45results about "Quinone preparation" patented technology

This invention belongs to the field of veterinary drug technology, specifically relating to a 2,3-disubstituted naphthoquinone compound, its uses, and a preparation method. The 2,3-disubstituted naphthoquinone compound has the general formula: where X is selected from C, NH, O, and S; where X is selected from C, the X-R1 substituent represents an aryl substituent; when X is selected from NH, R1 is selected from hydrogen atom, C1-6 alkyl, C3-6 cycloalkyl, substituted aryl, substituted benzyl, or substituted acyl; when X is selected from O, R1 is selected from hydrogen atom, C1-6 alkyl, C3-6 cycloalkyl, C4-6 cycloalkyl, C5-6 cycloalkyl, C6-6 cyclo ... 3-6 cycloalkyl, substituted benzyl, substituted acyl; when X is selected from S, R1 is selected from C1-6 alkyl, substituted aryl, substituted benzyl; R2 is selected from C1-16 alkyl, substituted aryl, Ra-(CH2)n-, Ra-CO-(CH2)n-; This series of compounds has novel structures, excellent antiparasitic activity, and has been successfully applied in the field of veterinary drugs, solving long-standing safety and toxicity problems; its synthesis process is simple, the conditions are mild, and it can efficiently prepare a variety of 2,3-disubstituted naphthoquinone compounds.

The invention discloses a synthesis method of 9-dichloromethylene-5-amino-benzonorbornene and an intermediate product, the synthesis method comprises the following steps: firstly, synthesizing a cyclization compound 1 as shown in a formula 1 from a cold solution of 6, 6-dichlorofulvene and 1, 4-benzoquinone under the action of a solution of a catalyst I, carrying out oximation reaction on the cyclization compound 1 prepared in the step a and hydroxylamine salt under an alkaline condition, and carrying out post-treatment to obtain the 9-dichloromethylene-5-amino-benzonorbornene. Under the action of a catalyst II, adding the oximate 2 prepared in the step b into a closed container, carrying out hydrogenation reduction to obtain 9-dichloromethylene-5-amino-benzo norbornene, and directly treating the reduction product with acid to obtain 9-dichloromethylene-5-amino-benzo norbornene, namely the 9-dichloromethylene-5-amino-benzo norbornene, namely the 9-dichloromethylene-5-amino-benzo norbornene. According to the method, the cyclization compound is oximated firstly, then the residual carbonyl and two double bonds on the ring are subjected to one-step reduction through catalytic hydrogenation, the working procedure is optimized, meanwhile, reduction by using expensive sodium borohydride is avoided, the method is short in synthesis route and suitable for industrialization, and the production cost is reduced.

The invention discloses a non-planar pi-conjugated naphthoquinone derivative with an asymmetric structure, a preparation method of the non-planar pi-conjugated naphthoquinone derivative and application of the non-planar pi-conjugated naphthoquinone derivative in an aqueous flow battery, and relates to the technical field of electrochemical energy storage. Methyl 4-aminobenzoate is added into hydrochloric acid, then the mixture and sodium nitrite are dissolved in water to be mixed to obtain a diazonium salt solution, and 2-hydroxy-1, 2, 4-triazole is added into the diazonium salt solution to be mixed to obtain a diazonium salt solution; 2, 4-naphthoquinone is dissolved in a KOH solution and mixed with a diazonium salt solution, after hydrochloric acid acidification, acetic acid recrystallization purification is conducted, and BANQ is obtained; the capacity fading rate of the modified naphthoquinone derivative BANQ is as low as 0.00018% per circle, the modified naphthoquinone derivative BANQ shows excellent cycling stability and redox reversibility, the BANQ molecule has an asymmetric non-planar pi conjugation characteristic, and the sensitivity of a redox core to nucleophilic / electrophilic attack is greatly reduced, so that the cycling stability is improved, and the service life is prolonged. And a new direction and possibility are provided for constructing green sustainable large-scale organic redox active molecules for energy storage through artificial modification of natural products.

The present invention relates to the synthetic functionalization of an anthraquinone molecule substituted with at least one hydroxyl or amino group. In some aspects of the invention, a mixture containing the anthraquinone starting material, an aldehyde, a base, an optional solvent, and an optional catalyst is reacted with hydrogen, and then with an oxidizing agent. In other aspects of the invention, the synthetic functionalization of the anthraquinone molecule is carried out electrochemically, rather than chemically, using a divided electrolytic cell.

