213 results about "Valve leaflet" patented technology

A prosthetic heart valve and associated methods for assembling a prosthetic heart valve including a plurality of leaflets is disclosed. As one example, a prosthetic heart valve includes a frame; a plurality of commissure support elements, each connected the frame and including two axially-extending members spaced apart from one another to form a window; and a plurality of leaflets, each leaflet comprising a body and two opposing commissure tabs, each commissure tab arranged adjacent to another commissure tab to form a pair of commissure tabs that are disposed in a commissure support element to form a commissure. Each commissure tab includes a series of overlapping layers that include a first set of two overlapping layers that extends through the window and a second set of two overlapping layers that extends away from the first set of two overlapping layers and over an outer side of a corresponding axially-extending member.

The invention relates to the technical field of cardiovascular examination, in particular to a cardiovascular ultrasonic examination quality control method and system based on artificial intelligence, and the method comprises the following steps: obtaining a valve motion image through ultrasound, extracting a valve leaflet edge coordinate, recognizing a valve opening center and a valve leaflet tip through a convolutional neural network, and generating motion data; the method comprises the following steps: calculating a deviation degree based on trajectory fitting, judging stability, analyzing peak values of a systolic period and a diastolic period, calculating a symmetry difference, extracting a valve opening area, carrying out self-encoder analysis in combination with the symmetry difference to generate a fluctuation amplitude, and carrying out normalization processing to complete hierarchical classification so as to generate a quality control result. By acquiring leaflet edge points and combining a convolutional neural network to identify key features, accurate extraction of motion data, finer trajectory fitting and offset calculation, more scientific quantitative evaluation of symmetry difference and more stereoscopic area fluctuation and feature fusion analysis are realized, hierarchical and hierarchical synchronization is realized through normalization processing, and the accuracy of the motion data is improved. And the result is more credible, more stable and higher in clinical value.

Prosthetic heart valves and methods for assembling prosthetic heart valves are disclosed. As one example, a prosthetic heart valve includes a frame, commissure support elements, and leaflets, each leaflet comprising a body and opposing commissure tabs, each commissure tab folded over from a corresponding body to form a bend between the commissure tab and body and arranged adjacent to another folded commissure tab of an adjacent leaflet to form a pair of commissure tabs that is coupled to one commissure support element to form a commissure. Each commissure tab is secured to the commissure support element via a reinforcement member positioned against the commissure tab, adjacent to the bend, and secured to and / or at least partially wrapped around the commissure tab and the commissure support element, the reinforcement member comprising a flexible body and a more rigid, central portion, the central portion positioned along a height of the commissure tab.

The invention discloses a TAVR postoperative blood flow parameter complementing method based on CT-MRI fusion, and belongs to the technical field of crossing of medical image processing and computational fluid mechanics. A CT valve frame registration technology is adopted, an invisible artificial valve leaflet three-dimensional structure is reconstructed through valve frame information in a CT image and is coupled with a dynamic heart model, a complete valve mechanical and functional simulation platform is constructed, the problem of an imaging blind area is solved, hemodynamic parameters of an inlet and an outlet of a postoperative area are further collected in combination with 4D Flow MRI, and the artificial valve leaflet three-dimensional structure is obtained. The blood flow conditions of the upstream and the downstream of the artificial valve area at each stage of contraction and relaxation of the TAVR postoperative part are comprehensively restored, the temporal-spatial resolution and the physical authenticity of the boundary condition in fluid-solid coupling simulation are greatly improved, and the more real passive response of the valve leaflet under the action of the blood flow is obtained; and a reliable basis is provided for quantitative and mechanical risk analysis of postoperative complications such as thrombosis, perivalvular leakage and valve leaflet fatigue.

Provided is a prosthetic valve replacement system. A hoop member is at least partially disposed on a valve clamping mechanism. A valve clamping and securing mechanism is configured to present a first form and a second form, and the second form is present after the first form. When the valve clamping and securing apparatus is in the first form, the valve clamping mechanism is configured to capture and clamp autologous valve leaflets. After the radial expansion of a valve stent, the valve clamping and securing apparatus is in the second form.

