301 results about "Oxime" patented technology

The invention relates to the field of caprolactam production, and discloses a green and efficient production process and device. The process comprises the following steps: continuously oximating cyclohexanone and hydroxylamine in a microreactor under the catalysis of mesoporous silica solid acid; carrying out gas phase rearrangement on cyclohexanone-oxime in the presence of a ZSM-5 molecular sieve under the assistance of microwaves; coupling, rectifying and purifying the crude product through a four-stage molecular sieve membrane; and performing catalytic cracking on the by-product to obtain N2 / H2O and recycling. The device comprises a micro-reaction unit, a microwave-radial reactor, a membrane coupling rectifying tower group and a tail gas cracking unit. Zero emission of ammonium sulfate is achieved, the product purity is larger than or equal to 99.95%, and energy consumption is reduced by 45%.

The invention belongs to the technical field of organic synthesis, and relates to a preparation method of 5, 5-dimethyl-4, 5-dihydroisoxazole. The method comprises the following steps: (1) reacting isopentenal with an oximation agent to obtain a reaction solution containing isopentenal oxime; (2) dropwise adding the reaction liquid into a mixture containing isopentenal and an acid catalyst for reaction to obtain a product; or when the reaction liquid contains water, performing phase splitting on the reaction liquid to obtain an organic phase, and dropwise adding the organic phase into a mixture containing the isopentenal and the acid catalyst for reaction to obtain a product. The method does not produce ketone by-products, and is good in atom economy, high in reaction yield, good in technological process continuity, low in cost, few in materials, simple to operate, mild in reaction condition, low in requirements on production equipment and suitable for large-scale industrial production.

The invention provides an epoxy adhesive solution composition, a preparation method of an epoxy adhesive solution and a modified cellular board. The epoxy adhesive liquid composition comprises the following components in parts by weight: 53-58 parts of epoxy resin, 2-10 parts of a silane coupling agent, 1-10 parts of a curing agent, 1-5 parts of blocked isocyanate and 60-70 parts of water, wherein a blocking group of the blocked isocyanate is selected from hydroxyl, oximido, acylamino, amino, imidazolyl, pyrazolyl or piperazinyl. By introducing the blocked isocyanate with the specific structure, the epoxy adhesive liquid can be subjected to pre-crosslinking reaction in the early drying treatment process, the modulus and high temperature resistance of a formed dry film are improved, and the phenomenon of glue overflow in the subsequent curing stage is inhibited; therefore, the structural integrity and the bonding strength of the adhesive layer in the modified cellular board under the high-temperature condition are improved.

The invention belongs to the technical field of photoinitiators, and particularly relates to an oxime ester photoinitiator, a photoresist composition and application of the oxime ester photoinitiator and the photoresist composition. The initiator provided by the invention is an oxime ester compound, the main structure of the photoinitiator molecule has the capability of absorbing light with different wavelengths, the molecular stability is good, meanwhile, the blue light absorption is reduced, and the yellowing risk of the system is inhibited. Through substituent group modification, on the premise that the stability of the photoinitiator is improved, the light absorption activity and initiation efficiency of the photoinitiator can be guaranteed, the photocuring reaction is efficiently promoted, the dual requirements of production for speed and quality are met, and collaborative optimization of absorption wavelength expansion, stability improvement and initiation efficiency guarantee is achieved.

The invention relates to a synthesis method of 5, 5-disubstituted 2-isoxazoline, according to the method, oxime of a formula (II) and a carbonyl compound of a formula (I) react in the presence of a boron trifluoride complex and in the presence of an optional organic solvent or no solvent, the reaction conditions are mild, and the product yield is high.

