515 results about "Allergy" patented technology

The invention relates to the technical field of medical treatment, in particular to a multi-parameter collaborative infusion process intelligent monitoring and priority calling method, which comprises the following steps of: acquiring four-dimensional monitoring data through a liquid level pressure sensor array, an infrared dripping speed detection module, a flexible temperature patch and a photoelectric heart rate sensor, and combining an LSTM (Long Short Term Memory) anomaly prediction model, and outputting the pipeline state score, the allergy risk index and the infusion progress prediction value in real time. And generating a real-time risk value through a weight configuration mechanism and stage identification logic, judging a risk level according to a dynamic threshold value, and outputting a corresponding early warning level signal. And the system further maps the early warning level signals into common, emergency and critical call instructions, and distributes the common, emergency and critical call instructions to a multi-channel execution terminal to construct a multi-level linkage response mechanism of closed-loop feedback. According to the invention, the accuracy and response efficiency of infusion risk identification can be significantly improved, and the method is suitable for intelligent reconstruction and automatic early warning response scenes of a clinical nursing information system.

The invention relates to a whitening and anti-aging composition suitable for sensitive skin and application of the whitening and anti-aging composition, and belongs to the technical field of cosmetics. The composition comprises bakuchiol, hydrolyzed royal jelly protein, a radix pseudostellariae extract and a golden camellia flower extract as active ingredients. The bakuchiol has the effects of resisting aging, resisting oxidation, resisting inflammation and the like; the hydrolyzed royal jelly protein can help to relieve skin discomfort, preserve moisture, enhance the skin barrier function and the like; the golden camellia flower extract has the effects of resisting light aging, whitening skin, fading spots, resisting inflammation and relieving allergy, and the radix pseudostellariae extract has the effects of resisting inflammation, resisting oxidation, resisting aging and the like. According to the composition disclosed by the invention, through reasonable blending of the components, synergistic interaction can be realized, the effects of resisting inflammation, whitening and delaying senescence are remarkably improved, and the composition contains natural components, is mild and non-irritant, is suitable for sensitive skin and can be applied to various cosmetics.

The invention provides a viscose large biological fiber with an anti-allergy function and a preparation method thereof, and belongs to the field of viscose fibers. The preparation method of the viscose large biological fiber with the anti-allergy function comprises the following steps: preparing a molecular nest, preparing modified gel, coating and forming, preparing a spinning solution, and spinning and forming. According to the preparation method of the viscose large biological fiber with the anti-allergy function, the problem that the activity and the stability of adopted plant active ingredients are reduced due to the fact that the adopted plant active ingredients are affected by process environments, solvent ingredients and the like can be solved; meanwhile, the release characteristic of the plant active ingredients in the viscose fibers can be regulated and controlled according to needs, so that the plant active ingredients are released in a large dose within a short time or slowly released in a small dose within a long time, and then emergent repair or long-acting allergy relief of skin allergy areas is achieved.

The invention is suitable for the technical field of anti-allergy agents, and provides an anti-allergy agent containing compound plant anti-allergy active ingredients. Comprising 5-10 parts of a bletilla striata extract, 8-15 parts of an aloe extract, 7-12 parts of an angelica sinensis extract, 10-20 parts of a centella asiatica extract, 5-15 parts of a rosemary extract, 8-18 parts of a polygonum cuspidatum extract, 12-25 parts of a scutellaria baicalensis extract, 3-10 parts of a tea extract, 6-15 parts of a liquorice extract and 4-12 parts of a matricaria recutita extract. The preparation method of the anti-allergy agent containing the compound plant anti-allergy active ingredients comprises the following steps: step 1, extracting and concentrating in groups; step 2, compounding additional ingredients; and step 3, mixing and forming the preparation. The anti-allergy agent containing the compound plant anti-allergy active component is specifically applied to allergic rhinitis nasal spray, postoperative wound repair, pet skin anti-allergy spray, anti-allergy baby clothes treating agent, low-allergy household cleaning agent and air purification spray. And through the synergistic effect of multiple targets and multiple channels, the balanced synergism of the repairing effect and the relieving effect is realized.

