30results about How to "Less invasive" patented technology

The invention provides a human-computer interaction method, electronic equipment and a storage medium, relates to the technical field of human-computer interaction, and is used for reducing user operation steps and improving user experience. The method comprises the following steps: in response to detection of a selection operation of a user on data on a current display screen, obtaining data content selected by the user, and receiving an operation instruction input by the user; calling the first large language model to perform processing operation indicated by the operation instruction on the data content to obtain a processing result of the data content; and displaying the processing result on the current display screen.

The invention is applicable to the technical field of clinical examination and auxiliary diagnosis, and provides an extreme behavior risk auxiliary diagnosis biomarker combination, a kit and a detection method, the biomarker combination is composed of IL-4, IL-12 and IFN gamma, and the extreme behavior risk can be objectively identified by detecting the expression level of the combination in peripheral blood of a subject. The matched kit comprises specific antibodies aiming at the three markers, a standard substance, a buffer solution and other reagents, and according to the standardized detection method, through peripheral blood sample treatment, incubation, fluorescent staining, flow detection and result analysis, precise evaluation is achieved in combination with a clear judgment threshold value. According to the method, the defect that suicide risk assessment depends on a subjective scale and doctor experience in the prior art is overcome, the operation is convenient, the result is objective, the combined detection AUC of the suicide risk assessment, the subjective scale and the doctor experience can reach 0.726, a reliable extreme behavior risk auxiliary diagnosis means is provided for clinic, and the method is particularly suitable for risk identification of depression patients and has important clinical application value and conversion prospect.

This invention relates to the fields of brachytherapy and radiosensitization, specifically providing a... 125 I-nano implantable particles, their preparation methods, and applications. 125 The 1-nanometer implanted particles have a core-shell structure, consisting of a particle core and particles adsorbed on the outer surface of the particle core. 125 I and the particles encapsulated in the nucleus and 125 The outer shell of the I-type photosensitizer is a covalent organic framework. This invention... 125 The core of the I-nanometer implanted particle is used to enhance the energy deposition of gamma rays and X-rays, generating more hydroxyl radicals; the shell containing a type I photosensitizer is used to absorb the energy of Auger electrons and internal conversion electrons and excite the photosensitizer to generate singlet oxygen, effectively improving the response to... 125 The efficiency of I decay energy utilization. 125 I-nano implanted particles, combined with internal radiation therapy and radiodynamic therapy, destroy tumor cell DNA and cell membranes, enhance tumor killing and induce immunogenic cell death, thereby activating anti-tumor immunity and inducing remote effects.

The invention relates to the technical field of keloid resection, and discloses a minimally invasive surgery device for keloid core resection, which comprises a body, and further comprises an outer sleeve fixedly connected to the front end of the body, the outer sleeve is of a slender hollow structure and is used for being inserted into keloid tissues through a skin tiny incision; the inner cutting tube is coaxially arranged in the outer sleeve and can rotate relative to the outer sleeve, and an annular cutting edge used for cutting keloid fibrous tissue is formed at the far end of the inner cutting tube; according to the minimally invasive surgery device for keloid core excision, the outer sleeve and the inner excision tube are coaxially arranged, and the annular cutting edge used for cutting keloid fibrous tissue is formed at the far end of the inner excision tube, so that the device can enter the keloid through a tiny incision of the skin; on the premise of reducing skin wounds, effective treatment of keloid core tissues is realized, and improvement of postoperative healing effect and appearance recovery are facilitated.

The utility model discloses an intramedullary needle for treating fracture and convenient to hold, which is provided with a treatment section and a holding section for operating and holding, and a positioning structure for holding and positioning is further arranged on the holding section. The intramedullary needle conforms to tubular bone biological fixation, the treatment section can be effectively prevented from rotating in the surgical treatment operation process through the holding section, the penetration depth and path of the treatment section can be further accurately controlled, the treatment accuracy is improved, and the treatment duration is shortened. When the intramedullary needle is used in the treatment process of metacarpal bone fracture, further damage to fracture local hematoma and periosteum can be avoided through closed reduction, blood supply of sclerotin is protected, and fracture healing is facilitated. The intramedullary needle is small in trauma, small in wound scar and beneficial to attractiveness; intramedullary fixation retains the minimally invasive characteristic of kirschner wire fixation, and the fixing effect is more stable and lasting than that of a kirschner wire, and the articular surface is not damaged.

