88 results about "Atrial septum" patented technology

The invention relates to an atrial septum puncture system, and belongs to the technical field of medical instruments. The atrial septum puncture system comprises a conveying sheath assembly, a dilator assembly and a puncture guide wire. The dilator assembly comprises a dilator, a puncture needle and a control handle. The conveying sheath assembly, the dilator assembly and the puncture guide wire are combined into the atrial septum puncture system, puncture operation is more convenient and safer, and the puncture guide wire and a puncture needle do not need to be frequently exchanged in the puncture operation process; according to the dilator assembly, the control handle comprises the moving part and the limiting part, the moving part is fixedly connected with the near end of the puncture needle, the moving part is used for driving the puncture needle to move in the axial direction of the moving part, and a user can control the puncture needle conveniently; the limiting step is arranged on the outer wall of the moving part, and the axial distance between the near end of the limiting part and the limiting step is 0.5-10 mm, so that the distance of a puncture needle extending out of the dilator can be limited, and the safety of puncture operation can be guaranteed.

Systems and methods for implanting a shunt for regulating blood pressure between a patient's left and right atria are provided. The shunt comprises an anchor having a neck region, first and second end regions, and a conduit affixed with the anchor formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism. The shunt may be advanced through the sheath until the first region protrudes from the sheath and self-expands within the left atrium. The shunt and the sheath may then be retracted until the first region contacts the left side of the atrial septum. The sheath may further be retracted until the counterforce exerted by shunt tension on the atrial septum overcomes the friction of the retained portions of the shunt such that the second region is exposed from the sheath and self-expands within the second atrium.

The application discloses a heart chamber pressure regulating device, which is a cylindrical structure and comprises, in the axial direction of the cylindrical structure, an atrial septum passage and an outflow tract arranged in sequence along the blood flow direction; the side of the atrial septum passage, which is opposite to the outflow tract, is provided with an inflow port; a one-way open valve is arranged in the outflow tract; and the cylindrical structure is provided with a first positioning part and a second positioning part which are respectively arranged on the two sides of the atrial septum. The heart chamber pressure regulating device can form a one-way open valve structure on the atrial septum, is stable in position when cooperating with the atrial septum, can be recycled when the release position is improper, and can be released again.

The application relates to a degradable occluder implantation system, which comprises an occluder body composed of an upper disc, a lower disc and a hollow waist, the upper disc, the lower disc and the waist are formed by weaving wires made of degradable materials, an upper connecting piece comprises an upper connecting part and an upper combining part, a lower connecting piece comprises a lower connecting part and a lower combining part, a conveying device comprises a core connecting piece, a sleeve connecting piece and an outer sheath, the sleeve connecting piece is coaxially movably arranged in the outer sheath, a channel is formed in the middle of the sleeve connecting piece, the core connecting piece is movably arranged in the channel, the upper end of the core connecting piece is detachably connected with the upper connecting part, and the sleeve connecting piece is detachably connected with the lower connecting part. The application pulls the upper connecting piece to move in the inner side of the waist through the core connecting piece, so that the upper connecting piece and the lower connecting piece are close to and combined together, the upper disc and the lower disc are unfolded and attached to the atrial septum, the problem of poor occlusion effect of the degradable occluder is solved, and the risk of thrombus shedding is reduced.

The invention discloses a double-disc-shaped integrally-formed degradable heart atrial septum foramen ovale plugging device which comprises a first disc part, a second disc part and a plugging part, the first disc part and the second disc part are connected to the two axial ends of the plugging part, and the first disc part, the second disc part and the plugging part are integrally-formed pieces. And the first disc part and the second disc part are elastic pieces capable of automatically restoring to original shapes. The plugging device is an integrally-formed degradable part and provides a temporary bridge for self-repairing of the heart, so that self cell tissues can climb and grow, and then the plugging device is degraded and absorbed in the body. Long-term complications and potential safety hazards caused by metal remaining in a human body can be avoided, the plugging device is high in structural integrity, the degradation rate of the plugging device in the human body is uniform, no structural disintegration risk exists, all the defects of an existing plugging device of a woven structure can be overcome, and surgical operation can be simplified.

