222 results about "Clinical research" patented technology

The invention relates to the technical field of electric digital data processing, and discloses an intelligent data processing method for clinical research. The method comprises the following steps: constructing a basic clinical knowledge graph fused with an international medical ontology; the method comprises the following steps: performing deep learning driven entity recognition and knowledge graph linking on original data from heterogeneous sources such as an electronic medical record and an inspection system; executing cross-source entity alignment and knowledge fusion based on the graph attention network; performing automatic data quality verification and restoration according to clinical logic rules embedded in the atlas; and finally, extracting and generating a standardized analysis ready data set from the enhanced atlas according to research requirements. According to the technical scheme, high-quality, automatic and semantic integration and flexible delivery of clinical research data are realized, and the data processing efficiency and research reliability are improved.

Methods, systems, and apparatus, including computer programs encoded on computer storage media, for managing and adapting monitoring programs. In some implementations, a system communicates with a set of remote devices involved in a monitoring program that involves collection of data from the remote devices over a communication network. The system determines a set of attributes associated with an outcome or condition that has occurred for multiple of the remote devices. The system generates parameters to adapt the monitoring program, and the system selects a second group of remote devices to involve in the adapted monitoring program based on profiles or sets of attributes of users associated with the remote devices. The system configures the remote devices in the selected second group to perform monitoring for the adapted monitoring program, including acquiring data for the adapted monitoring program and providing the acquired data to a server over the communication network.

The technical scheme of the invention discloses an orthopedic implant patent value evaluation system, which is characterized by comprising an orthopedic implant evaluation reference standard data acquisition module, an orthopedic implant patent data integration module, a multi-source data feature construction module, an orthopedic implant patent comprehensive value evaluation model and an evaluation and result output module. The invention provides an orthopedic implant series patent value evaluation and analysis system for identifying high-quality, convertible and investable orthopedic implant patents, and can combine legal, economic, technical and other patent evaluation indexes with clinical research data, supervision systems, clinical guidelines and the like. Dynamic evaluation and prospective prediction are carried out on the value of a series of orthopaedic implant patents, market data and a machine learning algorithm are introduced, an industrial exclusive evaluation platform is constructed, a system value of achievement transformation-patent value evaluation is established, and scientificity, adaptability and practicability of an evaluation result are ensured.

The invention discloses a traditional Chinese medicine composition for treating gastroesophageal reflux disease and a preparation method and application thereof.The traditional Chinese medicine composition is prepared from ginger processed pinellia, poria cocos, semen armeniacae amarae, thunberg fritillary bulb, radix paeoniae alba, pericarpium citri reticulatae, cuttlebone, cassia twig, moutan bark, concha arcae, honey-fried licorice root and the like. Clinical research results show that the qi-regulating and backflow-inhibiting decoction provided by the invention can remarkably improve clinical symptoms of patients with gastroesophageal reflux diseases, can remarkably improve psychological health feelings of the patients with gastroesophageal reflux diseases, and is high in treatment effective rate, low in recurrence rate and good in safety.

The application discloses a point application traditional Chinese medicine composition with an effect of treating irritable bowel syndrome, a point application plaster and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The application provides a point application traditional Chinese medicine composition and a point application plaster. The traditional Chinese medicine composition comprises the following components: psoralea, radix codonopsis, dried zedoary, fried atractylodes, mace, schisandra chinensis and evodia. The composition is prepared according to the principle of less medicine and special function and treatment of disease and seeking the origin. The core tonifying medicine, psoralea, dried zedoary and radix codonopsis, has a prominent dosage proportion and remarkable effects of warming the spleen and kidney yang and invigorating the spleen and replenishing qi. The application finds through clinical research that the clinical total effective rate of the test group is 76.7%, the curative effect is accurate and better than that of a placebo, the IBS-SSS score, the TCM syndrome score and the stool character score of IBS patients can be reduced, the symptoms of the patients are improved, and the composition can effectively treat IBS.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for promoting blood circulation, excreting dampness and reducing blood pressure and a preparation method and application thereof. The active ingredient of the traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 3-10 parts of prepared radix aconiti lateralis preparata, 5-15 parts of rhizoma zingiberis, 5-15 parts of honey-fried licorice root, 5-15 parts of wine-processed radix cyathulae, 10-30 parts of radix salviae miltiorrhizae, 10-30 parts of radix paeoniae rubra, 10-30 parts of radix puerariae, 10-30 parts of rhizoma alismatis and 5-15 parts of radix platycodonis. The traditional Chinese medicine has the effects of tonifying deficiency, dispelling excess, promoting blood circulation, excreting dampness, reducing blood pressure and strengthening the body resistance, not only strengthens healthy qi to treat root causes, but also promotes blood circulation, excretes dampness to treat symptoms, and achieves the effect of treating both symptoms and root causes. Clinical research shows that the traditional Chinese medicine composition can promote blood circulation, excrete dampness and support healthy qi, so that the blood pressure level of a hypertensive patient is reduced, and the purpose of effectively treating hypertension is achieved.