The invention discloses a synthesis method of 9-dichloromethylene-5-amino-benzonorbornene and an intermediate product, the synthesis method comprises the following steps: firstly, synthesizing a cyclization compound 1 as shown in a formula 1 from a cold solution of 6, 6-dichlorofulvene and 1, 4-benzoquinone under the action of a solution of a catalyst I, carrying out oximation reaction on the cyclization compound 1 prepared in the step a and hydroxylamine salt under an alkaline condition, and carrying out post-treatment to obtain the 9-dichloromethylene-5-amino-benzonorbornene. Under the action of a catalyst II, adding the oximate 2 prepared in the step b into a closed container, carrying out hydrogenation reduction to obtain 9-dichloromethylene-5-amino-benzo norbornene, and directly treating the reduction product with acid to obtain 9-dichloromethylene-5-amino-benzo norbornene, namely the 9-dichloromethylene-5-amino-benzo norbornene, namely the 9-dichloromethylene-5-amino-benzo norbornene. According to the method, the cyclization compound is oximated firstly, then the residual carbonyl and two double bonds on the ring are subjected to one-step reduction through catalytic hydrogenation, the working procedure is optimized, meanwhile, reduction by using expensive sodium borohydride is avoided, the method is short in synthesis route and suitable for industrialization, and the production cost is reduced.

Described herein are compounds that reactivate acetylcholinesterase and associated methods of treating organophosphate poisoning.

This invention provides a dehydrogenation catalyst that enables the production of hydrogen by dehydrogenating formic acid using a continuous process with higher efficiency than conventional methods, as well as a polymer precursor that can optimally form the catalyst and a formic acid dehydrogenation catalyst formed therefrom. [Solution] The polymer precursor has a structure represented by the following general formula (1). TIFF2026073992000060.tif50163 (A and B are independently groups comprising a 5-membered or 6-membered heterocycle or oxime structure which may have substituents, Z is a 5-membered or 6-membered aromatic ligand, M is a Group 8 noble metal element, R 1 R is a hydroxyl group, an alkenyl group or alkynyl group having 1 to 12 carbon atoms, 2 (where is a halogen atom, hydrogen atom, formic acid, or water molecule, X is an anion, and n is a natural number between 1 and 12)

The present application relates to a kind of phenyl-tetrazole oxime derivatives and its preparation method and application, wherein the phenyl-tetrazole oxime derivatives have the structure as shown in formula (I), wherein R 1 , R 2 , T, R a , R b , R c , R d , R e Have the meaning described in the present application;The phenyl-tetrazole oxime derivatives described in the present application have excellent prevention effect on cucumber downy mildew, rice sheath blight, cucumber gray mold, cucumber powdery mildew and the like, and can be further developed as a fungicide for application.

The invention relates to the technical field of organic chemistry, and particularly discloses an amide derivative containing a thiazole oxime structure as shown in a general formula 8 and a preparation method and application of the amide derivative. The derivative shows remarkable antibacterial activity on staphylococcus aureus, escherichia coli, pseudomonas aeruginosa and fluoroquinolone-resistant escherichia coli, particularly has a remarkable effect on gram-negative bacteria, has broad-spectrum antibacterial potential and can be used for preparing drugs for treating related bacterial infection, and the activity of part of compounds is superior to that of a control drug.

The invention discloses a liquid phase detection method of an oxime ester photoinitiator, and relates to the field of chemical analysis and detection. According to the method, a standard solution, a reaction solution to be detected and a mobile phase are prepared, a sample to be detected is subjected to pretreatment such as quenching and extraction, a high performance liquid chromatography gradient elution technology is combined to realize detection, the mobile phase adopts a phosphoric acid aqueous solution with the concentration of 0.05-0.1% and acetonitrile, a gradient elution program optimizes the separation effect, and a chromatographic column adopts a C18 stationary phase. According to the method, the separation degree of the impurities such as diester impurities in the oxime ester photoinitiator synthesis reaction is larger than or equal to 1.5, the detection limit is as low as 0.010 mg / L, the quantification limit is as low as 0.032 mg / L, the reaction process can be effectively monitored, and the method has the advantages of being easy and convenient to operate, low in cost and high in accuracy.