The application discloses a data security protection method and system of a WEB information system; the method comprises the following steps: a front end adoptsWEBPACK to pack and introduce a code confusion module; the front end encrypts and sends request data; a back end verifies, decrypts, forwards the request data, and receives response data returned by an actual business processing program; the back end returns the response data to the front end after encryption; and the front end intercepts a response receiving event of an HTTP / HTTPS client, decrypts the received encrypted response data by using a dynamic key, and obtains actual response data. The application has extremely high security and extremely low modification cost for an original system, and a back end business program does not need to be modified.

The application relates to a method and system for dynamically optimizing CPU scheduling based on thread affinity, and belongs to the technical field of computer operating system performance optimization. The system constructs an affinity thread graph of a target thread in real time through eBPF, analyzes the CPU resident distribution of the affinity thread, integrates the affinity information into CPU selection, task queuing and dispatching logic, realizes the same core / NUMA node scheduling of the target thread and the affinity thread, reduces the cross-core overhead, and improves the execution efficiency of the target thread.

The utility model provides a kind of nail bed biopsy assembly, including main body, main body includes outer tube and inner core, outer tube includes outer tube head, and the lateral wall of outer tube head is equipped with outside hole, outside hole is towards the nail bed;Inner core includes inner core head, and inner core head includes inner core inner arc surface and inner core outer arc surface, the edge of inner core inner arc surface and the edge of inner core outer arc surface are connected, to form cutting part respectively at the two side edges of inner core inner arc surface and inner core outer arc surface, the distance between the edge of inner core inner arc surface and the edge of inner core outer arc surface gradually decreases from rear side to front side, and tissue accommodating part is formed on inner core inner arc surface;Inner core is rotationally arranged in outer tube, and inner core head is oppositely arranged with outer tube head, when inner core rotates relative to outer tube, the cutting part of inner core head is rotated and cut to nail bed through outside hole, and cut nail bed tissue is contained in tissue accommodating part, it is convenient and fast to use, small trauma and fast recovery.

The invention provides a Parkinson's disease rapid RT-QuIC diagnostic kit based on A30P mutant alpha-synuclein, and belongs to the technical field of detection kits. The specific A30P mutant protein is used as a reaction substrate, and rapid and high-sensitivity amplification detection can be carried out on trace misfolded alpha-synuclein in a skin sample through an optimized RT-QuIC system. The kit has the characteristics of short detection period and convenience in operation, provides a new tool for molecular diagnosis of Parkinson's disease, is suitable for definite diagnosis of clinical PD suspected cases, and can also be used for screening high-risk groups. The kit has the advantages of mature preparation process, easily available raw materials, easiness in industrial production and large-scale popularization, and important clinical application value.

The utility model relates to medical instrument technical field in general, and more particularly to a kind of postoperative minimally invasive subcutaneous continuous drainage device, including puncture needle, drainage sheath, three-way valve, drainage tube and negative pressure drainage bottle, three-way valve includes first port, second port and third port, first port and second port coaxial arrangement, drainage sheath is connected with first port, puncture needle is inserted by second port and passes out from drainage sheath, negative pressure drainage bottle is connected with third port by drainage tube.The application is pierced by puncture needle, so that drainage sheath enters the wound part in body together, after reaching the wound part, the puncture needle is extracted from second port, since the puncture needle fills the drainage sheath when puncturing, the tissue debris can be avoided to block the drainage sheath, after extracting the puncture needle and leaving the drainage sheath, the drainage sheath can establish good suction passage, and simultaneously switch three-way valve, so that pus and blood water directly enter negative pressure drainage bottle along drainage tube from third port, avoid the leakage of drainage fluid caused by complicated disassembly and assembly.