The invention discloses a human immortalized pure renal cyst cell line SRC-X1 and application thereof, and belongs to the field of microbial animal cell lines. The human immortalized pure renal cyst cell line is named as SRC-X1, the cell line is preserved in the China Center for Type Culture Collection on September 19, 2025, and the preservation number is CCTCC NO: C2025303. The human immortalized pure renal cyst cell line SRC-X1 is applied to preparation, screening or evaluation of renal cyst treatment drugs. The invention also discloses the application of the human immortalized pure renal cyst cell line SRC-X1 as a renal cyst cell model. The human immortalized pure renal cyst cell line SRC-X1 is applied to renal cyst basic or clinical research as an experimental material.

The invention discloses an artery compression hemostasis device capable of monitoring pressure. The artery compression hemostasis device comprises a compression hemostat, a pressure sensing chip, a pressure display dial plate, a pressurization mechanism and a database. Compression pressure is converted into a visual numerical value through the pressure sensing chip and the display dial plate, medical staff can adjust according to the standard, hemostasis operation is standardized, and the hemostasis failure rate is remarkably reduced; a patient individual feature-pressure range corresponding system is established according to pressure values, medical staff adjust pressure in combination with a blood coagulation report, one person can press one pressure, and the occurrence rate of complications caused by pressure mismatching is reduced; pressure abnormity is reminded in real time through dial plate color early warning, medical staff can adjust the pressure in time conveniently, the pressure is controlled dynamically, and the comfort and safety of a patient are improved; by means of clear numerical values and early warning identifiers, the operation process is standardized, and the training period of green nurses is shortened; pressure dynamic change data can be recorded in real time, and support is provided for related clinical research.

The invention discloses a traditional Chinese medicine composition for treating spleen-kidney yang deficiency type osteoporosis, a preparation and application, and belongs to the technical field of traditional Chinese medicine, the traditional Chinese medicine composition is prepared from, by weight, 9-12 g of rhizoma curculiginis, 9-12 g of herba epimedii, 8-10 g of radix morindae officinalis, 8-10 g of radix angelicae sinensis, 3-6 g of cortex phellodendri, 3-6 g of rhizoma anemarrhenae, 9-12 g of radix rehmanniae praeparata, 10-15 g of rhizoma discoreae, 8-10 g of fructus psoraleae, 8-10 g of radix rehmanniae recen, 9-12 g of cortex eucommiae, 8-10 g of rhizoma chuanxiong, 12-15 g of poria cocos and 3-6 g of radix glycyrrhizae. The traditional Chinese medicine composition is suitable for spleen-kidney yang deficiency type osteoporosis. The traditional Chinese medicine composition can be used for treating deficiency-heat syndrome, deficiency-cold syndrome and phlegm-stasis collateral obstruction syndrome, so that the aim of treating according to symptoms is fulfilled. The prescription disclosed by the invention has the effects of strengthening the body resistance to eliminate pathogenic factors and treating both symptoms and root causes aiming at osteoporosis caused by spleen-kidney yang deficiency, bone withering and marrow reduction, blood stasis blockage and meridian obstruction. Clinical research shows that the medicine composition can effectively improve the symptoms such as intolerance of cold, lassitude and loose and firm muscles of osteoporosis patients after long illness, and is good in safety.

The invention provides an intelligent processing system for hospital medical record informatization management, and the system comprises a data storage module which is used for carrying out the butt joint with an existing information system of a hospital through an API gateway, constructing an original database through cloud object storage, and carrying out the centralized storage of structured medical record data and unstructured medical record data; and the term standardization module is used for mapping the medical terms in the medical record to a national standard medical term set. According to the method, automatic analysis, recognition and relation extraction are performed on the text information in the medical record through the medical natural language processing engine, and the text information is filled into the structured data model, so that the medical record information is standardized, and a good basis is provided for clinical scientific research and hospital management. By integrating patient information, historical medical records and medical knowledge maps, diagnosis suggestions and safe medication early warning are provided for doctors in the diagnosis and treatment process, the scientificity of clinical decision making is enhanced, medical risks are reduced, and patient safety is improved.

