109results about "Venous valves" patented technology

The invention discloses an integrated interventional venous valve and a preparation method thereof. The integrated interventional venous valve comprises a valve stent, a valve leaflet and a skirt; the valve stent comprises a first annular grid stent, a second annular grid stent and a straight rod for connecting the first annular grid stent and the second annular grid stent; the skirt edge covers the inner and outer surfaces of the first annular grid bracket and the second annular grid bracket; the valve leaflet is arranged on the straight rod, one side of the valve leaflet is connected with the skirt edge, and the free surface of the other side of the valve leaflet is arc-shaped; according to the integrated interventional venous valve, the valve leaflet and the skirt edge cover the inner surface and the outer surface of the valve support, so that the valve support, the valve leaflet and the skirt edge do not need to be fixed through sewing, the problems of complexity and potential tearing risk of split type processing are solved, and by arranging the material and the structure of the valve support, the integral interventional venous valve can be manufactured. And the valve leaflet free surface has a bionic arc shape, so that the integrated interventional vein valve can adapt to the diameter change of a blood vessel.

Single and dual frame prosthetic venous valve assemblies, and catheter delivery systems and methods, are disclosed. A representative dual frame venous valve assembly includes an outer valve frame having a lumen and a frame and venous valve assembly arranged within the lumen. The frame and venous valve assembly, which also may be a stand- alone prosthetic venous valve assembly, includes an inner valve frame having a frame matrix forming lateral valve supports and valve commissure supports; a polymeric frame coating encapsulating the frame matrix; and a one or more polymeric leaflets integrally formed with or coupled to the polymeric frame coating, with each leaflet moveable between an open or partially open state and a closed or partially closed state. A delivery catheter includes keys or slots for insertion of locking tabs of the outer valve frame, and a deployment control handle for controlling deployment of the venous valve assembly.

A nested valved pipeline comprises an outer pipeline, a pipeline support on the inner wall of the outer pipeline and valve leaflets arranged on the pipeline support, 3-5 main ribs extend from the center of the root of each valve leaflet to the edge of each valve leaflet, secondary branch ribs are distributed among the main ribs, and the main ribs and the secondary branch ribs form reinforcing ribs for net-shaped supporting; the reinforcing ribs are embedded into the valve leaflets and are integrally formed with the valve leaflets; the root of the reinforcing rib extends to the attachment area of the valve leaflet and the pipeline support to form a T-shaped anchoring structure, an annular groove is designed in the edge, close to the root of the valve leaflet, of the pipeline support, the T-shaped anchoring structure of the reinforcing rib is embedded into the groove of the pipeline support, and a gap between the valve leaflet and the pipeline support is filled with biological glue; the pipeline support and the outer pipeline are combined and fixed in a physical and chemical mode. The valve leaflet falling risk is reduced, the fatigue life is prolonged, and the reflux and thrombus risks are reduced; due to the nested design of the outer pipeline and the pipeline support, the connecting difficulty between the valve leaflet and the outer pipeline is reduced, and 3D complex design and batch production of the valve leaflet are conveniently achieved.

A system for regulating blood flow through a blood vessel of a heart includes a valve and a controller. The valve includes an outer frame and two or more leaflets and is sized for placement at least partially within the blood vessel. The two or more leaflets are sized to overlap or contact each other in an expanded state. The controller is disposed outside the heart and transmits signals to the valve.

A stent including a tubular body formed of one or more interwoven wires, a first anchor member disposed adjacent the first open end of the stent, a second anchor member disposed adjacent the second open end of the stent, and at least one divider disposed between the first and second anchor members. The first and second anchor members and the divider extend radially outward from the tubular body to divide the tubular body into at least a first saddle region extending between the first anchor member and the divider and a second saddle region extending between the second anchor member and the divider.

