61 results about "Breast nodules" patented technology

The invention provides a breast nodule three-dimensional reconstruction method and system, and the method comprises the steps: obtaining a plurality of frames of breast ultrasonic images, and carrying out the preprocessing, including filtering and denoising processing and image enhancement processing; performing feature extraction on the image by adopting a lightweight convolutional neural network structure to obtain a feature map; carrying out segmentation processing on the feature map by utilizing a segmentation module; sGBM stereo matching operation is carried out on the segmented images, parallax information between the images is obtained, adaptive curve correction is carried out on the parallax information, and three-dimensional reconstruction of breast nodules is realized; and establishing a dynamic calibration mechanism and designing an adaptive adjustment algorithm to continuously optimize and calibrate the three-dimensional reconstruction operation. Through image preprocessing, algorithm optimization, dynamic calibration and adaptive adjustment, the problems that in the prior art, the image quality is high in requirement and prone to being affected, the computing resource consumption is large, and the three-dimensional reconstruction precision is low are solved.

A breast tumor marker based on a serum protein, used for carrying out serum measurement on suspected breast tumor patients, and effectively distinguishing healthy people, breast nodule patients, and breast cancer patients. A serum protein spectrum classifier has, in an independent verification queue, an accuracy of 0.87, a precision of 0.93, a recall of 0.82, and an F1-score of 0.86. The area under the ROC curve for benign nodule patients is 0.96, the area under the ROC curve for breast cancer patients is 0.96, and the area under the ROC curve for healthy people is 0.96. The marker has high accuracy and good specificity, and has a good application prospect in clinical diagnosis of breast lesions.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating nodules and a preparation method thereof. The traditional Chinese medicine composition is prepared from radix bupleuri, angelica sinensis, radix paeoniae alba, poria cocos, roasted rhizoma atractylodis macrocephalae, mint, salvia chinensis, spina gleditsiae, bulbus fritillariae thunbergii, selfheal, seaweed, kelp, pericarpium citri reticulatae viride, trichosanthes kirilowii maxim, rhizoma pleionis, oriental wormwood and malt. Through reasonable compatibility, the monarch drug, the ministerial drug, the adjuvant drug and the conductant drug cooperate properly, so that the overall efficacy of the prescription is more remarkable, and the prescription has a remarkable effect on treating thyroid nodules and breast nodules.

Disclosed in the present invention is a physician-interpretable ultrasound-based breast cancer pathological subtype detection system, comprising: a segmentation module, which uses a U-Net network and incorporates a foreground optimization network to segment a breast and a nodule; a texture channel, which extracts a texture channel feature; an edge channel, which extracts boundary information; a position channel, which extracts position information, so as to quantize the overall relationship between the nodule and the boundary information of the breast to extract a breast nodule growth position feature; a shape channel, which calculates an edge aspect ratio on the basis of a segmented nodule region, so as to obtain a predicted interval value as a shape channel feature; an echo channel, which calculates the echo difference between the interior and exterior of the nodule to serve as an echo channel feature value; and a joint prediction module, which uses a multinomial logistic regression model to classify and predict breast cancer pathological subtypes on the basis of output features of the texture channel, the edge channel, the echo channel, the shape channel and the position channel. An artificial intelligence diagnosis tool that is interpretable to physicians is built, thereby providing an automated theoretical basis for clinical diagnosis and decision-making.

The invention relates to the technical field of mastopathy medicines, and discloses a traditional Chinese medicine patch for treating breast nodules and a preparation process thereof. The traditional Chinese medicine patch comprises the following raw materials: safflower, pollen typhae, caulis spatholobi, angelica sinensis, trogopterus dung, lumbricus, gastrodia elata, pseudo-ginseng, cassia twig, thunberg fritillary bulb, frankincense, endothelium corneum gigeriae galli, rhizoma atractylodis, platycodon grandiflorum, curcuma zedoary, radix semiaquilegiae, radix bupleuri and salvia miltiorrhiza. Through reasonable compatibility of the raw materials and effective extraction of the active ingredients of the traditional Chinese medicines, the effects of the raw materials can be maximized, all the components have a synergistic effect, the permeability is high, the efficacy is lasting, and the traditional Chinese medicine preparation has the effects of soothing liver and regulating qi, promoting blood circulation to remove meridian obstruction, eliminating stasis and dissipating binds, clearing heat and dispelling wind, and nourishing yin and relieving pain; the traditional Chinese medicine composition has obvious curative effects on various breast diseases such as breast nodules, hyperplasia of mammary glands, pains, lumps and the like, the nodules disappear, and the mammary glands basically have no pains and uncomfortable symptoms.