The application belongs to the field of medicine synthesis, and specifically provides a daunorubicin intermediate compound. The daunorubicin can be synthesized by pure chemical synthesis by using the intermediate compound. The daunorubicin is synthesized by taking 2,5-dihydroxybenzyl alcohol as a raw material. The route has low raw material cost, mild reaction condition, convenient post-treatment, high total yield, and good industrial application prospect.

The utility model discloses a kettle type and pipe type 2-alkylanthraquinone synthesis device for continuous ring-closure reaction, which is characterized in that BE acid and fuming sulfuric acid can be slowly dissolved and prepared and temporarily stored through a dissolving kettle at low temperature, so that unnecessary organic matters possibly derived in the dissolving step are reduced; steam with stable temperature circulates in an interlayer of the reaction tube, compared with containers such as tanks and cylinders, the reaction tube can quickly heat a dissolving solution in a smaller and more uniform heat exchange volume and a larger heat exchange area ratio, the dissolving solution can be quickly switched to a required reaction temperature and then is stabilized at the reaction temperature, and the product yield is increased by 10-15%; the closed-loop liquid obtained by the tubular reactor can be immediately cooled by the cooler, and the quickly cooled closed-loop liquid can be immediately collected.

This invention belongs to the technical field of 2-pentylanthraquinone production equipment, specifically a continuous closed-loop reaction device for preparing 2-pentylanthraquinone and its usage method. Addressing the problems of low preparation efficiency, long preparation time, high labor intensity for employees, and air pollution caused by released gases in existing technologies, the following solution is proposed: a workbench, with a gas conversion box rotatably connected to the top of the workbench, a rotating disk fixedly connected to the top of the gas conversion box, multiple connecting plates fixedly connected to the outer wall of the rotating disk, and gaskets fixedly connected to the top of the connecting plates. In this invention, the cooperation of a first magnet and a second magnet can drive the rotating shaft, a first slide rod, and a second slide rod to move up and down, thereby automatically completing stirring, depressurization, gas collection, and mixed liquid collection operations without manual operation, reducing the labor intensity of workers. Furthermore, multiple closed-loop reaction vessels react sequentially, improving the preparation efficiency of the mixed liquid.

The application belongs to the field of medicine synthesis, and particularly relates to a chemical synthesis method of an epirubicin intermediate, daunorubicin. The daunorubicin is synthesized by taking 2,5-dihydroxybenzyl alcohol as raw material, the route has low raw material cost, mild reaction condition, convenient post-treatment, high total yield, and has a good industrial application prospect.

The invention discloses a synthesis method of 1, 1-diarylethene, which comprises the following steps: by taking aryl fluorosulfonate and sulfonyl hydrazone as raw materials, in the presence of a palladium catalyst, a ligand, alkali and an organic solvent, heating to carry out coupling reaction, and after the reaction is finished, carrying out post-treatment to obtain a 1, 1-diarylethene compound. The method has the advantages that the aryl fluorosulfonate reagent is easy to prepare and store, the reaction selectivity is high, the functional group compatibility is good, the substrate application range is wide and the like, and the yield is as high as 91%. As the 1, 1-diarylethene compound is an important functional molecular skeleton structure, the 1, 1-diarylethene compound has very wide application in the fields of fine chemical engineering and pharmacy; therefore, the method has great application value and social and economic benefits.

The preparation method of the strontium-magnesium-based anthraquinone degradation product regeneration catalyst provided by the application is as follows: magnesium salt and a surfactant are dissolved in deionized water to prepare a magnesium salt solution, a silicate solution is added dropwise into the magnesium salt solution to obtain a slurry, then the slurry is subjected to hydrothermal reaction, and after the reaction is completed, the slurry is cooled to room temperature, the precipitate is washed and dried to obtain a magnesium silicate filter cake, and the magnesium silicate filter cake is dispersed in deionized water to obtain a magnesium silicate slurry; under stirring, a strontium salt solution and a silicate solution are simultaneously added dropwise into the magnesium silicate slurry, after the dropwise addition is completed, the obtained slurry is subjected to hydrothermal reaction, and after the reaction is completed, the obtained precipitate is washed and dried to obtain a catalyst precursor; the obtained catalyst precursor is placed in a muffle furnace for high-temperature calcination, and after the reaction is completed, the obtained catalyst precursor is cooled to room temperature, and the catalyst is obtained. The catalyst prepared by the method has strontium silicate / magnesium silicate double sites, the particle size of the active component of the catalyst is small, and the catalyst has high catalytic activity and selectivity for anthraquinone degradation product regeneration.

