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A surgical coupling device detachably connects a tool holder to a surgical instrument, wherein the tool holder is provided with a recess into which a coupling portion of the instrument can be inserted detachably, wherein a locking recess is provided in an inner wall of the recess, with which a locking member can be engaged detachably, the locking member being supported at the instrument, wherein the locking member is selectively movable into a locking position and a release position by a servo drive.

The invention relates to a microfabricated device for the rapid detection of DNA, proteins or other molecules associated with a particular disease. The devices and methods of the invention can be used for the simultaneous diagnosis of multiple diseases by detecting molecules (e.g. amounts of molecules), such as polynucleotides (e.g., DNA) or proteins (e.g., antibodies), by measuring the signal of a detectable reporter associated with hybridized polynucleotides or antigen / antibody complex. In the microfabricated device according to the invention, detection of the presence of molecules (i.e., polynucleotides, proteins, or antigen / antibody complexes) are correlated to a hybridization signal from an optically-detectable (e.g. fluorescent) reporter associated with the bound molecules. These hybridization signals can be detected by any suitable means, for example optical, and can be stored for example in a computer as a representation of the presence of a particular gene. Hybridization probes can be immobilized on a substrate that forms part of or is exposed to a channel or channels of the device that form a closed loop, for circulation of sample to actively contact complementary probes. Universal chips according to the invention can be fabricated not only with DNA but also with other molecules such as RNA, proteins, peptide nucleic acid (PNA) and polyamide molecules.

There is provided an optical device including a light-transmitting substrate having at least two major surfaces and edges, optical means for coupling light into the substrate by total internal reflection and at least one partially reflecting surface located in the substrate.

The invention relates to a lens antenna which comprises a metal loudspeaker (4) and a lens (1), wherein the metal loudspeaker (4) is provided with a feed source; the feed source is embedded in the smaller-diameter end of the metal loudspeaker (4), and the lens (1) is embedded in the larger-diameter end of the metal loudspeaker (4); the lens (1) comprises a core plate (2); the core plate (2) is a planar dielectric plate, and one of the planes is provided with a plurality of core-plate disresonance basic units; a core-plate metal square frame (5) is printed in each core-plate disresonance basicunit; and the areas of the core-plate disresonance basic units and the core-plate metal square frames (5) gradually decrease from the center to the edge of the core plate (2). As the core plate (2) is planar, the lens (1) is easy to manufacture. In addition, the lens (1) also comprises matching plates (3) positioned on both sides of the core plate (2). The matching plates (3) can reduce the reflection of the electromagnetic waves on the interface of the lens (1) and the air.

A thin film transistor structure in which a source electrode and a drain electrode formed from a metal material are in direct contact with an oxide semiconductor film may lead to high contact resistance. One cause of high contact resistance is that a Schottky junction is formed at a contact plane between the source and drain electrodes and the oxide semiconductor film. An oxygen-deficient oxide semiconductor layer which includes crystal grains with a size of 1 nm to 10 nm and has a higher carrier concentration than the oxide semiconductor film serving as a channel formation region is provided between the oxide semiconductor film and the source and drain electrodes.

A sensor network collects time-series data from a process tool and supplies the data to an analysis system where pattern analysis techniques are used to identify structures and to monitor subsequent data based on analysis instructions or a composite model. Time-series data from multiple process runs are used to form a composite model of a data structure including variation. Comparison with the composite model gives an indication of tool health. A sensor network may have distributed memory for easy configuration.

A method, apparatus, and system of flexible multi-touch touch are provided. The invention comprising: a flexible layer; and one or more sensors configured to detect a plurality of simultaneous touching positions at distinct locations of the layer and to generate distinct signals representative of the locations for each of the touches. And a method for flexible touch panel comprising: driving one or more sensors; and detecting a plurality of simultaneous touching positions at distinct locations of a touch panel, wherein the touch panel comprising a flexible property. The invention is also directed towards a flexible multi-touch screen device, comprising: a display as user interface; and a multi-touch panel with flexible property to combine with the display configured to detect a plurality of simultaneous touching positions at distinct locations of the multi-touch panel.

