44 results about "Atrial septum" patented technology

The application relates to a degradable occluder implantation system, which comprises an occluder body composed of an upper disc, a lower disc and a hollow waist, the upper disc, the lower disc and the waist are formed by weaving wires made of degradable materials, an upper connecting piece comprises an upper connecting part and an upper combining part, a lower connecting piece comprises a lower connecting part and a lower combining part, a conveying device comprises a core connecting piece, a sleeve connecting piece and an outer sheath, the sleeve connecting piece is coaxially movably arranged in the outer sheath, a channel is formed in the middle of the sleeve connecting piece, the core connecting piece is movably arranged in the channel, the upper end of the core connecting piece is detachably connected with the upper connecting part, and the sleeve connecting piece is detachably connected with the lower connecting part. The application pulls the upper connecting piece to move in the inner side of the waist through the core connecting piece, so that the upper connecting piece and the lower connecting piece are close to and combined together, the upper disc and the lower disc are unfolded and attached to the atrial septum, the problem of poor occlusion effect of the degradable occluder is solved, and the risk of thrombus shedding is reduced.

This invention relates to the field of congenital heart disease treatment technology, and discloses the application of sapropterin in the prevention and treatment of bisphenol fluorene-induced congenital heart disease in fetuses. The congenital heart disease includes cardiac structural defects, heart failure, or cardiomyocyte lesions, specifically selected from ventricular septal defects, atrial septal defects, tetralogy of Fallot, myocardial hypertrophy, decreased cardiac ejection fraction, decreased short-axis contraction rate, cardiomyocyte ferroptosis, myocardial tissue inflammatory infiltration, or myocardial collagen fibrosis. Sapropterin is used as a direct supplement to biological tetrahydropterin (BH4). Through exogenous intervention, it precisely reverses the endogenous BH4 deficiency caused by bisphenol fluorene exposure, restores the expression of GTP cyclase 1 (GCH1) and the dynamic balance of RNA m6A, and upregulates the level of YTH domain family protein 2 (YTHDF2), thereby blocking ferroptosis signal transduction, reducing oxidative stress and inflammatory response, and inhibiting the process of myocardial tissue fibrosis at the molecular level.

The invention relates to an atrial septal stoma system, and belongs to the technical field of medical instruments. According to the application, the cutter movably penetrating through the sheathing canal body is arranged, the pushing rod of the capturing device movably penetrates through the cutter, and the traction part of the storage device movably penetrates through the pushing rod, so that the atrial septum tissue can be captured through the capturing device, and the capturing device and the captured atrial septum tissue can be tightened in the storage cavity of the capturing device through the storage device; in addition, the captured atrial septum tissue can be cut through the cutter to form a stoma, and the cut atrial septum tissue is bound through cooperation of the capturing claw and the storage part, so that the cut tissue can be conveniently withdrawn out of the body along with the system, and the cut tissue is prevented from falling off and being left in the atrium.

The present application relates to a kind of tissue defect plugging device and tissue defect plugging device.Tissue defect plugging device includes plugging device body, plugging device body is memory material.When plugging device body is in natural relaxed state, all clamping ring is in the same plane, or, adjacent two clamping ring is provided with gap in the direction of straight line perpendicular to its plane, can produce original shape restoring torque, so that the first atrial septum and the second atrial septum produce mutual close tendency, and then make the first atrial septum and the second atrial septum mutually close and close, finally reach the purpose of closing foramen ovale, plugging effect is better, while operation is relatively simple.In addition, because the caliber of clamping ring is different, so as to cancel the flow blocking film, simple structure, also obtain the effect of plugging foramen ovale;In addition, using the above structure design form, the metal material implanted in body is less, can avoid the complication of thrombosis, i.e. not easy to cause adverse reaction.

The application discloses an ostomy device and an ostomy system, and relates to the technical field of medical devices, in particular to an ostomy device and an ostomy system. The ostomy device comprises a puncture assembly, a cutting assembly and a sheath tube assembly. The puncture assembly comprises a mandrel and a puncture part, and the puncture part is arranged at the distal end of the mandrel. The cutting assembly is arranged around the mandrel and at the proximal end of the puncture part. The sheath tube assembly is arranged around the puncture assembly and the cutting assembly, and the distal end of the sheath tube assembly is provided with a receiving tube section. The opening caliber of the distal end of the receiving tube section is adjustable. The distal end of the sheath tube assembly of the ostomy device is provided with the receiving tube section, the opening caliber of the distal end of the receiving tube section is adjustable, and the distal end can form an outwardly expanding horn-shaped opening. When the cutting assembly cuts the atrial septum tissue from the distal end to the proximal end, the receiving tube section can receive the cut tissue, so that the cut tissue cannot escape into the blood circulation and cause thrombosis.

