127 results about "Anaphylaxis" patented technology

A method for the treatment or prevention of autoimmune diseases, allergic or atopic disorders, and graft rejection is provided, comprising inducing the death by apoptosis of a subpopulation of T lymphocytes that is capable of causing such diseases, while leaving substantially unaffected the majority of other T lymphocytes. Cell death is achieved by cycle(s) comprising challenging via immunization these T cells with antigenic substance at short time intervals, or by immunization followed by administering interleukin-2 (IL-2) when these T cells are expressing high levels of IL-2 receptor so as to cause these T cells to undergo apoptosis upon re-immunization with the antigenic peptide or protein. These methods are applicable to the treatment of autoimmune diseases such as, for example, multiple sclerosis, uveitis, arthritis, Type I insulin-dependent diabetes, Hashimoto's thyroiditis, Grave's thyroiditis, autoimmune myocarditis, etc., allergic disorders such as hay fever, extrinsic asthma, or insect bite and sting allergies, food and drug allergies, as well as for the treatment or prevention of graft rejection.

Methods for making and using therapeutic formulations of Proteosome-based immunoactive compositions are provided. The immunogenic compositions, which include Proteosomes and liposaccharides, may be used to elicit or enhance a nonspecific innate immune response to, for example, treat or prevent infectious disease. In addition, after activating the innate immune system, immunogenic compositions further containing an antigen may be used to elicit a specific adaptive immune response. Furthermore, provided are compositions capable of altering hyperreactive responses or inflammatory immune responses, such as allergic reactions. Such compositions may be used as a prophylactic, or in various clinical settings to treat or prevent infectious disease (such as parasite, fungal, bacterial or viral infections), or to alter inappropriate inflammatory immune responses (such as allergic reactions or asthma).

The invention relates to the field of biological medicine and specifically relates to a compound for hormonous dermatitis, a preparation, a preparation method and an application thereof. The compound comprises the following components: rose hydrosol, grape seed extract, aloe vera gel, liquorice extracting solution, curcumin, apigenin, oat-beta-glucan, amidogen glucan, water-soluble azone, polylysine, water soluble vitamin E, buxus chinensis, 1,2-glutaraldehyde, compound growth factor, hydroxypropyl-beta-cyclodextrin, EDTA-2Na, collagen, humectants, auxiliary material and natural preservatives. The components in the compound have mild action to skin and are free from irritation; the components are collocated with each other, can prevent inflammation and anaphylaxis caused by hormonous dermatitis on the basis of supplying moisture preservation and can restrain bacteria to infect the damaged skin. The added compound growth factor can promote metabolism and repairing of cells of corium layer, epidermis and especially cuticle and can promote the forming of intercellular substance, so as to repair the damaged skin and achieve the effects of protection and curing.

A dynamic high-pressure microfluidization-enzymolysis method for preparing hypoallergenic beta-lactoglobulin. Beta-lactoglobulin in milk is used as a main raw material, and a novel physical processing means of dynamic high-pressure microfluidization technology is combined with trypsin enzymolysis technology to treat the beta-lactoglobulin, so as to obtain the hypoallergenic beta- milk globulin product. The hypoallergenic beta-lactoglobulin prepared by the method has good functionality; and the method can effectively reduce or eliminate anaphylaxis of beta-lactoglobulin. The invention is highly safe and without side effect.

The invention relates to the field of traditional Chinese medicines and provides an anti-cervical erosion suppository and a preparation method thereof. The anti-cervical erosion suppository is prepared from ginsenoside, lithospermum, golden cypress, sophora flavescens, dried alums and acacia catechu. The preparation method comprises the following steps: grinding the acacia catech and the dried alums into fine powder; grinding borneol; adding water into the golden cypress, the sophora flavescens and the lithospermum and decocting for three times; mixing decoction solutions and filtering; adding ethanol and standing for 24 hours; recycling the ethanol and concentrating into thick paste; drying and crushing into fine powder; uniformly mixing with the fine powder; additionally adding base materials including polyoxyl stearate and polyethylene glycol 1500; mixing, heating and smelting; and adding the fine powder and uniformly agitating to prepare a suppository. The anti-cervical erosion suppository has good water solubility, no stimulation, no toxin, no anaphylaxis, and is stable in physicochemical property; the anti-cervical erosion suppository is not easily deformed due to moisture absorption and is not easy to mildew; at a room temperature, the anti-cervical erosion suppository has suitable rigidity and has no deformation and crushing in a packaging, transporting and storing process.