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

The system described herein enables clinicians and researchers to use aggregated genetic and phenotypic data from clinical trials and medical records to make the safest, most effective treatment decisions for each patient. This involves (i) the creation of a standardized ontology for genetic, phenotypic, clinical, pharmacokinetic, pharmacodynamic and other data sets, (ii) the creation of a translation engine to integrate heterogeneous data sets into a database using the standardized ontology, and (iii) the development of statistical methods to perform data validation and outcome prediction with the integrated data. The system is designed to interface with patient electronic medical records (EMRs) in hospitals and laboratories to extract a particular patient's relevant data. The system may also be used in the context of generating phenotypic predictions and enhanced medical laboratory reports for treating clinicians. The system may also be used in the context of leveraging the huge amount of data created in medical and pharmaceutical clinical trials. The ontology and validation rules are designed to be flexible so as to accommodate a disparate set of clients. The system is also designed to be flexible so that it can change to accommodate scientific progress and remain optimally configured.

Storage stability of an assay device, comprising an assay strip and sensitive reagents such as antibodies within a plastics casing, is maintained by moulding some or all of the casing from dessicant-containing plastics material, especially a blend of about 60-65% polystyrene and about 30% silica dust. Ideally the desiccant-containing plastics material is used in the moulding of a removable cap for the device. The cap can be made by sandwich injection moulding, using the dessicant-containing polystyrene as a core, surrounded by conventional polystyrene.

An objet of the present invention is to provide a semiconductor device with a new structure. Disclosed is a semiconductor device including a first transistor which includes a channel formation region on a substrate containing a semiconductor material, impurity regions formed with the channel formation region interposed therebetween, a first gate insulating layer over the channel formation region, a first gate electrode over the first gate insulating layer, and a first source electrode and a first drain electrode which are electrically connected to the impurity region; and a second transistor which includes a second gate electrode over the substrate containing a semiconductor material, a second gate insulating layer over the second gate electrode, an oxide semiconductor layer over the second gate insulating layer, and a second source electrode and a second drain electrode which are electrically connected to the oxide semiconductor layer.

Provided is a forceps tip assembly capable of supporting a forceps tip with high rigidity in order to realize a laparoscopic surgery requiring a significant power with the forceps tip, such as an organ removal surgery which has been heretofore difficult to be performed by a robot for medical use. The forceps tip assembly includes: a forceps tip supporting member which has a supporting part for supporting a forceps tip and three leg parts which are disposed at even intervals in a circumferential direction around a central axis line C1 and fixed to the supporting part so as to protrude backward from the supporting part; and three back-and-forth moving members which are disposed at even intervals in a circumferential direction around a predetermined central axis line C2 extending in a front-to-rear direction, which have their front end portions coupled with the three leg pads swingably and slidably in a direction orthogonal to the predetermined central axis line C2 and which are mutually coupled together as relatively movable in the extending direction of central axis line C2.

As a display device has a higher definition, the number of pixels, gate lines, and signal lines are increased. When the number of the gate lines and the signal lines are increased, a problem of higher manufacturing cost, because it is difficult to mount an IC chip including a driver circuit for driving of the gate and signal lines by bonding or the like. A pixel portion and a driver circuit for driving the pixel portion are provided over the same substrate, and at least part of the driver circuit includes a thin film transistor using an oxide semiconductor interposed between gate electrodes provided above and below the oxide semiconductor. Therefore, when the pixel portion and the driver portion are provided over the same substrate, manufacturing cost can be reduced.

An ablation catheter having distal and proximal ends for performing ablation on a human tissue region comprises at least one electrode. These elements are formed on a conductive sheet situated at the distal end of the catheter. A flex circuit assembly couples the at least one electrode to a measurement and power circuit attached to the proximal end of the catheter. The measurement and power circuit supplies power to the at least one electrode via the flex circuit.

Peptide ligands having affinity for serum albumin are useful for tumor targeting. Conjugate molecules comprising a serum albumin binding peptide fused to a biologically active molecule demonstrate modified pharmacokinetic properties as compared with the biologically active molecule alone, including tissue (e.g., tumor) uptake, infiltration, and diffusion.

