268 results about "Allergy" patented technology

The invention relates to the technical field of artificial intelligence, and discloses a system of a nutrition recipe recommendation system based on artificial intelligence in chronic disease intervention management and an application method. Comprising a data acquisition module, a data preprocessing and feature engineering module, a knowledge base management module, a personalized nutritional requirement modeling module, a recipe generation and optimization module, a user interface module and a model training and updating module which are in communication connection through a network. According to the method, personalized health data such as physiological indexes, chronic disease characteristics, diet preference, allergy and intolerance information of a user are collected in multiple dimensions, a nonlinear relation between the characteristics of the user and nutritional requirements is deeply mined in combination with a deep learning model, and an accurate personalized nutritional requirement model is generated according to specific illness conditions and body indexes of different chronic disease patients; therefore, recipe recommendation conforming to individual differences is provided, and the risk of aggravating the illness state due to improper diet is reduced.

The invention relates to the technical field of purification, in particular to Chinese cabbage moss allergy-free factor purification equipment which comprises an outer box, one side of the outer box is communicated with a feeding pipe, a self-cleaning filtering assembly capable of automatically scraping impurities attached to different side faces is arranged in the outer box, and the self-cleaning filtering assembly comprises a filtering cylinder rotationally connected with the side wall of the outer box; one side of the filter cartridge is communicated with a transverse pipe, the transverse pipe extends to the outside of the outer box, the feeding pipe penetrates through the transverse pipe, a scraping assembly is arranged in the filter cartridge, the scraping assembly is dragged to rise when the filter cartridge rotates and then slides down to conduct scraping, a driving assembly used for driving the transverse pipe and the filter cartridge to rotate is arranged on the outer box, and the scraping assembly comprises an arc-shaped plate in sliding connection with the inner wall of the filter cartridge; and a plurality of sliding plates are fixedly connected between the two arc-shaped plates. The technical problems that particles in Chinese cabbage moss juice of existing purification equipment are prone to blocking a filter screen, the amount of blocked Chinese cabbage moss particles is large, the cleaning difficulty is increased, and the process of cleaning the filter screen is time-consuming and labor-consuming are solved.

The invention discloses recombinant human VII type collagen as well as a preparation method and application thereof, and belongs to the technical field of biochemical engineering. The recombinant human VII type collagen comprises a plurality of amino acid residue repetitive units shown as SEQ ID NO.1. Compared with natural VII type collagen, the recombinant human VII type collagen obtained by repeating the repetitive units for multiple times has the advantages that the molecular weight is smaller, the sequence is more easily and efficiently secreted and expressed in a pichia pastoris system after optimization, and the recombinant human VII type collagen can be used for preparing the recombinant human VII type collagen. The method has the characteristics of high yield, low cost, simplicity in operation and easiness in large-scale production. Meanwhile, the anti-oxidation activity is excellent, the skin moisturizing and repairing capacity and the wound healing capacity are promoted, due to the fact that the collagen is derived from human collagen, the risks of allergy and rejection reaction can be remarkably reduced, and the safety is extremely high. Therefore, the recombinant collagen can be used as a core active component to be widely applied to the fields of cosmetics, medicines and the like, and has a good application prospect.

The disclosure relates to a series of substituted imidazolecarboxamide compounds of formula I as BTK (Bruton's Tyrosine Kinase) inhibitors, and the methods of using the same for the treatment of autoimmune disease, inflammatory disease, cancer and potentially allergies.

The system according to the embodiment aims to generate appropriate recipes taking into consideration the health information, allergy information, and refrigerator inventory information of family members. [Solution] A system according to an embodiment includes an input unit, an acquisition unit, a generation unit, and a provision unit. The input unit inputs health information or allergy information of family members and dietary needs. The acquisition unit acquires refrigerator inventory information. The generation unit generates a recipe based on the information obtained by the input unit and the acquisition unit. The provision unit provides the recipe generated by the generation unit.

The utility model provides a novel medical application adhesive tape which comprises a base layer and further comprises an adhesive layer with one side adhered to the base layer and release paper separably adhered to the other side of the adhesive layer, a plurality of transverse tearing lines and longitudinal tearing lines are arranged on the release paper, and base layer tearing lines corresponding to the longitudinal tearing lines are arranged on the base layer. A plurality of air holes are formed in the base layer in an array mode, the base layer is coated with the adhesive layer in a latticed mode, the adhesive layer is arranged to avoid the air holes, the base layer is coated with the adhesive layer in a rectangular latticed mode, and the air holes are formed in the base layer in a rectangular array mode. The novel medical application adhesive tape provided by the utility model not only is safe and reliable to paste wounds at different parts, has a better using effect, but also has better air permeability, and relieves uncomfortable symptoms such as skin allergy, redness, itching and the like which are easily caused by long-time use.