The invention provides a mammary nodule malignant transformation risk prediction system and method, a terminal, a medium and a product. The system comprises a multi-source data acquisition module used for acquiring multi-source mammary gland related medical data of a target mammary nodule patient and preprocessing the multi-source mammary gland related medical data; the key prediction feature screening module is used for carrying out key feature screening on the preprocessed data to obtain mammary gland key prediction feature data; and the prediction module is used for inputting the breast key feature data into a pre-constructed breast nodule risk prediction model to obtain a corresponding breast nodule malignant transformation risk prediction result. According to the method, the related medical data of the multi-source mammary gland is integrated, and key feature screening and the mammary nodule risk prediction model are combined, so that the limitation of traditional single-dimensional evaluation is broken through, and early warning of malignant transformation of the mammary nodule is realized.

The invention provides a method, a system, equipment and a program product for predicting benign and malignant breast nodules, and the method comprises the steps: collecting an ultrasonic image of a to-be-detected breast nodule; based on the ultrasonic image, a gaze graph generator of the attention guiding module generates a virtual gaze graph corresponding to the ultrasonic image; based on the ultrasonic image and the virtual staring image, a staring image classifier of the attention guiding module outputs the malignant probability of the breast nodule to be detected corresponding to the virtual staring image; wherein the staring image generator and the staring image classifier are obtained based on training of the training ultrasonic image and the real staring image; the real staring map comprises attention information of the expert during ultrasonic diagnosis; and based on the ultrasonic image, the uncertainty calculation module generates an evidence vector corresponding to the ultrasonic image, and generates credibility corresponding to the malignancy probability based on the evidence vector. The interpretability of benign and malignant prediction of breast nodules can be improved, and automation bias is reduced.

The invention discloses a medicinal and edible traditional Chinese medicine composition for treating breast nodules and a preparation method thereof, and belongs to the technical field of biology and new medicine. The traditional Chinese medicine composition for treating breast nodules comprises dandelion, kelp, ginseng, mulberry, astragalus membranaceus, lucid ganoderma, brassica juncea, oyster, perilla seeds, platycodon grandiflorum, fingered citron, pericarpium citri reticulatae and the like. In addition, the invention also provides a preparation method of the traditional Chinese medicine composition, which comprises the following steps: pouring the lucid ganoderma, the dried orange peel, the peach kernel, the Chinese angelica and the like together with soaking water into a pot, decocting, adding the soaked dandelion, kelp and the like into the pot, continuously decocting, filtering and collecting a first decoction and decoction dregs, adding a proper amount of water into the decoction dregs again, and filtering to obtain the traditional Chinese medicine composition. Continuing to boil and decoct, collecting a second decoction, and combining the first decoction and the second decoction to obtain the traditional Chinese medicine composition. The traditional Chinese medicine composition for treating breast nodules, provided by the invention, has a remarkable effect of treating breast nodules under the synergistic effect of all the components.

The invention discloses a breast cancer prevention and treatment method and system based on ultrasonic artificial intelligence and 5G internet of medicine, and is applied to the technical field of breast cancer prevention and treatment. The method comprises the following steps: formulating a breast cancer risk factor questionnaire, performing breast cancer related risk factor investigation on a research object, and establishing a risk prediction model; acquiring mammary gland color Doppler ultrasound image data of the research object; a breast nodule screening system based on the ultrasonic artificial intelligence technology is established, the breast nodule screening system conducts artificial intelligence technology analysis on the breast color ultrasound image data, and a preliminary diagnosis result is given; and obtaining a breast nodule screening rate, a breast cancer early cancer screening rate and an early diagnosis rate according to an analysis result of the breast nodule screening system. The artificial intelligence ultrasonic inspection is more convenient, rapid in input, high in inspection speed and capable of adapting to various complex environments.

