therapy of the patient suffering from lumbar disc herniation.

The invention discloses a traditional Chinese medicinal preparation capable of diminishing swelling and removing stasis. The traditional Chinese medicinal preparation is prepared from the following raw materials in parts by weight: 60-100 parts of mirabilite, 60-100 parts of spica prunellae, 30-60 parts of rhizoma arisaematis, 30-50 parts of radix codonopsis, 10-20 parts of nidus vespae, 30-50 parts of roots and leaves of schefflera octophylla, and 30-60 parts of bulbus frityllariae cirrhosae. The traditional Chinese medicinal preparation capable of diminishing swelling and removing stasis hasthe obvious treating efficacies of diminishing swelling and removing stasis, the purpose of treating hyperplasia of mammary glands, breast nodule, mastadenoma, ovarian cyst, ovarioncus, myoma of uterus, thyrophyma, thyroid nodule, subcutaneous lipoma and the like through external use is achieved, the production and preparation costs of the medicinal preparation are also greatly reduced, in addition, the clinical safety is improved, the stability of the efficacies is guaranteed, the purposes that the obvious curative effects are obtained through short-term use and the popularization and application are benefited are achieved, and thus the use and treatment of patients are greatly benefited.

The invention discloses a medicine for treating hyperplasia of mammary glands, and particularly relates to a breast nodules-eliminating cataplasm and a preparation method thereof. The breast nodules-eliminating cataplasm is prepared from the following raw materials: dandelion, antler, kelp, radices trichosanthis, caulis spatholobi, pseudo-ginseng, radix paeoniae rubra, seaweed, uniflower swisscentaury root, elecampane, radix scrophulariae, moutan bark, selfheal, fructus forsythiae, safflower, sodium polyacrylate, chondroitin sulfate, polyvinylpyrrolidone, aluminum dihydroxyaminoacetate, docosahexaenoic acid, glycerol, tartaric acid and sodium carboxymethylcellulose. The cataplasm provided by the invention has the characteristics of large drug loading capacity, strong moisture retention, good compatibility with skin, accurate dosage, repeated uncovering and pasting, and drug administration termination at any time, and has the advantages of high stability and safety, high patient use comfort, fast onset of action, and long drug effect lasting time.

A Chinese medicine 'Rupi Anxiao particles' for treating breast nodule, lobuleplasia of breast, ovarian cyst and hysteromyoma is proporionatlly prepared from 6 Chinese-medicinal materials including mahonia stem, thin evodia, motherwort, China root, etc. Its preparing process is also disclosed.

The invention relates to the field of biomedical diagnosis, in particular to application of exosome mRNA in breast disease diagnosis. By use of the exosome mRNA, benign and malignant identification can be carried out on breast nodule patients, mammary cancer and other malignant tumors can be effectively distinguished to realize accurate diagnosis of the mammary cancer, and the treatment effect ofpatients can be monitored. It is found for the first time that the exosome mRNA marker can be used for diagnosing breast diseases.

The invention discloses a Chinese medicine external application for treating hyperplasia of mammary glands. The hyperplasia of mammary glands belongs to the category of breast nodules in traditional Chinese medicine, and is mainly found in young and middle-aged women, and emotion depression, disorder of liver, qi and blood stagnation, ischogalactia and mass formed by accumulation are pathogenesis. For this purpose, traditional Chinese medicine fermented soybeans, neat philippine violet herb, croton laevigatus vahl, sawgrass, viola serpens wall, trifoliate orange, chachi citrus leaves, scutellaria indica, pericarpium canavaliae, radix curcumae, roses and radix chloranthi serrate with effects of smoothing live-qi stagnation, removing stasis and dispersing blood stasis are selected and prepared into the external application. The clinical tests show that the total effective rate reaches 97.5%.

