2 results about "Azithromycin" patented technology

The application discloses a hydroxylamine hydrochloride detection method in azithromycin dry suspension, and relates to the trace detection field. The method uses isoamyl aldehyde as a derivatizing agent, generates isoamyl aldoxime by performing derivatization treatment on a sample to be measured, and then uses N-nitrosodiisopropylamine as an internal standard substance to quantitatively determine the isoamyl aldoxime by using liquid chromatography-tandem mass spectrometry. The detection method adopts an isoamyl aldehyde derivatizing agent-N-nitrosodiisopropylamine internal standard substance system, can correct detection errors caused by factors such as matrix effect, pretreatment loss and derivatization efficiency fluctuation, and improves the accuracy and sensitivity of the trace hydroxylamine hydrochloride detection result, thereby guaranteeing the safety of the medicine.

This invention discloses an azithromycin dispersible tablet preparation system, including a fixed platform, a sliding platform slidably connected to the upper end of the fixed platform, guide rails fixed on the front and rear sides of the left side of the upper end of the sliding platform, and a tableting mold fixed on the upper side between the guide rails. The tableting mold has a mold hole on its upper side. By moving the sliding plate below the tableting mold, the sliding plate can provide support during the tableting of powdered azithromycin. After tableting, the screw is driven by a screw motor to rotate, and the screw is threadedly connected to the sliding plate, causing the sliding plate to move to the right away from directly under the tableting mold. Then, the hydraulic cylinder moves the tableting plate down, pushing the formed azithromycin dispersible tablet onto the sliding platform. Then, the sliding plate moves to the left and slides under the tableting mold, which pushes the azithromycin dispersible tablet on the sliding platform to the right away from directly under the tableting mold. This eliminates the need for manual removal of the formed azithromycin dispersible tablet, saving manpower.