The invention discloses an
esophageal cancer prognosis risk
analysis method and
system based on
machine learning, and a medium, and relates to the technical field of
artificial intelligence technology and
bioinformatics, and the method comprises the steps: 1, collecting multi-
modal data of a patient, and carrying out the
standardization processing, so as to construct a stable
feature set; 2, constructing a plurality of
machine learning models, realizing high and low risk group prediction of each
machine learning model based on stable
feature set modeling, and determining the
machine learning model and an optimal
feature set according to the high and low risk group prediction; and step 3, calculating SHAP interaction values among the features in the optimal feature set, drawing an interaction value curve according to the SHAP interaction values to obtain TopA interaction feature pairs, taking the interaction feature pairs as newly constructed features to be included in the original feature set in the step 1, and repeating the
feature screening process in the step 1 and the step 2 to obtain an optimal
machine learning model. Predicting high and low
risk groups of patients; according to the prognosis risk
analysis method, the detection specificity of high and low
risk groups of local advanced
esophageal cancer patients is greatly improved.