1074 results about "Ganoderma" patented technology

The invention relates to the field of lucid ganoderma processing equipment, and discloses lucid ganoderma slicing equipment which comprises a conveying belt, a portal frame is fixedly mounted on one side of the top of the conveying belt through a support, a movable frame is movably mounted on the lower side in the portal frame, and a variable-pitch shaft is movably mounted on the upper side in the movable frame; two guide rods are fixedly installed on the lower side of the interior of the movable frame, a plurality of movable blocks are evenly and movably installed on the outer diameters of the guide rods, blades are fixedly installed at the bottom ends of the movable blocks, and a sleeve is movably installed in the middle of the interior of the portal frame through two supporting rods; a rotating column is movably mounted at the inner top of the portal frame, the bottom end of the rotating column extends into the sleeve, and a bidirectional spiral groove is formed in the outer diameter of the rotating column. The ganoderma lucidum cutting device can efficiently clean ganoderma lucidum and automatically complete cutting, the blade can vibrate to prevent tearing and breaking during cutting, the slicing thickness is uniform and adjustable, the automation degree is high, and the finished product quality and the production efficiency are effectively improved.

The invention discloses a ganoderma lucidum cultivation environment multi-mode self-adaptive regulation and control method based on the Internet of Things, and relates to the technical field of ganoderma lucidum cultivation, and the method comprises the following specific steps: multi-source data collection: reasonably arranging an environment sensor and a biosensor in a ganoderma lucidum cultivation environment, and collecting environment data and biodata in real time, according to the method, various data in the lucid ganoderma cultivation environment are comprehensively collected, the environment factor coupling effect model is constructed in combination with a machine learning algorithm, comprehensive analysis and accurate regulation and control of the lucid ganoderma growth environment can be achieved, and the interaction relation between environment factors and the physiological state of lucid ganoderma are fully considered; the control decision is more scientific and reasonable, the growth speed and quality of the ganoderma lucidum are remarkably improved, the yield of the ganoderma lucidum is further improved, meanwhile, a biological feedback mechanism is introduced, the cultivation environment can adapt to the optimal growth requirement of the ganoderma lucidum in real time, and the cultivation accuracy and the intelligent level are further improved.

The invention relates to paclitaxel ganoderma lucidum spore oil self-nanoemulsion composite particles with ganoderma lucidum spores as a carrier and a preparation method of the paclitaxel ganoderma lucidum spore oil self-nanoemulsion composite particles, and belongs to the technical field of medicines. Pretreated Ganoderma lucidum spores (GLS) are obtained through process screening and serve as a drug carrier, and paclitaxel-loaded Ganoderma lucidum spore oil self-nanoemulsion (PGS) is loaded into the Ganoderma lucidum spores (GLS) to obtain paclitaxel-loaded composite particles (PGS (at) GLS). An in-vitro release curve shows that the PGS-atGLS has the characteristic of slow release after reaching the intestinal tract; in-vivo pharmacodynamic experiments show that PGS-atGLS can significantly inhibit development and metastasis of mouse colorectal cancer; tumor tissue slice immunofluorescence analysis shows that PGS-atGLS can effectively play a role in treating colon cancer. The paclitaxel self-nanoemulsion-loaded ganoderma lucidum spore composite particles synergistically promote cancer immune circulation by inducing immunogen cell death and immunoregulation, significantly improve the treatment effect of colon cancer, and have good biological safety.

