24 results about "Valve leaflet" patented technology

The application discloses a heart valve device and relates to the technical field of artificial heart valves, which comprises an outer valve frame and a valve leaflet assembly connected to the inside of the outer valve frame, and the outer valve frame is a ring-shaped grid frame; the outer valve frame comprises an inflow side grid frame and an outflow side grid frame arranged in sequence from an inflow end to an outflow end, and the inflow side grid frame and the outflow side grid frame form an annular recess for clamping a native valve ring on the outer periphery of the outer valve frame; the outflow side grid frame comprises a plurality of groups of grid support units connected in sequence along the circumferential direction and enclosed into a ring, and the grid support unit comprises an outer convex grid support and an inner concave grid support, and the outer surface of the inner concave grid support is arranged in a concave manner relative to the outer surface of the outer convex grid support. In this way, the anterior leaflet of the original mitral valve can be attached to the inner concave grid support, the extrusion of the outer valve frame on the anterior leaflet is reduced, the anterior leaflet is prevented from being extruded to the left ventricular outflow tract by the outer valve frame, and the outflow area of the left ventricular outflow tract is prevented from being reduced to cause obstruction.

This is a low-profile prosthetic half-valve for treating regurgitant heart valves. In one example, the prosthetic valve includes a large upper portion for fixation to the dilated annulus and a small open lower portion that, when implanted, is suspended in the blood flow path near the junction line of the patient's own valve leaflets. The prosthetic valve includes at least one flexible prosthetic leaflet that moves between open and closed positions together with the patient's own valve leaflets. During operation, at least one prosthetic leaflet acts as a symmetrical junction surface for at least one of the patient's own valve leaflets, and the posterior side of the lower portion of the frame acts as a junction surface for at least one of the patient's own valve leaflets to completely seal the valve orifice of the patient's own valve. Optionally, the frame may include an open flow path to facilitate diastolic filling of the ventricle.

The application provides a valve leaflet extension device, which comprises a delivery catheter, a first clamping arm, a second clamping arm, an opening and closing rod and a locking assembly, the first clamping arm is fixedly arranged at the distal end of the delivery catheter, the second clamping arm is rotationally connected to the proximal end of the first clamping arm, the opening and closing rod is connected to the proximal end of the second clamping arm and is used for opening or closing the second clamping arm, and the locking assembly comprises a blocking piece and a push rod connected with the blocking piece, and the push rod is used for driving the blocking piece to move to block the opening of the second clamping arm. The valve leaflet extension device of the application is provided with the opening and closing rod and the locking assembly, the push rod drives the blocking piece to move to block the opening of the second clamping arm, and the technical problem that the second clamping arm is pried up and tilted during the puncture process and causes the failure of the operation is solved.

Endovascular valve formation systems with imaging capabilities and associated devices and methods are disclosed herein. In some embodiments, a valve formation and imaging system can include, for example, (i) a valve formation device configured to access a vessel wall and dissect a portion of the vessel wall to form an autologous valve leaflet and (ii) an imaging device configured to image the vessel wall and components of the valve formation device during a valve formation procedure. In some embodiments, the imaging device is integrated into a distal end portion of the valve formation device. In some embodiments, the imaging device is a separate catheter device positionally coupled to the valve formation device and / or components thereof.

A method of making a valvular medical device including a cell configured to flex out-of-plane upon application of a lateral or circumferential force applied to the biased cell, the biased cell having an elongate member projecting axially from an apex of the biased cell that flexes out-of-plane concomitantly with out-of-plane flexion of the biased cell. A monolithic hypotube is formed into a lattice structure having a plurality of biased cells and elongate members and is configured into a cardiac valve having a main body portion, a valve leaflet portion, and a plurality of elongate biasing arm members. A polymer coating or covering is disposed on the valve leaflet portion and the elongate biasing arm members and subtends space between adjacent pairs of elongate biasing arm members to form valve leaflet cusps that are biased toward a central axis of the cardiac valve by the elongate biasing arm members.

Methods and assemblies are disclosed for attaching leaflets to a frame of a prosthetic heart valve using a connecting skirt. As an example, the prosthetic heart valve may include an annular frame with a plurality of struts and a valve leaflet structure mounted within the frame and comprising a plurality of leaflets. A leaflet portion of each leaflet may be connected to the frame by a connecting skirt, where each connecting skirt includes a central portion and opposing side base portions on opposing sides of the central portion connected to and disposed between each of the frame and the leaflet leaflet portion, and each connecting skirt may further include a side extension portion extending outwardly from the leaflet leaflet portion and across the struts of the frame disposed between the leaflet leaflet portions of two adjacent leaflets.

