Nested type pipeline with valve

Abstract

A nested valved pipeline comprises an outer pipeline, a pipeline support on the inner wall of the outer pipeline and valve leaflets arranged on the pipeline support, 3-5 main ribs extend from the center of the root of each valve leaflet to the edge of each valve leaflet, secondary branch ribs are distributed among the main ribs, and the main ribs and the secondary branch ribs form reinforcing ribs for net-shaped supporting; the reinforcing ribs are embedded into the valve leaflets and are integrally formed with the valve leaflets; the root of the reinforcing rib extends to the attachment area of the valve leaflet and the pipeline support to form a T-shaped anchoring structure, an annular groove is designed in the edge, close to the root of the valve leaflet, of the pipeline support, the T-shaped anchoring structure of the reinforcing rib is embedded into the groove of the pipeline support, and a gap between the valve leaflet and the pipeline support is filled with biological glue; the pipeline support and the outer pipeline are combined and fixed in a physical and chemical mode. The valve leaflet falling risk is reduced, the fatigue life is prolonged, and the reflux and thrombus risks are reduced; due to the nested design of the outer pipeline and the pipeline support, the connecting difficulty between the valve leaflet and the outer pipeline is reduced, and 3D complex design and batch production of the valve leaflet are conveniently achieved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and more particularly to a nested valved conduit. Background Art

[0002] As a key implantable device for treating congenital heart disease, aortic valve disease and large blood vessel reconstruction, the structural design and manufacturing process of valved conduits directly affect clinical efficacy and patient prognosis.

[0003] Currently, the polymer valved conduits commonly used in clinical practice still have the following significant technical limitations in their preparation and application: Existing valved conduits are often manufactured using a flat film-forming and two-dimensional cutting process. Polymer materials are cast or injection-molded into a flat film, which is then cut into pre-defined leaflets using a mold. This process results in uneven stress distribution during the opening and closing of the leaflets, which can easily cause localized tearing or wrinkling. This can lead to functional degradation after long-term use, increasing radial displacement of the leaflets and reducing the hemodynamic stability and long-term durability of the valved conduit.

[0004] Therefore, the problems existing in the prior art need to be further improved and developed. Summary of the Invention

[0005] (1) Purpose of the invention: In order to solve the problems existing in the above-mentioned prior art, the purpose of the present invention is to provide a nested valved conduit.

[0006] (II) Technical Solution: To solve the above-mentioned technical problems, the present technical solution provides a nested valved conduit, comprising an outer conduit, a conduit support on the inner wall of the outer conduit, and a valve leaflet mounted on the conduit support, wherein 3-5 main ribs extend from the center of the valve leaflet root toward the valve leaflet edge, and secondary branch ribs are distributed between the main ribs. The main ribs and secondary branch ribs constitute a mesh-like support reinforcement rib; the reinforcement ribs are embedded in the interior of the valve leaflet and are integrally formed with the valve leaflet; The root of the reinforcing rib extends to the attachment area of ​​the leaflet and the pipe bracket to form a T-shaped anchoring structure. An annular groove is designed on the edge of the pipe bracket near the root of the leaflet. The T-shaped anchoring structure of the reinforcing rib is embedded in the groove of the pipe bracket, and the gap between the leaflet and the pipe bracket is filled with biological glue.

[0007] The nested valved conduit has a main rib width of 0.8 mm-1.2 mm and a thickness of 0.5 mm-0.8 mm; a secondary branch rib width of 0.3 mm-0.5 mm and a thickness of 0.2 mm-0.4 mm.

[0008] In the nested valved pipe, the material of the main reinforcement is polyetheretherketone or carbon fiber reinforced polylactic acid.

[0009] In the nested valved conduit, the spacing between the main ribs of the reinforcing ribs needs to be greater than three times the thickness of the valve leaflet.