This invention relates to the field of congenital heart disease treatment technology, and discloses the application of sapropterin in the prevention and treatment of bisphenol fluorene-induced congenital heart disease in fetuses. The congenital heart disease includes cardiac structural defects, heart failure, or cardiomyocyte lesions, specifically selected from ventricular septal defects, atrial septal defects, tetralogy of Fallot, myocardial hypertrophy, decreased cardiac ejection fraction, decreased short-axis contraction rate, cardiomyocyte ferroptosis, myocardial tissue inflammatory infiltration, or myocardial collagen fibrosis. Sapropterin is used as a direct supplement to biological tetrahydropterin (BH4). Through exogenous intervention, it precisely reverses the endogenous BH4 deficiency caused by bisphenol fluorene exposure, restores the expression of GTP cyclase 1 (GCH1) and the dynamic balance of RNA m6A, and upregulates the level of YTH domain family protein 2 (YTHDF2), thereby blocking ferroptosis signal transduction, reducing oxidative stress and inflammatory response, and inhibiting the process of myocardial tissue fibrosis at the molecular level.

The invention relates to the technical field of medical images, in particular to an X-ray image visual prompt system for atrial septum puncture surgery, which comprises a data acquisition and preprocessing module for acquiring preoperative X-ray video to obtain an anatomical structure segmentation mask; the data analysis and generation module is used for constructing a puncture point decision model, outputting a puncture area probability graph and generating candidate puncture points based on the puncture area probability graph; the data processing module is used for tracking the anatomical structure segmentation mask, determining a space average value, optimizing a space-time model through a trajectory-semantic decoupling mechanism, obtaining a trajectory consistency loss function and outputting a prediction result; the data prediction module is used for constructing a safety puncture area probability graph and generating a dynamic visual prompt graph; the data enhancement and decision-making module is used for superposing and displaying the dynamic visual prompt graph and the safety puncture area probability graph, and real-time feedback is carried out by a computing terminal, so that collaborative operation of people and the system is realized; and through AI auxiliary analysis and suggestion, the reliability of the puncture operation is improved.

The invention relates to an atrial septal stoma system, and belongs to the technical field of medical instruments. According to the application, the cutter movably penetrating through the sheathing canal body is arranged, the pushing rod of the capturing device movably penetrates through the cutter, and the traction part of the storage device movably penetrates through the pushing rod, so that the atrial septum tissue can be captured through the capturing device, and the capturing device and the captured atrial septum tissue can be tightened in the storage cavity of the capturing device through the storage device; in addition, the captured atrial septum tissue can be cut through the cutter to form a stoma, and the cut atrial septum tissue is bound through cooperation of the capturing claw and the storage part, so that the cut tissue can be conveniently withdrawn out of the body along with the system, and the cut tissue is prevented from falling off and being left in the atrium.

The present disclosure relates to a method and a device for treating heart failure by normalizing elevated blood pressure in the left and right atria of a heart of a mammal. The present disclosure includes methods for creating and maintaining an opening in the atrial septum. Tools for making an opening and enlarging the opening are also disclosed. Use of the techniques and tools described herein prolongs the patency of an intra-atrial pressure relief opening.

The present application relates to a kind of tissue defect plugging device and tissue defect plugging device.Tissue defect plugging device includes plugging device body, plugging device body is memory material.When plugging device body is in natural relaxed state, all clamping ring is in the same plane, or, adjacent two clamping ring is provided with gap in the direction of straight line perpendicular to its plane, can produce original shape restoring torque, so that the first atrial septum and the second atrial septum produce mutual close tendency, and then make the first atrial septum and the second atrial septum mutually close and close, finally reach the purpose of closing foramen ovale, plugging effect is better, while operation is relatively simple.In addition, because the caliber of clamping ring is different, so as to cancel the flow blocking film, simple structure, also obtain the effect of plugging foramen ovale;In addition, using the above structure design form, the metal material implanted in body is less, can avoid the complication of thrombosis, i.e. not easy to cause adverse reaction.

