259results about "Oximes preparation" patented technology

The invention discloses a Schiff base tyramine curing agent and application thereof in preparation of epoxy resin with intrinsic flame-retardant and shape memory functions, and belongs to the field of flame-retardant curing agents. The structure of the Schiff base tyramine curing agent provided by the invention contains a Schiff base structure, and the Schiff base structure in an epoxy cross-linked network can promote the epoxy resin to be degraded into carbon in advance, so that the fire safety of the epoxy resin is greatly improved. Meanwhile, the Schiff base structure has dynamic reversibility, and the epoxy resin prepared based on the Schiff base tyramine curing agent has degradable characteristics and dynamic characteristics. The epoxy resin prepared on the basis of the Schiff base tyramine curing agent can be controllably degraded under specific conditions while good solvent resistance is maintained. In addition, the epoxy resin prepared on the basis of the Schiff base tyramine curing agent shows good shape memory performance, and the shape recovery rate of the epoxy resin is 97% or above.

Described herein are novel methods of synthesizing 2-amino-5-chloro-N,3-dimethylbenzamide. Compounds prepared by the methods disclosed herein are useful for preparation of certain anthranilamide compounds that are of interest as insecticides, such as, for example, the insecticides chlorantraniliprole and cyantraniliprole.

The invention relates to a method for synthesizing trifloxystrobin through a one-pot method, and belongs to the technical field of organic synthesis.The method comprises the following steps that 1, E-2-(2-halomethylphenyl)-2-methoxyiminoacetic acid methyl ester, m-trifluoromethyl acetophenone, hydroxylamine hydrochloride or hydroxylamine sulfate and a solvent are added into a reaction flask, then alkali is added, and after addition is completed, a heat preservation reaction is conducted; and Step 2, after the reaction is finished, filtering to remove salt, and concentrating filtrate under reduced pressure to obtain trifloxystrobin. Compared with a traditional synthesis method of the trifloxystrobin, the synthesis method of the trifloxystrobin has the advantages that the 3-trifluoromethyl acetophenone and the E-2-(2-halomethylphenyl)-2-methoxyiminoacetic acid methyl ester are used as raw materials, the trifloxystrobin is directly synthesized by a one-pot method, the reaction route is short, the raw material cost is low, and the synthesis method of the trifloxystrobin by the one-pot method has the advantages that the synthesis efficiency is high, and the synthesis cost is low. The preparation method has the advantages that the preparation of m-trifluoromethyl acetophenone oxime from m-trifluoromethyl acetophenone is not needed, the whole synthesis process is simpler and more efficient, the reaction conditions are mild, and the preparation method is suitable for industrial large-scale production.

The present invention relates to the technical field of cyclohexanone catalytic oxidation, and specifically to a titanium silicalite molecular sieve and a preparation method thereof, a method for preparing cyclohexanone oxime, and a method for preparing caprolactone. The method comprises: (1) uniformly mixing a silicon source, an alkaline template, a titanium source, and water to obtain a titanium silicalite sol; and (2) adding a silanization agent to the titanium silicalite sol, and hydrothermally crystallizing and calcining the obtained mixture. The present invention treats the titanium silicalite sol precursor with a specific silanization agent to prepare a titanium silicalite molecular sieve. When used in the catalytic oxidation of cyclohexanone and the ammoximation reaction of cyclohexanone, the titanium silicalite molecular sieve has high catalytic activity, and the conversion rate of cyclohexanone can be increased to above 91%.

The invention discloses a copper-based catalyst for catalyzing partial hydrogenation of nitrocyclohexane to prepare cyclohexanone-oxime as well as a preparation method and application of the copper-based catalyst. The catalyst comprises a main active component and an auxiliary active component, the main active component is copper, the auxiliary active component is selected from one or more of titanium, vanadium, chromium, molybdenum, zirconium, cadmium, indium, tin, antimony, niobium, silver, iron, zinc, magnesium, aluminum, bismuth, manganese, lanthanum, gold or lead, the total molar ratio of the copper to the auxiliary active component is (100-1): 1, and the catalyst is prepared by adopting a coprecipitation method or a supported impregnation-coprecipitation method. And the process is simple and green. Under mild conditions, the catalyst can realize the conversion rate gt of nitrocyclohexane; the selectivity of cyclohexanone-oxime is greater than or equal to 99%, and the method is obviously superior to the existing non-noble metal system, and is low in cost, good in stability and suitable for industrial production of green synthesis of caprolactam.