The invention discloses a ganoderma lucidum fermentation liquid capable of improving the content of total triterpenes and immunity and a preparation method and application thereof, the preparation method comprises the following steps: heating a ganoderma lucidum liquid, and carrying out hot water extraction to obtain a ganoderma lucidum extracting liquid; heating the lucid ganoderma extracting solution to be boiled, after sterilization is finished, after the lucid ganoderma liquid is cooled, adding lactic acid bacteria powder in a specific proportion for fermentation to obtain lucid ganoderma fermentation liquid; and carrying out solid-liquid separation on the fermentation liquor to obtain fermentation supernate, and sterilizing the ganoderma lucidum fermentation liquor to obtain the sterilized ganoderma lucidum fermentation liquor. According to the preparation method disclosed by the invention, the content of total triterpenes in the ganoderma lucidum fermentation liquor is increased, the immunomodulatory activity of the ganoderma lucidum product can be enhanced, and the ganoderma lucidum product has relatively high effects of resisting oxidation, improving the activity of phagocytes, improving the activity of acid phosphatase, improving the immunity and the like, and has a wide application prospect and market potential.

The invention discloses lactobacillus mucilaginosus and application thereof in fermentation of sporoderm-broken ganoderma lucidum spore powder. The preservation number of the lactobacillus mucilaginosus is CGMCC (China General Microbiological Culture Collection Center) No.31453. The strain is separated and screened from vaginal secretions of healthy women at the childbearing age, is not hemolyzed, is sensitive to various common antibiotics and has strong lactic acid production capacity, and fermented supernate of the strain has strong growth inhibition capacity on escherichia coli, pseudomonas aeruginosa, staphylococcus aureus, salmonella typhimurium, shigella dysenteriae and gardnerella vaginalis and can be used for producing lactic acid. The compound has strong adhesion ability, growth inhibition ability and apoptosis promoting effect on human cervical cancer cells. When the strain is used for fermenting wall-broken ganoderma lucidum spore powder, the content of bioactive substances such as amino acids and derivatives thereof, fatty acids and steroids in fermentation liquor can be greatly increased, the strain has an obvious anti-inflammatory effect on DSS-induced mouse colitis, and the inflammatory factor level is remarkably reduced. The strain not only has significant application value in functional food and biological agents, but also opens up a new way for further development of ganoderma spores.

The invention discloses a multi-factor coupling ganoderma lucidum environment digital twinborn regulation and control method oriented to high-yield requirements, particularly relates to the technical field of intelligent cultivation of edible mushrooms, and is used for solving the problems of equipment action oscillation and recessive physiological stress caused by physiological response hysteresis of ganoderma lucidum in an existing environment regulation and control system. Carbon dioxide concentration and illumination intensity predicted values are generated in real time by constructing ganoderma lucidum growth digital twins, and an oxidative stress mark is activated by combining hypha respiratory entropy matching degree analysis and an active oxygen accumulation curve; when the matching degree exceeds a threshold value and oxidative stress exists, a metabolic overload signal is generated, and whether the carbon dioxide predicted value is in a physiological hysteresis interval or not is judged; delay compensation and metabolic overload suppression coefficient adjustment are performed on the carbon dioxide predicted value in the delay interval; and finally, inputting the compensated carbon dioxide value and the illumination prediction value into an environment factor coordination rule base, generating a ventilation opening degree and light supplementing power instruction to drive execution equipment, and ensuring the morphological development stability of the sporocarp and the synthesis efficiency of the active component.

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for tonifying qi and blood and treating hypomenorrhea caused by deficiency of qi and blood and a preparation method thereof. The composition is prepared by carefully selecting a plurality of traditional Chinese medicinal materials with the effects of tonifying qi and blood, regulating menstruation and nourishing blood and combining the traditional Chinese medicinal materials according to a specific proportion, and comprises ginseng, codonopsis pilosula, lucid ganoderma, astragalus membranaceus, angelica sinensis, peach kernels, donkey-hide gelatin, longan aril, Chinese dates, Chinese yams, radix polygonati officinalis, fructus lycii, poria cocos, roses and pericarpium citri reticulatae. The traditional Chinese medicine composition is prepared through the processes of extraction, double-effect concentration, filtration, blending and the like through scientific proportioning and a unique processing technology, aims to effectively improve the symptom of scanty menstruation caused by deficiency of qi and blood of women, recover normal menstruation, condition the body and improve the overall health level, has good safety and effectiveness, and is worthy of popularization and application. And a new choice is provided for health management of women. The traditional Chinese medicine composition for tonifying qi and blood and treating hypomenorrhea caused by deficiency of qi and blood is safe, small in side effect, efficient, convenient and good in taste.

