17 results about "Macleaya cordata" patented technology

The invention discloses a benzofuran glycoside compound as well as a separation and extraction method, a pharmaceutical composition and application thereof. The compound 1 is separated from an eupatorium chinense extract. And separating and purifying chemical components of the n-butyl alcohol part of the eupatorium chinense root to obtain the benzofuran compound. The inhibition activity of target cyclooxygenase-2 of inflammatory related diseases of all the separated compounds 1 is tested, and the compounds 1 have good inhibition activity on COX-2 enzyme and have good binding energy with target protein. In addition, the compound also has a good NLRP3-related inhibition effect, can be independently used or combined with other medicines to regulate NLRP3-related proteins, and is used for treating NLRP3-related mediated diseases and / or diseases and preparing medicines for preventing or treating the diseases or diseases. The compound 1 also has a good inhibition effect on acetylcholin esterase, and can be used for treating Alzheimer's disease, myasthenia gravis, Parkinson's disease and other diseases.

The invention provides application of a macleaya cordata extract as a plant source algaecide in cyanobacterial bloom treatment, and relates to the technical field of plant source algaecide product development and environmental protection. The total alkali content of the macleaya cordata extract is 50-80%, and the main effective components of the macleaya cordata extract comprise 40-60% of sanguinarine and 10-20% of chelerythrine. The blue-green algae comprise microcystis aeruginosa, anabaena, nematonema, synechocystis, oscillatoria and nostoc. As a plant source in China, the macleaya cordata has great development and utilization values, has the advantages of wide antibacterial spectrum, no drug resistance, no residue, good safety, wide distribution and the like, and has great development prospects.

The application belongs to the technical field of biocontrol preparation, and particularly relates to a traditional Chinese medicine composition, a biocontrol preparation and application in the field of pearl plant leaf spot nematode disease prevention and treatment. The leaf spot nematode disease is a main disease and pest of pearl plant planting, and there is no effective prevention and treatment method at present. The application provides a traditional Chinese medicine composition, which comprises wolfberry, leigongteng, peppermint, phellodendron, boerhaavia diffusa and chamomile. Water extracts of the above-mentioned medicinal ingredients can effectively reduce the number of nematodes in soil and improve the disease resistance of pearl plants when used for pearl plant irrigation. The research results of the application are helpful for restraining the occurrence of pearl plant leaf spot nematode disease through biological prevention and control means, and provide theoretical guidance for the development of pearl plant green industry.

The invention belongs to the technical field of chemical detection, and particularly relates to a detection method of macleaya cordata alkaloid. The macleaya cordata alkaloid is detected through the three steps of macleaya cordata alkaloid extraction, standard curve drawing and sample determination, and compared with a traditional large instrument detection method, the method has the advantages that the detection mode is simpler and more convenient, and the operation process is simple; the time required by the whole process is less than half an hour; the detection mode is lower in cost, and detection can be completed only by using a small-sized instrument, namely an ultraviolet spectrophotometer. The detection linear range is wide, and the macleaya cordata total alkaloids can be accurately detected.

The invention belongs to the technical field of plant extraction, and provides an extraction method of macleaya cordata alkaloid. The method comprises the following steps: (1) drying macleaya cordata, crushing to obtain coarse powder, putting the coarse powder into a plurality of extraction kettles, inputting a carbon dioxide supercritical fluid and an auxiliary extraction agent into the extraction kettles, and carrying out supercritical extraction on the coarse powder; (2) after supercritical extraction, performing reduced pressure separation on supercritical fluid carrying an extract through at least two stages of separation kettles in sequence to obtain a macleaya cordata extract; the operation pressure of the separation kettle is 2-15 MPa, and the temperature is 25-55 DEG C; and sequentially carrying out molecular distillation purification, concentration and drying on the macleaya cordata extract to obtain a finished product. The extraction method is mild in operation condition, high in production efficiency, high in alkaloid extraction rate, low in energy consumption and small in environmental pollution, and a high-purity product can be obtained through extraction.

The application discloses a benzofuran glycoside compound, a separation and extraction method thereof, a pharmaceutical composition and application, and the compound 1 is separated from a macleaya cordata extract. A benzofuran compound is obtained by separating and purifying a n-butanol part chemical component of a macleaya cordata root. The inhibitory activity of all separated compounds 1 on a target point cyclooxygenase-2 of an inflammatory related disease is tested, the compound 1 has good inhibitory activity on COX-2 enzyme, and the compound 1 has better binding energy with the target point protein. The compound also has good NLRP3 related inhibitory effect, can be used alone or in combination with other drugs to regulate NLRP3 related proteins, is used for treating NLRP3 related mediated diseases and / or diseases, and is used for preparing drugs for preventing or treating the diseases. The compound 1 also has better inhibitory effect on acetylcholinesterase, and can be used for treating diseases such as Alzheimer's disease, myasthenia gravis and Parkinson's disease.