The invention discloses a gastrodin injection and a preparation method thereof. The gastrodin injection comprises gastrodin which is an active constituent, an accessory and water for injection. A prescription process is simplified through a large number of experiments, and the accessory only consists of buffer salt which has the effects of pH regulation and stabilization. The gastrodin injection does not contain organic solvents, auxiliary solvents, antioxidants and metal ion complexing agents, thereby improving the safety of clinical medicines and reducing the cost. Proved by pharmacological experiments, the gastrodin injection does not have anaphylaxis, irritant reactions and hemolytic reactions and can guarantee the medicine safety. The gastrodin injection has the advantage of solving the problems of reduced content and unstable pH value of the gastrodin injection in the process of storage, has simple prescription, good stability, low production cost, guarantees of medicine quality and safety and can be stored for two years at normal temperature.

The invention discloses probiotic powder capable of resisting anaphylaxis in the technical field of foods or health-care foods. The probiotic powder capable of resisting anaphylaxis consists of the components of 300-1000 parts of galactooligosaccharide, 300-800 parts of isomaltooligosacharide, 400-900 parts of yeast beta-glucan, 100-300 parts of lactobacillus paracasei, 100-300 parts of lactobacillus rhamnosus, 100-300 parts of lactobacillus reuteri, 100-300 parts of lactobacillus acidophilus, 100-300 parts of bifidobacterium longum, an excipient and a diluent. According to the probiotic powder capable of resisting anaphylaxis disclosed by the invention, an allergy immunity adjusting and controlling treatment method is adopted, the immune system of a human body is strengthened through a natural immunity adjusting and controlling element, and the probiotic powder is suitable for people of any age level and is more suitable for pregnant female parents to use; and the generation probability of allergy constitutions of newborn can be reduced by the probiotic powder, wherein five kinds of bacteria of the lactobacillus paracasei, the lactobacillus rhamnosus, the lactobacillus reuteri, the lactobacillus acidophilus and the bifidobacterium longum are powerfully combined, so that the allergy constitutions can be effectively improved, bacterial colonies which are officially safe are adopted, and the probiotic powder is free from any side effects.

The invention relates to rice protein yoghurt and a preparation method thereof. The method comprises the following steps of: preparing rice protein slurry; preparing additive solution; mixing milk, rice protein slurry and additive solution, and homogenizing; sterilizing the obtained homogenous liquid, and cooling; then, inoculating lactic acid bacteria TY367 and lactic acid bacteria TY971, and fermenting; and after the fermentation is over, refrigerating and performing after-ripening to obtain the rice protein yoghurt. Through the rice protein yoghurt, complementary nutrition of animal/plant protein can be realized, nutrition balance is obtained, and a human body can obtain balanced and proper amount of amino acid, thereby greatly improving the nutritional and biological values of milk; and moreover, the rice protein does not cause any anaphylaxis, thus possible anaphylaxis caused by adding other plant proteins is avoided.

The invention discloses a Japanese saussurea herb extracting solution as well as a preparation method and application thereof. The Japanese saussurea herb extracting solution prepared in a water extract manner is obtained by a lot of experiments and researches of the inventor. The Japanese saussurea herb extracting solution has the characteristic that skin contact anaphylaxis is significantly removed, so that cosmetics containing the Japanese saussurea herb extracting solution have good action on people with sensitive skin, and the using effects of the cosmetics on people with sensitive skin are improved.

The present invention is directed to pharmaceutical compositions and methods of using combination therapies containing a SYK inhibitor, or a pharmaceutically acceptable salt thereof, and a antineoplastic or antiinflammatory agent for the treatment of inflammatory, autoimmune and cell proliferative diseases, such as allergic reaction, transplant rejection, rheumatoid arthritis (RA), lupus, multiple sclerosis (MS) or psoriasis undesired acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL), non-Hodgkin lymphoma (NHL) (including diffuse large B cell lymphoma (DLBCL)), mantle cell lymphoma, acute lymphocytic leukemia (ALL), follicular lymphoma, Burkitt's lymphoma, small Lymphocytic (SLL), Lymphoma, multiple myeloma, asthma, vasculitis, Idiopathic thrombocytopenic purpura (ITP), Heparin Induced Thrombocytopenia (HIT) and hemolytic anemia.

