The invention relates to the technical field of hot chamber dismounting tools, and provides a hot chamber dismounting device and method for an active area of an
irradiation device. The device comprises a fixed base used for placing an active area, a first limiting piece used for limiting the active area from moving upwards, a
wrench used for screwing a sunk screw, a cross-shaped gripper used for grabbing a hanging connector, a second limiting piece used for limiting a
single sample module from moving upwards, and a grabbing piece used for grabbing a positioning pressing plate. The single-hook tool is used for grabbing a separation blade; and the double-hook tool is used for grabbing a sample plate. According to the invention, each dismounting tool is combined with the
manipulator, each part in the active area can be dismounted, and in addition, the pins at the bottom of the active area are inserted into the positioning holes in the fixed base, so that the active area can be prevented from toppling over in the operation process; meanwhile, the first limiting piece can limit the upward movement of the active area, and the second limiting piece can limit the upward movement of a
single sample module, so that other parts are prevented from being taken away when a single tool is matched with a
manipulator to disassemble a certain part, and the operation is more convenient.