124 results about "Defecation" patented technology

To provide an absorbent article capable of suppressing adhesion of feces to a wearer's body. [Solution] The absorbent article 20 is configured to be attachable to a wearable body 10 for a pet P, which has a defecation hole 14 formed therein for allowing defecation to pass through. The absorbent article 20 comprises a main body 21 having a top sheet 23 arranged on the skin-facing side of the pet P, a back sheet 24 arranged on the non-skin-facing side opposite the skin-facing side, and an absorber 30 having an absorbent core 31 arranged between the top sheet 23 and the back sheet 24, the main body 21 having a back-side protrusion 50 that protrudes outward along the longitudinal direction Y from a back-side end 31b of the absorbent core 31 in the longitudinal direction Y, and the back-side protrusion 50 has independently foldable convex portions 52 formed therein, which are located inside outer ends 21s on both sides of the main body 21 in the width direction X and include a center line CL1 of the main body 21 along the longitudinal direction Y.

The invention provides a preparation method of a Witzia ciliaris IOB502 microbial inoculum and an application of the Witzia ciliaris IOB502 microbial inoculum in the aspect of recovering intestinal motility, the Witzia ciliaris IOB502 microbial inoculum is prepared by adopting a method of carrying out low-oxygen stress staged fermentation on chickpeas by adopting the Witzia ciliaris IOB502, and the generation of vitamins B1 and B2 can be promoted. The microbial inoculum does not affect physiological development of important organs such as liver, spleen and small intestine of mice, can improve defecation symptoms of the mice with constipation, increase defecation times and water content of excrement, improve intestinal movement of the mice with constipation, promote smooth passage of intestinal contents, effectively improve colon injury of the mice with constipation, and improve the constipation rate of the mice with constipation. Comprising mucous membrane layer thinning and mucus secretion reduction.

The invention discloses bifidobacterium longum subsp. Infantis for regulating intestinal motility and aquaporin and application of the bifidobacterium longum subsp. Infantis, and belongs to the technical field of microorganisms. According to the invention, the bifidobacterium longum subsp. Infantis CCFM1269 is screened, and the bifidobacterium longum subsp. Infantis CCFM1269 has the effects of intestinal motility and aquaporin, specifically, the defecation frequency is reduced, and the water content of excrement and the small intestine propulsion rate are reduced. The intestinal motility abnormality is relieved by reducing the levels of neurotransmitters 5-HT, SP and VIP, and the intestinal moisture absorption and secretion are regulated by improving the mRNA expression of aquaporin AQP4 and AQP8. Meanwhile, the intestinal flora is adjusted by improving the diversity of the intestinal flora, and the content of propionic acid and butyric acid in excrement is increased.

The utility model relates to the technical field of medical care instruments, and discloses a puerpera quick defecation auxiliary device which comprises a base, an electric push rod is fixedly connected to the upper surface of the base, a U-shaped seat is fixedly connected to the output end of the electric push rod, a transmission rod is fixedly connected to the interior of the U-shaped seat, and a fixing frame is slidably connected to the outer wall of the transmission rod. A connecting rod is fixedly connected to the interior of the fixing frame, a special-shaped block is rotatably connected to the outer wall of the connecting rod, the interior of the special-shaped block is slidably connected to the outer wall of the transmission rod, a backrest is fixedly connected to the upper surface of the special-shaped block, and a fixing block is fixedly connected to the lower surface of the backrest. According to the utility model, through the mutual cooperation of the electric push rod, the U-shaped seat, the transmission rod, the fixing frame, the connecting rod, the special-shaped block, the fixing block and the limiting assembly, the angle of the backrest is adjusted, so that the effects of relieving body burden, promoting intestinal tract movement and further promoting defecation are achieved, and meanwhile, the comfort level and the psychological state of a puerpera are also improved.

The present invention relates to a feces determination method, a feces determination device, and a feces determination program. The feces determination device acquires image data of feces captured by a camera that captures an inside of a bowl of a toilet, calculates a G / R value and a B / R value based on R (red) values, G (green) values, and B (blue) values included in the image data, determines whether or not an image of at least one of defecation, urination, and bleeding is included in the image data based on the G / R value and the B / R value, and outputs a result of the determination.