A device and method of inhibiting and preventing damage to leaflets during the crimping of a prosthetic valve, and / or facilitating the folding of the leaflets during the crimping of a prosthetic valve.

A replacement heart valve implant includes an expandable framework including a tubular wall comprising a plurality of interconnected struts and defining a central lumen, wherein the wall includes inflow and outflow ends, and a plurality of commissure posts. A plurality of valve leaflets is secured to the commissure posts. The framework may include a plurality of native leaflet clamps extending upstream from the outflow end, wherein the leaflet clamps are configured to pinch native leaflets of the native heart valve against the wall. The framework may include a plurality of native commissure clamps extending upstream from the commissure posts, wherein the commissure clamps are configured to pinch native commissures of the native heart valve. The framework may include a plurality of native leaflet clamps extending upstream from the commissure posts, wherein the leaflet clamps are configured to pinch native leaflets of the native heart valve against the wall.

The invention relates to a high-molecular artificial heart valve and a preparation method thereof. The high-molecular artificial heart valve is composed of a specially-designed valve support and high-molecular valve leaflets. The inflow end of the valve support extends outwards in the radial direction relative to the outflow end to form a circumference, through holes are distributed in the circumference, a plurality of arc-shaped sections are formed at the outflow end and used for attachment of valve leaflets, reinforcing ribs are arranged on the outer walls of the arc-shaped sections, arc-shaped grooves are formed in the surfaces of the arc-shaped sections, and convex stand columns are arranged at the junctions of the adjacent valve leaflets at the top of the outflow end between the adjacent arc-shaped sections. The preparation method adopts a step-by-step dip-coating curing process and comprises the steps of pre-dip-coating, formal dip-coating and annealing heat treatment. By optimizing the structural design and preparation process of the valve stent, the combination firmness of the valve stent and the high-molecular valve leaflet is remarkably improved, the pore defect between the valve stent and the high-molecular valve leaflet is effectively reduced, and the internal stress of the valve leaflet under the blood flow load is reduced, so that the service life of the high-molecular valve is greatly prolonged; and the reliability and the durability in practical application are improved.

The valve leaflet screening and matching device comprises a detection box, the detection box is provided with a plurality of movable pulley sets, the movable pulley sets are connected through pull ropes, one end of each pull rope is fixedly connected to the top of a supporting frame, and the other end of each pull rope is connected with a balancing weight; the detection box is provided with a connecting assembly on the movable pulley, and the detection box is provided with a positioning assembly under the movable pulley; an electronic displacement sensing device is arranged at the position, corresponding to the balancing weight, of the detection box, the electronic displacement sensing device can detect the displacement amount of the balancing weight and send detected data to a computer, and the computer uses a screening and matching program to conduct matching of a set of three valve leaflets according to preset screening and matching parameters. The extension length of the valve leaflet when the heavy object is pulled down can be amplified through the pulley block, then the extension length of the valve leaflet is accurately measured, the screening precision is improved, meanwhile, the labor cost is reduced, the subjectivity of manual matching is reduced, and the screening and matching of the valve leaflet are more objective and parameterized.

The utility model relates to the technical field of interventional medical instrument in-vitro simulation demonstration, in particular to a structural heart disease interventional medical instrument in-vitro simulation demonstration device. The device comprises a model fixing device (3), a heart model (31) and a detachable valve leaflet model (32) are fixed on the model fixing device (3), a camera (5) is further arranged on the device, and the device can be used for simulation device demonstration of heart valve intervention medical instrument in-vitro performance research, instrument operation training of an operator in vitro and operation process practice.