The present invention relates to novel lip / cheek probes for detection of pulse-based differences in light absorbence across the vascularized tissue of a lip or cheek of a patient. These probes are fabricated to provide signals to estimate arterial oxygen saturation, and / or to obtain other photoplethysmographic data. The present invention also relates to a combined probe / cannula. The present invention also relates to other devices that combine a pulse oximeter probe with a device supplying oxygen or other oxygen-containing gas to a person in need thereof, and to sampling means for exhaled carbon dioxide in combination with the novel lip / cheek probes. In certain embodiments, an additional limitation of a control means to adjust the flow rate of such gas is provided, where such control is directed by the blood oxygen saturation data obtained from the pulse oximeter probe.

There is provided an optical device including a light-transmitting substrate having at least two major surfaces and edges, optical means for coupling light into the substrate by total internal reflection and at least one partially reflecting surface located win the substrate.

The invention relates to a microfabricated device for the rapid detection of DNA, proteins or other molecules associated with a particular disease. The devices and methods of the invention can be used for the simultaneous diagnosis of multiple diseases by detecting molecules (e.g. amounts of molecules), such as polynucleotides (e.g., DNA) or proteins (e.g., antibodies), by measuring the signal of a detectable reporter associated with hybridized polynucleotides or antigen / antibody complex. In the microfabricated device according to the invention, detection of the presence of molecules (i.e., polynucleotides, proteins, or antigen / antibody complexes) are correlated to a hybridization signal from an optically-detectable (e.g. fluorescent) reporter associated with the bound molecules. These hybridization signals can be detected by any suitable means, for example optical, and can be stored for example in a computer as a representation of the presence of a particular gene. Hybridization probes can be immobilized on a substrate that forms part of or is exposed to a channel or channels of the device that form a closed loop, for circulation of sample to actively contact complementary probes. Universal chips according to the invention can be fabricated not only with DNA but also with other molecules such as RNA, proteins, peptide nucleic acid (PNA) and polyamide molecules.

A gallium containing crystalline material. The material comprises a bulk semi-polar gallium indium containing crystalline material having a thickness of about 20 nanometers to about 1000 nanometers. The material includes a spatial width dimension of no greater than about 10 microns characterizing the thickness of the bulk semi-polar gallium indium containing crystalline material. The material includes a photoluminescent characteristic of the crystalline material having a first wavelength, which is at least five nanometers greater than a second wavelength, which is derived from an indium gallium containing crystalline material grown on a growth region of greater than about 15 microns.

A display device includes a pixel portion in which a pixel is arranged in a matrix, the pixel including an inverted staggered thin film transistor having a combination of at least two kinds of oxide semiconductor layers with different amounts of oxygen and having a channel protective layer over a semiconductor layer to be a channel formation region overlapping a gate electrode layer and a pixel electrode layer electrically connected to the inverted staggered thin film transistor. In the periphery of the pixel portion in this display device, a pad portion including a conductive layer made of the same material as the pixel electrode layer is provided. In addition, the conductive layer is electrically connected to a common electrode layer formed on a counter substrate.

Provided is a method for controlling a wireless power transmitter transmitting wireless power to at least one wireless power receiver. The method for controlling a wireless power transmitter, according to the present invention, can comprise the steps of: receiving information related to a wireless power receiver from at least one of each of the wireless power receiver; and controlling each of a plurality of power transmitting units included in the wireless power transmitter on the basis of the information related to the wireless power receiver.

A phased array antenna system includes an RF front end, a radome, and an optical calibrator embedded in the radome for enabling in-situ calibration of the RF front end. The optical calibrator employs an optical timing signal generator (OTSG), a Variable Optical Amplitude and Delay Generator array (VOADGA) for receiving the modulated optical output signal and generating a plurality of VOADGA timing signals, and an optical timing signal distributor (OTSD). The in-situ optical calibrator allows for reduced calibration time and makes it feasible to perform calibration whenever necessary.

A lancet device, a tip for a lancet device and method of using the lancet device. The lancet device has a body portion for firing the lancet and a tip portion. The tip for a lancet device includes a front assembly which includes a side wall portion, a skin-engaging portion at least partially defining a plane beyond which a lancet needle may extend, and a lancet stop element, a slot is disposed in one of the sidewall portion and the lancet stop element, and at least one following element extending into the slot, wherein the lancet stop element is moveable towards and away from the plane in response to movement of the at least one following element. The method includes adjusting a set depth of penetration of the needle by moving the at least one following element, disposing the distal end of the lancet device against a surface of skin, and triggering the firing mechanism to cause the needle to penetrate the surface of the skin to the set depth, wherein the puncture allows a blood sample to be taken.