The invention discloses nucleus eliminating granules which are prepared by the following steps: adding water into 12 medicinal materials, namely selfheal, oyster, kelp, beautiful sweetgum fruit, fructus aurantii, cowherb seed, salvia miltiorrhiza, curcuma zedoary, ligusticum wallichii, white paeony root, corydalis tuber and radix bupleuri, heating, extracting, filtering, concentrating and drying to obtain medicinal powder; and sieving, adding auxiliary materials, adding a wetting agent, preparing a soft material, granulating, and drying to obtain the kernel eliminating granules. The invention further discloses a preparation method of the nucleus eliminating particles, a thin-layer chromatography identification and content determination method and application of the nucleus eliminating particles. According to the invention, the nucleus-eliminating mixture is developed into the nucleus-eliminating particles, the forming rate, the dissolution rate, the moisture absorption rate, the fluidity and the like of the nucleus-eliminating particles all meet the requirements of Chinese Pharmacopoeia, and the stability experiment result shows that the product stability is good; the curative effect of the nucleus eliminating granules on breast pain, breast nodules, hyperplasia of mammary glands and breast diseases can be achieved; doctors realize accurate medication under treatment based on syndrome differentiation, and the flexibility of adjusting prescriptions along with symptoms is guaranteed; on the other hand, more convenient carrying and taking experience can be provided for the patient.

The utility model discloses a wearable breast electrical impedance information acquisition sensor, and belongs to the field of medical detection sensors. The technical key points are that elastic plastic fixing plates are fixedly arranged on the inner layer and the outer layer of the front-side carrier, and a group of electrode rings are arranged on each of the left-front-side carrier and the right-front-side carrier; the group of electrode rings comprises 16 electrode rings, the 16 electrode rings are divided into inner rings and outer rings, the electrode rings of the inner rings and the electrode rings of the outer rings are concentrically arranged, and the electrode rings of the inner rings and the electrode rings of the outer rings are uniformly spaced. According to the wearable breast electrical impedance information acquisition sensor, breast nodules can be conveniently detected, and the detection efficiency and accuracy can be improved.

The application discloses a traditional Chinese medicine composition and a preparation method and application thereof; active ingredients of the traditional Chinese medicine composition include rose, bergamot, cydonia, poria cocos, Chinese yam, gordon euryale seed, coix seed, sea buckthorn, malt, chicken gizzard, angelica, longan, medlar, donkey-hide gelatin, mulberry, kelp, oyster, dandelion, dried tangerine or orange peel, platycladus, yellow mustard seed, peach kernel, saffron, radix astragali, American ginseng, raw sun-dried ginseng, dendrobium officinale, lily, ganoderma lucidum, jujube and mint; the traditional Chinese medicine composition is formed by the principle of monarch, minister, assistant and guide, forms a traditional Chinese medicine prescription of specific active ingredients, forms a herbal ointment that treats in all directions, has a remarkable curative effect on breast nodules, and has a good taste, is portable, and meets the long-term treatment requirements.

The invention relates to the field of computer vision, and discloses a construction and application method of a target detection model, a model, equipment and a medium, the construction scheme introduces an attention mechanism module and a residual module into a deep learning model, the attention mechanism module can better capture important features in a mammary gland image, and the residual module can better capture the important features in the mammary gland image. The breast nodules and the background are effectively distinguished, the residual module can relieve the gradient disappearance problem in the training process of the target detection model, and the learning ability of the model is enhanced. Therefore, according to the construction scheme of the application, the target detection model with better performance can be obtained by using the target detection model which introduces the attention mechanism module and the residual module into the mammary gland image training, and a more accurate detection result can be obtained when the model is used for detecting the mammary gland nodules in the mammary gland image.

The invention discloses a breast-dredging and stasis-removing health-care cream and a preparation method thereof. The breast-dredging and stasis-removing health-care cream is composed of active components such as a ranunculus ternatus alcohol extract, panax notoginseng saponins, radix bupleuri volatile oil and the like, and an emulsion matrix. Through targeted liposome modification and a temperature-sensitive slow release technology, efficient delivery of anti-hyperplasia components is realized, the cream has dual effects of reducing the volume and relieving pain on breast nodules, and the transdermal efficiency is improved by 210% compared with that of traditional cream.