The invention discloses a mechanical defaecation device, belongs to the technical field of medical instruments, solves the problem of poor defaecation effect in the prior art, and adopts the technical scheme that the mechanical defaecation device comprises an insertion piece capable of extending into the anus, an excrement storage piece with a suction function and a communicating piece for connecting the insertion piece and the excrement storage piece, a rotary grinding head used for crushing excrement blocks is arranged at the front end of the inserting piece, a power assembly used for driving the rotary grinding head to rotate and a flushing channel used for conveying flushing fluid to the area where the rotary grinding head is located are arranged in the inserting piece, and the inserting piece is provided with a suction inlet communicated with the communicating piece. The suction inlet is located in the area where the rotary grinding head is located. According to the invention, the bowel relaxing effect is improved.

The utility model belongs to the technical field of auxiliary defecation equipment, and particularly relates to an auxiliary defecation device. The top of the bottle neck is of a closed structure, the bottom of the bottle neck is connected with a bottle body communicated with the bottle neck, glycerine enema is arranged in the bottle body, the bottle neck is sleeved with a soft sleeve, one end of the soft sleeve is fixed to the outer side wall of the bottle neck, a convex ring is fixed to the other end of the soft sleeve, and the convex ring is made of soft materials. The bottle neck is sleeved with the soft sleeve, one end of the soft sleeve is fixed to the bottle neck, the convex ring is arranged at the other end of the soft sleeve, and after the bottle neck is cut open, the convex ring is turned to the cut-open position of the bottle neck to shield the bottle neck; due to the fact that the protruding ring is made of the soft material, the protruding ring replaces the bottle neck to be in direct contact with the anorectum of the patient, and the problem that the bottle neck is inserted into the anorectum of the patient, and stabbing is easily caused can be solved.

The closable excrement collecting device comprises an excrement hopper, a collecting bag used for collecting excrement of a patient is placed in the excrement hopper, and a bag opening of the collecting bag is fixedly attached to an opening of the excrement hopper through a fixing ring. A rotating disc is rotatably installed in the urinal, a linear groove is formed in the upper end face of the rotating disc, and when excrement is stored in the collecting bag, the collecting bag deforms and is attached to the groove wall of the groove to form a linear long-strip shape, so that when the rotating disc rotates, the rotating disc and the collecting bag synchronously rotate. And a driving mechanism for driving the turntable to rotate is mounted on the urinal. According to the utility model, by utilizing the driving mechanism, a user can automatically seal the collecting bag in the urinal by utilizing an instrument after defecation is finished, so that peculiar smell dispersion and bacterium breeding caused by the fact that the collecting bag cannot be sealed in time when a nursing worker is absent are avoided.

The application provides bifidobacterium longum MG-G763 for improving constipation, and belongs to the technical field of microorganisms. The bifidobacterium longum MG-G763 provided by the application can effectively relieve constipation by integrating multiple effects such as nerve regulation, immune regulation, barrier repair and flora regulation, and systematically restoring intestinal function homeostasis. The bifidobacterium longum MG-G763 can significantly improve the defecation particle number and defecation weight of constipated mice, shorten the time for defecating the first black stool, improve the small intestinal transport rate of the mice, effectively improve and relieve the defecation condition of the constipated mice, and significantly increase the amount of intestinal beneficial bacteria and reduce the amount of harmful bacteria, thereby promoting intestinal health.

[Problem] To provide a pet diaper capable of forming an excretion bag in a three-dimensional shape at the time of defecation and easily storing excrement in the excretion bag at the time of defecation. [Solution] A pet diaper 10 comprises a diaper body 11 and an excretion bag 13 that is connected to the outside of the diaper body 11 and that has an internal space 13a thereof communicated with the inside of the diaper body 11 via a window part 12, the pet diaper 10 fitted to a posterior portion 15b such that a tail 15a penetrates the diaper body 11 and the excretion bag 13, and excrement 15e at the time of defecation passes the window part 12 and is stored in the internal space 13a of the excretion bag 13. The pet diaper 10 is provided with a shape adjusting means 17 for adjusting the shape of the excretion bag 13, and the shape adjusting means 17 comprises a tail-adapting portion 18 which is provided to a wall part 14a of the excretion bag 13 at a position facing the window part 12 and which, in accordance with the thickness of the tail 15a, can adjust a tail hole 19b through which the tail 15a passes.