The application relates to the technical field of medical devices, and provides an artificial heart valve leaflet and a heart valve prosthesis, which comprise a valve leaflet body and a first edge reinforcing part; the valve leaflet body comprises a free edge part; a laminated structure is formed between the first edge reinforcing part and the free edge part; the first edge reinforcing part is formed by extending the free edge part, or the first edge reinforcing part is connected to the free edge part. In the application, the first edge reinforcing part is arranged, and the laminated structure is arranged between the first edge reinforcing part and the valve leaflet body, so that the stress performance of the edge of the valve leaflet body used for participating in the valve closing action can be improved, the application reliability of the artificial heart valve leaflet can be improved, and the service life of the artificial heart valve leaflet can be prolonged.

This invention relates to an artificial heart valve material, its preparation method, and an artificial heart valve device, belonging to the field of medical polymer materials and medical device technology. The main technical solution adopted is as follows: the artificial heart valve material is a composite structure film; the composite structure film includes a support layer located in the middle and encapsulation layers located on both sides of the support layer; the support layer is a porous polytetrafluoroethylene (PTFE) membrane; the encapsulation layers are polyurethane (PU) membranes; the polyurethane in the encapsulation layers permeates into the micropores of the porous PTFE membrane, forming a physically interpenetrating structure. This invention mainly solves the problem of insufficient bonding strength between polyurethane and PTFE in traditional composite methods. The valve material of this invention, used in the preparation of artificial heart valve devices, possesses good fatigue and tear resistance. When microcracks develop in the valve leaflets under long-term fatigue operation, this material can prevent the microcracks from expanding, effectively improving the fatigue life of the artificial heart valve device.

Clasps for valve repair devices, valve repair devices and systems are configured to detect proper valve leaflet insertion. The device can have a paddle and a movable clasp arm. The movable clasp arm can have first and second spaced apart sides. The paddle and the movable clasp arm are moveable to form an opening between the movable clasp arm and the paddle. The device can include an indicator arm disposed between the first and second spaced apart sides of the movable clasp arm. The indicator arm is moveable in the opening to indicate whether a leaflet of the native valve is inserted into the opening between the paddle and the movable clasp arm to at least a minimum desired insertion depth.

The application relates to a valve repair device and a clamping assembly, the clamping assembly comprising a moving piece and a fixed piece, the moving piece having a long axis extending along a length direction and a short axis extending along a width direction, the long axis intersecting the short axis, the moving piece being further provided with a matching surface for matching with a valve leaflet, the matching surface being used for abutting against the valve leaflet when clamping the valve leaflet. Further, a plane passing through the long axis and the short axis of the moving piece is defined as a first reference plane, and the matching surface is arranged to form an angle with the first reference plane passing through the long axis and the short axis. Further, the fixed piece is connected with the moving piece, and the fixed piece is used for cooperating with the moving piece to clamp the valve leaflet. The valve repair device and the clamping assembly can be further compressed in volume during transportation, the size of the clamping assembly is reduced, the size of the valve repair device and related components of a conveying system is effectively reduced, the valve repair device is convenient to transport, and the operation safety is improved.

The application discloses a valve prosthesis, comprising an inflow end, an outflow end and a main body part, two ends of the main body part are connected with the inflow end and the outflow end respectively, the maximum circumference of the main body part is greater than the maximum circumference of the inflow end or the outflow end; further comprising a valve leaflet assembly, the valve leaflet assembly is connected with the inner wall of the main body part, the maximum circumference of the valve leaflet assembly is greater than the maximum circumference of the inflow end or the outflow end. Thus, by the maximum circumference of the main body part being greater than the maximum circumference of the inflow end or the outflow end, the valve leaflet assembly is connected with the inner wall of the main body part, the maximum circumference of the valve leaflet assembly is greater than the maximum circumference of the outflow end or the outflow end, so that the opening area of the valve leaflet assembly is increased, so as to facilitate the blood flow through the valve leaflet assembly and promote the blood circulation.

