716 results about "Stomach" patented technology

The invention belongs to the technical field of bioengineering, and particularly relates to leuconostoc mesenteroides subsp. Mesenteroides FTCM002 and application thereof in preparation of dendrobium officinale leavening with the effects of reducing blood sugar, nourishing the stomach and resisting inflammation. Dendrobium officinale is subjected to enzymolysis and inoculated with the strain for fermentation, and the obtained fermented dendrobium officinale has the effect of inhibiting alpha-glucosidase; the gastric mucosal injury can be relieved, the expression of VEGF, IL-6, IL-8 and TNF-alpha in the gastric mucosal injury is reduced, and the effect of nourishing the stomach is achieved; the cell phagocytic rate can be increased, the NO concentration and the content of immune factors IL-6 and TNF-alpha can be increased, and the effect of enhancing the immunity is achieved; the expression quantity of IL-6, IL-1beta and TNF-alpha in inflammatory cells can be reduced, and the anti-inflammatory effect is achieved.

The invention discloses a gastric retention capsule robot and a gastric retention capsule device, and relates to the technical field of medical instruments, the gastric retention capsule robot comprises a capsule shell, a robot body, an unfolding arm, a driving mechanism and a restoring mechanism; the robot body is arranged in the capsule shell, and a carrying module used for carrying the functional module is arranged on the robot body; the unfolding arm is movably arranged on the robot body; the driving mechanism is arranged on the robot body, and after the capsule shell is dissolved, the driving mechanism can drive the unfolding arm to unfold towards the outside of the robot body so as to limit discharging of the robot body; the restoring mechanism is arranged on the robot body and can fold the unfolding arm to be attached to the robot body so that the robot body can be discharged. The device can be detained in the stomach and can be discharged from the gastral cavity through active folding, the timeliness is good, the risks of gastrointestinal tract blockage, mechanical injury and the like existing in a passive discharging mode are avoided, and the personal safety of a patient is guaranteed.

The invention discloses a strain of lactobacillus fermentum LF-HF25 obtained by screening sour cucumber, which is preserved in the China Center for Type Culture Collection, the preservation number is CCTCC No.M20241566, the classification name is the lactobacillus fermentum LF-HF25, the preservation date is July 15, 2024, and the preservation address is Wuhan University, China. The lactobacillus fermentum LF-HF25 has the advantages that the preservation number is CCTCC No.M20241566, the classification name is the lactobacillus fermentum LF-HF25, the preservation date is July 15, 2024, and the preservation address is Wuhan University, China. The lactobacillus mucilaginosus LF-HF25 or the metabiotic microbial inoculum prepared from the lactobacillus mucilaginosus LF-HF25 has the functions of dispelling the effects of alcohol, protecting the liver, promoting digestion and nourishing the stomach, also has the effect of improving sleep, and has a wide application prospect.

The invention relates to the technical field of functional food and biological medicine, in particular to a modified pseudo-ginseng exosome and an intestinal conditioning gel composition and application thereof. According to the gel beverage, an exosome derived from panax notoginseng callus cultured in a laboratory is used as a core active component, is modified through phosphatidylserine-aminated pectin-genipin and is embedded into a hydrogel matrix composed of carboxymethyl chitosan and sodium alginate, so that the exosome is protected from being degraded in the stomach, and the activity of the exosome in the stomach is improved. The exosome can be effectively released under the intestinal pH and flora environment, so that the targeted delivery of the intestinal tract is realized, and the preparation method is suitable for improving the intestinal inflammation and maintaining the intestinal health. The invention can effectively solve the technical problems of uncontrollable raw material quality and safety, low oral delivery stability and active ingredient availability and poor medication compliance of the existing plant exosome.

The invention relates to a traditional Chinese medicine composition for treating allergic dermatitis. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicines in parts by weight: 5-35 parts of fried coix seeds, 5-35 parts of concha margaritifera, 1-30 parts of honeysuckle stems, 1-30 parts of smoked plums, 1-30 parts of fructus liquidambaris, 1-25 parts of fructus forsythiae, 1-25 parts of radix paeoniae rubra, 1-25 parts of raw sanguisorba officinalis, 1-25 parts of radix glehniae, 1-25 parts of radix ophiopogonis and 1-25 parts of raw radix polygonati officinalis. 1-25 parts by weight of talc and 1-25 parts by weight of lophatherum gracile. The traditional Chinese medicine composition has the effects of clearing heat, cooling blood without bitter cold, dispelling wind, eliminating dampness without hurting stomach, detoxifying, relieving itching and nourishing yin, is safe in clinical use, and has no adverse effect on liver and kidney.