The invention relates to the technical field of external traditional Chinese medicine plasters, in particular to a yang-activating, cold-removing and pain-relieving ointment and a preparation method thereof. The analgesic ointment is prepared by taking black sesame oil and yellow lead as matrixes and assisting coarse medicinal materials with the effects of warming yang, dispelling cold, promoting blood circulation and dredging collaterals and fine medicinal materials (musk, camphor, myrrh, frankincense and the like) through the steps of treating the medicinal materials, extracting, refining oil, adding the yellow lead to form the ointment, removing fire toxin, adding the fine materials, spreading and the like. The traditional Chinese medicine composition does not contain western medicine components, can warm yang and dredge vessels, dispel cold and wind and eliminate dampness, promote blood circulation to remove meridian obstruction and remove blood stasis, and relieve swelling and pain, and is suitable for treating various orthopedic and rheumatism diseases such as acute and chronic lumbar and cervical diseases, knee joint hyperosteogeny, sciatica and scapulohumeral periarthritis. The ointment is large in drug loading capacity, capable of being administrated for a long time, good in long-term curative effect, not prone to relapse after healing, capable of being directly applied without heating, convenient to use, free of deterioration in two years at the normal temperature, small in irritation, low in anaphylaxis and high in safety.

The invention discloses a composition and a cosmetic with anti-allergy, itching-relieving and redness-removing effects. The composition is prepared from the following raw material components: a herba centellae extract with madecassoside content of not less than 85wt%, a dendrobium officinale stem extract and dihydrooat acyl o-aminobenzoic acid. The composition comprising the three components is added into the cosmetic, so that the cosmetic has good system stability, also has enhanced anti-allergy, itching-relieving and red-removing effects, and can improve skin problems from multiple dimensions.

The application provides a postoperative wound nursing device for a rehabilitation medicine department and belongs to the technical field of medical devices. The device comprises a fixing plate, a plurality of compression assemblies are arranged on the outer side of the fixing plate, the compression assembly comprises a sleeve rod rotationally connected with the fixing plate, an extension rod is slidably arranged in the sleeve rod, a compression block is arranged at the end of the extension rod away from the fixing plate, a tension spring is fixedly arranged at the end of the extension rod in the sleeve rod, an installation groove is arranged at the end of the compression block away from the extension rod, a bandage is fixedly arranged in the installation groove, and an adjusting assembly is arranged on the upper end of the fixing plate. In the above scheme, the compression block and the inclined bandage can strongly extrude and occlude the edges of the gauze, so that the gauze is prevented from sliding and lifting, the traditional adhesive tape is replaced, the problems of easy falling off, allergy and glue residue of the adhesive tape after long-time sticking are solved, the wound is reliably covered all the time, and the secondary infection of the wound is prevented.

The invention provides a corn stigma extract-containing mask mud with repairing, anti-wrinkle and freckle-removing effects and a preparation method thereof, and relates to the technical field of cosmetics. The mask mud is prepared from the following raw materials: corn stigma extract, guava fruit extract, white willow bark extract, tamarix chinensis flower extract, sulfonic acid hydroxypropyl ester lauryl glucoside cross-linked polymer sodium and auxiliary materials. The corn stigma extract is taken as a main raw material, and the three natural extracts, namely the guava fruit extract, the white willow bark extract and the tamarix chinensis flower extract, are compounded according to a specific proportion, so that multiple effects of resisting wrinkles, removing acnes, whitening, resisting allergy, repairing, removing freckles, tightening, moisturizing, soothing and the like are realized at the same time, and the effect of the corn stigma extract is remarkably improved; sulfonic acid hydroxypropyl ester lauryl glucoside cross-linked polymer sodium is used as a surfactant, so that the lotion is milder and more moisturizing, no preservative is added, and damages such as skin irritation, allergy, red and swollen skin, cuticle damage and dry skin are reduced.