The application discloses an ostomy device and an ostomy system, and relates to the technical field of medical devices, in particular to an ostomy device and an ostomy system. The ostomy device comprises a puncture assembly, a cutting assembly and a sheath tube assembly. The puncture assembly comprises a mandrel and a puncture part, and the puncture part is arranged at the distal end of the mandrel. The cutting assembly is arranged around the mandrel and at the proximal end of the puncture part. The sheath tube assembly is arranged around the puncture assembly and the cutting assembly, and the distal end of the sheath tube assembly is provided with a receiving tube section. The opening caliber of the distal end of the receiving tube section is adjustable. The distal end of the sheath tube assembly of the ostomy device is provided with the receiving tube section, the opening caliber of the distal end of the receiving tube section is adjustable, and the distal end can form an outwardly expanding horn-shaped opening. When the cutting assembly cuts the atrial septum tissue from the distal end to the proximal end, the receiving tube section can receive the cut tissue, so that the cut tissue cannot escape into the blood circulation and cause thrombosis.

This application relates to a coronary sinus and left atrium shunt system, belonging to the field of medical device technology. The system described in this application, by setting up a puncture component and a shunt component including a cutter, allows for the cutting of a portion of myocardial tissue between the coronary sinus and the left atrium, forming a shunt orifice. This establishes a shunt channel between the coronary sinus and the left atrium, effectively avoiding the embolism risk associated with atrial septal shunts and improving coronary artery blood perfusion, potentially benefiting myocardial recovery.

The invention provides a mitral valve clip operation simulator which comprises a bottom plate, and a first side of the bottom plate is provided with a first storage groove and a second storage groove; the first module is provided with an atrial septum simulation part and a mitral valve simulation part, and the first module is arranged on the bottom plate in the mode that the first module can be switched between an unfolded state and a folded state; the second module is provided with a lower cavity tube used for simulating the inferior vena cava, and the second module is arranged on the bottom plate in a mode of being capable of being switched between an unfolded state and a folded state; when the first module is in an unfolded state, the atrial septum simulation part and the mitral valve simulation part protrude out of the bottom plate, and the positions of the atrial septum simulation part and the mitral valve simulation part form an analogue simulation position; when the second module is in an unfolded state, the lower cavity tube protrudes out of the bottom plate to form a surgical instrument access path; when the first module is in the folded state, the first module is integrally contained in the first containing groove, and when the second module is in the folded state, the second module is integrally contained in the second containing groove.

The invention discloses a double-disc-shaped integrally-formed degradable heart atrial septum foramen ovale plugging device which comprises a first disc part, a second disc part and a plugging part, the first disc part and the second disc part are connected to the two axial ends of the plugging part, and the first disc part, the second disc part and the plugging part are integrally-formed pieces and are degradable pieces; the first disc part and the second disc part are elastic pieces capable of automatically restoring to original shapes, and the first disc part and the second disc part are arranged in parallel. The plugging device is an integrally-formed degradable part and provides a temporary bridge for self-repairing of the heart, so that self cell tissues can climb and grow, and then the plugging device is degraded and absorbed in the body. Long-term complications and potential safety hazards caused by metal remaining in a human body can be avoided, the plugging device is high in structural integrity, the degradation rate of the plugging device in the human body is uniform, no structural disintegration risk exists, all the defects of an existing plugging device of a woven structure can be overcome, and surgical operation can be simplified.

The application provides an atrial septum puncture needle sheath system, and relates to the technical field of medical devices, to solve the problem that the existing technology lacks feedback to the operator when puncturing through the foramen ovale. The atrial septum puncture needle sheath system comprises an expander outer tube, a handle shell, an inner needle assembly, and a pushing mechanism and a pull rod installed in the handle shell. The expander outer tube is connected to the front end of the handle shell. The rear end of the inner needle assembly is arranged in the handle shell, and the front end of the inner needle assembly extends into the expander outer tube. The rear end of the inner needle assembly is movably connected to the front end of the pull rod through a first elastic member. When the front end of the inner needle assembly pierces the puncture site, the first elastic member pushes the inner needle assembly to move relative to the pull rod towards the front end of the pull rod and triggers a feedback mechanism. The atrial septum puncture needle sheath system can trigger the feedback mechanism when the puncture site is pierced, so that the operator can perceive that the inner needle assembly has pierced the puncture site, and further advancement is avoided, thereby improving the safety of operation.