The invention provides a cleaning and disinfecting device for the anorectal department, and belongs to the technical field of medical instruments. Comprising an infusion pump and a cleaning pipe, the positioning assembly is used for cleaning and disinfecting the anus of a patient, the positioning assembly is connected with the cleaning pipe, the positioning assembly comprises a positioning cylinder and a blocking and discharging plate which are arranged outside the cleaning pipe in a sleeving mode, and the blocking and discharging plate is clamped and fixed to the bottom of the positioning cylinder. Through the arrangement of the positioning assembly, the supporting air bag can gradually and slowly support the anus of a patient after being inflated, so that friction between the cleaning pipe and a wound surface in the flushing process is avoided, pain of the patient in the flushing process is relieved, tissue in the rectum of the patient can be supported after the expansion air bag is inflated, and the cleaning effect is improved. The excrement is conveniently softened by means of water sprayed out of the cleaning pipe in the later period, the excrement softening efficiency is improved, the softened excrement is more easily discharged out of the body of the patient, and large friction between the excrement and the wound surface in the defecation process of the patient is avoided.

The utility model provides a hip lifting air cushion for defecating on a bed. The hip lifting air cushion comprises an air cushion body, a containing bag, an air conveying pipe and an inflation pump. The air cushion body is provided with a containing cavity, a mounting cavity is formed in the top face, and a fixing base is arranged at the bottom. The accommodating bag is detachably mounted in the mounting cavity; one end of the air delivery pipe is communicated with the accommodating cavity, and the other end extends outwards; the inflator pump is connected with the other end of the air delivery pipe and can input air into the accommodating cavity; before use, the air cushion body is inflated to expand the air cushion; then, the air cushion body is sleeved with a garbage bag, a part of the garbage bag enters the containing bag, and the edge of the garbage bag is fixed to the fixing base; during use, the air cushion body is placed in an excretion area below a patient; after defecation is completed, the air cushion bed body is taken out, and the garbage bag is arranged and discarded. The lifting air cushion can lift the buttocks of a patient all the time, is convenient to clean and manage, large in size and mass, stable and not prone to displacement, and reduces pollution and infection risks of a bed sheet.

The invention relates to the technical field of traditional Chinese medicine oral liquid preparation, in particular to compound traditional Chinese medicine oral liquid for relaxing bowel and a preparation process thereof. The preparation process of the compound traditional Chinese medicine oral liquid for relaxing bowel comprises the following steps: preparing the achyranthes aspera extract and the radix glehniae stem and leaf extract; preparing glutinous rice banana fermentation liquor; preparing fermented litchi juice; preparing the compound traditional Chinese medicine oral liquid. The preparation method comprises the following steps: pulping glutinous rice banana pulp, carrying out enzymolysis by using enzyme, adding a complex microbial inoculant, fermenting to prepare a glutinous rice banana fermentation broth, mixing the glutinous rice banana fermentation broth with a tuber fleeceflower stem extract and the like to prepare the composite traditional Chinese medicine oral liquid, and the anthraquinone component of tuber fleeceflower stem has a strong effect, is biased to'treatment of symptoms', and rapidly solves symptoms. And the glutinous rice banana fermentation liquor focuses on treating the root and recovering the health function of the intestinal tract for a long time by regulating flora and nourishing the intestinal tract, and the combination of the glutinous rice banana fermentation liquor and the glutinous rice banana fermentation liquor can realize the unification of quick effect taking and long-term regulation to achieve the synergistic bowel relaxing effect.

