54 results about "Butyric acid" patented technology

The present invention relates to nutritional compositions comprising digestible carbohydrates, lipids, proteins, 3-fucosyl lactose (3-FL) and a butyrate source, which are suitable for providing nutrition to an infant or young child suffering from or at risk of developing a food allergy, preferably cow milk protein or egg allergy, wherein the protein is or consists essentially of hydrolysed protein and / or free amino acids, and wherein the butyrate is provided in the form of dietary butyrate and / or by non-digestible saccharides selected from non-digestible polysaccharides, non-digestible oligosaccharides or mixtures thereof capable of undergoing microbial fermentation in the gastrointestinal tract to produce butyrate, and uses thereof.

The application belongs to the technical field of food processing, and particularly relates to a processing method for improving aroma components of sweet potato stem and leaf powder. In the application, a traditional preparation process of sweet potato stem and leaf powder is improved, that is, a combination of ultra-low temperature crushing and superheated steam treatment is adopted to prepare a kind of sweet potato stem and leaf powder. In the obtained sweet potato stem and leaf powder, the total amount of volatile aroma substances is increased by 21.95% compared with that of the sweet potato stem and leaf powder prepared by the traditional method, wherein the relative content of 2-methyl butyric acid ethyl ester is increased from 0.35% to 2.17%, the relative content of terpinolene is increased from 0.12% to 2.15%, and the relative content of 1-pentene-3-ketone is increased from 0.21% to 1.52%. These aroma components endow the sweet potato stem and leaf powder with unique and strong original aroma of sweet potato, and significantly improve the quality of the sweet potato stem and leaf powder.

The application discloses a cream cheese and a preparation method and application thereof, and relates to the technical field of dairy products. The raw material of the cream cheese comprises light cream, the content of saturated fatty acids of the light cream is 69-72 wt%, the content of butyric acid in the light cream is 3-4 wt% based on total fatty acids, the content of myristic acid is 10-12 wt%, the content of palmitic acid is 32-35 wt%, the content of stearic acid is 8-11 wt%, and the ratio of palmitic acid to stearic acid is 3-4:1. The cream cheese is subjected to gradient temperature recovery ripening after filling, and the specific process is as follows: after filling, the cream cheese is cooled to 4-6 DEG C at a cooling rate of 1-2 DEG C / min, then is heated to 12-15 DEG C at a heating rate of 0.1-0.6 DEG C / min, is kept for 4-6 h, and is cooled to 4-6 DEG C again at a cooling rate of 0.6-2.2 DEG C / min. The cream cheese disclosed by the application has a more concentrated and layered flavor, and has a delicate and soft texture and good spreadability.

The application discloses Zanthoxylum bungeanum miR167b The application belongs to the technical field of genetic engineering, and discloses a gene in the application of regulating plant growth and development miR167b The application constructs an expression vector of the gene, and makes the gene overexpress in tomatoes, and finds that miR167b The overexpression plant is dwarfed, the shape of the fruit is changed, the size and weight of the fruit are significantly lower than those of the wild type, the fruit setting rate is high, the fruit is seedless, the number of fruit chambers is reduced, ovule abortion occurs, and no embryo sac is formed in the interior. Further analysis finds that the indole butyric acid content in the fruit of the overexpression plant is increased, which indicates that miR167b The gene can regulate auxin to induce fruit apomixis, lays a foundation for revealing the apomixis mechanism of Zanthoxylum bungeanum, and provides gene resources and basis for improving the breeding strategy of woody plants, and has important theoretical value and application prospect.