The invention discloses a composition with anti-wrinkling and skin brightening effects, a mask and a preparation method of the mask. The composition is prepared from, by weight, 8-30 parts of aloe barbadensis superfine powder, 6-26 parts of aloe barbadensis leaf juice and 20-42 parts of fresh bletilla striata tuber extract. The bletilla striata anti-wrinkling and skin brightening mask is composed of traditional Chinese medicine effective components and auxiliary materials capable of being accepted in the mask field and has the anti-wrinkling and skin brightening effects, the formula is simple and effective, and no irritation and anaphylaxis are generated to the skin; the fresh bletilla striata tuber extract and the aloe barbadensis leaf juice are greatly combined by mixing effective components and dissolved to generate more effective substances; and according to main components of bletilla striata, cell activity improving, anti-wrinkling, skin whitening and skin brightening are achieved, fresh aloe barbadensis is adopted, moistening, nourishing, anti-wrinkling and whitening are achieved, and the effective components of the bletilla striata are effectively enhanced.

The invention discloses a whitening cosmetic and a preparation method of the whitening cosmetic. The whitening cosmetic comprises the following raw materials by weight percent: 50-70wt% of cucumber seed oil, 15-25wt% of Hypericum perforatum oil and 15-25wt% of calendula oil. The preparation method of the whitening cosmetic comprises the following steps of: mixing 50-70wt% of cucumber seed oil, 15-25wt% of Hypericum perforatum oil and 15-25wt% of calendula oil at the temperature of 20-25DEG C, and evenly stirring to obtain a product. The whitening cosmetic disclosed by the invention is made from the natural plant oil, green, safe, and free of stimulation to the skin; the whitening cosmetic is discovered to be not only good in whitening effect, but also very good in effect for fading the chromatosis, repairing the sensitive skin, repairing the scar remained by pimples and whelk, i.e. acne marks, acne holes and the like after being tried out by 780 customers; the whitening cosmetic can refine the pores, and is good in effect for curing the sunburn and the skin light sensitivity; and the whitening cosmetic is free of anaphylaxis.

The invention provides a production process of a soy sauce flavor type soybean sauce. The soy sauce flavor type soybean sauce is prepared by using vinasse as a raw material, and aspergillus oryzae strains and bifidobacterium strains as strains. The production process is characterized in that with vinasse as the raw material, the production cost is reduced; and meanwhile, with bifidobacterium as a fermenting strain, the prepared soybean sauce contains nutritional ingredients such as lipoteichoic acid, membrane teichoic acid and peptidoglycan, so that the soybean sauce is endowed with a unique flavor, and the soybean sauce has the efficacies of enhancing the immunologic function and anti-tumour effect of the organism, relieving and removing fatigue, adjusting balance of intestinal microflora and improving the liver function, has nutritional benefits, and also has the efficacies of relieving uremia, resisting anaphylaxis, increasing the appetite, reducing blood pressure and blood cholesterol, preventing arteriosclerosis and the like, so as to promote health of a human body. The soybean sauce prepared by the production process is dark in color, and thick in juice, contains sugar but is not sweet, contains salt but is not salty, contains acid but is not sour, and has the unique thick soy sauce flavor.

The invention particularly relates to an anti-anaphylaxis beverage and a preparation method thereof. The anti-anaphylaxis beverage is mainly prepared from the following raw materials in parts by weight: living drinking water, oligosaccharide, nonfat dry milk powder, glucose, high fructose corn syrup, pectin, lactobacillus paracasei and lactobacillus plantarum LP28. According to the anti-anaphylaxis beverage disclosed by the invention, the lactobacillus plantarum LP28 has the anti-anaphylaxis efficacy; the oligosaccharide can strengthen the immunity of organisms through proliferating beneficial bacteria such as bifidobacteria in intestinal tracts; the lactobacillus paracasei has high stress resistance and probiotic characteristics, so that the antioxidative efficacy is improved. The beverage disclosed by the invention can effectively strengthen the immunity of organisms; besides, compared with the simplex lactobacillus plantarum LP28, the beverage has the advantages that the quantity of first-type T lymphocyte (Th1) secreted interferons gamma (Interferon-gamma) is increased by 30%, and the secretion of second-type T lymphocyte (Th1)IL-4 is reduced by 24. The beverage is good in anti-anaphylaxis effect and worth popularization.