The application relates to the technical field of wireless screen projection, in particular to an Airplay directional screen projection method and device, which are applied to a proxy server configured with double network cards, the proxy server is arranged between a guest network and a screen projection device network and respectively accesses the two networks; after an mDNS query packet of a user mobile phone terminal is acquired through a guest network card, a simplified mDNS response packet is replied to induce the mobile phone terminal to send a unicast query packet; the unicast query packet is forwarded to a screen projection device network multicast address, only a multicast response packet of a screen projection service bound with the mobile phone terminal is received; a service address in the response packet is modified into a guest network card IP and is fed back to the mobile phone terminal, and a NAT network channel is simultaneously established. The application solves the screen projection service discovery difficulty and the screen projection service discovery difficulty caused by VLAN isolation in a hotel and the like scene, does not need to change an existing network topology, realizes directional screen projection, the screen projection service can be flexibly arranged, adapts to different scene requirements, and has high connection stability.

The invention belongs to the technical field of computers, and particularly relates to a geographic grid code perturbation method and system for a Redis cluster, and the method comprises the steps: obtaining an original geographic grid code corresponding to a target geographic position, and enabling the original geographic grid code to have spatial locality; inputting the original geographic grid code into a preset disturbance function to generate a disturbed grid code; according to the disturbed grid code, generating a key for accessing a Redis cluster; and performing data access operation in the Redis cluster by using the key. The original geographic grid codes are transformed through a perturbation function, and the spatial locality of coded values is fundamentally broken. Therefore, the cache keys corresponding to the data originally gathered in the same geographic area can be uniformly dispersed into different slots of the Redis cluster after being disturbed, so that the access pressure is allocated to a plurality of nodes, and overload of a single node is avoided.

The utility model relates to a kind of supporting laryngeal mirrors, laryngeal mirror main part is tubular, with proximal end and distal end, including laryngeal mirror main body, lever fixer;The distal end of the laryngeal mirror main body is double-lip structure, and there is the front lip of being closer to handle and the back lip of being farther away from handle;The lever fixer has two lever limiting structures coaxially arranged, which can fix the lever, and the inner side fixing part and the outer side fixing part can be fixedly connected with the edge part of the proximal end of the laryngeal mirror main body, wherein the inner side fixing part is fixed in the tube of the laryngeal mirror main body, and the outer side fixing part is fixed outside the tube of the laryngeal mirror main body.The laryngeal mirror can expose patients with difficult anterior commissure exposure, so that surgery can be performed.

The utility model belongs to drainage tube technical field, specifically chest cavity multi -position drainage tube, including hose one, the inside lower surface left and right sides of hose one are all set up and have the through -going hole of through -going type, two the through -going hole between penetration has hose two, the right end of hose two penetrates hose one, the left end of hose two is set up as the connecting end, the right end of hose two curved end sets into the insertion end, the right end of hose two curved place sets up and has a plurality of through -going type through -hole, the utility model discloses buffer assembly can when hose one and hose two are subjected to the drawing to buffer, and when hose one and hose two are subjected to the drawing to drive the sliding of buffer block in the inner groove, and when the sliding of buffer block is guided through the sliding connection of guide rod and guide groove, then buffer block is extruded and is triggered to buffer the extrusion received, and make hose one and hose two are subjected to the drawing to get the buffer, and avoid the injury of patient after the drawing of hose one hose two.

The application discloses a log collection method and device, electronic equipment and medium, and relates to the technical field of computers.The method comprises the following steps: scanning log files under a parent directory, and determining log files to be collected in the parent directory, wherein the parent directory is used for storing a log directory, the log directory is used for storing log files, and the log directory is named based on a container identifier; and collecting the content in the log files to be collected.The method stores the log directory named based on the container identifier in the parent directory, so that the log files are stored in the same parent directory, and in the case that a new log directory is generated due to container redeployment, the newly generated log directory can be accurately and quickly located, the newly generated log file is quickly located, the coupling between the container and the log collection is reduced, and the log collection tool or the log collection code does not need to be upgraded; and the method does not need to introduce a third-party framework, has low invasiveness, and has high timeliness.

