29 results about "Fibrous tissue" patented technology

A pressure-sensitive stacking structure for a sports training device of the present invention that is able to detect a pressure with which a player grips a grip portion may include: a conductive layer that is pressure-sensitive; a circuit layer disposed to face the conductive layer and having a plurality of conductive patterns; and a separating layer disposed between the conductive layer and the circuit layer and formed of a fibrous tissue including a plurality of fibers, wherein, when a pressure is generated, the conductive layer and the circuit layer may come into contact, and the pressure may be detected.

The invention discloses an operation method for splitting an oral implant bone, which comprises the following steps of: preparing an ultrathin bone sheet of which the buccal side is less than 1mm, reserving physiological connection between periosteum and the bone sheet, and constructing a periosteum bone flap. The periosteum flap is of a natural barrier membrane structure, and integrates the function of a bone sheet rigid support and the semi-permeable membrane characteristic of the periosteum. The buccal ultrathin bone sheet is connected with the basal bone, is a rigid support structure, supports an osteogenesis space, and can provide bone marrow stroma cells to participate in bone defect repair. Physiological attachment of periosteum is not only a blood supply source of an inner side bone sheet, but also exerts the characteristics of a semi-permeable membrane, replaces an artificial barrier membrane to stop fiber tissue from growing in, and follows the PASS principle of the GBR technology, so that the operation risk is reduced, the use of the artificial barrier membrane is reduced, the adaptation disease of bone splitting is widened, the absorption of buccal side bones is reduced, and the bone splitting effect is improved. And the clinical effect of bone defect repair is improved.

The invention discloses bioactive porous high-density polyethylene foam and a preparation method thereof, and belongs to the technical field of medical implant materials. The preparation method comprises the following steps: (1) mixing high-density polyethylene powder and template particles, carrying out hot press molding, ultrasonically removing the template particles in a solvent, and finally washing and drying to obtain porous high-density polyethylene foam; and (2) sequentially soaking and modifying the porous high-density polyethylene foam in a hydrophilic improver, a biological active agent and an antibacterial agent, and drying to obtain the porous high-density polyethylene foam. The preparation method disclosed by the invention is simple, and the obtained bioactive high-density polyethylene foam with the porous structure has good biological activity, hydrophilicity and excellent mechanical properties, is beneficial to cell adhesion, material exchange, fibroblast ingrowth and angiogenesis, can be used as a craniomaxillofacial non-bearing area bone defect repair material, and has wide application prospects. And the method has a huge practical application prospect.

Provided are microRNA from a Rhodiola root and uses thereof in the prevention and / or the treatment of a fibroplasia medical sign and / or syndrome.

The utility model relates to a multifunctional warm mattress. The multifunctional warm mattress comprises a mattress body and a controller, the mattress body is provided with a heating wire and a red light LED, and the controller is connected with the electrode plates through wires; wherein a main control board and a power supply module are arranged in the controller, one path of external power supply is connected with the heating wire through a temperature control circuit and a temperature control switch on the main control board, and the other path of external power supply is connected with the MCU microprocessor through the power supply module; one output end of the MCU microprocessor is connected with a red light LED through a lamp control circuit; the other output end of the MCU microprocessor is connected with an electrode plate through an intermediate frequency signal generator, a modulator and a current controller; and the signal input end of the MCU microprocessor is connected with the temperature sensor. According to the multifunctional warm mattress, on the basis of the warm effect, the red light near-illumination and electrical stimulation functions are expanded, so that the multifunctional warm mattress has the effects of promoting fiber tissue repair and relieving local pain, and meanwhile, the hidden danger of product overheating is eliminated through double protection of feedback temperature control adjustment and overtemperature hard breakage.

The present disclosure relates to systems, devices, and methods for subcutaneously cutting and treating tissue and cellulite with non-invasive acoustic waves. Embodiments of the present disclosure refer to systems, devices, and methods that use unfocused or planar, non-cavitating acoustic waves to induce physical effects in tissue such as dermis, fat, muscle, bone, blood vessels, liver tissue, etc. The physical effects include disruption of the fibrous extracellular matrix of the target tissue. Embodiments of the present disclosure include the application of multiple rapid acoustic pulses (e.g., shockwaves) to cause the breakdown of the fibrous extracellular matrix to reduce the appearance of cellulite or scarring in the treated area. Such unfocused or planar, non-cavitating acoustic waves can induce tissue responses such as reduced fibrosis, induction of angiogenesis or lymphangiogenesis, etc.