The invention provides a double-layer collagen scaffold repair membrane as well as a preparation method and application thereof, and the preparation method comprises the following steps: extracting collagen from animal fur, and emulsifying to obtain a collagen emulsion; adding a cross-linking agent into the collagen emulsion, and emulsifying to obtain a cross-linked protein emulsion; pouring the cross-linked protein emulsion into a mold, and freeze-drying to obtain a cross-linked protein layer; and pouring the collagen emulsion on the cross-linked protein layer, and freeze-drying to obtain the double-layer collagen scaffold repair membrane. The repairing membrane is excellent in structure, the cross-linked protein layer provides mechanical strength and supporting performance, the collagen layer can be rapidly dissolved and attached to the contact surface, and oxygen exchange and metabolite discharge of the wound surface are facilitated; the collagen is high in purity, low in antigenicity and high in safety, any toxic and harmful chemical reagents and preservatives are not added, allergy or inflammatory reaction is avoided, and the collagen has good application prospects in the fields of medical treatment, medical beauty, beauty, skin care and the like.

A system is provided.SOLUTION: A system, comprising: means for a user to input his / her allergy information; means for a terminal to verify and store the inputted allergy information; means for the terminal to photograph an appearance of a store and identify the store; means for a server to obtain menu information of the identified store; means for the server to filter menus based on the allergy information of the user; and means for the terminal to display the filtered menu information.SELECTED DRAWING: Figure 1

This invention discloses a strain of Bifidobacterium animalis subspecies TRT-2A with allergy-relieving effects and its extracellular vesicle applications. The strain TRT-2A is deposited at the China Center for Type Culture Collection (CCTCC) on November 21, 2025, with accession number CCTCC NO:M 20252645. This strain is highly acid-resistant and exhibits good tolerance to artificial gastric and intestinal fluids. It effectively inhibits bacteria, particularly Streptococcus pyogenes, Streptococcus agalactiae, and / or Escherichia coli. Experimental results show that this strain can alleviate hormone-dependent dermatitis and effectively improve dermatitis symptoms such as erythema and desquamation. Furthermore, extracellular vesicles prepared using TRT-2A can effectively improve skin elasticity and reduce wrinkles. Therefore, the Bifidobacterium animalis subspecies TRT-2A of this invention has multiple functions and is worthy of further promotion and application.

Administration of pentadecanoylcarnitine or pentadecanoic acid is provided for prevention, management or treatment of aggression, allergies, allergic rhinitis, Alzheimer's disease, anxiety and anxiety disorders, amyotrophic lateral sclerosis, arthritis, asthma, atherosclerosis, attention-deficit hyperactivity disorder, bipoloar disorder, brain damage, cancer, cardiovascular disease, cholestatic pruritis, depression, chronic obstructive pulmonary disease (COPD), cocaine abuse, cough, dermatitis, depression, drug-seeking behavior, gastrointestinal disorders, facial erythema associated with rosacea, glaucoma, hepatic diseases, hyperactive bladder, hypersensitivity disorders, hypertension, impulsivity, inflammation, mental disorders and conditions, metabolic disorders, migraines, nasal and sinus congestion, nausea, neuropathic pain with and symptoms of multiple sclerosis, neurological and neuropsychiatric disorders, obesity, obsessive-compulsive disorders, opioid-induced respiratory depression, osteoarthritis, pain, Parkinson disease, pathological gambling, peptic ulcers, schizophrenia, sleep disorders, spinal cord injury, tardive dyskinesia, tics and behavioral problems with Tourette's syndrome; as well as for supporting appetite, cardiovascular health, hematologic health, memory, metabolic health, mood, prolonged REM sleep, renal health, sexuality, sociability and metabolic, hematological, renal, and weight loss.

The present invention provides novel drug-linker conjugates and antibody-drug conjugates of imidazo quinoline amine derivatives, which have agonistic activity against Toll-like receptors (TLRs), in particular TLR7 and / or TLR8, also provided are pharmaceutical compositions and methods of treatment against certain diseases or conditions mediated by or associated with TLR7 and / or TLR8 (e.g., graft rejection, autoimmunity, inflammation, allergy, asthma, infection, sepsis, cancer, and immunodeficiency).

