136 results about "Anti allergy" patented technology

The invention discloses a lactobacillus rhamnosus strain with antiallergic activity and a preparation method thereof, the strain is lactobacillus rhamnosus Lrn-PG-06, the classification name of the strain is Lactobacillus rhamnosus, the preservation number is CGMCC (China General Microbiological Culture Collection Center) No.3077, the preservation time is March 21, 2024, the preservation unit is China General Microbiological Culture Collection Center, the preservation number is CGMCC No.3077, and the preservation number is CGMCC No.3077. The address is No.3, Yard 1, Beichen West Road, Chaoyang District, Beijing. The lactobacillus rhamnosus Lrn-PG-06 strain is high in acid resistance, alkali resistance and cholate resistance, high in simulated gastrointestinal fluid resistance and high in oxidation resistance, has the advantage of resisting allergy, and solves the problems that at present, allergic diseases are mainly treated by drugs or are prevented from being in contact with allergens in the environment and food, but due to the fact that the drugs are large in toxic and side effects, the allergens cannot be in contact with the allergens in the environment and food. And allergens causing anaphylaxis are difficult to determine, so that allergic diseases are difficult to treat or prevent.

The invention belongs to the technical field of preparation of probiotics, and provides a bacterial strain with anti-allergic and immunity-improving effects and application of the bacterial strain. According to the method, a three-layer physical self-assembly structure is adopted, and polysaccharide-polyphenol layer-by-layer self-assembly coating treatment, lipid insertion layer treatment and calcium ion crosslinking protection coating treatment are sequentially carried out. And mannan oligosaccharide MOS and / or galactooligosaccharide GOS are / is mixed in the chitosan layer in a ratio of 0.05-0.15% w / v, and the surface sugar ligand density reaches 4-8 [mu] g per 10 CFU. The coating is constructed under the condition that the pH value is 5.4-5.8; the thickness of the lipid layer is 20-80 nm when the pH value is 5.6-6.2; the cross-linked layer is treated at the pH of 6.0-6.5, so that the gastric acid environment is stable for 2 hours, and the gastric acid is controllably released in intestinal juice for 2-4 hours. The prepared strain has the total thickness of 220-900 nm, the outermost layer coverage rate is larger than or equal to 85%, the gastric juice survival rate is remarkably improved, the strain can be prepared into an oral preparation to be used for preventing and relieving allergic diseases, the viable count of each dose is 1 * 10 <-1 > * 10 <-1 > CFU, and the process is mild and suitable for industrial production.

The invention belongs to the technical field of food engineering, and particularly relates to an anti-allergic special medical infant milk protein partial hydrolysis formula food composition, a preparation method and application. According to the infant milk protein partial hydrolysis formula food composition for the special medical purpose, the mass ratio of the 2 '-fucosyllactose to the lactobacillus acidophilus NCFM to the bifidobacterium animalis Bi-07 is (150-200): (5-10): (2-8). The partially hydrolyzed formula food composition provided by the invention can prevent respiratory tract infection and maintain the natural defense capability of children; the infant health is promoted; the method helps infants to establish healthy intestinal microflora, which is crucial to immune system and cognitive development.

The invention relates to a traditional Chinese medicine composition for preventing and treating liver rupture syndrome of broiler breeders and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following raw material medicines in parts by mass: 50-200 parts of silybum marianum, 50-200 parts of schisandra chinensis, 50-200 parts of gentiana macrophylla, 50-200 parts of andrographis paniculata, 50-200 parts of radix paeoniae alba, 50-200 parts of oldenlandia diffusa, 50-200 parts of folium isatidis and 50-200 parts of patrinia. The traditional Chinese medicine composition has the effects of resisting endotoxin, inflammation, allergy and liver injury and the like, and effectively prevents and treats the liver rupture syndrome of the broiler breeders.