[0010] The nested valved conduit has a rectangular cross-section at the root of the reinforcement rib of the leaflet, which is 1.2 mm wide and 0.2 mm thick; the cross-section of the edge of the leaflet gradually becomes a trapezoid, which is 0.5 mm wide and 0.1 mm thick, and the carbon fiber content in the carbon fiber reinforced polylactic acid material is reduced from 30% to 10%.

[0011] The nested valved conduit is characterized in that a cylindrical memory alloy wire is embedded in the T-shaped anchoring structure at the root of the reinforcing rib, and a polylactic acid-hydroxyacetic acid copolymer nanofiber layer is wrapped around the wire surface of the memory alloy wire. The wire surface of the memory alloy wire and the lactic acid-hydroxyacetic acid copolymer nanofiber layer form a damping layer.

[0012] The nested valved pipe, wherein the mass of the damping layer at the root of the reinforcing rib is 0.2g-0.3g.

[0013] In the nested valved conduit, the valve leaflets and the conduit support are combined together by dipping, sewing, or injection molding.

[0014] The nested valved conduit described herein is provided with sinus protrusions in the form of hemispherical or pear-shaped protrusions that match the number of leaflets at circumferential intervals on the outer wall of the outer conduit, and the height of the sinus protrusions is 1 / 5-1 / 3 of the diameter of the outer conduit; the bottom of the sinus protrusions smoothly transitions to the outer wall of the outer conduit.

[0015] The nested valved conduit described herein has an outer wall of the outer conduit that is a smooth straight cylinder.

[0016] In the nested valved conduit, the outer conduit and the conduit support are fixedly connected by chemical or physical methods.

[0017] The nested valve-bearing tube, wherein the reinforcement rib of the leaflet is the elastic modulus of the leaflet, which changes gradually from the root of the leaflet to the edge of the leaflet, with the elastic modulus of the leaflet root segment being 1.2 GPa, the elastic modulus of the leaflet middle segment being 1.05 GPa, and the elastic modulus of the leaflet edge segment being reduced to 0.8 GPa.

[0018] The nested valved conduit has an edge length of 33mm-37mm, a root chord length of 23-27mm, and a radius of 17mm-18mm.

[0019] (III) Beneficial Effects: The present invention provides a nested valved conduit, which achieves the following technical effects: 1. Enhanced structural stability: The mesh reinforcement ribs are integrated with the valve leaflets, combined with a T-shaped anchoring structure embedded in the stent groove and filled with bio-glue, to enhance the leaflet's tear resistance and fixation strength, reducing the risk of dislodging. 2. Gradient mechanical properties: Gradient changes in rib size, material composition, and elastic modulus simulate the mechanical properties of natural valves, reduce stress concentration, and extend fatigue life; 3. Precise functional regulation: Titanium alloy microbeads and sinus protrusions work synergistically to optimize leaflet coaptation accuracy and hemodynamics, reducing the risk of regurgitation and thrombosis; 4. Improved biocompatibility: The PLGA nanofiber damping layer on the surface of the memory alloy wire cushions impact, and the polyetheretherketone / carbon fiber reinforced polylactic acid material combines high strength and biosafety, suitable for long-term implantation needs. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 This is a perspective structural diagram of a nested valved pipe according to the present invention; Figure 2 This is a schematic diagram of the internal structure of a nested valved pipe according to the present invention; Figure 3 This is a schematic diagram of a top view of a nested valved pipe according to the present invention; Figure 4 This is a structural schematic diagram of a preferred embodiment of a reinforcing rib in a nested valved pipe according to the present invention; Figure 5 This is a schematic structural diagram of a preferred embodiment of a titanium alloy micro-bead in a nested valved pipe of the present invention; 100-external pipe; 200-pipe support; 300 leaflet; 301-main rib; 302-secondary branch rib; 303-titanium alloy microbead. DETAILED DESCRIPTION

[0021] The present invention is further described in detail below in conjunction with preferred embodiments. More details are set forth in the following description to facilitate a full understanding of the present invention. However, the present invention can obviously be implemented in a variety of other ways different from the description. Those skilled in the art can make similar generalizations and deductions based on actual application situations without violating the connotation of the present invention. Therefore, the scope of protection of the present invention should not be limited by the content of this specific embodiment.

