161results about How to "Rapid hemostasis" patented technology

The invention relates to a mussel-like polylipoic acid-based hydrogel adhesive as well as a preparation method and application thereof, and the preparation method comprises the following steps: (1) uniformly mixing a sericin solution and a caffeic acid solution, then carrying out grafting reaction to obtain a reaction solution, and carrying out dialysis treatment and drying on the reaction solution to obtain sericin grafted caffeic acid; (2) adding lipoic acid into the lithium hydroxide solution, stirring until the lipoic acid is completely dissolved, then adding sericin grafted caffeic acid, and heating for reaction to obtain a PTALi-CAS mixture; and (3) cooling the PTALi-CAS mixture, so as to obtain the mussel-like polylipoic acid-based hydrogel adhesive. The dual-network PTALi-CAS hydrogel adhesive obtained in the invention realizes wet adhesion and rapid hemostasis, has excellent comprehensive performance, and is beneficial to providing a good repair environment for wounds as a wound dressing.

The invention relates to an antibacterial and hemostatic composite material and a preparation method thereof. The preparation method comprises the following steps: reacting exfoliated graphene oxide with KH560 at 60 DEG C to obtain coupled grafted graphene oxide EGO; then under the condition of intense stirring at 80 DEG C, enabling the kaolin nanotube to react with EGO (Ethylene Gallate Oxide), so as to obtain EGO-EK; and then reacting the chitosan solution with EGO-EK by using a cross-linking agent and a catalyst to obtain a uniform suspension, and freeze-drying. The hemostatic composite material disclosed by the invention has the advantages of bacterial infection resistance, difficulty in tissue adhesion with a wound surface, good mechanical property, photo-thermal effect, excellent biocompatibility and rapid hemostatic capability, and in addition, the hemostatic composite material can accelerate the healing of the bacterial infection wound surface.

The invention discloses a preparation method and application of photo-thermal antibacterial hydrogel for MRSA (Methicillin Resistant Staphylococcus Aureus) infected diabetes wounds, and relates to the technical field of biological tissue engineering. The method comprises the following steps: uniformly dispersing ZIF-8 (at) PDA nanoparticles in a carboxymethyl chitosan solution, adding a gelatin solution, uniformly mixing, adding into an oxidized sodium alginate solution, and carrying out a Schiff base reaction to obtain the photo-thermal antibacterial hydrogel for MRSA infected diabetes wounds. The hydrogel disclosed by the invention is prepared by crosslinking carboxymethyl chitosan, gelatin, oxidized sodium alginate and dopamine modified ZIF-8 nanoparticles through a Schiff base bond. Carboxymethyl chitosan (CMCS) has excellent biocompatibility, antibacterial activity and adjustable and controllable mechanical properties, and can effectively preserve moisture, form a breathable and moist environment and promote skin healing.

The invention belongs to the technical field of regenerated medical dressings, particularly relates to a plant polysaccharide hydrogel medical dressing for promoting tissue damage repair and application thereof, and provides the following scheme that a medical and mechanical combined product comprises a regenerated medical dressing and a low-temperature sterile storage box for storing the regenerated medical dressing, the regenerated medical dressing comprises a hydrogel main body, open pores formed in the hydrogel main body, sustained-release vesicles arranged in the open pores, and stem cells and a cell culture medium which are filled in the sustained-release vesicles. The stem cell hydrogel can rapidly break blood, rapidly stop bleeding by being attached to a wound surface and promote wound closing, stem cells are inoculated to the upper surface of the hydrogel formed by dendrobium polysaccharides, aloe, lily, coptis chinensis and honeysuckle, safe application of the stem cells is achieved, active factors secreted by the stem cells are slowly released to the skin wound surface, and the wound healing effect is achieved. Through contact stimulation between cells, various cytokines can be secreted better, and the skin repair efficiency is improved.