This application proposes a traditional Chinese medicine composition and preparation method for treating atrophic gastritis of spleen deficiency and blood stasis type, involving the field of traditional Chinese medicine. It utilizes Bupleurum chinense, stir-fried Paeonia lactiflora, Citrus reticulata peel, Pinellia ternata, Codonopsis pilosula, Poria cocos, stir-fried Atractylodes macrocephala, prepared Glycyrrhiza uralensis, Agrimonia pilosa, and Curcuma zedoaria, and establishes a water extraction and decoction preparation process. A rat model of precancerous gastric lesions was established using MNNG combined with multiple factors. Normal control group, model group, folic acid group, and traditional Chinese medicine group were set up to observe the morphological and pathological changes of the gastric mucosa. The results showed that the traditional Chinese medicine composition can reduce gastric mucosal atrophy, inflammatory cell infiltration, and fibrous tissue hyperplasia, alleviate intestinal metaplasia, downregulate the expression of AKT and mTOR proteins in the gastric mucosa, and inhibit abnormal mucosal proliferation. Its effect is superior to that of folic acid, providing experimental evidence for clinical treatment.

The invention relates to the technical field of keloid resection, and discloses a minimally invasive surgery device for keloid core resection, which comprises a body, and further comprises an outer sleeve fixedly connected to the front end of the body, the outer sleeve is of a slender hollow structure and is used for being inserted into keloid tissues through a skin tiny incision; the inner cutting tube is coaxially arranged in the outer sleeve and can rotate relative to the outer sleeve, and an annular cutting edge used for cutting keloid fibrous tissue is formed at the far end of the inner cutting tube; according to the minimally invasive surgery device for keloid core excision, the outer sleeve and the inner excision tube are coaxially arranged, and the annular cutting edge used for cutting keloid fibrous tissue is formed at the far end of the inner excision tube, so that the device can enter the keloid through a tiny incision of the skin; on the premise of reducing skin wounds, effective treatment of keloid core tissues is realized, and improvement of postoperative healing effect and appearance recovery are facilitated.

The application provides a traditional Chinese medicine external application method for reducing the risk of fistula fibrosis in dialysis patients, relates to the technical field of clinical application of traditional Chinese medicine, is suitable for the prevention of autologous arteriovenous fistula fibrosis of maintenance hemodialysis patients, can effectively reduce the incidence of complications such as fistula peripheral tissue fibrosis and vascular stenosis, and prolongs the service life of the fistula. The drug stability and skin permeability are improved through optimization of adjuvants, and based on the grouping intervention of maintenance hemodialysis patients, the fistula blood flow and fibrosis improvement are evaluated in combination with color Doppler ultrasound. The application takes the principles of promoting blood circulation to remove blood stasis, dredging collaterals and resolving knots, and detoxification and swelling reduction as the therapeutic principles, prepares a fistula protection ointment by screening and optimizing a traditional Chinese medicine formula, realizes the effects of improving local microcirculation of the fistula, inhibiting fibrous tissue proliferation and reducing inflammatory reactions through external application intervention, thereby reducing the incidence of fistula fibrosis and related complications, prolonging the fistula patency time, simultaneously reducing the treatment cost, and improving the patient tolerance and life quality.

According to the lung fibrous tissue removing device, starting from the source, abnormal fibrous grids in a pleural cavity are safely and effectively broken, ablated or cut off in a physical or energy mode, all separated small rooms are broken through, and a plurality of independent areas are fused into a whole. Therefore, all effusion in the thoracic cavity can be thoroughly drained only through one-time puncture or a few times of puncture. The operation time can be remarkably shortened, the pain of a patient can be relieved, lung trauma and various complications caused by multiple times of puncture can be fundamentally avoided, the treatment effect and safety of pleural effusion, especially complex atrial effusion, are greatly improved, and important clinical value and social significance are achieved.

