20 results about "Syringic acid" patented technology

The present application belongs to the field of biopharmacy, and particularly relates to a phenolic acid composition and application thereof in promoting digestion. The present application firstly finds a single phenolic acid for improving dyspepsia through single-component phenolic acid experiments, then attempts to find a phenolic acid compound with a synergistic effect through compounding, and surprisingly, the combination of two phenolic acids with the best effect on promoting digestion cannot achieve the best effect optimization, but eugenol with the worst effect on promoting digestion achieves a synergistic effect on promoting digestion through compounding with other phenolic acids, and can achieve the effect of a positive drug, which provides a potential alternative drug for improving dyspepsia.

The present application relates to a kind of Huahong composition effective part extract and its preparation method, the Huahong composition effective part extract includes the following components: syringic acid, new chlorogenic acid, deacetyl carlina acid methyl ester, geniposidic acid, N-acetyl-L-tyrosine, fraxidin, 4-pyridoxinic acid, 7,8-dihydroxy-4-methyl coumarin, chlorogenic acid, ferulic acid;The total content of above components is 80%-95% of effective part extract.The Huahong composition effective part extract of the present application is from the effective part of Huahong composition.

The invention discloses an upatinib eutectic crystal form as well as a preparation method and application thereof, and belongs to the technical field of medicinal chemistry. The invention provides an eutectic crystal form I formed by upatinib and vanillic acid and an eutectic crystal form G formed by upatinib and syringic acid, which have definite and reproducible characteristic X-ray powder diffraction pattern and melting point, have excellent solubility in an aqueous medium, do not generate crystal form transformation after being stored for 1 month under the condition of relative humidity of 40 DEG C / 75%, and can be used for preparing a crystal form of upatinib. And the stability is good. The preparation process route is short, the operation condition is mild, the used solvent is conventional, the target eutectic can be efficiently and repeatedly obtained, the defects that some existing eutectic preparation processes are complex, long in period or harsh in condition are overcome, and the method has good process amplification and industrialization prospects.

The application discloses a night work activating composition containing multiple plant extract, which comprises the following components in mass: 3-5 parts of extract A, 10-15 parts of extract B, 2-4 parts of extract C, 1.5-3 parts of curcumin nano-liposome, 2-5 parts of lactobacillus fermentation filtrate, 1-3 parts of lock water magnetite, 0.1-0.3 parts of xanthan gum / acrylate compound thickening agent and 0.5-1 part of preservative composition. The night work activating composition containing multiple plant extract of the application is compounded by extract A with methyl jasmonate as a target component, extract B with rhodioside and syringic acid as target components and curcumin nano-liposome, compared with the same kind of products on the market, the antioxidant and anti-glycation capacity of the night work activating composition can be targetedly strengthened, the transdermal efficiency is improved, and the DNA repair effect and anti-inflammatory effect are improved.

The invention relates to a method for the selective electro-oxidative fragmentation of lignin using an electrochemical system, comprising the following steps: (i) synthesis of a nickel-cobalt electrocatalyst; (ii) obtaining an anode coated with the electrocatalyst; and (iii) selective fragmentation and oxidation of solubilised lignin in an electrochemical reactor comprising said anode, in which vanillic acid and syringic acid are obtained as preferred products.

The application discloses a preparation method of a eugenol-based aromatic dibasic acid and application thereof. The preparation method comprises the following steps: heating and refluxing reaction of chloroacetic acid and eugenol in an alkaline solution, acidification to obtain a crude product after the reaction is completed, and obtaining the eugenol-based aromatic dibasic acid after post-treatment of the crude product. The eugenol-based aromatic dibasic acid synthesized by using the widely-sourced eugenol as a raw material is green and environment-friendly, can be used for synthesizing a bio-based polyamide, and has excellent mechanical properties and good dissolving and processing capacity, and the bio-based polyamide has high economy. The whole preparation process is simple in operation and easy to popularize.