The present application belongs to the field of human-computer interaction, and relates to a human-computer trust real-time measurement method and system based on heart rate variability. The present application performs principal component analysis on multiple time domain, frequency domain and nonlinear heart rate variability characteristics, and constructs a human-computer trust real-time measurement model on this basis; in application, user electrocardio signals are collected, heart rate variability characteristics are extracted from the user electrocardio signals; the heart rate variability characteristics are input into a load matrix, and a principal component matrix is calculated according to the load matrix; the principal component matrix is input into the human-computer trust real-time measurement model, and human-computer trust real-time measurement results are obtained. The present application is based on user heart rate variability characteristics, can realize real-time measurement of human-computer trust, and overcomes defects in measurement cost, accuracy, stability and anti-interference.

The application discloses a kind of diabetic foot functional shoes, and the diabetic foot functional shoes include: data service module is used to transmit massage information to control module;Control module is used to send massage opening signal;Massage module is used to massage the sole of user;Data service module is used to send detection signal;Pressure detection module is used to detect the sole pressure of user in real time, and transmission to data service module;Data service module is used to store the sole pressure of user, and the ulcer position of user foot is predicted, and feedback to user;Data service module is also used to set ultrasonic disinfection mode, and convert into ultrasonic disinfection information transmission to control module;Control module is used to send disinfection opening signal to ultrasonic disinfection module;Ultrasonic disinfection module is used to disinfect in shoe.This application reduces the probability of foot trauma, and can prevent ulcer to a certain extent, can avoid the condition of infection after user foot breakage.

The present application relates to a kind of Alzheimer's disease detection marker and its application, by detecting the p-Tau217 of exosome (plasma or urine source total exosome or nerve source specificity exosome), realize the noninvasive detection diagnosis of Alzheimer's disease.The kit of the present application has the advantages of noninvasive detection, high sensitivity, strong specificity, does not depend on large equipment, etc., solves the existing Alzheimer's disease detection kit sample acquisition invasiveness, low accuracy, large equipment dependence and poor precision etc.Problems, suitable for the needs of clinical large sample detection, can be used for early diagnosis of Alzheimer's disease, disease progression monitoring and efficacy evaluation etc..

This invention discloses a portable endoscope comprising a handheld mechanism, a detection mechanism mounted on the handheld mechanism, and a drive mechanism. The detection mechanism includes an insertion tube and a camera, configured to bend and extend into an internal cavity. The camera is mounted at the end of the insertion tube and is suitable for acquiring image information. The drive mechanism includes two pairs of drive wires, the ends of which are respectively connected to four equal parts of the end of the insertion tube. A positioning plate is mounted on the handheld mechanism, through which both pairs of drive wires pass. Multiple elastic tubes are respectively sleeved around each drive wire and installed between the positioning plate and the end of the insertion tube to tension the insertion tube. The drive assembly mounted on the handheld mechanism is configured to lengthen or shorten the lengths of the two pairs of drive wires located between the positioning plate and the end of the insertion tube, with opposite length changes in the radial direction between the two opposing drive wires, causing the end of the insertion tube to bend, facilitating camera position adjustment, portability, and wide applicability.

The utility model provides a bendable nerve ventricle endoscope, and relates to the technical field of endoscopes. A bendable nerve ventricle endoscope comprises a handle, the handle is provided with an insertion tube, a bent snake bone is arranged at the end, away from the handle, of the insertion tube, a tip is arranged at the end, away from the insertion tube, of the bent snake bone, and a camera is arranged at the tip; the bent snake bone is hollow, two pull wires are oppositely connected to the inner side wall of the front end of the bent snake bone, the pull wires penetrate through the insertion tube and extend into the handle, and the handle is provided with a traction assembly used for pulling the pull wires. By the adoption of the cranial nerve endoscope, the problems that a traditional cranial nerve operation is large in trauma and large in operation difficulty can be solved, the endoscope is simple in structure, convenient to use, small in trauma and capable of being bent easily, lesions which cannot be displayed by a hard endoscope can be observed, the operation can be carried out at the same time, a safer and more reliable technical means is provided for the cranial nerve operation, and popularization and application are facilitated. The operation quality is improved, and the operation complications are reduced.

