20 results about "Anti allergy" patented technology

This invention belongs to the field of anti-allergy functional food technology, specifically relating to an anti-allergy composition containing inactivated Akkermansia myxophilus. Existing anti-allergy drugs have side effects. The composition of this invention contains inactivated Akkermansia myxophilus, quercetin, vitamin C, and zinc. This invention can improve allergic rhinitis, alleviate eczema symptoms, and improve allergic constitution by regulating immune balance and inhibiting histamine release. The composition of this invention is stable at room temperature and can be formulated into powder or chewable tablets.

Disclosed is a pharmaceutical composition in dry powder form for intranasal administration, comprising an anti-anaphylactic adrenergic receptor agonist in the form of dry powder for intranasal administration, the composition comprising solid particles of the active agent in combination with at least one functional additive, and solid particles of an inert carrier.

Pharmaceutical composition comprising a Pickering oil-in-water emulsion containing an aqueous phase, a vegetable oil phase, and an organomodified phyllosilicate, particularly for its use in increasing TAFA4 production, and possibly for increasing serotonin production, for its use as a cutaneous anti-inflammatory agent and / or wound-healing agent and / or as a cutaneous anti-allergy agent. Figure to be published with the abstract: none.

This invention provides a method for preparing a thermosensitive gel for the prevention and treatment of nasal diseases and its application. By weight and volume percentage, it comprises recombinant human type III collagen, mussel adhesive protein, an anti-allergy agent, traditional Chinese medicine extracts, thermosensitive materials, and a sodium pyruvate-cocamidopropyl betaine ion-pair complex. This invention, by pre-forming the ion-pair complex, simultaneously solves the technical problems of existing nasal gels, such as poor anti-dilution ability, short adhesion time, and easy inactivation of active ingredients. The product is liquid below 30°C and can be sprayed for complete nasal coverage. At body temperature, it transforms into a gel within 2 minutes for long-lasting adhesion, exhibiting rapid anti-inflammatory, nasal patency-clearing, antipruritic, and mucosal repair effects. It is suitable for the prevention and treatment of allergic rhinitis and sinusitis, as well as nasal wound care, with significantly better efficacy than similar commercially available products.

The use of AKR1C3 enzyme-activated DNA alkylating agent prodrug compounds containing aziridine structures, as well as their salts, esters, solvates, and isotopic isomers, in combination with anti-allergy drugs / nonsteroidal analgesics for the treatment of cancer and tumor patients; and the use of AKR1C3 enzyme-activated DNA alkylating agent prodrug compounds containing aziridine structures, as well as their salts, esters, solvates, and isotopic isomers, in combination with anti-allergy drugs / nonsteroidal analgesics in the preparation of drugs for the treatment of cancer and tumors.

A pharmaceutical composition includes a Pickering emulsion O / W containing an aqueous phase, a vegetal oil phase and an organically modified phyllosilicate, in particular for use to increase the production of TAFA4, and possibly to increase the production of serotonin, for use as an anti-inflammatory and / or anti-allergy agent.

The application discloses a preparation method of a magnolia extract and belongs to the technical field of traditional Chinese medicine extraction. The method comprises the following steps: (1) after the magnolia is crushed and soaked, a solvent is added, and then the magnolia is heated for extraction in a vacuum environment; after cooling, centrifugal filtration is performed to obtain a precipitate A and an oil-water mixture B; (2) the oil-water mixture B is separated into an oil phase and an aqueous phase; the obtained aqueous phase is mixed with the precipitate A to obtain a mixture C; the obtained oil phase is dried and filtered to obtain an oil phase extract P-1; (3) a solvent is added to the mixture C, and then the mixture C is heated for extraction in a vacuum environment; after cooling, filtration is performed to obtain a precipitate D and a mixture E; (4) an organic solvent is added to the mixture E, and then the mixture E is separated into an oil phase and an aqueous phase; the obtained oil phase is dried and filtered to obtain the magnolia extract P-2. The preparation method has the advantages of high extraction efficiency, good retention of volatile components, low energy consumption and environmental friendliness; the prepared magnolia extract has high content of lignan components, stable quality, and is suitable for preparing medicines or health products for resisting inflammation, resisting allergy and treating nasal diseases.

The present application relates to the field of cosmetic technology, and more particularly to a kind of acne, anti-allergic skin care product composition and preparation method thereof.The present application uses emollient, humectant, emulsifier, thickening agent, bamboo leaf pricklyash extract, saffron extract, purple magnolia extract, gentian extract, salicylic acid and water to prepare skin care product, and the skin care product has excellent acne and anti-allergic properties;After 7 days of using the skin care product of the present application, the improvement rate of skin acne lesion red area reaches 20.34%, and the improvement rate of acne quantity reaches 40.66%.