The invention provides an aryl alkyl ketoxime derivative as well as a preparation method and application thereof, and relates to the field of aryl oxime derivatives. The preparation method of the aryl alkyl ketoxime derivative comprises the following steps: by taking potassium formate as an additive, carrying out free radical reaction on a compound I and a compound II under ultraviolet irradiation in the presence of tert-butyl nitrite to obtain the aryl alkyl ketoxime derivative, the compound I is substituted iodobenzene or iodopyridine; the compound II is substituted styrene or thienyl ethylene; wherein a hydrogen atom transfer / single electron transfer relay sequence is utilized to activate a compound I, and tert-butyl nitrite is adopted as a bifunctional reagent, and is used as a hydrogen atom transfer reagent and an oxime source. According to the preparation method of the aryl alkyl ketoxime derivative, pre-functionalization is not needed, a reaction substrate is wide in universality and good in compatibility, reaction conditions are mild, operation is easy and convenient, a target product can be efficiently and rapidly prepared on the premise of high yield, and a new way is provided for oxime synthesis.

The problem to be solved is to provide a novel herbicide having both high safety for crops and excellent herbicidal activity against weeds in order to resolve the food crisis that is anticipated to come in the near future due to global population growth. The problem is solved by the compound represented by the following general formula (1): or a salt thereof, an agricultural or horticultural herbicide comprising the compound or the salt thereof as an active ingredient, and a method for using the herbicide.

Provided are new compounds that are free of perfluoromethyl and perfluoromethylene groups, are easily decomposed by light irradiation, and generate sulfonic acid having high acid strength.　The present invention is a compound that is a salt of an anion represented by formula (a-1) or (a-2) and a cation. In the formula, R1 represents a hydrogen atom, a hydrocarbon group, or a heterocyclic group, or a group in which two or more of said groups are bonded via a linking group. R10 represents a fluorine atom, an aromatic hydrocarbon group, or an aromatic heterocyclic group. R20 represents a hydrogen atom, a halogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group, or a group having a group in which said group and a linking group are bonded. n is 0 or 1.

The application relates to a method for preparing a beta-heteroaryl ethylamine derivative by utilizing photocatalytic energy transfer, and belongs to the technical field of catalytic synthesis, in particular to a method for preparing a beta-heteroaryl ethylamine derivative by utilizing photocatalytic energy transfer. The application is to solve the technical problems of the existing synthesis method, such as being too complicated, needing pre-activation and expensive metal catalysts. One, an oxime ester compound, an olefin compound and TXT are added into a solvent to obtain a mixed solution; two, the mixed solution obtained in the step one is irradiated by using an LED light source, the solvent is removed by rotary evaporation, and separation and purification are carried out. Compared with the prior art, the application is more green, mild, atom-economical, simple and efficient in a metal-free catalytic energy transfer strategy to construct aryl tertiary amine compounds. The method can be used for preparing a beta-heteroaryl ethylamine derivative.

Disclosed in the present invention are a method and system for preparing an oxime via an ammoximation reaction. The method comprises: (1) mixing a carbonyl compound, ammonia, and a circulating catalyst slurry at a specific feed ratio of the carbonyl compound to the circulating catalyst slurry to obtain a mixed stream, and then bringing the mixed stream into contact with hydrogen peroxide for an ammoximation reaction to obtain a reaction slurry; (2) mixing the reaction slurry with an organic solvent and then performing two-phase separation to obtain an oxime-containing organic phase and a catalyst-containing aqueous phase; (3) optionally, washing the organic phase obtained in step (2) with optional water and then performing separation to obtain an organic solvent and an oxime product; and (4) filtering the aqueous phase obtained in step (2) and then returning same to step (1) to provide at least part of the circulating catalyst slurry. The method and system for preparing an oxime according to the present invention significantly prolong the service life of a catalyst, improve the operating stability of a system, reduce the consumption of catalyst, and improve the quality of the prepared oxime product.