This application relates to a coronary sinus and left atrium shunt system, belonging to the field of medical device technology. The system described in this application, by setting up a puncture component and a shunt component including a cutter, allows for the cutting of a portion of myocardial tissue between the coronary sinus and the left atrium, forming a shunt orifice. This establishes a shunt channel between the coronary sinus and the left atrium, effectively avoiding the embolism risk associated with atrial septal shunts and improving coronary artery blood perfusion, potentially benefiting myocardial recovery.

The invention provides a mitral valve clip operation simulator which comprises a bottom plate, and a first side of the bottom plate is provided with a first storage groove and a second storage groove; the first module is provided with an atrial septum simulation part and a mitral valve simulation part, and the first module is arranged on the bottom plate in the mode that the first module can be switched between an unfolded state and a folded state; the second module is provided with a lower cavity tube used for simulating the inferior vena cava, and the second module is arranged on the bottom plate in a mode of being capable of being switched between an unfolded state and a folded state; when the first module is in an unfolded state, the atrial septum simulation part and the mitral valve simulation part protrude out of the bottom plate, and the positions of the atrial septum simulation part and the mitral valve simulation part form an analogue simulation position; when the second module is in an unfolded state, the lower cavity tube protrudes out of the bottom plate to form a surgical instrument access path; when the first module is in the folded state, the first module is integrally contained in the first containing groove, and when the second module is in the folded state, the second module is integrally contained in the second containing groove.

The invention discloses a double-disc-shaped integrally-formed degradable heart atrial septum foramen ovale plugging device which comprises a first disc part, a second disc part and a plugging part, the first disc part and the second disc part are connected to the two axial ends of the plugging part, and the first disc part, the second disc part and the plugging part are integrally-formed pieces and are degradable pieces; the first disc part and the second disc part are elastic pieces capable of automatically restoring to original shapes, and the first disc part and the second disc part are arranged in parallel. The plugging device is an integrally-formed degradable part and provides a temporary bridge for self-repairing of the heart, so that self cell tissues can climb and grow, and then the plugging device is degraded and absorbed in the body. Long-term complications and potential safety hazards caused by metal remaining in a human body can be avoided, the plugging device is high in structural integrity, the degradation rate of the plugging device in the human body is uniform, no structural disintegration risk exists, all the defects of an existing plugging device of a woven structure can be overcome, and surgical operation can be simplified.

The application provides an atrial septum puncture needle sheath system, and relates to the technical field of medical devices, to solve the problem that the existing technology lacks feedback to the operator when puncturing through the foramen ovale. The atrial septum puncture needle sheath system comprises an expander outer tube, a handle shell, an inner needle assembly, and a pushing mechanism and a pull rod installed in the handle shell. The expander outer tube is connected to the front end of the handle shell. The rear end of the inner needle assembly is arranged in the handle shell, and the front end of the inner needle assembly extends into the expander outer tube. The rear end of the inner needle assembly is movably connected to the front end of the pull rod through a first elastic member. When the front end of the inner needle assembly pierces the puncture site, the first elastic member pushes the inner needle assembly to move relative to the pull rod towards the front end of the pull rod and triggers a feedback mechanism. The atrial septum puncture needle sheath system can trigger the feedback mechanism when the puncture site is pierced, so that the operator can perceive that the inner needle assembly has pierced the puncture site, and further advancement is avoided, thereby improving the safety of operation.

The utility model discloses a double-disc-shaped integrally-formed degradable heart atrial septum foramen ovale plugging device which comprises a first disc part, a second disc part and a plugging part, the first disc part and the second disc part are connected to the two axial ends of the plugging part, and the first disc part, the second disc part and the plugging part are integrally formed pieces. And the first disc part and the second disc part are elastic pieces capable of automatically restoring to original shapes. At least part of at least one of the first disc part and the second disc part is an inverted-cone-shaped ring, and the inverted-cone-shaped ring extends in the direction away from the center of the double-disc-shaped integrally-formed degradable heart atrial septal foramen ovale plugging device from the center to the edge. The plugging device is an integrally-formed degradable part, is used for self cell tissues to climb and grow, and then is degraded and absorbed in vivo. All the defects of an existing plugging device of a woven structure can be overcome, and surgical operation can be simplified. And moreover, the condition that the first disc part or the second disc part hinders the atrial septum foramen ovale of the heart can be reduced, and the working reliability is improved.

