8 results about "Antipruritic" patented technology

The invention belongs to the field of biological pharmacy, and discloses a GPCR-based ultramicro drug screening method and application thereof in screening of antipruritic traditional Chinese medicines. According to the invention, an Echo ultrasonic pipetting system is combined with a GPCR function experiment (beta-arrest recruitment) to establish the ultramicro screening method for screening the GPCR ligand. The Echo 550 system utilizes ultrasonic waves to beat liquid into 2.5 nL liquid drops and then transfer the liquid drops into a 384 or 1536 pore plate, rapid and accurate sample adding of at least 2.5 nL (1 / 400 mu L) can be achieved, ultra-micro screening and high-throughput screening can be achieved at the same time, and the method is particularly suitable for screening of itching relieving drugs.

The present invention discloses a Li medicine for anti - inflammation and anti - allergy and its preparation method. The process includes: on the basis of the original Li medicine prescription, adding Yajiasong pollen newly, and developing a Li medicine for anti - inflammation and anti - allergy. Anti - inflammation, anti - allergy and antipruritic experiments are carried out on this Li medicine. The results fully prove that: Yajiasong pollen, the traditional Li medicine for anti - inflammation and anti - allergy, and the Li medicine compounded by Yajiasong pollen and the traditional Li medicine all have the effects of anti - allergy, anti - inflammation and antipruritic. In addition, the effect of the Li medicine for anti - inflammation and anti - allergy is superior to that of Yajiasong pollen and the traditional Li medicine prescription used alone, thus broadening the development space and approach for protecting and inheriting the effective prescriptions of Li medicine.

The invention belongs to the field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine external preparation for dispelling wind and arresting itching and application thereof. The traditional Chinese medicine external preparation is prepared from the following raw materials: 10-30 parts of fried fructus xanthii, 10-30 parts of fructus kochiae, 10-30 parts of rhizoma chuanxiong, 10-30 parts of flos carthami and 5-15 parts of solanum lyratum thunb. The raw materials are subjected to process extraction and refining to obtain the traditional Chinese medicine external preparation. A plurality of processes are researched, and research results show that the itching relieving and detumescence effects of the transdermal drug delivery preparation are obviously superior to those of original oral granules, and the effect is better than that of dermatitis treatment cream sold in the market. According to the traditional Chinese medicine external preparation disclosed by the invention, the anti-inflammatory, detumescence and itching-relieving drug effects are improved, oral administration is changed into external administration, the administration is more direct, the safety is higher, the drug effects are better, the crude drug amount is smaller, and the cost is lower.

This invention provides a method for preparing a thermosensitive gel for the prevention and treatment of nasal diseases and its application. By weight and volume percentage, it comprises recombinant human type III collagen, mussel adhesive protein, an anti-allergy agent, traditional Chinese medicine extracts, thermosensitive materials, and a sodium pyruvate-cocamidopropyl betaine ion-pair complex. This invention, by pre-forming the ion-pair complex, simultaneously solves the technical problems of existing nasal gels, such as poor anti-dilution ability, short adhesion time, and easy inactivation of active ingredients. The product is liquid below 30°C and can be sprayed for complete nasal coverage. At body temperature, it transforms into a gel within 2 minutes for long-lasting adhesion, exhibiting rapid anti-inflammatory, nasal patency-clearing, antipruritic, and mucosal repair effects. It is suitable for the prevention and treatment of allergic rhinitis and sinusitis, as well as nasal wound care, with significantly better efficacy than similar commercially available products.

The present invention belongs to the field of Chinese medicine preparations, and in particular to a Chinese medicine external preparation for dispelling wind and relieving itching and its application. The Chinese medicine external preparation is composed of the following raw materials: 10-30 parts of stir-fried Xanthium sibiricum, 10-30 parts of Kochia scoparia, 10-30 parts of Chuanxiong, 10-30 parts of Carthamus tinctorius, and 5-15 parts of Sophora flavescens, and the above raw materials are extracted and refined by process to obtain the Chinese medicine external preparation. The present invention has studied a variety of processes, and the results of the study show that the antipruritic and detumescent effects of the transdermal drug preparation obtained by the present invention are significantly better than the original oral granules, and are better than the commercially available Piyanping cream. The Chinese medicine external preparation of the present invention not only improves the anti-inflammatory, detumescent, and antipruritic drug effects, but also changes oral administration to external administration, and the administration is more direct, the safety is higher, the drug effect is better, the amount of crude drugs is less, and the cost is lower.