The invention provides a method for preparing a Ti-MOR catalyst through one-pot aftertreatment and application of the Ti-MOR catalyst, and relates to the field of molecular sieve catalyst material preparation.The method comprises the following steps that acid liquor, a titanium source and deionized water are mixed, and a co-treating agent is obtained; adding a fresh MOR molecular sieve into the co-treatment agent in a stirring state, uniformly mixing, and pretreating to obtain pretreated mixed gel; putting the pretreated mixed gel into a reaction kettle, heating, and carrying out heat preservation for post-treatment; and after heat preservation is finished, cooling, washing with water, drying and roasting to obtain the Ti-MOR catalyst. According to the method, an acid and titanium source co-treating agent one-step liquid-phase titanium loading process is adopted to replace a traditional two-step method, efficient titanium loading of the MOR molecular sieve is achieved through the acid synergistic effect, and the catalytic conversion rate and selectivity are both improved to 95% or above; and the co-treatment agent can be recycled for three times, so that the utilization rate of the acid liquor is increased, the emission of waste acid is reduced by 30% or above, and an innovative solution is provided for industrial production of the Ti-MOR which is simplified in process, controlled in cost and environmentally friendly.

The present invention relates to the preparation of cyantraniliprole, comprising the preparation of 8-methyl-2,4-dioxo-1,4-dihydro-2H-benzo[d][1,3]oxazine-6-carbonitrile key intermediate via 2-amino-5-((hydroxyimino)methyl)-3-methylbenzoic acid. Wherein hydroxylamine attacks a benzylic formyl group, to obtain the 2-amino-5-((hydroxyimino)methyl)-3-methylbenzoic acid, that undergoes simultaneously or by consecutive steps dehydrogenation and cyclization to obtain the benzo[d][1,3]oxazine group and the cyano group of the desired product. In addition, an improved method for the synthesis of the benzylic formyl group is also displayed.

The invention discloses a column [n] arene benzoquinone oxime ortho-position functionalized derivative and a preparation method thereof, and particularly relates to a preparation method for obtaining the column [n] arene benzoquinone oxime ortho-position functionalized derivative by reacting column [n] arene [1] benzoquinone oxime with a Grignard reagent. In the structure of column [n] arene [1] benzoquinone oxime, when alpha, beta-unsaturated ketone and a Grignard reagent are subjected to nucleophilic addition reaction, a 1, 4-addition product with high yield can be obtained, and no 1, 2-addition product exists. The method is mainly characterized in that protons can be removed from hydroxyl of oxime in column [n] arene [1] benzoquinone oxime under an alkaline condition, and oxygen negative ions of the hydroxyl are combined with positively charged metal magnesium atoms in a Grignard reagent to form a six-membered ring transition state, so that R negative ions can attack a No.4 carbon atom of alpha, beta-unsaturated ketone, and a 1, 4-addition reaction is carried out. The preparation method disclosed by the invention is mild in condition and can be carried out without harsh reaction conditions.

The invention discloses a preparation method and application of a titanium silicalite molecular sieve TS-2, and belongs to the technical field of molecular sieves. The preparation method specifically comprises the following steps: (1) adding quaternary ammonium base and quaternary ammonium salt into water, and mixing and stirring; (2) adding a silicon source, mixing and stirring; (3) adding an isopropanol solution of a titanium source, and stirring for hydrolysis; (4) heating and stirring, and heating and crystallizing; and (5) cooling, filtering, washing, drying and roasting. The preparation method comprises the following steps: regulating the pH value to be lower than 12 through a composite template agent (quaternary ammonium base and quaternary ammonium salt), enabling the concentration of tetrabutylammonium cations of a system to be in a relatively high state, and preparing a titanium silicalite molecular sieve TS-2, 3-dibromo-2, 3-dibromo-2, 3-dibromo-2, 3-dibromo-2, 3-dibromo-2, 3-dibromo-2, 3-dibromo-2, 3-dibromo-2, 3-dibromo-2, 3-dibromo-2, 3-dibromo-2, 3-dibromo-2, 3-dibromo-2, 3-dibromo-2, 3- The catalyst has high mass transfer efficiency and high catalytic performance.