The invention belongs to the technical field of health-care products, and particularly relates to a formula helpful for improving sleep and a preparation method thereof. Comprising the following raw material components in parts by weight: 90-110 parts of spina date seed powder, 45-55 parts of casein hydrolysate peptide powder, 15-22 parts of gamma-aminobutyric acid, 18-22 parts of lucid ganoderma powder, 15-22 parts of lily powder, 18-20 parts of poria cocos powder, 12-15 parts of tea leaf theanine and 1-4 parts of lactobacillus plantarum JYLP-326. According to the formula for improving sleep provided by the invention, the limitation of an existing insomnia treatment means is broken through through a three-dimensional synergistic network of traditional Chinese medicines, probiotics and functional components, and the formula realizes systematic improvement on insomnia core symptoms through multi-channel synergy of nerve regulation, intestinal brain axis intervention and immune balance, namely rapid induction of sleep.

The invention discloses a plant beverage capable of dispelling effects of alcohol, protecting liver and resisting fatigue and a preparation method thereof. The health-care tea is characterized by being prepared from the following raw materials in parts by weight: 1-12 parts of ginseng, 1-24 parts of rhizoma polygonati, 1-40 parts of radix puerariae, 1-24 parts of ampelopsis grossedentata, 1-24 parts of semen cassiae, 1-24 parts of mulberries, 1-40 parts of liquorice, 1-20 parts of hippophae rhamnoides fruit powder, 1-24 parts of poria cocos, 1-24 parts of smoked plums, 1-24 parts of rhizoma phragmitis, 1-40 parts of hovenia dulcis thunb, 1-24 parts of hawthorns, 1-24 parts of pericarpium citri reticulatae, 1-24 parts of lucid ganoderma and a proper amount of water. The preparation method comprises the following steps: pretreating raw materials, soaking, decocting, filtering, concentrating, blending, filling, sterilizing, inspecting and packaging. The beverage has the beneficial effects that the beverage has remarkable effects of dispelling effects of alcohol, protecting liver and resisting fatigue; no side effect exists; the mouthfeel is good; the preparation method is simple and low in cost; the tea is suitable for different people.

The invention discloses a ganoderma spore full-ingredient separation and utilization method and application, and belongs to the technical field of processing. The method comprises the following steps: S1, preparing emulsion and spore wall shells; s2, performing concentration and alcohol precipitation on the emulsion to obtain supernate and precipitate; s3, respectively drying the supernate and the precipitate to obtain a small molecule peptide component and a polysaccharide component; s4, performing enzymolysis on the spore wall shells by using a compound enzyme A and a compound enzyme B, and performing solid-liquid separation to obtain enzymatic hydrolysate and material residues; the compound enzyme A comprises cellulase and chitinase, and the compound enzyme B comprises papain, bromelain and alpha-amylase; s5, preparing soluble dietary fibers from enzymatic hydrolysate; s6, drying and extracting the residues to obtain ganoderma lucidum spore oil and residues; and S7, preparing chitosan from the residual materials. According to the method, separation of various products can be completed at a time, and full-ingredient separation and utilization of the ganoderma lucidum spores are achieved. Compared with the prior art, the yield of the spore oil and the soluble dietary fiber is higher, and the purity of the soluble dietary fiber can be improved.