The invention provides microcapsule seasoning powder containing active plant components for cats and a preparation method of the microcapsule seasoning powder, the microcapsule seasoning powder comprises a double-layer embedding system, and the microcapsule seasoning powder comprises the following raw material components in percentage by weight: 10-14 wt% of a composite core material, 32-36 wt% of a multifunctional food calling base material, 35-39 wt% of the double-layer embedding system and 14-16 wt% of functional auxiliary materials; the composite core material is prepared by compounding a mint extract, a green tea extract, a chicory extract, a mulberry leaf extract and a hawthorn extract according to the mass ratio of (1.8-4.5): (1.2-3): (0.8-1.5): (0.5-1.2): (1-2). The cat food has a dual-stage targeting effect of low release in the stomach and high release in the intestinal tract, has high palatability, has the effects of promoting the health of the intestinal tract, improving metabolism and resisting aging synergistically, is long-acting and stable, and can be suitable for various types of functional foods for cats.

The invention belongs to the technical field of traditional Chinese medicine tablet manufacturing, and particularly relates to an online quality prediction method for stomach invigorating and digestion promoting tablets based on multi-modal fusion. Comprising the following steps: synchronously acquiring hyperspectral imaging data and near infrared spectrum data of a stomach invigorating and digestion promoting tablet sample; processing the near infrared spectrum data through a one-dimensional convolutional neural network to extract a first spectrum feature; parallel extraction of spatial features and spectral features is carried out on the hyperspectral imaging data through a double-branch feature extraction network; performing intra-modal fusion on the extracted spatial features and the second spectral features through a cross attention mechanism to obtain hyperspectral fusion features, and performing cross-modal fusion on the hyperspectral fusion features and the first spectrum through cross-modal multi-head attention to generate fusion features; and outputting a quality index prediction value of the stomach invigorating and digestion promoting tablets through a regression prediction module based on the fusion features.

The invention relates to the technical field of traditional Chinese medicines, in particular to application of a traditional Chinese medicine composition in preparation of a medicine for preventing and treating motor symptoms of Parkinson's disease. The traditional Chinese medicine composition is prepared from the following raw material medicines: 15-20 parts of rehmannia, 10-15 parts of eucommia ulmoides, 6-12 parts of gastrodia elata, 12-18 parts of concha haliotidis, 10-15 parts of parasitic loranthus, 12-18 parts of astragalus membranaceus, 6-12 parts of angelica sinensis, 5-8 parts of cassia twig and 10-15 parts of radix paeoniae alba. The composition is scientific and reasonable in component compatibility, has the effects of tonifying the kidney, calming the liver, benefiting qi, nourishing blood, regulating and tonifying the spleen and the stomach, relieving dizziness, activating blood, clearing damp and dredging collaterals, is safe to take and good in curative effect, can be effectively used for preventing and treating motor symptoms of the Parkinson's disease, and has a more remarkable treatment effect compared with other prescriptions.

The invention relates to a cattle stomach momentum anomaly identification method based on machine learning, and belongs to the field of animal husbandry digitization. The method comprises the following steps of S1, data acquisition, S2, data preprocessing, S3, feature construction, S4, stomach momentum state label construction, S5, sample imbalance processing, S6, model construction and training, and S7, model evaluation and parameter adjustment. The method not only makes obvious breakthrough in theoretical modeling precision and practical deployment efficiency, but also realizes substantive crossing of experience-driven cattle stomach momentum management to data-driven cattle stomach momentum management through experimental verification, and provides powerful technical support for health early warning and asset management in an intelligent animal husbandry scene.

