746 results about "Allergy" patented technology

The invention belongs to the technical field of preparation of microorganisms and cosmetics, and particularly relates to a strain composition, radix paeoniae rubra fermentation liquor prepared from the strain composition and application of the strain composition in cosmetics. Specifically, Pseudoalteromonas sp. SE9 and Schizoscharomyces pombe JM2-16 are utilized to perform fermentation treatment on radix paeoniae rubra root powder, and the finally obtained radix paeoniae rubra fermentation liquor has multiple effects of resisting oxidation, promoting proliferation and migration of keratinocytes, promoting skin injury repair, resisting allergy, resisting inflammation, relieving and the like, is high in safety, can be used as a cosmetic component, and can be used as a cosmetic preparation. Therefore, the method has good practical application value.

To provide beta-1,3-glucan, and to provide uses thereof for regulating immunity in the human body, which are methods for treating and / or preventing high cholesterol, diabetes, and allergies, and methods for treating and / or preventing intestinal inflammation.SOLUTION: Provided is a composition for oral administration for alleviating symptoms associated with intestinal inflammation in humans, the composition containing an effective amount of beta-1,3-glucan dried to a moisture content of about 40% or less from Euglena grown by fermentation, the beta-1,3-glucan not containing beta-1,6-glycosidic bonds, the effective amount being between 0.1 mg of beta-1,3-glucan / kg body weight and 100 mg of beta-1,3-glucan / kg body weight.SELECTED DRAWING: Figure 1

The invention relates to the technical field of medical treatment, in particular to a multi-parameter collaborative infusion process intelligent monitoring and priority calling method, which comprises the following steps of: acquiring four-dimensional monitoring data through a liquid level pressure sensor array, an infrared dripping speed detection module, a flexible temperature patch and a photoelectric heart rate sensor, and combining an LSTM (Long Short Term Memory) anomaly prediction model, and outputting the pipeline state score, the allergy risk index and the infusion progress prediction value in real time. And generating a real-time risk value through a weight configuration mechanism and stage identification logic, judging a risk level according to a dynamic threshold value, and outputting a corresponding early warning level signal. And the system further maps the early warning level signals into common, emergency and critical call instructions, and distributes the common, emergency and critical call instructions to a multi-channel execution terminal to construct a multi-level linkage response mechanism of closed-loop feedback. According to the invention, the accuracy and response efficiency of infusion risk identification can be significantly improved, and the method is suitable for intelligent reconstruction and automatic early warning response scenes of a clinical nursing information system.

The invention relates to a whitening and anti-aging composition suitable for sensitive skin and application of the whitening and anti-aging composition, and belongs to the technical field of cosmetics. The composition comprises bakuchiol, hydrolyzed royal jelly protein, a radix pseudostellariae extract and a golden camellia flower extract as active ingredients. The bakuchiol has the effects of resisting aging, resisting oxidation, resisting inflammation and the like; the hydrolyzed royal jelly protein can help to relieve skin discomfort, preserve moisture, enhance the skin barrier function and the like; the golden camellia flower extract has the effects of resisting light aging, whitening skin, fading spots, resisting inflammation and relieving allergy, and the radix pseudostellariae extract has the effects of resisting inflammation, resisting oxidation, resisting aging and the like. According to the composition disclosed by the invention, through reasonable blending of the components, synergistic interaction can be realized, the effects of resisting inflammation, whitening and delaying senescence are remarkably improved, and the composition contains natural components, is mild and non-irritant, is suitable for sensitive skin and can be applied to various cosmetics.

The invention discloses an adverse drug reaction monitoring and early warning system, which relates to the technical field of drug monitoring and early warning, and comprises a physiological data acquisition module, a drug risk grade evaluation module, a comprehensive monitoring module and a comprehensive early warning module, the data acquisition module is used for acquiring multi-dimensional patient physiological data including organ monitoring data, allergy monitoring data, metabolism monitoring data and drug heat monitoring data, and preprocessing the physiological data; according to the system, a multi-module cooperation technology, a multivariate data acquisition technology and a modern information technology are closely combined, real-time and comprehensive monitoring of the adverse drug reaction is achieved, through cooperation of all the modules, the risk level of the adverse drug reaction is evaluated, and the risk level of the adverse drug reaction is evaluated. Evaluating the risk level of the adverse drug reaction, and sending out a corresponding early warning signal according to an evaluation result.

