162341 results about "Biomedical engineering" patented technology

The invention discloses a thrombus excision system. An embolus is extracted through a mechanical embolus extraction device, a blood vessel is dredged, and revascularization of the blood vessel is achieved. A saccule guide catheter is put at the near end of the embolus part when the embolus is extracted, blood flow is temporarily blocked, and thus a fine crushed embolus generated in the embolus extraction process is prevented from being flushed to the far end of the blood vessel; meanwhile, for a relatively large embolus, a part of thrombus can also be sucked by virtue of the saccule guide catheter, and then the residual thrombus can be extracted by virtue of a thrombus exsector. The thrombus exsector, the saccule guide catheter and a delivery microcatheter are arranged on the thrombus excision system disclosed by the invention, wherein the thrombus exsector is used as a main component, an excision spring is arranged, and the release state of the excision spring is a conical spiral state. Compared with the prior art, the thrombus excision system has the advantages that the thrombus exsector is very soft, the minimal through size is 0.014' (0.36mm), the thrombus exsector can easily enter a cerebral vessel, a near-end protection technology is adopted in the operation process, and thrombus suction is combined with mechanical embolus extraction, so that the success rate of the operation is improved, and the complications are reduced.

The present invention relates to the technical field of stomatology. Provided is an auxiliary dental implant generation method based on a diffusion model. The method in the present invention comprises: acquiring oral CBCT image data of historical patients, preprocessing the oral CBCT image data of the historical patients to obtain a CBCT image dataset, using the CBCT image dataset to train a multi-task segmentation network, and using the segmentation network to obtain an intraoral tissue segmentation result; using the intraoral tissue segmentation result to train detection networks from the three dimensions of a cross-sectional plane, a coronal plane and a sagittal plane, respectively; using the detection networks to obtain detection results in the three directions of the cross-sectional plane, the coronal plane and the sagittal plane; fusing the detection results in the three directions of the cross-sectional plane, the coronal plane and the sagittal plane, and using a majority voting algorithm to construct a three-dimensional bounding box, so as to acquire an edentulous area; and using the intraoral segmentation result and the edentulous area as prompt information to guide, by means of an iterative process, a network to generate a post-implantation effect. The implantation effect obtained by the present invention is highly accurate, thereby providing a more precise auxiliary tool for stomatology.

A system for monitoring hemodynamic status of a patient can include a transducer, an adapter and one or more monitor devices. The adapter may be in communication with the transducer and the one or more monitor devices. The adapter can be configured to receive and process data from the transducer such as unprocessed physiological data. The adapter can be configured to transmit data to the monitor device(s) such as processed and / or unprocessed physiological data. The adapter can be configured to generate, and transmit to the monitor devices(s), user interface data for rendering interactive graphical user interfaces to display information such as physiological information relating to a hemodynamic status of the patient. The adapter can be configured to receive and process, from the monitor device(s) user commands or instructions to control an operation of the system or its components.

An electrocardiogram device configured to transmit at least one signal responsive to a wearer's cardiac electrical activity can include a disposable portion and a reusable portion configured to mechanically and electrically mate with each other. The disposable portion can include a base having at least one mechanical connector portion, a plurality of cables and corresponding external ECG electrodes, and a first plurality of electrical connectors associated with the plurality of cables. The reusable portion can include a cover having at least one mechanical connector portion, a second plurality of electrical connectors configured to electrically connect with the first plurality of electrical connectors of the disposable portion, and an output connector port configured to transmit at least one signal responsive to one or more signals outputted by the external ECG electrodes of the disposable portion.

The AI-enhanced cellular modeling and simulation platform is a computational system designed to enhance biomedical research and development and personalized medicine and wellness. This platform integrates simulation modeling, machine learning and artificial intelligence, multi-omics data, and sophisticated data fusion and decision-support techniques to create comprehensive models of cellular systems and processes across multiple scales. It enables researchers and clinicians to simulate complex biological interactions, predict disease progression, and design or optimize treatment strategies or medical devices with improved accuracy and efficacy. The system's architecture allows for integration of various components, including real-time data processing, federated learning, and quantum computing enhancements. From personalized drug discovery and cancer therapies to synthetic biology and epidemiological analysis, this platform offers powerful tools for understanding and manipulating cellular systems and bioengineered systems. By bridging the gap between molecular-level interactions between cells and materials and organism-wide effects, it enables significant advancements in healthcare and biological sciences.