The invention discloses a pediatric spleen and stomach dynamic monitoring method and system based on an AI chip, and belongs to the field of medical health information technology and artificial intelligence chip application. The pediatric spleen and stomach dynamic monitoring method comprises the steps that a multi-mode original data set is collected, signal preprocessing is conducted, and a feature data set is obtained; key indexes of spleen and stomach syndromes are identified from the feature data set based on the viscera differentiation theory, and a dialectical result is obtained; inputting the feature data set into a dialectical verification model to generate a spleen and stomach health assessment value; when the spleen and stomach health assessment value is smaller than an assessment threshold value, a first-level health early warning signal is generated; and when the duration of the first-stage health early warning signal is greater than a duration threshold, generating a second-stage combined early warning signal according to pre-acquired user behavior log data. A multi-modal data fusion technology, a dynamic noise reduction algorithm and a grading early warning mechanism are adopted, and doctors can be assisted in achieving precise evaluation of the spleen and stomach states of children and personalized traditional Chinese medicine intervention.

The invention belongs to the technical field of medical service information sharing, and discloses a gastrointestinal medical service information sharing system based on artificial intelligence. The system comprises a collaborative learning modeling module, a patient digital portrait generation module, a personalized digital twinborn body construction module, a treatment effect prediction module, a personalized strategy generation module, a real-time interaction feedback module and a self-adaptive optimization iteration module, and is characterized in that a feature extraction model is trained based on an original data set; generating a feature vector according to the original data set, constructing a patient digital portrait database based on the feature vector, constructing a digital twinborn body of a specified patient, obtaining a prediction quantification report, obtaining a user health management report, obtaining a user interaction data set, and obtaining a new agent model. The method has the remarkable advantages of being high in basic data supporting performance, accurate in dynamic prediction, specific in health suggestion and high in self-adaptive optimization capacity.

The utility model discloses a gastrostomy tube, and belongs to the field of medical equipment. Comprising a tube body, a connecting piece and a connecting piece, wherein one end of the tube body is provided with an air bag; one end of the stomach catheter and one end of the gas-guide tube extend out of the end, away from the gas bag, of the tube body, and the other end of the stomach catheter is flush with one end of the tube body. A control button used for controlling the air bag to stretch out of the tube body is arranged at the end, away from the air bag, of the air guide tube. The gastrostomy tube has the advantages that the gastrostomy tube can be conveniently placed in the stomach and is not prone to sliding out.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating gastroesophageal reflux cough and a preparation method thereof. The traditional Chinese medicine composition disclosed by the invention is constructed by carefully selecting a medicine formula under the guidance of a traditional Chinese medicine theory and clinical experience and through a compatibility theory of monarch, minister, assistant and guide of traditional Chinese medicines. In the traditional Chinese medicine composition, the inula flower has the effects of promoting blood circulation, removing stasis and turbidity, clearing the airway and removing phlegm and fluid retention, and the mangnolia officinalis has the effects of promoting qi circulation, removing food retention, calming adverse-rising energy and relieving asthma, and both serve as monarch drugs; the dried orange peel has the effects of regulating qi and removing stagnation, the poria cocos has the effects of tonifying spleen, eliminating dampness and phlegm and breaking up the source of phlegm, and the bulbus fritillariae cirrhosae has the effects of clearing heat and moistening lung and resolving phlegm and relieving asthma; the rhizoma atractylodis macrocephalae has the effects of invigorating the spleen, replenishing qi, eliminating dampness and inducing diuresis, and the endothelium corneum gigeriae galli has the effects of promoting digestion and invigorating the stomach and is an assistant and guide drug. The whole prescription is ordered in monarch and minister, focuses on pathogenesis, is rigorous in prescription, has the effects of relieving cough and asthma, clearing heat and moistening lung, and strengthening spleen and stomach, and treats both symptoms and root causes of cough.