The invention provides a viscose large biological fiber with an anti-allergy function and a preparation method thereof, and belongs to the field of viscose fibers. The preparation method of the viscose large biological fiber with the anti-allergy function comprises the following steps: preparing a molecular nest, preparing modified gel, coating and forming, preparing a spinning solution, and spinning and forming. According to the preparation method of the viscose large biological fiber with the anti-allergy function, the problem that the activity and the stability of adopted plant active ingredients are reduced due to the fact that the adopted plant active ingredients are affected by process environments, solvent ingredients and the like can be solved; meanwhile, the release characteristic of the plant active ingredients in the viscose fibers can be regulated and controlled according to needs, so that the plant active ingredients are released in a large dose within a short time or slowly released in a small dose within a long time, and then emergent repair or long-acting allergy relief of skin allergy areas is achieved.

The invention is suitable for the technical field of anti-allergy agents, and provides an anti-allergy agent containing compound plant anti-allergy active ingredients. Comprising 5-10 parts of a bletilla striata extract, 8-15 parts of an aloe extract, 7-12 parts of an angelica sinensis extract, 10-20 parts of a centella asiatica extract, 5-15 parts of a rosemary extract, 8-18 parts of a polygonum cuspidatum extract, 12-25 parts of a scutellaria baicalensis extract, 3-10 parts of a tea extract, 6-15 parts of a liquorice extract and 4-12 parts of a matricaria recutita extract. The preparation method of the anti-allergy agent containing the compound plant anti-allergy active ingredients comprises the following steps: step 1, extracting and concentrating in groups; step 2, compounding additional ingredients; and step 3, mixing and forming the preparation. The anti-allergy agent containing the compound plant anti-allergy active component is specifically applied to allergic rhinitis nasal spray, postoperative wound repair, pet skin anti-allergy spray, anti-allergy baby clothes treating agent, low-allergy household cleaning agent and air purification spray. And through the synergistic effect of multiple targets and multiple channels, the balanced synergism of the repairing effect and the relieving effect is realized.

The invention discloses an external traditional Chinese medicine mixture aiming at genital skin mucosa ulceration wound repair and a preparation method thereof, relates to the field of traditional Chinese medicines, and aims to provide a genital skin mucosa ulceration wound repair medicine which has the effects of promoting wound repair and relieving itching, and is simple in component, small in allergy probability, light and thin in dosage form and good in skin feeling. The traditional Chinese medicine mixture is prepared from chicken butter, honeysuckle stem, felwort, cortex dictamni, fructus kochiae, radix scutellariae, cortex phellodendri, angelica sinensis, radix rehmanniae, radix arnebiae seu lithospermi, sanguisorba officinalis and bletilla striata. The traditional Chinese medicine mixture disclosed by the invention realizes simultaneous treatment of pruritus vulvae and ulceration, fills the treatment blank, relieves symptoms as soon as possible, shortens the treatment cycle and saves expenditure. The curative effect is prominent, and current clinical requirements are met. Cost and loss are reduced. Preparation is convenient, high-end machines are not needed, and preparation can be carried out at home.

The invention relates to a Lactobacillus paracasei LC97, and an application, a product and a method thereof, and belongs to the technical field of microorganisms. The preservation number of the lactobacillus paracasei LC97 for relieving allergy is CGMCC (China General Microbiological Culture Collection Center) NO. 32421. Based on the strain, the invention also provides application and related products of the strain. The LC97 strain has broad-spectrum antibacterial performance, has the functions of enhancing immune function and relieving atopic dermatitis, and can relieve atopic dermatitis by relieving skin lesion, inhibiting inflammation, reducing ear swelling degree and regulating cell factor level. And by reducing the total levels of serum IgE and IL-4, the levels of IFN-gamma and IL-10 are improved, and the levels of cytokines are regulated, so that the immunity is enhanced.

Novel, inexpensive, and highly effective methods and devices for convenient and effective wound irrigation are described herein. Methods and devices disclosed herein utilize a synergistic combination of two or more antiseptic agents to reduce contact time, enhance antimicrobial effects, and reduce the likelihood of allergy and other side effects from the antiseptic agents in subjects. In one embodiment, devices include a discharge means for a reservoir housing containing irrigation solution wherein the discharge means has one or more specifically designed nozzles through which a sufficient volume of the irrigation solution can pass at an appropriate pressure.