A biological control method for centipede breeding belongs to the field of special economic animal breeding technology. This invention uses a compound probiotic strain of *Trichoderma longicornis*, *Streptomyces flavus*, *Bacillus subtilis*, *Bacillus licheniformis*, *Clostridium butyricum*, and lactic acid bacteria, which is fully incorporated into the breeding substrate. After 24-72 hours of static setting, the bacteria fully colonize and form a stable antibacterial state. The bacterial community can remain dormant during periods of nutrient deficiency, low-temperature overwintering, or year-end static setting, and will revive upon contact with organic matter. The method is supplemented with springtails and pink woodlice, which preferentially consume harmful bacteria, clean up uneaten feed, and primarily feed on and decompose centipede feces, forming a mutually beneficial symbiotic relationship with the biocontrol bacteria. Their feces further nourish the bacterial community, extending the stable effective period of the bacterial community from 2 months to 4-6 months or more. Simultaneously, probiotics and vitamins are added to the feed to strengthen the centipede's constitution. This invention constructs a three-dimensional synergistic prevention and control system that integrates matrix inhibition of pathogenic bacteria, environmental residue removal, and internal administration for enhanced protection. This system enables drug-free ecological disease control, significantly reduces the incidence of diseases such as green muscardine, and improves the survival rate of centipede farming. It is suitable for large-scale centipede farming.

This invention provides the application of a *Breago brevis* strain in the preparation of products that promote intramuscular fat deposition in livestock and poultry. The *Breago brevis* strain is *Breago brevis* JCM 32280. Under high-fiber dietary conditions, supplementation with *Breago brevis* JCM 32280 of this invention can efficiently degrade fiber to produce high concentrations of butyrate. Butyrate, as a key effector molecule, can directly bind to and activate PPARγ receptors in host cells, thereby upregulating the MOGAT2-mediated triglyceride synthesis pathway, significantly increasing body fat percentage in mammals and promoting intramuscular fat (marbling). Simultaneously, this strain can reshape the intestinal microecology, specifically increasing the abundance of beneficial intestinal lactobacilli and enhancing the intestinal mucus barrier, providing a safe and efficient microbial preparation strategy for improving the fat deposition capacity and meat flavor of livestock and poultry.

The application discloses a kind of low morbidity feed for California bass antibiotic-free breeding and preparation method thereof, belong to aquatic feed field.The feed is composed of 60~80 parts of basic feed component, 10~20 parts of fermented plant protein, 2~6 parts of functional compound additives.Fermented plant protein is prepared by compound fermentation of butyric acid clostridium and bacillus subtilis from soybean meal, bran, rice bran, brown sugar and the like.Functional compound additives include pre-embedded material and microcapsule coated sodium butyrate, and the pre-embedded material is prepared by embedding treatment of astaxanthin, lutein and rosemary extract with β-cyclodextrin and gum arabic.The application significantly reduces the incidence of intestinal inflammation of California bass through the synergistic effect of fermented plant protein, pre-embedded antioxidant combination and microcapsule sodium butyrate, enhances antioxidant capacity, improves body color, improves the stability of active ingredients and feeding rate, and realizes low morbidity under antibiotic-free breeding conditions.

The present application relates to the technical field of animal breeding, and discloses a compound nutritional health supplement for laying hens in the egg production period and a preparation and application thereof, which comprises the following raw materials in mass fractions: motherwort 1200-1400 parts, radix astragali 150-250 parts, radix codonopsis 80-120 parts, betaine hydrochloride 500-700 parts, butyric acid clostridium 50-70 parts, bacillus licheniformis 90-110 parts, vitamin acetate 3-5 parts, coated 25-hydroxy-cholecalciferol 1-2 parts, vitamin E acetate 15-25 parts, and rice husk powder 0-411 parts. The formula can scientifically and comprehensively regulate the digestion and absorption of nutrients, immune function and reproductive system health of laying hens, improve the eggshell quality, egg weight and nutritional quality of egg products, has stable effect and strong universality, greatly reduces the side effects and body burden caused by long-term medication while ensuring the effect, and is more suitable for the concept of healthy breeding; the health level of the body is comprehensively improved, the intestinal flora balance is maintained by probiotics, the immunity and stress resistance of laying hens are overall enhanced, the nutrient utilization rate is improved, and healthy high yield is achieved.

