The present disclosure describes a Pseudococcus preparation and a preparation method and application thereof, the Pseudococcus preparation comprises an
active ingredient, the
active ingredient comprises a specific pro-inflammatory regression
mediator (SPMs) and a pro-inflammatory regression
mediator (PRMs), the specific proinflammatory regression medium and the proinflammatory regression medium are generated by catalyzing
unsaturated fatty acid synthesized by
micrococcus by own
enzyme. According to the invention, the invention can provide the
micrococcus preparation containing the specific proinflammatory regression medium and the proinflammatory regression medium as well as the preparation method and the application of the
micrococcus preparation.