[0022] The accompanying drawings are schematic diagrams of embodiments of the present invention. It should be noted that the drawings are merely examples and are not drawn to scale, and should not be used to limit the actual scope of protection claimed in the present invention.

[0023] The present invention provides a nested valved conduit, such as Figure 1-3As shown, it comprises an outer pipe 100, a pipe support 200 on the inner wall of the outer pipe 100, and a leaflet 300 arranged on the pipe support 200. The leaflet 300 is a polymer leaflet. The end of the leaflet 300 connected to the pipe support 200 is the root of the leaflet 300, and the end of the leaflet 300 away from the pipe support 200 is the edge of the leaflet 300. 3-5 main ribs 301 extend from the center of the root of the leaflet 300 to the edge of the leaflet 300. Secondary branch ribs 302 are distributed between the main ribs 301. The main ribs 301 and the secondary branch ribs 302 constitute the reinforcement ribs of the mesh support. The reinforcement ribs are embedded in the interior of the leaflet 300 and are integrally formed with the leaflet 300.

[0024] like Figure 4 As shown, the reinforcing ribs are a mesh structure composed of main ribs 301 and secondary branch ribs 302. The secondary branch ribs 302 serve as an auxiliary support structure for the reinforcing ribs, enabling the main ribs 301 and the secondary branch ribs 302 to bear force in coordination, thereby enhancing the deformation resistance of the leaflet 300 and optimizing the stress transfer path through the distribution of the secondary branch ribs 302 to achieve uniform stress transfer, thereby avoiding the problem of decreased flexibility of the leaflet 300 or increased blood flow resistance due to excessive thickness.

[0025] The outer tube 100 and the tube support 200 can be straight cylindrical or cylindrical with a sinus protrusion. The outer tube 100 is made of a flexible elastic polymer material and has a certain degree of elasticity. The outer diameter of the tube support 200 can be equal to or slightly larger than the inner diameter of the outer tube 100. The outer tube 100 and the tube support 200 can be fixedly connected by suturing, chemical adhesion, or physical methods. The leaflets 300 and the tube support 200 can be fixedly connected by dipping, sewing, injection molding, etc.: first, the leaflets 300 are formed on the tube support 200 by dipping or injection molding, or the cut leaflets 300 are fixed by suturing, and then the tube support 200 is inserted axially into the interior of the outer tube 100 and fixed by suturing, chemical adhesion, or physical methods. The structural design of the nested valve-bearing tube reduces the difficulty of combining the leaflets 300 with the outer tube 100, and at the same time facilitates the production of leaflets 300 with complex three-dimensional geometric structures by dipping, injection molding, etc.

[0026] The root of the reinforcing rib refers to the rib near one end of the pipe support 200. The root of the reinforcing rib extends to the attachment area between the leaflets 300 and the pipe support 200, forming a T-shaped anchoring structure. The pipe support 200 has an annular groove at the root edge near the leaflets 300. The T-shaped anchoring structure of the reinforcing rib is embedded in the groove of the pipe support 200, and the gap between the leaflets 300 and the support is filled with bio-glue.

[0027] Preferably, the inner wall of the outer tube 100 is provided with three leaflets 300, the edge length of each leaflet 300 is 33 mm to 37 mm, the root chord length of each leaflet 300 is 23 mm to 27 mm, and the radius of each leaflet 300 is 17 mm to 18 mm. The root chord lengths of the three leaflets 300 are close to the circumference of the inner wall of the tube.

[0028] In the present invention, the main ribs 301 preferably have a width of 0.8mm-1.2mm and a thickness of 0.5mm-0.8mm. The secondary branch ribs 302 have a width of 0.3mm-0.5mm and a thickness of 0.2mm-0.4mm. The distance between the main ribs 301 of the reinforcing ribs is greater than three times the thickness of the leaflet 300. The main ribs 301 are preferably made of polyetheretherketone (PEEK) or carbon fiber reinforced polylactic acid (CFR-PLA).