The invention relates to a traditional Chinese medicine micro emulsion aerosol for curing rheumatism bone ache, in particular to a micro emulsion aerosol administration preparation. The aerosol comprises traditional Chinese medicine muskone, dragons blood, frankincense and myrrh gum; oil phase mainly comprises mixed aromatic plant oil (paroline, cinnamon oil, eugenol type basil oil, eucalyptus oil and gaultherolin); compound penetrant comprises laurocapram, borneol, muskone and dementholized peppermint oil; the aerosol also comprises an emulsifier, a cosolvent and a propellant; the preparation forms nano micro emulsion (25 to 80 nm); and the aerosol performs nanocrystallization homogeneity to precious traditional Chinese medicine in the preparation and spreads the precious traditional Chinese medicine to a microemulsified system, the microemulsified system adopts an oily system W/O with good biological adhesiveness to skin, medicine can be directly infiltrated into skin and directly reach wounded parts, and effects of rapid pain stopping and inflammation diminishing are achieved. Compared with frankincense rheumatism plaster, the aerosol has better local permeability, has no skin irritation and anaphylaxis, and is rapid for pain stopping.

The invention belongs to the field of medical embolization devices, relates to a sodium alginate microsphere targeted vascular embolization agent containing an antineoplastic drug and a preparation method thereof. Alginic acid is taken as a pharmaceutical carrier, the antineoplastic drug etoposide is a pharmaceutical active ingredient, divalent metal cation or calcium ion solution is taken as a solidifying agent, and the sodium alginate encapsulates the etoposide to prepare ideal particle size-controllable sodium alginate microspheres comprising the etoposide, thus avoiding toxic side effect of traditional etoposide administration such as anaphylaxis and inconvenience. The vascular embolization agent changes the dosage form and route of administration way of the antineoplastic drug etoposide, has high efficacy and low toxicity, and is safely and effectively applied to clinical application. The vascular embolization agent has the advantages of mild preparation condition and simple and convenient operation, and is fit for large-scale production. The vascular embolization agent can be used for vascular embolization, local targeted tumor treatment, and treating small-cell carcinoma of the lung, oophoroma, carcinoma of testis, gastric cancer and liver cancer by administering the vascular embolization agent during operations.

The invention relates to An in vitro method of evaluating the immunological activity of a vaccine preparation in the form of a mixture of a molecular antigen and a carrier, wherein the mixture comprises a liquid phase and a solid phase, to which at least a part of the antigen is attached, the method comprising the steps of i) subjecting the vaccine to one or more measurements selected from the group consisting of: 1) the immunological activity of the mixture, 2) the immunological activity of antigen in the liquid phase, 3) the immunological activity of antigen in the solid phase, 4) the immunological activity of antigen in the liquid phase upon a treatment of the mixture to displace the antigen from the solid phase, and 5) the immunological activity of antigen in the solid phase upon a treatment of the mixture to displace the antigen from the solid phase, wherein the immunological activity measurement is selected from the group consisting of a) antibody binding capacity using an immunoassay employing an antigen-specific antibody bound to an antibody solid phase, b) ability to activate effector cells and c) potential for inducing anaphylaxis; and ii) using the measurement results to evaluate the immunological activity of the vaccine.

The invention provides a ganoderma pill and a processing method thereof, belonging to the processing field of ganoderma. With an alcohol-extracted ganoderma extract as the main material and shell-broken ganoderma lucidum spore powder as the auxiliary material, the processing technique comprises the following steps of: choosing the alcohol-extracted ganoderma extract subjected to ethanol tower type gradient diacolation extraction and the shell-broken ganoderma lucidum spore powder; stirring and uniformly mixing by using a stirring machine, making into pills, drying, packaging with coating outside the pills, cooling and sizing to obtain the ganoderma pills. The ganoderma pill disclosed by the invention solves a problem that the content of the effective component of the ganoderma contained in the traditional product is low; in particular, the content of the special triterpene matter in the ganoderma is increased, so that the action time on human bodies is prolonged, the effects of lowering blood pressure and decreasing blood sugar are improved, the body's immunity is regulated, the anti-anaphylaxis and the sleeping quality are improved. The ganoderma pill solves the problems that the ganoderma pill in the prior art is big in dosage, unobvious in pharmacodynamic effects, long in effect-initiating time and poor in taste.