The invention relates to a ginseng, ganoderma lucidum and red date preparation with anti-oxidation and anti-aging effects and application thereof, and belongs to the field of health-care food, and the preparation comprises a ganoderma lucidum polysaccharide extract, a ginseng extract and a red date polyphenol extract. According to the method, the high-voltage pulsed electric field is combined with the Sevage method to extract the ganoderan, the extraction efficiency and purity can be improved while the biological activity of the ganoderan is maintained, and the method has the advantages of being short in time, low in cost, easy and convenient to operate and the like and is suitable for industrial production. Meanwhile, the synergistic effect of the components is achieved, the optimal anti-oxidation and anti-aging effects are achieved, and the prepared ginseng, lucid ganoderma and red date oral liquid preparation has the excellent anti-oxidation and anti-aging effects.

The invention relates to the related technical field of daily chemical skin care products, in particular to a water aqua solution for scalp care and a preparation method thereof.The water aqua solution is prepared by mixing multiple raw materials in sequence, and the multiple raw materials comprise, by concentration, 0.005% of mixed cytokines, 0.005% of auxiliary agents and the balance water. The addition amount of the vitamin B12 is 0.00006%; the addition amount of allantoin is 0.2%; the addition amount of nicotinamide is 0.7%; the adding amount of the chamomile extracting solution is 5%; the adding amount of the aloe extracting solution is 5%; the addition amount of the ginkgo biloba extract is 5%; the addition amount of the lucid ganoderma extracting solution is 5%; the addition amount of the polyol preservative is 1%; the total percentage is 100%; according to the application, the mixed cell factors, the vitamin B12, the allantoin, the nicotinamide, the chamomile extracting solution, the aloe, the gingko, the lucid ganoderma, the polyol preservative and the water are mixed, so that the scalp absorption efficiency is improved, the safety of the product can be improved, and the maintenance effect is more obvious; the problems that an existing aqueous solution for skin curing is low in component action efficiency and insufficient in adaptability and safety are solved.

The invention relates to the technical field of natural compounds, in particular to ganoderma leukemia polysaccharide and a preparation method thereof. The ganoderma leukemia polysaccharide comprises galactose, glucose and mannose, and the molar ratio of the galactose to the mannose to the glucose is (1.5-3.5): (15-30): (65-85); the ganoderma leukemia polysaccharide comprises:-> 6)-Glcp-(1-> dominant residues; (-> 6)-Manp-(1->,-> 4)-Glcp-(1-> residue; and-> 4, 6)-Manp-(1->,-> 3, 6)-Galp-(1->. The ganoderma leukemia polysaccharide has anti-oxidation and detoxification capabilities, can avoid neurodegenerative diseases, reduce lipid accumulation and prolong the service life, and also has high-temperature resistance.

The invention discloses a compact mycelium-based high-efficiency durable sound insulation composite material and a rapid preparation method thereof, and relates to the field of biological building materials.The method comprises the steps that straw powder, corncob powder, wood chip powder, bran powder, soybean meal and an alkaline mixed additive are mixed to be uniform, aerogel particles, graphene nanosheets and water are added and stirred, and a mixture is obtained; a culture medium is formed, oyster mushroom strains or ganoderma fungus strains are evenly inoculated on the culture medium at the same time in a multi-point injection mode, the injection depth is the same, then the temperature is controlled to be 30-35 DEG C, the humidity is controlled to be 65%-75%, heating is conducted in a microwave heating mode under the ventilation condition, and after mycelia completely cover the culture medium, a culture system is obtained; the culture system is subjected to compression molding under the pressure of 2-5 Mpa, then vacuum drying is performed, the total water content is controlled to be 4% or below, the compact mycelium-based efficient and durable sound insulation composite material is obtained, the production efficiency and the material performance are improved, and no chemical pollution exists.

