418 results about "Lactobacillus casei" patented technology

The invention relates to the technical field of microorganisms, in particular to application of lactobacillus rhamnosus KF7 in improving intestinal barrier injury and regulating intestinal flora and functional food containing the lactobacillus rhamnosus KF7. The invention provides application of lactobacillus rhamnosus KF7 in preparation of a product for improving intestinal barrier injury and / or regulating intestinal flora. The preservation number of the lactobacillus rhamnosus KF7 is CGMCC (China General Microbiological Culture Collection Center) NO.6430. The invention further provides application of the lactobacillus rhamnosus KF7 in preparation of a product for improving intestinal barrier injury and / or regulating intestinal flora. The invention discloses the novel application of the caseus rhamnosus KF7 in the aspects of improving the normal intestinal epithelial barrier function, protecting the normal intestinal epithelial barrier from lipopolysaccharide induced barrier injury, recovering animal intestinal barrier injury caused by rhythm disorder, regulating intestinal flora disorder and improving growth, development and metabolic states for the first time. The method can be used for producing functional food products such as fermented milk, lactic acid bacteria beverages, probiotic powder, viable bacteria water, milk powder and cheese.

The invention belongs to the technical field of microorganisms, and particularly relates to a postbiotic preparation for pets as well as a preparation method and application of the postbiotic preparation. The metabolite preparation provided by the invention comprises a lactobacillus plantarum Ps-8 inactivated thallus and a metabolite thereof, a lactobacillus casei C-9 inactivated thallus and a metabolite thereof, a bifidobacterium animalis subsp. Lactis BB-16 inactivated thallus and a metabolite thereof, and a lactobacillus acidophilus LA-14 inactivated thallus and a metabolite thereof. The pet food can be applied to various food types of different varieties of cat and dog pets, and has the effects of improving the intestinal barrier function of the pets, enhancing the immunity, reducing the incidence rate of diarrhea, reducing the food change stress, promoting the digestion of nutrient substances, optimizing the state of spirit and fur, reducing the odor of excrement, fading the odor of the oral cavity, improving the health level of the oral cavity and teeth and the like.

The invention belongs to the technical field of microorganisms, and particularly relates to lactobacillus paracasei ZY and application thereof, and the preservation number of the lactobacillus paracasei ZY is CGMCC (China General Microbiological Culture Collection Center) No.30303. The invention provides the lactobacillus paracasei ZY capable of regulating the iron balance of intestinal tracts, and the lactobacillus paracasei ZY also can promote the growth of saccharomyces cerevisiae. The animal feed prepared from the lactobacillus paracasei ZY can regulate the iron absorption of intestinal tracts according to the iron content in blood, promote the intestinal tracts to autonomously regulate the iron balance, and effectively solve the problem of iron balance imbalance in large-scale production; a fermented product prepared from the lactobacillus paracasei ZY is good in palatability, digestion is promoted, and the immunity of the organism is enhanced.

The invention discloses a composition for treating insomnia. Comprising probiotic compounds: lactobacillus plantarum, bifidobacterium lactis, lactobacillus crispatus, lactobacillus acidophilus, lactobacillus rhamnosus, bifidobacterium bifidum, lactobacillus reuteri, lactobacillus casei, lactobacillus bulgaricus, lactobacillus fermentum, lactobacillus gasseri, lactococcus lactis, bifidobacterium longum, lactobacillus salivarius, bifidobacterium breve, streptococcus thermophilus and lactobacillus paracasei; lactobacillus helveticus; and traditional Chinese medicine components and prebiotics. Probiotics are matched with traditional Chinese medicines with homology of medicine and food, and corresponding prebiotics are supplemented, so that the balance of intestinal flora can be adjusted and information transmission between intestines and cranial nerves can be promoted through the synergistic effect of the probiotics and the corresponding prebiotics, and then gastrointestinal inflammation, ulcer, helicobacter pylori infection, constipation and insomnia are treated or improved; and treating or improving spleen and stomach disharmony, liver qi stagnation, excessive heart fire, fire excess from yin deficiency, heart-kidney disharmony caused by emotion, pressure, diseases and the like, and insomnia caused by the symptoms.