The invention discloses a hierarchical porous Ti-MOR molecular sieve as well as a preparation method and application thereof, and belongs to the technical field of molecular sieves. The preparation method comprises the following steps: at room temperature, mixing a silicon source, an aluminum source, an alkali source, a seed crystal, a pore-enlarging agent and water to obtain a gel precursor for synthesizing the molecular sieve, carrying out hydrothermal crystallization and alkali treatment to obtain a hierarchical pore structure MOR molecular sieve with mesopores and macropores, carrying out acid pickling, and carrying out gas-solid phase same crystal substitution on the molecular sieve and titanium tetrachloride to finally prepare the hierarchical pore Ti-MOR molecular sieve. According to the hierarchical porous Ti-MOR molecular sieve disclosed by the invention, reactant molecules with relatively large dynamic diameters can effectively enter and exit zeolite pore channels, and the hierarchical porous Ti-MOR molecular sieve shows excellent catalytic performance in a cyclohexanone oximation reaction.

The invention relates to a method for preparing ketoxime compounds, which comprises the following steps: contacting a ketone compound, a catalyst and an ammonia source in a liquid-phase medium to obtain a reaction mixture, and releasing ammonia gas from the ammonia source; the catalyst comprises a carrier and active metal loaded on the carrier, the active metal comprises IB group metal and VIII group metal, and the carrier comprises a titanium silicalite molecular sieve; introducing the first raw material gas and the second raw material gas into the reaction mixture to be in contact with a catalyst for in-situ reaction to obtain a reaction product containing the ketoxime compound; wherein the first feed gas comprises hydrogen, and the second feed gas comprises oxygen. According to the method, hydrogen and oxygen are used as reaction raw material gases, ketoxime is prepared through in-situ ammoximation of ketone compounds, the safety problem caused by production, use, storage and transportation of hydrogen peroxide is solved, and the method is simple in process and environmentally friendly.

The application provides a synthesis method of p-benzoquinone dioxime. The synthesis method comprises the following steps: (1) adding solid acid into an ethanol solution of phenol to obtain a mixed solution A, then vacuumizing and filling with inert gas; dissolving nitrite into ethanol, uniformly mixing to obtain an ethanol solution of nitrite, then vacuumizing and filling with inert gas; in an inert gas atmosphere, adding the ethanol solution of nitrite into the mixed solution A dropwise to perform nitrosation reaction, to obtain a reaction liquid B; in the inert gas atmosphere, adding an ethanol solution of hydroxylamine into the obtained reaction liquid B to perform oximation reaction; after the reaction is completed, filtering the obtained reaction liquid C, performing reduced pressure distillation on the obtained filtrate, and performing washing, filtering and drying on the obtained residual liquid of the reduced pressure distillation, to obtain p-benzoquinone dioxime. The method provided by the application reduces the occurrence of side reactions, improves the conversion rate of the reaction, and improves the yield and purity of p-benzoquinone dioxime.

The invention discloses a synthesis method of 9-dichloromethylene-5-amino-benzonorbornene and an intermediate product, the synthesis method comprises the following steps: firstly, synthesizing a cyclization compound 1 as shown in a formula 1 from a cold solution of 6, 6-dichlorofulvene and 1, 4-benzoquinone under the action of a solution of a catalyst I, carrying out oximation reaction on the cyclization compound 1 prepared in the step a and hydroxylamine salt under an alkaline condition, and carrying out post-treatment to obtain the 9-dichloromethylene-5-amino-benzonorbornene. Under the action of a catalyst II, adding the oximate 2 prepared in the step b into a closed container, carrying out hydrogenation reduction to obtain 9-dichloromethylene-5-amino-benzo norbornene, and directly treating the reduction product with acid to obtain 9-dichloromethylene-5-amino-benzo norbornene, namely the 9-dichloromethylene-5-amino-benzo norbornene, namely the 9-dichloromethylene-5-amino-benzo norbornene. According to the method, the cyclization compound is oximated firstly, then the residual carbonyl and two double bonds on the ring are subjected to one-step reduction through catalytic hydrogenation, the working procedure is optimized, meanwhile, reduction by using expensive sodium borohydride is avoided, the method is short in synthesis route and suitable for industrialization, and the production cost is reduced.

The invention belongs to the technical field of preparation of herbicides, and particularly relates to a preparation method of tralkoxydim. The preparation method comprises the following steps: carrying out ethylation reaction on 3-hydroxy-5-(2, 4, 6-trimethylphenyl)-2-propoximido-cyclohex-2-ene-1-ketone and halogenated ethane under an alkaline condition, so as to prepare tralkoxydim. According to the method, the use of ethoxyamine hydrochloride or ethoxyamine in the traditional process is innovatively avoided, the raw material cost is reduced, the ethylation reaction is carried out by using halogenated ethane, the reaction raw materials are cheap and easy to obtain, meanwhile, single sodium / potassium halide wastewater is produced, the wastewater treatment process is greatly simplified, meanwhile, the generation of carnallite wastewater and carnallite-containing solid waste is eliminated, and the method is suitable for industrial production. The method has the advantages of environmental protection, economy and simple process, and is suitable for industrial large-scale production.