The utility model discloses a double-disc-shaped integrally-formed degradable heart atrial septum foramen ovale plugging device which comprises a first disc part, a second disc part and a plugging part, the first disc part and the second disc part are connected to the two axial ends of the plugging part, and the first disc part, the second disc part and the plugging part are integrally formed pieces. And the first disc part and the second disc part are elastic pieces capable of automatically restoring to original shapes. At least part of at least one of the first disc part and the second disc part is an inverted-cone-shaped ring, and the inverted-cone-shaped ring extends in the direction away from the center of the double-disc-shaped integrally-formed degradable heart atrial septal foramen ovale plugging device from the center to the edge. The plugging device is an integrally-formed degradable part, is used for self cell tissues to climb and grow, and then is degraded and absorbed in vivo. All the defects of an existing plugging device of a woven structure can be overcome, and surgical operation can be simplified. And moreover, the condition that the first disc part or the second disc part hinders the atrial septum foramen ovale of the heart can be reduced, and the working reliability is improved.

The application discloses a myocardial biopsy forceps, and relates to the technical field of medical devices, which comprises an operating handle and a sampling assembly, the operating handle is used for controlling the sampling assembly to extract atrial septum tissue through a sheath tube and a spring tube; the sampling assembly comprises a forceps head and a ring-shaped cutting edge, the ring-shaped cutting edge is fixedly connected with one end of the sheath tube, the other end of the sheath tube is connected with the operating handle, the spring tube is movably arranged in the sheath tube, one end of the spring tube is fixedly connected with the forceps head, and the other end of the spring tube is connected with the operating handle, and the forceps head is exposed from the sheath tube; a containing groove is arranged on the side of the forceps head facing the ring-shaped cutting edge, the diameter of the containing groove is greater than or equal to the diameter of the ring-shaped cutting edge, and the operating handle is used for controlling the spring tube to move relative to the sheath tube, so that the inner wall of the containing groove abuts against the ring-shaped cutting edge to cut the atrial septum tissue, and the cut atrial septum tissue is located in the space surrounded by the containing groove and the ring-shaped cutting edge. The application solves the problem that the traditional two forceps clamps cannot clamp the thin-walled atrial septum tissue by cutting.

Systems, apparatuses, and methods disclosed herein are provided for medical treatment, including transcatheter medical treatments and / or for treatment of dilated hearts (e.g., dilated left ventricle) or functional mitral valve regurgitation within a human heart. The systems, apparatuses, and methods disclosed herein may include applying one or more heart splints to the patient's heart to apply pressure to the heart to reshape the heart. Anchors disclosed herein may be utilized in plugs for treating openings in a septum between two chambers of a heart, e.g., ventricular septal defects (VSD), atrial septal defects (ASD), and patent foramen ovale (PFO). In addition, the anchors disclosed herein may be utilized to reshape an annulus of a patient's heart valve, including a tricuspid valve of a patient's heart. The anchors disclosed herein may also be utilized to reposition a heart valve leaflet to reduce heart valve leaflet prolapse.

This invention discloses an insulated atrial septum puncture guidewire, comprising a core wire, which includes a middle section, a tip, and a tail. The advantages are as follows: When the guidewire of this invention passes through the atrial septum, compared to traditional mechanical puncture with a needle, the mechanical force required for puncture is much lower. The J-shaped coil at the tip of the guidewire is softer and less sharp, significantly reducing the risk of cardiac perforation and making the procedure safer. Simultaneously, after the guidewire passes through the atrial septum, the sheath and dilator can pass through the septum along with the guidewire. Using the guidewire for atrial septum puncture, compared to the existing technology using mechanical puncture needles, eliminates the need to remove the guidewire from the sheath and insert a needle during the puncture process. The guidewire can simultaneously serve as a guide and puncture point, greatly reducing the number of puncture steps in the atrial septum, lowering the possibility of cardiac damage during atrial septum puncture, and thus reducing the risk of surgical complications.