The application discloses Mao-calelloside A and B and a preparation method thereof, and belongs to the technical field of natural product organic synthesis and the technical field of medicines. The application provides Mao-calelloside A and Mao-calelloside B which are novel five-ring enanti-kaurene diterpene compounds and a preparation method thereof. The compound is synthesized for the first time, the synthesis route is novel, the synthesis method can provide an effective means for structural optimization based on ombuoside, and has important research value and application prospect.

The invention discloses a deodorizing bacteriostatic agent based on zeolite and plant extracts and a preparation method of the deodorizing bacteriostatic agent, and relates to the field of deodorizing and bacteriostasis. The deodorizing bacteriostatic agent based on the zeolite and the plant extract is prepared from the following raw materials in parts by weight: 40 to 70 parts of zeolite, 10 to 30 parts of montmorillonite, 2 to 7 parts of metal ion antibacterial compound and 5 to 15 parts of macleaya cordata extract concentrated powder. According to the technical scheme, the zeolite and the montmorillonite are used as base materials, and the metal ion antibacterial compound and the macleaya cordata extract concentrated powder with specific contents are added, so that the prepared odor-removing bacteriostatic agent has excellent odor-removing and bacteriostatic effects, is wide in antibacterial spectrum, and can better play a role in balancing odor-removing and bacteriostatic effects.

The invention discloses a sanguinarine sterilization composition containing a macleaya cordata extract and application of the sanguinarine sterilization composition. The sanguinarine sterilization composition mainly comprises sanguinarine and pydiflumetofen. The two components do not have cross resistance, the two medicaments have obvious synergistic effect after being combined according to a certain ratio, and a common agricultural bactericide dosage form is prepared by adding a proper amount of agricultural bactericide auxiliaries and has higher control effect on fungal diseases of crops. Through combined use of the formula, the dosage can be reduced, the drug resistance of germs to a single agent can be delayed, ecological damage and environmental pollution are effectively reduced, and the yield and quality of crops can be improved; the composition can efficiently prevent and control crop sickle root rot, increases a disease prevention spectrum, and can prevent common crop diseases such as anthracnose, leaf spot, early blight, brown blotch and gray mold at the same time.

The invention belongs to the technical field of plant extraction, and discloses influence of different extraction processes on yield of macleaya cordata extract and application of the macleaya cordata extract in grass carp feed. The invention discloses a macleaya cordata extract preparation method, which comprises: mixing macleaya cordata and an acidic ethanol solution, carrying out reflux extraction, collecting the extraction liquid, and concentrating to obtain the macleaya cordata extract. According to the method disclosed by the invention, the process conditions mainly involved in the extraction process of the macleaya cordata, such as the concentration of ethanol, the material-liquid ratio of acidic ethanol to macleaya cordata powder, the reflux extraction time and the temperature condition during concentration, are investigated. The extraction process of the macleaya cordata is moderately optimized by detecting the content of sanguinarine in the extract, so that the optimal extraction process of the macleaya cordata extract is obtained, and the extraction efficiency of alkaloid (sanguinarine) in the macleaya cordata can be effectively improved by the process.

The invention relates to the field of traditional Chinese veterinary medicine extraction, in particular to a method for extracting macleaya cordata pod alkaloid through ultrasonic-assisted enzymolysis. The macleaya cordata pod alkaloid is extracted by adopting ultrasonic-assisted enzymolysis. According to the method, the extraction rate of the alkaloid in the macleaya cordata pods is relatively high. The method provided by the invention has the advantages of simple required equipment, simplicity and convenience in operation, safety, high extraction rate and easiness in industrial production.

The present invention belongs to the field of pesticide technology and discloses an agricultural composition containing matrine and a Macleaya cordata extract and its application. The mass ratio of matrine to Macleaya cordata extract in the agricultural composition provided by the present invention is 2:8 or 4:6 to 6:4. The agricultural composition has a good inhibitory effect on Pseudomonas syringae pv. cucumber angular leaf spot, the pathogen of cucumber bacterial angular leaf spot. Within the mass ratio range provided by the present invention, the agricultural composition has a synergistic effect on the inhibition of Pseudomonas syringae pv. cucumber angular leaf spot. The agricultural composition provided by the present invention has a good preventive effect on cucumber bacterial angular leaf spot, with a preventive and control effect of 79.2 to 89.5%. The present invention provides a highly efficient, low-toxic, and low-pollution biopesticide for the prevention and control of cucumber bacterial angular leaf spot.

