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A surgical coupling device detachably connects a tool holder to a surgical instrument, wherein the tool holder is provided with a recess into which a coupling portion of the instrument can be inserted detachably, wherein a locking recess is provided in an inner wall of the recess, with which a locking member can be engaged detachably, the locking member being supported at the instrument, wherein the locking member is selectively movable into a locking position and a release position by a servo drive.

A riveting apparatus includes a hot air pipe; a connection pipe coupled to the hot air pipe; a forming tool having a configuration in which peripheral and center portions project downward and portions existing therebetween are curved upward, defined with discharge holes which extend in axial and radial directions, and coupled to a lower end of the connection pipe so that hot air having passed through the connection pipe can be discharged through the discharge holes to heat an end of a rivet to thereby allow the forming tool to form the end of the rivet into the shape of a head; a moving unit coupled to the hot air pipe or the connection pipe to move the forming tool upward and downward; and a guide surrounding the forming tool so that hot air discharged through the discharge holes can be directed toward the end of the rivet.

A method, apparatus, and system of flexible multi-touch touch are provided. The invention comprising: a flexible layer; and one or more sensors configured to detect a plurality of simultaneous touching positions at distinct locations of the layer and to generate distinct signals representative of the locations for each of the touches. And a method for flexible touch panel comprising: driving one or more sensors; and detecting a plurality of simultaneous touching positions at distinct locations of a touch panel, wherein the touch panel comprising a flexible property. The invention is also directed towards a flexible multi-touch screen device, comprising: a display as user interface; and a multi-touch panel with flexible property to combine with the display configured to detect a plurality of simultaneous touching positions at distinct locations of the multi-touch panel.

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

The system described herein enables clinicians and researchers to use aggregated genetic and phenotypic data from clinical trials and medical records to make the safest, most effective treatment decisions for each patient. This involves (i) the creation of a standardized ontology for genetic, phenotypic, clinical, pharmacokinetic, pharmacodynamic and other data sets, (ii) the creation of a translation engine to integrate heterogeneous data sets into a database using the standardized ontology, and (iii) the development of statistical methods to perform data validation and outcome prediction with the integrated data. The system is designed to interface with patient electronic medical records (EMRs) in hospitals and laboratories to extract a particular patient's relevant data. The system may also be used in the context of generating phenotypic predictions and enhanced medical laboratory reports for treating clinicians. The system may also be used in the context of leveraging the huge amount of data created in medical and pharmaceutical clinical trials. The ontology and validation rules are designed to be flexible so as to accommodate a disparate set of clients. The system is also designed to be flexible so that it can change to accommodate scientific progress and remain optimally configured.

The present invention relates to novel lip / cheek probes for detection of pulse-based differences in light absorbence across the vascularized tissue of a lip or cheek of a patient. These probes are fabricated to provide signals to estimate arterial oxygen saturation, and / or to obtain other photoplethysmographic data. The present invention also relates to a combined probe / cannula. The present invention also relates to other devices that combine a pulse oximeter probe with a device supplying oxygen or other oxygen-containing gas to a person in need thereof, and to sampling means for exhaled carbon dioxide in combination with the novel lip / cheek probes. In certain embodiments, an additional limitation of a control means to adjust the flow rate of such gas is provided, where such control is directed by the blood oxygen saturation data obtained from the pulse oximeter probe.

The invention relates to a microfabricated device for the rapid detection of DNA, proteins or other molecules associated with a particular disease. The devices and methods of the invention can be used for the simultaneous diagnosis of multiple diseases by detecting molecules (e.g. amounts of molecules), such as polynucleotides (e.g., DNA) or proteins (e.g., antibodies), by measuring the signal of a detectable reporter associated with hybridized polynucleotides or antigen / antibody complex. In the microfabricated device according to the invention, detection of the presence of molecules (i.e., polynucleotides, proteins, or antigen / antibody complexes) are correlated to a hybridization signal from an optically-detectable (e.g. fluorescent) reporter associated with the bound molecules. These hybridization signals can be detected by any suitable means, for example optical, and can be stored for example in a computer as a representation of the presence of a particular gene. Hybridization probes can be immobilized on a substrate that forms part of or is exposed to a channel or channels of the device that form a closed loop, for circulation of sample to actively contact complementary probes. Universal chips according to the invention can be fabricated not only with DNA but also with other molecules such as RNA, proteins, peptide nucleic acid (PNA) and polyamide molecules.

A gallium containing crystalline material. The material comprises a bulk semi-polar gallium indium containing crystalline material having a thickness of about 20 nanometers to about 1000 nanometers. The material includes a spatial width dimension of no greater than about 10 microns characterizing the thickness of the bulk semi-polar gallium indium containing crystalline material. The material includes a photoluminescent characteristic of the crystalline material having a first wavelength, which is at least five nanometers greater than a second wavelength, which is derived from an indium gallium containing crystalline material grown on a growth region of greater than about 15 microns.

A lancet device, a tip for a lancet device and method of using the lancet device. The lancet device has a body portion for firing the lancet and a tip portion. The tip for a lancet device includes a front assembly which includes a side wall portion, a skin-engaging portion at least partially defining a plane beyond which a lancet needle may extend, and a lancet stop element, a slot is disposed in one of the sidewall portion and the lancet stop element, and at least one following element extending into the slot, wherein the lancet stop element is moveable towards and away from the plane in response to movement of the at least one following element. The method includes adjusting a set depth of penetration of the needle by moving the at least one following element, disposing the distal end of the lancet device against a surface of skin, and triggering the firing mechanism to cause the needle to penetrate the surface of the skin to the set depth, wherein the puncture allows a blood sample to be taken.

An atomizer for electronic cigarette comprises a mouth-piece, an atomization shell and a thread bushing. The atomization shell is a hollow pipe with its first end connected to the mouth-piece and second end sealed by a sealing sleeve and the thread bushing. An aerosol passage is provided inside the atomization shell. The aerosol passage has one end in communication with an orifice of the mouth-piece and another end communicating with the sealing sleeve muff-coupled to the thread bushing. The atomization shell has a first intermediary piece extending into the sealing sleeve for introducing tobacco liquid stored in the atomization shell into the sealing sleeve. An electric heater is provided between the sealing sleeve and the thread bushing. The electric heater heats up the tobacco liquid immerged in the first intermediary piece to make it atomized. The atomized tobacco liquid flows through the aerosol passage and is discharged through the mouth-piece.

As a display device has a higher definition, the number of pixels, gate lines, and signal lines are increased. When the number of the gate lines and the signal lines are increased, a problem of higher manufacturing cost, because it is difficult to mount an IC chip including a driver circuit for driving of the gate and signal lines by bonding or the like. A pixel portion and a driver circuit for driving the pixel portion are provided over the same substrate, and at least part of the driver circuit includes a thin film transistor using an oxide semiconductor interposed between gate electrodes provided above and below the oxide semiconductor. Therefore, when the pixel portion and the driver portion are provided over the same substrate, manufacturing cost can be reduced.