To provide a system that includes: means that proposes recipes that take into consideration allergies, food preferences, and activity levels of a child, gets information about special offers at nearby supermarkets, and proposes recipes that use affordable and seasonal ingredients; and means that accumulates images of food ingredient lists, when allergic symptoms appear, AI will suggest which ingredients are suspected.SOLUTION: The system includes: means for proposing recipes that take into account allergies, food preferences, and physical activity levels of a child; means of getting information about special offers at nearby supermarkets, and means of proposing recipes that use affordable and seasonal ingredients; and means that accumulates images of the ingredients of foods consumed, and when allergic symptoms appear, AI suggests which ingredients are suspected.SELECTED DRAWING: Figure 1

The invention relates to the technical field of artificial intelligence, and discloses a system of a nutrition recipe recommendation system based on artificial intelligence in chronic disease intervention management and an application method. Comprising a data acquisition module, a data preprocessing and feature engineering module, a knowledge base management module, a personalized nutritional requirement modeling module, a recipe generation and optimization module, a user interface module and a model training and updating module which are in communication connection through a network. According to the method, personalized health data such as physiological indexes, chronic disease characteristics, diet preference, allergy and intolerance information of a user are collected in multiple dimensions, a nonlinear relation between the characteristics of the user and nutritional requirements is deeply mined in combination with a deep learning model, and an accurate personalized nutritional requirement model is generated according to specific illness conditions and body indexes of different chronic disease patients; therefore, recipe recommendation conforming to individual differences is provided, and the risk of aggravating the illness state due to improper diet is reduced.

The invention provides a polypeptide compound and application thereof, and belongs to the technical field of medical or dressing preparations. According to the invention, three specific polypeptides are synergistically proportioned to obtain the polypeptide compound, and the polypeptide compound has the effect of repairing a skin basement membrane in a targeted manner. The polypeptide compound has the advantages of being small in molecular weight, high in safety, low in allergy risk and high in permeability, and has excellent repairing and anti-aging functions. Experiments prove that the polypeptide compound provided by the invention, as an active peptide raw material, can remarkably promote the production of endogenous collagen IV, VII and XVII of skin, is also beneficial to repairing skin extracellular matrix, resisting DNA damage, improving skin cycle protein, inhibiting release of inflammatory factors and the like, can effectively repair a basement membrane, and has a wide application prospect.

The present invention discloses salts of a Compound 1:useful in the prophylaxis and / or treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving degradation and / or disruption of cartilage homeostasis, congenital cartilage malformations, and / or diseases associated with hypersecretion of IL6 or interferons.

The invention relates to a skin care composition containing perigord truffle and plant exosome and application of the skin care composition. The skin care composition containing perigord truffle and plant exosome comprises perigord truffle extract, chlorella exosome, malachite extract, fermentation product filtrate and soluble collagen. The fermentation product filtrate comprises any one or a combination of at least two of a Thermus thermophilus fermentation product, a lactobacillus / soybean milk fermentation product filtrate or a lactobacillus / mung bean seed extract / sodium glutamate fermentation product filtrate. The perigord truffle extract, the chlorella exosome, the malachite extract, the fermentation product filtrate and the soluble collagen are creatively combined to form the composition with the whitening, anti-allergy and anti-oxidation effects, and the composition has the effects of inhibiting melanin synthesis, relieving skin inflammation response, whitening skin, resisting allergy and resisting oxidation. And an unexpected synergistic effect is achieved in the aspects of oxidation resistance and aging resistance. The composition is mild in performance and free of irritation and toxic and side effects, and can be applied to cosmetic products more safely.

The invention discloses bifidobacterium breve BBr26 capable of inhibiting hyaluronidase activity and relieving allergy as well as an application, a product and a method of the bifidobacterium breve BBr26, and belongs to the technical field of microorganisms. The invention provides a Bifidobacterium breve (Bifidobacterium breve) strain BBr26 with anti-allergy and / or immunoregulation capability, and the preservation number of the Bifidobacterium breve strain BBr26 is CGMCC (China General Microbiological Culture Collection Center) NO.32424. The invention also provides a preparation method of the Bifidobacterium breve strain The invention also provides an application of the strain bifidobacterium breve BBr26 in preparation of products for relieving atopic dermatitis, and / or food for enhancing immune function, and / or bacteriostatic agents, and a product and a method based on the strain BBr26. The strain disclosed by the invention has broad-spectrum bacteriostasis, can relieve allergy and atopic dermatitis, and can effectively play a role in immunoregulation.