The invention belongs to the technical field of animal feed, and particularly relates to a natural plant feed raw material capable of replacing aureomycin and a preparation method of the natural plant feed raw material. The traditional Chinese medicine composition is prepared from the following natural plant raw materials in parts by weight: 15 to 25 parts of radix astragali seu hedysari, 10 to 20 parts of fructus crataegi, 10 to 18 parts of fructus hippophae, 8 to 15 parts of fructus schisandrae chinensis, 8 to 15 parts of herba portulacae, 6 to 12 parts of flos lonicerae, 10 to 18 parts of radix codonopsis and 6 to 12 parts of macleaya cordata. The natural plant feed raw materials are from pure traditional Chinese medicines / natural plants, are free of antibiotics and chemical additives, and are used for replacing aureomycin to serve as feed additives or premix for fattening monogastric / ruminants such as pigs, cattle, sheep and horses. The natural plant feed raw materials are prepared by adopting an integrated innovative process of directional enzymolysis pretreatment, ultrasonic-microwave synergistic extraction, green entrainer modified supercritical COextraction, lipidosome and nano-composite embedding, directional enrichment and efficient extraction of active ingredients and targeted release of intestinal tracts are realized, and the extraction rate of the active ingredients is improved compared with that of a traditional process.

The invention discloses a feed additive composition for relieving microcystin toxicity and preparation and application thereof.The composition is composed of eucommia ulmoides extract, astragalus membranaceus extract, radix bupleuri extract and macleaya cordata extract.The plant extract composition is added into feed, so that the growth performance of aquatic organisms can be promoted, the oxidation resistance and immunity are enhanced, and the microcystin toxicity can be relieved. The survival rate under the stress of the microcystic toxins is improved. The raw materials are non-medication parts of Chinese herbal medicines, and are low in price, ecological, environment-friendly, healthy and pollution-free.

The invention discloses a method for preparing briquette fuel by utilizing macleaya cordata extraction residues and sludge, which comprises the following steps: mixing the macleaya cordata extraction residues and the sludge, and stirring to obtain microbubble sludge; the microbubble sludge is dried, and semi-dried sludge is obtained; and mixing the macleaya cordata extraction residues with the semi-dried sludge, and carrying out compression molding to obtain the briquette fuel. Compared with a conventional sludge briquette fuel preparation method, the method has the advantages that the macleaya cordata extraction residues and the sludge are used as raw materials, and the briquette fuel which is high in energy density and low in pollution gas and particulate matter yield can be prepared through stirring, drying treatment and compression molding; meanwhile, the method also has the advantages of simple process, convenience in operation, low cost, high preparation efficiency, low energy consumption, no secondary pollution and the like, is suitable for large-scale preparation, is convenient for industrial application, is favorable for realizing reduction and recycling of macleaya cordata extraction residues and sludge, and has high benefits and good application prospects.

The invention discloses a Macleaya cordata dwarfing and stem strengthening cultivation method, and belongs to the technical field of dwarfing cultivation, the method comprises the following steps: S1, soil pretreatment: using pine needles to carry out soil decomposition pretreatment to obtain a decomposed substance; s2, soil preparation and furrowing: mixing the decomposed substances with field soil, and performing deep ploughing, leveling and furrowing; s3, sowing and first chemical control: after sowing, spraying a composite dwarfing agent on leaf surfaces for the first time in a seedling stage of macleaya cordata; s4, pinching: pinching when the plant grows to the height of 50cm; s5, field management and harvesting: spraying the compound dwarfing agent on leaf surfaces for the second time in a squaring stage of macleaya cordata, and performing conventional management until harvesting; the composite dwarfing agent comprises chlormequat chloride, a root growth promoting agent, ethephon, a biological stimulant, trace elements and an auxiliary agent, and a solvent is water. According to the method, an ideal plant type control effect is achieved, the economic yield and the medicinal component content are remarkably increased, and the method has the advantages that the dwarfing effect is stable, the plant robustness is high, and the yield and quality are synergistically improved.

The invention belongs to the technical field of pesticides, and particularly relates to a macleaya cordata alkaloid suspending agent for preventing and treating tea geometrid of tea trees and a preparation method of the macleaya cordata alkaloid suspending agent. The macleaya cordata alkaloid suspending agent for preventing and treating tea geometrid of tea trees comprises the following components in percentage by weight: 5%-50% of macleaya cordata alkaloid, 1%-10% of tea saponin, 1%-10% of a dispersing agent, 1%-10% of an anti-freezing agent, 0.05%-2% of a thickening agent, 0.05%-0.5% of a defoaming agent, 0.01%-0.1% of a preservative and the balance of deionized water. After the macleaya cordata alkaloid and the tea saponin are mixed, the synergistic effect is obvious, alkaloid particles in the suspending agent are fine, can rapidly permeate into plant tissues to play a lasting pesticide effect, and have a remarkable insecticidal effect on tea geometrid, and the tea geometrid is not prone to generating drug resistance to the suspending agent. The pesticide is a botanical pesticide, no dust is generated in the application process, the pollution of the pesticide to the environment is small, the required materials are easy to obtain, and the industrial production cost is low.