The application discloses a myocardial biopsy forceps, and relates to the technical field of medical devices, which comprises an operating handle and a sampling assembly, the operating handle is used for controlling the sampling assembly to extract atrial septum tissue through a sheath tube and a spring tube; the sampling assembly comprises a forceps head and a ring-shaped cutting edge, the ring-shaped cutting edge is fixedly connected with one end of the sheath tube, the other end of the sheath tube is connected with the operating handle, the spring tube is movably arranged in the sheath tube, one end of the spring tube is fixedly connected with the forceps head, and the other end of the spring tube is connected with the operating handle, and the forceps head is exposed from the sheath tube; a containing groove is arranged on the side of the forceps head facing the ring-shaped cutting edge, the diameter of the containing groove is greater than or equal to the diameter of the ring-shaped cutting edge, and the operating handle is used for controlling the spring tube to move relative to the sheath tube, so that the inner wall of the containing groove abuts against the ring-shaped cutting edge to cut the atrial septum tissue, and the cut atrial septum tissue is located in the space surrounded by the containing groove and the ring-shaped cutting edge. The application solves the problem that the traditional two forceps clamps cannot clamp the thin-walled atrial septum tissue by cutting.

This invention discloses an insulated atrial septum puncture guidewire, comprising a core wire, which includes a middle section, a tip, and a tail. The advantages are as follows: When the guidewire of this invention passes through the atrial septum, compared to traditional mechanical puncture with a needle, the mechanical force required for puncture is much lower. The J-shaped coil at the tip of the guidewire is softer and less sharp, significantly reducing the risk of cardiac perforation and making the procedure safer. Simultaneously, after the guidewire passes through the atrial septum, the sheath and dilator can pass through the septum along with the guidewire. Using the guidewire for atrial septum puncture, compared to the existing technology using mechanical puncture needles, eliminates the need to remove the guidewire from the sheath and insert a needle during the puncture process. The guidewire can simultaneously serve as a guide and puncture point, greatly reducing the number of puncture steps in the atrial septum, lowering the possibility of cardiac damage during atrial septum puncture, and thus reducing the risk of surgical complications.

An apparatus, system, and method for creating a shunt between a right atrium and a left atrium of a patient's heart. An apparatus includes a shielding structure, a tube proximal to the shielding structure, and an actuating mechanism at a proximal end of the tube. The tube is configured to pass through a lumen of a steerable catheter. The actuating mechanism is for deploying the shielding structure through the tube. The shielding structure is configured for passing through an opening in an atrial septum from the right atrium to the left atrium, and for being retracted in a proximal direction to contact the atrial septum for shielding a proximity of the opening from blood flow in the left atrium to facilitate cryoablation of the opening from the right atrium.

The present invention relates to medical devices. More specifically, the present invention describes a vascular device that allows large bore transseptal access with subsequent re-entry into the atrium by pre-placing a closure / tissue access suture prior to performing an atrial septostomy. Generally, the device can include a delivery catheter for puncturing and cutting the atrial septum. An anchor of the delivery catheter can secure the suture in the atrium to the septal wall, e.g., the left atrium. The incision can be formed by an expandable cutting tool that can use mechanical or radiofrequency (RF) energy without disturbing the suture. After the cutting tool forms the incision, a therapeutic device can be advanced through the tissue plane. The incision can be closed with the previously placed suture.

The utility model discloses a double-disc-shaped integrally-formed degradable heart atrial septum foramen ovale plugging device which comprises a first disc part, a second disc part and a plugging part, the first disc part and the second disc part are connected to the two axial ends of the plugging part, and the first disc part, the second disc part and the plugging part are integrally formed pieces. And the first disc part and the second disc part are elastic pieces capable of automatically restoring to original shapes. The plugging device is an integrally-formed degradable part and provides a temporary bridge for self-repairing of the heart, so that self cell tissues can climb and grow, and then the plugging device is degraded and absorbed in the body. Long-term complications and potential safety hazards caused by metal remaining in a human body can be avoided, the plugging device is high in structural integrity, the degradation rate of the plugging device in the human body is uniform, no structural disintegration risk exists, all the defects of an existing plugging device of a woven structure can be overcome, and surgical operation can be simplified.