The invention discloses a preparation method and application of a marine high-molecular polysaccharide hydrogel wound dressing. The hydrogel is formed by cross-linking the marine polysaccharide composition and the cross-linking agent, and the gelation time is short and is about 15 seconds; pores are uniform and moderate; the self-healing property, the adhesion property and the swelling property are high; the antibacterial effect is strong, and the inhibition rates on escherichia coli and staphylococcus aureus are both higher than 90%; skin irritation and skin allergy are avoided, and the biological safety is high; hemostasis can be rapidly carried out within 10s, and the bleeding amount is obviously reduced; the hydrogel dressing can rapidly shrink and scab a wound surface, has the effect of promoting wound healing, and has the effects of stopping bleeding and promoting wound healing which are obviously superior to those of commercially available hydrogel dressings (German Hydrosorb Gel) (Plt; 0.05), and is a safe and effective high-performance wound dressing. In addition, the hydrogel is simple in formula and high in industrialization prospect, is expected to be developed into novel wound dressings and medical instruments, and breaks through the trapping that domestic hydrogel dressings are mostly dependent on import.

The invention provides an eye drop composition as well as a preparation method and application thereof, and belongs to the technical field of ophthalmic preparations. The eye drop composition adopted by the invention is prepared from the following components: brimonidine tartrate, hyaluronic acid, collagen, trehalose and injection water. By compounding the components, the eye drops which can realize slow release of brimonidine tartrate and prolong the antihypertensive action time and have the characteristics of relieving blink discomfort, long-acting moisturizing, anti-inflammatory soothing, mildness, corrosion prevention and the like are prepared; the eye drops are beneficial to people suffering from glaucoma, intraocular hypertension, xerophthalmia, postoperative inflammation or allergy and preservative sensitivity or preservative allergy, the life quality is improved, and diseases are relieved.

The invention provides eye protection liquid for improving eye microcirculation and a preparation method thereof, and belongs to the technical field of medical configuration products. The composition comprises the following components: surface-modified magnetic nanoparticles, a calendula extract, a fermented dogwood extract, xanthophyll, taurine, sodium hyaluronate, hydrolyzed sodium hyaluronate, soya bean lecithin, borneol and fermented vegetable oil. The efficiency of active ingredients is improved through a double-fermentation technology, magnetic targeting and multi-channel compounding are combined, and the preparation method has remarkable advantages in the field of improving periorbital microcirculation. The traditional Chinese medicine composition has an obvious relieving effect on asthenopia and dry skin around eyes; the components of the eye microcirculation eye protection liquid are mild, and adverse reactions such as allergy cannot be caused.

The invention discloses a thermal spring water composition for relieving itching and soothing skin and a preparation method of the thermal spring water composition, and belongs to the technical field of itching relieving and soothing. Chitosan has good film-forming property, after chitosan, mung bean protein and the like form a compound, after the compound is smeared on the surface of skin, a layer of relatively stable protective film with certain air permeability can be constructed, skin allergy and inflammatory reaction can be reduced, a relatively wet microenvironment is formed on the surface of the skin, and the skin care effect is improved. The moisture loss of the skin is reduced, and the moisture balance of the skin is favorably kept, so that uncomfortable symptoms such as dry and tight skin are relieved, and the skin is further promoted to be relieved; after the centella asiatica polysaccharide is subjected to carboxymethylation modification, the water solubility and the biological activity of the centella asiatica polysaccharide are remarkably improved, and the carboxymethylated centella asiatica polysaccharide and the mung bean protein-chitosan compound have a synergistic effect, so that the barrier function of skin can be enhanced, the metabolism of skin cells can be regulated, and the skin can be effectively protected. The repair and regeneration of damaged skin cells are promoted.