The invention discloses a preparation method and application of a marine high-molecular polysaccharide hydrogel wound dressing. The hydrogel is formed by cross-linking the marine polysaccharide composition and the cross-linking agent, and the gelation time is short and is about 15 seconds; pores are uniform and moderate; the self-healing property, the adhesion property and the swelling property are high; the antibacterial effect is strong, and the inhibition rates on escherichia coli and staphylococcus aureus are both higher than 90%; skin irritation and skin allergy are avoided, and the biological safety is high; hemostasis can be rapidly carried out within 10s, and the bleeding amount is obviously reduced; the hydrogel dressing can rapidly shrink and scab a wound surface, has the effect of promoting wound healing, and has the effects of stopping bleeding and promoting wound healing which are obviously superior to those of commercially available hydrogel dressings (German Hydrosorb Gel) (Plt; 0.05), and is a safe and effective high-performance wound dressing. In addition, the hydrogel is simple in formula and high in industrialization prospect, is expected to be developed into novel wound dressings and medical instruments, and breaks through the trapping that domestic hydrogel dressings are mostly dependent on import.

The invention discloses a preparation method of a composite spray for improving the hemostatic ability of a wound part, the composite spray comprises a liquid A and a liquid B. The liquid B is a sodium alginate aqueous solution, a preparation method of the solution A comprises the following steps: 1, dissolving a lipopeptide conjugate, cholesterol, distearoyl phosphatidylcholine, distearoyl phosphatidylserine and dimethyl sulfoxide in a chloroform-methanol mixed solution to obtain a mixed system; 2, preparing the mixed system into a precursor solution by utilizing a film hydration method; 3, adding calcium chloride into the precursor solution, and reacting in a dark place to obtain a solution A; a precursor solution is designed according to the function of natural platelets, the function of the precursor solution is equivalent to that of nano platelets, the precursor solution is matched with sodium alginate, adverse effects on a blood coagulation system caused by fibrin degradation, platelet activation capability reduction and the like of a wound part due to blood loss can be relieved in a targeted manner, and the preparation has the advantages of rapid hemostasis, good biological activity, no toxic or side effects and the like. And the wound healing is rapid.

The invention discloses recombinant human XVII type collagen with a hemostasis function and application of the recombinant human XVII type collagen. The recombinant human XVII type collagen is a truncated protein of the human XVII type collagen, and the amino acid sequence of the recombinant human XVII type collagen is shown as SEQ ID NO: 1. The recombinant human XVII type collagen has efficient and rapid hemostatic performance, meanwhile, the recombinant collagen is easy to separate and purify, a pure product with the purity reaching 97% or above can be prepared through simple membrane separation and chromatographic separation, and the production process is easy to amplify. In the aspect of hemostasis performance, compared with commercially available products, the recombinant human XVII type collagen has the advantages that the hemostasis time is obviously shortened, and the hemostasis performance is obviously improved.

The present invention discloses an L-shaped fiber supramolecule and its preparation method and application. The structural formula of the L-shaped fiber supramolecule is shown in formula (I). The preparation method includes: activation of resin, coupling of amino acids, excision and precipitation of polypeptides, and separation and purification of polypeptides. The L-shaped fiber supramolecule prepared by the present invention has good biocompatibility, does not cause inflammatory reaction at the wound site, has the function of binding calcium ions, and exhibits excellent effects in hemostasis and bone regeneration. #imgabs0#

The invention relates to a rapid self-gelation modified gelatin-based styptic powder composition as well as a preparation method and application thereof. The styptic powder is composed of phenylboronic acid modified gelatin and a long-chain polymer containing a diol structure, and can be used independently or matched with thrombin or polyethylene glycol active derivative powder to prepare a composition for use. Under physiological conditions, the powder can rapidly absorb blood, settle and self-crosslink to form hydrogel, activate an endogenous hemostasis pathway and perform physical plugging, and rapid hemostasis is realized. When used together with thrombin, the medicine can maintain local high concentration and accelerate blood clot formation, and is suitable for emergency control of massive hemorrhage. When the hydrogel is combined with a polyethylene glycol active derivative, tissue adhesion and a dual-network structure can be realized, the gel strength is improved, and long-acting hemostasis is realized.