The invention relates to the technical field of synthesis, and provides a buparvaquone preparation method, which comprises: S1, carrying out a reaction on tetrahydrofuran, sodium hydride, p-tert-butyl cyclohexanone and triethyl phosphoryl acetate to prepare an intermediate 1; s2, carrying out hydrogenation reaction on the intermediate 1 under the action of a catalyst to obtain an intermediate 2; s3, carrying out hydrolysis reaction on the intermediate 2 to obtain an intermediate 3; and S4, carrying out C-C coupling reaction on the intermediate 3, and finally, carrying out heating reaction under the catalysis of potassium hydroxide to obtain buparvaquone. The intermediate 1 is 4-tert-butyl cyclohexane subunit ethyl acetate; the intermediate 2 is 4-tert-butyl cyclohexyl ethyl acetate; the intermediate 3 is 4-tert-butyl cyclohexyl acetic acid; the carrier of the catalyst is diatomite, and the active components are alloyed Pd and Fe. Through the technical scheme, the problem of low total yield of buparvaquone in the prior art is solved.

The application is suitable for the technical field of reaction devices, and provides a reaction device for synthesizing 2-pentylanthraquinone, which comprises a bottom plate, a support frame fixed on the bottom plate, and a reaction barrel fixed on the support frame, and further comprises a sealing cover, a first rotating disc, a guide sliding block, a stirring shaft, a motion track adjusting mechanism and a rotating assembly; a discharge pipe is communicatively arranged at the bottom of the reaction barrel. The motion track adjusting mechanism drives the first rotating disc to rotate, the first rotating disc drives the guide sliding block to revolve, the guide sliding block drives the stirring shaft to revolve, the stirring shaft drives the stirring blade to revolve, and then the stirring shaft and the stirring blade revolve to stir the raw materials, at the same time, the motion track adjusting mechanism changes the revolution radius of the stirring shaft, and then changes the motion track of the stirring shaft and the stirring blade, so that the stirring shaft and the stirring blade move reversely to the reaction barrel shaft or the reaction barrel side wall when revolving, and the stirring shaft and the stirring blade can stir any position in the reaction barrel.

The invention belongs to the field of biological medicine, and particularly relates to a plumbagin isomer PLB-1 as well as a composition and application of the plumbagin isomer PLB-1. The plumbagin isomer PLB-1 and the composition are deeply researched through molecular biology, transcriptome sequencing and animal experiment related experimental means, the specific regulation and control mechanism of the plumbagin isomer to an NQO1 / HO-1 pathway and the specific synergistic effect of HAS-NPs (at) PLB-1 (at) PD-L1 to plumbagin, and the specific regulation and control mechanism of the plumbagin isomer PLB-1 (at) PD-L1 and the specific regulation and control mechanism of the a leading bioinformatics method is combined, a new regulatory pathway of the PLB-1 is explored, and the action effect of the PLB-1 is further improved by taking an albumin nano material as a drug carrier. A new treatment mode is provided for the lung cancer, meanwhile, a new way is provided for application of PLB-1, and breakthrough of fundamental research on treatment of the lung cancer by PLB is achieved.

The utility model discloses a reaction kettle for producing and processing 2-ethyl anthraquinone, which comprises a reaction kettle body and a base arranged on the lower side of the reaction kettle body, a cover is arranged on the upper side of the reaction kettle body, a motor is arranged in the middle of the upper side of the cover, and the motor is connected with the base. The reaction kettle comprises a reaction kettle body, a motor is arranged in the reaction kettle body, heaters are arranged on the left side and the right side of the motor respectively, a stirring shaft is connected to the lower side of the motor, stirring blades are connected to the tail end of the lower side of the stirring shaft, an inner cavity is formed in the inner side of the reaction kettle body, and the motor and the heaters are powered by being connected with an external power source. The heat conduction oil is used as a heat medium and can absorb heat emitted by the heating net more uniformly, local overheating or uneven heating is avoided, the uniformity of the temperature of liquid in the reaction kettle body is ensured, efficient and controllable proceeding of chemical reaction is facilitated, the heating net is completely immersed in the heat conduction oil, effective transfer of heat is ensured, heat loss is reduced, and the service life of the reaction kettle is prolonged. And the heating efficiency is improved.

