5 results about "Thromboplastin" patented technology

The present invention relates to a method for producing thrombin from a thromboplastin source using a given BaSO4 reagent as an adsorbent for prothrombin, and a method for assessing the suitability of a given BaSO4 reagent for the preparation of thrombin. In at least one embodiment, the method comprises contacting a sample of the given BaSO4 reagent with a thromboplastin source to obtain BaSO4-adsorbed thromboplastin, and subsequently assessing the procoagulant activity of the BaSO4-adsorbed thromboplastin. In another embodiment, the method comprises the step of assessing the procoagulant activity relative to normal mammalian plasma.

The invention belongs to the technical field of biological medicines, and particularly relates to a cyclic polypeptide CycSD6 of a targeted contact kinin system and application of the cyclic polypeptide CycSD6. The cyclic polypeptide CycloSD6 provided by the invention comprises an amino acid sequence as shown in SEQ ID NO: 1; the head and the tail of the amino acid sequence as shown in SEQ ID NO: 1 form a ring through an amido bond. The head and tail amido bonds of the amino acid sequence as shown in SEQ ID NO: 1 are cyclized, the plasma stability of the straight-chain polypeptide as shown in SEQ ID NO: 1 can be improved, and compared with the straight-chain polypeptide, the cyclized cyclic polypeptide has the advantages that the inhibitory activity on plasma kallikrein and blood coagulation factor XIIa is further improved, the plasma recalcification time and the partial thromboplastin activating time can be prolonged, and the blood coagulation factor XIIa can be inhibited. The compound has good anti-thrombus and cerebral apoplexy activity effects, does not cause hemolysis and bleeding risks, and is low in cytotoxicity and high in safety.

A method for controlling MNPT is required.Coexistence of a specific metal ion with tissue thromboplastin enables MNPT to be controlled / adjusted to a desired time. Coexistence of the specific metal ion with tissue thromboplastin also enables improvement of stability when a thromboplastin reagent is stored in a solution form.

The present invention discloses a prothrombin time detection reagent and a preparation method thereof. Among them, the prothrombin time detection reagent is prepared from rabbit brain powder, a solvent, sodium chloride, a surfactant, a metal salt, a reducing agent, and calcium chloride. It can effectively remove coagulation factor VII, so that the prepared thromboplastin does not contain coagulation factor VII, making the prepared prothrombin time detection reagent highly sensitive to coagulation factor VII, ensuring the detection accuracy and improving its actual use effect.

1. Name of the product in this design: Ultrasonic Guided Wave Thromboplastin Detector. 2. Purpose of this design: For the detection of coagulation and fibrinolysis processes and platelets. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key features: the front view.