The invention discloses a flexible and stable three-layer porous structure hemostatic dressing and a preparation method thereof, and belongs to the technical field of biological medicine. The preparation method of the hemostatic dressing comprises the following steps: constructing a stable foaming system by using protein and polysaccharide, constructing a dual three-dimensional network by combining multi-source polysaccharide and tannic acid, and designing a large-area dressing structure by overlapping the dual three-dimensional network with cotton gauze; carrying out Ca < 2 + > cross-linking impregnation and freeze drying in a weak acid environment to prepare an integrally formed three-layer dual-network multi-source porous structure dressing; the dressing has three layers of different structures, has an extremely fast hemostatic effect, reduces the amount of bleeding, can effectively maintain the humidity of a wound, avoids invasion and infection of bacteria, and can quickly and effectively sterilize; good shape maintaining and recovering capability is realized; meanwhile, the advantages of the porous structure and the cotton gauze are integrated, the structure is enriched, the structural stability of the large-area dressing is improved, the dressing can be stored for a long time in a normal-temperature environment, and the physical basic performance of the dressing meets the requirements of medical dressings.

The invention provides a polyethylene glycol derivative. The polyethylene glycol derivative comprises a main chain with a structure as shown in a formula (IIa) and an end group with a structure as shown in a formula (IIb). According to the invention, hydroxyl and carboxyl of polyethylene glycol are directly subjected to esterification reaction to generate a polyethylene glycol derivative of which the end group is provided with o-phthalaldehyde, and finally the polyethylene glycol derivative and polyethylene glycol of which the end group is provided with amino form the chemical crosslinking hydrogel. Due to the introduction of ester bonds, the degradation time of the hydrogel is shortened, the gelling rate of the hydrogel is increased, and meanwhile, the hydrogel is high in adhesion performance, simple in preparation process and suitable for large-scale production.

The invention discloses a chitosan nanofiber-based hemostatic sponge and a preparation method thereof, and belongs to the field of dressing preparation. The chitosan nanofiber-based hemostatic sponge is mainly prepared from chitosan nanofibers, alginate, amorphous calcium salt and a cross-linking agent. The chitosan nanofiber is used as a main framework of the hemostatic sponge, and blood cells and platelets can be conveniently adsorbed due to a large number of amino groups and high porosity; due to the existence of alginate, blood clots can be conveniently formed after the hemostasis sponge absorbs blood; the existence of calcium promotes the initiation of a blood coagulation cascade reaction and synergistically accelerates the hemostasis effect. The three components are combined to complement each other, so that the hemostatic sponge has more excellent hemostatic performance, and an excellent blood coagulation and hemostasis effect is achieved after all aspects are integrated.

The invention relates to the technical field of medical auxiliary instruments, and discloses heart end compression hemostasis equipment for cardiology department, which comprises a compression hemostasis equipment main body, a hemostasis pressure regulating mechanism and a hemostasis compression pad, the hemostasis pressure regulating mechanism is arranged at the rear end of the compression hemostasis equipment main body, and the hemostasis compression pad is positioned at the bottom of the compression hemostasis equipment main body; a pressure regulating chamber is formed in the hemostasis pressure regulating mechanism, and a storage cylinder is rotationally mounted on one side of the hemostasis pressure regulating mechanism. Compression hemostasis is conducted on an artery wound of a patient through the hemostasis compression pad, when compression hemostasis is conducted within the specified time range and decompression buffering is needed, the output end of a miniature electric telescopic rod shrinks, and due to the fact that one side of the top of a limiting block is an inclined face, the limiting block automatically shrinks towards the interior of a second cavity; at the moment, the elastic force of a first spring acts on a baffle, and a second piston is driven by a first connecting rod to contract in a contraction cavity, so that the hemostasis compression pad automatically releases part of pressure, and the necessary blood supply requirement is guaranteed.