The present application relates to the field of medical imaging technology, and more particularly to an X-ray image visual prompt system for atrial septum puncture surgery, comprising: a data acquisition and preprocessing module, which acquires preoperative X-ray video to obtain an anatomical structure segmentation mask; a data analysis and generation module, which constructs a puncture point decision model, outputs a puncture region probability map, and generates a candidate puncture point based on the puncture region probability map; a data processing module, which tracks the anatomical structure segmentation mask, determines a spatial average value, optimizes a space-time model through a trajectory-semantic decoupling mechanism, obtains a trajectory consistency loss function, and outputs a prediction result; a data prediction module, which constructs a safe puncture region probability map and generates a dynamic visual prompt map; a data enhancement and decision module, which superimposes and displays the dynamic visual prompt map and the safe puncture region probability map, calculates terminal real-time feedback, and realizes collaborative operation of humans and systems; and through AI assisted analysis and suggestions, the reliability of the puncture surgery is improved.

The application provides a high-axial-support expansion catheter, relates to the technical field of medical devices, and comprises a luer joint; an expansion tube section connected with the luer joint; the expansion tube section comprises a first tube section, a second tube section and a third tube section arranged in sequence in the direction away from the luer joint; the second tube section comprises an inner layer and an outer layer wrapped outside the inner layer; the outer layer is provided with an elastomer, and the hardness of the elastomer is lower than the hardness of the inner layer, the first tube section and the third tube section. When the expansion catheter is used in cooperation with an outer sheath with a complex bending shape, the corresponding bending position of the expansion catheter has high axial strength and sufficient flexibility, so that the expansion catheter can smoothly pass through skin tissue or an atrial septum and the like, the influence of the angle change of the outer sheath is small when the outer sheath is withdrawn, and the sheath can be ensured to be left in a predetermined position.

The application provides an interventional operation robot system for transcutaneous atrial septal defect occlusion, and relates to the technical field of atrial septal defect occlusion interventional operation. The interventional operation robot system is configured to: acquire historical occluder selection data, perform correspondence analysis based on balloon expansion diameter measurement data, and form occluder selection feature data; acquire balloon expansion diameter real-time measurement data, and perform extraction analysis of effective expansion diameter measurement data to form real-time expansion diameter measurement data; perform occluder selection analysis according to the real-time expansion diameter measurement data and the occluder selection feature data, and determine a target occluder; acquire real-time shunt image data, perform shunt effect analysis, and form occlusion effect analysis result data. The interventional operation robot system improves the success rate of the operation by reasonably selecting the occluder through the operation robot, and effectively guarantees and realizes the further operation effect of the interventional operation.

A left atrial appendage (LAA) ligation device is adapted for ligating the LAA via a trans-septal approach, the LAA including an ostium. The LAA ligation device includes a spiral ligation element extending from an end point disposed at a periphery of the spiral ligation element to a center point of the spiral ligation element, the spiral ligation element having a diameter defined by the periphery and a length defined between the periphery and the center point. A delivery device is adapted to releasably secure the spiral ligation element and to enable rotation of the spiral ligation device.

Systems and methods for delivering an implantable occluder device, e.g., an atrial septal defect occluder having a bioresorbable frame, to the atrial septum of a patient are provided. The system may include an outer shaft configured to be removably coupled to a proximal end of the occluder, an inner shaft slidably disposed within the outer shaft and configured to be removably coupled to a distal end of the occluder, and an outer sheath slidably disposed over the outer shaft and having an expandable distal region configured to transition between a collapsed delivery configuration defining an atraumatic tip, and an expanded configuration to facilitate passage of the occluder therethrough. The system may include a handle having slidable and rotatable actuators operatively coupled to the outer shaft, inner shaft, and outer sheath for deploying and releasing the occluder at the atrial septum.

The present disclosure provides a transcatheter occluder device (1) for high venosum atrial septal defects (hv-asds). The device (1) comprises at least one connecting wire (2), a left occluder disk (3), and an asymmetrically designed right occluder disk (4). A first occluder form (A) includes a rear fixation lobe (5), an upper fixation lobe (6), and a lower fixation lobe (7), with the connecting wire (2) connected to the left occluder disk (3) and formed to provide a crown shape. A second occluder form (B) includes a first ring stabilizer (8) as a spiral ring and a second stabilizer (9) at the end of the connecting wire (2) for insertion into the superior vena cava and the inferior vena cava. The connecting wire (2) comprises a mesh wire. The device's (1) asymmetrical design allows secure anchoring to the inferior vena cava rim, addressing the unique challenges of high venosum atrial septal defects.