The utility model discloses a kind of excrement collecting devices, it relates to medical instrument technical field.The excrement collecting device includes flexible band-shaped collecting bag, its one side is provided with the insertion tube being communicated with the inside of collecting bag, the distal end of the insertion tube is equipped with the anti-drop ring of expansion, for inserting into patient anus and being clamped by anti-drop ring anal inner wall;The collecting bag is provided with adhesive layer in the surrounding area of insertion tube, for adhering to the skin of patient anal periphery;Collecting bag body is provided with at least two groups of sealing strips along length direction interval, and the sealing strip is horizontally through bag body two sides;Sealing strip is in initial state for open state to make collecting bag internal communication, when needing sectional sealing, by closing two adjacent sealing strips at target position, and cutting bag body between two sealing strips, to separate lower bag body containing stored excrement.The excrement collecting device can take down stored defecation as required.

The invention relates to the technical field of food processing, and discloses sodium hyaluronate modified lipidosome embedded fructo-oligosaccharide prebiotics as well as a preparation method and application thereof. The sodium hyaluronate modified lipidosome is used for embedding fructo-oligosaccharide, so that the residence time of the lipidosome in intestinal tracts is prolonged, the release period of the prebiotics is prolonged, and the continuous action with the probiotics is ensured. The prebiotic fruit and vegetable fermented beverage with the bowel relaxing effect is prepared by matching the fructo-oligosaccharide embedded by the sodium hyaluronate modified lipidosome with the fermented mixed fruit and vegetable juice. The beverage can promote intestinal tract movement, repair mucous membrane barriers, form double effects of flora regulation and intestinal tract repair, also can increase beneficial flora in intestinal tracts, reduce harmful flora in the intestinal tracts and the like, solves the problems of short retention time and low utilization rate of prebiotics in the intestinal tracts, and provides a new method and raw materials for development of probiotic foods.

The invention provides a magnetic force driven alternate clamping type artificial anal sphincter prosthesis, which comprises an upper clamping device, a lower clamping device, an upper clamping device and a lower clamping device, wherein the upper clamping device is used for clamping a first part of an intestinal tract and can be opened or closed through magnetic force driving; the lower clamping device is used for clamping a second part of the intestinal tract and can be opened or closed through magnetic force driving, and the magnetic force threshold value of the lower clamping device is larger than that of the upper clamping device; the linkage part is connected with the upper clamping device and the lower clamping device and enables the upper clamping device and the lower clamping device to be in linkage. According to the artificial anal sphincter device, a magnetic force driving mode is adopted, the upper clamping device and the lower clamping device are used for alternately clamping an intestinal canal, clamping is carried out in a large-area plane, an excrement temporary storage stage is preset, an intestinal pressure monitor is matched for defecation early warning, and manual operation is not needed; the artificial anal sphincter prosthesis can effectively reduce the risk of injury and infection caused by the fact that the intestinal tract is in a clamping state for a long time, and is safe, stable, good in excrement control and convenient in energy supply.

The utility model relates to squatting device technical field, concretely is no lip formula splash squatting pan with inclined flush formula buffer platform, including foot rest platform, the middle part of foot rest platform is installed with squatting groove, the top of squatting groove is provided with squatting mouth, the bottom of squatting groove is provided with defecation mouth, the upper side edge of defecation mouth is provided with a ring for preventing the buffer platform that splashes up, the bottom of defecation mouth is connected with sewage pipe, and the outside of the junction of the upper portion of sewage pipe and defecation mouth is sealed through sealing element. In the no lip formula splash squatting pan with inclined flush formula buffer platform, in the splash effect aspect, the annular buffer platform that surrounds setting is arranged on the upper side edge of defecation mouth, and the annular buffer platform extends upwardly and inclines from the edge of defecation mouth to the inside of squatting groove, when excrement falls, the buffer platform can change its falling track and impact force direction, and reduce the splash of water; at the same time, the arc surface between the upper edge of buffer platform and the inner wall of squatting groove, further buffer excrement impact, double structure greatly promotes splash performance, avoids the user being splashed.