The invention provides styptic powder based on tannic acid modified gelatin as well as a preparation method and application of the styptic powder. The modified gelatin is a compound formed by chemically crosslinking and blending tannic acid and pre-crosslinked gelatin, the tannic acid can be uniformly distributed in a gelatin network, and the tannic acid serving as an exogenous hemostatic active substance can be subjected to rapid non-covalent interaction such as H bonds and pi-pi stacking with proteins in blood to form microclots; gelatin particles are promoted to rapidly infiltrate blood and settle, so that aggregation of platelets and red blood cells is accelerated, and gelatin can accelerate activation of an endogenous hemostasis pathway, so that a synergistic effect is formed, and rapid hemostasis is realized. In addition, tannic acid also has good antibacterial activity, wound infection after hemostasis can be effectively avoided, and the tannic acid is especially suitable for emergency hemostasis in outdoor first aid.

The utility model discloses a pressurizing tourniquet which comprises a tourniquet body, an air guide tube and a rubber ball. Compared with the prior art, the utility model has the advantages that: 1) rapid hemostasis: the gas filling cavity of the belt body is rapidly inflated by extruding the rubber ball, so that rapid pressurization hemostasis of a wound is realized; (2) the pressure is adjustable: the pressure in the belt body can be accurately controlled by adjusting the force for extruding the rubber ball, so that the pressurization requirements of different wounds are met; 3) firm fixation: the band body can be tightly attached to the wound through the bonding mode of the hook veneer and the loop veneer, and is not easy to loosen or fall off; 4) time is saved: the pressing time of the nurse can be obviously reduced by using the pressurizing tourniquet, so that the nurse has more time to complete other work; and (5) the risk is reduced: the risk of skin cyan and hematoma at the puncture part can be reduced through precise pressurization hemostasis.

Provided is a tunable biopolymer hydrogel produced from two processed natural polysaccharides for use as a hemostat. If desired, the hydrogel formation can be tuned so that the hydrogel forms within seconds when applied to a tissue lesion. The resulting hydrogel can adhere to tissue and, without swelling, produce hemostasis within seconds after application to tissue of interest. The hydrogel also captures, aggregates and concentrates platelets and red blood cells at the site of the tissue lesion thereby initiating a clotting cascade at the site of the lesion. The hemostat can be used to prevent blood loss during surgical procedures, for example, during brain, spine or other surgical procedures where hemostasis is desirable, and is particularly useful during surgical procedures where swelling of the hemostat (e.g., in the brain or spine) would be detrimental to the subject.

The invention discloses modified sodium alginate / quaternized chitosan self-expanding composite hemostatic powder and a preparation method thereof. The preparation method comprises the following steps: S1, preparing sodium alginate grafted dopamine through amidation reaction, dialyzing, freeze-drying and grinding into powder; s2, mixing the modified sodium alginate and the quaternized chitosan powder according to different mass ratios; s3, adding citric acid and sodium bicarbonate powder with different masses into the mixed powder, and uniformly mixing to obtain the modified sodium alginate / quaternized chitosan self-expansion composite hemostatic powder. The hemostatic powder obtained by the method has the excellent characteristics of blood-triggered expansion, fast gelation, shape self-adaption, coagulation promotion and the like, and has excellent hemostatic performance in deep irregular wounds. Compared with commercial styptic powder, the styptic powder prepared by the method is simple in preparation process, low in cost and relatively high in safety. The modified sodium alginate / quaternized chitosan self-expansion composite hemostatic powder has a great application prospect in the field of incompressible bleeding control materials.