Novel, inexpensive, and highly effective methods and devices for convenient and effective wound irrigation are described herein. Methods and devices disclosed herein utilize a synergistic combination of two or more antiseptic agents to reduce contact time, enhance antimicrobial effects, and reduce the likelihood of allergy and other side effects from the antiseptic agents in subjects. In one embodiment, devices include a discharge means for a reservoir housing containing irrigation solution wherein the discharge means has one or more specifically designed nozzles through which a sufficient volume of the irrigation solution can pass at an appropriate pressure.

The invention relates to the technical field of artificial intelligence, and discloses a system of a nutrition recipe recommendation system based on artificial intelligence in chronic disease intervention management and an application method. Comprising a data acquisition module, a data preprocessing and feature engineering module, a knowledge base management module, a personalized nutritional requirement modeling module, a recipe generation and optimization module, a user interface module and a model training and updating module which are in communication connection through a network. According to the method, personalized health data such as physiological indexes, chronic disease characteristics, diet preference, allergy and intolerance information of a user are collected in multiple dimensions, a nonlinear relation between the characteristics of the user and nutritional requirements is deeply mined in combination with a deep learning model, and an accurate personalized nutritional requirement model is generated according to specific illness conditions and body indexes of different chronic disease patients; therefore, recipe recommendation conforming to individual differences is provided, and the risk of aggravating the illness state due to improper diet is reduced.

The invention provides a polypeptide compound and application thereof, and belongs to the technical field of medical or dressing preparations. According to the invention, three specific polypeptides are synergistically proportioned to obtain the polypeptide compound, and the polypeptide compound has the effect of repairing a skin basement membrane in a targeted manner. The polypeptide compound has the advantages of being small in molecular weight, high in safety, low in allergy risk and high in permeability, and has excellent repairing and anti-aging functions. Experiments prove that the polypeptide compound provided by the invention, as an active peptide raw material, can remarkably promote the production of endogenous collagen IV, VII and XVII of skin, is also beneficial to repairing skin extracellular matrix, resisting DNA damage, improving skin cycle protein, inhibiting release of inflammatory factors and the like, can effectively repair a basement membrane, and has a wide application prospect.

The invention provides an eye drop composition as well as a preparation method and application thereof, and belongs to the technical field of ophthalmic preparations. The eye drop composition adopted by the invention is prepared from the following components: brimonidine tartrate, hyaluronic acid, collagen, trehalose and injection water. By compounding the components, the eye drops which can realize slow release of brimonidine tartrate and prolong the antihypertensive action time and have the characteristics of relieving blink discomfort, long-acting moisturizing, anti-inflammatory soothing, mildness, corrosion prevention and the like are prepared; the eye drops are beneficial to people suffering from glaucoma, intraocular hypertension, xerophthalmia, postoperative inflammation or allergy and preservative sensitivity or preservative allergy, the life quality is improved, and diseases are relieved.

The invention provides eye protection liquid for improving eye microcirculation and a preparation method thereof, and belongs to the technical field of medical configuration products. The composition comprises the following components: surface-modified magnetic nanoparticles, a calendula extract, a fermented dogwood extract, xanthophyll, taurine, sodium hyaluronate, hydrolyzed sodium hyaluronate, soya bean lecithin, borneol and fermented vegetable oil. The efficiency of active ingredients is improved through a double-fermentation technology, magnetic targeting and multi-channel compounding are combined, and the preparation method has remarkable advantages in the field of improving periorbital microcirculation. The traditional Chinese medicine composition has an obvious relieving effect on asthenopia and dry skin around eyes; the components of the eye microcirculation eye protection liquid are mild, and adverse reactions such as allergy cannot be caused.

The invention discloses purple perilla plant milk rich in strontium element and a preparation process thereof. The purple perilla plant milk is prepared from the following raw materials: shelled purple perilla seeds, shelled flaxseeds, peeled cyperus esculentus, sesame, soybeans, peas and strontium-rich water. The preparation method mainly comprises the following steps: raw material pretreatment, fine wet grinding, filtering and deslagging, high-pressure homogenization and refinement, ultrahigh-temperature instantaneous sterilization and sterile filling. The method ensures the fine taste, stability and safety of the product. The plant milk is rich in strontium element and high-quality plant protein, does not contain lactose and cholesterol, and has the advantages of bone health maintenance, low sensitivity and the like. The problems that casein allergy and lactose intolerance risks exist in traditional animal milk, and existing plant milk is low in protein content, unbalanced in nutrition, dependent on additives and single in function are solved.