[0029] The distribution density of the secondary branch ribs 302 varies gradiently along the radial direction of the leaflet 300. For example, the root segment is 0-1 / 3 of the length away from the root of the leaflet 300, and the branch rib spacing is 1.5mm-2mm; the middle segment is 1 / 3-2 / 3 of the length away from the root of the leaflet 300, and the branch rib spacing is 2mm-3mm; the edge segment is 2 / 3 of the length away from the root of the leaflet 300 to the free edge of the leaflet 300, and the branch rib spacing is 3mm-4mm; and the angle between the secondary branch ribs 302 and the main ribs 301 gradually decreases from 45° in the root segment to 15° in the edge segment, forming a bionic support structure with dense roots and sparse edges.

[0030] The root of the leaflet 300 has a rectangular cross-section, with a circumferential width of 1.2 mm and a radial thickness of 0.2 mm. The cross-section of the edge of the leaflet 300 gradually becomes a trapezoidal shape, with a width of 0.5 mm and a thickness of 0.1 mm. The carbon fiber content of the carbon fiber-reinforced polylactic acid material is reduced from 30% to 10%.

[0031] The cross section of the leaflet 300 transitions from a rectangular shape at the root to a trapezoidal shape at the edge through thickness gradient and geometric optimization. The specific structural features are as follows: First, the rectangular cross-section of the root of the leaflet 300: the root of the leaflet 300 is also the fixed end where the leaflet 300 is connected to the outer tube 100. The leaflet 300 has a circumferential width of 1.2 mm, a radial thickness of 0.2 mm, and a height (axial length) of 5 mm. The cross-section is an equal-thickness rectangle with parallel and equal-length sides on the upper and lower bases, and vertical sides to ensure a rigid connection with the rectangular cross-section of the reinforcement rib to provide sufficient fixing strength. The elastic modulus of the root of the leaflet 300 is approximately 1.2 GPa.

[0032] Secondly, the middle transition section of the leaflet 300: when the root of the leaflet 300 extends toward the edge of the leaflet 300, the lower base of the cross section close to the inner wall of the outer tube 100 maintains the same length, and the upper base on the free edge side of the leaflet 300 gradually shortens. At the same time, the overall radial thickness, that is, the height of the leaflet 300 linearly decreases to form a right-angled trapezoidal structure. For example, the radial thickness of the leaflet 300 linearly decreases from 0.2 mm to 0.1 mm, and the circumferential width shrinks from 1.2 mm to 0.5 mm.

[0033] Finally, the trapezoidal cross-section of the leaflet 300's edge forms an isosceles trapezoid at the free edge of the leaflet 300, with a radial thickness of 0.1mm and a circumferential width of 0.5mm. The waist edges are symmetrically inclined at angles of approximately 15°-30°, further reducing the edge thickness. The center of gravity of the cross-section is offset toward the bottom edge, ensuring flexible deformation of the edge during opening and closing.

[0034] By gradually reducing the cross-sectional area from the root to the edge, and by distributing the reinforcing ribs only at the root of the leaflet 300, a gradient attenuation of the elastic modulus is achieved, while ensuring the flexibility of the edge and the structural stability of the root.

[0035] The reinforcing ribs provided on the leaflet 300 and the cross-section of the root of the leaflet 300 are rectangular, and the cross-section of the edge of the leaflet 300 gradually becomes a trapezoidal setting, so that the elastic modulus of the leaflet 300 changes gradually from the root of the leaflet 300 to the edge of the leaflet 300, with the elastic modulus of the root segment of the leaflet 300 being 1.2 GPa, the elastic modulus of the middle segment of the leaflet 300 being 1.05 GPa, and the elastic modulus of the edge segment of the leaflet 300 being reduced to 0.8 GPa.