The application discloses a heart valve device and relates to the technical field of artificial heart valves, which comprises an outer valve frame and a valve leaflet assembly connected to the inside of the outer valve frame, and the outer valve frame is a ring-shaped grid frame; the outer valve frame comprises an inflow side grid frame and an outflow side grid frame arranged in sequence from an inflow end to an outflow end, and the inflow side grid frame and the outflow side grid frame form an annular recess for clamping a native valve ring on the outer periphery of the outer valve frame; the outflow side grid frame comprises a plurality of groups of grid support units connected in sequence along the circumferential direction and enclosed into a ring, and the grid support unit comprises an outer convex grid support and an inner concave grid support, and the outer surface of the inner concave grid support is arranged in a concave manner relative to the outer surface of the outer convex grid support. In this way, the anterior leaflet of the original mitral valve can be attached to the inner concave grid support, the extrusion of the outer valve frame on the anterior leaflet is reduced, the anterior leaflet is prevented from being extruded to the left ventricular outflow tract by the outer valve frame, and the outflow area of the left ventricular outflow tract is prevented from being reduced to cause obstruction.

Embodiments include a valve leaflet for an implantable valve device comprising a leaflet body. The leaflet body comprising a free edge configured for coaptation with free edges of one or more other valve leaflets; and a root edge disposed opposite the free edge. The free edge defining an edge profile comprising a peak and valleys disposed on opposite sides of the peak. Other embodiments are also included herein.

Disclosed in the present application are an artificial heart valve, an interventional system, and a position registration method for an artificial heart valve. The artificial heart valve comprises: a stent, which is of a cylindrical structure and has a spatially axial direction, the interior of the cylindrical structure being a blood flow channel, and the stent being radially deformable so as to switch between a delivery state in which the stent is radially compressed and a deployed state in which the stent is radially deployed; valve leaflets, which are connected to the stent to control the blood flow channel; and a first radiopaque marker, which is connected to the stent. At the reference angle of viewing of the stent, when the stent rotates around its own axis, the distance between the projection position of the first radiopaque marker and the axis of the stent changes correspondingly.

The invention relates to a valve prosthesis which comprises a stent body and a valve leaflet, the stent body comprises an outflow end and an inflow end, the stent body comprises an inner stent and an outer stent, the inner stent is arranged in the outer stent, the valve leaflet is arranged in the inner stent, and the outflow end comprises a plurality of connecting points. The outer-layer stent and the inner-layer stent are connected with the connecting points after being connected at the outflow end or at the position close to the outflow end, a circle is defined by the multiple connecting points, the circle is provided with a circumference, the circumference is equally divided by the multiple connecting points, on one hand, it can be guaranteed that the outflow end of the stent body is of a symmetrical structure, and the stent body can be evenly compressed into a conveying sheath tube; on the other hand, it can be guaranteed that the stent body is evenly stressed when placed at the lesion position, and therefore the stent body is not prone to falling off.

The application belongs to the technical field of interventional medical instruments, and particularly relates to a valve frame for a pulmonary valve and a pulmonary valve. The valve frame comprises a tubular middle part, a proximal end part and a distal end part connected to the axial two ends of the middle part respectively, the middle part comprises a plurality of grid structures, the distal end part comprises a plurality of unit bodies with an 'M' shape, and the number of the unit bodies is m, m is a natural number greater than or equal to 2. The pulmonary valve comprises a valve leaflet and the valve frame, and the valve leaflet is connected to the valve frame. The valve frame provided by the application can be uniformly expanded, and the overall shape is consistent. The pulmonary valve can be uniformly expanded by adopting the valve frame, and the use requirement that the pulmonary valve can be uniformly expanded is well met, and the use reliability is good.

The invention discloses an intelligent artificial heart valve integrated with pressure sensing, which comprises an implantation end and a body surface relay patch, the implantation end comprises a stent valve main body, a valve crossing pressure sensor pair, a microelectronic module and a flexible circuit, and the stent valve main body comprises a valve frame and a valve leaflet. The transvalvular pressure sensor pair comprises a first pressure sensor fixed to the ventricular proximal side of the stent valve body and a second pressure sensor fixed to the ventricular distal side of the stent valve body, leads of the pressure sensors are electrically connected with the microelectronic module through a flexible circuit, and the flexible circuit comprises a planar spiral coil; the plane spiral coil is electrically connected with the microelectronic module, the body surface relay patch comprises an external read-write coil, the external read-write coil transmits energy to the plane spiral coil, and the cross-lobe pressure sensor sends sensed data to the external read-write coil through the plane spiral coil. According to the invention, abnormal early warning can be realized, the treatment lagging is shortened, and the complication cost is reduced.