The invention relates to genetic engineering combined lactobacillus salivarius and application of the genetic engineering combined lactobacillus salivarius. The strain is classified and named as combined lactobacillus salivarius CTMT2, and the preservation number of the strain is CCTCC (China Center for Type Culture Collection) M 2025547. After an NIAAA model is injected into the stomach of an alcoholic liver mouse, the acetaldehyde level of the liver of the mouse is obviously reduced, and the alcoholic fatty liver symptom of the mouse is obviously relieved; after long-term intragastric administration of a high-glucose and high-fat modeling mouse, the acetaldehyde level in excrement of the mouse can be obviously reduced, the progress of liver fibrosis is improved, and good application prospects are achieved.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition with an effect of preventing and treating alcoholic liver injury as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines: radix puerariae, turmeric, ginseng, hovenia dulcis thunb, white hyacinth bean, raw oyster shell, poria cocos, raw hawthorn, biond magnolia flower, juncus effuses and albizia flower. The traditional Chinese medicine composition has the effects of soothing liver and harmonizing stomach, dispelling alcohol effect and enlivening spleen, and reinforcing qi and nourishing blood. Experimental results show that the traditional Chinese medicine composition has a good treatment effect on acute alcoholic liver injury and chronic alcoholic fatty liver, and can effectively improve the symptoms of chest rib swelling pain, reduced appetite, anorexia, abdominal distension, hiccup, belching, borborygmus and qi and loose stool caused by liver-stomach disharmony and spleen deficiency and dampness of alcoholic liver injury patients; therefore, the method has good development and utilization prospects.

The invention relates to the technical field of traditional Chinese medicine, and provides a traditional Chinese medicine composition capable of regulating spleen and stomach and tonifying qi and producing blood and a preparation method thereof.The traditional Chinese medicine composition is prepared from, by weight, 15-25 parts of rhizoma polygonati, 8-15 parts of bee pollen, 12-20 parts of poria cocos, 10-18 parts of semen euryales, 6-12 parts of dandelion, 8-15 parts of semen raphani, 10-20 parts of purple perilla, 12-20 parts of malt and 10-18 parts of hawthorn. According to the technical scheme, the problem that the traditional Chinese medicine composition in the prior art is insufficient in spleen and stomach regulating, qi tonifying and blood generating effects is solved.

A leak detecting apparatus (1) for detecting a leak and determining the size of the leak in a suture repaired site (5) of a hollow organ (3), for example, a stomach, in a cavity (7), for example, the peritoneal cavity of a subject comprises a first insufflator (12) for insufflating the hollow organ (3) with a first gas, and a second insufflator (14) for insufflating the cavity (7) with a second gas. A gas detector (18) is provided for detecting the concentration of the first gas in gases exhausted from the cavity (7) through a communicating conduit (35). A flow meter (25) monitors the flow rate of the first gas to the hollow organ (3). First and second pressure sensors (15) and (16) monitor the static pressure of the first and second gases in the hollow organ (3) and the cavity (7), respectively. The apparatus (1) is operable in a first mode and a second mode. In both the first and second modes of operation a microprocessor (50) controls the second insufflator (14) for maintaining the pressure in the cavity (7) at a relatively low predefined pressure, and the first insufflator (12) for maintaining a constant predefined pressure differential between the pressures in the hollow organ (3) and the cavity (7) of approximately 7 mmHg. In the first mode the microprocessor (50) determines the size of the leak as a function of the pressure differential and the concentration of the first gas in the exhaust gases. In the second mode of operation the microprocessor (50) determines the size of the leak as a function of the pressure differential and the flow rate of the first gas to the hollow organ (3) with the hollow organ (3) sealed apart from the sutured site (5).

The invention discloses an anorectal surgery cleaning drug delivery device which comprises a liquid storage bag, a drug delivery mechanism, a first driving mechanism and an anti-backflow mechanism, the drug delivery mechanism is provided with a liquid outlet, the drug delivery mechanism comprises a drug delivery head and a drug delivery rod, the drug delivery rod is provided with a middle flow channel, the drug delivery head drives the drug delivery rod to rotate, and the first driving mechanism is provided with a moving rod. The anti-backflow mechanism comprises a telescopic rod and rotating rods rotationally arranged on the telescopic rod, a flexible connecting part is arranged between every two adjacent rotating rods, the rotating rods can be driven to stretch out or retract, and the telescopic rod can be driven to stretch out of the dosing head or retract into the dosing head. A first air bag part is arranged between the rotating rod and the movable end of the telescopic rod, and the rotating rod is expanded or contracted through expansion or contraction of the first air bag part. The anti-backflow mechanism can prevent the liquid medicine from moving towards the stomach, the turbulent flow of the liquid medicine is reduced, the swelling pain feeling of a patient is relieved, and the treatment comfort is improved.