The invention discloses purple perilla plant milk rich in strontium element and a preparation process thereof. The purple perilla plant milk is prepared from the following raw materials: shelled purple perilla seeds, shelled flaxseeds, peeled cyperus esculentus, sesame, soybeans, peas and strontium-rich water. The preparation method mainly comprises the following steps: raw material pretreatment, fine wet grinding, filtering and deslagging, high-pressure homogenization and refinement, ultrahigh-temperature instantaneous sterilization and sterile filling. The method ensures the fine taste, stability and safety of the product. The plant milk is rich in strontium element and high-quality plant protein, does not contain lactose and cholesterol, and has the advantages of bone health maintenance, low sensitivity and the like. The problems that casein allergy and lactose intolerance risks exist in traditional animal milk, and existing plant milk is low in protein content, unbalanced in nutrition, dependent on additives and single in function are solved.

The invention discloses an intelligent patient safety risk reminding method and system based on PACS and RIS, and the method comprises the steps: collecting the multi-source medical data of HIS, EMR, LIS and the like in real time through an HL7 and DICOM multi-protocol fusion technology, constructing a dynamic evaluation model covering the core risks of allergy, metal implants, infectious diseases and the like, and carrying out the native integration of a hierarchical reminding mechanism at PACS and RIS workstations. The system adopts a Bayesian network model to realize dynamic adjustment of risk levels, a differentiated reminding interface is embedded through a webpage style technology, and risk reminding of each level forcibly requires a doctor to confirm and process. And the closed-loop feedback module records the medical care operation and returns the medical care operation to a related system, and continuously optimizes the risk assessment model. The problems that an existing system is isolated in data, single in reminding function and incomplete in risk coverage are solved, the clinical risk management level is remarkably improved, and the medical accident rate is reduced.

The invention discloses an anti-wrinkle firming face cream based on camellia oleosa seed oil diglyceride and a preparation method of the anti-wrinkle firming face cream. The anti-wrinkle firming face cream is prepared from deionized water, glycerin, butanediol, sodium hyaluronate, camellia oleosa seed oil diglyceride, squalane, simmondsia chinensis seed oil, cetearyl glucoside, glyceryl stearate, acetyl hexapeptide-8, palmitoyl tripeptide-1, vitamin E, 1, 2, 4-trimethyl-1, 3-pentanediol and a proper amount of water. The component A is prepared from 1, 2-hexanediol, caprylyl glycol, a thickening agent and a pH regulator; in the aspect of efficacy, through the synergistic effect of the camellia oleosa seed oil diglyceride, the acetyl hexapeptide-8, the palmitoyl tripeptide-1 and the vitamin E, efficient anti-wrinkle tightening is achieved; in the aspect of skin feeling, squalane and jojoba oil are matched with a light emulsifying system and trace xanthan gum, so that velvet matte texture is made, and the velvet is soft, smooth and not sticky; in the aspect of safety, 1, 2-hexanediol and caprylyl glycol which are safe and free of sensitization are used for corrosion prevention, no irritating component is generated, the anti-allergic skin care lotion is suitable for various skin types, the allergy risk is reduced, and reliable and comfortable skin care experience is brought to consumers.

The invention relates to an anti-canine IL-31 antibody or an antigen binding part thereof and application thereof, and belongs to the technical field of antibody preparation. The invention relates to an anti-canine interleukin-31 antibody or an antigen binding part thereof, amino acid for coding the antibody or the antigen binding part thereof, polynucleotide, a carrier containing the polynucleotide, a host cell containing the polynucleotide or the carrier, a method for preparing and purifying the antibody and application of the antibody or the antigen binding part thereof. The anti-canine IL-31 antibody disclosed by the invention can be specifically combined with a canine IL-31 antigen, and can effectively relieve symptoms such as pruritus, allergy, nasal polyp or asthma and the like. The mutated anti-canine IL-31 antibody also has a corresponding function of combining with the antigen canine IL-31, and also can be used for treating IL-31 related diseases.

Undesirable mast cell activity is associated with various diseases or conditions, such as allergy, inflammatory diseases, autoimmune diseases, and cancer. New and improved therapeutic agents that can target c-Kit and / or siglec-6 (e.g., for mast cell related diseases or disorders) still have been desired. Disclosed herein are molecules, such as antibodies and antibody fragments, capable of binding to c-Kit and / or siglec-6. Disclosed herein are molecules, such as antibodies and antibody fragments, capable of binding to c-Kit and / or siglec-6.