The invention discloses a construction method and application of a machin allergic rhinitis animal model, and belongs to the field of disease animal model construction. According to the method, house dust mites are firstly used for sensitization, then 10% hydrogen peroxide and house dust mites are combined for excitation modeling, the 10% hydrogen peroxide destroys nasal mucosa and accelerates occurrence of allergic rhinitis, and the monkeys with allergic rhinitis are obtained after 13 periods of modeling. According to the method, the animal model which is highly similar to human allergic rhinitis in behavior, inflammatory symptom and phenotype is successfully constructed. The model provides guarantee for observing nasal symptoms and rhinitis behaviors of allergic rhinitis, inducing an organism to generate allergy-related immune response, establishing a sensitization basis, simulating a pathogenesis process, researching pathogenesis of allergic rhinitis, screening allergic rhinitis drugs and the like.

We provide the system. [Solution] A means of converting voice input from a user into text data, A means for generating recipes based on the user's age, skill level, allergy information, and available ingredients, Means for displaying the generated recipe as visual and audio instructions, A means of monitoring user actions and detecting dangerous situations, Means of issuing warnings for detected dangers, A system that includes this.

The present disclosure relates to a vaccine comprising at least one peptide antigen conjugate having the formula selected from PEG-[E1]-A-[E2]-[U]-H and H-[U]-[E1]-A-[E2]-PEG, wherein E1 is an N terminal extension, E2 is a C terminal extension, A is peptide antigen, H is hydrobhobic block, wherein one or more drug molecules (D) are optionally attached to each H directly or via a suitable linker X1; U is a linker, [ ] denotes the group is optional and - denotes that the two adjacent groups are directly attached to one another by a covalent bond or indirectly to one another via a suitable linker X. The vaccine is useful in treating or preventing a cancer, an autoimmune disease, an allergy, or an infectious disease.

The present invention provides a novel antigen for soy allergy, a diagnostic method and kit for soy allergy, a pharmaceutical composition containing the antigen, soybeans or soybean products from which the antigen has been removed, and a tester for determining the presence or absence of soybean antigen in a target object. [Solution] A polypeptide is provided which comprises a polypeptide containing at least one amino acid sequence selected from a specific group, which specifically binds to IgE antibodies in patients with polypeptide allergies, and which has 500 or fewer amino acid residues.

The application provides a liver hydatid disease screening method and system based on plain CT and deep learning, belongs to the technical field of intelligent medical treatment, and realizes liver hydatid disease identification based on plain CT by combining a liver segmentation model, a liver hydatid lesion identification model and a liver hydatid screening model, reduces the risk of patients of intake of more radiation due to enhanced CT, reduces the risk of patients of allergy due to injection of contrast agent, and has strong clinical applicability; can realize patient-level diagnosis on the basis of slice-level identification, classification and segmentation, and has interpretability; in combination with the real situation of hydatid disease in clinical diagnosis and treatment and the clinical characteristics of hydatid disease, the identification accuracy is greatly improved, and in addition, the population including healthy people can be identified and screened, and the use range is wide.

The invention belongs to the technical field of plasters, and particularly relates to a plaster with long-term one-way moisture conduction performance and a preparation method of the plaster. After a backing layer of an original plaster is punched and subjected to oxygen / air plasma treatment, a large-molecular-weight polymer and a small-molecular-weight hydrophilic liquid reagent are sequentially applied to be combined, and the plaster with the long-term one-way moisture conduction performance is obtained. In-situ construction of a hydrophilic film on the inner surface of a hole of the drug matrix layer is carried out in cooperation with super-hydrophilic modification of the backing layer. The plaster patch disclosed by the invention can obtain long-term and efficient one-way moisture conduction and one-way perspiration functions on the premise of not influencing the drug effect, and the problems of discomfort and allergy of skin are avoided.

The invention relates to the technical field of cosmetics, in particular to a preservative-free cosmetic composition for barrier repair as well as a preparation method and application of the preservative-free cosmetic composition. The invention relates to a preservative-free cosmetic composition for barrier repair, which comprises the following components in percentage by weight: 4.0-6.0% of 1, 2-pentanediol; 0.5% to 1.0% of 1, 2-hexanediol; 0.1% to 0.5% of cerayl; 0.5%-1.0% of phytosterol; 4.0%-6.0% of stearic acid; 4.0%-7.0% of hydrogenated lecithin; 0 to 0.3 percent of caryophylline; 0-0.2% of a eucommia ulmoides bark extract; and the balance of water. The composition of 1, 2-pentanediol and 1, 2-hexanediol is adopted to replace a traditional chemical preservative, and on the premise that the preservative effect is achieved, the possibility of causing skin irritation and allergy risks is reduced; ceramide and phytosterol can participate in construction of a skin barrier and supplement and repair a lipid structure of the skin barrier; stearic acid and hydrogenated lecithin form a stable emulsification basis, so that the two long-term contradictory requirements of no chemical preservative stimulation and effective barrier repair are met, and the unification of product safety and efficacy is realized.