The present invention relates to the use of D-beta-hydroxybutyrate (D-BHB) in the treatment or dietary management of a Long-Chain Fatty Acid Oxidation Deficiency (LC-FAOD), for example, in the prevention and / or amelioration of one or more symptoms associated with LC-FOAD. Additionally, the invention provides compositions comprising D-BHB as the active ingredient. These compositions may be formulated as pharmaceutical compositions or nutritional compositions, such as Foods for Special Medical Purposes (FSMPs).

The present application provides a soluble dietary fiber composition, its preparation method and application. After the soluble dietary fiber composition enters the colon, the ester bond in the alanine modified pectin is rapidly degraded, part of the chlorogenic acid is released, the secretion of anorectic hormone is stimulated, the appetite is reduced, and the heat intake is reduced; the remaining amide bond network is slowly degraded, realizing the slow and continuous release of chlorogenic acid. Lutein removes free radicals generated by fat decomposition, reducing the oxidative damage of L cells. Galactomannan and alanine modified pectin-glucan modified protein-chlorogenic acid ternary complex synergize to improve the molar ratio of butyric acid / propionic acid: propionic acid enhances satiety through intestinal gluconeogenesis, and butyric acid stimulates the secretion of GLP-1 / PYY, realizing endogenous appetite suppression. Galactomannan absorbs water to form a lubricating gel, softening the stool and increasing the stool volume; the ternary complex degrades to produce short-chain fatty acids, optimizing the intestinal microenvironment and enhancing gastrointestinal peristalsis, both of which synergistically improve constipation.

The present invention relates to the use of D-beta-hydroxybutyrate (D-BHB) in the treatment or dietary management of a Long-Chain Fatty Acid Oxidation Deficiency (LC-FAOD), for example, in the prevention and / or amelioration of one or more symptoms associated with LCFOAD. Additionally, the invention provides compositions comprising D-BHB as the active ingredient. These compositions may be formulated as pharmaceutical compositions or nutritional compositions, such as Foods for Special Medical Purposes (FSMPs).

This invention discloses an instant gelling powder of sodium alginate / calcium β-hydroxy-β-methylbutyrate with dual functions of fat reduction and muscle gain, and its application, belonging to the field of functional food or pharmaceutical preparation technology. The powder of this invention is prepared by dry mixing sodium alginate and CaHMB at a weight ratio of 5~10:1~5, preferably 7:3, wherein the guluronic acid content of sodium alginate is ≥50%. In use, 1g of powder is added to 20~40mL of water at 60~100°C, and stirred to form a hydrogel. After oral administration, the powder rapidly forms a gel in the stomach, producing a feeling of fullness, and simultaneously achieves fat reduction, muscle gain, and metabolic regulation functions by regulating myostatin expression. This invention overcomes the limitation of existing weight management products with only one function, innovatively integrating the three major effects of instant satiety, fat reduction, and muscle gain. The preparation process is simple and environmentally friendly, requiring no added chemical excipients, and has significant technological advancement and market application value.

The present invention addresses the problem of providing technology that can reduce off-flavors derived from free medium-chain fatty acids in aqueous-phase-containing foods containing triglycerides that contain medium-chain fatty acids as constituent fatty acids.　The present invention provides a food composition, said food composition comprising an oil phase and aqueous phase and comprising a prescribed amount of one or more components selected from the group consisting of allyl isothiocyanate, 1-hexanol, 2-heptanone, and butyric acid, wherein the oil phase contains a medium-chain fatty acid, and the medium-chain fatty acid is in the form of a triglyceride constituent fatty acid and / or in the form of a free medium-chain fatty acid.

The application discloses a kind of compound probiotic propagation methods and application, including the following steps: S1, in culture solution inoculation clostridium butyricum species carries out first fermentation, obtains first fermentation liquor;S2, inoculation lactobacillus plantarum species and Enterococcus faecium species carry out second fermentation, obtain second fermentation liquor;S3, inoculation yeast fungus species carries out third fermentation, obtains compound probiotic propagation liquor.The compound probiotic propagation liquor obtained in the application is added to pig feed for feeding, which can significantly improve the production performance of different pig groups, improve the skin redness and hair gloss of pig groups, increase the feed intake of pig groups, and reduce the breeding cost.