The invention belongs to the technical field of traditional Chinese medicines, mainly relates to a preparation method of herbal ointment, and in particular relates to a preparation method and application of specific endowment herbal ointment. The formula disclosed by the invention comprises herbal fermentation liquor, herbal enzymatic hydrolysate and herbal extracting liquor, wherein the herbal fermentation liquor is obtained by fermenting mint, purple perilla, chrysanthemum, radix angelicae and pericarpium citri reticulatae through probiotics and then filtering; the herbal enzymatic hydrolysate is obtained by performing enzymolysis and extraction on semen armeniacae amarae and poria cocos; the herbal extracting solution is obtained by extracting smoked plum, lily and liquorice with water. The herbal ointment prepared by the invention has the effects of resisting allergy, relieving itching, diminishing swelling and relieving eczema and rhinitis.

The invention relates to the field of anti-allergic compositions, and discloses an immunoregulation anti-allergic compound powder based on non-active yeast and probiotics, and the immunoregulation anti-allergic compound powder comprises the following components in parts by mass: 15-30 parts of non-active yeast powder, 10-25 parts of a probiotic composition, 40-55 parts of a prebiotic composition, 4-6 parts of fucoidin, 0.5-1.5 parts of N-acetylneuraminic acid, and 5-10 parts of an auxiliary material; wherein the prebiotic composition is prepared from resistant dextrin, stachyose, fructo-oligosaccharide and galactooligosaccharide; the auxiliary materials comprise at least two of anhydrous dextrose, acerola cherry powder, elderberry powder, sorbitol and yeast beta-glucan. Through the coupling design of low-temperature mixing and a step-by-step embedding process, the mobility of the powder is maintained, and meanwhile, the activity of thermosensitive components is kept. Compared with a conventional high-temperature mixing or disordered adding process, the problems of component damage and function loss caused by a heat effect or mechanical shearing are solved.

We provide fibers using microcapsule technology. [Solution] The fiber 5 comprises a mixture of phase-change microcapsules 1, functional microcapsules 2, and a substrate. The mixture of phase-change microcapsules, functional microcapsules, and substrate comprises the phase-change microcapsules comprising a phase-change core material and a phase-change wall material coated on the phase-change core material. The phase-change core material comprises any one or any combination of organic PCM material, inorganic PCM material, or bio-based PCM material. The functional microcapsules comprise a functional core material and a functional wall material coated on the functional core material. The functional core material comprises any one or any combination of anti-mite aid, anti-fungal aid, antibacterial and anti-fungal aid, deodorizing aid, moisturizing aid, or anti-allergy aid. The fiber integrates multiple functions, such as cooling sensation, anti-mite, anti-fungal, deodorizing and disinfecting, moisturizing, and anti-allergy. The fiber can meet the needs of use in various environments, satisfy users' demands for diverse textile functions, and improve practicality.

The invention discloses a composition and application thereof, and the composition comprises synephrine or a pharmaceutically acceptable salt thereof, and further comprises naringin, neohesperidin and / or hesperidin. The composition prepared by compounding the synephrine or the pharmaceutically acceptable salt thereof with the naringin, the neohesperidin and / or the hesperidin has the effects of relieving, repairing, resisting wrinkles, easing pain, relieving itching or resisting allergy when being used as a functional component of a skin care product; when being used as a functional component of a scalp care product, the shampoo has the effects of removing dandruff, removing oil, relieving itching or preventing alopecia.

The invention discloses a signal acquisition system of a self-adaptive film electrode patch for heart diseases, and relates to the technical field of medical instruments, the signal acquisition system comprises a flexible substrate, a nano electrode wire, an electrode patch and a circuit module; a bonding layer is arranged on the bottom surface of the flexible substrate, an anti-allergic medicine is distributed in the bonding layer, and the flexible substrate is used for being attached to the skin surface through the bonding layer; the plurality of nano electrode wires are distributed on the bonding layer of the flexible substrate, one ends of the plurality of nano electrode wires are respectively arranged at the detection points, the other ends of the plurality of electrode wires are connected with the circuit module, and the circuit module is used for outputting electric signals collected by the electrode paste; the electrode patch comprises a flexible conductive base layer and a contact layer, a printed circuit is arranged on one side of the flexible conductive base layer, the contact layer is attached to the printed circuit, the other side of the flexible conductive base layer is used for being bonded to a flexible substrate and located at a detection point, and the flexible conductive base layer is conducted with the nano electrode wire; the collection system is simple to operate, and solves the problems that an existing lead wire is easy to wind, the surgical field is affected, and skin allergy is caused by patch. The method has high use value and popularization value.