The invention discloses a personalized implantation structure and method for improving insufficient chin anterior movement in a chin shaping surgery, the personalized implantation structure comprises an implant and a chin anterior movement osteotomy matched with the implant, and the implant is fixed on the chin anterior movement osteotomy. Compared with the prior art, osteotomy forward movement and the implant are combined together to be applied to the chin forming operation, and when the chin bone mass of a patient is insufficient, supplementation can be conducted through the implant. Compared with an autogenous bone or an artificial bone for transplantation, the implant does not need to face the problems of absorption, rejection and the like, and the risk of a secondary operation cannot be increased; meanwhile, compared with the mode that the prosthesis is completely adopted for implantation, the burden of mandibular fibrous tissue can be relieved, and the risk of implant displacement can also be reduced.

The invention discloses an ascites drainage control device, and belongs to the technical field of medical instruments, the ascites drainage control device comprises a control assembly, the front end of the control assembly is connected with a first drainage tube, the rear end of the control assembly is connected with a second drainage tube, the first drainage tube is used for being placed in an abdominal cavity, and the second drainage tube is used for being connected with a drainage ball. Complications such as abrupt pressure drop of the abdominal cavity, hypotension and hepatic encephalopathy caused by out-of-control flow velocity of traditional equipment are effectively avoided through the flow velocity adjusting mechanism; through magnetic positioning and fixing buckle design, it is guaranteed that the adjusting state is stable, the pipeline is fixed reliably, and the risks of drainage tube disengagement, displacement, folding, winding and infection are reduced; two-way dredging of the pipeline can be completed without additional instruments, the problem of blood clot and fiber tissue blockage is solved quickly, and drainage interruption is avoided.

A spinal implant is provided that is configured to receive a fill material is provided that includes a wall that defines an interior chamber. The wall has an interior side, an exterior side, and a wall thickness that extends between the interior side and the exterior side. The wall has a porosity that permits fluid passage through the wall thickness and permits blood vessels and fibrous tissue to extend through the wall thickness. The interior chamber has a first chamber segment and a second chamber segment. In the first chamber segment, the wall has a first wall configuration. In the second chamber segment, the wall has a second wall configuration. The first chamber segment has a first volumetric expansion ratio and the second chamber segment has a second volumetric expansion ratio. The second volumetric expansion ratio is greater than the first volumetric expansion ratio.

Modulation of foreign body responses in living tissue, and more particularly, devices and related methods for light-based modulation of foreign body responses in living tissue are disclosed. Light sources are disclosed that provide light with characteristics for modulation of foreign body responses that may be elicited by percutaneous and / or subcutaneous devices, including medical devices and other consumer electronic devices. Light delivery structures are disclosed that propagate light from the light sources to irradiate associated subcutaneous tissues. Modulation of foreign body responses may include inhibiting collagen and fibrous tissue generation, modulating inflammation and healing, and / or increasing nitric oxide production and / or release. By modulating foreign body responses associated with percutaneous and / or subcutaneous devices, performance characteristics and lifetimes of such devices may be improved.

Provided is an ophthalmic surgical instrument for cutting an intraocular fibrous tissue, including: a rod body having a long axis; and a cutting portion protruding in a direction away from the length direction of the rod body. The rod body includes: a rod body front surface located in the protruding direction of the cutting portion; and a rod body rear surface located on the opposite side of the protruding direction. The cutting portion includes: a tip end located in the protruding direction of the cutting portion and having a minimum thickness in the length direction of the rod body; a top surface as a connecting surface between the tip end and the rod body front surface; and a bottom surface as a connecting surface between the tip end and the rod body rear surface. When viewed from the side, the center point of a reference cross section that is orthogonal to a horizontal tangent line in a tangent line of a surface or a point that transitions from the top surface to the rod body front surface and that is initially parallel to a horizontal axis extending in the length direction of the rod body and that passes through a tangent point of the horizontal tangent line and the top surface is closer to the rod body rear surface side than a first axis that passes through a center point of a plurality of reference cross sections parallel to the reference cross section that overlaps the most when viewed from the front.

1. The name of the design product: erbium laser treatment instrument (OEM-LSP501). 2. The use of the design product: instrument for treating fibrous tissue repair and beauty. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective drawing.