The invention discloses a lactobacillus casei KC88, and the preservation number of the lactobacillus casei KC88 is CGMCC (China General Microbiological Culture Collection Center) No.32107. Meanwhile, the invention also discloses a screening process and application of the strain. According to the lactobacillus casei KC88 provided by the invention, the expression of a Cdl gene with fusobacterium nucleatum can be down-regulated, and the expression of a Mgl gene of porphyromonas gingivalis can be down-regulated. At the same time, the lactobacillus casei KC88 can inhibit the production of pathogenic bacteria biological membranes and reduce the production of volatile sulfides. And the inactivated surface protein of the casei casei KC88 can inhibit the formation of a pathogenic bacterium biological membrane. Therefore, the lactobacillus casei KC88 viable bacteria and the thermally inactivated bacteria have the effects of relieving breath and improving gastrointestinal functions, and can be applied to the fields of medicines, health care products and the like.

The invention provides a halite-containing probiotic preparation for improving gastrointestinal environment and a preparation method, the halite-containing probiotic preparation comprises the following components in parts by weight: 60-70 parts of a probiotic composition, the probiotic composition comprises lactobacillus casei Zhang, animal bifidobacterium subsp. Lactis V9, lactobacillus plantarum P-01, animal bifidobacterium subsp. Lactis B-01 and casei paracasei LC-11, the weight ratio is 3: 2: 2: 1: 1. 1.2 to 3.5 parts of nanoscale refined halite; 10 to 15 parts of a microcapsule embedding material; 0.6 to 1.2 parts of an antioxidant system; 15 to 30 parts of auxiliary materials; the probiotic preparation disclosed by the invention has the characteristics of obvious strain combination advantage, nano-scale halite protection and synergism, accurate release of a multi-layer microcapsule structure, synergistic effect of an antioxidant system and the like, the survival rate of probiotics, gastrointestinal tract tolerance and intestinal colonization capacity are remarkably improved, and a new technical scheme is provided for improving gastrointestinal health.

The invention discloses an aquaculture denitrification microcapsule as well as a preparation method and application thereof, and relates to the technical field of aquaculture and biology. The lactobacillus casei provided by the invention can secrete acid metabolites, and the acid metabolites can inhibit pathogenic vibrio, so that the occurrence of diseases in aquaculture can be reduced. Lactobacillus casei has the efficacy of efficiently degrading ammonia nitrogen and nitrite nitrogen in the aquaculture environment, and can continuously realize efficient cleaning of the aquaculture environment. In addition, the invention also provides a denitrification microcapsule which creates a more favorable microenvironment for the efficient denitrification strain, so that the repeated denitrification performance is more stably exerted, and the denitrification microcapsule can be repeatedly utilized.

The present invention belongs to the technical fields of biological bacterium agents and functional food processing. Specifically, it relates to a bacterium agent for soybean milk fermentation and its application, a soy cheese stick and a preparation method thereof. The bacterium agent for soybean milk fermentation provided by the present invention uses Lactobacillus helveticus HL88 and Lactobacillus casei BL25 in combination. It can not only quickly acidify the soy milk, shortening the coagulation time of soy cheese, but also more fully hydrolyze soy proteins, releasing more short peptides and amino acids. In particular, it can highly produce γ-aminobutyric acid (GABA), enhancing the fermentation effect and nutritional value of soybean milk. Further, the soy cheese food prepared by fermenting with the above bacterium agent not only has a strong soy milk fragrance and a smooth texture, but is also easily digested and absorbed, improving the digestibility and reducing the soybean allergenicity, especially helping to improve exercise fatigue and enhance sleep quality. Therefore, the above bacterium agent provided by the present invention has excellent application prospects in the field of preparing functional foods for anti-fatigue and promoting sleep.

The invention belongs to the technical field of microorganisms, and particularly relates to a preservative and bacteriostatic metabiotic composition for food as well as a preparation method and application of the preservative and bacteriostatic metabiotic composition. The raw materials of the postbiotic composition comprise inactivated thalli of compound probiotics and metabolites of the compound probiotics; the compound probiotics comprise lactobacillus casei Zhang, bifidobacterium animalis subsp. Lactis V9, lactobacillus plantarum P-8 and lactobacillus plantarum PB-2. Through mutual cooperation of the four strains, a culture substrate can be more effectively converted into a plurality of organic acids and short-chain fatty acids with more excellent preservative and antibacterial effects, and the preservative and antibacterial effects of the post-biogen composition are improved.