Single and dual frame prosthetic venous valve assemblies, and catheter delivery systems and methods, are disclosed. A representative dual frame venous valve assembly includes an outer valve frame having a lumen and a frame and venous valve assembly arranged within the lumen. The frame and venous valve assembly, which also may be a stand-alone prosthetic venous valve assembly, includes an inner valve frame having a frame matrix forming lateral valve supports and valve commissure supports; a polymeric frame coating encapsulating the frame matrix; and a one or more polymeric leaflets integrally formed with or coupled to the polymeric frame coating, with each leaflet moveable between an open or partially open state and a closed or partially closed state. A delivery catheter includes keys or slots for insertion of locking tabs of the outer valve frame, and a deployment control handle for controlling deployment of the venous valve assembly.

An implantable prosthetic valve includes a radially collapsible and expandable annular frame having three commissure attachment posts and four rows of circumferential struts. The rows include a first row, a second row downstream of the first row, a third row downstream of the second row, and a fourth row downstream of the third row and defining an outflow end of the frame. Each row of circumferential struts includes angled struts arranged in a zig-zag pattern. A leaflet structure includes three leaflets forming three commissures, each commissure being connected to one of the commissure attachment posts only at locations along the commissure attachment posts between a first plane that is perpendicular to a longitudinal axis of the frame and intersects crowns of the third row of struts and a second plane that is perpendicular to the longitudinal axis and intersects crowns of the fourth row of struts.

A device may include a control element coupled to a valve disposed in an outer frame. The control element is configured to manipulate the valve between an unrestricted blood flow state and a restricted blood flow state. A device may include an actuation device including a linear actuator coupled to a control element of an implantable device, and a first magnet configured to induce rotation of the linear actuator. A control device communicatively coupled to the linear actuator includes a second magnet configured to generate a changing magnetic field pole direction to cause rotation of the first magnet either to tension the control element to position a valve of the implantable device in a restricted blood flow state or to release tension in the control element to position the valve in an unrestricted blood flow state.

A cardiac implant device may include a frame sized for placement at least partially within a blood vessel of a heart, the frame having a proximal end, a distal end, and a midsection, and comprising an outer frame and an inner frame. At least a portion of the inner frame is joined to the outer frame at the distal end of the frame and wherein the inner frame extends away from the outer frame at the midsection of the frame to form a gap between the inner frame and the outer frame. A device may include a sealing skirt extending at least partially along the inner frame and the distal end of the frame.

A flow restrictor for a blood vessel can include a frame positionable within a blood vessel, an inner cell, a leaflet, and a lumen through the flow restrictor. The lumen is defined at least in part by the leaflet. An inflow edge of the leaflet can be coupled to a movable junction of the inner cell, and an outflow edge of the leaflet can be coupled to an anchoring junction of the inner cell. The movable junction of the inner cell and the inflow edge of the leaflet can be configured to move axially in response to a first increase in a blood pressure within the blood vessel, and in response to the blood pressure within the blood vessel being within a first blood pressure range. The movable junction and the leaflet can be configured such that the lumen changes size when the movable junction moves.

A system for regulating blood flow through a blood vessel of a heart, the system comprising a valve comprising an outer frame and configured for placement at least partially within the blood vessel.

A cardiac implant device comprises a frame configured for placement at least partially within a blood vessel of a heart, a skirt configured to at least partially enclose the frame, and two or more arms extending from a distal end of the frame.

This invention relates to a valve prosthesis and a stent, the stent comprising a first stent. The first stent includes two first rod groups, and a first axial rod and a second axial rod connecting the two first rod groups and arranged along the axial direction of the stent. Each first rod group includes a plurality of first rods connected end-to-end and arranged in a W-shape. The first crests of the two first rod groups are arranged opposite each other, and the first troughs are arranged opposite each other. At least one or more of the two oppositely arranged first crests are connected by one or more first axial rods, and the two oppositely arranged first troughs are connected by one or more second axial rods. In this way, the arrangement density of the axial rods can be increased, thereby improving the radial support strength, so that it can be stably fixed at the location of the original valve; in addition, the enclosed quadrilateral structure can be easily bent under stress, that is, it will not affect the normal storage and folding of the stent.

This application generally relates to an transcatheter anti-reflux venous valve endoprosthesis system, including a replacement valve, a valve support frame, crimping system, and delivery system to treat patients with chronic venous insufficiency, and method for using such a system.