The invention belongs to the technical field of medicines, and particularly relates to application of hibiscus (the hibiscus is a plant hibiscus flower and an extract and an active monomer thereof) in preparation of medicines for treating stomach diseases (atrophic gastritis, gastric mucosal lesion and gastric cancer). The invention discloses application of hibiscus syriacus in treatment of gastric diseases. The application comprises at least one of chronic atrophic gastritis treatment, gastric mucosa protection and gastric cancer prevention. In-vitro experiments show that the shrub althea flower extract, shrub althea flower polyphenol, syringic acid (I), protocatechuic acid (II), kaempferol (III) and kaempferol-7-O-beta-D-glucoside (IV) have obvious antioxidant activity and gastric mucosa protection activity, can obviously reduce the ROS content in ethanol-induced GES-1 cells and the expression of apoptosis marker protein Caspase-3 / Bax, and have a wide application prospect.

The application provides a construction method of UPLC characteristic spectrum of Qinglongyi medicinal material, standard decoction and formula granules, comprising the following steps: dissolving and extracting raw materials of the test sample by using a solvent to obtain a test solution; determining the test solution by using high performance liquid chromatography to obtain the UPLC characteristic spectrum of Qinglongyi medicinal material, standard decoction and formula granules; and the high performance liquid chromatography conditions are as follows: a C 18 column is used as the chromatographic column; acetonitrile solution is used as mobile phase A, and 0.1% formic acid aqueous solution is used as mobile phase B, and gradient elution is adopted. The application adopts the high performance liquid chromatography, selects acetonitrile-0.1% formic acid solution as the mobile phase for gradient elution, takes protocatechuic acid, vanillic acid, syringic acid, ellagic acid, rutin and quercitrin as the reference substances, establishes the UPLC characteristic spectrum method of Qinglongyi medicinal material, standard decoction and formula granules, and provides more scientific technical means for controlling the medicinal quality of Qinglongyi medicinal material, standard decoction and formula granules.

The invention discloses a method for rapidly determining various phenolic acid substances in a fermentation product, and belongs to the technical field of detection. The determination method comprises the following steps: 1. Taking a to-be-detected substance, and extracting phenolic acid substances in the to-be-detected substance through an alcohol precipitation-SAX solid-phase extraction combined technology to obtain a to-be-detected sample; analyzing the to-be-detected sample by adopting ultra-high performance liquid chromatography tandem triple quadrupole mass spectrometry to obtain the content of the target substance in the to-be-detected substance; the target substance is a non-volatile phenolic acid substance. Accurate quantification of trace and trace caffeic acid, dihydrocaffeic acid, ferulic acid, chlorogenic acid, gallic acid, vanillic acid, syringic acid, p-coumaric acid, salicylic acid and (+ / -)-catechin in fermentation products within 8-15 min is achieved by combining impurity removal and concentration pretreatment with ultra-high performance liquid chromatography tandem triple quadrupole mass spectrometry. According to the method, the pretreatment mode is convenient to operate, the detection process is fast, and the detection result is accurate.

The invention provides an electrochemical method for pairwise synthesizing syringic acid and adiponitrile. The method comprises the following steps: 1) mixing syringaldehyde, an alkaline electrolyte, an alcohol solvent, an alkyl glycoside surfactant and water, and adding the mixture into an anode chamber of an electrolytic cell; (2) acrylonitrile, phosphate, borate, a quaternary ammonium base surfactant and water are mixed and added into a cathode chamber of the electrolytic cell; and 3) heating the electrolyte in the cathode chamber and the anode chamber of the electrolytic cell, then carrying out an electrolytic reaction, carrying out electrochemical oxidation on syringaldehyde at the anode to synthesize syringic acid, enabling hydrated hydrogen ions to enter the cathode chamber across a membrane, and synthesizing adiponitrile with acrylonitrile at the cathode. The syringic acid synthesis method is clean, environmentally friendly and low in cost, meanwhile, the problem of anode corrosion in the operation process of electrosynthesis of adiponitrile is solved, and the tail gas safety risk caused by oxygen evolution of an anode for synthesis of adiponitrile is eliminated. The method has the advantages of simple steps, high total product yield, low equipment investment, low operation risk, mild reaction conditions, less three wastes and low energy consumption, and is suitable for wide industrial application.