1. The name of the design product: medicine box (Hedgehog stomach capsule). 2. The use of the design product: used for the outer packaging of medicines. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective drawing.

The invention relates to the technical field of drug delivery, in particular to silk-based oral hydrogel as well as a preparation method and application thereof. The invention discloses and provides a preparation method of a hydrogel material which is based on fibroin, can be subjected to rapid gelation reaction and can be swallowed, subjected to gastric retention and enteric-coated. The material can be used for entrapment and multi-drug joint co-loading of water-phase soluble drugs or insoluble drugs. The hydrogel has the characteristics of excellent mechanical properties and shear thinning, is easy to swallow, and can effectively penetrate through the esophagus to enter the gastrointestinal tract. The hydrogel can be retained in the stomach for more than 24 hours, and responds to pancreatin in the enteric cavity to be degraded and release the entrapped medicine. In conclusion, the fibroin-based hydrogel capable of being swallowed, retained in the stomach and enteric, which can be subjected to rapid gelation reaction, has relatively high application value in the fields of oral drug carriers, oral health-care products, wound gel dressings, antibacterial materials and the like.

The application discloses a kind of solid teeth pain-relieving and inflammation-clearing traditional Chinese medicine composition, it is related to traditional Chinese medicine product technical field.The composition is composed of gypsum, raw rehmannia, coptis, talc, ocher, radix cyathulae and salvia miltiorrhiza seven raw medicinal materials, wherein gypsum, raw rehmannia are monarch drug, clear and purge stomach fire, cool blood and nourish yin;Coptis, talc are ministerial drug, clear heat and dry dampness, lead heat down;Ocher, radix cyathulae are auxiliary drug, heavy town counteract, lead fire down;Salvia miltiorrhiza is servant drug, promote blood circulation and remove blood stasis, promote tissue repair.Modern pharmacological research shows that each drug of the present party has the effects of anti-inflammatory, analgesic, antibacterial, improving microcirculation and protecting periodontal tissue etc.Clinical observation shows that the pain of most patients caused by stomach fire attacking upward, gum redness and swelling, burning pain, bleeding is significantly reduced after taking 1-2 doses, redness and swelling gradually subside.Compared with existing Chinese patent medicines, the present application is simple in prescription, low in cost, has the dual effects of rapid pain relief and long-term tooth fixation, and is especially suitable for patients with recurrent toothache and early periodontitis.

The invention relates to the technical field of medical nursing, and discloses an intestine and stomach nursing decompression device applied to nursing in the digestive department, which comprises a pressing device and a reset spring arranged in the pressing device, the exhaust assembly is fixedly arranged on the inner wall of the top of the pressing device, the release assembly is arranged on the outer wall of the bottom of the pressing device, the flow guide assembly is arranged on the inner wall of the release assembly, the connecting assembly is arranged on the inner wall of the flow guide assembly, the allowance shrinking assembly is arranged at the other end of the connecting assembly, and the storage barrel is arranged on the allowance shrinking assembly. A patient can adjust the negative pressure by himself or herself, the patient can adjust the pressing strength and frequency of the pressing device in real time according to the gastrointestinal feeling of himself or herself, the negative pressure strength is fed back and adjusted, meanwhile, the telescopic component buffers airflow impact, the air outlet notch divides airflow, the negative pressure stability is ensured, mucous membrane injury or insufficient drainage caused by fixed negative pressure is avoided, and therefore the use comfort is improved.

The purpose of the present invention is to provide a novel method for culturing tissue-derived cells. The method uses a cell culture method including a step for co-culturing cells derived from the skin and at least one type of cell selected from among cells derived from the intestine, cells derived from the heart, cells derived from the brain, cells derived from the stomach, cells derived from the embryonic membrane, cells derived from the kidney, and cells derived from the lung. And culturing the skin-derived cells.