The present invention relates to the technical field of probiotics, and in particular to a strain of Lactobacillus casei ZKLc1221, its lactobacillus and its application in improving ulcerative colitis. Lactobacillus casei )ZKLc1221 has been deposited in the General Microbiology Center of China Microorganism Culture Collection Committee on June 21, 2023, with the deposit address at No. 3, Yard No. 1, Beichen West Road, Chaoyang District, Beijing, and the deposit number is CGMCC No. 27673. The lactobacillus obtained by optimizing the fermentation conditions of Lactobacillus casei ZKLc1221 provided by the present invention has good thermal stability, good effect in improving ulcerative colitis, and can significantly improve pathological damage to the colon.

The invention discloses a compound probiotic for improving cognitive function of old people and a preparation method and application thereof. Firstly, maltodextrin is dried and then sieved, metal impurities are removed after sieving, and maltodextrin freeze-dried powder, lactobacillus paracasei Lpc37 freeze-dried powder, phytobacterium plantarum Lp-115 freeze-dried powder and bifidobacterium animalis subsp. Lactis Bl-04 freeze-dried powder are weighed and sieved respectively; the preparation method comprises the following steps: preparing freeze-dried powder of three strains, then premixing the freeze-dried powder of the three strains with a part of maltodextrin, adding the residual maltodextrin after the strains are premixed, continuously mixing until the materials are uniformly distributed to obtain the compound probiotics, exerting a synergistic effect through a specific strain combination (Lp115 + Lpc37 + Bl-04), providing a new way for non-drug intervention, being beneficial to regulating intestinal flora metabolism (such as generating short-chain fatty acid SCFA), and improving the immunity of the human body. The synthesis and release of neurotrophic factors are promoted, the nerve cell function is improved, and the cognitive function improvement is indirectly assisted.

The invention relates to a compound microorganism deodorization fungicide as well as a preparation method and application thereof, and belongs to the technical field of microorganism application. The invention provides a compound microorganism deodorization bacterium agent. The compound microorganism deodorization bacterium agent is prepared from bacillus cereus GXMU-Q5.3, streptomyces beihaiensis GXMU-J15 and lactobacillus paracasei GXMU-G1, the viable count ratio of the bacillus cereus GXMU-Q5.3 to the streptomyces beihaiensis GXMU-J15 to the lactobacillus paracasei GXMU-G1 is (1 to 2): (1 to 2): (1 to 2). The strain of the composite microbial deodorant agent is screened from soil and water at the stacking place of the marine product processing waste, the decomposition and deodorization effects on the marine product processing waste are obvious, the bacteria have a synergistic effect, and the deodorization effect of the composite microbial agent is improved by 40% or above compared with that of a single strain; the cost is low, the efficiency is high, the application range is wide, the deodorization period is short, and the safety is high.

The invention relates to the technical field of microorganisms, in particular to a probiotic composition for improving sleep and application, and the probiotic composition comprises lactobacillus paracasei BMC-2020, lactobacillus plantarum MCA-3066, lactobacillus rhamnosus, lactobacillus fermentum and lactobacillus casei. The probiotic composition provided by the invention is safe and efficient, has a prospect of developing a new medicine for improving sleep, and has a clinical practical value; the probiotic composition is used for fermenting the traditional Chinese medicine composition, the obtained traditional Chinese medicine fermentation composition contains probiotics and traditional Chinese medicine fermentation liquor, the probiotics and the traditional Chinese medicine fermentation liquor can effectively achieve a synergistic effect, and the sleep improving efficacy of a traditional Chinese medicine fermentation product is promoted; the traditional Chinese medicine fermented composition can reduce the awakening activity amount and the total awakening time, and has the effect of improving sleep.

The invention discloses a composite microecological preparation as well as a preparation method and application thereof. The compound microecological preparation disclosed by the invention comprises lactobacillus casei, lactobacillus plantarum and saccharomyces cerevisiae. The application effect of the composite microecological preparation in cow breeding is remarkable, the optimal addition amount of the composite microecological preparation is 100 mL / cow / day, the production performance of lactating cows can be improved, the milk yield is improved by 3.30 kg / cow / day, the milk yield of 4% standard milk is improved by 3.78 kg / cow / day, the total protein is improved by 15.9%, the albumin is improved by 14.7%, the globulin is improved by 16.5%, and the somatic cell number is reduced by 52.6%; and pollutant emission can be reduced, including 37.2% of ammonia emission reduction and 28.7% of carbon dioxide emission reduction.