The invention discloses a preparation method and application of a plant extract fermentation product for promoting anti-aging of cats, and belongs to the technical field of animal health care product preparation. Comprising a metabolite (LA20FM) of a brown algae extract which has an anti-aging function and is fermented by bifidobacterium adolescentis LifeAge20 and other raw materials, including one or more of D-sphingosine, luteolin, epigallocatechin, syringic acid, leucine, fucosterol, resveratrol, nicotinamide and glutathione. The metabolite of the brown algae extract fermented by the bifidobacterium adolescentis LifeAge20 disclosed by the invention has a remarkable effect in the anti-aging aspect, and can improve the content of nicotinamide adenine dinucleotide in vascular endothelial cells of cats, the angiogenesis capability and the antioxidant capability; the activity of beta-galactosidase in cells and the content of senescence phenotype markers are reduced, and a multi-channel anti-aging effect is realized. The LA20FM and additives are added to prepare the health-care agent, so that the health-care agent is more beneficial to anti-aging of pets and has a wide application prospect.

The invention relates to the technical field of baijiu, in particular to grain-flavored seasoning wine and a production method thereof, wet grains are collected and soaked in water, pretreatment is performed, and then water metering operation is performed by using the wet grains and the soaked in water. In order to improve the gelatinization degree and moisture of the fermented grains in the production of the white spirit, the operation of metering water in the retort after the wine is finished or before the wine is taken out of the retort and metering water after the wine is taken out of the retort is adopted, meanwhile, part of grain moistening water flows out of a grain pile after the grain moistening operation is finished, the grain moistening water contains rich anthocyanin and other grain aroma fermentation substrates, and the grain moistening water is used for metering water; grain moistening and water returning are achieved, generation of syringic acid and ferulic acid flavonoid compounds is promoted, finally, the syringic acid and ferulic acid flavonoid compounds are converted into polyphenol compounds and aromatic compounds, and a unique grain fragrance base of the Maotai liquor is formed.

A metal complex comprising: (a) a pharmaceutically acceptable central metal; (b) a DNA methyltransferase (DNMT) inhibitor; and (c) 2,5-dihydroxyterephthalic acid (DTA) and / or syringic acid (SA).

The application discloses a method for rapidly detecting 30 compounds in tea, such as catechins, flavonoids, anthocyanins, phenolic acids and amino acids, wherein the 30 compounds are gallic acid, theobromine, GC, protocatechuic acid, theophylline, EGC, theanine, chlorogenic acid, caffeine, catechin, syringic acid, caffeic acid, vanillic acid, epicatechin, EGCG, delphinidin, salicylic acid, GCG, p-coumaric acid, cyanidin, ferulic acid, sinapic acid, rutin, ECG, pelargonidin, myricetin, theaflavin, quercetin, apigenin and kaempferol. The application can realize simultaneous rapid qualitative and quantitative detection of the 30 compounds, and provides technical support for development of active substances in tea.

The invention discloses a Ganhai Weikang capsule specific chromatogram based on a multi-component material basis as well as a construction method and application thereof, and belongs to the technical field of quality control and evaluation of Chinese patent medicines. A high performance liquid chromatography-high resolution mass spectrometry method is adopted for detection, and glycyrrhizic acid, liquiritin, liquiritigenin, apiose liquiritin, naringenin, chlorogenic acid, syringic acid, protocatechuic acid, hesperidin, narirutin, p-coumaric acid and kaempferide are taken as reference substances; the specific chromatogram is successfully constructed by detecting different batches of Ganhai Weikang capsules. The method for detecting the specific chromatogram of the Ganhai Weikang capsule, established by the invention, is simple and convenient to operate, high in precision and rapid in analysis, can realize efficient and synchronous detection of 12 characteristic components, and has good stability, accuracy and reproducibility. According to the method, synchronous and rapid analysis of multiple components is realized, the detection efficiency is remarkably improved, and reliable scientific basis and technical support are provided for quality control and clinical curative effect guarantee of the Ganhai Weikang capsules.