[0036] A preferred embodiment of a nested valved conduit, wherein a cylindrical memory alloy wire is embedded in the T-shaped anchoring structure at the root of the reinforcing rib, and a polylactic-co-glycolic acid copolymer (PLGA) nanofiber layer is wound around the filament surface of the memory alloy wire. The filament surface of the memory alloy wire and the lactic-co-glycolic acid copolymer nanofiber layer form a damping layer. The damping layer at the root of the reinforcing rib has a mass of 0.2g-0.3g. A controllable mass damping structure is integrated at the root of the reinforcing rib, which utilizes inertial resistance and vibration energy dissipation to further reduce the radial displacement of the leaflet 300 during opening and closing, controlling the radial displacement to ≤0.1mm while avoiding increasing the transvalvular pressure difference or the risk of thrombosis. The reinforcing rib has an integrated elastic damping structure at the root, which dissipates vibration energy through material deformation and suppresses high-frequency radial displacement.

[0037] The porosity of the nanofiber layer is distributed in a gradient along the axial direction of the memory alloy wire: the porosity near the end of the T-shaped anchoring structure is 60%-70%, which is the high elastic deformation zone of the nanowire fiber layer, and the porosity away from the end of the T-shaped anchoring structure is 30%-40%, which is the high energy dissipation zone of the nanofiber layer; and the nanofiber diameter gradually changes from 500nm to 200nm. Through the coordinated regulation of porosity and fiber diameter, the energy dissipation rate of the damping layer at a vibration frequency of 0.5Hz-5Hz is increased to ≥85%. The present invention breaks through the traditional uniform damping layer design and uses a gradient pore structure to achieve functional zoning of rigid fixation and flexible energy dissipation, achieving the technical effect of compatibility of high damping and low elastic modulus, and increasing the high-frequency vibration attenuation amplitude of the leaflet 300 by 40%.

[0038] The preferred embodiment of the nested valved conduit of the present invention is as follows Figure 5 As shown, multiple titanium alloy micro-beads 303 are embedded at the edge of each leaflet 300. By arranging high-density mass blocks of titanium alloy micro-beads 303 at the edge of the leaflet 300, the inertial force of the titanium alloy micro-beads 303 is used to offset the radial vibration caused by blood flow impact.

[0039] Three to four titanium alloy micro-beads 303 are embedded circumferentially at intervals of 1 mm to 2 mm from the edge of the leaflet 300 . The titanium alloy micro-beads 303 have a diameter of 0.8 mm to 1.2 mm and a single bead mass of 0.05 g to 0.1 g.

[0040] In a preferred embodiment of the leaflet 300 described in the present invention, the leaflet 300 is divided into three equal parts along the direction from the root of the leaflet 300 to the edge of the leaflet 300, including a root segment, a middle segment and an edge segment, and titanium alloy microbeads 303 are arranged at a spacing of 2mm-3mm along the edge direction of the leaflet 300 in the junction area between the middle segment and the edge segment.

[0041] The present invention preferably provides a contact zone where the free edges of adjacent leaflets 300 fit together, and titanium alloy micro-beads 303 are arranged at intervals of 5mm-6mm along the edges of the leaflets 300. The free edges of the leaflets 300 are the apposition zones, which are the sealing contact zones when the leaflets 300 are closed. The integrity of the apposition zones is key to preventing regurgitation. Research in the present invention has found that the vibration-prone areas are concentrated in the middle of the leaflets 300, away from the free edges of the leaflets 300. The differentiated distribution strategy of the titanium alloy micro-beads 303: 2-3mm spacing in the middle and 5-6mm spacing in the apposition zones, can effectively suppress vibration and ensure sealing.

[0042] In the preferred embodiment of the present invention, the titanium alloy microbeads 303 have 0.1 mm deep annular grooves on their surfaces. Microbead positioning grooves are pre-set in the leaflet 300 edge region of the leaflet 300 mold. During injection molding, the titanium alloy microbeads 303 are precisely embedded in the molten polymer material, forming a mechanical interlocking structure after cooling. The 0.1 mm deep annular grooves on the titanium alloy microbeads 303 of the present invention enhance the bond between the titanium alloy microbeads 303 and the leaflet 300 material.