The invention relates to the technical field of purification, in particular to Chinese cabbage moss allergy-free factor purification equipment which comprises an outer box, one side of the outer box is communicated with a feeding pipe, a self-cleaning filtering assembly capable of automatically scraping impurities attached to different side faces is arranged in the outer box, and the self-cleaning filtering assembly comprises a filtering cylinder rotationally connected with the side wall of the outer box; one side of the filter cartridge is communicated with a transverse pipe, the transverse pipe extends to the outside of the outer box, the feeding pipe penetrates through the transverse pipe, a scraping assembly is arranged in the filter cartridge, the scraping assembly is dragged to rise when the filter cartridge rotates and then slides down to conduct scraping, a driving assembly used for driving the transverse pipe and the filter cartridge to rotate is arranged on the outer box, and the scraping assembly comprises an arc-shaped plate in sliding connection with the inner wall of the filter cartridge; and a plurality of sliding plates are fixedly connected between the two arc-shaped plates. The technical problems that particles in Chinese cabbage moss juice of existing purification equipment are prone to blocking a filter screen, the amount of blocked Chinese cabbage moss particles is large, the cleaning difficulty is increased, and the process of cleaning the filter screen is time-consuming and labor-consuming are solved.

An automated food recognition platform comprises a memory, processor, and various submodules, utilizing artificial intelligence to analyze digital media (images, photos, audiovisual) for food identification and attributes. It includes an edible food database and recipe submodule, generating personalized recipes considering dietary preferences. The automated food recognition platform also features allergy and drug interaction submodules, informing users of relevant information. A marketplace submodule tracks inventory levels, enhancing recipe recommendations. Leftover identification and meal planning submodules offer creative cooking solutions. An interactive submodule fosters a chef-user community, incorporating user feedback and social media data to refine recipe recommendations. Chefs receive compensation based on a chef rating, determined by user interactions. The platform promotes chef recipes through paid advertising services within the interactive submodule.

A method for improving gut microbiota population in a subject by administering a composition comprising allulose, erythritol or a combination thereof. A method for increasing one or more colonic bacterial populations from the families Lachnospiraceae or Eubacteriaceae by administering a composition comprising allulose, erythritol or a combination thereof. A method for preventing, treating or ameliorating a disease in a subject by administering a composition comprising allulose, erythritol or a combination thereof. The disease may be one or more of metabolic syndrome, obesity, type 2 diabetes, insulin resistance, hyperlipoproteinemia, hyperuricemia, hepatic steatosis, hypercholesterolemia, hypertriglyceridemia, irritable bowel syndrome (IBS), colon cancer, allergy, non-alcoholic fatty liver disease, inflammatory bowel disease, cardiovascular disease, or inflammation. The bacterial population may be the species Anaerostipes hadrus, Blautia obeum, Anaerobutyricum hallii, Eubacterium rectale (Agathobacter rectalis), Eubacterium callanderi, Eubacterium limosum and Eubacterium maltosivorans. A composition comprising allulose, erythritol or a combination thereof and one or more colonic bacterial populations from the families Lachnospiraceae or Eubacteriaceae is also provided. The composition may in the form of a food composition.

A yeast cell for use in the treatment and / or alleviation of allergy and / or symptoms caused by allergy, wherein the yeast cell has been treated with electromagnetic waves in the range of 1 GHz to 300 GHz, or said yeast cell has been grown from a yeast cell treated with electromagnetic waves in the range of 1 GHz to 300 GHz, and composition comprising such a yeast cell.

The invention relates to the field of medicines, and provides a tevirimat composition as well as a preparation method and application thereof. The composition contains tevirimat serving as an active component, cyclodextrin serving as an inclusion agent, meglumine serving as a solubilizer and an alkaline additive in a weight ratio of 1: (15-30): (0.05-0.2): (0.1-0.2). Wherein the solubility of the active ingredient tevirimat can be greatly improved through the matching and combined use of the three auxiliary materials including the inclusion agent, the solubilizer and the alkaline additive. Compared with the prior art, the dosage of each auxiliary material in the composition can meet the specified limit in related laws and regulations, the allergy risk, the hemolysis risk and the stimulation risk are low, and the preparation safety is better. The composition provided by the invention is simple and feasible in preparation method, more stable in preparation finished product quality and more convenient to apply. The composition can be used for treating or preventing virus infection and related diseases caused by orthopoxvirus.