The present invention discloses breast nodule eliminating bolus of and its preparation. The present invention relates to preparation form innovation on the basis of available capsule, and the medicine has the advantages of fast release speed, high bioavailability, less irritation, etc. The medicine has the functions of dispersing the stagnated liver energy, regulating vital energy, softening the dry feces, dissipating mass, removing blood stasis and relieving pain, and has obvious curative effect on vital energy stagnation and blood stasis caused hyperplasia of mammary gland lobules, etc.

The invention discloses a mammary gland plaster for far-infrared physiotherapy, and a preparation method thereof. The mammary gland plaster comprises, by weight, 60-80% of sharp and mild type functional drug mixtures, 5-12% of slippery functional drug mixtures, 10-15% of compatible functional drug mixtures and 6-11% of special functional drug mixtures. The mammary gland plaster can effectively treat lobular hyperplasia of mammary glands, breast nodules, fibroid tumors, lumps, mastitis, dysmenorrhea, myomas and coldness of the uteruses, lymphadenectasis and other symptoms of the lymphatic system; by a method for external application of traditional Chinese medicine, the mammary gland plaster is safe, free from side effects, and has low sensitization effect, high penetrating power and quick action; patients have different conditioning feelings, such as feeling cold, hot, sore, itching and pricking, according to different causes.

The invention discloses a traditional Chinese medicinal inflammation-removing decoction for treating acute mastitis. The acute mastitis is called as breast nodule by herbalist doctors and is caused by blocked and unsmooth breast channels, qi stagnation and blood stasis, which are caused by milk stasis, unsmooth temperament and interest and liver-qi stasis. The principle is relieving liver for smoothing Qi, detoxifying and dissipating stagnation, and promoting blood circulation and removing stasis. Therefore, the following materials: achyranthes bidentata, leonurus japonicus, ligusticum wallichi, rhizoma corydalis, curcuma aromatica, hematoxylon, red paeony root, fructus forsythiae, cassia twig and immature tangerine, are selected. The materials are scientifically prepared into the decoction in a preparation room of our hospital. Clinical tests show that the effect rate of the decoction is up to 96.7 percent, the side effect is low, and the treatment cost is low.

The invention discloses an ultrasonic health care bra. The ultrasonic health care bra comprises a front bandage, a rear bandage and two cups, wherein the two cups are fixedly connected through the front bandage; the two ends of the rear bandage are fixedly connected with the two cups respectively; a control mechanism is arranged on the rear bandage; the control mechanism comprises a control assembly, a control unit, a communication unit, a pressure sensing unit, an inflation and deflation unit and a power supply unit; the power supply unit is used for supplying power to the control mechanism;the pressure sensing unit is used for acquiring pressure data of the back; each cup is of a double-layer structure; and a flexible bracket, an ultrasonic generator control circuit, an energy convertergroup and a core energy converter are arranged on the first layer. According to the ultrasonic health care bra disclosed by the invention, a built-in airbag and a sensor are combined, so that the ultrasonic health care bra can be adaptive to breasts with various sizes and ultrasonic massaging can be conveniently carried out on a user when the user needs, and furthermore, the health level of mammary glands is improved; and the ultrasonic health care bra has very good effects of alleviating mammary gland swelling pain in a menstrual period and preventing hyperplasia of mammary nodules.

The present invention discloses instant porridge recovering intestinal flora balance of patients with breast nodules and a preparation method thereof. A recipe of the instant porridge comprises the following raw materials: 4-6 parts of hypsizygus marmoreus, 4-6 parts of chrysanthemum, 4-6 parts of ecklonia kurome, 4-6 parts of poria cocos, 2-3 parts of lucid ganoderma, 2-3 parts of dandelion, 2-3 parts of grifola frondosa, 2-3 parts of hericium erinaceus, 2-3 parts of cordyceps militaris, 2-3 parts of agaricus blazei, 30-40 parts of wheat bran, 70-80 parts of corn, and 30-40 parts of hypsizygus marmoreus crude fibers. The instant porridge can regulate intestinal flora and can effectively reduce the breast nodules.