Disclosed are a clinical research data analysis method capable of real-time analysis and a device therefor. The clinical research data analysis method according to an embodiment of the present invention may comprise: a data collection step for collecting clinical research data input to an electronic data collection system; a data analysis processing step for generating a data analysis result by performing real-time analysis or statistical analysis by using the collected clinical research data as an input; and a service processing step for converting the data analysis result into a preset report format and providing same to at least one clinical research-related institution.

This invention discloses a kidney pathology image processing method integrating multi-tissue segmentation and quantitative lesion analysis, belonging to the field of medical image processing technology. The method includes the following steps: acquiring and preprocessing PAS-stained whole-slice images of kidney pathology; fine-tuning the segmentation model using an unsupervised domain adaptive strategy to address batch-to-batch staining differences; inputting the preprocessed image into a multi-class semantic segmentation neural network to obtain tissue segmentation results; training the network based on pixel-level annotations, employing a Class-Token mechanism, encoder-decoder architecture, and multi-scale feature fusion, and optimizing the Dice loss and binary cross-entropy loss based on joint weighting of categories and boundaries; performing statistical analysis based on the segmentation results and outputting quantitative analysis results. This invention provides an objective, reproducible, and intelligent auxiliary tool for the accurate assessment and large-scale clinical research of chronic kidney disease.

This utility model discloses an improved semen DNA collection card for assisted reproductive technology, belonging to the field of medical supplies technology. It includes a folding card with an upper cover, a lower cover, and a bottom surface. The bottom surface is located between the upper and lower covers. The lower cover has a sampling filter paper surface, and a PVC diaphragm is provided in the middle of the sampling filter paper surface to divide it into a pre-processing semen collection area and a post-processing semen collection area. This utility model stores the patient's unprocessed semen in the pre-processing semen collection area and the processed semen in the post-processing semen collection area. The PVC diaphragm between the two areas prevents interference and cross-contamination between the two semen samples, facilitating DNA comparison before and after semen processing. The folding card also facilitates transportation and transfer, allowing for the storage of both pre- and post-processing semen within a single card, which is beneficial for clinical research.

The invention relates to the technical field of medical literature data processing and artificial intelligence, and discloses a random contrast test (RCT) bias risk automatic evaluation method and system, and the method comprises the steps: obtaining RCT literature data containing a text, a table and a flow chart, and a RoB2 evaluation problem set; a problem reconstruction module injected through medical knowledge; performing position decision and multi-modal coordination analysis on the RCT literature through a multi-modal document analysis module; the reconstructed evaluation problem and the analyzed context information are input into a multi-expert cooperation module, cooperative reasoning is performed through a multi-reasoning unit, results are fused through a decision unit, and item-level, field-level and overall bias risk evaluation results are generated. The invention also constructs bias risk entry level and domain level data sets for supporting the training and verification of the method. The system comprises a data acquisition module, a problem reconstruction module, a document analysis module and a collaborative evaluation module, all the modules work cooperatively, automatic evaluation of RoB2 whole-process bias risks is achieved, and the system can be applied to scenes such as evidence-based medical research, system evaluation and clinical research quality control.

The application discloses a fluorescence enhancement anchor agent based on a fluoroboron dipyrrin-tetrazine dye for inflation microscopy technology, and belongs to the technical field of biochemical analysis. The fluorophore of the fluorescence enhancement anchor agent is shown in formula (I), formula (II) or formula (III): the tetrazine group carried by the fluorescence enhancement anchor agent is removed from fluorescence quenching through a biological orthogonal reaction with a drug probe, and the drug probe is shown in formula (IV): the fluorescence enhancement anchor agent can covalently and non-covalently anchor small molecules in a hydrogel network based on a tetrazine biological orthogonal reaction, and realizes inflation microscopic fluorescence imaging of a double fluorescence enhancement mechanism. In addition, the drug probe selects a non-covalent drug, gefitinib, as a probe core, is modified with a BCN click handle, and successfully realizes in-situ fluorescence inflation microscopic imaging of an EGFR drug-target, thereby providing a new tool for research and clinical research on non-covalent drug target co-localization information of exosomes.