The application provides a valve stent and a valve prosthesis, the valve stent comprising an outer layer stent, an inner layer stent and at least one buffer part; the outer layer stent is sleeved outside the inner layer stent and is connected with the inner layer stent through the buffer part. The buffer part can effectively reduce the influence of the deformation of the outer layer stent on the opening and closing of the valve leaflet on the inner layer stent, so that the buffer part can significantly weaken or isolate the mutual force between the outer layer stent and the inner layer stent. In addition, the valve stent adopts the design of double-layer stent, which can effectively improve the fatigue resistance of the valve prosthesis, make the valve prosthesis more fit the original tissue, reduce the influence of the valve stent on the ventricular contraction capacity and ensure the stability of the closed valve stent.

A venous valve prosthesis for transporting a flow of body fluid in a vessel in a predetermined direction includesincludes a hollow-cylindrical support structure. A skirt is connected to the support structure and forms a closed, circumferential jacket of the support structure. The prosthesis also includes a valve leaflet arrangement with a first valve leaflet and a second valve leaflet, each being connected to the skirt. A downstream edge of the first valve leaflet and a downstream edge of the second valve leaflet are opposite to each other and configured in such a manner that in a first state of the valve leaflet arrangement they form an opening for blood to flow through in the predetermined direction and in a second state of the valve leaflet arrangement the opening is closed and to prevent a backflow of blood in a direction opposite to the predetermined direction. A ratio of the inner diameter of the support structure to its length in the predetermined direction is at most 1.

The application discloses a kind of TAVI postoperative automatic analysis and visualization system based on medical image, including data import, automatic analysis, valve leaflet function evaluation, valve stent geometry evaluation, interactive alignment and report generation module.System imports time series medical image data covering at least one cardiac cycle, segments aorta, coronary artery, left ventricle, valve stent and calcified structure, extracts stent central axis and establishes stent local coordinate system, generates transverse, longitudinal, bottom, coronary artery opening and walsh sinus reconstruction plane.Based on multi-plane reconstruction display, the system evaluates HALT, SFD and PFD, and calculates perimeter, area, long-short diameter, AED and PED and other parameters at stent inflow end, valve leaflet nadir and commissure height plane.Interactive alignment module maps valve structure to standard observation plane and superimposes simulated valve model, and report generation module integrates results to output structured report.

The application provides a valve leaflet for a heart valve and a preparation method thereof, and relates to the technical field of heart valves.The valve leaflet for the heart valve can include a valve leaflet body and a reinforcing member.The valve leaflet body includes a reinforcing region selected from one or more of a commissure region, a coaptation region and a free edge region.The reinforcing member corresponds to the area and structure of the reinforcing region and is combined on one side or both sides of the reinforcing region.The valve leaflet of the embodiment improves the durability of the valve leaflet by arranging the reinforcing member on the reinforcing region of the valve leaflet body, thereby avoiding the early tearing of the valve leaflet during work.In addition, the stress distribution of the entire valve leaflet is more uniform through the reinforcement of the reinforcing member, while the performance of the valve leaflet body material is not affected, thereby meeting the synchronous improvement requirements of the fluid mechanics performance and the durability performance of the valve leaflet material.

Cardiac conditions such as valve regurgitation can be treated using implantable clip devices. Some clip devices include two or more separate clips, which are individually attached to the natural valve leaflets and then connected to each other. The completed placement can serve to maintain the valve leaflets held in close or near-close contact with each other by the clips.

The present invention relates to a valve leaflet cutting apparatus and system. The valve leaflet cutting apparatus comprises at least a distal-end cutting portion. The distal-end cutting portion comprises a main body member, a cutter head, a clamping arm, and a moving member. The cutter head is arranged inside the main body member and is capable of axially moving between the distal end and the proximal end of the main body member, and the cutter head is provided with double-sided cutter edges for cutting a valve leaflet; the proximal end of the clamping arm is rotatably connected to the main body member, and the distal end is configured to clamp and fix the valve leaflet; the moving member is slidably connected to the clamping arm, and the moving member can move axially relative to the main body member, so as to drive the clamping arm to rotate around the main body member, thereby achieving the opening and closing of the clamping arm. When the clamping arm is closed and fixes the valve leaflet, the axial movement of the cutter head implements cutting of the fixed valve leaflet.

To provide improved devices and methods for treating mitral valve regurgitation. [Solution] The implantable artificial spacer device comprises an inflatable spacer having a plurality of inflatable members, and a frame, the frame may include one or more anchors and one or more clasps. The inflatable spacer may be configured to be positioned between the natural valve leaflets of the heart. The implantable artificial spacer may be positioned in a symmetrical or asymmetrical configuration. The inflatable spacer may be inflatable between a non-inflatable configuration and an inflatable configuration.