The utility model discloses a spleen and stomach physiotherapy massage device, relates to the technical field of physiotherapy, and aims to solve the technical problem that a massage device in the prior art cannot be adjusted according to the stature of a user. The massage device comprises an outer cylinder and an inner cylinder arranged in the outer cylinder, a plurality of massage protrusions are arranged on the inner cylinder, first holes matched with the massage protrusions are formed in the outer cylinder, the massage protrusions are arranged in the first holes, and an adjusting device for driving the massage protrusions to stretch out and draw back is arranged in the inner cylinder. By adopting the inner cylinder, the outer cylinder, the adjusting device and the like, different users can adjust the lengths of the massage bulges extending out of the outer cylinder according to the stature conditions of the users, so that the acupuncture points can be better massaged when the users use the device, the massage effect is improved, and meanwhile, the practicability of the device is also improved.

The application belongs to the technical field of biomedical application of nanomaterials, and discloses a magnetic graphene nanocapsule as well as a preparation method and application thereof. The application provides a magnetic graphene nanocapsule, wherein the magnetic graphene nanocapsule is of a core-shell structure, the core is a magnetic metal, and the shell layer is a magnetic graphene nanocapsule, compared with traditional magnetic metal oxides, the heat production capacity and acid resistance are significantly enhanced, and stable hyperthermia conditions can be provided in the stomach. The application further provides a preparation method of the magnetic graphene nanocapsule, wherein inexpensive and readily available raw materials such as metal chloride and nitrate are used, the synthesis conditions are simple, and the method is suitable for mass production. The obtained magnetic graphene nanocapsule can enter a specified site through oral administration, such a drug administration mode can avoid the problems of liver accumulation and side effects of nanoparticles after entering the blood, and potential toxicity of nanoparticles after entering the systemic circulation is avoided.

The application discloses tea polyphenol-beta-cyclodextrin inclusion gel microspheres based on electrostatic spraying, and a preparation method and application thereof, and relates to the fields of pharmaceutical preparations and functional foods. The gel microspheres prepared by the method have small particle sizes and good pH response characteristics, can keep an aggregated state and a relatively stable gel structure in a simulated stomach acid environment, gradually disintegrate in a simulated intestinal environment, and realize slow release of tea polyphenols, so that the release behavior of tea polyphenols in a gastrointestinal environment is improved. In addition, the electrostatic spraying technology is adopted to prepare the small-particle-size gel microspheres, without the need of using microfluidic equipment which is complex in structure and high in cost, so that the application has the advantages of low equipment requirement, simple operation and low preparation cost, and has a good application prospect in the fields of functional foods and delivery of pharmaceutical active substances.

1. The name of the design product: far infrared abdominal belt. 2. The use of the design product: abdominal belt for lower abdomen, stomach cold, waist. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

This invention relates to the field of emulsion technology, specifically disclosing a method for preparing a casein micelle-phenol-whey protein ternary complex, comprising: S1, screening bovine milk with κ-casein genotype AA, and using it as raw material to prepare a casein micelle solution; S2, adding a phenolic compound to the casein micelle solution to form a casein micelle-phenol binary complex mixed solution; S3, dialyzing the mixed solution obtained in step S2; S4, adding whey protein; by combining a phenolic compound (such as EGCG) with casein micelles and whey protein to form a ternary complex, the degree to which proteins form dense clots in the stomach can be reduced, making the clot structure looser, thereby accelerating the digestion rate and reducing stomach discomfort.

The application belongs to the technical field of enzyme preparation processing, and specifically provides a preparation method of a gastric-stable enzyme preparation, which comprises the following steps: (1) placing enzyme liquid in a stirrer, adding stabilizers and carriers into the enzyme liquid, uniformly stirring, then adding emulsifiers and emulsion stabilizers, uniformly stirring again, obtaining enzyme mixture, and heating and keeping warm; (2) heating hot-melt type packaging materials to completely melt into liquid state, and keeping the packaging materials in liquid state; (3) starting the stirrer, slowly pouring the liquid hot-melt type packaging materials into the stirrer while stirring, and obtaining a material liquid; (4) spray drying the material liquid, and obtaining the gastric-stable enzyme preparation. The preparation method provided by the application effectively avoids the destruction of the prepared enzyme preparation by pepsin after the enzyme preparation enters the stomach of an animal, improves the enzyme activity retention rate of the enzyme preparation product after passing through the stomach, and further improves the stability of the enzyme preparation in the storage process, especially the storage stability in a humid environment.