This invention relates to a traditional Chinese medicine composition and its preparation, comprising the following raw materials in parts by weight: rhubarb 18-30 parts, gardenia 18-30 parts, chuanxiong rhizome 9-16 parts, cinnamon twig 9-16 parts, safflower 1-10 parts, and frankincense 1-10 parts. This invention relates to the technical field of external preparations of traditional Chinese medicine. In the traditional Chinese medicine composition of this invention, rhubarb: clears heat and detoxifies, drains heat and promotes bowel movement, cools blood and detoxifies, removes blood stasis and unblocks meridians, has anti-inflammatory effects, and immunomodulatory effects; gardenia: clears heat and promotes diuresis, cools blood and detoxifies; chuanxiong rhizome: invigorates blood and promotes qi circulation, dispels wind and relieves pain; safflower: invigorates blood and unblocks meridians, disperses blood stasis and relieves pain; cinnamon twig: induces sweating and relieves muscle tension, warms and unblocks meridians, promotes qi circulation, calms the bladder and lowers qi, relieves joint pain, has antibacterial effects, anti-inflammatory and anti-allergic effects, dilates blood vessels, and promotes sweating. Frankincense: promotes blood circulation, relieves pain, reduces swelling and promotes tissue regeneration; when used together, these herbs target the core pathogenesis of traumatic swelling and pain (blood stasis), gouty arthritis (damp-heat stagnation), and skin infections (heat toxicity), achieving the treatment of three types of diseases with one ointment, filling a market gap.

This invention belongs to the field of biomedical technology, specifically relating to a composition for relieving respiratory discomfort, its applications, and products. The invention provides a composition for relieving respiratory discomfort, comprising a prebiotic and a compound probiotic composition; the prebiotic is fructooligosaccharide and polydextrose; the compound probiotic composition consists of *Bifidobacterium longum* subsp. *longum* BB536, *Bifidobacterium breve* M-16V, and *Bifidobacterium longum* subsp. *infant* M63. The composition provided by this invention can relieve airway inflammation, regulate the body's microecological balance, regulate immunity, significantly downregulate IgE, and has significant anti-inflammatory and anti-allergic effects. This composition can effectively treat infectious or allergic respiratory diseases, relieve cough, downregulate the content of pro-inflammatory factors, and reduce inflammation. This invention can effectively improve nasal allergy symptoms and reduce the frequency of nasal allergy recurrence. The composition of this invention has good application prospects in relieving respiratory discomfort.

An external anti-itch and anti-allergic drug after biting of biting midges and a preparation method thereof, relate to the technical field of medicine. The drug comprises: loratadine hydrochloride 0.1%-0.3%, 5%-8% lapis alumen, menthol 0.5%-1%, camphor 0.3%-0.5%, carvacrol 0.2%-0.5%, lemon eucalyptus oil 0.3%-0.6%, glycerol 3%-5%, panthenol 2%-4%, ceramide 0.1%-0.2%, vaseline 10%-15%, lanolin 5%-8%, deionized water and an appropriate amount of preservative. The preparation method comprises oil phase preparation, water phase preparation, high-speed emulsification and low-temperature mixing. Through the synergistic effect of anti-histamine components and physical anti-itch components, the multiple effects of rapid anti-itch, swelling, anti-allergy and skin barrier repair are realized, the pH value is close to the physiological environment of the skin, it is mild and non-irritating, and it is especially suitable for children, pregnant women and sensitive skin groups.

This invention belongs to the field of biomedical technology and provides a mussel adhesive protein and azelastine hydrochloride nasal thermosensitive gel, its preparation and application. The mussel adhesive protein and azelastine hydrochloride nasal thermosensitive gel includes an active ingredient and pharmaceutically acceptable excipients. The active ingredient is recombinant mussel adhesive protein mefp-5 subtype and azelastine hydrochloride. The excipients include a thermosensitive polymer, which is mixed with the active ingredient to form a thermosensitive gel system. This invention solves the technical problem that existing single-drug formulations cannot simultaneously provide rapid symptom relief and long-term mucosal barrier repair for allergic rhinitis by combining recombinant mussel adhesive protein mefp-5 subtype with mucosal repair function with azelastine hydrochloride, which has rapid anti-allergic effects. Pharmacodynamic studies have confirmed that the two active ingredients exhibit a significant synergistic effect (CDI < 0.7) in improving allergy symptoms, inhibiting inflammatory responses, and repairing the mucosal barrier.