A method for forming a shunt between the right and left atria of a mammalian heart, the method comprising puncturing an atrial septum between the right and left atria to form the shunt. An ablation device having a balloon is at least partially advanced through the shunt. The balloon is inflated and configured to thermally insulate the atrial septum from the blood within the left and right atria. Ablation energy is delivered to ablate the atrial septum.

The utility model discloses a transcatheter mitral valve repair simulation simulator, which comprises a liquid storage tank, an installation port is arranged on the side wall of the liquid storage tank, the installation port is provided with a cable gland, and the cable gland is used for penetrating through a surgical instrument and realizing dynamic sealing with the surgical instrument; the model assembly is arranged in the liquid storage tank, the model assembly is used for simulating a human heart structure, and the model assembly comprises a heart simulation body and a lower cavity approach tube which are connected with each other; the heart simulation body comprises a simulation main body, an atrial septum simulation part arranged on the simulation main body and a left atrium arranged on the first side of the atrial septum simulation part, the atrial septum simulation part is configured to be punctured by a surgical instrument, the left atrium is provided with a left atrioventricular opening, and the left atrioventricular opening is provided with a mitral valve simulation part. The first end of the lower cavity inlet pipe is communicated with the space of the second side of the atrial septum simulation part, and the second end of the lower cavity inlet pipe corresponds to the cable gland in position.

1. The name of the design product: atrial septum puncture simulation training device for cardiac electrophysiology three-dimensional mapping system. 2. The use of the design product: simulation training for medical personnel. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

A trans-atrial septum surgical system for puncturing an atrial septum within a heart of a patient is disclosed. The transatrial surgical system includes an electrosurgical device configured to be coupled to a radio frequency (RF) energy source and an electroanatomical mapping system coupled to the electrosurgical device. The electrosurgical device includes a delivery component having a delivery component electrode. The electrosurgical device also includes a crossover member located within the lumen and coupled to the RF energy source, the crossover member having crossover member electrodes for delivering RF energy. The mapping system detects positions of the delivery component electrode and the cross-member electrode, determines a distance between the cross-member electrode and the delivery component electrode, and generates an alert if the cross-member electrode extends from the delivery component electrode at a specified projection pitch.

The application relates to an interventional instrument for a heart atrial septum and a manufacturing method. The interventional instrument comprises a first support frame and a second support frame. The manufacturing method is as follows: a cylindrical net is formed by using a wire weaving cylinder; a wire of a first preset point on the first support frame is pulled to expand to form a first passage with a through hole shape; the first preset point is located at a peripheral area of the first support frame; an outer edge of the first support frame is pushed to move to the center at the first preset point, so that an inner side of the first passage is folded and connected to form a notch-shaped first passage at the first preset point; a wire of a second preset point on the second support frame is pulled to expand to form a second passage, wherein the first passage is oppositely arranged with the second passage and is suitable for forming a transseptal passage. The interventional instrument is produced through the above manufacturing method. The interventional instrument can be reliably implanted, and a transseptal passage can be established on the heart atrial septum after implantation.

This invention discloses a dilator for three-dimensional atrial septal puncture, comprising a tube body including a central chamber, a distal end, and a proximal end. The distal end of the tube body has a curved structure, and a cutting end is provided at the distal end of the curved structure. The dilator of this invention allows the position of the needle tip to be accurately displayed in real time in a three-dimensional system, and eliminates the risk of needle tip damage to the superior vena cava and endocardial tissue in other three-dimensional puncture methods.

This utility model discloses a dual-disc, one-piece biodegradable foramen ovale occluder for atrial septum. The occluder includes a first disc, a second disc, and an occluding part. The first and second discs are connected to the two ends of the occluding part. The first, second, and occluding parts are one-piece molded and biodegradable. Both the first and second discs are elastic components that can automatically return to their original shape. The plane containing the edge of the first disc is a first plane, and the plane containing the edge of the second disc is a second plane. The angle between the axis of the occluding part and the first plane is an acute angle, and / or the angle between the axis of the occluding part and the second plane is an acute angle. The occluder is a one-piece biodegradable component, which can avoid long-term complications and safety hazards caused by metal remaining in the body. Furthermore, the first and / or second discs are inclined relative to the occluding part, thereby allowing the first and second discs to adapt to different shapes of heart wall structures and improving the occlusion effect.