This invention belongs to the field of data processing technology, specifically relating to a Java runtime dynamic data mapping method, system, and computer device based on Web configuration and bytecode enhancement. The method includes the following steps: S1, receiving user-defined mapping rules between source and target POJO objects via a Web interface; S2, in the Java Virtual Machine runtime environment, when the classes of the source and target POJO objects are loaded, enhancing the bytecode of the classes by statically injecting a metadata cache structure into the bytecode. The metadata cache structure includes field type information and corresponding field access method handles; S3, resolving the source and target field paths according to the mapping rules to form an access chain, and based on the field access method handles, retrieving values ​​from the source POJO object field by field along the access chain and assigning them to the target POJO object to complete the data mapping. This method supports dynamic configuration on the Web client and achieves near-handwritten code performance at the Java runtime.

The invention discloses a flushing and drainage integrated peritoneal drainage tube with a rapid butt joint function, and relates to the technical field of medical instruments, the flushing and drainage integrated peritoneal drainage tube comprises an insertion tube, the far end of the insertion tube is plugged into a circular arc shape, the near end of the insertion tube is communicated with one end of a drainage section, and the other end of the drainage section is communicated with a connector assembly; the peripheral surface of the drainage section is sleeved with a flushing fluid distribution unit, and the flushing fluid distribution unit is communicated with the insertion tube; a flushing opening is formed in the far end of the insertion tube, and drainage openings are formed in the outer side wall of the insertion tube at equal intervals. The flushing opening is communicated with the flushing fluid distribution unit, and the drainage opening is communicated with the drainage section. According to the flushing and drainage integrated peritoneal drainage tube with the rapid butt joint function, flushing and drainage pipelines are integrated in a body mode, extra puncture catheterization is not needed, wounds of a patient are reduced, cooperation of the precise targeting effect of flushing fluid and rapid discharge of secretions is achieved, the operation process is simple, and the work intensity of medical workers is greatly reduced.

The utility model relates to an extension device, which comprises a catheter main body, which is designed to be capable of being inserted into two organs of a human or mammal and having a passage connected between the two organs, and has a guide part, an extension part and a perfusion part, the extension part comprises an extension sac, the extension sac is designed to be capable of expanding the passage between the two organs, and the extension device further comprises a limiting element, which is capable of limiting or controlling the size of the expansion of the extension sac to keep it within a limited size, so that the rupture of the extension sac under high pressure can be reduced, the expansion size of the pipeline is consistent, and the accuracy and precision of operation are increased.

The present application relates to the technical field of biological medicine, disclose a kind of new use of human-derived miR-335-3p and the method for regulating target gene IL-16 expression, its new use is to inhibit yellow ligament cell fibrosis, and hsa-miR-335-3p can be targeted to bind IL-16 mRNA 3'UTR, the 8mer binding site of human-derived miR-335-3p and IL-16 mRNA 3'UTR exists, located at 775-782 of 3'UTR, to inhibit the expression of IL-16 gene, and interfere with the function of IL-16 gene to promote yellow ligament hypertrophy, it has wide application prospect on the drug related to lumbar yellow ligament hypertrophy, based on the present application can be made to treat or prevent the disease related to lumbar yellow ligament hypertrophy drug or detection kit.