This invention belongs to the field of anti-allergy functional food technology, specifically relating to an anti-allergy composition containing inactivated Akkermansia myxophilus. Existing anti-allergy drugs have side effects. The composition of this invention contains inactivated Akkermansia myxophilus, quercetin, vitamin C, and zinc. This invention can improve allergic rhinitis, alleviate eczema symptoms, and improve allergic constitution by regulating immune balance and inhibiting histamine release. The composition of this invention is stable at room temperature and can be formulated into powder or chewable tablets.

The invention discloses an oral care composition and application thereof. The oral care composition disclosed by the invention is prepared from guaiazulene, allantoin and dipotassium glycyrrhizinate. According to the oral care composition disclosed by the invention, guaiazulene, allantoin and dipotassium glycyrrhizinate are organically combined, so that gingival bleeding can be effectively relieved, gingival inflammation can be relieved, and uncomfortable symptoms such as red and swollen gingiva and pain can be eliminated; the three components can synergistically promote oral mucosa repair, enhance anti-inflammatory and anti-allergic effects, comprehensively nurse oral health, and can be prepared into various oral care products.

The present application relates to the application of an acidic goat milk oligosaccharide composition in the preparation of an anti-allergy drug or food, the composition comprising 24 acidic sugar chains 24SMAOs, among which, according to the classification of sialic acid structure, 12 Neu5Ac modified sialylation sugar chains, 10 Neu5Gc modified sialylation sugar chains and 2 sialylation sugar chains modified by both Neu5Ac and Neu5Gc, according to the classification of sialic acid connection mode, 11 alpha2,3 connected sialic acid sugar chains, 10 alpha2,6 connected sialic acid sugar chains and 3 sialic acid sugar chains connected by both alpha2,3 and alpha2,6. The composition belongs to a natural anti-allergy substance, has safety and effectiveness, and realizes excellent anti-allergy performance.

A use of extracts of roselle seeds for preparing a composition of antioxidant, anti-inflammation, anti-UVB, anti-allergy, whitening, moisturizing, and anti-wrinkle, wherein the extracts of the roselle seeds comprise lauric, palmitic, linoleic, oleic, or stearic acids; and a method for preparing the extracts of the roselle seeds comprises steps of: steeping of: extracting a weight ratio of the 12:1 to 20:1 roselle seeds and an ethanol solution with a concentration of 75 to 95%; and steeping the roselle seeds in the ethanol solution to obtain a suspension; and extraction of: the suspension being engaged in an extraction of a continuous and rapid oscillation with an ultrasonic energy with a total energy of 200 to 500W, wherein 1 to 3 hours of the oscillation is one cycle, and a total number of 3 to 5 cycles is lasted, in order to obtain roselle seed crude extracts.

The invention provides a topical spray for treating myiasis on livestock wounds and a preparation method thereof, belonging to the technical field of veterinary drug preparations. The topical spray comprises, by volume, an insecticidal active component: 2-4 parts of diazinon; 0.5-1 parts of wormwood oil; 2-3 parts of peppermint oil; a solvent carrier component: 50-70 parts of xylene; 30-50 parts of diesel; and an emulsifier component: 2-8 parts of emulsifier. In the present invention, the diazinon is an organophosphorus insecticide and acaricide, and has a good killing effect on various mites, flies, lice, and ticks; the wormwood oil has the effects of anti-allergy, anti-inflammatory, blood-activating, antibacterial, antiviral, analgesic, immunity-enhancing, and antioxidant; and the peppermint oil has the effects of anti-inflammatory, analgesic, antibacterial, antiviral, and penetration-promoting. The diazinon is used in combination with the wormwood oil and the peppermint oil to enhance the insecticidal effect of the diazinon. Meanwhile, the wormwood oil and the peppermint oil can reduce the irritation of the diazinon to animal skin.