The invention relates to a Chinese herbal compound microemulsion gel emplastrum, and its preparation method and application. In particular, the invention relates to a microemulsion gel emplastrum composition. The microemulsion gel emplastrum composition comprises methyl salicylate, menthol, camphor, borneol, traditional Chinese medicine extract containing active ingredients such as paeonol, eugenol and piperine, a microemulsion matrix, a hydrophilic polymer framework material, a binder, a cross-linking agent, a cross-linking regulator, etc., wherein the active ingredients are entrapped in the microemulsion. The invention further relates to a preparation method for the microemulsion gel emplastrum composition and application of the microemulsion gel emplastrum composition to blood circulation invigoration and pain relieving. The microemulsion gel emplastrum composition in the invention not only ensures high-degree integration of drugs and the matrix, and also has the characteristics of low irritation to skin, little anaphylaxis, good transdermal absorption performance, simple preparation process, etc.

Provided are methods for suppressing IgE and IgG-mediated allergic reactions through monoclonal antibody applications. More specifically, methods are herein provided for safe induction of rapid desensitization. Specific embodiments are herein provided for suppressing allergic reactions in a subject, including specific methods of providing a monoclonal antibody selected from the group consisting of anti-FcαRIa and anti-FcγRIIb/RIII; administering the antibody to a subject at a dose that is lower than the level required to induce shock; and administering sequentially escalating doses of the monoclonal antibody so as to induce rapid desensitization to an allergen, thereby suppressing allergic reaction in the subject.

The invention relates to the technical field of food production processes, and provides a preparation method of linseed nougat. The preparation method of linseed nougat comprises the following steps: gel preparing, sugar dissolving, boiling, pulp flushing, beating for inflating, mixing and blending, product molding and packaging, thereby obtaining the finished product. The prepared linseed nougat contains 10-20% of cooked linseed prepared by a cold baking technique, linseed contains rich unsaturated fatty acids omega-3 series (alpha-linolenic acid) and omega-6 series (gamma-linolenic acid), lignan, EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), and the linseed has important effects of regulating blood lipid, reducing cholesterol, preventing emphraxis, reducing blood viscosity, preventing and curing diabetes, reducing blood pressure, reducing weight, inhibiting anaphylaxis, diminishing inflammation, protecting eyesight, enhancing the intelligence of adolescents and the like. The linseed nougat is soft and fluffy in texture, fine in structure, fragrant and sweet in taste and thick in milk fragrance, and has a nutritional health care property, good soft and chewy mouthfeel and strong practicability.

The invention relates to an externally applied traditional Chinese medicine composition for treating umbilical hernia and an umbilical hernia treating bag containing lychee seed and rhizoma cimicifugae. The traditional Chinese medicine composition is prepared from radix astragali, angelica, bighead atractylodes rhizome, rhizoma cimicifugae, radix bupleuri, dried orange peel, toosendan fruit, Evodia rutaecarpa, lychee seed, fennel, clove, asarum, safflower and the like. The umbilical hernia treating bag comprises a bellyband body and fastening belts, wherein the inner side of the bellyband body is provided with a square or circular inner bag, and a medicine core pad containing the traditional Chinese medicine composition is filled in the inner bag. In the invention, traditional Chinese medicines with the functions of tonifying middle-Jiao and qi, soothing the liver and strengthening the spleen are used for umbilical skin absorption and physical support for treating infantile umbilical hernia. By utilizing the externally applied traditional Chinese medicine composition, the defect of long treatment course in self-recovery and conservative treatment of umbilical hernia and the defect that the sick children can feel painful in the operative treatment are solved. The invention has the characteristics of obvious curative effect and short treatment course, and the patients can not feel painful and have no skin irritation symptom or anaphylaxis. The invention is suitable for children with tender viscera, is also suitable for clinical features of children, and can promote the children with umbilical hernia to grow up healthily. The raw materials in the prescription are conventional traditional Chinese medicines, thus, the invention has the advantages of wide raw material sources, low cost and simple technique, and is easy for popularization.