This invention relates to the application of LAG3 agonists in the preparation of drugs for hematoma clearance after intracerebral hemorrhage (ICH) and the application of LAG3 in regulating hematoma clearance after ICH, belonging to the field of biomedical technology. This invention utilizes a mouse ICH model to first inject a LAG3 neutralizing antibody (C9B7W) via orthotopic injection, clarifying that LAG3 can regulate the phagocytic function of microglia after ICH and participate in hematoma clearance, revealing its potential molecular target for enhancing microglia phagocytic function and promoting hematoma clearance. Furthermore, overexpression of LAG3 after ICH is demonstrated. Lag3 The study confirmed that enhanced phagocytic function of microglia accelerated hematoma clearance, demonstrating that LAG3 agonists can be used as drugs for hematoma clearance after intracerebral hemorrhage. The experimental results of this invention make it possible to apply LAG3 to the prognostic treatment of ICH, thereby advancing basic and clinical research on endogenous hematoma clearance after ICH.

The invention relates to an image processing method and system for a temporary research project checklist. The system selects a to-be-uploaded inspection report through a first terminal according to a selected visit plan, and desensitizes the to-be-uploaded inspection report to obtain a first inspection report; transmitting the first inspection report to a data processing end; the second terminal determines follow-up visit details to be shot according to the selected target object, obtains an inspection report according to the follow-up visit details to be shot, desensitizes the inspection report to obtain a second inspection report, binds the second inspection report with the follow-up visit type, and transmits the bound second inspection report to the data processing end; the data processing end obtains the follow-up form of the target object through the edc system, identifies the characters in the first inspection report or the second inspection report in the follow-up form through the AI, obtains the character content in the first inspection report or the second inspection report, and displays the character content. The method has the advantages that the technical effect of improving the data processing efficiency and accuracy is achieved.

The application relates to a multi-agent collaborative clinical scientific research implementation method and device and computer equipment. The method comprises the following steps: in response to a user's clinical scientific research text input operation, generating demand information, obtaining a search instruction through dialogue interaction hub analysis, and obtaining a first preset number of candidate data sets through a medical data set management agent; after the user selects, a training data set is determined, a data set instruction is obtained by combining the search instruction and the training data set, a second preset number of candidate algorithms are generated by an algorithm management agent, the user selects and determines a training algorithm and generates a configuration file; based on the training algorithm and the configuration file, a third preset number of candidate algorithm power schemes are generated through an algorithm power scheduling module, the user selects and determines a training scheme and generates a training configuration file; a clinical scientific research algorithm is obtained through iterative training based on the file, an inference configuration file is generated in response to an inference text input, and finally an inference report is generated. The method can automatically implement clinical scientific research.

This invention discloses an environmental parameter sensing and adaptive adjustment system and method based on a photoconductive film. It integrates six-dimensional environmental sensors—light intensity, ultraviolet radiation, temperature, humidity, air pressure, and air quality—at the edge of the photoconductive film, and utilizes the film's directional light guidance and stray light filtering mechanisms to reduce environmental interference. The system includes an environmental sensing module, an environmental parameter processing module, a health data interface module, a correlation analysis module, an adaptive adjustment module, and an environmental early warning module. The correlation analysis module has preset environmental-health correlation patterns such as low temperature-increased blood pressure, high humidity-decreased blood oxygen, high ultraviolet radiation-skin health, poor air quality-respiratory diseases, and sudden changes in air pressure-headaches and joint pain, set based on clinical research data. The adaptive adjustment module pairs with smart home devices through a unified identity authentication center, sending control commands via Wi-Fi / Bluetooth / infrared to automatically adjust air conditioners, humidifiers, dehumidifiers, air purifiers, and lighting according to environmental parameters. The environmental early warning module supports single-indicator early warning, correlation early warning, trend early warning, and seasonal disease early warning, with customizable thresholds. The multi-environmental data fusion module uses weighted averaging and the 3σ principle for anomaly removal, integrating data from multiple devices such as mobile phones, watches, vehicles, and smart home devices. The sensors are automatically calibrated daily using meteorological bureau data, with the calibration process simultaneously linked to health data. This invention solves the problems of scattered environmental sensing devices, disconnect from health data, and inability to proactively adjust, serving as the infrastructure for intelligent health management.