The invention relates to the technical field of microorganisms, in particular to a yeast metagen with an anti-allergic effect as well as a preparation method and application of the yeast metagen. According to the invention, the metabolite is an inactivated saccharomyces boulardii strain and a fermentation metabolite thereof, wherein the preservation number of the saccharomyces boulardii strain is CCTCC (China Center for Type Culture Collection) NO: M 20251803. The metagen can be used for remarkably reducing the total IgE (Immunoglobulin E) level of serum and relieving anaphylactic reaction by adjusting the balance of Th1 / Th2, Th17 and Treg immune cells. Therefore, the metabiotics disclosed by the invention have a wide application prospect in preparation of foods, medicines or health-care products for relieving allergic symptoms.

The invention belongs to the technical field of genetic engineering, and particularly relates to truncated tropomyosin, a nucleic acid molecule and application of the truncated tropomyosin. The truncated tropomyosin is based on an alpha-helical structure of tropomyosin, and is obtained by taking glutamic acid (E26) at the 26th site, glutamine (Q51) at the 51st site or glutamic acid (E73) at the 73rd site as a truncation site. By reasonably designing a truncation site and further replacing the secretion signal peptide, the expression quantity of the protein in a recombinant expression system is remarkably improved, the immunogenicity of the protein is effectively reserved, and the protein can be used for precise diagnosis of allergy and development of anti-allergic vaccines.

The invention provides a traditional Chinese medicine composition for treating male hormone alopecia. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 1.5-3 parts of prepared polygonum multiflorum, 1.5-3 parts of scalded rhizoma drynariae, 0.5-1.5 parts of liquorice tablets, 2.5-3 parts of raw cacumen biotae, 2.5-3 parts of salvia miltiorrhiza, 1.5-3 parts of angelica sinensis and 1-2 parts of ligusticum chuanxiong hort. The traditional Chinese medicine composition is obtained by soaking in cold water for 20-30 minutes, decocting and concentrating. The traditional Chinese medicinal materials capable of activating blood circulation, removing blood stasis, nourishing essence and blood and resisting inflammation and allergy are adopted as raw materials, so that the traditional Chinese medicinal composition has multiple effects of activating blood circulation, improving blood circulation and nourishing hair follicles, and the alopecia is cured from the perspective of permanent cure; the traditional Chinese medicines synergistically exert a curative effect, so that the traditional Chinese medicine can nourish hair, prevent alopecia, diminish inflammation and moisten skin.

The invention relates to the field of medicines, in particular to application of LKB1 / AMPK pathway-based fucoidan in preparation of anti-type I anaphylaxis medicines. The LKB1 / AMPK pathway is activated by the alginate, so that mast cell degranulation is effectively inhibited, mast cell mediated cell anaphylaxis is further effectively inhibited, and the alginate can be used for preparing anti-anaphylaxis related drugs.

The application discloses an anti-nasal allergy gel production optimization method based on data analysis, and particularly relates to the field of resource allocation and production optimization, and is used for solving the problem that the response to regional and seasonal demand changes in the existing anti-allergy gel production process is lagging behind, and the raw material supply constraint and the production line switching cost are difficult to balance. The method collects raw material supply chain data, market sales records and environmental allergen time series data, constructs a unified space-time correlation data basis, predicts the anti-allergy response intensity in the future production cycle by using a recurrent neural network, and forms product dosage form preference weights based on association rule mining. On this basis, combined with the raw material inventory and the delivery cycle constraint, a plurality of executable candidate production schemes are generated, and further, the schemes are selected according to the real-time state of the production line and the switching cost, so as to realize the fine configuration and efficient execution of the anti-nasal allergy gel production process.