An implantable medical device for preventing backflow into a false lumen of dissection includes an elongate support member, an elongate flexible tubular valve member having a length, a proximal end, and an open distal end. At least one elongate resilient member extends at least partially along the length of the elongate flexible tubular valve member, the at least one elongate resilient member having a proximal end distal to the elongate support member, a distal end proximal to the open distal end of the elongate flexible tubular valve member, an elongated configuration, and a coiled configuration. The at least one elongate resilient member is unattached to the elongate support member. The at least one elongate resilient member, upon release from a constraining force, is configured to move from the elongated configuration to the coiled configuration thereby closing the open distal end of the elongate flexible tubular valve member.

The present disclosure relates to a method and a device for treating heart failure by normalizing elevated blood pressure in the left and right atria of a heart of a mammal. The present disclosure includes methods for creating and maintaining an opening in the atrial septum. Tools for making an opening and enlarging the opening are also disclosed. Use of the techniques and tools described herein prolongs the patency of an intra-atrial pressure relief opening.

A flow restrictor for a blood vessel can include a frame positionable within a blood vessel, an inner cell, a leaflet, and a lumen through the flow restrictor. The lumen is defined at least in part by the leaflet. An inflow edge of the leaflet can be coupled to a movable junction of the inner cell, and an outflow edge of the leaflet can be coupled to an anchoring junction of the inner cell. The movable junction of the inner cell and the inflow edge of the leaflet can be configured to move axially in response to a first increase in a blood pressure within the blood vessel, and in response to the blood pressure within the blood vessel being within a first blood pressure range. The movable junction and the leaflet can be configured such that the lumen changes size when the movable junction moves.

Medical systems, devices and methods for creation of autologous tissue valves within a mammalian body are disclosed. One example of a device for creating a valve flap from a vessel wall includes an elongate tubular structure having a proximal portion and a distal portion and a longitudinal axis; a first lumen having a first exit port located on the distal portion of the elongate tubular structure; a second lumen having a second exit port located on the distal portion of the elongate tubular structure; a recessed distal surface on the distal portion of the elongate tubular structure, wherein the recessed distal surface is located distally to the first exit port; and an open trough on the recessed distal surface extending longitudinally from the first exit port.

A transcatheter atrio-ventricular valve prosthesis (1) for functional replacement of a mitral or tricuspid atrio-ventricular valve (9) in a connection channel (18), having a circumferential connection channel wall structure (18'), between atrial (3) and ventricular (5) chambers of a heart (7), comprising an inner device (19) to be disposed in the interior of the connection channel (18), the inner device (19) having a circumferential support structure (21) which is radially expandable and having a valve (22) attached to the circumferential support structure (21), and an outer device (25) to be disposed on the exterior side of the connection channel (18), wherein the outer device (18) at least partly extends around the inner device in a radial distance to the inner device, wherein the circumferential support structure (21) of the inner device (19), and the outer device form a clamping mechanism for clamping the circumferential connection channel wall structure (18') of the connection channel (18) therebetween, wherein the outer device (25) comprises a circumferentially open ring in form of a helix.

An apparatus for crimping expandable prosthetic heart valves, the apparatus comprising jaws having a linear movement towards a centre, a stationary base including guidance slits facing the centre, and a rotating mechanical member rotating around the centre, the member including a spiral track, and three removable accessories consisting of: a handle level stop member 108 removably attached to the valve crimping device within an aperture formed in the housing 2, the handle stop member 108 calibrated to stop movement of the handle 5 when the proper aperture size is reached for a particular crimping operation; a crimped valve gauge 112 removably mounted on the base 4 and providing a tube 116 having a tapered throughbore with a minimum diameter that is equal to the minimum aperture diameter as limited by the stop member 108; and a balloon gauge removably mounted on the base 4 having an inner diameter calibrated to the desired maximum size of the expanding balloon used to deliver the prosthetic valve.

Devices, systems, and / or methods can treat aneurysms and / or other conditions, while providing compliance characteristics to fluid vessels. Examples of the present disclosure can include an implant device that includes a tubular structure with multiple first sections that deflect radially inward and that are separated by multiple second sections. The second sections can include lobes. The first sections can be configured to deflect radially outward based on radial / luminal pressure within a fluid vessel to provide a change in volume for the implant device.