The invention discloses an intelligent patient safety risk reminding method and system based on PACS and RIS, and the method comprises the steps: collecting the multi-source medical data of HIS, EMR, LIS and the like in real time through an HL7 and DICOM multi-protocol fusion technology, constructing a dynamic evaluation model covering the core risks of allergy, metal implants, infectious diseases and the like, and carrying out the native integration of a hierarchical reminding mechanism at PACS and RIS workstations. The system adopts a Bayesian network model to realize dynamic adjustment of risk levels, a differentiated reminding interface is embedded through a webpage style technology, and risk reminding of each level forcibly requires a doctor to confirm and process. And the closed-loop feedback module records the medical care operation and returns the medical care operation to a related system, and continuously optimizes the risk assessment model. The problems that an existing system is isolated in data, single in reminding function and incomplete in risk coverage are solved, the clinical risk management level is remarkably improved, and the medical accident rate is reduced.

The invention discloses an anti-wrinkle firming face cream based on camellia oleosa seed oil diglyceride and a preparation method of the anti-wrinkle firming face cream. The anti-wrinkle firming face cream is prepared from deionized water, glycerin, butanediol, sodium hyaluronate, camellia oleosa seed oil diglyceride, squalane, simmondsia chinensis seed oil, cetearyl glucoside, glyceryl stearate, acetyl hexapeptide-8, palmitoyl tripeptide-1, vitamin E, 1, 2, 4-trimethyl-1, 3-pentanediol and a proper amount of water. The component A is prepared from 1, 2-hexanediol, caprylyl glycol, a thickening agent and a pH regulator; in the aspect of efficacy, through the synergistic effect of the camellia oleosa seed oil diglyceride, the acetyl hexapeptide-8, the palmitoyl tripeptide-1 and the vitamin E, efficient anti-wrinkle tightening is achieved; in the aspect of skin feeling, squalane and jojoba oil are matched with a light emulsifying system and trace xanthan gum, so that velvet matte texture is made, and the velvet is soft, smooth and not sticky; in the aspect of safety, 1, 2-hexanediol and caprylyl glycol which are safe and free of sensitization are used for corrosion prevention, no irritating component is generated, the anti-allergic skin care lotion is suitable for various skin types, the allergy risk is reduced, and reliable and comfortable skin care experience is brought to consumers.

The invention relates to the technical field of purification, in particular to Chinese cabbage moss allergy-free factor purification equipment which comprises an outer box, one side of the outer box is communicated with a feeding pipe, a self-cleaning filtering assembly capable of automatically scraping impurities attached to different side faces is arranged in the outer box, and the self-cleaning filtering assembly comprises a filtering cylinder rotationally connected with the side wall of the outer box; one side of the filter cartridge is communicated with a transverse pipe, the transverse pipe extends to the outside of the outer box, the feeding pipe penetrates through the transverse pipe, a scraping assembly is arranged in the filter cartridge, the scraping assembly is dragged to rise when the filter cartridge rotates and then slides down to conduct scraping, a driving assembly used for driving the transverse pipe and the filter cartridge to rotate is arranged on the outer box, and the scraping assembly comprises an arc-shaped plate in sliding connection with the inner wall of the filter cartridge; and a plurality of sliding plates are fixedly connected between the two arc-shaped plates. The technical problems that particles in Chinese cabbage moss juice of existing purification equipment are prone to blocking a filter screen, the amount of blocked Chinese cabbage moss particles is large, the cleaning difficulty is increased, and the process of cleaning the filter screen is time-consuming and labor-consuming are solved.

An automated food recognition platform comprises a memory, processor, and various submodules, utilizing artificial intelligence to analyze digital media (images, photos, audiovisual) for food identification and attributes. It includes an edible food database and recipe submodule, generating personalized recipes considering dietary preferences. The automated food recognition platform also features allergy and drug interaction submodules, informing users of relevant information. A marketplace submodule tracks inventory levels, enhancing recipe recommendations. Leftover identification and meal planning submodules offer creative cooking solutions. An interactive submodule fosters a chef-user community, incorporating user feedback and social media data to refine recipe recommendations. Chefs receive compensation based on a chef rating, determined by user interactions. The platform promotes chef recipes through paid advertising services within the interactive submodule.