The invention discloses a ganoderma lucidum extraction method based on a reusable magnetic enzyme. The ganoderma lucidum extraction method comprises the following steps: S1, preparing a nanoscale amination modified Fe3O4-SiO2 magnetic composite carrier; s2, on the basis of the amination modified Fe3O4-SiO2 magnetic composite carrier, cellulase is added, and a magnetic immobilized enzyme buffer solution is obtained; s3, the ganoderma lucidum sporocarp is put into a magnetic immobilized enzyme buffer solution to be subjected to enzymolysis, extraction and filtration, effective components of ganoderma lucidum are obtained, and magnetic immobilized enzyme is recycled for repeated utilization; according to the method, the magnetic nanoparticles are modified, so that the surfaces of the magnetic nanoparticles have specific active groups, meanwhile, the magnetic response advantage of an inorganic magnetic material is reserved, the nanoscale amination-modified Fe3O4-SiO2 magnetic composite carrier is prepared, enzyme molecules can be directly anchored on the surfaces of the magnetic nanoparticles, and enzyme activity is improved. The immobilized enzyme can be conveniently recycled from a reaction system, so that the cost of an enzyme preparation can be reduced, and the enzyme activity stability can be improved.

The invention discloses a ganoderma lucidum extract dressing. The ganoderma lucidum extract dressing comprises ganoderma lucidum source chitosan, ganoderma lucidum polysaccharide, ganoderma lucidum source carboxymethyl chitosan and carbomer. The invention further discloses application of the lucid ganoderma extract dressing in promoting skin wound repair and preparing products for promoting skin wound repair. The invention further discloses a preparation method of the lucid ganoderma extract dressing. The lucid ganoderma extract dressing disclosed by the invention has antibacterial and hemostatic functions, can effectively avoid the situation that common chitosan generates a sensitization effect, accelerates the wound healing and repairing process, and effectively improves the wound healing situation.

The invention provides lucid ganoderma oligopeptide with an anti-tumor effect and a preparation method thereof. The three oligopeptides are separated and purified from the ganoderma lucidum for the first time, and the oligopeptides have broad-spectrum anti-tumor activity, can effectively inhibit tumor cell proliferation, have good biological compatibility and have great application prospects.

The invention discloses a construction method and application of an HPLC (High Performance Liquid Chromatography) specific chromatogram of sunburn prevention and treatment cream, and relates to the technical field of pharmaceutical analysis. The sunshine prevention and treatment cream is composed of honeysuckle, perfoliote knotweed herb, sedum sarmentosum, dayflower, radix polygonati officinalis, lithospermum erythrorhizon, aloe, asparagus fern, lucid ganoderma, coix seed and bee pollen, and is one of representative products of Guizhou Miao medicine brands. The specific chromatogram of the sunshine prevention and treatment cream is established by adopting a high performance liquid chromatography, and the five medicinal materials including honeysuckle, lithospermum erythrorhizon, aloe, sedum sarmentosum and perfoliote knotweed herb can be identified at the same time. The HPLC characteristic chromatogram of the sunshine prevention and treatment cream established by the method can effectively characterize the quality of the sunshine prevention and treatment cream, and is beneficial to comprehensively monitoring the quality of medicinal materials. Meanwhile, the method has the advantages of being simple, convenient, stable, high in precision, good in reproducibility and the like, and the authenticity of the product can be rapidly and accurately identified.

The present invention is applicable to the technical field of plant extraction and separation, and provides a method for extracting a polysaccharide compound from lucid ganoderma. The polysaccharide compound is used for treating advanced cancer patients (who have lost the conditions for surgery, have only three to six months left to survive, and are still eligible for chemotherapy), and a lucid ganoderma medicinal component polysaccharide compound is extracted from the polysaccharide compound at high temperature and high pressure. The polysaccharide compound containing the medicinal component has good water solubility, is easily absorbed by human bodies, has an anti-tumor medicinal effect and an effect of preventing the occurrence of tumors in humans, and can eliminate the toxic and side effects of chemotherapeutic drugs on human bodies especially when used in combination with the chemotherapeutic drugs; and there are corresponding experimental data to prove that the polysaccharide compound can control and reduce tumor masses, and reduce and eliminate tumor cells.