The invention discloses a preparation method of pesticide line thiophene, which comprises the following steps: under protective gas, dissolving benzaldoxime and 2-cyano thiophene in an organic solvent, slowly adding an oxidizing agent at the temperature of 20-30 DEG C, and after the reaction is completed, washing with water, extracting, concentrating and recrystallizing to obtain line thiophene, the oxidizing agent is selected from one or more of diacetoxy iodobenzene, [bis (trifluoroacetoxy) iodine] benzene and potassium peroxymonosulfonate. According to the preparation method of the pesticide line thiophene, the line thiophene is directly and efficiently synthesized through one-step reaction, and the yield is good. Compared with the existing synthesis route, the route is short, the solvent can be recycled and reused, the requirement on equipment is simple and corrosion-free, and a foundation is laid for further pilot scale production.

The application discloses a synthesis method of 5,5-dimethyl 2-isoxazoline. First, isoamyl aldehyde is added with hydrogen chloride to generate chloroisoamyl aldehyde, then under alkaline conditions, the chloroisoamyl aldehyde generated in step one is added with hydroxylamine salt to generate chloroisoamyl aldehyde oxime, finally under alkaline conditions, the chloroisoamyl aldehyde oxime generated in step two is cyclized to generate 5,5-dimethyl 2-isoxazoline, the yield is high, the process is simple and suitable for industrial production; compared with the traditional method, the synthesis method has the characteristics of mild reaction condition, green environmental protection and low cost.

The invention discloses a method for co-production of 2, 4-dichloro-5-fluoroacetophenone and hydroxylamine hydrochloride, and belongs to the technical field of organic chemical industry, 2, 4-dichlorofluorobenzene is used as a raw material, alkylation and reaction with tert-butyl nitrite are performed to generate oxime, and then hydrochloric acid hydrolysis is performed to generate 2, 4-dichloro-5-fluoroacetophenone and hydroxylamine hydrochloride; according to the method, co-production of the 2, 4-dichloro-5-fluoroacetophenone and the hydroxylamine hydrochloride is innovatively realized, not only are high yield and high purity of the target product 2, 4-dichloro-5-fluoroacetophenone ensured, but also the nitrogen element in the reaction is recycled and converted into the hydroxylamine hydrochloride with high additional value, and the atom economy is remarkably improved; according to the method, the operation process is greatly simplified, the use of dangerous reagents is avoided, and the intrinsic safety and environmental friendliness of the process are improved from the source; the method is simple to operate, safe and environment-friendly, the production cost is effectively reduced, and the market competitiveness of the product is enhanced.

The application provides a purification process method and device of a lactam, wherein an oxime is subjected to a rearrangement reaction with a catalyst, the obtained lactam is purified after the rearrangement reaction, and the method comprises the following steps: extracting the lactam by using an extraction solvent to obtain a lactam solution from which the catalyst is separated, performing alkali washing and water washing on the obtained lactam solution to obtain a lactam solution after alkali washing and water washing, performing hydrogenation reaction on the obtained lactam solution again, performing crystallization separation on the lactam solution after hydrogenation to obtain a lactam product crystal, and then performing treatment on the obtained lactam product crystal by means of solvent washing, rectification, distillation or crystallization to obtain the lactam with a purity of greater than or equal to 99.9%.

The invention provides a preparation method of acacia gum nano-composite hydrogel. The preparation method comprises the following steps: S1, mixing an acacia gum aqueous solution with a free radical initiator, and then sequentially adding acrylonitrile, CuFe2O4 nanoparticles and a cross-linking agent into the mixture to obtain the acacia gum nano composite hydrogel. The acacia gum nano-composite hydrogel combines the characteristics of a natural polymer, a synthetic polymer and inorganic nanoparticles, and is an effective adsorbent for removing heavy metals in an aqueous solution, the prepared magnetic hydrogel is treated by hydroxylamine hydrochloride, so that a nitrile group is converted into an amidoxime group to serve as a bidentate ligand, and the adsorption capacity of the hydrogel is improved. The existence of CuFe2O4 in the acacia gum nano-composite hydrogel makes the recoverable magnetic hydrogel possible, the recoverable magnetic hydrogel can be easily removed from an aqueous solution and regenerated, and after three continuous cycles, the recoverable magnetic hydrogel still has high heavy metal adsorption capacity.

