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3584results about "Pharmaceutical product form change" patented technology

Oral drug compliance monitoring using radio frequency identification tags

A device useful for oral drug delivery device consisting of: (a) a capsule, tablet or pill designed to disperse in the gastrointestinal system; (b) an RFID tag positioned in the capsule, tablet or pill, the RFID tag comprising an antenna; (c) an object selected from the group consisting of a magnet, a ferromagnetic object, a ferrite object and an electromagnetic shielding object positioned within, over or adjacent the antenna of the RFID tag to alter the antenna characteristics of the RFID tag so that if the RFID tag is interrogated before the capsule, tablet or pill disperses in the gastrointestinal system, the response of the RFID tag is sufficiently altered or attenuated to determine that the capsule, tablet or pill has not dispersed in the gastrointestinal system and so that if the RFID tag is interrogated after the capsule, tablet or pill has dispersed in the gastrointestinal system, the object separates from the RFID tag so that the response of the RFID tag is sufficiently detectable to determine that the capsule, tablet or pill has dispersed in the gastrointestinal system. Alternatively, a switch can be used to signal ingestion of the device, and change the response of the device. In another embodiment, the instant invention is a device useful for oral drug delivery, consisting of: (a) a capsule, tablet or pill designed to disperse in the gastrointestinal system; (b) a first non-anti-collision RFID tag positioned in the capsule; (c) a second non-anti-collision RFID tag positioned in the capsule, so that if the RFID tags are interrogated by an RFID reader before the capsule, tablet or pill disperses in the gastrointestinal system, the response of the RFID tags collide and so that after the dispersible material of the capsule has dispersed in the gastrointestinal system thereby allowing the first and second non-anti-collision tags to separate from each other, then the response of the RFID tags is sufficiently different from each other to determine that the capsule has dispersed in the gastrointestinal system
Owner:DOW GLOBAL TECH LLC

Method for electrostatically depositing a medicament powder upon predefined regions of a substrate

Method for electrostatically depositing select doses of medicament powder at select locations on a substrate. Specifically, the apparatus contains a charged particle emitter for generating charged particles that charge a predefined region of a substrate and a charge accumulation control circuit for computing the amount of charge accumulated upon the substrate and deactivating the emitter when a selected quantity of charge has accumulated. Additionally, a triboelectric charging apparatus charges the medicament powder and forms a charged medicament cloud proximate the charged region of the substrate. The medicament particles within the medicament cloud electrostatically adhere to the charged region. The quantity of charge accumulated on the substrate at the predefined region and the charge-to-mass ratio of the medicament powder in the cloud control the amount (dose) of medicament deposited and retained by the substrate. Consequently, this apparatus accurately controls both medicament dosage and deposition location. Furthermore, since the substrate can be of any dielectric material that retains an electrostatic charge, the apparatus can be used to deposit medicament on substrates that are presently used in oral medicament consumption, e.g., substrates that are used to fabricate suppositories, inhalants, tablets, capsules and the like.
Owner:DELSYS PHARMA

Dispensing and injection system for radiopharmaceuticals

InactiveUS20050203329A1Enhanced Radiation ProtectionEasy to effect automatic controlIn-vivo radioactive preparationsInfusion devicesSaline waterRadiation shield
Disclosed is a dispensing and injection system for radiopharmaceuticals, wherein a dosage calibrator is arranged inside a radiation-shielded hermetic chamber for detecting the radioactivity of radiopharmaceuticals contained in a vial. At least one saline water cartridge is arranged inside the casing and includes an internal passage, radiopharmaceuticals discharge end, a radiopharmaceuticals injection end, a and saline water reservoir outlet end. The saline water cartridge forms a saline water reservoir. A movable dispensing and injection mechanism controls radiopharmaceuticals dispensing operation of a syringe and controls movement of the syringe between a radiopharmaceuticals dispensing position and an injection position. When the movable dispensing and injection mechanism moves the syringe to the radiopharmaceuticals dispensing position, the syringe withdraws a predetermined amount of radiopharmaceuticals from the vial. When moved to the injection position, the syringe injects the withdrawn radiopharmaceuticals into the radiopharmaceuticals injection end of the saline water cartridge. After the radiopharmaceuticals is injected into a patient, the saline water stored in the saline water reservoir of the saline water cartridge is withdrawn for effecting flushing process.
Owner:SHIH CHI DAU
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