The invention discloses application of lactobacillus paracasei S1 in relieving acute liver injury, and belongs to the technical field of microorganisms. The invention aims to provide application of lactobacillus paracasei S1 separated from fresh rumen fluid and applied to a product for relieving acute liver injury in relieving acute liver injury. The lactobacillus paracasei S1 disclosed by the invention is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC NO.33269. The lactobacillus paracasei S1 disclosed by the invention is a lactobacillus paracasei S1 strain. According to the lactobacillus paracasei S1 disclosed by the invention, AST, ALT, GGT and GDH activities of serum of mice with acute liver injury are reduced, and the condition of liver injury is improved. In conclusion, the lactobacillus paracasei S1 can be used for improving the acute liver injury or applied to feed, food and health care products, and a scientific basis is provided for developing functional products related to the lactobacillus paracasei S1 for improving the acute liver injury in the future.

The invention belongs to the technical field of probiotic products, and particularly relates to lactobacillus rhamnosus JM039 as well as a composition and application thereof. The preservation number of the lactobacillus rhamnosus JM039 is GDMCC No: 64409. The lactobacillus rhamnosus JM039 is a lactobacillus rhamnosus strain. The composition is prepared from lactobacillus reuteri J1, lactobacillus gasseri JM1, lactobacillus paracasei JY062, lactobacillus paracasei with the preservation number of GDMCC.No.62990, lactobacillus plantarum JY039 and lactobacillus rhamnosus JM039, and is prepared from lactobacillus reuteri J1, lactobacillus gasseri JM1, lactobacillus paracasei JY062, lactobacillus paracasei with the preservation number of GDMCC.No.62990, lactobacillus plantarum The combined bacteria of the six probiotics can improve the levels of anti-inflammatory factors and intestinal epithelium tight junction proteins and reduce the levels of proinflammatory factors and claudin-2 mRNA, so that the intestinal microenvironment homeostasis and intestinal barrier integrity are maintained through double regulation of inflammatory factors and tight junction proteins, and necrotizing enterocolitis can be relieved.

The use and composition of a postbiotic of Lactobacillus paracasei ET-22, and the use of a lysate derived from Lactobacillus paracasei ET-22 in freshening breath and / or alleviating or inhibiting halitosis. The lysate is derived from heat-inactivated bacterial cells of Lactobacillus paracasei ET-22, the lysate at least comprises 2-hydroxy-3-phenylpropionic acid, NAD and a polypeptide, and the polypeptide has a structure as represented by formula 1. The postbiotic of and the lysate derived from Lactobacillus paracasei ET-22 can significantly reduce the contents of breath volatile sulfur compounds (VSCs) and salivary volatile organic compounds (VOCs) in the oral cavity, reduce the contents of characteristic flavor compounds, such as indoles, propionic acid and hexanoic acid, and can alter the oral microflora and inhibit the growth of oral biofilms and pathogenic bacteria, thus having the effects of freshening breath and alleviating or inhibiting halitosis.

The present invention belongs to the field of microbial technology, and specifically relates to a postbiotic composition for anti-corrosion and antibacterial in food, its preparation method and application. The raw materials of the postbiotic composition include: inactivated cells of a compound probiotic and metabolites of the compound probiotic; the compound probiotic includes Lactobacillus casei Zhang, Bifidobacterium animalis subsp. lactis V9, Lactobacillus plantarum P-8 and Lactobacillus plantarum PB-2. Through the mutual cooperation of the above four strains, the present invention can more effectively convert the culture medium substrate into several organic acids and short-chain fatty acids with more excellent anti-corrosion and antibacterial effects, improving the anti-corrosion and antibacterial effects of the postbiotic composition.

The object of the present invention is to use the strain of bacteria named Lacticaseibacillus paracasei DG® CNCM I-1572 DSM 34154 for use in a method of treating dysbiosis, particularly in patients with IBS (Irritable Bowel Syndrome), preferably without constipation, who have high fecal levels of Collinsella aerofaciens.