The invention discloses a method for analyzing an action mechanism of a breast nodule removing tablet. The method comprises the following steps: identifying chemical components of the breast nodule removing tablets; predicting effective target spots of the chemical components based on network pharmacology, and predicting target spots of hyperplasia of mammary glands; and performing clustering analysis and other operations on the relative content of differential proteins in the mammary gland hyperplasia model before and after the breast nodule removing tablets are taken based on proteomics. According to the application, a method for integrating multi-dimensional data through a'chemical component-target network-omics technology 'is used for discussing the action mechanism of the breast nodule removing tablets, important proteins, metabolites or pathways are screened out, research targets are more easily locked, and the action mechanism of the traditional Chinese medicine compound breast nodule removing tablets is disclosed.

The invention relates to the field of medical image analysis and artificial intelligence, and discloses a mammary gland benign nodule follow-up visit data processing and nodule risk early warning method, which comprises the following steps of: obtaining gray-scale ultrasonic images and color Doppler blood flow images of a baseline and a plurality of follow-up visit time points; an improved U-Net model is adopted to automatically segment the nodule area, and morphological features and blood flow features are extracted; constructing a feature change rate matrix based on the percentage change rate of each time point feature relative to the baseline, quantifying a dynamic evolution trend in combination with a time decay weight matrix, and generating a dynamic malignant risk score by coupling patient age and breast cancer high risk factors; and further dynamically optimizing a risk judgment threshold value through a deep reinforcement learning model, dividing low, medium and high risk levels according to a comparison result of the score and the threshold value, and outputting differentiated clinical intervention suggestions. According to the invention, accurate and personalized early warning of the malignant risk of the breast benign nodule is realized, and intelligent support is provided for clinical follow-up decision.

The utility model relates to the technical field of mammary gland nursing appliances, and discloses a device convenient for positioning mammary gland nodules, which comprises two connecting blocks and two positioners, mounting blocks of which one ends are fixedly connected with the left side and the right side of the rear side connecting block respectively are arranged on the left side and the right side of the front side connecting block. According to the device facilitating breast nodule positioning, the device is arranged on the outer side of the chest of a patient, the device is fixed in front of the chest by rotating two first hand wheels, then the positions of two positioners can be adjusted by rotating two third hand wheels, the two positioners are aligned with two mammary glands respectively, and the mammary glands can be positioned conveniently. And finally, two second hand wheels are rotated to enable the two positioners to cover the outer sides of the two mammary glands respectively, so that installation of the positioners is completed, the positions of the positioners can be adjusted, then the purpose of being convenient for patients with different body types to use is achieved, and practicability is improved.

The invention discloses a mammary gland stasis removing patch and a preparation method, and relates to the technical field of mammary gland nodule nursing, in particular to the mammary gland stasis removing patch which comprises an adhesive patch body, a center patch body is attached to the middle of one side of the adhesive patch body, stasis removing ointment connected with the adhesive patch body is arranged on the periphery of a patch film, and a combined patch body is attached to the periphery of the adhesive patch body; the traditional Chinese medicine composition further comprises a ginger root extract, angelica sinensis, liquorice, safflower carthamus, pseudo-ginseng root, ligusticum wallichii, laurel, salvia miltiorrhiza, elecampane, radix curcumae, poncirus trifoliate, cowherb seed, leonurus, selfheal, turtle shell powder, corydalis tuber, menthol, cape jasmine, azelaone, rhizoma cyperi, borneol and seaweed. The mammary gland stasis removing patch can achieve the qi and blood conditioning effect on the mammary gland, has the effects of promoting blood circulation to remove blood stasis, dredging meridians and collaterals, improving smooth blood flow of the mammary gland, stimulating blood capillaries, increasing local blood circulation and promoting nutrient absorption, can promote blood circulation in the mammary gland to a certain extent, can indirectly improve the hematopoietic function, and can effectively treat the mammary gland. The effect of eliminating mammary glands can be realized after long-term use.