This invention discloses a probiotic protein V2016 and its application in the preparation of drugs for treating obesity, belonging to the field of biomedical technology. This invention provides a probiotic protein V2016, the amino acid sequence of which is shown in SEQ ID NO.1. Verification has shown that protein V2016 can efficiently and stably bind to the intestinal receptor ICAM-2, thereby significantly upregulating GLP-1 expression, mediating weight loss, reduced fat accumulation, and improved glucose tolerance; simultaneously, it can also reduce hepatic lipid deposition and inflammation, and promote thermogenesis activation in adipose tissue; at the intestinal microecological level, protein V2016 can improve the intestinal microenvironment, promote the enrichment of butyrate-producing bacteria in the intestine, thereby playing a role in regulating metabolism. In summary, the protein V2016 provided by this invention can be applied to the development of novel functional foods or weight-loss drugs.

This invention provides an animal feed prepared using microbial fermentation products and its preparation method. By constructing a symbiotic community of anaerobic ammonia-oxidizing bacteria and Clostridium butyricum, and combining it with livestock and poultry manure biochar as a fixation carrier and a complex enzyme system, the protein degradation and nitrogen emission control of ruminant feed are optimized. This method degrades crude protein into small peptides through anaerobic fermentation, while simultaneously converting ammonia nitrogen into nitrogen gas, effectively reducing ammonia emissions by 70%-80%. Furthermore, the use of high-temperature activated biochar as a fixation carrier improves the colonization rate and stability of the microbial community. This invention not only improves the nutrient utilization rate of feed but also solves the problems of high nitrogen emissions and low fiber utilization in traditional feeds, providing a novel solution for low-nitrogen, environmentally friendly ruminant feed.

The purpose of the present invention is to provide a new means for increasing the butyric acid concentration in the intestine. Provided is a composition containing a human milk oligosaccharide and Heyndrickxia coagulans.

The application discloses a liver injury model special for Hugan Buzu re granules and a construction method thereof, and belongs to the technical field of animal models, which comprises an animal model main unit, a dynamic data acquisition and processing unit and a comprehensive efficacy prediction unit, wherein the dynamic data acquisition and processing unit is configured to collect and process fecal and serum samples at an early time point after intervention of the Hugan Buzu re granules, and output an early characteristic vector composed of characteristic values including a relative abundance change rate of lactobacillus and akkermansia, a serum CA / DCA ratio and a butyric acid concentration; the comprehensive efficacy prediction unit integrates a stacking integrated prediction model of a solidification parameter, and can directly predict and output a comprehensive efficacy score representing the Hugan Buzu re granules at a preset efficacy endpoint; and the application has made significant progress in the speciality of evaluation, the foresight of prediction and the robustness of the method, and provides an innovative solution for precise and efficient research and development of liver-protecting drugs.

The application belongs to the technical field of biological medicine, and provides a composition for preventing and improving cancer and sarcopenia caused by related treatment and immunodeficiency, a preparation method and application thereof.The composition comprises the following components: nucleotides, beta-hydroxy beta-methyl butyrate, arginine, histidine, glutathione, fish oil, seaweed oil and vitamin E.The composition has remarkable effects on improving cancer and sarcopenia caused by related treatment and immunodeficiency in the compounding of the components.

The present application relates to the field of asexual reproduction technology, and more particularly to a method for large-scale cultivation of seedlings by using pineapple waste stem in field. The method comprises the following steps: after harvesting of pineapple fruits, collecting healthy above-ground stems of pineapple, removing leaves and residual fruit stalks, and soaking the base of the stems in a composite pretreatment solution for 25-35 minutes; immersing the pretreated stems in an indole butyric acid solution for 8-15 seconds; ridging, ditching on the ridge surface, and inserting the stems into the ditch at an angle of 35-45 degrees with the bud eye facing upwards, with 2 / 3 of the length of the stems being buried in the soil and the remaining part being exposed to the ground; pouring water thoroughly after insertion, controlling the light intensity, maintaining the soil temperature at 20-30 DEG C, and culturing for 45-60 days; when the newly grown seedlings grow to 15-25 cm, gradually increasing the light intensity for 7-10 days of seedling hardening, and taking out the stems together with the base when the seedlings are transplanted, and obtaining the seedlings after separation. The present application converts waste stems into seedlings, and realizes in-situ resource utilization of waste.

