54 results about "Glucose test" patented technology

A measurement module for glucose testing includes a glucose testing measurement module housing, a test strip receptacle formed in the housing, and a connector portion formed in the housing and shaped to permit mechanical removable attachment of the housing to a hand-held computer. Electronics determine the amount of glucose present in a sample of body fluid, when the test strip is positioned in the receptacle and the body fluid is placed on a test strip, and communicate the glucose amount to the hand-held computer via the connector portion.

Method and system for providing a subscription based replenishment transaction of consumable items such as glucose test strips including a data network, a user terminal operatively coupled to the data network, the user terminal configured to receive and transmit data over the data network, and a server terminal operatively coupled to the data network, the server terminal configured to receive from the user terminal a request for establishing an account associated with a consumable item, receive from the user terminal one or more predetermined parameters associated with the account, and generate the account based on the one or more predetermined parameters, where the one or more predetermined parameters include a user specified consumable replenishment level received from the user terminal is disclosed.

An improved disposable glucose test strip for use in a test meter of the type which receives a disposable test strip and a sample of blood from a patient and performs an electrochemical analysis using a non-conductive integrated reagent / blood separation layer (17) containing a filler, an enzyme effective to oxidize glucose, e.g., glucose oxidase, and a mediator effective to transfer electrons from the enzyme. The integrated layer formulation is printed over a conductive carbon element (16) to form a working electrode. The filler, for example a silica filler, is selected to have a balance of hydrophobicity such that on drying it forms a two-dimensional network on the surface of the conductive element. The response of this test strip is essentially temperature independent over relevant temperature ranges and is substantially insensitive to the hematocrit of the patient.

Various embodiments are described and illustrated to calculate an insulin bolus, recommend such bolus, and provide reminder messages for performing an additional glucose test.

A wearable blood glucose measuring device based device and kit that incorporates non-continuous, invasive, electrochemical glucose test strip technologies for measuring blood glucose concentrations. The device can be inconspicuously worn due to its compact nature and integration into commonly worn articles such as watches, bracelets, armbands, wristbands, and the like. All-in-one embodiments include integrated test strip management including automatic test strip dispensing / ejection as well as incorporating spring loaded lancet apparatus capable of the dispensing, arming and activating functions enabling the user to provide a blood sample for glucose testing. Some embodiments do not integrate, nor contain any lancing devices / lancets. Other embodiments contain secure storage compartments integrated into the wearable blood glucose measuring device where the user can choose to store loose glucose test strips, calibration strips, lancets, cleaning wipes, and any combination thereof.

An improved disposable glucose test strip for use in a test meter of the type which receives a disposable test strip and a sample of blood from a patient and performs an electrochemical analysis is made using a non-conductive integrated reagent / blood separation layer containing a filler, an enzyme effective to oxidize glucose, e.g., glucose oxidase, and a mediator effective to transfer electrons from the enzyme. The integrated layer formulation is printed over a conductive carbon element to form a working electrode. The filler, for example a silica filler, is selected to have a balance of hydrophobicity and hydrophilicty such that one drying it forms a two-dimensional network on the surface of the conductive element. The response of this test strip is essentially temperature independent over relevant temperature ranges and is substantially insensitive to the hematocrit of the patient.

The invention discloses a siphon test paper, which pertains to the technical field of bio-sensor. The substrate of the test paper is printed with a working electrode, a reference electrode, an electrical circuit and an interface port connected with a read-out instrument. The working electrode and the reference electrode are composed of carbon coatings which are printed on the substrate at once and printed with a reaction working coating, the components by weight percentage include: 12 to 16 percent of enzyme, 15 to 20 percent of a conducting medium, 10 to 20 percent of an adhesive and 42 to 60 percent of buffer. Two sides of the reaction coating are bonded with a double-sided adhesive layer which is adhered with a hydrophilic membrane that is convenient for sucking sample blood and can limit the quantity of sample blood. The invention applies a screen printing method to produce the siphon glucose test paper at high speed and on large scale. The quality indexes of the test paper such as repeatability and precision further can limit the quantity of samples owning to the improvement of the sampling and introduction structure of the test paper, thereby improving quality and greatly reducing production cost. Raw materials applied can be obtained from various resources, processing is simple, technique maneuverability is strong and the test paper is suitable for large scale industrial production. Once the test paper of the invention sucks human blood, results can be read out conveniently and visually from a corresponding matching testing instrument.

The present invention is a method of preventing reuse of test strips for measuring an analyte or indicator such as glucose in a physiological fluid such as blood, interstitial fluid, or urine. The present invention also relates to a method of preventing reuse of test strips incorporating an integrated lance such as a needle, blade, or other sharp or skin puncturing device. Certain types of medical devices such as, for example, glucose test strips were intended to be tested only once and then disposed. This requirement is often needed because the reagent chemistry in many test strips is not suitable for measuring glucose a second time. However, it is possible that some user will accidentally test a previously used test strip. This could potentially become a problem if the glucose meter attempts to make a glucose measurement and outputs a result. Therefore, it is desirable that a single use test strip and meter have a prescribed method for preventing a previously tested test strip from being reused.