This invention provides a method for preparing dibenzoyl-p-benzoquinone dioxime using a microchannel reactor. The method includes the following steps: 1,3-dicyclohexylcarbodiimide and a catalyst are mixed uniformly and preheated to obtain a premix; a chloroform solution of p-benzoquinone dioxime, a chloroform solution of benzoic acid, and the premix are simultaneously introduced into the microchannel reactor for reaction; the resulting reaction solution is subjected to vacuum distillation, washing, filtration, and drying to obtain dibenzoyl-p-benzoquinone dioxime. The synthesis method of this invention features high reaction conversion rate, high production efficiency, few side reactions, and high safety. The obtained dibenzoyl-p-benzoquinone dioxime product has stable quality. Furthermore, the organic solvent used can be recovered and reused after vacuum distillation, overcoming the problems of inaccurate temperature control, poor safety, numerous side reactions, and difficult waste treatment in traditional processes. This provides a new approach for the synthesis of dibenzoyl-p-benzoquinone dioxime.

The embodiment of the present application provides a kind of spherical dihydroxy glyoxime and its preparation method and energetic material.The method comprises the following steps: hydrochloric acid solution and dihydroxy glyoxime metal salt suspension are simultaneously added into reaction bottom liquid containing regulator, crystallization reaction is carried out, and crystal suspension is obtained;The crystal suspension is filtered, and the spherical dihydroxy glyoxime is obtained.The method is used to achieve the effect of providing the flowability and bulk density of spherical dihydroxy glyoxime.

The invention relates to a method for preparing anhydrous acetaldoxime by a system for co-producing diacetylmonoxime and acetaldoxime, and relates to the technical field of acetaldoxime. The method comprises the following steps: adding diacetylmonoxime, acetaldehyde and a modified TS-1 molecular sieve into a reactor, and reacting to generate crude acetaldehyde oxime; feeding the crude acetaldehyde oxime into an acetaldehyde removal tower for rectification separation; rectifying and separating acetaldehyde tower bottoms to obtain butanone; adding an extracting agent into the tower top acetaldoxime solution, and feeding into a distillation kettle for extraction; the extracted acetaldehyde oxime is fed into an acetaldehyde oxime finished product tower to be further rectified and purified; the preparation method comprises the following steps: reacting a TS-1 molecular sieve, anhydrous toluene and 3-mercaptopropyltrimethoxysilane to obtain a sulfhydrylated TS-1 molecular sieve; the preparation method comprises the following steps: taking a sulfhydrylated TS-1 molecular sieve, tetrahydrofuran, diethyl vinylphosphonate, mercaptododeborane disodium salt and Darocur1173 as photoinitiators, and reacting under the irradiation of 365nm ultraviolet light to obtain the modified TS-1 molecular sieve. The acetaldehyde oxime prepared by the method has higher content and yield.

The present invention provides a synthesis method and application of high-value nitrogen-containing compounds by photocatalytic reduction of nitrogen-containing small molecules. The synthesis method comprises the following steps: mixing a photocatalyst, a nitrogen-containing small molecule, and an electron donor, adding or not adding a co-catalyst, preparing a reaction solution, introducing an inert gas into the reaction solution and sealing it, and irradiating the reaction solution with visible light to obtain the high-value nitrogen-containing compound; wherein the nitrogen-containing small molecule comprises one or more of N2, NO, N2O, nitrate, and nitrite; and the photocatalyst comprises one or more of CdS, CdSe, ZnSe, CuInS2, CdSe / ZnS, CdSe / CdS, ZnSe / CdS, CdSe / ZnSe, CdS / ZnS, CdSe / CdS / ZnS, CdS / TiO2, and CdSe / TiO2. This synthesis method can utilize nitrogen-containing small molecules for efficient reduction to obtain high-value nitrogen-containing compounds such as NH3, urea or cyclohexanone oxime, and has high synthetic application value. At the same time, this synthesis method has mild reaction conditions, high visible light utilization rate, cheap and easily available raw materials, and strong applicability.

A method for preparing the insecticide N-(1-methylcyclopropyl)-2-(3-pyridinyl)-2H-indazole 4-carboxamide is disclosed. A method for preparing the intermediate N-(1-methylcyclopropyl)-2-(3-pyridinyl)-2H-indazole 4-carboxamide is also disclosed.