The present application belongs to the technical field of biological medicine, and particularly relates to a composition for improving cognitive function, a preparation method, products and applications thereof. The composition is prepared from soybean meal powder, whey protein peptide powder and bovine collagen peptide powder in a mass ratio of 1:3:2 as a peptide source raw material, in combination with AMY001, Lactobacillus plantarum LP-90 and Clostridium butyricum (3:1:1) composite strains, through Bacillus amyloliquefaciens enzyme production self-digestion, peptide-bacteria anaerobic synergistic fermentation and sodium alginate-HPMC-CPP composite carrier embedding. The composition can work synergistically through multiple mechanisms such as clearing hippocampal Aβ1-42 protein, increasing BDNF content and inhibiting IL-6 expression, has high memory improvement rate and Aβ1-42 clearance rate, and can significantly repair cognitive impairment. The composition has high stability and bioavailability, the preparation process is controllable, and is suitable for the development of drugs for preventing or assisting in improving cognitive impairment related diseases.

The application discloses a compound lactic acid bacteria additive for improving the quality of corn straw-sweet potato vine compound silage and application thereof, and belongs to the field of feed processing. The compound lactic acid bacteria additive comprises the following components in parts by weight: 0.5-1.5 parts of lactobacillus plantarum and 0.8-1.2 parts of lactobacillus buchneri. The compound lactic acid bacteria additive can significantly improve the crude protein content of corn straw-sweet potato vine compound silage, promote the degradation of fiber components to improve the digestion and utilization rate, quickly reduce and maintain the low pH value of the silage, reasonably accumulate lactic acid, inhibit the generation of butyric acid and the accumulation of ammonia nitrogen, maintain a high propionic acid content to prolong the aerobic stable period of the feed, and has better effects than traditional silage additives in terms of fiber degradation, protein retention, fermentation environment regulation and the like, so that the research blank of the special additive for the compound raw material silage is filled, and the resource utilization of agricultural wastes is realized.

This invention discloses a method for producing 1,3-propanediol by fermentation using glycerol and starchy raw materials as co-substrates, belonging to the field of microbial fermentation technology. This invention uses *Clostridium butyricum* DL07 as the production strain, glycerol as the main carbon source, and adds corn starch, rice flour, or refined rice flour as auxiliary substrates, conducting batch or fed-batch fermentation under anaerobic conditions. This invention solves the technical problems of high cost, sugar metabolism repression effect, and unreasonable byproduct distribution associated with using pure sugar as an auxiliary substrate in existing methods. By directly adding inexpensive starchy raw materials, it reduces the sugar metabolism repression effect, improves glycerol conversion rate, optimizes byproduct composition, and reduces raw material costs. The starchy raw materials used in this invention do not require enzymatic pretreatment, making them suitable for industrial production and significantly reducing the production cost of glycerol bioconversion to 1,3-propanediol.

The application provides a Clostridium efficient culture medium based on yellow water, a culture method, a preparation and an application. The yellow water culture medium comprises 20%-40% of yellow water, a byproduct of liquor brewing, and the rest is deionized water, and the pH value is adjusted to 6.5-7.5. The method for culturing Clostridium from pit mud source comprises the following steps: after the culture medium is sterilized, Clostridium from pit mud source is inoculated at an inoculation amount of 5%-15%, and then the mixture is placed and cultured anaerobically at 35-37 DEG C for 24-100 hours. The yellow water is converted into an efficient special culture medium for Clostridium, which can significantly promote the growth and proliferation and metabolic activity of Clostridium from pit mud source at the same time. Not only high-biomass Clostridium culture can be obtained, but also a breakthrough can be made to activate and support various Clostridium from pit mud source to synthesize organic acids such as hexanoic acid and butyric acid. The Clostridium culture rich in organic acids and the functional microbial preparation comprising the Clostridium culture can be used for strengthening liquor fermentation, maintaining pit mud or constructing artificial pit mud, and the high-value utilization of the byproduct of liquor brewing is realized. The cost is low, and the effect is remarkable.