A method for improving gut microbiota population in a subject by administering a composition comprising allulose, erythritol or a combination thereof. A method for increasing one or more colonic bacterial populations from the families Lachnospiraceae or Eubacteriaceae by administering a composition comprising allulose, erythritol or a combination thereof. A method for preventing, treating or ameliorating a disease in a subject by administering a composition comprising allulose, erythritol or a combination thereof. The disease may be one or more of metabolic syndrome, obesity, type 2 diabetes, insulin resistance, hyperlipoproteinemia, hyperuricemia, hepatic steatosis, hypercholesterolemia, hypertriglyceridemia, irritable bowel syndrome (IBS), colon cancer, allergy, non-alcoholic fatty liver disease, inflammatory bowel disease, cardiovascular disease, or inflammation. The bacterial population may be the species Anaerostipes hadrus, Blautia obeum, Anaerobutyricum hallii, Eubacterium rectale (Agathobacter rectalis), Eubacterium callanderi, Eubacterium limosum and Eubacterium maltosivorans. A composition comprising allulose, erythritol or a combination thereof and one or more colonic bacterial populations from the families Lachnospiraceae or Eubacteriaceae is also provided. The composition may in the form of a food composition.

The invention belongs to the field of traditional Chinese medicine extracts, and provides a dendrobium extract as well as a preparation method and application thereof. Comprising the following preparation steps: extracting herba artemisiae scopariae with a solvent, enriching anti-bacteriostatic components in the herba artemisiae scopariae, mixing herba dendrobii with the herba artemisiae scopariae extract in proportion, extracting with a solvent, and purifying, refining, filtering and sterilizing an extracting solution through a chromatographic column, so as to prepare the herba dendrobii extract without the preservative, and the herba dendrobii extract can be applied to daily chemical products, medicines and health-care foods. And the shelf life can reach more than 24 months. The dendrobium extract prepared by the preparation method provided by the invention does not need to be added with traditional preservatives, so that the problems of irritation, allergy and the like caused by the preservatives are avoided, and the soothing and anti-inflammatory effects can also be improved.

The invention relates to a traditional Chinese medicine composition for preventing and treating liver rupture syndrome of broiler breeders and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following raw material medicines in parts by mass: 50-200 parts of silybum marianum, 50-200 parts of schisandra chinensis, 50-200 parts of gentiana macrophylla, 50-200 parts of andrographis paniculata, 50-200 parts of radix paeoniae alba, 50-200 parts of oldenlandia diffusa, 50-200 parts of folium isatidis and 50-200 parts of patrinia. The traditional Chinese medicine composition has the effects of resisting endotoxin, inflammation, allergy and liver injury and the like, and effectively prevents and treats the liver rupture syndrome of the broiler breeders.

The invention belongs to the technical field of traditional Chinese medicines, mainly relates to a preparation method of herbal ointment, and in particular relates to a preparation method and application of specific endowment herbal ointment. The formula disclosed by the invention comprises herbal fermentation liquor, herbal enzymatic hydrolysate and herbal extracting liquor, wherein the herbal fermentation liquor is obtained by fermenting mint, purple perilla, chrysanthemum, radix angelicae and pericarpium citri reticulatae through probiotics and then filtering; the herbal enzymatic hydrolysate is obtained by performing enzymolysis and extraction on semen armeniacae amarae and poria cocos; the herbal extracting solution is obtained by extracting smoked plum, lily and liquorice with water. The herbal ointment prepared by the invention has the effects of resisting allergy, relieving itching, diminishing swelling and relieving eczema and rhinitis.