The invention provides a micro-enema preparation and quantitative evaluation method for improving the quality of a rectum magnetic resonance image, and the method comprises the steps: S2, carrying out a glycerine enema micro-enema operation, squeezing glycerine enema into the rectum, maintaining the operation for a preset time, and recording the defecation frequency and the last defecation character; s3, selecting the dosage of the microenema enema, carrying out grouped experiments by setting a plurality of doses, recording related scores, and selecting the dosage of the enema enema meeting clinical requirements; s4, selecting an on-machine time window before magnetic resonance examination after microenema, performing rectum magnetic resonance examination at a plurality of time nodes after defecation through grouping experiments, observing related scores, and selecting an on-machine time window with a good intestinal tract preparation effect; and S5, carrying out micro-enema adverse reaction evaluation, evaluating a plurality of grades of the subject, calculating an adverse reaction score according to a weighting formula, carrying out clinical decision making, and if the adverse reaction score is lower than a threshold value, terminating the operation and carrying out further processing.

This invention belongs to the field of traditional Chinese medicine treatment of acute kidney injury, and provides a traditional Chinese medicine composition for treating sepsis-related acute kidney injury and its preparation method. It is prepared by mixing honeysuckle, forsythia, roasted peach kernel, raw rhubarb, raw astragalus, wine-processed angelica, cinnamon twig, mirabilite, and raw licorice in a certain proportion. It detoxifies and removes blood stasis, invigorates qi and unblocks the meridians. It is used for persistent high fever and difficulty in urination and defecation caused by internal accumulation of toxic heat and blood stasis. Symptoms include oliguria or dribbling, red tongue, and rapid pulse; it is also used for sepsis patients with the above symptoms. Treatment with the detoxifying and blood-stasis-removing granules improved survival rate, effectively restored some renal function, reduced renal tubular damage, and decreased TNF-α and IL-1β expression. Immunohistochemical and Western blot results were consistent. The detoxifying and blood-stasis-removing granules can alleviate sepsis-induced acute kidney injury.

This invention relates to the field of food technology, and in particular to a protein powder that promotes bowel movements. To address the problems of some protein powders with added dietary fiber, such as poor compatibility between dietary fiber and protein, poor solubility, rough texture, and insignificant bowel improvement effects, ultimately leading to constipation, this invention comprises whey protein powder, casein powder, inulin, fructooligosaccharides, psyllium husk powder, soybean lecithin, and β-mannanase. This protein powder offers dual benefits of protein supplementation and intestinal health regulation. It efficiently supplements the protein needed by the human body, improves protein absorption and utilization, and is suitable for individuals with lactose intolerance and weak intestinal function. Simultaneously, through the synergistic effect of prebiotics, dietary fiber, and enzymes, it gently improves constipation symptoms, regulates intestinal flora balance, enhances intestinal peristalsis, and fundamentally protects intestinal health.

The invention relates to a composition for promoting pet hair discharge as well as a preparation method and application thereof. The composition comprises chicken, compound cellulose DR04, probiotics and digestion coenzyme, the composite cellulose DR04 comprises a Cunninghamia lanceolata extract, apple fiber powder, a beet extract and psyllium husk powder. According to the composition for promoting hair removal of pets, the cedarwood extract in the composite cellulose DR04 is insoluble fiber, forms a loose net-shaped structure to disperse hair after entering the intestinal tract, can promote intestinal tract movement, and helps cats to remove hair balls in the belly in a defecation mode. The Cunninghamia lanceolata extract is compounded with the apple fiber powder, the beet extract and the psyllium husk powder, so that wrapping and pushing dual promotion of hair removal is realized, and the hair removal efficiency is improved. The chicken, the probiotics and the digestion coenzyme are also added, so that the pet hair removal is further promoted, the palatability of the composition is also improved while the intestinal mucosal barrier is improved, and the composition is more suitable for being eaten by pets.