A blood pressure monitoring system, comprising: an exciter configured to produce an acoustic signal, the exciter being provided on a first substrate portion; a detector spaced apart from the exciter, the detector being configured to detect the acoustic signal and to produce an electrical output signal, the detector being provided on a second substrate portion that is mechanically or acoustically decoupled from the first substrate portion, wherein the detector comprises at least four detectors; and a processor configured to determine a blood pressure measurement from the electrical output signal.

A mechanical end effector for a humanoid robot includes a plurality of identical finger assemblies. Each of the finger assemblies is removably connected to a frame. Each of the finger assemblies is fully self-contained and operable independently of every other one of the finger assemblies and independently of every other component connected to the frame. Each of the finger assemblies includes a single electric motor and is configured to be fully operable using only the single electric motor.

A non-invasive physiological sensor system implemented as a smart watch or other wearable device includes an emitter for emitting light and a detector for collecting light after the light interacts with a tissue of a wearer. The system can measure light intensity at one or more radial distances to estimate attenuation parameter values that can be used to correct physiological parameter bias across subjects. In addition or alternatively, the system can determine whether a detector is positioned sufficiently proximate to an obstructing tissue (for example, an artery or vein) so as to cause inaccurate measurements by the detector.

A noninvasive blood pressure monitor. The noninvasive blood pressure monitor may include an inflatable cuff, a pressure transducer, one or more air pumps, and a processor. The processor may control the air pump(s) so as to initiate inflation of the cuff. The processor may also identify an oscillometric signal in an output of the pressure transducer, and may determine an envelope of the oscillometric signal. The processor may also determine one or more characteristics of the envelope of the oscillometric signal, and may control the air pump(s) so as to stop inflation of the cuff based on the one or more characteristics of the envelope of the oscillometric signal.

A system for perfusing an organ, for example a kidney or a heart. Preservation fluid can be pumped from a transport container to the organ through a cannula or organ adapter. A flow regulator valve can control the rate of flow of the preservation fluid based on renal resistance of the kidney or arterial resistance of the organ. The pump can operate at a rate independent of the arterial resistance.

A transport container for transporting an organ (T), such as a kidney, at hypothermic temperatures. The transport container comprises an inner lid (40) and a canister (38) that can be filled with preservation fluid. The preservation fluid can be pumped from the canister to the organ through a cannula. A flow regulator valve (48) can release the preservation fluid from the fluid path into the transport container at a rate based on at least one organ parameter (such as renal resistance of the kidney), whereas the pump can operate at a rate independent of the at least one organ parameter. The transport container may further comprise a fill port (28) and a vent port in the inner lid, and an organ rest (18).

The invention discloses a three-dimensional stomatognathic model reconstruction system based on multi-modal data fusion. The system comprises a multi-modal data input unit, a template deformation reconstruction unit, a registration fusion unit, a multi-source data integration unit and an output unit. Through fusion processing of a CBCT image, an oral cavity vision measurement model and facial scanning data, a body deformation algorithm is adopted to couple biomechanical characteristics to realize craniojaw template deformation, and a non-rigid ICP algorithm is combined for dynamic regulation and control to realize facial template adaptation. A deep neural network is innovatively constructed to segment CBCT gingival data, the CBCT gingival data is fused with an oral cavity vision measurement model, and high-precision tooth reconstruction is realized by applying a differential geometry multi-scale curvature field segmentation and adversarial edge optimization technology. Through a composite registration strategy combining adaptive rigid registration and non-rigid registration, an occlusal plane constraint mechanism and an orbital curvature extreme point matching algorithm are innovatively introduced, finally, multi-source data high-precision registration fusion is realized, and a three-dimensional oral-jaw system model with anatomical structure integrity and clinical precision can be generated.

A system configured to facilitate monitoring a patient when the patient transitions between environments. The system can have an in-room display terminal configured to display indicia of a health of the patient for electronically monitoring the health of the patient within a healthcare environment. The system can receive, via the in-room display terminal, a request to initiate monitoring the patient with the in-room display terminal at the healthcare environment; access historical physiological data associated with the patient and generated by a home monitoring device before the patient enters the healthcare environment; access real-time physiological data associated with the patient and originating from a physiological monitoring device coupled to the patient within the healthcare environment; generate one or more physiological parameters from the real-time physiological data and the historical physiological data; and cause the in-room display terminal to display indicia of the one or more physiological parameters.