This invention discloses a highly efficient rubbing device for pigs, comprising a rubbing part, which includes several toothed plates fixedly sleeved on a column. All the toothed plates overlap and are arranged close together in the vertical direction, with the tips of adjacent plates staggered. Several through holes are provided on the toothed plates, with the through holes on adjacent plates also staggered. An antipruritic liquid supply pipe is provided above the rubbing part, with the outlet of the antipruritic liquid supply pipe located directly above the top toothed plate. The rubbing device provided by this invention not only effectively prevents pigs from intermittently and frequently rubbing themselves, but also significantly improves the efficiency of rubbing and relieving itching, and significantly extends the service life of the device. It can achieve precise rubbing and relieving of itching in specific areas of the pig, improving the comfort and targeting of the pig during the rubbing process.

The invention discloses a traditional Chinese medicine composition for treating haemorrhoids as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition for treating haemorrhoids is prepared from 16 to 24 parts of radix sophorae flavescentis, 16 to 24 parts of cortex phellodendri, 8 to 12 parts of radix scutellariae, 12 to 18 parts of radix angelicae sinensis, 12 to 18 parts of rhizoma chuanxiong, 24 to 36 parts of herba taraxaci, 24 to 36 parts of herba portulacae, 16 to 24 parts of radix sanguisorbae, 8 to 12 parts of radix saposhnikoviae, 8 to 12 parts of pericarpium zanthoxyli, 8 to 12 parts of liquorice root, 12 to 18 parts of herba schizonepetae, 16 to 24 parts of rhizoma polygoni cuspidati, 8 to 12 parts of dried alum, 8 to 12 parts of mirabilite, 4.8 to 7.2 parts of borneol and 8 to 12 parts of flos carthami. The traditional Chinese medicine composition disclosed by the invention has the effects of clearing heat and drying dampness, promoting blood circulation to subdue swelling, relieving pain and itching and astringing to stop bleeding. The four medicines of polygonum cuspidatum, borneol, fineleaf schizonepeta herb and szechuan lovage rhizome are linked, and the borneol promotes the permeation of fineleaf schizonepeta herb volatile oil and szechuan lovage rhizome ferulic acid at the same time, so that triple synergy of transdermal, blood activating and itching relieving is formed.

The invention discloses a preparation method of an abelmoschus manihot plant extraction skin cleaning medicated bath bag, and relates to the technical field of traditional Chinese medicine preparations. Comprising the following steps: (1) raw material compatibility and pretreatment: taking 10-25 parts by mass of abelmoschus manihot, 5-15 parts by mass of abelmoschus manihot flowers, 5-15 parts by mass of processed pinellia ternate, 5-15 parts by mass of rheum officinale, 5-15 parts by mass of cortex lycii radicis, 10-20 parts by mass of dandelion, 5-15 parts by mass of cocklebur fruit, 5-15 parts by mass of folium artemisiae argyi, 10-20 parts by mass of senecio scandens, 3-10 parts by mass of nidus vespae, 5-15 parts by mass of saponin, 5-15 parts by mass of cortex dictamni and 1-5 parts by mass of borneol; all plant medicinal materials except borneol are cleaned and dried at the low temperature of 50-65 DEG C till the water content is lower than 8%. By means of the ultra-micro wall breaking and dynamic counter-current extraction combined technology, multiple active ingredients such as abelmoschus manihot total flavonoids, rhubarb anthraquinone and saponin are extracted to the maximum extent, the abelmoschus manihot total flavonoids, the rhubarb anthraquinone and the saponin synergistically play the anti-inflammatory, anti-allergic, antibacterial and itching-relieving effects, and the health care effect is achieved. The traditional Chinese medicine has effects on various skin diseases such as psoriasis and eczema