The application belongs to the field of microbial animal cell lines, and relates to a human immortalized simple renal cyst cell line SRC-X1 and an application thereof. The human immortalized simple renal cyst cell line is named SRC-X1, the cell line has been preserved in the China Center for Type Culture Collection on September 19, 2025, and the preservation number is CCTCC NO: C2025303. The application of the human immortalized simple renal cyst cell line SRC-X1 in preparation, screening or evaluation of renal cyst treatment drugs. The application of the human immortalized simple renal cyst cell line SRC-X1 as a renal cyst cell model. The application of the human immortalized simple renal cyst cell line SRC-X1 as experimental material in renal cyst basic or clinical research.

A device may establish communication between the plurality of intelligent injection devices and an artificial intelligence-powered clinical research platform configured to manage a clinical trial or research program. A device may analyze, via the artificial intelligence platform, clinical trial protocol requirements including study design parameters, randomization schemes, blinding protocols, and adverse event monitoring requirements to generate coordinated medication administration strategies across the plurality of intelligent injection devices. A device may apply research protocol constraints to restrict medication selection, dosage calculations, administration timing, and patient assignment across the plurality of intelligent injection devices. A device may generate real-time coordination instructions through the artificial intelligence platform including synchronized administration timing across multiple sites, dosage verification protocols for different treatment arms, and compliance monitoring procedures tailored to specific research protocol requirements.

The invention belongs to the technical field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition for excreting dampness and strengthening heart as well as a preparation method and application thereof. The active ingredient of the traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 3-10 parts of prepared radix aconiti carmichaeli, 5-15 parts of rhizoma zingiberis, 5-15 parts of honey-fried licorice root, 10-30 parts of radix pseudostellariae, 5-15 parts of wine-processed radix cyathulae, 10-30 parts of radix salviae miltiorrhizae, 3-10 parts of pericarpium citri reticulatae, 10-30 parts of rhizoma alismatis and 5-15 parts of radix platycodonis. The traditional Chinese medicine has the effects of tonifying deficiency, dispelling excess, tonifying qi, nourishing yin, excreting dampness and promoting blood circulation, treating root causes by tonifying qi and nourishing yin and treating symptoms by excreting dampness and promoting blood circulation, and achieving the effect of treating both symptoms and root causes. Clinical research shows that the traditional Chinese medicine composition not only can reduce the plasma NT-proBNP level of a patient with ejection fraction retention type heart failure, but also can improve the score of the patient in the Life Quality Scale of Clinical Myocardiopathy Patient, and can be used for treating related diseases such as ejection fraction retention type heart failure and the like.

This invention belongs to the field of biology, specifically relating to a composition and its use against foot-and-mouth disease virus (FMDV). This invention discovered that compounds Pasireotide and Oxyclozanide alone cannot significantly inhibit FMDV replication. Unexpectedly, the combined use of Pasireotide and Oxyclozanide significantly inhibits the expression of FMDV RNA polymerase 3D protein, reducing the half-maximal tissue-cell infection dose (TCID) of FMDV. 50 It can significantly reduce the replication ability of foot-and-mouth disease virus and has the effect of antagonizing foot-and-mouth disease virus infection; and there are currently no clear clinical studies or drug instructions mentioning that there is a direct physical / chemical incompatibility between the two, so it can be used to prepare drugs against foot-and-mouth disease virus and has good application prospects.

The invention provides a traditional Chinese medicine compound for non-lactation period mastitis and application thereof, and relates to the technical field of traditional Chinese medicine pharmacy, the traditional Chinese medicine compound comprises cornu cervi degelatinatum, pseudobulbus cremastrae seu pleiones, baked ginger, semen brassicae, phryma leptostachya, adenophora tetraphylla, dandelion, ampelopsis japonica, tangerine pith, red halloysite and liquidambar formosana hance. Animal experiments show that the traditional Chinese medicine compound can effectively reduce the mammary gland induration volume of rats in a non-lactation period, reduce the mammary gland inflammation index of model rats and effectively inhibit the overexpression of key proinflammatory factors TNF-alpha and IL-6 in pathological tissues; clinical research shows that the traditional Chinese medicine compound can effectively relieve breast lumps, pains, red swelling and other core clinical symptoms of non-lactation period mastitis patients, remarkably improve the life quality of the patients and lower the serum SP and PRL levels at the same time. In conclusion, the traditional Chinese medicine compound for treating the non-lactating mastitis is definite in curative effect and clear in mechanism, a safe and effective traditional Chinese medicine scheme is provided for treating the non-lactating mastitis, and the traditional Chinese medicine compound has a good application prospect.