This invention provides a polymer valve leaflet composite material for artificial hearts and its preparation method. The method involves first impregnating a fabric substrate with a first polymer to fill at least a portion of the interior with a first polymer. Then, a second polymer film is repeatedly coated onto one side of the fabric substrate. The fabric substrate is then flipped over and placed on a platform, and a third polymer film is repeatedly coated onto the other side of the substrate. This process ultimately yields a polymer valve leaflet composite material for artificial hearts with no obvious internal interface and excellent performance. In the above process, the impregnation method for preparing the first polymer film allows the solution to penetrate into the fabric, completely filling the gaps between the fibers and effectively avoiding defects such as voids within the material. During the subsequent coating process, by controlling the process parameters, the compatibility within the polymer layer is effectively enhanced, preventing the formation of an interface between the coating layer and the first polymer film, thus enhancing the overall stability of the material and preventing delamination between the substrate and the polymer coating during long-term use.

The application provides an artificial heart valve, which comprises a support and an artificial valve leaflet, the artificial valve leaflet is connected with the support, the support is divided into an inflow tract and an outflow tract in the axial direction, the outflow tract has a plurality of support sewing rods which are concave in the direction of the inflow tract and are arranged in an arc shape, and a blank area is formed on the side of the support sewing rods away from the inflow tract, the plurality of support sewing rods are sequentially arranged in the circumferential direction of the support, the two ends of the adjacent two support sewing rods are connected through a support window, the artificial valve leaflet comprises a valve leaflet free edge part, a valve leaflet commissure part and a valve leaflet fixed edge part, the two ends of the valve leaflet free edge part and the valve leaflet fixed edge part are connected through the valve leaflet commissure part, the valve leaflet fixed edge part is sewn and fixed with the support sewing rod, and the valve leaflet commissure part is sewn and fixed with the support window. The application can make the blood flow fully flow during the opening and closing of the artificial valve leaflet, avoid the formation of a dead zone of blood flow stagnation, and reduce thrombosis.

The application relates to the field of medical devices, in particular to an aortic valve annuloplasty system, which comprises a delivery device and an annuloplasty device, the annuloplasty device comprising an annuloplasty ring, three clamping and locking devices, an annuloplasty cord and a locking device, the annuloplasty cord being connected with the clamping and locking devices; the delivery device comprising a control catheter and an adjusting control, the control catheter being used for being connected with the clamping and locking devices, and the adjusting control being used for being connected with the locking device; the control catheter is operated to make the clamping and locking devices capture and anchor the valve leaflet tissue at the junction of the valve leaflets, and the locking device is used for being arranged at the central area of the aortic valve and sleeved on the periphery of the annuloplasty cord; in the application, the clamping and locking devices capture and anchor the valve leaflet tissue at the junction, so that the junction of the valve leaflets is closed, and in combination with the pulling action of the annuloplasty cord, the circumference of the valve annulus is effectively reduced, the double repair effect on the valve is realized, and the regurgitation problem of the aortic valve is effectively improved.

Clasps for valve repair devices, valve repair devices and systems are configured to detect proper valve leaflet insertion. The clasp and / or device can have a fixed arm, a moveable arm and a hinge portion hingeably connecting the moveable arm to the fixed arm. The clasp and / or device can include a first marker disposed on the movable arm and an indicator comprising a second marker. The clasp and / or device can be configured such that the first marker is adjacent to the second marker when the movable arm is in the closed position and a leaflet of a native valve is not inserted to a minimum insertion depth in the clasp and the first marker and the second marker are spaced apart when the movable arm is in the closed position and the leaflet of the native valve is inserted to the minimum insertion depth in the clasp.

The application discloses a heart valve replacement device, which comprises a support base and a replacement valve, wherein the support base comprises a support framework, the support framework has a hollow structure, and along the central axis direction of the hollow structure, the two ends of the support framework are respectively provided with a myocardial fixing end and a valve leaflet and chordae tendineae fixing end; the myocardial fixing end is used for fixing the support base to the myocardium and / or the native valve annulus of the heart; and the valve leaflet and chordae tendineae fixing end is used for fixing the support base to the valve leaflet and chordae tendineae of the heart; the replacement valve comprises a hollow valve framework and a valve arranged on the valve framework, and the valve framework is detachably arranged in the hollow structure. The application can solve the problem of difficult valve fixation, does not affect the diastole and systole of the myocardium at the valve annulus part, and reduces the heart work efficiency reduction caused by the implanted valve. The application also provides a method for conveying and releasing the heart valve replacement device.