This invention belongs to the field of medical device technology, and particularly relates to a multifunctional prostate surgery diagnostic and treatment device. The device's electronic endoscope includes a front section assembly, a middle section assembly, and a rear section assembly connected sequentially from front to back. The first front end assembly of the enucleation module is detachably connected to the rear section assembly within the electronic endoscope. The working rod of the rotary cutting module can be inserted from the rear section assembly, sequentially extending into the middle section assembly and the front section assembly, and extending out from the front section assembly; the working rod is axially movable within the electronic endoscope. The second front end assembly of the laser module is detachably connected to the rear section assembly within the electronic endoscope. Therefore, this device can perform multiple surgical operations such as enucleation, rotary cutting, and laser vaporization / cutting by quickly replacing only the enucleation module, rotary cutting module, and laser module at the rear of the electronic endoscope, without needing to replace the entire electronic endoscope. This greatly reduces the operational difficulty during diagnosis and treatment, achieving "one endoscope for multiple uses," integrating multiple functions, and simplifying the operation process.

The invention provides an Alzheimer's disease biomarker and a screening method thereof. The Alzheimer's disease biomarker is a CD44 gene or a protein coded by the CD44 gene. The screening method of the Alzheimer's disease biomarker comprises the following steps: screening differential expression genes of AD patients through a GEO database, obtaining differentially expressed ferroptosis related genes, carrying out protein interaction network analysis on the differential expression genes of the AD patients related to ferroptosis, carrying out Mendel randomization through machine learning, and screening out the differential expression genes of the AD patients related to ferroptosis; and carrying out human plasma RT-qPCR verification on the randomization result, and selecting a gene which is different from the control group in expression level in the RT-qPCR verification as the Alzheimer's disease biomarker. The CD44 is used as the Alzheimer's disease biomarker, the prediction effect is excellent, a new clue is provided for diagnosis and treatment of AD, and a foundation is laid for revealing complex pathogenesis and developing more effective intervention measures.

The application relates to an FTP unstructured file transmission breakpoint continuation implementation method and device based on DataX. The method comprises the following steps: integrating a progress tracking module into a DataX Writer, creating a transmission progress metadata file (TPMF) containing information such as the number of uploaded bytes and the state for each file and dynamically updating; deploying an independent process monitor to monitor task interruption and trigger progress persistence to the TPFM; a user selects a file through an independent FTP continuation scheduler, reads the TPFM and the server-side target file size to determine the breakpoint, calls an FTP REST command to continue from the breakpoint, updates the state after completion, and the like. The method realizes accurate progress recording, active saving in abnormal interruption and user-controllable continuation, avoids redundant retransmission, improves transmission efficiency and resource utilization, enhances data synchronization robustness and reduces operation and maintenance complexity. The method has small invasiveness to the DataX core, is strong in universality and is suitable for high-reliability synchronization scenes of large-scale unstructured files.

The invention discloses a vagus nerve double-targeting delivery carrier as well as a preparation method and application thereof. According to the vagus nerve double-targeting delivery carrier, the surface of a nano carrier is simultaneously modified with a first targeting ligand capable of being combined with a nicotinic acetylcholine receptor on the surface of vagus nerve cells and a second targeting ligand capable of being specifically combined with a transient receptor potential channel. The enrichment efficiency and the spatial selectivity of the photoresponse nano-carrier in the vagus nerve area are effectively improved through a targeting delivery strategy of lymphatic path guidance and double receptor molecule recognition, the specific targeting of the photoresponse nano-carrier to the vagus nerve is enhanced, and in the follow-up NIR light irradiation process, the photoresponse nano-carrier has a good application prospect. Effective activation of the vagus nerve can be realized under lower optical power density, non-specific stimulation to surrounding non-target tissues is remarkably reduced, and safety and accuracy of light regulation of the vagus nerve are improved.

The application discloses a service processing method, comprising: starting a load monitor when receiving a service processing instruction; collecting current resource utilization by using the load monitor; if the current resource utilization exceeds a preset threshold, skipping a service thread provided with an annotation identifier and executing a service thread not provided with the annotation identifier; and if the current resource utilization does not exceed the preset threshold, executing all service threads. By using the technical scheme provided by the application, system resources can be flexibly allocated when system load pressure is high, thereby ensuring normal operation of services. The application also discloses a service processing device, an electronic device and a computer readable storage medium, which also have the above technical effects.