The invention relates to the technical field of flocking adhesives, in particular to a high-performance single-component flocking adhesive and a preparation method thereof.The high-performance single-component flocking adhesive is at least prepared from, by mass, 40-60% of blocked polyurethane, 5-15% of phenol novolac epoxy resin, 0-5% of aromatic nitroso compounds, 0-5% of imine compounds and the balance solvent, the closed polyurethane has an oxime carbamate structure, the weight-average molecular weight is 60000-90000, by optimizing a product formula system, the problems of poor wear resistance, poor solvent resistance and the like after an adhesive is coated are effectively solved, meanwhile, the operation is convenient and fast, the efficiency is high, the application scene and the application range of the adhesive are expanded, and the market demand is better met.

This invention relates to the field of chemical analysis technology, specifically to an analytical method for the content of 1,1-dibromoformaldehyde oxime. The method includes the following steps: (1) dissolving the standard and the sample to be tested separately in acetonitrile to prepare standard solutions and sample solutions; (2) setting the analytical conditions of the high-performance liquid chromatograph (HPLC), and after the instrument baseline stabilizes, injecting the standard, sample to be tested, sample to be tested, and standard in sequence, calculating the average peak area of ​​1,1-dibromoformaldehyde oxime in the standard solution and sample solution respectively; (3) calculating the mass fraction of 1,1-dibromoformaldehyde oxime in the sample to be tested according to the external standard method formula. The analytical method of this invention has strong specificity, good precision, high reliability, and good repeatability, and is particularly suitable for the content analysis of 1,1-dibromoformaldehyde oxime products and for mid-control analysis during the synthesis reaction process.

This invention relates to the field of polymer materials technology, and discloses a lignin-based adsorbent modified with a methylamine oxime, its preparation method, and its application. The invention uses lignin enzymatically hydrolyzed solid waste from industrial ethanol production as raw material. Utilizing the phenolic hydroxyl activity of lignin, methylamine oxime functional groups are chemically grafted onto the lignin structure to obtain a lignin-based adsorbent modified with a methylamine oxime. This adsorbent has the advantages of strong stability, high adsorption activity, low cost, and recyclability, enabling the high-value utilization of waste enzymatically hydrolyzed lignin. When the above-mentioned lignin-based adsorbent is used in the treatment of highly acidic uranium-containing nuclear wastewater, the uranium adsorption rate can reach up to 99.9%, which is beneficial for the promotion of lignin-based materials in the industrial application of treating highly acidic nuclear wastewater.

The invention belongs to the field of organic small molecule synthesis, and particularly relates to a synthesis method of a biphosphamide compound, the structural formula of the biphosphamide compound is shown in the specification, and the synthesis method comprises the following steps: by taking N, N-dimethylformamide (DMF) as a reaction solvent, under the action of an oxidizing agent and acid, carrying out a reaction on the reaction solvent to obtain the biphosphamide compound. And carrying out a free radical mediated deoxidation double phosphating reaction with an equivalent amount of phosphine oxide compound to obtain the bisphosphamide compound. Wherein Ar is aryl, A is a straight chain or a 5-7-membered ring, R is hydrogen, alkyl or aryl, and R'is alkyl or aryl. According to the method, equivalent oxime and phosphine oxide compounds are taken as reactants, under the action of cheap protonic acid and oxidizing agent, the synthesis of the deoxidized double phosphating product biphosphamide compound can be economically and efficiently realized, and the method is good in substrate universality, mild in reaction condition, simple in process, safe and easy to operate.