The invention belongs to the technical field of medicines, and particularly relates to application of pancreatin combined lucid ganoderma to preparation of a medicine for treating leucopenia. Research finds that when the lucid ganoderma is independently used, the treatment effect on leucopenia is poor. Compared with the prior art, the pancreatin combined lucid ganoderma can significantly increase the number of leukocytes, the increase amount is higher than the sum of the increase amounts of the pancreatin and the lucid ganoderma when the pancreatin and the lucid ganoderma are independently used, it is indicated that the pancreatin combined lucid ganoderma can be used for treating the leucopenia, the combination of the pancreatin and the lucid ganoderma has a synergistic effect, and more choices are provided for clinical treatment of the leucopenia.

The invention provides a new anti-tumor ganoderma lucidum variety, a related product as well as a preparation method and application of the new anti-tumor ganoderma lucidum variety, and belongs to the field of new ganoderma lucidum varieties. The new variety of ganoderma lucidum provided by the invention is classified and named as Ganoderma sichuanense Xianzhi No.13, and is preserved in the China Center for Type Culture Collection (CCTCC) on October 25, 2024, and the preservation number is CCTCC NO: M 20242347. Compared with the existing ganoderma lucidum variety, the new ganoderma lucidum variety provided by the invention has higher yield and higher content of effective components and anti-cancer active components, and the extract of the ganoderma lucidum has good anti-tumor activity.

The invention belongs to the field of shampoo, and discloses hair-blacking and alopecia-stopping Chinese herbal medicine shampoo and a preparation process thereof. The shampoo cream is prepared from the following raw materials in parts by weight: 10 parts of cacumen biotae, 10 parts of Chinese honey locust, 110 parts of soapberry, 6 parts of szechwan chinaberry fruit, 5 parts of lucid ganoderma, 5 parts of pine needle, 5 parts of eclipta, 5 parts of garden balsam stem, 5 parts of tea seed powder, 5 parts of rhizoma drynariae, 5 parts of glossy privet fruit, 5 parts of mulberry leaf, 4 parts of duckweed, 3 parts of polygonum multiflorum, 3 parts of angelica sinensis, 3 parts of tribulus terrestris and 2 parts of ginseng. The hair-loss-preventing and hair-growing shampoo has the comprehensive effects of preventing hair loss and growing hair, namely activating hair follicle activity, promoting hair cell proliferation and improving scalp microcirculation through the components such as the radix polygoni multiflori preparata and the cacumen biotae. The hair blackening and brightening agent contains eclipta, mulberry leaves and the like, can promote melanin synthesis, inhibit decomposition, repair damaged hair and enhance hair gloss. The effects of controlling oil, removing dandruff, relieving itching, resisting inflammation, nourishing and conditioning are achieved.

The invention relates to the field of skincare products, and particularly discloses skincare gel loaded with ganoderma lucidum exosome and a preparation method of the skincare gel. The skin care gel loaded with the lucid ganoderma exosome is prepared from the following raw materials in parts by weight: 20 to 40 parts of hydrogel matrix, 2 to 4 parts of lucid ganoderma exosome nanoparticles, 2 to 6 parts of niobium carbide nanosheets, 1 to 3 parts of nicotinamide, 0.1 to 2 parts of phenethyl resorcinol and 0.1 to 3 parts of green tea extract, the Mailing exosome nanoparticles are of a core-shell structure, a core layer comprises Mailing exosome and papain in a mass ratio of 1: (0.1-0.2), and a shell layer comprises a polylactic acid-glycolic acid copolymer and a penetration enhancer in a mass ratio of 1: (0.1-0.3). The skin-care gel provided by the invention has remarkable whitening, moisturizing and skin brightening effects.