The invention provides an aldehyde insect pheromone derivative, which takes a compound containing at least one primary amine group as a carrier, and aldehyde insect pheromone forms an imine derivative with the compound through chemical reaction. The invention also provides a preparation method, application and a release method of the aldehyde insect pheromone derivative. According to the aldehyde insect pheromone derivative provided by the invention, aldehyde insect pheromones are treated in a chemical reaction manner, the stability of the aldehyde insect pheromones can be remarkably improved, slow release and controlled release of the pheromones can also be realized, the carrier material is wide in source, more in selectivity, convenient and economical, and in addition, the aldehyde insect pheromone derivative has good application prospects. The aldehyde insect pheromone derivative provided by the invention can also realize combined fixation and release of various pheromones, so that trapping, prevention and control of various insects can be realized.

The present invention relates to a method for preparing a mixture containing cyclohexanol and cyclohexanone, comprising the step of hydrogenating cyclohexyl hydroperoxide in cyclohexane in the presence of a Raney nickel catalyst to obtain cyclohexanol and cyclohexanone.

The present invention relates to the preparation and application of difluoroalkene oxime ether derivatives. The general structural formula of the difluoroalkene oxime ether derivatives is shown in formula (I):. It has been found through research that the difluoroalkene oxime ether derivatives disclosed in the present invention have good biological activities against common and severely harmful agricultural pests / mites such as Plutella xylostella, Ostrinia furnacalis, Spodoptera frugiperda, and Tetranychus cinnabarinus. Therefore, they can be used as insecticidal / acaricidal candidate substances for the development of new, highly efficient, low-toxic, and environmentally friendly insecticides.

The invention provides an aryl alkyl ketoxime derivative as well as a preparation method and application thereof, and relates to the field of aryl oxime derivatives. The preparation method of the aryl alkyl ketoxime derivative comprises the following steps: by taking potassium formate as an additive, carrying out free radical reaction on a compound I and a compound II under ultraviolet irradiation in the presence of tert-butyl nitrite to obtain the aryl alkyl ketoxime derivative, the compound I is substituted iodobenzene or iodopyridine; the compound II is substituted styrene or thienyl ethylene; wherein a hydrogen atom transfer / single electron transfer relay sequence is utilized to activate a compound I, and tert-butyl nitrite is adopted as a bifunctional reagent, and is used as a hydrogen atom transfer reagent and an oxime source. According to the preparation method of the aryl alkyl ketoxime derivative, pre-functionalization is not needed, a reaction substrate is wide in universality and good in compatibility, reaction conditions are mild, operation is easy and convenient, a target product can be efficiently and rapidly prepared on the premise of high yield, and a new way is provided for oxime synthesis.

The invention belongs to the technical field of pesticides, and particularly relates to carvone oxime ether compounds as well as a preparation method and application thereof. The carvone oxime ether compound has a chemical structure as shown in a formula (I). The invention provides a series of brand new carvone oxime ether compounds for the first time. In addition, the invention also provides a synthetic method of the carvone oxime ether compound, the product prepared by the synthetic method is high in yield and easy to separate, and the synthetic method is an optimal synthetic route for preparing the carvone oxime ether compound; the carvone oxime ether compound can be used for controlling stored grain pests, especially controlling tribolium castaneum of wheat, rice, corn, sorghum, peanuts, oilseed rape, soybeans and the like, and has the characteristics of high acting speed and high activity. The carvone oxime ether compound disclosed by the invention can be used as a stored grain pest control fumigant, has good development potential, and provides a new thought for developing and creating a new green fumigant.

The present invention belongs to the technical field of pathogen control, and particularly relates to a cinnamic acid oxime ester compound, a preparation method and an application thereof. The cinnamic acid oxime ester compound has a structural formula as shown in Formula I: The preparation method of the compound of the present invention is simple in operation and easy to obtain raw materials. The compound has broad-spectrum bactericidal activity, and particularly has obvious inhibitory effects on Botrytis cinerea of tomato, Valsa mali of apple tree and Gaeumannomyces graminis of wheat, and can be used as a bactericide for the prevention and control of the above plant diseases.