The present disclosure relates to a method for detecting off-target of gene editing system (OliTag-seq), which comprises: integrating double-stranded oligodeoxynucleotide (dsODN) into the double-stranded break position of the genomic DNA of a cell, amplifying the part of the genomic DNA containing the integrated dsODN, sequencing the amplified part of the genomic DNA, thereby detecting the double-stranded break in the genomic DNA of the cell; wherein the length of the double-stranded oligodeoxynucleotide (dsODN) is 35bp-200bp, and each of the 3' end and 5' end of the dsODN contains 1-3 GC DNA pairs. The method of the present disclosure can effectively identify the off-target sites induced by gene editing system, and compared with the existing methods, it shows higher sensitivity in identifying off-target sites, and has wide application prospects in the fields of disease diagnosis and risk assessment, clinical research and drug development, transgenic biological technology, etc.

The invention provides a probiotic strain formula scheme screening method. The method comprises the following steps: establishing a disease model database according to a clinical examination result, performing standardization processing and data layering on the disease model database to obtain a layered database, scoring and grading diseases in the layered database, and establishing a disease model grading data matrix of patients; establishing a strain curative effect matrix according to the strain database and published clinical research data; and associating the disease model grading data matrix with the strain curative effect matrix, screening a relationship with high association strength, constructing a disease-microbial treatment response model, and obtaining different types and different levels of diseases and corresponding recommended bacterial systems through the disease-microbial treatment response model. And grading the synergistic effect of the disease and the recommended strain, filtering the score through a threshold value to screen out a scheme of a strain formula, and outputting the scheme of the strain formula through a user interface.

Provided herein are methods for administering hepatitis B virus surface antigen (HBsAg) to a subject suffering from chronic hepatitis B to differentiate between responder subjects and non-responder subjects that the administration of HBsAg results in an increased response to HBV antibody levels, and treating chronic hepatitis B in responder subjects using HBV therapy. Also provided are methods of excluding unresponded subjects outside a clinical study.

The invention discloses a full life cycle intelligent supervision method and system oriented to somatic cell clinical research, and relates to the technical field of somatic cell clinical research supervision. Based on the associated evidence atlas, intelligent auditing is achieved, and an interpretable report is generated; an in-process real-time supervision stage: real-time acquisition and verification of physical parameters, operation specifications and follow-up visit data are realized through an Internet of Things sensor, computer vision and an intelligent terminal; and a post-event intelligent auditing and tracing stage: integrating full-process data based on the unique ID of the project to form a digital file, mining compliance defects by using a deep learning model, and realizing credible tracing through a block chain. According to the invention, the problems of high manual dependence, blind monitoring areas, difficulty in tracing and full-flow splitting in traditional supervision are solved, automatic, intelligent and traceable supervision of the whole life cycle of somatic cell clinical research is realized, and the supervision efficiency and accuracy are improved.

The invention discloses a method for establishing an oligoasthenospermia model by using alpha-ketoglutaric acid. Alpha-ketoglutaric acid is added into drinking water of animals to obtain the oligoasthenospermia model. According to the invention, alpha-ketoglutarate (alpha-KG) is added into drinking water of a male mouse, so that the oligoasthenospermia mouse model is successfully established. The invention provides a new thought and clue for deeply researching the pathogenesis of oligoasthenospermia and researchers of male reproductive health, and has important scientific and medical values for understanding the mechanism of male infertility, developing a new therapy, evaluating the treatment effect and promoting related clinical research.

The invention provides an intelligent axillary crutch device, relates to the technical field of medical rehabilitation equipment, and solves the problem that traditional axillary crutches can only provide mechanical support and cannot perform quantitative monitoring and datamation management on rehabilitation indexes. The device comprises a walking stick body, and a chip module assembly integrating a central processing module and a wireless communication module is arranged in a waterproof cavity below an armpit support; a data acquisition module is arranged at the side pipe, the grip and the base and comprises a pressure sensor, a motion sensing assembly and a heart rate and pulse sensor. The data acquisition module acquires multi-dimensional motion parameters, the multi-dimensional motion parameters are processed into structured rehabilitation data through an algorithm of the central processing module, the structured rehabilitation data are transmitted to the terminal in real time through the wireless communication module, breakpoint resume is supported, quantitative monitoring and datamation management of rehabilitation indexes are achieved, accurate rehabilitation requirements are met, and meanwhile data support is provided for clinical research.