The defecation device comprises a syringe, a threaded outer pipe and a spray pipe, the spray pipe is provided with a limiting assembly, and the limiting assembly comprises a spring, a limiting plate and a limiting plug. By arranging the limiting assembly, the limiting plug firstly makes contact with the anus of the patient, direct impact and friction of the spray pipe on the anus of the patient can be effectively reduced, the risk of anus damage is reduced, meanwhile, the elasticity of the spring can provide certain resistance, medical staff can be helped to better control the depth of the spray pipe entering the anus of the patient, and the safety of the patient is improved. Discomfort or injury caused by too deep insertion is avoided, so that a patient feels more comfortable in the use process; by arranging the liquid receiving cover, redundant liquid can be effectively collected in the liquid receiving cover, the liquid is prevented from splashing out or flowing to other parts of the body of a patient, meanwhile, pollution of the liquid generated in the bowel relaxing process to the surrounding environment can be reduced, cleanliness and sanitation of the treatment environment can be kept, and the risk of cross infection is reduced.

The invention provides a defecation device for constipation patients, and belongs to the field of medical instruments. Comprising a machine body, a fixing pipe is fixedly connected to the outer surface of the upper end of the machine body, a dredging pipe is rotatably connected to the inner side of the fixing pipe, a lubricating assembly is arranged on the outer surface of the dredging pipe and comprises a guide groove formed in the upper side of the outer surface of the dredging pipe, and balls are rotatably connected to the inner side of the guide groove. By arranging the lubricating assembly, a ball can make contact with the upper side of a cotton swab in the rotating process, so that lubricating liquid is evenly smeared on the surface of the ball, the ball makes contact with the inner membrane of the rectum of a patient, the lubricating effect can be achieved in the dredging pipe inserting process, and therefore the friction force between the dredging pipe and the rectum of the patient can be effectively reduced; the dredging pipe is inserted more smoothly, the discomfort of a patient in the bowel relaxing process can be effectively relieved, part of lubricating liquid can be absorbed by excrement in the intestinal tract, and therefore the moisture of the excrement can be increased to a certain degree.

To solve the problem of the present invention, a biological electrode for measuring an action potential of an intestine and predicting a defecation timing based on the potential waveform, an intestinal potential measuring device using the biological electrode, and a defecation prediction method are provided. The biological electrode (2) includes a sheet body (3) having a back surface (31) as an attachment surface (31). The sheet body (3) includes a plurality of electrode patch portions (300, 301) that can be arranged at intervals along an intestinal canal (91) of a large intestine and have electrodes (4) for acquiring an intestinal potential exposed on the back surface (31), a central device mounting portion (310, 301) that is arranged within a range in which the plurality of electrode patch portions (300, 301) are annularly connected and has a plurality of connected terminals (311) that are electrically connected to connection terminals (50) of an electrogastrograph (5) and a mounting portion (312) for temporarily fixing a temporary fixing portion (51) of the electrogastrograph (5) exposed on a surface (30), and a lead wire extension portion (320, 321) in which lead wires (322) that connect the plurality of electrode patch portions (300, 301) and the plurality of connected terminals (311) are fixed, respectively.

The invention relates to the technical field of medical instruments, in particular to a defecation assisting device which comprises a handheld push-pull part, a long handle, a push-pull rod and an outward shifting part, the long handle is a tubular rod, the push-pull rod slides in the long handle, the length of the push-pull rod is larger than that of the long handle, the outward shifting part is fixed to the upper end of the push-pull rod, and the handheld push-pull part is in threaded connection to the lower end of the push-pull rod. The disposable defecation assisting device solves the problem that when an existing disposable defecation assisting device is adopted to assist a patient in defecation, due to the fact that a long handle stretching into the rectum of the patient rubs with the rectum mucosa repeatedly, the rectum mucosa of the patient is damaged.

The utility model discloses a backflow enema negative pressure drainage device which effectively solves the problem that the defecation effect is poor when a child patient is subjected to backflow enema. Comprising a connecting block, the upper end of the connecting block is detachably connected with an enema sleeve, the lower side of the enema sleeve is in a big-end-up funnel shape, the upper end of the enema sleeve is fixedly provided with a cannula communicated with the enema sleeve, and the outer end of the lower side of the enema sleeve is fixedly provided with an oval shielding air bag cushion; vertically-through connecting holes are formed in the upper side walls of the waste liquid cylinder and the elastic telescopic air bag correspondingly, baffles are hinged to the upper side walls of the waste liquid cylinder and the elastic telescopic air bag correspondingly through pin shafts, the baffles can shield the lower sides of the connecting holes, a moving block capable of sliding left and right is arranged in the connecting block, and a vertically-through circular groove is formed in the moving block; the upper end of the circular groove can be communicated with the clysis sleeve, and the lower end of the circular groove can be communicated with the connecting hole; the device is simple in structure, convenient to operate, novel in conception and high in practicability.

