Sample collection for the Pap smear sample is critical for accurate diagnosis. Improper
sample collection, poor sampling, and / or
cell preservation can render a Pap smear unsatisfactory for evaluation, requiring a repeat smear collection. If the Pap smear does not contain appropriate representative cells from the transformation zone and endocervical canal, the ability of the test to detect
disease is very low. Likewise, if the preservation of the sample is compromised, the screener's ability to recognize
abnormal cells is greatly diminished. It is generally understood that cervical samples should be harvested by a two-stage technique, which includes sampling of the endocervical canal with a cytobrush and obtaining a sample from the transformation zone with a spatula. The use of either the cytobrush or the spatula alone may be adequate but not as effective as the two-stage technique. Both the Cervex
Brush and REG;(Unimar, Inc.) and the Accellon Combi & REG;(Medscand AB) are two collection devices which combine the action of the cytobrush and spatula, thus permitting broader sampling with a
one stage technique. The standard method of transferring
cervical cells from the collection device or complete transfer of the collection device into the liquid collection
vial is often challenging. These challenges include but are not limited to: 1-spilling the sample, 2-dispersing the medium collection such that air born body secretions could contact unprotected health
care workers, 3-missing the collection container and contaminating the sample. It is the goal of the current device embodiment to provide a simple and consistent method of transferring the entire collection specimen into the collection container to maximize
cell collection while minimizing challenges of head disengagement. Such devices are not limited to the
cervical cell cytology collection markets but extend to all
cell collection methods were the entire sample is suspended in a liquid or similar medium. Such samples include
oral cavity collections (
throat swabs, vaginal cavity collections (STDs,
pregnancy test), urethral cavity collections (male STDs) fornex collections (Alaph
fetal protein), and rectal collections as well as open procedures requiring cell sampling.