The invention belongs to the technical field of cosmetics, and particularly relates to whitening and freckle-removing essence oil and a preparation method thereof. According to the invention, adamantane formyl is introduced into an alpha-arbutin benzene ring to obtain the adamantane formyl modified alpha-arbutin derivative, so that the compatibility of alpha-arbutin and base oil is enhanced; the alpha-arbutin is prevented from being converted into hydroquinone by utilizing the large steric effect of adamantane formyl, so that the safety of the whitening and freckle-removing essence oil is improved; the tranexamic acid is wrapped by the ceramide nano-emulsion, so that the skin allergy risk caused by ingestion of the tranexamic acid is reduced; the ceramide nano-emulsion and tranexamic acid act together to repair skin collagenous fibers, block melanin transfer and inhibit melanin synthesis; trilinolein and glabridin are catalyzed by lipase to form a compound, so that the molecular compatibility and photo-thermal stability of glabridin are enhanced; glycerin promotes transdermal absorption of glabridin and enhances the efficacy of the whitening and freckle-removing essence oil.

The invention discloses recombinant human VII type collagen as well as a preparation method and application thereof, and belongs to the technical field of biochemical engineering. The recombinant human VII type collagen comprises a plurality of amino acid residue repetitive units shown as SEQ ID NO.1. Compared with natural VII type collagen, the recombinant human VII type collagen obtained by repeating the repetitive units for multiple times has the advantages that the molecular weight is smaller, the sequence is more easily and efficiently secreted and expressed in a pichia pastoris system after optimization, and the recombinant human VII type collagen can be used for preparing the recombinant human VII type collagen. The method has the characteristics of high yield, low cost, simplicity in operation and easiness in large-scale production. Meanwhile, the anti-oxidation activity is excellent, the skin moisturizing and repairing capacity and the wound healing capacity are promoted, due to the fact that the collagen is derived from human collagen, the risks of allergy and rejection reaction can be remarkably reduced, and the safety is extremely high. Therefore, the recombinant collagen can be used as a core active component to be widely applied to the fields of cosmetics, medicines and the like, and has a good application prospect.

The use of 2'-fucosyllactose in the preparation of a food / drug for promoting intestinal glycocalyx development and preventing intestinal glycocalyx damage caused by lipopolysaccharide (LPS). The use of 2'-fucosyllactose in the preparation of a food / drug for the adjuvant treatment and / or adjuvant prevention of gastrointestinal infections, inflammatory bowel diseases, obesity or allergy caused by glycocalyx damage. Before adherent growth of Caco-2 cells, adding 2'-FL for co-culture with the Caco-2 cells can simulate the intestinal growth and maturation state. In the state, 2'-FL can significantly promote the development of the glycocalyx layer of Caco-2 cells, and can further prevent the glycocalyx layer damage caused by LPS on this basis.

The invention discloses a composition and application thereof, and the composition comprises synephrine or a pharmaceutically acceptable salt thereof, and further comprises naringin, neohesperidin and / or hesperidin. The composition prepared by compounding the synephrine or the pharmaceutically acceptable salt thereof with the naringin, the neohesperidin and / or the hesperidin has the effects of relieving, repairing, resisting wrinkles, easing pain, relieving itching or resisting allergy when being used as a functional component of a skin care product; when being used as a functional component of a scalp care product, the shampoo has the effects of removing dandruff, removing oil, relieving itching or preventing alopecia.

The disclosure relates to compounds of the disclosure and pharmaceutically acceptable salts thereof to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The compounds of the disclosure may be useful in the treatment, prevention, suppression and amelioration of disease(s) such as atopic dermatitis, eosinophilic gastritis, atopic keratoconjunctivitis, allergy, alopecia, Alzheimer's disease, asthma, atherosclerosis, Bechet's disease, bullous pemphigoid, cancer, chronic obstructive pulmonary disease, chronic pruritis, chronic urticaria, Crohn's disease (CD), dermatitis, diabetic kidney disease, eosinophilic esophagitis, fungal keratitis, gout, idiopathic pulmonary fibrosis (IPF), keloids, non-alcoholic steatohepatitis (NASH), primary biliary cirrhosis, prurigo nodularis, psoriasis, psoriatic arthritis, rhinosinusitis, scleroderma, systemic lupus erythematosus (SLE), systemic sclerosis, ulcerative colitis (UC), vitiligo, or hidradenitis suppurativa. The compounds of the disclosure may be useful in the treatment, prevention, suppression and amelioration of a dermatological condition or a respiratory condition.