The invention provides a cordyceps militaris fermentation extract and application thereof in preservation of agaricus bisporus, and belongs to the technical field of deep processing of edible mushrooms and preservation of agricultural products. The preparation method of the cordyceps militaris fermentation extract comprises the following steps: (1) taking cordyceps militaris sporocarp, adding water, grinding, and performing enzymolysis by using cellulase and papain in sequence to obtain cordyceps militaris pulp; (2) adding glucose and waste beer yeast powder into the cordyceps militaris pulp, then inoculating lactobacillus paracasei and bifidobacterium bifidum, and fermenting; and (3) after fermentation is completed, carrying out ultrasonic crushing, centrifuging to remove thalli, and carrying out spray drying to obtain the cordyceps militaris fermentation extract. The method can effectively reduce the browning index and weight loss ratio of agaricus bisporus, can slow down the increase of malonaldehyde, reduces the activity of PPO enzyme, and prevents enzymatic browning caused by the synergistic effect of the PPO enzyme and peroxidase. The SOD enzyme activity in the agaricus bisporus can be kept, active oxygen in tissues can be removed, and the metabolic balance of the active oxygen can be maintained.

The invention discloses lactobacillus paracasei and belongs to the technical field of microorganisms. The lactobacillus paracasei is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation address is Beijing, China, the preservation number is CGMCC No.26029, and the preservation date is November 2, 2022. The lactobacillus paracasei has the advantages that the lactobacillus paracasei can be used for preparing the lactobacillus paracasei, and the lactobacillus paracasei can be used for preparing the lactobacillus paracasei; the lactobacillus paracasei capable of effectively relieving constipation and preventing aging through the antioxidant function of the lactobacillus paracasei is obtained for the first time, and the lactobacillus paracasei has the advantages of being convenient to eat, simple in treatment, high in relieving rate and free of toxic and side effects.

Provided is a composition for controlling uptake of microparticles into a body, the composition containing a lactic acid bacterium. The lactic acid bacterium is preferably any one selected from bacteria belonging to the genus Lactobacillus and bacteria belonging to the genus Streptococcus. For example, the lactic acid bacterium is a bacterium belonging to Lactobacillus delbrueckii, Lactobacillus paracasei, Lactobacillus gasseri, or Streptococcus thermophilus.

The invention discloses a method for fermenting sunflower bee pollen by using compound lactic acid bacteria and application of the sunflower bee pollen, and belongs to the technical field of fine and deep processing of bee products. The fermentation method comprises the following steps: inoculating compound lactic acid bacteria into sunflower bee pollen for fermentation; the preparation method of the compound lactic acid bacteria comprises the step of compounding lactobacillus plantarum and lactobacillus casei according to the volume ratio of (2 to 1) to (5 to 1), so as to obtain the compound lactic acid bacteria. The compound lactobacillus fermentation method suitable for the sunflower bee pollen is established for the first time, a new way is provided for high-value utilization of the bee pollen, and theoretical support is provided for breaking through the bottleneck of a bee pollen processing technology and developing an innovative bee pollen product with high absorptivity, high activity and pleasant flavor.

The invention relates to the field of microorganisms, and particularly discloses lactobacillus paracasei YT805 and application thereof. The strain is separated from fermented yak milk, is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation address is No.3, No.1 yard, Beichen West Road, Chaoyang District, Beijing, the preservation number is CGMCC No.31830, the preservation date is September 3, 2024, and the strain is identified as Lactobacillus paracasei. The strain can efficiently and specifically metabolize and utilize inulin, can be used for preparing various fermented products containing prebiotic inulin, and is beneficial to improving intestinal microecological balance, enhancing immunity and promoting nutrient absorption.

The invention relates to bacteria of the species Lactobacillus paracasei and / or compositions comprising Lactobacillus paracasei for use in preventing and / or treating a mental illness, a symptom affecting mental health and / or a condition associated with chronic stress, in a mammal. The invention further relates to methods and uses of said bacteria of the species Lactobacillus paracasei and / or compositions. The invention can be applied in restoring, maintaining, and / or promoting mental (including cognitive) health and has potential applications, inter alia, in the area of dietary and food supplements, medicaments and pharmaceuticals.