The present disclosure provides a breast nodule three-dimensional reconstruction method and system, the method comprising acquiring multiple frames of breast ultrasound images and preprocessing, the preprocessing comprising filtering denoising processing and image enhancement processing; a lightweight convolutional neural network structure is used to extract features from the images to obtain feature maps; a segmentation module is used to segment the feature maps; SGBM stereo matching operation is performed on the segmented images to obtain disparity information between the images, and the disparity information is adaptively corrected to realize three-dimensional reconstruction of the breast nodule; a dynamic calibration mechanism is established and an adaptive adjustment algorithm is designed to continuously optimize and calibrate the three-dimensional reconstruction operation. Through image preprocessing, optimization algorithm, dynamic calibration and adaptive adjustment, the present disclosure overcomes the problems of high image quality requirement, susceptibility to influence, large calculation resource consumption and low three-dimensional reconstruction precision in the prior art.

The invention discloses an ointment composition for conditioning mammary glands and a preparation method of the ointment composition. The composition is prepared from the following raw materials in parts by mass: 5 to 50 parts of spica prunellae, 5 to 50 parts of herba hedyotidis diffusae, 50 to 200 parts of rhizoma coptidis, 50 to 200 parts of radix scutellariae, 50 to 200 parts of cortex phellodendri, 50 to 200 parts of radix astragali seu hedysari, 10 to 200 parts of radix notoginseng, 10 to 200 parts of radix angelicae sinensis, 50 to 200 parts of silkworm larva, 50 to 200 parts of semen pharbitidis, 10 to 50 parts of white lime, 10 to 50 parts of talcum powder and the like. The solid raw materials are respectively ground and sieved into powder of more than 100 meshes, the powder is mixed according to the proportion of the formula, rosa roxburghii tratt, tribulus terrestris or agilawood seed oil is added into sesame oil, and the mixture is blended with glycerin or sesame oil to prepare the ointment. The traditional Chinese medicine composition is used for conditioning mammary glands, has the effects of softening hardness to dissipate stagnation, removing blood stasis and activating collaterals, is mild in medicine property, good in permeability and free of toxic and side effects, reaches 5 mm or above of mammary glands and interstices, and is used for daily mammary gland conditioning and maintenance and mammary gland disease prevention; the composition is suitable for mammary gland syndromes such as breast pain, breast lumps, milk discharge, hyperplasia of mammary glands, mammary gland fibroma, mammary cyst, mammary nodule, plasma cell mastitis and the like.

The invention provides a method for detecting circulating tumor cells through combination of Reigi staining and density gradient centrifugation. Comprising the following steps: (1) separating mononuclear cells from a blood sample; (2) performing Wright-Giemsa staining on the mononuclear cells obtained in the step (1); and (3) detecting the circulating tumor cells based on cell morphological characteristics. According to the method, the characteristics of the CTC cells can be observed more visually, and the method can be used for distinguishing benign breast nodules and malignant breast nodules, distinguishing stages of breast cancer and judging whether lymph node metastasis occurs or not.

The invention discloses a breast nodule detection method and system based on ultrasonic medicine, and the method comprises the steps: firstly obtaining breast ultrasonic video data, and carrying out the preprocessing of interception, zooming, sampling, screening, enhancement and the like; 18 layers of ResNet18 are adopted for feature extraction, a linear classification network and an attention selection network are combined, and a detection model is constructed through optimization of a cross entropy and a center loss function. The system is correspondingly provided with a feature extraction module, a linear classification module and the like. And finally, to-be-tested video data are input into the model, so that whether breast nodules exist or not and the result of benign and malignant nodules can be quickly obtained, and efficient and accurate assistance is provided for breast disease diagnosis.

The invention discloses a lactation dredging and stasis removing health-care liquid and a preparation method thereof. According to the preparation, through triple anti-hyperplasia core compatibility of selfheal, paris polyphylla and stigma croci and in combination with supercritical extraction and liposome encapsulation technologies, the concentration of crocin mammary tissue reaches 35.6 mu g / g. A vinegar-fried frankincense / myrrh nanocrystallization dispersion process is innovatively adopted, the problem of crystallization of resin components is solved, and no precipitate is generated in a 12-month accelerated test. Animal experiments prove that the volume of breast nodules can be reduced by 68.3%, and the traditional Chinese medicine composition is suitable for conditioning the sub-health state of female mammary glands.