This utility model discloses a dotted barrier-type anti-allergy bamboo mat, including a bamboo mat body comprising several bamboo strips. Each bamboo strip has raised dots and ventilation holes, spaced apart. Ventilation seams are formed between the bamboo strips. A flexible edging is provided around the bamboo mat body, with a storage component on one side of the flexible edging and a fixing component on the lower surface of the flexible edging. A woven rope is connected between the bamboo strips. This utility model, through the design of raised dots, reduces the contact area between the skin and the bamboo mat, reducing friction and sweat accumulation. Simultaneously, the gaps between the raised dots form efficient ventilation channels, promoting air convection, accelerating sweat evaporation, effectively relieving stuffiness, and improving contact comfort. Furthermore, the raised dot structure makes it difficult for allergens to adhere and accumulate. The barrier layer can actively kill or inhibit bacteria, mites, and other microorganisms, reducing the growth of allergens at the source and providing a safe and healthy sleep environment for people with allergies.

The utility model provides a kind of nursing instrument, it is related to pet supplies technical field, the nursing instrument includes atomization bin subassembly and main component, atomization bin subassembly includes liquid bin and the atomization piece subassembly being set in liquid bin, atomization piece subassembly is connected with first wiring assembly, and first wiring assembly is set on liquid bin;Main component includes shell and the electric control component being set in shell, electric control component is connected with second wiring assembly, and second wiring assembly is set on shell;Liquid bin is detachably set on shell, to make first wiring assembly and second wiring assembly be connected;The utility model is cooperated by atomization bin subassembly and main component, not only greatly improves the efficiency and effect of pet nursing, and significantly enhances the convenience of equipment use, with good atomization effect simultaneously, it is applicable to pet skin and hair cleaning, ear cleaning, oral cleaning, environmental deodorization, cat hair anti-allergy and pet stress relief and a variety of scenes, such as wide range of application.

This utility model relates to the field of medical device technology and discloses a plastic anti-allergy indwelling needle patch. Its features include a patch (1) and an indwelling needle tube (3) disposed inside the patch (1). The structure of the indwelling needle tube (3) conforms to the shape of a commonly used indwelling needle. A fixing cotton (5) is disposed inside the indwelling needle tube (3) to compress and fix the indwelling needle. An opening is provided on one side of the indwelling needle tube (3) on the patch, and a fixing plate (4) is provided at the opening. The fixing plate (4) holds the indwelling needle in place and is fixed to the patient's skin using fixing patches on both sides to prevent the indwelling needle from falling off. This avoids patient discomfort caused by prolonged use of the patch 1 and improves patient comfort when using the indwelling needle patch.

This invention discloses a method and system for predicting probiotic ratios based on multi-source data features, belonging to the field of microbial technology. The specific steps of the method are as follows: First, select strains to obtain multi-dimensional data such as genomes, and construct a four-dimensional dataset after standardization; then, mine allergy biomarkers to form a high-sensitivity set; next, construct an efficacy ratio model and output strain rankings; then, verify and screen highly active proprietary strains and culture and preserve them; finally, develop compositions, determine the optimal ratio, use encapsulation technology, and complete the full-chain safety and efficacy verification through multi-stage evaluation. This invention promotes the data-driven evaluation of probiotic efficacy by integrating multi-dimensional data resources, mining allergy biomarkers, constructing models to accurately screen highly active strains, and establishing a strain verification system, optimizing culture media and fermentation processes, scientifically compounding proprietary strains and prebiotics, and completing the full-chain verification of compositions, providing complete technical support for the development of anti-allergy probiotic products.

This invention relates to the field of traditional Chinese medicine antibacterial liquid technology, and particularly to a traditional Chinese medicine antibacterial liquid for nasal use, made from the following raw materials: Xanthium sibiricum, Centipeda minima, Magnolia biondii, Asarum heterotropoides, Acorus tatarinowii, Akebia trifoliata, Atractylodes lancea, Indigo naturalis, Mentha haplocalyx, and polyhexamethylene biguanide. This invention combines nine traditional Chinese medicines—Xanthium sibiricum, Centipeda minima, Magnolia biondii, Asarum heterotropoides, Acorus tatarinowii, Akebia trifoliata, Atractylodes lancea, Indigo naturalis, and Mentha haplocalyx—with polyhexamethylene biguanide. The traditional Chinese medicine components are an improvement on the ancient formula of Xanthium sibiricum powder, synergistically exerting the effects of clearing the lungs and nasal passages, dispelling wind and cold, and anti-inflammatory and anti-allergic properties. Polyhexamethylene biguanide provides broad-spectrum antibacterial efficacy. By changing the traditional oral dosage form to a nasal drop, the liquid acts directly on the nasal mucosa lesion site, avoiding the first-pass effect of the liver and the metabolic burden on the kidneys associated with oral medications, significantly improving drug safety. Skin irritation, eye irritation, and allergy tests all showed no irritation or sensitization.