The invention relates to the technical field of
radiation resistance, and particularly discloses a preparation method of
siraitia grosvenorii extract dry paste and application of the
siraitia grosvenorii extract dry paste in
radiation damage resistance, the preparation method of the
siraitia grosvenorii extract dry paste comprises the following steps: taking dried
siraitia grosvenorii, breaking the
siraitia grosvenorii into pieces, putting the broken
siraitia grosvenorii pieces into a
medicine decocting pot, extracting the siraitia grosvenorii pieces in 1-3 times by adopting a decoction method, adding 8-12 times of water each time, decocting for 0.5-1.5 h, filtering, and concentrating the filtrate to obtain the siraitia grosvenorii extract dry paste. Filtering with double-layer gauze, combining filtrates, heating, evaporating and concentrating, and
drying in vacuum to obtain the fructus momordicae extract dry paste. Secondly, a < 60 > Co
gamma ray induced light
radiation injury mouse model is established, the mouse
body weight growth rate, the anti-fatigue ability, the
peripheral blood cell level, the visceral index and the immune related
factor level are improved through treatment with the fructus momordicae extracting solution, the
recovery effect on
radiation induced immune injury and function decline is achieved, and the good effect of resisting
radiation injury is achieved.