The utility model relates to the field of production devices of organic chemical raw materials, and discloses a cyclohexanone oxime preparation device. The device comprises a reaction unit, a washing unit 6, a product separation unit 7 and an extraction unit 8, wherein the reaction unit comprises at least one reactor 1, a reaction cooler 2, a catalyst separator 3 and a membrane filter 4 which is arranged in the catalyst separator 3 or is communicated with a water phase outlet of the catalyst separator 3; the reactor 1 is provided with a raw material inlet communicated with a circulating catalyst slurry pipeline 10 and a hydrogen peroxide inlet communicated with a hydrogen peroxide supply device, and the circulating catalyst slurry pipeline 10 is provided with a cyclohexanone inlet and an ammonia inlet. The device disclosed by the utility model obviously prolongs the service life of the catalyst, effectively removes impurities in cyclohexanone oxime, and has higher cyclohexanone conversion rate and cyclohexanone oxime selectivity.

The present invention provides a method for preparing trifloxystrobin. The method for preparing trifloxystrobin comprises the following steps: using trifloxystrobin characteristic impurities or crude trifloxystrobin containing trifloxystrobin characteristic impurities as raw materials, reacting in the presence of methanol and a base to obtain trifloxystrobin. The preparation method of the present invention uses trifloxystrobin characteristic impurities as starting materials and obtains the target product through a one-step reaction. The conditions of the preparation method are mild and the process is simple. Trifloxystrobin with high yield and high purity can be obtained, which can not only improve the quality of trifloxystrobin but also increase the yield of trifloxystrobin.

The application discloses a preparation method of a non-conjugated functionalized olefin compound, and the method is carried out in a cobalt / photocatalysis dual catalytic system which is composed of a cobalt catalyst, a ligand, a photocatalyst, a hydrogen source, a base and a solvent. β The target product is efficiently and selectively synthesized through reaction of an ethylenic compound or a halogenated compound or an electron-deficient olefin represented by formula (2) with acetylene as a C2 synthetic unit. The application adopts a cobalt / photocatalysis dual catalytic synergistic mechanism, has mild conditions (normal temperature and pressure, visible light driving), uses water as a green hydrogen source, uses acetylene as a cheap C2 source, has high atom economy, has good substrate universality, and the compound represented by formula (1) is easy to be prepared through Friedel-Crafts acylation or is commercially available, and the compound represented by formula (1) is easy to generate the compound (III) represented by formula (2) under the action of a base. The obtained non-conjugated olefin is a key intermediate for synthesizing high-value-added fine chemicals such as fragrances and insect pheromones, and has wide application prospects.

The invention discloses a method for co-production of 2, 4-dichloro-5-fluoroacetophenone and hydroxylamine hydrochloride, and belongs to the technical field of organic chemical industry, 2, 4-dichlorofluorobenzene is used as a raw material, alkylation and reaction with tert-butyl nitrite are performed to generate oxime, and then hydrochloric acid hydrolysis is performed to generate 2, 4-dichloro-5-fluoroacetophenone and hydroxylamine hydrochloride; according to the method, co-production of the 2, 4-dichloro-5-fluoroacetophenone and the hydroxylamine hydrochloride is innovatively realized, not only are high yield and high purity of the target product 2, 4-dichloro-5-fluoroacetophenone ensured, but also the nitrogen element in the reaction is recycled and converted into the hydroxylamine hydrochloride with high additional value, and the atom economy is remarkably improved; according to the method, the operation process is greatly simplified, the use of dangerous reagents is avoided, and the intrinsic safety and environmental friendliness of the process are improved from the source; the method is simple to operate, safe and environment-friendly, the production cost is effectively reduced, and the market competitiveness of the product is enhanced.

The invention relates to a preparation method of a trifloxystrobin intermediate (E)-2-(2-bromomethyl phenyl)-2-methoxyimino methyl acetate, and belongs to the technical field of organic chemistry. The method comprises the following steps: by taking a trifloxystrobin intermediate (E)-2-(2-bromomethyl phenyl)-2-methoxyimino methyl acetate containing dibromo impurities as a raw material and an organic solvent I as a reaction medium, carrying out debromination reaction at 5-60 DEG C by using phosphite, desolventizing and extracting a reaction solution, and crystallizing to obtain the high-purity (E)-2-(2-bromomethyl phenyl)-2-methoxyimino methyl acetate. According to the method disclosed by the invention, the dibromo impurity of the trifloxystrobin intermediate is subjected to debromination treatment by adopting the phosphite, so that the dibromo impurity is converted into the trifloxystrobin intermediate. By adopting the method provided by the invention, the conversion time of the dibromo impurity can be obviously shortened, the content and the yield of the trifloxystrobin intermediate obtained by conversion are both higher than 95%, and the reaction efficiency and the quality of the intermediate are greatly improved.