The invention relates to the technical field of composite materials, in particular to a preparation method of a polyurethane nylon composite continuous fiber material, syringic acid is added as an antibacterial agent during preparation of antibacterial waterborne polyurethane, and the syringic acid has broad-spectrum antibacterial activity and can effectively inhibit growth of various bacteria and fungi, so that the antibacterial property of the polyurethane nylon composite continuous fiber material is improved; therefore, the composite fiber material is endowed with good antibacterial performance; nano silicon dioxide modified graphene oxide, modified nano calcium carbonate and modified talcum powder are added into the antibacterial waterborne polyurethane, and the nano additives can effectively enhance the mechanical properties of a polyurethane matrix, such as tensile strength, wear resistance and hardness, and improve the dispersity and stability of the material at the same time; the nano silicon dioxide modified graphene oxide provides excellent antibacterial performance, the modified nano calcium carbonate and the modified talcum powder are beneficial to improving the rigidity and the heat resistance of the material, and the mechanical performance of the composite fiber material can be improved after the antibacterial waterborne polyurethane and the nylon 6 are blended.

The present application belongs to the technical field of chemical component analysis and detection of traditional Chinese medicinal materials, and particularly relates to a method for simultaneously and quantitatively detecting six components in radix impatiens and application thereof. The method comprises the following steps: standard samples of six components, i.e. hydroxybenzoic acid, vanillic acid, syringic acid, 4-hydroxyacetophenone, 2,4-dihydroxyacetophenone and A-O-DCDT, are weighed respectively and prepared into a mixed control solution containing all the standard samples by using an organic solvent; an extracting agent is added to a test sample, and then the test sample is placed, ultrasonically extracted, cooled, fixed in volume, centrifuged, filtered, and dried to obtain a residue; the residue is redissolved and filtered to obtain a supernatant, which is the test sample solution; the mixed control solution and the test sample solution are detected by UPLC-DAD to obtain corresponding chromatograms; and the six components are qualitatively identified and quantitatively determined by comparing and analyzing the chromatograms of the mixed control solution and the test sample solution.

The invention relates to a rapid rooting culture medium for tissue culture seedlings and a preparation method thereof, and belongs to the technical field of tissue culture seedling culture mediums. The rapid rooting culture medium for the tissue culture seedlings mainly comprises the following components: an improved MS culture medium, 0.5 to 1.0 mg / L of 3-indolepropionic acid, 0.3 to 0.5 mg / L of naphthylacetic acid, 0.5 to 1.0 mg / L of sulfonated graphene, 1.0 to 2.0 mg / L of linalool, 1.0 to 2.0 mg / L of syringic acid, 1 to 2 mg / L of vitamin C, 3 to 4 mg / L of dipotassium glycyrrhizinate, 100 to 120 mg / L of highland barley oligopeptide, 30 g / L of sucrose and 7 g / L of agar. The culture medium provided by the invention can obviously improve the rooting rate of tissue culture seedlings, promote root development and improve the survival rate of rooted seedlings after transplanting.

The invention discloses a preparation method and application of a plant extract fermentation product for promoting aging resistance of dogs, and belongs to the technical field of animal health care product preparation. Comprising a metabolite (LA20k9) of a brown algae extract which has an anti-aging function and is fermented by bifidobacterium adolescentis LifeAge20-k9 and other raw materials, and the metabolite is prepared from one or more of avenine, fucosterol, 3 ', 4', 5, 7-tetrahydroxyflavone, ciprofibrate, nicotinamide, epigallocatechin, leucine, syringic acid and glutathione. The metabolite of the brown algae extract fermented by the bifidobacterium adolescentis LifeAge20-k9 disclosed by the invention has a remarkable effect in the anti-aging aspect, and can improve the content of nicotinamide adenine dinucleotide in vascular endothelial cells of dogs, the angiogenesis capability and the antioxidant capability; the activity of beta-galactosidase in cells and the content of senescence phenotype markers are reduced, and a multi-channel anti-aging effect is realized. LA20k9 and additives are added to prepare the health-care agent, so that the health-care agent is more beneficial to aging resistance of pets and has a wide application prospect.