An apparatus, system, and method for creating a shunt between a right atrium and a left atrium of a patient's heart. An apparatus includes a shielding structure, a tube proximal to the shielding structure, and an actuating mechanism at a proximal end of the tube. The tube is configured to pass through a lumen of a steerable catheter. The actuating mechanism is for deploying the shielding structure through the tube. The shielding structure is configured for passing through an opening in an atrial septum from the right atrium to the left atrium, and for being retracted in a proximal direction to contact the atrial septum for shielding a proximity of the opening from blood flow in the left atrium to facilitate cryoablation of the opening from the right atrium.

The present application provides a heart valve positioning device, comprising: a supravalvular structure, a subravalvular structure, a connector, and a locking structure, wherein the supravalvular structure, the subravalvular structure, and the connector are all tubular structures, and the supravalvular structure and the subravalvular structure each form a curved structure in the released state; the subravalvular structure has a first end and a second end, the first end and the second end are separated from each other in the delivery state, and can be connected to each other through the locking structure in the released state, so that the subravalvular structure forms a closed ring, and the subravalvular structure retracts at least a portion of the native valve leaflets inside the closed ring, and the supravalvular structure is anchored to the inside of the native valve ring. The heart valve positioning device of the present application and the artificial valve are delivered through the atrial septum from the same pathway, which is simple to operate and can avoid causing damage to the aortic valve.

The present invention relates to medical devices. More specifically, the present invention describes a vascular device that allows large bore transseptal access with subsequent re-entry into the atrium by pre-placing a closure / tissue access suture prior to performing an atrial septostomy. Generally, the device can include a delivery catheter for puncturing and cutting the atrial septum. An anchor of the delivery catheter can secure the suture in the atrium to the septal wall, e.g., the left atrium. The incision can be formed by an expandable cutting tool that can use mechanical or radiofrequency (RF) energy without disturbing the suture. After the cutting tool forms the incision, a therapeutic device can be advanced through the tissue plane. The incision can be closed with the previously placed suture.

The invention discloses a pair of myocardial biopsy forceps, and relates to the technical field of medical instruments, the scheme is that the pair of myocardial biopsy forceps comprises an operating handle and a sampling assembly, the operating handle is used for controlling the sampling assembly to extract atrial septum tissue through a sheathing canal and a spring tube; the sampling assembly comprises a forceps head and an annular blade, the annular blade is fixedly connected with one end of the sheath tube, the other end of the sheath tube is connected with the operating handle, the spring tube is movably arranged in the sheath tube, one end of the spring tube is fixedly connected with the forceps head, the other end of the spring tube is connected with the operating handle, and the forceps head is exposed out of the sheath tube; a containing groove is formed in the side, facing the annular blade, of the forceps head, the diameter of the containing groove is larger than or equal to that of the annular blade, and the operating handle is used for controlling the spring tube to move relative to the sheathing canal so that the inner wall of the containing groove can abut against the annular blade to cut the atrial septum tissue. The cut atrial septum tissue is located in the space defined by the containing groove and the annular blade. The problem that two traditional forceps holders cannot clamp thin-wall and slippery atrial septum tissue is solved in a cutting mode.

The present invention relates to a delivery system for a cardiac shunt, and the operating steps are as follows: a) a delivery sheath is combined with a puncture sheath and a puncture needle to enter the atrium and puncture the atrial septum. After completion, the puncture sheath and puncture needle are withdrawn, leaving the delivery sheath in the body; b) a release shaft is passed through a straightening sheath, a threaded hole of the cardiac shunt is screwed to a screw at one end of the release shaft, the release shaft is slid to retract the cardiac shunt into the straightening sheath, and a locking knob is turned to control a tension sleeve to clamp the release shaft; c) the straightening sheath (b) is clamped and connected to the delivery sheath, the locking knob is turned to control the tension sleeve to just loosen the release shaft, and the release shaft is slid to allow the cardiac shunt to enter the delivery sheath; d) the release shaft is then continued to slide to allow the cardiac shunt to extend from the other end of the delivery sheath and restore its umbrella-shaped structure, and then clamped to the target atrial septum; e) a handle is turned to disengage the release shaft from the cardiac shunt, and the delivery system is then withdrawn from the body. The present invention has a simple structure, is easy to operate, and greatly improves safety.