To provide a novel Lacticaseibacillus rhamnosus strain.SOLUTION: The present invention relates to a novel Lacticaseibacillus rhamnosus ICL-46 strain and its use for anti-inflammation, anti-allergy, skin soothing, and skin microorganism regulation. According to one embodiment of the strain, since it has effects of anti-inflammation, anti-allergy, skin immunity enhancement, atopic dermatitis improvement, skin soothing, and skin microorganism regulation, it can be variously applied to cosmetics, pharmaceuticals, foods, and the like.SELECTED DRAWING: Figure 1

The invention provides anti-allergic toothpaste containing core-shell structure bioactive glass. The anti-allergic toothpaste comprises the following components in percentage by weight: 15-30% of a friction agent, 10-25% of a humectant, 0.5-2% of an adhesive, 0.1-1% of a sweetening agent, 0.1-0.5% of a preservative, 0.5-2% of essence, 1-20% of core-shell structure bioactive glass and the balance of glycerol. A shell of the core-shell structure bioactive glass is boron-containing boron-series bioactive glass, and an inner core of the core-shell structure bioactive glass is silicon-based bioactive glass. Boron-based bioactive glass and silicon-based bioactive glass with different properties are combined to form a core-shell structure, so that the problem that the activity and degradation resistance of the existing bioactive glass are difficult to balance when the existing bioactive glass is applied to anti-allergic toothpaste is solved, and the anti-allergic effect and storage stability of the toothpaste are improved.

Disclosed is a pharmaceutical composition in dry powder form for intranasal administration, comprising an anti-anaphylactic adrenergic receptor agonist in the form of dry powder for intranasal administration, the composition comprising solid particles of the active agent in combination with at least one functional additive, and solid particles of an inert carrier.

To provide an intestinal disorder controlling agent, an antiallergic agent, an immunopotentiator and an intestinal adhesion improver of lactic acid bacteria, safely ingestible, inexpensively available and excellent in intestinal adhesion improving action of lactic acid bacteria.SOLUTION: The agent of the present invention contains a flower extract. The flower is a flower of Lythraceae, Asteraceae, Fabaceae, Rosaceae or Iridaceae, and is particularly preferably at least one selected from the group consisting of safflower, pomegranate, kudzu, cherry, chrysanthemum, saffron, peach and rose.SELECTED DRAWING: Figure 1

The invention discloses a special cleaning agent used in cooperation with tooth brushing and a preparation method thereof, and belongs to the field of tooth cleaning. The toothpaste is prepared from the following components in an equal amount of deionized water: 8.8.6 to 17.8 percent of a surfactant, 5.3 to 11.1 percent of a sterilizing agent, 2.4 to 9.7 percent of an enzyme preparation, 3.6 to 7.9 percent of an anti-allergic agent, 2.3 to 6.7 percent of a flavoring agent, 1.3 to 5.9 percent of a thickening agent, 14.2 to 28.9 percent of a humectant, 3.7 to 4.8 percent of a radix scutellariae extract, 1.3 to 5.6 percent of a coloring agent, 3.5 to 11.5 percent of essence, 0.2 to 0.9 percent of vitamin, 1.5 to 4.9 percent of a foaming agent and 1.5 to 9.9 percent of an emulsifying agent. The special cleaning agent for tooth brushing and the preparation method thereof have the beneficial effects that the special cleaning agent for tooth brushing and the preparation method thereof are provided.

The invention relates to the technical field of pet skin care products, and particularly discloses a universal skin care nutritional supplement for dogs and cats, capable of removing dampness, relieving itching and resisting allergy and a preparation method of the universal skin care nutritional supplement. The invention relates to a general skin care nutritional supplement for dogs and cats with effects of removing dampness, relieving itching and resisting allergy. The nutritional supplement is prepared from the following raw material components in parts by weight: 10 to 20 parts of a dampness removing component, 15 to 20 parts of a moisturizing component, 28 to 34 parts of an itching-relieving and anti-inflammatory component, 1 to 1.5 parts of vitamins, 20 to 25 parts of seasoning powder and 8 to 12 parts of a filling agent, the dehumidifying component comprises rhizoma atractylodis and poria cocos; the moisturizing component comprises angelica sinensis, sea-buckthorn and fish oil. All the raw materials are scientifically proportioned and have a synergistic effect, the five core effects of dehumidification, itching relieving, allergy resistance, inflammation resistance and moisturizing and repairing are fully covered, and the limitation that an existing product is single in effect is overcome.