The present application relates to the field of probiotics and prebiotics, and in particular to the use of Citrus aurantium, Chichorium intybus, Elsholtzia stauntoni and Hamamelis virginiana as prebiotic mimics (pseudobiotics) that are both medicinal and edible. We first demonstrated that the water extracts of these medicinal and edible herbs significantly improved the constipation symptoms of model mice, improved the pathological damage of the colon of constipated mice, significantly increased the expression of proteins related to intestinal peristalsis and maintenance of the intestinal barrier, promoted the colonization of beneficial bacteria in the intestines of constipated mice, and exhibited effects similar to prebiotics. Therefore, any one of Citrus aurantium, Chichorium intybus, Elsholtzia stauntoni and Hamamelis virginiana or a combination thereof, or a mixture prepared with other substances, can be used to treat constipation in mice, and the mechanism of action may be related to promoting intestinal peristalsis, enhancing the function of the intestinal barrier, and increasing the abundance of beneficial bacteria in the intestines.

The utility model discloses a flexible dosing device with a physical defecation inducing function, which comprises a bottle body for storing liquid medicine and a bottle rod for conveying the liquid medicine, a step is arranged on the bottle rod, the bottle rod is divided into two sections by the step, and the two sections comprise a front rod section and a rear rod section; a rubber coating layer is coated on the front rod section; a through groove is formed in the rubber coating layer, and the through groove and the outer wall of the front rod section form a groove; the inner wall of the through groove is in an irregular shape. The rubber coating layer is made of a soft material; in the daily use process, due to the arrangement of the rubber coating layer and the through groove, when glycerine enema is inserted, the local part of the rectum wall can be squeezed into a groove formed by the through groove and the outer wall of the front rod section, when the front rod section moves, the rectum wall can be reversely squeezed by the inner wall of the through groove, the intestinal wall is physically stimulated, and therefore the rectum wall can be prevented from being damaged. The effect of inducing defecation reflex is achieved, so that defecation meaning is generated, and defecation is promoted.

The present invention relates to the field of probiotics, in particular to an Akkermansia muciniphila MG784 for alleviating constipation, promoting defecation, improving intestinal barrier function and intestinal immunity, and its uses. The Akkermansia muciniphila MG784 provided by the present invention has the deposition number DSM 35549. The Akkermansia muciniphila MG784 provided by the present invention can increase the levels of motilin (MTL), gastrin (GAS), and acetylcholine in the gastrointestinal tract, promote intestinal peristalsis, improve the small intestine propulsion rate, and ameliorate defecation time and fecal output. Furthermore, Akkermansia muciniphila MG784 can also alleviate colonic mucosal inflammation, improve the thickness of the digestive tract muscular layer, modulate the structure of the intestinal microbiota, significantly increase the abundance of beneficial bacteria, and decrease the abundance of harmful bacteria.

This invention discloses a novel application of Bifidobacterium breve CCFM1078 in relieving intestinal colic, belonging to the fields of microbial technology and pharmaceutical technology. The Bifidobacterium breve CCFM1078 provided by this invention can relieve intestinal colic in infants and young children, specifically in the following ways: (1) increasing the visceral pain threshold and reducing the frequency of defecation in rats to a certain extent; (2) reducing the number of chromaffin cells and 5-HT content in the colon of rats with intestinal colic; (3) reducing the serum TNF-α and IL-1β content in rats with intestinal colic; (4) reducing the hippocampal TNF-α and IL-6 content in rats with intestinal colic; and (5) increasing the propionic acid content in the cecal contents of rats with intestinal colic.