The disclosure provides a subclinical valve leaflet thrombosis auxiliary identification method, system and signal acquisition device after transcatheter aortic valve replacement, belonging to the technical field of heart information acquisition and identification. The subclinical valve leaflet thrombosis auxiliary identification method is used for auxiliary diagnosis of subclinical valve leaflet thrombosis after transcatheter aortic valve replacement, comprising: collecting a heart sound signal, processing the heart sound signal, obtaining preset parameters of the heart sound signal, and the preset parameters at least including time, frequency and energy; determining a systolic period according to the heart sound signal; identifying the highest energy point in the characteristic interval of the systolic period; obtaining the characteristic frequency corresponding to the highest energy point, and judging whether the characteristic frequency is greater than the threshold frequency, if yes, marking the heart sound signal as an abnormal heart sound signal caused by subclinical valve leaflet thrombosis; if not, marking the heart sound signal as a normal heart sound signal. The method solves the problem that the subclinical valve leaflet thrombosis detection mainly uses multi-dimensional computed tomography, which leads to limited scope of application.

The application relates to the field of medical devices, in particular to an implant capable of avoiding interlayer reflux, which comprises an anchoring device, a closing aid, and an adjusting mechanism, the closing aid is fixed on atrial tissue through the anchoring device, one end of the adjusting mechanism is connected with the closing aid, and the other end of the adjusting mechanism is fixed on ventricular tissue or apical tissue, the closing aid comprises a first patch and a second patch, one side of the first patch close to the anchoring device is a root, and the other side of the first patch away from the anchoring device is a head, wherein the first patch is arranged above the second patch, and the first patch and the second patch cooperate to form a pocket structure with an opening direction towards the head direction; the application can effectively avoid the existence of a gap between the closing aid and the autologous valve leaflet, so that blood flowing into the gap can be prevented from being accumulated into thrombus, calcified and other adverse conditions, and the application has good clinical significance.

The application provides a rotating type artificial mechanical heart valve, and belongs to the technical field of heart valves, and comprises: a valve ring; a valve leaflet group, which is rotationally arranged in the valve ring; when the valve leaflet group is in an open state, a spiral channel is formed in the valve ring; and when the valve leaflet group is in a closed state, the valve leaflet group limits blood flow through the valve ring; the rotating type artificial mechanical heart valve of the application forms a spiral channel with the same rotation direction as the blood rotation flow state when the valve leaflet group is in the open state; the spiral channel is arranged to effectively rotate the blood flow, generate corresponding spiral flow state, and the rotation of the outlet blood flow is beneficial to the full flow and development of the blood flow in the aorta, reduces the turbulence, stagnation area and damage to the normal rotation flow state in the aorta, and the heart valve provided by the application has excellent hemodynamic characteristics and can effectively inhibit the aortic dilation complication caused by aortic valve replacement.

The invention relates to the technical field of medical instruments, in particular to a forward torque self-locking mitral valve replacement valve stent which comprises an annular atrial umbrella disc and a plurality of flexible supporting parts which are sequentially connected in the circumferential direction to form the atrial umbrella disc. Due to the arrangement of the inner concave sections, the grid units form outer edge parts which are bent in the circumferential direction, and the bending direction of the outer edge parts is the instantaneous needle direction; the annular support anchoring disc is formed by sequentially connecting a plurality of anchoring arms in the circumferential direction, the circumferential bending direction of the anchoring arms is the same as the circumferential bending direction of the outer edge part, and the anchoring arms are matched with the grid units. The valve support has the advantages that the forward torque self-locking effect can be generated, the valve support continuously winds and hooks the chordae tendineae, the attaching force of the valve support and an original valve leaflet is kept, the valve is prevented from shifting and slipping, and the perivalvular leakage risk is reduced.