The invention relates to the field of functional food processing, and discloses a qi-tonifying and blood-activating dietary therapy formula based on the theory of qi and blood in traditional Chinese medicine, which comprises astragalus membranaceus, angelica sinensis, red dates, lycium barbarum, lycium ruthenicum, ginseng, salvia miltiorrhiza, mulberry, lucid ganoderma, cordyceps mycelium, rhodiola rosea, American ginseng, acanthopanax, grape seed extract and chrysanthemum. Through a compound formula based on the theory of qi and blood in traditional Chinese medicine, and by combining various core medicinal materials and functional plants such as the astragalus membranaceus, the angelica sinensis, the ginseng, the lucid ganoderma, the rhodiola rosea and the fructus lycii, the multi-level effects of tonifying qi, enriching blood, activating blood, resisting oxidation and regulating immunity are achieved. The technical effects of comprehensively regulating qi and blood and improving body immunity and resistance are achieved through the synergistic effect of the compound components, compared with a scheme of regulating qi and blood by depending on a single component in the prior art, the compound formula remarkably improves the overall drug effect, solves the problems that a single component is limited in regulating function and insufficient in curative effect, and is suitable for popularization and application. Therefore, the requirements of modern people on comprehensive conditioning and immunity enhancement are met.

The utility model discloses a ganoderma lucidum spore powder activation wall breaking device, which relates to the technical field of ganoderma lucidum processing equipment and comprises a power base, an installation transmission unit and a wall breaking separation unit. The power base is of a cylindrical structure, and a wall breaking barrel is mounted on the upper side; the mounting transmission unit is mounted at the joint of the power base and the wall breaking cylinder; the wall breaking separation unit comprises a bearing sleeve, a material leakage plate, a transmission shaft, a rotating blade, blade strips and material passing holes, a row of blade strips are fixedly connected into the curved surface of the upper side of the rotating blade in a linear array mode, the section of each blade strip is of a triangular structure, and the slender material passing holes are formed between every two adjacent blade strips. According to the wall breaking device, the wall breaking barrel can be conveniently installed, taken and placed, power transmission is effectively achieved, the reliable wall breaking separation unit is arranged, tiny particles generated after wall breaking and the shell can be effectively stored in a separated mode, and the practicability of the device is greatly improved.

The invention relates to the technical field of nutritional health-care food, and particularly discloses functional oral liquid capable of tonifying qi and blood and enhancing immunity based on ganoderma lucidum active ingredients and a preparation method. The composition comprises a ganoderma lucidum fermentation stock solution, ginseng, lucid ganoderma, astragalus membranaceus, angelica sinensis, fructus lycii, fructus hippophae, rhizoma polygonati, oyster nano peptide, raspberry and a chitosan oligosaccharide-vitamin E stabilizer. The preparation method comprises the following steps: crushing medicinal materials, performing graded extraction, performing ultrasonic integration with a ganoderma lucidum fermentation stock solution, performing membrane separation and purification, performing gradient vacuum concentration, adding a stabilizer under the protection of nitrogen, stirring, and finally performing nitrogen filling and pasteurization. The composition disclosed by the invention can be used for tonifying qi and blood and regulating immunity, the bioavailability is improved by virtue of synergy of ganoderma lucidum polysaccharide, ganoderma lucidum triterpenes and ginsenoside and an oyster nano peptide-sea buckthorn flavone composite carrier, and efficient retention and synergistic interaction of active ingredients are realized; in addition, low-temperature gradient concentration and mild sterilization are adopted in the preparation method, so that the heating time is shortened, and the quality stability of the product is ensured.