The utility model discloses a double-disc-shaped integrally-formed degradable heart atrial septum foramen ovale plugging device which comprises a first disc part, a second disc part and a plugging part, the first disc part and the second disc part are connected to the two axial ends of the plugging part, and the first disc part, the second disc part and the plugging part are integrally formed pieces. And the first disc part and the second disc part are elastic pieces capable of automatically restoring to original shapes. The plugging device is an integrally-formed degradable part and provides a temporary bridge for self-repairing of the heart, so that self cell tissues can climb and grow, and then the plugging device is degraded and absorbed in the body. Long-term complications and potential safety hazards caused by metal remaining in a human body can be avoided, the plugging device is high in structural integrity, the degradation rate of the plugging device in the human body is uniform, no structural disintegration risk exists, all the defects of an existing plugging device of a woven structure can be overcome, and surgical operation can be simplified.

The present application discloses an atrial septal puncture kit, comprising a sheath, an expansion tube and a puncture tube, wherein the expansion tube has a distal channel and a proximal channel, and the connection position of the distal channel and the proximal channel forms a step surface; a limiting sleeve is fixedly installed in the proximal channel, a threading channel is provided in the side wall of the expansion tube, a pressing protrusion is provided at the step surface, a metal wire is provided in the threading channel, and an elastic block is fixed to the metal wire; a mounting block is fixed to the puncture tube, a mounting hole is provided on the circumferential surface of the mounting block, a first pressure sensor is installed in the mounting hole, and the first pressure sensor is connected to a movable block via a spring; the end face of the mounting block close to the pressing protrusion has a mounting groove, a second pressure sensor is installed in the mounting groove; the proximal end of the metal wire has a scale line. The atrial septal puncture kit of the present application can achieve better control over the pushing of the puncture tube, thereby avoiding damage to the human body.

The present application relates to the field of medical imaging technology, and more particularly to an X-ray image visual prompt system for atrial septum puncture surgery, comprising: a data acquisition and preprocessing module, which acquires preoperative X-ray video to obtain an anatomical structure segmentation mask; a data analysis and generation module, which constructs a puncture point decision model, outputs a puncture region probability map, and generates a candidate puncture point based on the puncture region probability map; a data processing module, which tracks the anatomical structure segmentation mask, determines a spatial average value, optimizes a space-time model through a trajectory-semantic decoupling mechanism, obtains a trajectory consistency loss function, and outputs a prediction result; a data prediction module, which constructs a safe puncture region probability map and generates a dynamic visual prompt map; a data enhancement and decision module, which superimposes and displays the dynamic visual prompt map and the safe puncture region probability map, calculates terminal real-time feedback, and realizes collaborative operation of humans and systems; and through AI assisted analysis and suggestions, the reliability of the puncture surgery is improved.

The application provides a high-axial-support expansion catheter, relates to the technical field of medical devices, and comprises a luer joint; an expansion tube section connected with the luer joint; the expansion tube section comprises a first tube section, a second tube section and a third tube section arranged in sequence in the direction away from the luer joint; the second tube section comprises an inner layer and an outer layer wrapped outside the inner layer; the outer layer is provided with an elastomer, and the hardness of the elastomer is lower than the hardness of the inner layer, the first tube section and the third tube section. When the expansion catheter is used in cooperation with an outer sheath with a complex bending shape, the corresponding bending position of the expansion catheter has high axial strength and sufficient flexibility, so that the expansion catheter can smoothly pass through skin tissue or an atrial septum and the like, the influence of the angle change of the outer sheath is small when the outer sheath is withdrawn, and the sheath can be ensured to be left in a predetermined position.