The present invention provides an electrochemical biosensor. The biosensor includes a substrate; a metal layer disposed on the substrate, wherein a first end of the metal layer is formed with a reaction region by a working electrode and a reference electrode provided on the metal layer, the reaction region is applied with an enzyme so that an electrical response is generated when the enzyme and a test sample form a chemical reaction, and a second end of the metal layer is provided with an integrated information unit to provide both test sample information and coding information.

The invention discloses a matching test paper for a glucose tester and a preparation method thereof, which pertain to the technical field of bio-sensor. The substrate of the test paper is printed with a working electrode, a reference electrode and an electrical circuit; one end of the substrate is printed with a conducting wire connected with a read-out instrument; the working electrode and the reference electrode are carbon coatings which are printed on the substrate at once and printed with biological enzyme, a medium and an adhesive. The method adopts bio-sensor and electrochemical principle, produces the test paper by screen printing which is not restricted to a conductive circuit as well as prints relatively sensitive bio-components directly on an electrode holder; screen printing area is fully controlled by a screen printing machine. The encapsulation of the test paper adopts siphon encapsulation which limits reaction space. Once the test paper of the invention contacts human blood, a limited quantity of blood is sucked into a reaction tank and accurate results can be obtained conveniently and visually from a corresponding matching testing instrument. The glucose test paper has the advantages of simple production method, high accuracy and low cost and is convenient for later process and encapsulation and good for scale production.

The various embodiments disclosed herein are devices that deliver electrical stimulation and / or vibration stimulation to the surface of skin in proximity to insulin injections and / or glucose testing in order to decrease or eliminate the pain of these procedures.

An improved disposable glucose test strip for use in a test meter of the type which receives a disposable test strip and a sample of blood from a patient and performs an electrochemical analysis is made using a non-conductive integrated reagent / blood separation layer containing a filler, an enzyme effective to oxidize glucose, e.g., glucose oxidase, and a mediator effective to transfer electrons from the enzyme. The integrated layer formulation is printed over a conductive carbon element to form a working electrode. The filler, for example a silica filler, is selected to have a balance of hydrophobicity and hydrophilicity such that one drying it forms a two-dimensional network on the surface of the conductive element. The response of this test strip is essentially temperature independent over relevant temperature ranges and is substantially insensitive to the hematocrit of the patient.

A test strip for confirming a desired proportion of components in dialysate, including a first medium capable of indicating the concentration of bicarbonate ion, and a second medium capable of indicating the concentration of glucose. The test strip defines a first region impregnated with the first medium, and a second region impregnated with the second medium. The test strip optionally includes a third medium capable of indicating the pH of the dialysate. The third medium is impregnated at a third region on the test strip. Alternatively, the test strip comprises a bicarbonate test pad attached to the first region, a glucose test pad attached to the second region, and optionally a pH test pad attached to the third region. The glucose test pad is impregnated with the first medium, the glucose test pad is impregnated with the second medium, and the pH test pad is impregnated with the third medium.

The invention discloses a visible blood glucose test strip and a preparation method thereof. The visible blood glucose test strip is structurally formed by compounding saturating paper base materials and Millipore nano filter membrane with the bottom face being coated with adhesive. The preparation method comprises the following steps: preparing impregnant solution, preparing the saturating paper base materials, and compounding the saturating paper base materials and the Millipore nano filter membrane. When the test strip is used for blood glucose detection, blood is filtered by the membrane, color development reaction of chromogen reagent, assistant color development reagent and H2O2 is utilized, a special electrochemical signal detection device has no need to be used, so that the effect that blood glucose concentration is quickly and conveniently detected can be achieved. Compared with the test strip with polypropylene, polyethylene, polrvinyl chloride and polycarbonate base materials in the prior art, plant fiber paper base materials of the test strip disclosed by the invention are renewable natural resources, and have the advantages of favorable biodegradation and low price, and the test strip disclosed by the invention can be stored for at least three months at room temperature.

The invention belongs to a micro-biosensor and particularly relates to a manufacturing method of a silica-based integratable micro-glucose sensor. The existing glucose sensor takes a glucose oxidase electrode as a device for molecular recognition and signal conversion, thus having poor stability and restricting the application of the glucose sensor on the basis of enzyme. The manufacturing method comprises the following steps of: manufacturing a silicon micro-channel by using a P-typed single-side polishing silicon wafer through electrochemical etching; depositing the silicon micro-channel in eletroplating solution without electricity at the temperature of 80 DEG C for 30-45 minutes; and taking out and washing the silicon micro-channel with deionized water, and obtaining the silica-based integratable micro-glucose sensor. The invention has the advantages that: the electrochemical process is adopted, the cost is low, and the operation is simple; the micro-channel has even porosity, and the ratio of the specific surface area to the depth is big; the eletroplating solution without electricity has simple preparation and low price; no influence on the glucose test is generated; three-dimensional structure is beneficial to the contact between the glucose and active substances, and the improvement of the oxidation current; and the micro-biosensor is beneficial to the exchange reaction of ions and is miniaturized and integrated, thus being beneficial to large-scale production.