The invention discloses an application of a nitrobenzene-containing urea compound in preparation of an anti-allergic reaction drug, and the nitrobenzene-containing urea compound can be applied in preparation of a drug for antagonizing mouse sole swelling and plasma exosmosis caused by C48 / 80. The invention also discloses application of the compound in preparation of drugs for antagonizing mouse sole skin vasodilation and mast cell degranulation caused by C48 / 80. The nitrobenzene-containing urea compound can effectively relieve mouse sole swelling and plasma exosmosis, mouse sole skin vasodilation and mast cell degranulation caused by C48 / 80, reduce serum histamine release and relieve body temperature decline, so that the occurrence of anaphylactoid reaction is inhibited, and the nitrobenzene-containing urea compound can be used for preventing and treating hyperplasia. Therefore, when the nitrobenzene-containing urea compound is used as an anti-drug anaphylaxis preparation, more possible treatment schemes are provided for clinical drug anaphylaxis treatment.

The present invention relates to an aqueous pharmaceutical composition for injection comprising doxylamine or a physiologically acceptable salt thereof wherein the concentration of doxylamine is in the range of from 5 mg / ml to 25 mg / ml, based on the weight of doxylamine free base and based on the total volume of the composition; wherein the pH value of the composition is in the range of 6.0 to 7.0. The pharmaceutical composition disclosed by the invention has the effects and effects of sedation, hypnosis, histamine resistance, choline resistance, allergy resistance and the like.

The application discloses a astragaloside IV-gallic acid combination, a nose temperature-sensitive gel and a preparation method thereof, and belongs to the field of pharmaceutical preparations. The astragaloside IV-gallic acid combination is obtained by the reaction of a hydroxyl group in an astragaloside IV molecule and a carboxyl group in a gallic acid molecule. The astragaloside IV-gallic acid combination has good water solubility, can realize the spatiotemporal co-delivery of the astragaloside IV and the gallic acid, and is convenient for playing the synergistic anti-allergy effect of the two. The astragaloside IV-gallic acid combination is further used to prepare the nose temperature-sensitive gel. The nose temperature-sensitive gel is a free-flowing liquid at room temperature of about 25 DEG C, becomes a solid-like gel after being adsorbed on the nasal mucosa, can prolong the release time of the drug, has good nasal mucosa adhesion, and prolongs the residence time of the drug in the nasal cavity.

The compound preparation is characterized by being prepared from the following components in parts by mass: 11 to 13 parts of cortex acanthopanacis, 9 to 12 parts of herba taxilli, 21 to 23 parts of radix achyranthis bidentatae, 9 to 11 parts of radix paeoniae rubra, 8 to 10 parts of herba lycopi, 20 to 22 parts of radix salviae miltiorrhizae, 11 to 13 parts of semen vaccariae, 5 to 8 parts of spina gleditsiae, 6 to 9 parts of rhizoma chuanxiong, 5 to 7 parts of liquorice root and 20 to 22 parts of radix astragali seu hedysari. The medicines are compatible, are mainly used for tonifying liver and kidney, activating blood and inducing diuresis, are compatible with qi and blood, and are suitable for rheumatic arthralgia and chronic inflammation. Cortex acanthopanacis and herba taxilli expel wind-damp and strengthen muscles and bones, herba lycopi and radix achyranthis bidentatae promote diuresis and descend, and the traditional Chinese medicine is suitable for rheumatism edema and lower limb Radix astragali and radix angelicae sinensis tonify qi and nourish blood, radix salviae miltiorrhizae and rhizoma chuanxiong activate blood and promote qi circulation, and the traditional Chinese medicine is suitable for qi and blood stasis type diseases. The liquorice is used for regulating the medicine property of the whole formula and alleviating the drasticality of the cowherb seeds, the spina gleditsiae and the like, and glycyrrhizic acid contained in the liquorice has an anti-allergic effect and reduces the risk of medicine allergy.

The invention discloses a whey protein source peptide with hyaluronidase inhibitory activity. The whey protein source peptide is characterized in that the sequence of the whey protein source peptide is amino terminal-GGVSLPEW-carboxyl terminal. The peptide has the advantages of no toxicity, no sensitization and the like, has a remarkable inhibition effect on hyaluronidase, and can be used for developing functional foods or medicines with anti-allergic characteristics.