To provide a tissue structure that facilitates administration of pluripotent stem cells to a disease site, and a method for forming the tissue structure.SOLUTION: A tissue structure formed by a partition wall 12 indwelled in an environment including a biological tissue, wherein the partition wall 12 includes an inner surface 14 surrounding a hollow portion 11 and a plurality of through-holes 13 opened in the inner surface 14, cells in the biological tissue enter the hollow portion 11 through the through-holes to form the tissue structure in the hollow portion 11, and the tissue structure includes a membranous fibrous connective tissue having one side surface peeled from the inner surface 14 and a sparse fibrous tissue spreading over the entire other side surface opposite to the one side surface and having pluripotent stem cells accumulated therein.SELECTED DRAWING: Figure 1

The present invention provides an apparatus, system and method for providing robotically assisted surgery that involves the removal of bone or non-fibrous type tissues during a surgical procedure, in particular with assistance from real-time ultrasound images from an ultrasound probe. The system utilizes a multi-axis robot having a reciprocating tool that is constructed and arranged to remove hard or non-fibrous tissues while leaving soft tissues unharmed. The multi-axis robot may be controlled via computer or telemanipulator, which allows the surgeon to complete a surgery from an area adjacent to the patient to thousands of miles away.

The application belongs to the technical field of covered stents, and relates to a tacrolimus / ZIF-8 airway covered stent and application of the tacrolimus / ZIF-8 airway covered stent in inhibiting airway cicatricial stenosis. Preparation of the tacrolimus / ZIF-8 airway covered stent comprises the following steps: loading tacrolimus on ZIF-8 to obtain tacrolimus@ZIF-8 particles; dissolving PLLA in hexafluoroisopropanol to prepare a PLLA solution; dissolving the tacrolimus@ZIF-8 particles in the PLLA solution to obtain a tacrolimus@ZIF-8 / PLLA solution; and electrospinning the tacrolimus@ZIF-8 / PLLA solution and spraying the solution on a metal bare stent to obtain the tacrolimus / ZIF-8 airway covered stent. The obtained tacrolimus / ZIF-8 airway covered stent has good biocompatibility, a low degree of foreign body reaction, a broad-spectrum antibacterial effect and a multi-pathway inhibition of fibrous tissue proliferation, and can be used for benign airway cicatricial stenosis and prevention of airway restenosis.

An implantable medical device for treating reflux disease includes a movement restriction device configured to be anchored to the stomach wall to prevent movement of the lower esophageal sphincter relative to the thoracic diaphragm. The movement restriction device includes a first portion, a second portion, and a first distance element. The first and second portions are configured to be connected to each other to form at least a portion of a functional movement restriction device. The first and second portions are detachable from each other to allow the first and second portions to pass independently through the gastrointestinal tract, and the first distance element is configured to form a space between the first and second portions, the space being configured to allow fibrous tissue ingrowth between the first and second portions.

This application discloses a tissue cutting device provided by this utility model, including a housing with a through hole for tissue passage, and a cutting mesh for cutting tissue installed in the through hole. This utility model, through customized material selection and a selectable 0.5–5 mm aperture, precisely adapts to different tissues, significantly reducing mechanical stress damage to fragile cells while avoiding the uneven size problems of traditional manual cutting. The use of different material combinations can specifically address the cutting resistance of high-fiber tissues, the adhesion residue of lipid tissues, and the clogging risk of sticky tissues, improving enzymatic hydrolysis efficiency and cell survival rate.

This technical solution relates to a surgical fixation clamp, particularly suitable for microsurgical and ophthalmic surgeries, for example, to prevent longitudinal displacement of fibers, tissues, and other materials. The surgical fixation clamp includes an actuating member (1) and at least one retaining member (7, 2, 3) located in the plane of the actuating member (1) and attached to the actuating member (1); wherein the actuating member (1) is elastically deformable in the plane of the actuating member to drive the jaws (7a, 1a, 2a, 3a) of the clamp to clamp; and wherein (a) a single retaining member (7) is attached to the actuating member (1) and is located outside the actuating member (1); or (b) two adjacent retaining members (2, 3) are attached to the actuating member (1) and are located inside the actuating member (1). Under the action of an adapter, the elastically deformable actuating member (1), which is generally in the shape of a closed planar curve, deforms, thereby controlling the clamping of the jaws.

The application relates to a biological 3D printed tissue engineering trachea and a construction method and application thereof, namely a cartilage / vascularized fiber tissue alternating tissue engineering trachea. The construction method comprises the following steps: firstly, cartilage specific biological ink is prepared by wrapping cartilage cells with cartilage tissue specific hydrogel; fiber specific biological ink is prepared by wrapping fibroblasts with fiber tissue specific hydrogel; then, through a double-needle extrusion type biological 3D printing technology, alternating printing is realized to form a ring-shaped tubular structure, and a cartilage / fiber tissue alternating tubular structure is constructed through multi-layer accumulation molding; further, vascularization of the fiber tissue is realized through a certain culture mode, and finally, a relatively mature cartilage / vascularized fiber tissue alternating tissue engineering trachea is obtained. The application also provides application of the cartilage / vascularized fiber tissue alternating tissue engineering trachea in tracheal defect repair.