The invention belongs to the field of urine analysis and detection, relates to urine glucose test paper capable of resisting ascorbic acid interference and a preparation method thereof and solves thetechnical problem of existence of ascorbic acid interference in the detection of urine glucose in an existing dry chemistry test paper. The urine glucose test paper capable of resisting ascorbic acidinterference is formed by a substrate and filter paper fixedly arranged on the substrate. The test paper is obtained by being immersed into immersion liquid consisting of a buffer solution, glucose oxidase, peroxidase, potassium iodide, ascorbic acid oxidase, anti-interference substance xanthan gum, a surfactant, an enzyme stabilizer and a blue dye substance, so that anti-VC interference capability of the glucose test paper with potassium iodide as the substrate can be significantly improved, and sensitivity and accuracy of the detection result are enhanced; and the glucose detection result isnot influenced when the content of the VC in the sample does not exceed 3.5mmol / L. The preparation method of the urine glucose test paper capable of resisting ascorbic acid interference is simple andeasy to operate, stable in performance and accurate in test result.

The various embodiments disclosed herein are devices that deliver electrical stimulation and / or vibration stimulation to the surface of skin in proximity to insulin injections and / or glucose testing in order to decrease or eliminate the pain of these procedures.

Various embodiments are described and illustrated to calculate an insulin bolus, recommend such bolus, and provide reminder messages for performing an additional glucose test.

The invention discloses a portable test tube for detecting glucose. A hydrogel is used as a carrier, the glucose is oxidized by glucose oxidase and generated into hydrogen peroxide, and then, a glucose sample is detected through the chromogenic reaction, which is catalyzed by molybdenum disulfide, between the hydrogen peroxide and a color developing agent. The problems in the prior art, such as high requirements on glucose detecting operation, complicated detection process, high detecting cost, long detecting time, big background interference can be solved. The glucose test tube has the advantages of low cost, simplicity in operation, capability of visually and rapidly detecting the glucose content in the sample, and convenience in carry and storage.

The invention discloses a method for online automatic detection of permanganate index in water. The method comprises the following steps: preparing a used reagent; finishing calibration of a standardcurve, and verifying the accuracy and repeatability of online automatic detection equipment and glucose test; manually testing different types of surface water and standard solutions thereof in a laboratory according to a national standard method to obtain permanganate indexes in the surface water; testing the corresponding surface water and the standard solution thereof by online automatic detection equipment to obtain absorbance; enabling the online automatic detection equipment to calculate permanganate indexes in different types of surface water according to the standard curve; and comparing a laboratory method with an automatic calculation method, calculating a relative error, and judging whether the relative error is within a standard requirement range. By using the method provided by the invention, the accuracy and repeatability of the online automatic detection equipment are good, the glucose test and the adding standard recovery rate meet the requirements, and the method has great significance for environmental protection in the field of online monitoring of surface water quality.

The invention discloses a portable urinalysis test paper capable of reducing interference. The urinalysis test paper comprises a substrate, test paper blocks arranged on the substrate, and isolation pads arranged among the test paper blocks, wherein the test paper blocks on the substrate sequentially comprise an ascorbic acid test paper block, a pH test paper block, a specific gravity test paper block, a protein test paper block, a glucose test paper block, a calcium ion test paper block, an occult blood test paper block, a urobilinogen test paper block, a bilirubin test paper block, a ketonebody test paper block, a creatinine test paper block, a leukocyte test paper block, a microalbumin test paper block, a nitrite test paper block and compensation pad arranged from one end of the substrate to the other end of the substrate. By optimizing the sequence of test strips and designing the isolation pads among the test paper blocks, the mutual interference is reduced; potassium iodate andsodium chlorate reagents are added into textured layers of the test paper blocks to reduce the interference of ascorbic acid, a reagent block for detecting the ascorbic acid is correspondingly added to serve as accuracy of the contrast inspection result, and thereby the influence of the ascorbic acid is reduced to the maximum extent.

A test strip for confirming a desired proportion of components in dialysate, including a first medium capable of indicating the concentration of bicarbonate ion, and a second medium capable of indicating the concentration of glucose. The test strip defines a first region impregnated with the first medium, and a second region impregnated with the second medium. The test strip optionally includes a third medium capable of indicating the pH of the dialysate. The third medium is impregnated at a third region on the test strip. Alternatively, the test strip comprises a bicarbonate test pad attached to the first region, a glucose test pad attached to the second region, and optionally a pH test pad attached to the third region. The glucose test pad is impregnated with the first medium, the glucose test pad is impregnated with the second medium, and the pH test pad is impregnated with the third medium.

A glucose test device includes a casing, a carrying unit, consumables, a first push rod, a locking component, a first driving unit and a control unit. The carrying unit is disposed at the casing. The consumables are disposed in the carrying unit. The first push rod is movably disposed at the casing. The first push rod is suitable for moving to push one consumable out of the carrying unit. The locking component is movably disposed at the casing. The first driving unit is connected to the locking component. The control unit is electrically connected to the first driving unit. The control unit is suitable for controlling the first driving unit to drive the locking component to lock the first push rod as unmovable. The control unit is suitable for controlling the first driving unit to drive the locking component to release the first push rod.