The invention relates to the technical field of traditional Chinese medicine ointment, in particular to scalp ointment which is prepared from pilose antler, red kudzuvine root, dandelion, cistanche, cypress, glossy privet fruit, lucid ganoderma, gastrodia elata, sargentgloryvine stem, poria with hostwood, black sesame, mole cricket, garlic, pseudo-ginseng powder, raw ginseng powder, camel milk powder, almond powder, deer blood powder, fetus cervi powder, glycerin, disinfectant fluid and the like. The invention has the advantages that the pilose antler, cistanche and the like can relieve dizziness and headache in the aspect of improving blood circulation; in the aspect of regulating body functions, the radix puerariae and the combination of various medicinal materials can regulate qi and blood, soothe nerves and restore consciousness, and help a user get rid of fatigue; the dandelion, the lucid ganoderma, the gastrodia elata and the like can relieve the heavy feeling of the body and improve the sleep quality in the effects of eliminating dampness and soothing the nerves; cistanche deserticola, morinda officinalis and the like can regulate kidney deficiency and enhance waist strength. After long-term use, immunity can be enhanced, pathogenic bacteria can be resisted, the disease probability can be reduced, the life quality can be improved, and an effective nursing scheme is provided for head and whole body health.

The invention belongs to the field of microorganisms, and relates to a high-temperature-resistant lepista sordida strain and application thereof. The invention provides a brand-new lepista sordida new strain (Yao xiang mill No.1) which is obtained through separation and successfully preserved, and the lepista sordida can grow and fruit under a high-temperature condition, so that the lepista sordida can still be normally cultivated and fruit at a high-temperature period in Guangxi regions, especially regions around Nanning. The fungus is rich in nutrition, delicious in taste and rich in protein, 18 kinds of amino acid and other nutrient substances, not only is a good dining table item, but also has the effects of oxidation resistance, bacteria resistance, tumor resistance and the like, is rich in selenium, germanium, iron, zinc, calcium and other microelements, polysaccharide and trehalose (higher than shiitake mushrooms, lucid ganoderma and the like), and is an edible and medicinal fungus with high commercial value and medicinal research and development potential.

The invention belongs to the technical field of medicine, and discloses a sea cucumber and ganoderma lucidum immune steady-state compound and a composite enzymatic hydrolysis targeted liposome co-delivery preparation process thereof.The sea cucumber and ganoderma lucidum immune steady-state compound is composed of sea cucumber, ganoderma lucidum, American ginseng, dried oyster meat, fructus lycii and perilla leaves; the ganoderma triterpenes release free polysaccharides and are combined with a liposome intestinal targeted delivery system, so that the absorption rate of the polysaccharides is greatly improved to 18-22% from 5% in the traditional process, the ganoderma triterpenes are emulsified and entrapped through a liposome double-layer membrane, and meanwhile, the permeation promotion effect of perillaldehyde in the perilla leaf volatile oil is supplemented, so that the transmembrane transport efficiency is remarkably enhanced, the absorption rate is improved to 12-15% from 2%, and the bioavailability is improved. The zinc element decomposes oyster zinc protein into free zinc ions through a composite enzymolysis technology, and the free zinc ions and vitamin C form a stable chelate, so that the antagonism of intestinal tracts is reduced, the zinc absorption rate is increased from 20% to 45-50%, and a solid foundation is laid for fully playing a compound immune regulation effect.

The invention discloses a pharmaceutical composition for treating hashimoto thyroiditis, and belongs to the technical field of traditional Chinese medicines. According to the pharmaceutical composition, astragalus membranaceus and codonopsis pilosula are used as monarch drugs to tonify qi, raise yang, tonify qi and strengthen body resistance; radix bupleuri, rhizoma cyperi and radix curcumae are used as ministerial drugs for soothing liver-qi stagnation, expelling evil, soothing liver-qi, regulating qi and harmonizing blood; humifuse euphorbia herb, lucid ganoderma and oldenlandia diffusa are used as adjuvant drugs for clearing away heat and toxic materials, reinforcing qi, nourishing blood and tranquilizing; the whole formula has the effects of tonifying qi, soothing the liver and clearing heat together. All the medicines are combined to effectively improve the symptoms of patients with hashimoto thyroiditis and reduce the thyroid autoantibody level. In addition, the pharmaceutical composition is good in safety, and a traditional Chinese and western medicine combined treatment strategy for hashimoto thyroiditis can be further popularized in the future.