The invention discloses a vaginal secretion sampling device for obstetrics and gynecology department. The device comprises a sampling tube and a protective tube, a sampling head is in communication with the interior of the sampling tube, a plurality of sampling holes are formed in the sampling head, the protective tube comprises an outer protective tube body, an inner protective tube body, a protective head and connecting pieces, the outer protective tube body sleeves the outer side of the inner protective tube body, the inner protective tube body sleeves the outer side of the sampling tube, a gap is formed between the inner wall of the inner protective tube body and the outer side of the sampling tube, the protective head is arranged at the front end of the outer protective tube body, one end of the connecting pieces is hinged to the outer wall of the front end of the inner protective tube body, the other end thereof is hinged to the inner wall of the protective head, the inner protective tube body is pushed towards a front end, and therefore, the protective head is opened through the connecting pieces, and the sampling pipe can penetrate through the protective head. According to the vaginal secretion sampling device, through dual protection of the outer protective tube body and the inner protective tube body on the sampling tube, in the process that the sampling tube extends into the vagina, the sampling head is isolated from vaginal tissues, so that the sampled vaginal secretion is prevented from being polluted.