This invention relates to a class of naphthoquinone derivatives, their preparation, and their application in the prevention and control of plant diseases and pests. This invention is the first to discover that juglone derivatives I-1 to I-13 and lancione derivatives II-1 to II-6 can effectively inhibit 14 plant pathogens, including tobacco mosaic virus (TMV), cucumber wilt, peanut brown spot, apple ring rot, wheat sheath rot, corn small spot, watermelon anthracnose, rice seedling blight, tomato early blight, wheat scab, rice blast, pepper blight, rapeseed sclerotium, cucumber gray mold, and rice sheath rot. Furthermore, it exhibits good activity against eight plant pests: armyworm, cotton bollworm, corn borer, cabbage moth, mosquito larvae, aphids, spider mite, and diamondback moth.

The patent relates to a method for preparing marine terpenoid natural products based on a decarboxylation coupling reaction of carboxylic acid salt of sclareolide or carboxylic acid of sclareolide and quinone compounds, and belongs to the field of chemical synthesis. The method takes sclareolide as raw material, and realizes, for the first time, a Minisci decarboxylation coupling reaction of carboxylic acid salt of bicyclic sesquiterpene or carboxylic acid of sclareolide and p-benzoquinone promoted by Selectfluor, so that the synthesis steps of yahazunone are shortened from the previous 6-18 steps to 2 steps, and asymmetric synthesis of multiple yahazunone natural products is realized. The method has the characteristics of good step economy, simple operation and suitability for industrial production.

The present application relates to the technical field of medicine, in particular to a MK-4 analogue, a preparation method and application thereof. The MK-4 analogue provided by the present application is more stable in liver microsomes and has a longer half-life. In the osteogenic experiment of osteoblasts, the osteogenic ability is stronger, which is of great significance for enhancing the specificity, effectiveness and reducing the side effects of drugs, and thus can be used for preparing drugs for preventing and / or treating osteoporosis. As the MK-4 analogue, it is expected to be used for preparing drugs for treating cardiovascular and cerebrovascular diseases, chronic kidney disease, neurodegenerative diseases, diabetes and cancer, etc.

The invention discloses a supramolecular composite electrode for a dual-carbon target. The supramolecular composite electrode is a copper-plated electrode coated with a column [5] quinone modification layer. The supramolecular composite electrode provided by the invention has a special application mode in CO2 reduction, and shows excellent multi-carbon product selectivity in an acidic electrolyte; the Faraday efficiency of reducing CO2 into a multi-carbon product in a flow-type electrolytic cell is excellent at a CO2 flow rate of 30 mL min <-1 > and a current density of 400 mA cm <-2 >. The supramolecular composite electrode is simple to prepare, has excellent selectivity when being used for electrocatalytically reducing greenhouse gas CO2 into a multi-carbon product in an acidic electrolyte, and has important significance for realizing a dual-carbon target.

According to the research, a novel photooxidation reduction system based on the photochromic Cu-TiO2 nano-catalyst is developed, and efficient activation and selective coupling of C-Cl bonds under visible light driving are successfully achieved. Through a dual reaction path of concerted catalysis of benzyl chloride reduction and phenol oxidation, the system can directionally synthesize C-C / C-O bond drug molecules such as 4-benzyloxyphenol (monobenzone) and benzylated 1, 4-benzoquinone. Mechanism research shows that Cu doping enhances the coordination capacity of a substrate, Cu / Cu active sites generated by excitation of Cu doping have a synergistic effect with oxygen vacancies, the C-Cl bond activation efficiency is remarkably improved, and efficient synthesis of bibenzyl (the yield is gt, 96%, and the selectivity is gt, 99%) is achieved. The photooxidation path can be selectively controlled by regulating and controlling the solvent environment, so that accurate synthesis of high-added-value drugs of different bond type products is realized. The work provides a new thought for developing a high-efficiency photocatalytic drug synthesis system, and has important guiding significance for functional research of C-Cl bonds.