The present invention belongs to the field of medical device technology, and specifically relates to a three-flap deep vein stent. A three-flap deep vein stent comprises: an opening and closing section; a covering film arranged on the opening and closing section; a supporting section, a hollow cylindrical structure, the inflow end of which is connected to the outflow end of the opening and closing section; a side leakage skirt, an annular structure with a diameter at the inflow end smaller than that at the outflow end, arranged on the outside of the supporting section; and an artificial leaflet, arranged on the inside of the opening and closing section. The present invention effectively prevents side leakage of blood by combining the design of the supporting section with the addition of a side leakage skirt and opening and closing the side leakage skirt.

A composite biomaterial having a continuous metal sheet with arcuate members that define a first fenestration pattern, and a polymer layer over at least one surface of the continuous metal sheet. The arcuate members elastically stretch to allow the continuous metal sheet to bend in more than one axis without buckling or wrinkling.

A nested valve conduit comprises an outer conduit, a conduit support on the inner wall of the outer conduit, and a valve leaf set arranged on the conduit support, wherein 3-5 main ribs extend from the center of the root of the valve leaf to the edge of the valve leaf, secondary branch ribs are distributed between the main ribs, and the main ribs and the secondary branch ribs constitute a mesh-shaped supporting reinforcing rib; the reinforcing rib is embedded in the interior of the valve leaf and integrally formed with the valve leaf; the root of the reinforcing rib extends to the attachment area of the valve leaf and the conduit support, forming a T-shaped anchoring structure; an annular groove is designed near the edge of the root of the valve leaf of the conduit support; the T-shaped anchoring structure of the reinforcing rib is embedded in the groove of the conduit support, and the gap between the valve leaf and the conduit support is filled with biological glue; and the conduit support and the outer conduit are combined and fixed through physical and chemical methods. The present application reduces the risk of valve leaf shedding, prolongs the fatigue life, and reduces the risk of regurgitation and thrombosis; the nested design of the outer conduit and the conduit support reduces the connection difficulty between the valve leaf and the outer conduit, facilitating the realization of 3D complex design and mass production of the valve leaf.

The present invention relates to a device for implantation into the heart of a mammal with longitudinal and rotational freedom of orientation and is intended for the treatment of tricuspid regurgitation. The device comprises a tubular stent implanted into the superior and inferior vena cava, as well as at least one valve that allows unidirectional blood flow into the right atrium.

This disclosure provides a tissue-engineered transcatheter vein valve and methods of making such a tissue-engineered transcatheter vein valve. Methods of making the valve include casting or molding a polymer into a tubular structure having a first end and a second end, where the first end of the tubular structure is cast or molded around a tubular support structure and where the second end of the tubular structure is cast or molded in the absence of the support structure; everting the polymer at the second end through the support structure; anchoring the second end of the tubular structure to the support structure at a first position and a second position, where the anchored first position and the anchored second position result in commissures, forming leaflets therebetween.

A prosthesis includes a tubular graft, a prosthetic valve component, an inflow stent, an outflow stent, and a plurality of body stents disposed between the inflow and outflow stents. Each stent is a sinusoidal patterned radially-expandable ring having a first set of crowns and a second set of crowns, with the first set of crowns disposed closer to an inflow end of the tubular graft than the second set of crowns. The prosthesis is configured to be resistant to backfolding and / or buckling during deployment thereof.

Ventricular catheters and other embodiments are provided. The catheter for shunting fluid includes a tip end, a first portion, and a second portion. The first portion is between and in fluid communication with the tip end and the second portion. The first portion is configured to have a tapered shape. The first portion includes multiple rows of holes.

Systems and methods for regulating fluid flow are provided. Specific examples are device or system (such as a catheter system) for regulating fluid flow including a tubing configured to allow fluid flow therethrough, an implantable valve, and an external actuating component. The implantable valve includes a regulating element arranged proximate to the tubing. In use, the actuating component (which may be external to the body of the subject or arranged inside the subject's body) is arranged proximate to the regulating element. The actuating component, which may be an external actuating component, is configured to manipulate a parameter associated with the regulating element.