A system for the hypothermic transport of biological samples, such as tissues, organs, or body fluids. The system includes a self-purging preservation apparatus to suspend a sample in preservation fluid and perfuse a tissue with preservation fluid. The self-purging preservation apparatus is placed in an insulated transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature.

This application is directed to systems, methods, and devices for image based analysis of plaque. In some embodiments, the approaches herein can be used for developing treatment plans, which can include local treatment, systemic treatment, or both. In some embodiments, the approaches herein can be used for stent selection. In some embodiments, the approaches herein can be used for surgical planning, which can include robotic surgical planning. In some embodiments, the approaches herein can be used for image normalization. In some embodiments, the approaches herein can be used for identifying plaque calcification thresholds. In some embodiments, the approaches herein can be used for identifying thin cap fibroatheroma. In some embodiments, the approaches herein can be used for coronary artery tree reconstruction. Some embodiments are directed to coronary artery disease risk stratification.

Systems and methods for cooling an organ to an individualized temperature based on organ parameters. A transport container can store the organ at a target temperature determined based on characteristics of the organ and the donor. A processor can determine the target temperature for preservation of the organ. The determination may be based on preservation time, the type of the organ, the age of the donor, the circulatory condition of the donor, the brain condition of the donor, and the metabolic rate of the donor.

The invention relates to the technical field of traditional Chinese medicine acupuncture and moxibustion teaching, in particular to a multi-view fused traditional Chinese medicine acupuncture and moxibustion visual teaching system which comprises a basic data construction module, an immersive environment building module, a multi-view interactive teaching module, a collaborative annotation conflict processing module, an annotation result auditing module and a model and data optimization module. Compared with the prior art, the traditional Chinese medicine acupuncture and moxibustion visual teaching method has the advantages that a new traditional Chinese medicine acupuncture and moxibustion visual teaching paradigm of data-driven cognition, interactive verification logic and intelligent optimization iteration is constructed through a closed loop of'problem definition-technical breakthrough-effect guidance ', space and modal limitations of traditional teaching are broken through, and the traditional Chinese medicine acupuncture and moxibustion visual teaching method is suitable for popularization and application. In addition, deep fusion of traditional Chinese medicine inheritance and modern medical education is achieved, and a reproducible digital solution is provided for standardized and precise acupuncture and moxibustion teaching.

A target location of a blood vessel is treated by providing an apparatus that includes a catheter and multiple shock wave discharge points positioned within a balloon along the catheter between proximal and distal ends of the catheter, wherein the distal end extends distally beyond the balloon and the proximal end extends proximally beyond the balloon. Shock waves are created by activating an electronic controller connected to an electrode at each shock wave discharge point. The shock waves are applied through the balloon to treat the target location with the shock waves.

The invention relates to the technical field of medical intelligent image recognition data processing, and discloses an image recognition and data analysis fused ultrasonic venipuncture system which comprises a multi-modal image acquisition module, an intelligent analysis processing module, a real-time navigation execution module and a complication early warning module. By arranging a multi-mode fusion sensing end, when vein puncture real-time navigation is carried out, through ultrasonic image, thermodynamic distribution and optical characteristic three-mode data collaborative registration, the consistency of deep blood vessel recognition is guaranteed, meanwhile, a three-dimensional topological model containing blood vessel elastic parameters is dynamically constructed, blood vessel position deviation can be calibrated in real time in the puncture process, and the accuracy of vein puncture is improved. The accuracy of blood vessel positioning is guaranteed, puncture positioning errors of complex cases are further reduced, whether angle or depth deviation occurs in a puncture path or not is judged in real time by arranging a dynamic navigation end, a compensation path can be planned in real time through a blood vessel elastic characteristic matrix, and it is guaranteed that the angle errors are reduced when a needle body enters a blood vessel.

Apparatus and methods for an implant are provided. The implant may have a constrained configuration and a relaxed configuration. The implant may include a strut having an end that may be captured by a hub and may define a reference angle in the relaxed configuration. The implant may include a swivel body that may engage a shaft of a delivery cable and may be rotated through the reference angle. The apparatus may include a pusher catheter to push the implant. The delivery cable may engage the implant. The apparatus may include gauge handle that may include a force gauge to indicate the presence of a force acting on the implant. The apparatus may include a bushing that may be fixed to an end of a pusher catheter. The bushing may move along a delivery catheter lumen and may guide the implant to a keyed position at the bushing.

