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481 results about "Screening test" patented technology

A screening test is used to examine an individual for a disease or a health disorder. Most screening tests are done in an effort to catch a disease in its earliest stage, preferably before the onset of symptoms.

External diagnostic reagent kit used for measuring activated partial thromboplastin time

The invention relates to an in vitro diagnostic kit for the determination of activated partial thromboplatin time (APTT) in clinical test. The invention consists of a partial thromboplatin reagent and a calcium chloride solution, which is used for the detection of the defects of the intrinsic coagulation pathway factors and the screening test of the related inhibitors, and the invention is also a primary means for the current coagulation factor and heparin anticoagulant treatment and the detection of lupus anticoagulant. The invention has the advantages of long stability time and good repeatability of the partial thromboplatin reagent after a re-dissolution, at the same time, the invention has better consistency of the measurement results of a blood coagulation analyzer by using an optical method and a magnetic bead method, therefore, the invention is applicable to large, medium and small hospitals, and the test results of different hospitals have comparability, therefore the invention has important meaning for implementing the one general report of test reports, provides the reliable experimental data for the clinical diagnosis and the treatment of diseases and improves the efficiency and value of the basic studies of thrombosis and hemostasis.
Owner:SHANGHAI SUNBIO TECH

Luminescence-based methods and probes for measuring cytochrome P450 activity

The present invention provides methods, compositions, substrates, and kits useful for analyzing the metabolic activity in cells, tissue, and animals and for screening test compounds for their effect on cytochrome P450 activity. In particular, a one-step and two-step methods using luminogenic molecules, e.g. luciferin or coelenterazines, that are cytochrome P450 substrates and that are also bioluminescent enzyme, e.g., luciferase, pro-substrates are provided. Upon addition of the luciferin derivative or other luminogenic molecule into a P450 reaction, the P450 enzyme metabolizes the molecule into a bioluminescent enzyme substrate, e.g., luciferin and / or luciferin derivative metabolite, in a P450 reaction. The resulting metabolite(s) serves as a substrate of the bioluminescent enzyme, e.g., luciferase, in a second light-generating reaction. Luminescent cytochrome P450 assays with low background signals and high sensitivity are disclosed and isoform selectivity is demonstrated. The present invention also provides an improved method for performing luciferase reactions which employs added pyrophosphatase to remove inorganic pyrophosphate, a luciferase inhibitor which may be present in the reaction mixture as a contaminant or may be generated during the reaction. The present method further provides a method for stabilizing and prolonging the luminescent signal in a luciferase-based assay using luciferase stabilizing agents such as reversible luciferase inhibitors.
Owner:PROMEGA CORP

Method for testing high-temperature breaking limit of antiskid brake control box

Disclosed is a method for testing a high-temperature breaking limit of an antiskid brake control box. Three comprehensive testing devices are used for conducting a test, under a high-temperature stepping condition, antiskid brake working currents are applied, whether the performance of the antiskid brake control box is qualified or not is tested, if not qualified, improvement suggestions are put forward so that the high-temperature resistance of the antiskid brake control box can be improved, and if qualified, the test continues until required high-temperature resistance is achieved. A high-temperature stepping test belongs to accelerated life tests, test data of the high-temperature breaking limit are used as one of the bases for formulating the profile of a high-acceleration stress screening test. According to the method for testing the high-temperature breaking limit of the antiskid brake control box, the method with the high-temperature stepping test and the applied working currents integrated is used for stimulating high-temperature fault potential risks of the antiskid brake control box, the improvement suggestions directing at the fault potential risks are put forward and carried out, and the high-temperature breaking limit needed by the accelerated life tests and the high-acceleration stress screening profile is determined.
Owner:XIAN AVIATION BRAKE TECH

Method for extracting oil in steam stimulation in single well by combining microorganisms and CO2 in heavy oil well

The invention belongs to the technical field of tertiary oil recovery and particularly relates to a method for extracting oil in single well steam stimulation by combining microorganisms and CO2 in the heavy oil well. The method comprises the following steps: (1) screening test oil wells; (2) screening microorganisms and nutrients thereof; (3) injecting the microorganisms and the nutrients thereof into the stratum of the test oil well; (4) injecting liquid CO2; (5) shutting the test oil well down; (6) opening the test oil well for production. The method disclosed by the invention has the advantage of wide application range and is simple in process implementation; oil well sand production and sleeve damage situations are avoided and the oil well utilization rate is high; the thickened oil viscosity can be greatly reduced, the oil-water interfacial tension is reduced, the stratum energy can be effectively replenished, the characteristics of long action period, remarkable enhanced production effect of oil, and the like are achieved, and therefore, the method is an economic and effective method for increasing the yield of the heavy oil well and can be widely applied to a single well steam stimulation technology of the heavy oil well.
Owner:CHINA PETROLEUM & CHEM CORP +1

Gravel geometric feature acquisition system and acquisition method

The invention discloses a gravel geometric feature acquisition system and an acquisition method. A plane mirror assembly and a video camera are used for obtaining real gravel geometric features, and a gravel three-dimensional model is received according to the three-dimensional reconstruction technology, and the gravel geometric feature acquisition system and the acquisition method are used for obtaining the gravel geometric features and gradation characteristics. The main structure of the system comprises a retroreflector surface group, a video camera, and a computer. A picture is received by shooting at the gravels between the two mirrors and images reflected in the mirror, the images are inputted into the computer through a data line, the geometric features of rock fragments are gained through a three-dimensional reconstruction algorithm, and the three-dimensional model is established. The gravel geometric feature acquisition system and the acquisition method have the advantages that the geometrical features data of gravels are obtained, the granular real shape is restored, the shortcoming that a traditional screening test can only determine the minimum grain size is overcome. The gravel geometric feature acquisition system and the acquisition method are capable of meeting the accuracy requirements of the gravel granularity analysis, and of carrying out a plurality of stress deformation analysis by establishing a model combined with a discrete element software analysis technology.
Owner:ZHEJIANG UNIV
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