The application provides a first-aid hemostasis robot and a control method thereof. The first-aid hemostasis robot comprises a robot main body capable of walking on the ground, a mechanical arm with multiple degrees of freedom arranged on the robot main body, a pressing head and a blocking piece arranged on the mechanical arm, the pressing head is used for pressing and hemostasis of a blood vessel of a bleeding port, the blocking piece is carried by a flexible continuum robot, a front end of the continuum robot is provided with a camera used for collecting information of a bleeding site, the blocking piece can be inserted into the inside of the bleeding port through the continuum robot and expanded after blocking the bleeding port to seal a large blood vessel of the bleeding port. The mechanical arm carries the pressing head and the blocking piece to perform hemostasis on different conditions of large bleeding respectively, if the bleeding is of a split type, the pressing head is used for pressing and hemostasis at a proximal end of an artery bleeding or a distal end of a vein bleeding, if the bleeding is of a broken type, the blocking piece is inserted into a wound through the continuum robot to seal a large blood vessel of the bleeding.

The invention relates to the technical field of hemostatic cotton, in particular to rapid hemostatic cotton with good antibacterial property and adhesion as well as a preparation method and application of the rapid hemostatic cotton. The invention discloses rapid hemostatic cotton with good antibacterial property and adhesion. The rapid hemostatic cotton is obtained by sequentially carrying out carboxymethyl treatment, tannic acid treatment and silver ion chelating treatment on cotton fabric. The rapid hemostatic cotton provided by the invention has a very high liquid absorption rate, can be rapidly gelatinized when being in contact with blood, and can be adhered to a wound, seal the wound and prevent bacteria from invading the wound, so that the purposes of rapidly stopping bleeding and promoting healing are achieved.

The application discloses a kind of protein sponges of fast hemostasis and preparation method and application thereof.The protein sponge is prepared by modified protein irradiation crosslinking, and the structural formula of the modified protein is as shown in formula I: R1 is substituted alkyl;Substituted substituent group of substituted alkyl is selected from one or more of carboxyl, carbonyl, amido, amino, ester group;R2 is group containing carbon-carbon double bond;Substitution degree of R2 is 10%~80%;Substitution degree of R1 is 5%~20%.The present application introduces carbon-carbon double bond group and hydrophilic group at the primary amine position of protein, imparts the crosslinking ability of protein and enhances the hydrophilic performance of protein, by limiting the substitution degree of R1 and R2, the rate of protein sponge gelation after water absorption is regulated, and the controllable adjustment of sponge skeleton swelling speed and sponge channel contraction is realized.Compared with existing sponge, the protein sponge of the present application has good flexibility, more excellent efficiency of enriching blood clotting components, and low risk of rebleeding.

The invention discloses a method for fixing a metal organic framework material Zn-BDC on the surface of a substrate material under the assistance of polytannic acid, which comprises the following steps: step 1, at room temperature, firstly soaking a clean substrate material in a weakly alkaline tannic acid aqueous solution, and then sequentially cleaning and drying to obtain a substrate material with the surface modified with a polytannic acid coating; 2, the substrate material with the surface modified with the polytannic acid coating is soaked in a zinc acetate solution, then cleaned and dried in sequence, then soaked in a 1, 4-sodium terephthalate solution, and then cleaned and dried in sequence; and step 3, repeating the step 2 for multiple times to obtain the substrate material modified by the metal organic framework material Zn-BDC. The method is easy to operate and environmentally friendly, Zn-BDC can be stably fixed to the surface of the substrate material, and the substrate material is endowed with good antibacterial and hemostatic performance.

The present invention relates to an external hemostasis / internal repair double-layer composite stent and its preparation and application, comprising an inner layer of radially oriented nanofiber membrane and an outer layer of chitosan sponge with a gradient pore structure. The outer layer of the sponge with a gradient pore structure in the present invention can quickly absorb blood from the wound and stop bleeding under the action of the differential capillary effect; the radially oriented fiber layer has a cell guiding effect, and the radially oriented fiber structure can realize the release of chemokines at different concentrations from the center to the edge of the wound surface, which can guide the migration of stem cells around the damaged part to the center of the wound, while promoting the growth and adhesion of fibroblasts and accelerating wound repair.