The invention discloses a method for carrying out difluoromethoxy conversion on alcohol, and relates to the technical field of organic chemical synthesis. According to the invention, under mediation of light and acid, hydroxyl of alcohol can react with bpyCu (CF3) 3 to realize difluoromethoxylation; the alcohol difluoromethoxylation reaction provided by the invention has the advantages that the substrate universality is good, the alcohol difluoromethoxylation of primary alcohol, secondary alcohol, tertiary alcohol and even polyhydroxy compounds can be realized, the compound types of the difluoromethoxylation compounds can be expanded, and the full research of the difluoromethoxylation compounds can be further realized.

This invention discloses a method for preparing quinone compounds. The method comprises the following steps: in the presence of a base, a compound as shown in Formula II and a compound as shown in Formula III undergo a condensation reaction to obtain a quinone compound as shown in Formula I; wherein the base is more basic than sodium phenolate. This method is simple to operate and suitable for industrial production.

The application belongs to the field of organic chemical synthesis and medicinal chemistry, and particularly relates to the field of avarane type polycyclic heteroterpene compounds, and discloses that a 6 / 6 fused dienone tertiary alcohol is converted into a spiro[4.5]ene dienone skeleton through a rare stereospecific 1,2-alkyl migration reaction, de-OEt-1'-septosones B and C, 1'-septosones B and C and spiroetherones A and B are synthesized, and the structures of spiroetherones A and B are modified. Meanwhile, biological activity tests on the synthetic intermediates find that two new compounds exhibit significant anti-cancer activity on Hep G2, MV-4-11 and MOLT-4 cell lines, and IC epi values are as low as 2.1 μM. The application provides a new way and compound basis for the research and application of related heteroterpene compounds. epi values are as low as 2.1 μM. The application provides a new way and compound basis for the research and application of related heteroterpene compounds. 50 values are as low as 2.1 μM. The application provides a new way and compound basis for the research and application of related heteroterpene compounds.

The invention belongs to the technical field of organic compound preparation, and particularly relates to a method for continuously preparing 2-ethyl anthraquinone. The preparation method comprises the following steps: S1, loading an MOF / phosphotungstic acid composite catalyst on the inner wall of a reaction tube of a continuous reactor for later use; s2, taking phthalic anhydride and ethylbenzene as raw materials, and performing Friedel-Crafts acylation, acidolysis and purification to prepare 2-(4-ethylbenzoyl) benzoic acid; s3, in the continuous reactor, under the action of the MOF / phosphotungstic acid composite catalyst, 2-(4-ethylbenzoyl) benzoic acid is subjected to dehydration and ring closing, and 2-ethyl anthraquinone is prepared. By combining the photosensitive ligand, MOF and phosphotungstic acid, the catalytic reaction efficiency and selectivity of 2-ethyl anthraquinone are improved; by optimizing the preparation process of the 2-ethyl anthraquinone, the operation is simplified, the generation of waste acid is reduced, and green and clean, high yield, good production safety and continuous production in the synthesis process of the 2-ethyl anthraquinone are realized.

The application belongs to the field of medicine synthesis, and specifically provides a daunorubicin intermediate compound. The daunorubicin can be synthesized by pure chemical synthesis by using the intermediate compound. The daunorubicin is synthesized by taking 2,5-dihydroxybenzyl alcohol as a raw material. The route has low raw material cost, mild reaction condition, convenient post-treatment, high total yield, and good industrial application prospect.

The utility model discloses an energy-saving 2-ethyl anthraquinone production heat exchanger which comprises a reaction kettle, the front side and the rear side of the center of the upper end of the reaction kettle are both communicated with feeding pipes, a stirring motor is arranged at the center of the upper end of the reaction kettle, a stirring shaft is rotationally connected to the center of the lower end of the stirring motor and located in the reaction kettle, and the stirring shaft is connected with a motor. The front side of the center of the lower end of the reaction kettle is communicated with a discharging pipe, a heating mechanism is arranged in the center of the lower end of the reaction kettle, the upper end of the heating mechanism is located in the reaction kettle, the lower end of the heating mechanism is connected with a power source through a wire harness, and a plurality of supporting legs are fixedly connected to the outer side of the lower end of the reaction kettle. The heat preservation recovery chamber is arranged in the cylindrical inner wall of the reaction kettle and is communicated with the interior of the reaction kettle through a plurality of communicating holes, in the purification process, evaporated high-temperature steam is guided into the heat preservation recovery chamber to preserve heat of the reaction chamber, heat loss is prevented, reutilization of the high-temperature steam is achieved, and energy conservation and consumption reduction are achieved.