The invention provides an artificial valve leaflet connecting structure and method in the technical field of medical instruments, the artificial valve leaflet connecting structure comprises an artificial valve leaflet, lugs, a connecting piece, a support and a suture line, the lugs and creases are arranged at the two ends of the artificial valve leaflet, and the lugs at the two ends are folded along the creases. The two ends of the artificial valve leaflets are aligned and tightly attached to each other side by side, the lugs comprise the first lug and the second lug, and the first lug and the second lug are arranged along the creases in a folded mode. According to the valve leaflet connecting method, one end of the connecting piece is connected with the second folded convex lug in a bent and embedded mode, the other end of the connecting piece is connected to the support in a bent and buckled mode, the suture line sequentially penetrates through the connecting piece, the convex lug and the end of the artificial valve leaflet, and the connecting piece, the convex lug, the end of the artificial valve leaflet and the support are fixedly connected through the suture line; the connecting structure is used for achieving firm connection between the ends of the adjacent artificial valve leaflets, so that the artificial valve leaflets are stably opened and closed, and the probability that blood flows between the ends of the adjacent artificial valve leaflets to generate a reflux phenomenon is reduced.

The invention discloses an integrated valvular catheter and a preparation method thereof, relates to the technical field of medical instruments, and aims to solve the problems that in a traditional valvular catheter operation, suturing is tedious, tearing and thrombus risks exist, and adaptability is insufficient. The integrated valve-containing pipeline is composed of a valve leaflet and a pipeline body which are integrated through the sintering effect, sewing is not needed, and the reflux and thrombus risks caused by sewing gaps are effectively avoided; a metal memory alloy support is embedded in the wall of the pipeline, so that support can be provided for the valved pipeline to stabilize haemodynamics and prevent the pipeline from collapsing, endovascular intervention delivery can be achieved, and the device is adaptive to a surgical opening mode or an endovascular implantation mode and is used for replacing the valved pipeline at parts such as pulmonary artery and lower limb deep vein of a human body and recovering the function of the damaged valve.

The invention relates to the field of medical instruments, in particular to a prosthesis capable of treating valve regurgitation, which comprises a stent main body capable of expanding in the radial direction, the stent main body comprises a plurality of rhombic grids and at least three clamping pieces arranged at the outflow end of the stent main body, and the clamping pieces are used for positioning aortic sinus and clamping autologous valve leaflets; a sealing bag bulging outwards is arranged on the stent body between the adjacent clamping pieces, the position of the sealing bag corresponds to the junction area of the aortic valve leaflet, the sealing bag is attached to the tissue of the junction area of the aortic valve leaflet, and the structure of the sealing bag is configured in a way that when blood regurgitates, the sealing bag can seal the tissue of the junction area of the aortic valve leaflet. The regurgitated blood is guided to be shunted to the two sides into the adjacent aortic sinus; the sealing bag enables backflow blood to flow into the adjacent aortic sinus in a guiding and shunting mode, backflow of the blood is avoided, meanwhile, when blood is pumped next time on the aorta, the blood in the aortic sinus is ejected out, and thrombus caused by blood deposition is avoided.

The present invention provides an expandable polymeric heart valve. The expandable polymeric heart valve comprises valve leaflets and a valve frame, the valve frame being a hollow columnar structure. The valve further comprises an insert, the insert being adapted to be embedded in the valve frame along an axial direction. At least one expansion slot is circumferentially formed on the insert, the expansion slot having a closed state and an open state. An outer wall of the insert at both ends of the expansion slot is provided with a limiting structure, the limiting structure defining an expansion width when the expansion slot is in the open state. When the expansion slot is in the closed state, a cross-section of the insert presents as a closed ring, the insert has a first diameter, and the heart valve is in an original state for normal use, allowing blood to flow unidirectionally. When the expansion slot is in the open state, the cross-section of the insert presents as a circular ring with an opening, the insert has a second diameter greater than the first diameter, and the heart valve is in an expanded state, allowing for valve-in-valve implantation. The present invention achieves expandability of the valve after damage, while ensuring the blood flow performance of the valve in the original state during normal use.