The invention discloses an abdominal cavity hemostasis device which comprises a supporting frame, a mounting plate, a winding reel, a wire pulling mechanism and a left-right guide mechanism. The mounting plate is vertically arranged on the support frame; the winding reel is mounted on the mounting plate, and a gauze strip capable of being freely pulled out is wound on the winding reel; the thread pulling mechanism is connected with the gauze strip and is used for continuously pulling the gauze strip downwards; the left-right guide mechanism is used for transversely and alternately guiding the gauze pulled down by the yarn pulling mechanism left and right, so that the gauze is stacked and laid on the surface of a bleeding spot; and the filling mechanism is used for extruding the gauze laid on the surface of the hemorrhagic spot into the wound at intervals. According to the abdominal cavity hemostasis device, the workload of medical staff can be greatly reduced, meanwhile, the filling speed can be greatly increased, and the purpose of rapid hemostasis is achieved.

The invention relates to the technical field of hemostatic materials, in particular to a hydrogel-based hemostatic sealant and a preparation method thereof.The preparation method comprises the steps that S1, an ethanol solution of 3-methyl-3H-bis aziridine-3-propionic acid is obtained; step S2, obtaining a 1-ethyl-(3-dimethylaminopropyl) carbodiimide hydrochloride solution; step S3, obtaining an activated 3-methyl-3H-bis (aziridine-3-propionic acid) solution; step S4, obtaining a mixed solution; step S5, obtaining a solution after amidation reaction; s6, obtaining a first dialysis solution and a second dialysis solution; step S7, obtaining the spongy 3-methyl-3H-bis (aziridine)-3-propionic acid-chitosan, and carrying out a step S7, step S8, obtaining a prepolymer solution; and step S9, carrying out continuous photocuring on the prepolymer solution under a preset irradiation condition for a preset fifth time length t5 to obtain hydrogel, and taking the hydrogel as the hydrogel-based hemostatic sealant. According to the present invention, the biocompatibility is provided, and effects of easy carrying, easy use and rapid and efficient hemostasis can be achieved.

The present application belongs to the technical field of medical hemostatic dressings and bandages, and particularly relates to a Duyuwei emergency hemostatic bandage, which comprises a bandage main body, the bandage main body is composed of a tight band and a dressing pad, the dressing pad is fixed to the front end of the tight band, the dressing pad is composed of an absorption area, a tablet area and a pad base layer, the absorption area and the tablet area are fixed on the pad base layer by traditional Chinese medicine glue, the absorption area is composed of Duyuwei gelatin sponge, the tablet area is composed of Duyuwei external-use tablets, and the pad base layer is composed of a medical degreasing cotton pad. A preparation method of the Duyuwei emergency hemostatic bandage comprises the following steps: Duyuwei medicinal material decoction piece component extraction, Duyuwei external-use tablet preparation, traditional Chinese medicine glue preparation, Duyuwei gelatin sponge preparation and Duyuwei hemostatic bandage preparation. The present application has the advantages of rapid hemostasis and remarkable efficacy: the Duyuwei extract, the gelatin sponge and the traditional Chinese medicine glue synergistically act to significantly shorten the hemostasis time. Animal experiments show that the average hemostasis time is short.