An atomizer for electronic cigarette comprises a mouth-piece, an atomization shell and a thread bushing. The atomization shell is a hollow pipe with its first end connected to the mouth-piece and second end sealed by a sealing sleeve and the thread bushing. An aerosol passage is provided inside the atomization shell. The aerosol passage has one end in communication with an orifice of the mouth-piece and another end communicating with the sealing sleeve muff-coupled to the thread bushing. The atomization shell has a first intermediary piece extending into the sealing sleeve for introducing tobacco liquid stored in the atomization shell into the sealing sleeve. An electric heater is provided between the sealing sleeve and the thread bushing. The electric heater heats up the tobacco liquid immerged in the first intermediary piece to make it atomized. The atomized tobacco liquid flows through the aerosol passage and is discharged through the mouth-piece.

As a display device has a higher definition, the number of pixels, gate lines, and signal lines are increased. When the number of the gate lines and the signal lines are increased, a problem of higher manufacturing cost, because it is difficult to mount an IC chip including a driver circuit for driving of the gate and signal lines by bonding or the like. A pixel portion and a driver circuit for driving the pixel portion are provided over the same substrate, and at least part of the driver circuit includes a thin film transistor using an oxide semiconductor interposed between gate electrodes provided above and below the oxide semiconductor. Therefore, when the pixel portion and the driver portion are provided over the same substrate, manufacturing cost can be reduced.

A micropump in which a fluid is pumped by the interaction of longitudinal acoustic waves and the fluid in the microchannel. The micropump having an acoustical transducer responsive to a high-frequency input and directing a longitudinal acoustic wave into the channel which induces a pressure gradient. The fluid in the channel flowing in the direction of travel of the acoustic wave in the channel.

An intensity distribution of an electric field of a high frequency power used for generating plasma is controlled by using an electrode made of a homogeneous material and a moving body. There is provided a plasma processing apparatus for introducing a processing gas into an evacuable processing chamber 100 and generating plasma by a high frequency power and performing a plasma process on a wafer W by the plasma. The plasma processing apparatus includes a dielectric base 105a having a multiple number of fine holes A; a varying member 200 as the moving body provided with a multiple number of rod-shaped members B capable of being inserted into and separated from the fine holes A; and a driving mechanism 215 configured to drive the varying member 200 to allow the rod-shaped members B to be inserted into and separated from the fine holes A.

A lifting sling and a lifting grommet are disclosed which can be fabricated of a high tensile strength polymeric material, preferably a woven polymer such as liquid crystal polymer fibers, that are woven in a rope or cable configuration. The apparatus features an elongated woven material length of cable that is spliced. Plastic, preferably polyurethane spring cut tube sleeves are positioned as a grip on the splices to allow for handling in the field without concern for the splice becoming disassembled or undone. The sling and grommet of the present invention can each be provided with a clear cover spring cut tube that serves as a flexible protective cover for minimizing abrasion and maintaining the slings appearance.

Apparatus and method for selectively engaging and securing an array of shelf dividers to a mounting device which is securable to a display shelf. In the first form a divider is characterized by a divider structure having an elongated vertical wall and elongated horizontal base that operates to divide, organize and support the displayed merchandise. A resilient latch located on the underside of the base of the divider structure selectively engages and secures the divider structure onto a mounting device comprising a receiving member running longitudinally along the length of the surface of the mounting device which is securable along the front edge of a display shelf. The latch and the receiving member each comprise reciprocating (i.e. complementary) protrusions to allow the cooperative engagement of the divider structure and mounting device, thus locking the divider member to and unlocking the divider member from the mounting device to permit the repositioning of the display as desired without necessitating removal of the merchandise from the display. In addition when the divider structure and mounting device are fully engaged, a second protrusion on the underside of the divider member cooperates with a flange or lip on the mounting device to prevent lateral movement of the divider structure and maintain the position of the divider perpendicular to the mounting device and the front edge of the shelf. In a second embodiment, the divider structure comprises a pusher track and a spring urged pusher assembly to automatically push merchandise to the front of the shelf. Another embodiment comprises a divider base without a vertical divider wall, and with or without a pusher track and spring urged pusher assembly, thus pushers and dividers can be used in various convenient combinations within a shelf management system.