The invention discloses a medical adhesive, comprising the following substances in parts by weight: 65-80 parts of alpha-N-butylcyanoacrylate, 5-8 parts of hydroxypropyl methacrylate, 3-5 parts of sulfur dioxide, 1-2 parts of hydroquinone, 0.5-2 parts of polyurethane, 0.5-1.5 parts of agar, 0.8-1.2 parts of fibrin glue, 2-3 parts of water soluble phenol-formaldehyde resin, and 20-25 parts of deionized water. The medical adhesive has the beneficial effects that the medical adhesive provided by the invention is low in thrill, and excellent in bonding persistence; compared with the traditional common adhesive, the persistence of the medical adhesive can be up to 1.5-3 times; and animal experiments show that the toxic and side effects are small.