Instruments for placing complex sutures into biological tissues, including instruments useful in arthroscopic surgical techniques which minimize incision size. The instruments manipulate tissue by, for example, rolling, wrinkling, folding, bending, or tucking the tissue so that a needle can be placed through the tissue more than once. Sutures are placed, for example from top-to-bottom and bottom-to-top with a single pass of a straight needle. In addition, the instruments can roll, wrinkle, fold, bend, or tuck the flat tissue so that a needle can be placed through the tissue more than once and a loop can be sutured through the tissue so that another suture can pass through resulting in sewing both sides of the tissue. This will allow surgeons to place complex locking and grasping suture configurations that will significantly improve the repair.

Instruments for placing complex sutures into animal tissues, including instruments useful in arthroscopic surgical techniques which minimize incision size. The instruments manipulate tissue by, for example, rolling, wrinkling, folding, bending, or tucking the tissue so that a needle can be placed through the tissue more than once. Sutures are placed, for example from top-to-bottom and bottom-to-top with a single pass of a straight needle. In addition, the instruments can roll, wrinkle, fold, bend, or tuck the flat tissue so that a needle can be placed through the tissue more than once and a loop can be sutured through the tissue so that another suture can pass through resulting in sewing both sides of the tissue. This will allow surgeons to place complex locking and grasping suture configurations that will significantly improve the repair.

A method for treating a patient's skin is provided. The method includes identifying at least one region of said patient's skin in need of treatment. The method includes forming at least one interference of at least one tissue portion in said region of skin, thereby generating at least one scar-like fibrous tissue in said region of said patient's skin. Rotational Fractional Resection (“RFR”) is a procedure which may be used to achieve focal aesthetic contouring by removing fractions of lax skin and excess fat tissue from a patient. Skin may be removed by the use of a rotating micro-coring punch, which is a hollow, sharpened tube which excises full thickness dermal resections. Such punch has been adapted to treat, among other conditions, scars, acne scars, lines, wrinkles, stretch marks, melasma, and to improve skin texture and tighten the skin.

Provided is a tissue construct that is formed using a partition wall 12 placed in an environment comprising biological tissue. The partition wall 12 comprises: an inner surface 14 surrounding a hollow portion 11; and a plurality of through holes 13 opening to the inner surface 14. Cells in the biological tissue infiltrate the hollow portion 11 through the through holes, thereby forming the tissue construct in the hollow portion 11. The tissue construct comprises: a membrane-like fibrous connective tissue that has one surface detached from the inner surface 14; and a loose fibrous tissue that spreads over the entire surface opposite the one surface and has pluripotent stem cells accumulated therein.

Provided is a monopolar skin treatment apparatus using electrical energy in a high frequency wavelength band in which a retaining ligament, a blood vessel, and a fibrous tissue of a deep part is utilized as an electricity passage to actively prevent the skin from sagging due to the aging.

The application relates to a biological 3D printing cartilage-fiber-epithelium integrated tissue engineering trachea and a construction method and application thereof. First, cartilage specific biological ink is prepared by wrapping cartilage cells with cartilage tissue specific hydrogel; fiber specific biological ink is prepared by wrapping fibroblasts with fiber tissue specific hydrogel; epithelium specific biological ink is prepared by wrapping epithelial cells with matrix hydrogel; then, through a step-by-step assembly strategy, a C-shaped cartilage ring and a fiber ring are alternately printed and a ring-shaped tubular structure is formed by using a double-needle extrusion type biological 3D printing technology, and then a layer of epithelium specific biological ink is attached in the lumen to construct a tubular structure of cartilage-fiber-epithelium multi-tissue composite; it is verified that after being implanted subcutaneously in a naked mouse for 8 weeks, a relatively mature cartilage-vascularized fiber-epithelium tissue composite tissue engineering trachea can be regenerated, and a clinically transformable strategy is provided for the regeneration treatment of complex tracheal injury.