7 results about "Ectoine" patented technology

This invention discloses a coconut oil antibacterial and deodorizing essence, its preparation method, and its application. The essence consists of: 12-50% coconut oil, 4-10% butylene glycol, 0.1-2% sodium hyaluronate, 1-5% panthenol, 2-5% lactic acid, 2-5% potassium lactate, 1.5-6% emulsifier, 0.1-0.6% 4-tert-butylcyclohexanol, 0.1-6% ectoine, 0.1-6% ergothioneine, 1-2% non-irritating preservative composition, and the remainder being pure water. The components work synergistically. Disposable sanitary products using this essence can inhibit bacteria and deodorize, soften the skin, relieve itching, improve redness, and soothe sensitivity. Washing and care products using this essence have good inhibitory effects on harmful bacteria, build a natural biological protective film on the skin surface, and have anti-inflammatory, soothing, repairing, anti-itch, and redness-reducing properties, leaving the skin moisturized and firm.

This invention provides an engineered bacterium for producing ectoine, its preparation method, and its application. The engineered bacterium is prepared using a method comprising the following steps: using *Corynebacterium glutamicum* as the starting strain, feedback inhibition by aspartate kinase LysC is relieved, the activity of the gene lysE encoding lysine efflux permease is reduced, and the ectoine synthesis gene cluster ectABC is expressed. Based on this, the activity of any one or at least two of the following—diaminobutyrate acetyltransferase EctA, pyruvate carboxylase Pyc, or aspartate kinase LysC—is enhanced, and / or the activity of any one or at least two of the following—maloquinone oxidoreductase Mqo or homoserine dehydrogenase Hom—is reduced to further increase ectoine yield.

This invention discloses a repair composition containing multiple ceramides and its preparation method, belonging to the field of cosmetic technology. The repair composition, by mass parts, comprises ceramide AP, ceramide EOP, ceramide NP, phytosphingosine, Centella asiatica extract, Portulaca oleracea extract, Hydrangea macrophylla extract, ectoine, and tripeptide-1. This invention utilizes multiple ceramides and phytosphingosine to biomimetically replenish the lipids of the stratum corneum, combined with the synergistic effects of various plant active ingredients and active peptides, to effectively achieve multiple effects such as skin barrier repair, soothing and anti-inflammatory properties, and anti-allergy. This invention also provides a barrier repair serum containing this repair composition and its preparation method. The serum has stable physicochemical properties and, verified by in vitro cell experiments and human efficacy tests, can rapidly repair damaged skin barriers, improve sensitive symptoms such as redness and stinging, and is gentle and non-irritating, suitable for daily skincare use by people with sensitive skin and damaged skin barriers.

This invention relates to the field of separation and purification technology, and in particular to a method for separating and purifying ectoine from fermentation broth. This invention provides an integrated purification process combining aqueous two-phase extraction technology with antisolvent-temperature coupled crystallization technology, which can solve the problems of poor selectivity in separating ectoine from impurities and difficulty in controlling the crystallization process, ultimately achieving a balance between high yield (≥95%) and high purity (≥99.5%).

This invention provides an engineered bacterium for producing ectoine, its preparation method, and its application. The engineered bacterium is prepared using the following steps: using Corynebacterium glutamicum as the starting strain, feedback inhibition of aspartate kinase LysC is relieved, the activity of the gene lysE encoding lysine efflux permease is reduced, and the ectoine synthesis gene cluster ectABC is expressed; based on this, the activity of any one or at least two combinations of aspartate semialdehyde dehydrogenase Asd, aspartate transaminase AspB, or 6-phosphogluconate dehydrogenase Gnd is enhanced to further increase the yield of ectoine.

This invention provides a method for synthesizing ectoine using moderately halophilic bacteria through fermentation. It innovatively introduces a concentration reaction system, integrating the "cultivation + concentration" of halophilic bacteria into one process. This eliminates the traditional steps of batch feeding and concentration, greatly increasing the yield and efficiency of ectoine synthesis. It enables inexpensive wild-type halophilic bacteria to achieve a level comparable to that of expensive genetically engineered halophilic bacteria, thus significantly reducing the cost of ectoine synthesis.

The present application provides an oil control composition and use thereof. It is found in the present application that ectoine has a significant inhibitory effect on sebum production caused by linoleic acid. Therefore, ectoine can be used as an oil control active ingredient.