The invention provides antibacterial powder and a preparation method thereof, and relates to the field of traditional Chinese medicinal materials. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 15-30 parts of raw sanguisorba officinalis, 15-25 parts of coptis chinensis, 15-30 parts of golden cypress, 10-25 parts of raw rhubarb, 10-20 parts of bletilla striata, 15-25 parts of musk and 10-25 parts of pulvis fellis suis. The preparation method comprises the following steps: S1, peeling the musk, sterilizing, disinfecting, crushing and sieving to obtain musk powder; and S2, crushing and sieving the rest raw materials, adding the musk powder, and uniformly mixing. The antibacterial powder is used for trauma infection and wound healing, can wake up dormant cells, repair damaged cells, promote cell in-situ regeneration and tissue reduction and improve microcirculation, is strong in antibacterial effect, accelerates wound healing, is rapid in hemostasis and pain relief, can rapidly stop pain and bleeding, remove slough and promote tissue regeneration within 5-15 seconds, can heal fresh wounds within 24-48 hours, and does not leave scars after healing.

The invention provides a low-sensitization antibacterial wound dressing as well as a preparation method and application thereof, and relates to the technical field of medical dressings. The tea tree oil is used as an antibacterial component of the wound dressing for the first time, and the problem that allergy is prone to occurring due to the fact that silver ions are used as antibacterial agents in antibacterial dressings is solved. The novel antibacterial wound dressing is provided by improving the components and the preparation method of the wound dressing, and the wound dressing has excellent mechanical properties and biocompatibility, has a rapid hemostasis effect and can be widely applied to medical scenes. In addition, the wound dressing disclosed by the invention can also realize rapid degradation of soil microorganisms, and is green and environment-friendly.

The application provides an emergency department wound hemostasis device, and relates to the technical field of wound hemostasis. The emergency department wound hemostasis device comprises an inflation hemostasis air bag, and the lower surface of the inflation hemostasis air bag is fixedly connected with a constant-temperature film bag. When working, the second liquid pump is started, the second liquid pump extracts water in the constant-temperature water storage tank through the second liquid pipeline, the water enters the inside of the constant-temperature film bag through the fourth liquid pipeline, the temperature of the wound is ensured, meanwhile, the first liquid pump is started, the first water valve on the first liquid pipeline is opened, the water in the constant-temperature film bag is extracted through the first liquid pipeline, and finally the water enters the inside of the constant-temperature water storage tank, so that the water in the constant-temperature film bag is always in a constant-temperature state, the temperature is close to the optimum point of the thrombin reaction, the platelet aggregation and fibrin formation can be accelerated, the method is safe and efficient, the tissue damage can be minimized, and the hemostasis speed is accelerated.

The invention provides a bone wax coating gun capable of automatically filling and ejecting bone wax, which comprises a gun body, a gun head, a bone wax mechanism, a guide pipe and a control mechanism, and is characterized in that the bone wax mechanism and the control mechanism are mounted on the gun body; the bone wax mechanism is used for mounting a bone wax pipe filled with bone wax and filling the bone wax in the bone wax pipe into an inner cavity of the gun head; the rear end of the conduit is connected with the opening of the bone wax tube, and the front end of the conduit extends into the gun head; and the control mechanism is used for controlling the bone wax mechanism to extrude out the bone wax in the bone wax pipe. Therefore, the bone wax smearing gun can be used for automatically filling the bone wax, the risk of cross infection caused by manual filling is effectively avoided, the operation of one-time implantation and multiple smearing can be carried out according to the operation condition, the rapid hemostasis effect can be guaranteed, the efficiency is improved, and the operation time is shortened.

This utility model discloses a portable hemostat for vascular access bleeding, comprising: a pressure-applying component and a fixing strap; the two ends of the fixing strap are respectively installed on the two ends of the pressure-applying component; the surface of the pressure-applying component facing the fixing strap is provided with a positive compression part and two lateral compression parts, and the two lateral compression parts are symmetrically arranged along the positive compression part; a sterile adhesive layer is provided on the positive compression part and the two lateral compression parts. Through the application of this utility model, a portable hemostat for vascular access bleeding is provided. This device has the advantages of simple structure and convenient use. Through the cooperation of the positive compression part and the lateral compression parts, rapid hemostasis is achieved at the fistula rupture point or puncture needle point, and the tension of the fixing strap can be reduced, thereby improving the patient's wearing comfort.