The invention relates to the technical field of functional food production through microbial fermentation, in particular to a herba epimedii enzymolysis probiotic fermentation refined extract and a preparation method thereof.The preparation method comprises the following steps that herba epimedii and beta-cyclodextrin are mixed, an obtained mixed solution is subjected to enzymolysis treatment through pectinase, cellulase and glycosidase and then serves as a solid-state fermentation substrate, and the herba epimedii enzymolysis probiotic fermentation refined extract is obtained; adding mixed bacteria of lactobacillus casei, bifidobacterium lactis and lactobacillus gasseri, performing solid-state fermentation, and performing vacuum freeze drying to obtain a herba epimedii probiotic fermentation refined extract; the herba epimedii probiotic fermentation refined extract is prepared by adopting an enzymolysis fermentation method in cooperation with a beta-cyclodextrin inclusion technology, the extraction efficiency, the solubility, the biological activity, the stability and other performance of effective components in herba epimedii are improved, the preparation method is simple, and operation is easy and convenient; the used materials are edible, green and safe; the process saves energy consumption, has good environmental benefits, greatly saves manpower and material resources, and can be applied to industrial large-scale production.

The invention belongs to the technical field of biology, and particularly relates to a composition with anti-hair-loss and hair-growing effects and a preparation method and application thereof. The preparation method provided by the invention comprises the following steps: standing and culturing composite lactobacillus consisting of lactobacillus plantarum, lactobacillus paracasei and lactobacillus bulgaricus according to a volume ratio of (12-15): (3-5): (4-8) to obtain a seed solution, further inoculating the seed solution into a fermentation culture medium containing polygonum multiflorum, ginseng leaves and cacumen biotae, standing and culturing to obtain a fermentation medium containing polygonum multiflorum, ginseng leaves and cacumen biotae; the composition with the anti-hair-loss and hair-growing effects is obtained. The composition prepared by the method disclosed by the invention is rich in flavone, polyphenol and other hair-growing and hair-loss-preventing active ingredients, and has good hair-loss-preventing, hair-growing, hair-brightening and hair-repairing effects.

The invention discloses a lactobacillus casei strain capable of inhibiting activity of Chromarospora sp. And application of the lactobacillus casei strain in green pepper storage. The invention provides lactobacillus casei GHY-4, and the preservation registration number of the lactobacillus casei GHY-4 is CGMCC (China General Microbiological Culture Collection Center) No.31925. Furthermore, the invention provides a microbial agent of the lactobacillus casei GHY-4. The invention also protects the application of the lactobacillus casei GHY-4 or the microbial inoculum in inhibition of alternaria alternata. The invention also protects the application of the lactobacillus casei GHY-4 or the microbial inoculum in fresh keeping of green peppers. The method can be used for fresh keeping of the green peppers and has application and popularization values for the green pepper industry.

The invention belongs to the related technical field of pet prescription food products, and particularly relates to a prescription food for pet dogs with acute intestinal inflammation and a preparation method of the prescription food, the prescription food comprises various components such as rice, barley, chicken powder and corn protein powder, and probiotics are self-made and comprise bifidobacterium, lactobacillus acidophilus and lactobacillus casei. The preparation method comprises the steps of quantitative raw material weighing, auxiliary agent grinding, constant-temperature accurate grinding, adding of specific components for accurate grinding again, heat preservation, deodorization and degassing, drop casting forming, cooling, packaging, sealed storage and the like. Compared with the prior art, the prescription food is high in safety, and feeding tests of healthy dogs have no abnormity; clinical cases show that the leucocyte number and the inflammatory factor content of sick dogs can be reduced; the intestinal barrier can be repaired, so that the intestinal mucosa repair is accelerated; intestinal flora can be improved, and the content of short-chain fatty acid in excrement is increased; the nutrition state can be maintained, and the weight loss range of sick dogs is reduced.

The invention relates to a polygonatum sibiricum probiotic compound preparation with an aging delaying effect and application thereof. The compound preparation comprises a polygonatum sibiricum extract and a probiotic composition, the bacterial strains in the probiotic composition comprise a combination of a bifidobacterium animalis subsp. Lactis BLa36 bacterial strain, a bifidobacterium longum BL21 bacterial strain, a bifidobacterium adolescentis BAC30 bacterial strain, a lactobacillus plantarum Lp90 bacterial strain, a lactobacillus casei LC89 bacterial strain, a bifidobacterium breve BBr60 bacterial strain and a pediococcus acidilactici CCFM7902 bacterial strain. After the rhizoma polygonati component and the probiotic component are combined for use, the rhizoma polygonati component and the probiotic component have potential synergistic effects in the aspects of improving the intestinal flora structure, regulating the intestinal environment, delaying senescence, reducing inflammation-related symptoms and the like. Moreover, further, various probiotic strains are compounded and combined for use, so that the capability of a related compound preparation in the aspect of delaying various symptoms of senescence can also be improved in a combined manner.