[0043] The outer wall of the outer tube 100 of the present invention is provided with hemispherical or pear-shaped sinus protrusions spaced circumferentially to match the number of leaflets 300. The height of the sinus protrusions is 1 / 5 to 1 / 3 of the diameter of the outer tube 100. The bottom of the sinus protrusions smoothly transitions to the outer wall of the outer tube 100. The sinus protrusions on the outer wall of the outer tube 100 prevent deformation of the outer tube 100 from interfering with the movement of the leaflets 300, maintaining hemodynamic stability. If the outer tube 100 expands or contracts radially due to blood pressure fluctuations, it will cause the roots of the leaflets 300 to displace synchronously, resulting in an increase in the opening and closing time difference of the leaflets 300 and poor valve orifice coaptation, thereby causing blood reflux. The present invention can reduce the displacement through the rigid support of the sinus protrusion, and control the radial displacement within the range of ≤0.2mm, ensuring that the movement trajectory of the leaflets 300 is only driven by blood flow pressure rather than deformation of the outer tube 100, and can simulate the hemodynamic characteristics of the human aortic sinus, forming a vortex buffer zone when the leaflets 300 open and close, reducing the impact of blood flow on the free edge of the leaflets 300, and reducing the incidence of thrombosis to less than 0.5% / year.

[0044] The nested valve-bearing pipe of the present invention realizes uniform stress transmission and improves the mechanical properties and durability of the leaflet 300 by setting reinforcing ribs: the main ribs 3010.8mm-1.2mm wide and the secondary branch ribs 3020.3mm-0.5mm wide form a mesh structure.

[0045] The Leaflet 300's cross-section transitions from a rectangular 1.2mm wide x 0.2mm thick at the base to a trapezoidal 0.5mm wide x 0.1mm thick at the edge. This gradual change in Leaflet 300's cross-section, combined with a material gradient that reduces the carbon fiber content from 30% to 10%, achieves a smooth decrease in elastic modulus from 1.2GPa at the base to 0.8GPa at the edge. This seamlessly combines rigid fixation at the base of Leaflet 300 (radial displacement ≤ 0.1mm) with flexible opening and closing at the edge (deformation increased by 35%), resolving the technical conflict between rigid fixation and flexible movement.

[0046] The circumferential matching design of the three leaflets 300 with an edge length of 33mm-37mm and a root chord length of 23mm-27mm, combined with the sealing compensation of the trapezoidal edge bevel angle of 15°-30°, controls the regurgitation rate to ≤3%. At the same time, the edge thickness of the leaflet 300 is thinned to 0.1mm, and the transvalvular pressure difference is reduced to 12mmHg, which is 28% lower than traditional products, avoiding excessive right heart load after surgery.

[0047] A PLGA nanofiber membrane is wrapped around the surface of the memory alloy wire in the T-shaped anchoring structure at the root of the reinforcement rib to form a damping layer with a mass of 0.2g-0.3g. Combined with the inertial force offset effect of the edge titanium alloy microbeads 303 with a diameter of 0.8mm-1.2mm and a spacing of 2mm-6mm, the high-frequency vibration amplitude of the leaflet 300 is reduced by 65%, and the radial displacement is controlled to ≤0.1mm. The synergistic vibration reduction of the damping layer and the titanium alloy microbeads 303 avoids wear or poor alignment of the leaflet 300 due to vibration.

[0048] The above content is an explanation of the preferred embodiments of the present invention, which can help those skilled in the art to more fully understand the technical solutions of the present invention. However, these embodiments are merely illustrative, and it cannot be determined that the specific implementation methods of the present invention are limited to the description of these embodiments. For those skilled in the art of the present invention, without departing from the concept of the present invention, several simple deductions and transformations can be made, which should be deemed to fall within the scope of protection of the present invention.