The utility model discloses a navel patch, which comprises a navel patch body, an adhesive tape, a first adhesive tape and a second adhesive tape, and is characterized in that the navel patch body is provided with opposite inner and outer sides; the medicine core is arranged in the navel patch body, the medicine core is provided with a protruding part, the protruding part protrudes out of the inner side of the navel patch body, and the protruding part is attached to the navel of a user; and the protective cover is buckled on the navel patch body and covers the convex part of the medicine core. According to the utility model, the warm compress and the medicine core are integrally combined, so that the volatilization of the medicine effect is improved, and the product effect is improved; the protective cover prevents the medicine core from being squeezed in the transportation process and dirt caused in the packaging process, the medicine core is fixed by the breathable protective film, the protective film plays a role in fixing the medicine core and preventing the medicine core from moving, the problem that the medicine core is difficult to clean due to the fact that the medicine core falls into the navel hole is solved, and the breathable holes can effectively keep skin breathable and avoid skin allergy.

Lipidized oxoadenines of formula (I) are TLR7 / 8 receptor ligands useful for modulating immune responses. These compounds may have therapeutic applications in the treatment of cancer, infectious diseases, allergies, or autoimmune disorders (SEE FORMULA).

This invention discloses a composition for relieving allergies, itching, and improving rough skin, its preparation method, and its application. The composition comprises the following active ingredients: asiaticoside, centella asiatica extract, kava extract, aescin, allantoin, and sodium hyaluronate. This invention prepares the composition using raw materials and proportions containing asiaticoside, centella asiatica extract, kava extract, aescin, allantoin, and sodium hyaluronate. The synergistic effect between these components results in excellent anti-allergic, anti-itch, and skin-roughening effects. After preparing the composition into a soothing and anti-itch cream, tests showed that it significantly reduced the a* value and lactic acid stinging score of sensitive skin. Doctor evaluation methods further confirmed its significant improvement effects on burning, erythema, swelling, peeling, stinging, and itching of sensitive skin, while also showing a significant effect on improving rough skin.

Lipidated oxoadenines of formula (I) are TLR7 / 8 receptor ligands useful for modulating immune responses. The compounds may have therapeutic application in the treatment of cancer, infectious diseases, allergy, or autoimmune disorders.

The invention relates to the technical field of toy materials, in particular to antibacterial and mildewproof plasticine and a preparation method thereof, and the antibacterial and mildewproof plasticine specifically comprises the following components in parts by weight: 40-50 parts of starch, 20-25 parts of glycerol, 3-5 parts of polyethylene glycol, 0.5-0.8 part of an emulsifier, 5-8 parts of sodium chloride, 5-8 parts of hydrogen peroxide, 0.1-0.3 part of potassium sorbate, 0.2-0.3 part of phenoxyethanol, 3-7 parts of a composite nanoparticle material and 15-20 parts of water. The plasticine mostly adopts food-grade raw materials, is non-toxic and harmless, can guarantee the safety of a user, can reduce the allergy risk of children, can effectively inhibit bacterium breeding and avoid mildewing and deterioration of the plasticine by adding potassium sorbate, is suitable for long-term storage or multi-user use scenes, and has a good market prospect. In addition, a special composite nano-particle material is adopted as a carrier to load phenoxyethanol, so that the antibacterial aging can be effectively prolonged, and the long-term antibacterial effect is realized.

Provided is an infant cereal product with reduced allergenic potential which can reduce the risk of allergy development in infants.

The invention discloses a medicine patch, and relates to the technical field of medical patches, the medicine patch comprises a backing layer, and a heating layer, a medicine layer and a slow-release layer which are arranged on the backing layer, the heating layer and the slow-release layer are respectively arranged on two sides of the medicine layer, the slow-release layer is used for being in contact with skin, and the medicine layer is arranged on the backing layer. The heating layer can generate a heating reaction after being in contact with air and maintain the heating reaction within a preset time period. The use comfort can be improved, the risk of allergy is reduced, and the medicine absorption effect is improved.