The embodiments of the present invention provide a data detection method, a breast nodule detection model training method and an electronic device, which relate to the field of medical image processing technology. By inputting the ultrasound video to be detected into the trained breast nodule detection model, the detection frame information of each frame image of the ultrasound video to be detected is obtained, and each detection frame of each frame image is placed into multiple detection frame queues according to the position relationship. For each detection detection frame queue, it is determined whether the detection frame queue is a target detection frame queue that meets the first preset condition; if so, the position area corresponding to the detection frame in the target detection frame queue is marked as a breast nodule. In this way, the breast nodule detection model can be used to detect the ultrasound video, which can effectively reduce the false detection on the breast ultrasound video, and then the detection frame queue is used for screening and filtering, which can further reduce the false detection.

The invention discloses an ABUS-based nodule elastography detection method, device and equipment and a medium, and the method comprises the following steps: controlling a probe in an ABUS to carry out flat scanning along the surface of a mammary gland, obtaining a cross section two-dimensional ultrasonic image, and generating a coronal plane image; detecting and identifying the position of a focus in the coronal plane image, and tracing a cross section image sequence containing the focus; detecting and segmenting the focus, and determining the specific position of the focus in the sequence; a probe in the ABUS is controlled to move to the section position corresponding to the maximum section of the focus, the probe in the ABUS is controlled to apply pressure to the surface of the tissue, so that the tissue deforms, the displacement change of the tissue under the pressure effect is recorded, and a strain elasticity image is generated; and evaluating the relative hardness of the lesion area according to the strain elasticity image. The method has the advantages that the ABUS is used for achieving elastography of breast nodules, the relative hardness of a focus area is evaluated, the method can be used for breast lesion screening, positioning and tracking return visit, and the performance and application of ABUS equipment are expanded.

1. The name of this design product: Ultrasonic medical bed. 2. Purpose of this design product: used to treat breast nodules or tumors. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the key points of the design: Design 2 Stereoscopic Figure 2. 5. Designate Design 2 as the base design.

The application provides a traditional Chinese medicine external application composition for treating benign breast disease and preparation and application thereof, and belongs to the technical field of traditional Chinese medicine compositions, and is used for solving the problems of slow effect, large side effect and poor compliance of existing drugs for treating benign breast disease. The composition is composed of Tribulus terrestris 8-12 parts, Taraxacum officinale 8-12 parts, Pheretima 2-4 parts, Cornu Cervi 8-12 parts, mirabilite 16-24 parts, Pericarpium Citri Reticulatae Viride 10-14 parts, Swertia 8-12 parts, Ophiocordyceps sinensis 2-4 parts and borneol 1-3 parts. The medicinal materials are prepared into an external application powder, and the breast part is externally applied before sleep, and the application time is more than 6 hours each time. The application adopts external use and transdermal administration, has fast effect, no digestive tract stimulation and liver and kidney burden, is convenient to use, has high compliance, and is clinically verified to have exact curative effect on mastalgia, breast hyperplasia and benign breast nodules (including BI-RADS 3 and 4a nodules), has high safety, and is suitable for long-term conditioning of benign breast disease.

1. The name of the design product: ultrasonic medical trolley. 2. The use of the design product: for treating breast nodules or tumors. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 2.

The invention provides a breast ultrasound image segmentation method based on state propagation and edge prior and application thereof, and belongs to the field of medical image processing. In order to solve the problems of large noise interference, blurred focus boundary and insufficient long-range dependence modeling of a breast ultrasound image, the invention provides an SP-EdgeNet network, and a mixed feature enhancement module is constructed to replace traditional jump connection. The module captures a global context by using a state propagation path, explicitly enhances a geometric edge by using an edge prior path, and dynamically fuses through an adaptive mechanism. And meanwhile, a structure-semantic decoupling module and a cross-resolution collaborative mechanism are supplemented, so that deep purification and multi-scale alignment of the features are realized. According to the method, the problems of edge degradation and semantic gaps in feature transmission are effectively solved, and the breast nodule segmentation precision and boundary integrity are remarkably improved.