Claims

1. A nested valved conduit, comprising an outer conduit, a conduit support on the inner wall of the outer conduit, and a valve leaflet arranged on the conduit support, characterized in that: 3-5 main ribs extend from the center of the leaflet root toward the leaflet edge, and secondary branch ribs are distributed between the main ribs. The main ribs and secondary branch ribs constitute reinforcement ribs for mesh support; the reinforcement ribs are embedded in the leaflet and are integrally formed with the leaflet; The root of the reinforcing rib extends to the attachment area of ​​the leaflet and the pipe bracket to form a T-shaped anchoring structure. An annular groove is designed on the edge of the pipe bracket near the root of the leaflet. The T-shaped anchoring structure of the reinforcing rib is embedded in the groove of the pipe bracket, and the gap between the leaflet and the pipe bracket is filled with biological glue.

2. The nested valved conduit according to claim 1, characterized in that: The main rib has a width of 0.8 mm to 1.2 mm and a thickness of 0.5 mm to 0.8 mm. The secondary branch rib has a width of 0.3 mm to 0.5 mm and a thickness of 0.2 mm to 0.4 mm.

3. The nested valved conduit according to claim 1, characterized in that: The material of the main reinforcement is polyetheretherketone or carbon fiber reinforced polylactic acid.

4. The nested valved conduit according to claim 1, characterized in that: The distance between the main ribs of the reinforcing ribs must be greater than 3 times the thickness of the leaflet.

5. The nested valved conduit according to claim 3, characterized in that: The cross-section of the root of the leaflet's reinforcement rib is rectangular, with a width of 1.2 mm and a thickness of 0.2 mm; the cross-section of the leaflet's edge gradually becomes a trapezoid, with a width of 0.5 mm and a thickness of 0.1 mm. At the same time, the carbon fiber content in the carbon fiber reinforced polylactic acid material is reduced from 30% to 10%.

6. The nested valved conduit according to claim 1, characterized in that: A cylindrical memory alloy wire is embedded in the T-shaped anchoring structure at the root of the reinforcing rib. The surface of the memory alloy wire is wrapped with a polylactic acid-glycolic acid copolymer nanofiber layer. The surface of the memory alloy wire and the lactic acid-glycolic acid copolymer nanofiber layer form a damping layer.

7. The nested valved conduit according to claim 6, characterized in that: 2g-0.3g。 The mass of the damping layer at the root of the reinforcement rib is 0. 2g-0.3g.

8. The nested valved conduit according to claim 1, characterized in that: The leaflets and the pipeline support are combined together by dipping, sewing, and injection molding.

9. The nested valved conduit according to claim 1, characterized in that: The outer wall of the outer tube is provided with hemispherical or pear-shaped sinus protrusions at intervals along the circumference and matching the number of leaflets. The height of the sinus protrusion is 1 / 5-1 / 3 of the diameter of the outer tube; the bottom of the sinus protrusion smoothly transitions with the outer wall of the outer tube.

10. The nested valved conduit according to claim 1, characterized in that: The outer wall of the outer pipe is in a smooth straight cylindrical shape.

11. The nested valved conduit according to claim 1, characterized in that: The outer pipe and the pipe support are fixedly connected by chemical or physical methods.

12. The nested valved conduit according to claim 1, wherein: The reinforcement rib of the leaflet is the elastic modulus of the leaflet, which changes gradually from the root of the leaflet to the edge of the leaflet. The elastic modulus of the leaflet root segment is 1.2GPa, the elastic modulus of the leaflet middle segment is 1.05GPa, and the elastic modulus of the leaflet edge segment is reduced to 0.8GPa.

13. The nested valved conduit according to claim 1, characterized in that: The edge length of a single leaflet is 33mm-37mm, the root chord length of the single leaflet is 23-27mm, and the radius of the single leaflet is 17mm-18mm.

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