The invention relates to a medicine for promoting skin injury repair and healing and a preparation method thereof, and belongs to the technical field of biological medicines.The medicine is prepared from a radix astragali preparata extract, lipidosome encapsulated panax notoginseng total saponin-RGD peptide, a honeysuckle flower-maca extract, an asiaticoside-hydroxypropyl-beta-cyclodextrin inclusion compound and dipotassium glycyrrhizinate; the radix astragali preparata extract is a product obtained by moistening radix astragali with honey, baking, extracting with deionized water, and adsorbing and purifying with a Sephadex G-15 column; the honeysuckle-maca extract is a product obtained by mixing dry honeysuckle powder and dry maca root powder according to the mass ratio of (3-5): (1-1.7), performing enzymolysis through cellulase, then performing common enzymolysis through ficin protease and papain, and performing adsorption and purification through an HPD722 macroporous adsorption resin column. All the components are compatible according to a specific proportion, so that the allergy and skin irritation risks are reduced, skin injury healing is reasonably promoted, and melanin deposition is effectively inhibited.

The present disclosure provides methods for treating, preventing, or ameliorating one or more symptoms of birch allergy or allergic disease in a subject by administering to the subject two antibodies or antigen-binding fragments thereof that bind Bet v 1, or a cocktail of two antibodies or antigen-binding fragments thereof that bind Bet v 1.

To enable high-sensitivity detection of chicken that might cause allergies contained in food ingredients and products even if the amount is minute.SOLUTION: A method of detecting chicken is provided, comprising extracting protein from a sample, obtaining an enzyme digest of the extracted protein using a protease, and analyzing the enzyme digest to detect at least one peptide of SEQ ID NO: 1 using a mass spectrometer so as to qualitatively or quantitatively determine the presence or absence of chicken protein in the sample.SELECTED DRAWING: Figure 1

The invention relates to the technical field of cat litter production, in particular to a tea residue cat litter and a preparation method thereof.The tea residue cat litter comprises a functional layer, a protective layer and a water-soluble film layer; the functional layer is prepared from the following raw materials: tea residue powder, an antibacterial agent, powder essence, a binder, composite powder and deionized water; the raw material of the protective layer consists of composite powder; the water-soluble film layer is formed by drying water-soluble slurry; the composite powder comprises modified zeolite, bentonite and sodium bicarbonate. The tea residue cat litter provided by the invention is endowed with antibacterial, deodorizing and aroma-emitting effects on the functional layer; the protective layer is endowed with the function of a protective functional layer, so that the problems of allergy and the like caused by direct contact between an antibacterial agent and the skin of the cat are avoided; the water-soluble film layer is endowed with a sealing effect, so that on one hand, dust drifting in a room can be reduced, and on the other hand, the smell emitted by the essence can be greatly reduced, and cats and consumers can accept the essence easily; through compounding of a multi-layer structure, the overall quality of the tea residue cat litter is improved.

The disclosure relates to a series of substituted imidazolecarboxamide compounds of formula I as BTK (Bruton's Tyrosine Kinase) inhibitors, and the methods of using the same for the treatment of autoimmune disease, inflammatory disease, cancer and potentially allergies.

The present invention relates to the use of certain polyacrylamide gel formulations to treat conditions where cartilage has degraded and / or where exposed collagen is present. The invention further relates to the prophylactic use of such formulations to prevent degradation, or further degradation, of cartilage and / or collagen. Additionally, the invention also includes substituting such certain polyacrylamide gel formulations in lieu of carboxymethylcellulose, or alternatively HA, in individuals and mammals having allergies, sensitivities, or other adverse reactions to such compounds. Additionally, the invention further relates to the use of the polyacrylamide gel formulations for the controlled release of therapeutic agents and / or as a medical scaffold or matrix for biological therapies.

The system according to the embodiment aims to generate appropriate recipes taking into consideration the health information, allergy information, and refrigerator inventory information of family members. [Solution] A system according to an embodiment includes an input unit, an acquisition unit, a generation unit, and a provision unit. The input unit inputs health information or allergy information of family members and dietary needs. The acquisition unit acquires refrigerator inventory information. The generation unit generates a recipe based on the information obtained by the input unit and the acquisition unit. The provision unit provides the recipe generated by the generation unit.