The present application relates to the technical field of feed, and discloses a compound feed formula for improving survival rate of egg chicken chicks, which comprises the following components in parts by weight: energy feed component: corn 400-550 parts, puffed corn 150-250 parts, and bean oil 5-15 parts; protein feed component: soybean meal 150-250 parts, puffed soybean 50-100 parts, fish meal 10-30 parts, and fermented soybean meal 20-60 parts; mineral and amino acid component: stone powder 10-20 parts, calcium hydrogen phosphate 10-20 parts, salt 2-5 parts, methionine 1.5-3 parts, lysine 1-2.5 parts, and choline chloride 1-2 parts; functional additive component: compound probiotics 1-5 parts, compound enzyme preparation 0.5-2 parts, compound acidifying agent 1-4 parts, compound vitamin 0.3-1 part, and compound trace element 0.5-1.5 part; the three probiotics of Clostridium butyricum, Bacillus subtilis and Saccharomyces boulardii are compounded according to specific proportions, and the three strains form a segmented relay synergistic mode, so that comprehensive health maintenance is realized from the whole length of the intestinal tract.

The present invention relates to a feed composition for preventing or improving chronic enteropathy and adverse dietary reactions, wherein, according to one aspect, the feed composition for preventing or improving chronic enteropathy and adverse dietary reactions may include omega-3 fatty acids and butyric acid.

The application discloses a detection method for simultaneously determining the content of seven main volatile flavor components in maca, wherein the main volatile flavor compounds include acetic acid, benzaldehyde, butyric acid, ethyl phenylacetate, phenylacetonitrile, benzyl isothiocyanate and 3-methoxyphenylacetonitrile; the flavor substances in the maca are extracted by using a 95% ethanol ultrasonic extraction method, the quantitative determination is carried out by using an internal standard curve method, and the analysis is carried out by using a gas chromatograph mass spectrometer. The application has the advantages of less interference, low detection limit, high response value, wide detection range and high accuracy.

Provided are a biological patch, a preparation method therefor, and use thereof. The biological patch is a fish skin-based biological patch, and contains a first fatty acid and a second fatty acid. A mass percentage of the first fatty acid in the biological patch is greater than or equal to 1.4%, and a mass percentage of the second fatty acid in the biological patch is less than or equal to 2.0%. The first fatty acid includes at least two of butyric acid, caprylic acid, lauric acid, myristic acid, pentadecanoic acid, etc. The second fatty acid includes an ω-6 unsaturated fatty acid. The biological patch includes collagen fibers with a certain diameter, and the biological patch includes micropores with a certain pore size and a certain porosity. The preparation method for the biological patch includes degreasing, pigment removal, and decellularization. The obtained biological patch is used for repairing soft tissue or used as a skin repair dressing. The biological patch can reduce or eliminate inflammatory response of an administration site, and exhibit good mechanical performance and degradation performance.

The application discloses a kind of special feed additive compositions of pig, preparation method and use method, the additive composition of the application includes microecological function component (metabiotic and probiotic bacteria), enzyme preparation component (non-starch polysaccharide enzyme, protease, lipase), plant active component (tannic acid and plant essential oil), organic trace element and nutrition fortification component (amino acid chelated trace element, functional amino acid, nucleotide yeast hydrolysate) and targeted acidifier (citric acid, lactic acid, butyric acid glyceride).The special feed additive composition of pig proposed in the application can make the average daily weight gain of pig reach 338g / d, increase by 50.9% compared with prior art, the standard rate of piglet weaning is increased to 85%, the feed conversion ratio is reduced to 2.31, the diarrhea incidence is reduced to 5.0%, with significant growth promotion, intestinal repair, feed conversion efficiency improvement and environmental pollution reduction benefits.