To provide methods and apparatuses for bisection of heart valve leaflets using a catheter having a cutting element.SOLUTION: The invention is a device, system, and method for repairing the heart valve function, which may include bisecting native valve leaflets for improved deployment of a prosthetic heart valve in the native valve annulus. The invention may include a catheter having a cutting element shaft with a cutting element configured to puncture a valve leaflet and / or make a controlled cut through the leaflet. The device may have an extendable foot configured to be positioned on an opposite side of the valve leaflet from the cutting element shaft. The device may include magnets to guide the cutting element and / or cutting element shaft in proper alignment with the extendable foot and to hold the elements in place during leaflet bisection.SELECTED DRAWING: Figure 7

A medical device that is adapted for excising a valve leaflet portion of a valve leaflet from a heart valve includes an elongate shaft including a distal region and an inflatable balloon that is secured to the distal region and that is adapted to extend through the heart valve. The inflatable balloon has an outer surface and includes a deflated configuration and an inflated configuration. An electrocautery electrode is disposed relative to the inflatable balloon such that the electrocautery electrode is positioned to excise the valve leaflet portion when RF energy is applied to the electrocautery electrode and the inflatable balloon is in the inflated configuration. In some cases, the heart valve includes an artificial heart valve. In some cases, the valve leaflet includes an artificial valve leaflet.

Leaflets for a prosthetic heart valve are disclosed. As one example, a leaflet includes a main body with a free, outflow edge and a cusp edge portion, where the outflow edge is straight or curved towards the cusp edge portion, two lower tabs disposed on opposite sides of the main body, where the cusp edge portion terminates at upper ends thereof at the lower tabs, and the lower tabs extend laterally outward from the main body relative to a central longitudinal axis of the leaflet, and two upper tabs disposed on opposite sides of and extending laterally outward from the main body. The leaflet further includes two offsetting portions, each extending between a respective lower tab and upper tab and offsetting the respective upper tab axially and laterally away from the outflow edge of the main body.

The present invention relates to an implantable artificial device, such as an artificial heart valve, and to a mounting configuration and method for attaching a soft component, such as a valve leaflet or skirt, to the frame of such an artificial valve. [Solution] The valve leaflets are connected to the struts of the frame via primary sutures, which are passed in an in-and-out pattern along the cusp end portion of the valve leaflets, and the secondary sutures are passed around the struts through the primary sutures and have a plurality of self-tightening structures configured to contract on the struts under tension.

Described herein are methods and apparatus for implanting grafts to leaflets for cardiac procedures that are performed minimally-invasively while the heart is beating. The graft elongates, reinforces, and patches the leaflet. In certain disclosed examples, the graft is secured to the atrium or ventricle side of the leaflet with an artificial cord implanted on an edge of the graft to improve coaptation. In some disclosed examples, the graft is secured to both leaflets to enable an edge-to-edge procedure similar to the Alfieri technique. Some examples of the disclosed methods including introducing the graft into the ventricle and guiding it into place using artificial cords previously implanted in the leaflet.

The application relates to the field of medical devices, in particular to a valve replacement system facilitating the capture of valve leaflets, comprising a valve support, a delivery system for delivering the valve support, the valve support being provided with a clamping arm, a linkage rod connected with the clamping arm, and an anchoring ring connected with the linkage rod, wherein the distal end of the linkage rod is detachably connected with the distal end of the delivery system, and the delivery system is operated to push or pull the linkage rod to the distal end, the linkage rod drives the clamping arm to fold to control the included angle between the clamping arm and the valve support; in the application, the opening and closing of the clamping arm can be controlled by operating the delivery system, the loading pipe diameter can be reduced, recovery can be realized, and intracardiac adjustment is facilitated, and the application has good clinical significance.