The invention discloses a fluorine-containing ionic type dynamic cross-linked polyurethane elastomer and a preparation method thereof. The fluorine-containing ionic type dynamic cross-linked polyurethane elastomer is prepared from polyether / polyester glycol, a dioximido ion-containing chain extender, isocyanate, a catalyst and a cross-linking agent through in-situ polymerization reaction. According to the invention, an ionic polyurethane covalent adaptive network is prepared through a pre-polymerization-chain extension-cross-linking reaction of a dioximido ion-containing chain extender, polyether, isocyanate, a catalyst and a cross-linking agent. The thermodynamic incompatibility between a soft segment and a hard segment is remarkably improved through the ionic interaction between molecular chains in the network, microphase separation enhancement is promoted, the hard domain serves as a physical crosslinking site to provide strength support, and the soft domain endows the material with flexibility and extensibility; under the action of external force, multiple hydrogen bonds and ions in a hard domain interact to generate dynamic dissociation and association, and a remarkable energy dissipation effect is realized, so that compared with a traditional polyurethane dynamic adaptive network, the polyurethane dynamic adaptive network shows synergistic improvement of strength and toughness, and keeps excellent thermal mechanical stability and environmental resistance in a service environment.

The invention belongs to the technical field of organic synthesis, focuses on innovation of a preparation method of an organic germanium compound, and particularly provides a novel photochemical synthesis path of an alpha-germanium oxime compound. According to the method, germane hydride, olefin and tert-butyl nitrite are taken as starting raw materials, and under the condition that no photocatalyst is added, only an ultraviolet light source is utilized for irradiation, so that the germanium-based / oximido-based bifunctionalization reaction of olefin is successfully realized for the first time. The method has the advantages of environmental friendliness, mild conditions, simplicity and convenience in operation, high atom economy, wide substrate application range and the like. The method can be used for modifying the drug molecule derivative after germanium group / oximidation, opens up a way for constructing an organic germanium compound with potential biological activity and pharmacological action, and is expected to play an important role in the field of medicine research and development.

This invention discloses a method for preparing dodecanoic acid lactam, comprising an oximation reaction of cyclododecanone, a rearrangement reaction of cyclododecanone oxime, and extraction and purification. The oximation reaction of this invention uses a cobalt-based MOF catalyst, which has high catalytic activity and can significantly improve the conversion rate of the cyclododecanone oximation reaction, thereby improving the overall reaction efficiency, reducing the formation of by-products, and thus improving the purity of the target product. In the rearrangement reaction of cyclododecanone oxime, zirconium oxide sulfate is used as a catalyst. This catalyst has good catalytic performance under high temperature conditions and can effectively promote the rearrangement reaction. Simultaneously, the ionic liquid is used as a solvent, which not only has good solubility but is also environmentally friendly and easy to recycle, reducing production costs and environmental impact.

This invention relates to a phosphate-containing chiral diastereomeric oxime ester compound, its preparation method, and its applications, belonging to the field of organic synthesis technology. This invention introduces a chiral center at a specific location in the molecular structure of the oxime ester compound to form a mixture of diastereomeric stereoisomers. The introduction of the chiral center interferes with intermolecular chiral recognition, thereby effectively suppressing the π-π stacking effect and crystal growth between the aromatic ring cores. Furthermore, the introduction of the phosphate ester structure into the product effectively improves its solubility in propylene glycol methyl ether acetate or cyclohexanone solvents. The photocurable ink prepared using the diastereomeric oxime ester compound of this invention exhibits excellent storage stability and better photosensitivity.

The invention provides a polymer compatilizer and application thereof, and relates to the technical field of organic materials. Specifically, a molecular chain of the polymer compatilizer comprises a polyolefin chain segment, a reversible covalent bond group and an active functional group which are connected in sequence; wherein the reversible covalent bond group comprises at least one of a cycloaddition reaction system, a disulfide bond system, a borate bond system, an acylhydrazone bond system, an oxime bond system, a trithiocarbonate bond system and a tetrazole-olefin light click chemical system. According to the compatilizer structure, a dynamic covalent cross-linked network can be constructed at the interface of the composite material, and the interface is endowed with an intelligent response characteristic through fracture and recombination of reversible covalent bonds, so that the interface bonding strength of the composite material is far higher than that of a traditional system; the technical problems that in the material service process in a traditional system, due to permanent covalent bonding, an interface is prone to being damaged and cannot be reversibly repaired are effectively solved.