The invention relates to the technical field of organic synthesis, and particularly discloses a synthesis method of 2, 3-dimethyl-1, 4-dihydronaphthalene-1, 4-diketone. The invention relates to a synthesis method of 2, 3-dimethyl-1, 4-dihydronaphthalene-1, 4-diketone, which comprises the following steps: mixing menadione, concentrated sulfuric acid, ferrous sulfate and an organic solvent to obtain a mixed solution; tert-butyl hydroperoxide is added into the mixed solution at the temperature of 80-120 DEG C under the nitrogen protection atmosphere, stirring reaction is conducted for 1-15 h, and reaction liquid is obtained; after the reaction liquid is subjected to post-treatment, the 2, 3-dimethyl-1, 4-dihydronaphthalene-1, 4-diketone is obtained. The synthesis method of the 2, 3-dimethyl-1, 4-dihydronaphthalene-1, 4-diketone, disclosed by the invention, has the advantages of simple and convenient steps, simplicity in operation and low cost of adopted raw materials, and is suitable for large-scale production.

The application belongs to the technical field of organic compound preparation, and particularly relates to a method for continuously preparing 2-ethylanthraquinone. The preparation method comprises the following steps: S1, loading a MOF / phosphotungstic acid composite catalyst on the inner wall of a reaction tube of a continuous reactor for standby; S2, using phthalic anhydride and ethylbenzene as raw materials, performing a Friedel-Crafts acylation, acidolysis and purification to prepare 2-(4-ethylbenzoyl)benzoic acid; and S3, in the continuous reactor, 2-(4-ethylbenzoyl)benzoic acid is subjected to dehydration and ring closure under the action of the MOF / phosphotungstic acid composite catalyst to prepare 2-ethylanthraquinone. The application combines a photosensitive ligand, a MOF and phosphotungstic acid to improve the catalytic reaction efficiency and selectivity of 2-ethylanthraquinone. Through optimization of the preparation process of 2-ethylanthraquinone, the operation is simplified, waste acid generation is reduced, and green cleaning, high yield, good production safety and continuous production are realized in the synthesis process of 2-ethylanthraquinone.

The invention belongs to the technical field of veterinary drugs, particularly relates to a preparation method of a 2, 3-disubstituted naphthoquinone compound for preventing and treating animal ectoparasites, and aims to solve the problem that a preparation method of related compounds convenient for industrialization is lacked in the prior art. According to the preparation method, different reaction general formulas are matched with differentiated preparation processes, so that the performance of the finally prepared compound is ensured; the preparation method disclosed by the invention is simple in process and mild in reaction condition, diverse 2, 3-disubstituted naphthoquinone compounds can be efficiently prepared, and the prepared compounds have high fatality rate on various animal ectoparasites and are convenient for industrial popularization and synthesis.

The invention relates to the technical field of antibacterial drugs, and particularly discloses a preparation method and application of a novel lipophilic gallium complex with activity. A preparation method of a novel lipophilic gallium complex with activity comprises the following steps: firstly, mixing Ga (NO3) 3.9 H2O and 2-hydroxy-3-methyl-1, 4-naphthoquinone in a 90% ethanol solution containing K2CO3, then stirring at room temperature for 3 hours for synthesis reaction, then filtering and collecting red solid filter residues, then washing with ethanol for 3 times, and drying in a vacuum oven to obtain the novel lipophilic gallium complex with activity. The molecular formula of the complex is C33H21O9Ga. The novel lipophilic gallium complex with activity provided by the invention can be used for preparing a medicine for resisting gram-negative bacteria, and has the advantages of efficient antibacterial activity and capability of effectively inhibiting the formation of a biological membrane and eradicating a mature biological membrane; in addition, the preparation method disclosed by the invention has the advantages of simplicity and convenience in operation, mild conditions and high product purity.

To realize synthetic functionalization of anthraquinone molecules substituted with at least one hydroxyl group or amino group.SOLUTION: According to part of embodiments of the present invention, synthetic functionalization of anthraquinone molecules occurs not chemically but electrochemically by using a divided electrolytic tank.SELECTED DRAWING: Figure 2