Systems and methods of the invention generally relate to prolonging viability of bodily tissue, especially lung tissue, through the use of an expandable accumulator to maintain a constant pressure within the lumen of the organ even during external pressure fluctuations due to, for example, flight. Systems and methods may include prolonging donor organ viability in storage through the use of an organ container that mimics the geometry and orientation of the organ in vivo.

Sanitary tissue products of the present disclosure may comprise at least about 70% short fibers and / or having a weight weighted mean fiber length of less than about 1.4, and may have one or a combination of premium performance parameter(s). One or more of said sanitary tissue products may form part of an array of sanitary tissue products.

Catheter devices for treating occlusions in body lumen are described herein. The catheter devices may include a tubular body having a distal end, an distal portion elastically connected to the distal end of the tubular body, an impactor connected to the distal portion and separated by a space from the distal end of the tubular body, a distal shock wave emitter located adjacent to the space and connected to a power source, and an enclosure at least partially surrounding each of the distal end of the tubular body, the elastic distal portion, the impactor, and the distal shock wave emitter. The impactor may be configured to move in response to shock waves generated from the distal shock wave emitter, such that a length of the space in the proximal-distal direction increases by between 0.05 mm and 0.6 mm.

In some embodiments, a system can include a fluid delivery assembly and a motor drive assembly. The fluid delivery assembly is configured to be releasably mechanically and, optionally, electrically coupled to the motor drive assembly. When the fluid delivery assembly is releasably coupled to the motor drive assembly, the motor drive assembly can control delivery of fluid from the fluid delivery assembly (e.g., to a patient). For example, the motor drive assembly can be releasably coupled to the fluid delivery assembly to control delivery of fluid from the fluid delivery assembly to provide continuous (e.g., non-pulsatile) fluid flow from the fluid delivery assembly.

Systems and methods of the invention generally relate to prolonging viability of bodily tissue, especially an organ such as a lung, by adjusting pressure as needed to maintain a constant pressure within the organ even during external pressure fluctuations due, for example, to transportation of the organ in an airplane. Gas passing into and out of the organ may be conditioned to prolong tissue viability.

A transport container and methods for preserving a heart at a hypothermic temperature. The transport container can maintain the heart at a temperature of 6-8° C. for improved results after transplantation. The preservation of the heart within this range can improve transplantation outcomes.

Apparatus and methods for an implant are provided. The implant may have a constrained configuration and a relaxed configuration. The implant may include a strut having an end that may be captured by a hub and may define a reference angle in the relaxed configuration. The implant may include a swivel body that may engage a shaft of a delivery cable and may be rotated through the reference angle. The apparatus may include a pusher catheter to push the implant. The delivery cable may engage the implant. The apparatus may include gauge handle that may include a force gauge to indicate the presence of a force acting on the implant. The apparatus may include a bushing that may be fixed to an end of a pusher catheter. The bushing may move along a delivery catheter lumen and may guide the implant to a keyed position at the bushing.

Systems and methods of the invention generally relate to prolonging viability of bodily tissue, especially lung tissue, through the use of an expandable accumulator to maintain a constant pressure within the lumen of the organ even during external pressure fluctuations due to, for example, flight. Systems and methods may include prolonging donor organ viability in storage through the use of an organ container that mimics the geometry and orientation of the organ in vivo.

The invention discloses a brain-computer hybrid intelligent closed-loop swallowing rehabilitation system for treating dysphagia after stroke, and relates to the field of artificial intelligence medical instruments. The system is composed of a plurality of key modules: an intelligent swallowing brain-computer interface module for accurately identifying a swallowing intention through multi-modal physiological signal acquisition and processing; the intelligent swallowing functional electrical stimulation module is used for finely regulating and controlling stimulation parameters according to the condition of the patient; the AI auxiliary online integrated module is used for realizing non-invasive brain-controlled swallowing and high-precision AI regulation and control; the closed-loop intelligent feedback regulation and control module is used for real-time monitoring, early warning and self-adaptive optimization of electrical stimulation; the cloud platform remote monitoring and data storage module supports remote diagnosis and treatment of doctors; and the man-machine interaction interface display and printing module optimizes doctor-patient interaction. According to the system, a brain-computer interface and FES are combined, a personalized, safe and efficient rehabilitation scheme is provided for a patient based on data driving and an artificial intelligence algorithm, swallowing function recovery can be accelerated, complications are reduced, and the system has great clinical and social values.