2024results about How to "Promote activation" patented technology

Methods, systems and graphical user interfaces that facilitate activation of mobile devices, such as communication devices or multi-function devices, via computers are disclosed. According to one embodiment, activation of a mobile device with respect to a wireless service provider can be performed by users through use of a computer (e.g., personal computer) that communicate with a remotely located activation server. According to another embodiment, graphical user interfaces can be presented to users so as to enable end users to easily activate mobile devices.

The present invention relates to a simple method for generating antibody-based structures suitable for in vivo use. In particular, the invention relates to a method for the generation of antibody-based structures suitable for in vivo use comprising the steps of: (a) selecting an antibody single variable domain having an epitope binding specificity; and (b) attaching the single domain of step (a) to an effector group. Uses of molecules generated using the method of the Invention are also described.

Methods, systems and graphical user interfaces that facilitate activation of mobile devices, such as communication devices or multi-function devices, via computers are disclosed. According to one embodiment, activation of a mobile device with respect to a wireless service provider can be performed by users through use of a computer (e.g., personal computer) that communicate with a remotely located activation server. According to another embodiment, graphical user interfaces can be presented to users so as to enable end users to easily activate mobile devices.

A light emitting toothbrush is provided that includes three light emitting diodes, each having a different primary color. A battery is provided as a power source, and a control circuit is used to control the diodes. The control circuit is configured to sequentially or simultaneously power some or all of the diodes, and it can be configured to vary the power to each diode, thereby providing an almost infinite spectrum of colors of light. A switch is actuated when the brush head contacts an operator's teeth, thereby activating the diodes. A package is provided that allows a potential purchaser to apply a force to the brush head and activate the lights while the toothbrush is still in the package. The control circuit can be configured to control the diodes to provide signals to the operator and / or provide aesthetically pleasing light.

A system and method for cash based purchasing using electronic commerce channels such as mobile telephone networks. Customers use cash to purchase goods and services by using a vendor's point of sale device such as a mobile telephone. A server side mobile wallet provides secure storage of user identity and profiles and a payment mechanism for users to obtain goods and services from a point of sale device. Service providers or suppliers pay a commission to point of sale vendors for use of the vendor's account and point of sale device to perform transactions for customers. A platform is provided for establishment and use of hierarchal vendor network over a number of different mobile channels.

It has been discovered that the stimulation of beta-adrenergic receptors, which activate cAMP formation, give rise to increased APP and GFAP synthesis in astrocytes. Hence, the in vitro or in vivo exposure of neuronal cells to certain compositions comprising beta-adrenergic receptor ligands or agonists, including, e.g., norepinephrine, isoproterenol and the like, increases APP mRNA transcription and consequent APP overproduction. These increases are blocked by beta-adrenergic receptor antagonists, such as propranolol. The in vitro or in vivo treatment of these cells with 8Br-cAMP, prostaglandin E2 (PG E2), forskolin, and nicotine ditartrate also increased APP synthesis, including an increase in mRNA and holoprotein levels, as well as an increase in the expression of glial fibrillary acidic protein (GFAP). Compositions and methods are disclosed of regulating APP overexpression and mediating reactive astrogliosis through cAMP signaling or the activation of beta-adrenergic receptors. It has further been found that the increase in APP synthesis caused by 8Br-cAMP, PG E2, forskolin, or nicotine ditartrate is inhibited by immunosuppressants or anti-inflammatory agents, such as cyclosporin A, and FK-506 (tacrolimus), as well as ion-channel modulators, including ion chelating agents such as EGTA, or calcium / calmodulin kinase inhibitors, such as KN93. The present invention has broad implications in the alleviation, treatment, or prevention of neurological disorders and neurodegenerative diseases, including Alzheimer's Disease.

A programmable intelligent activation module to intelligently allow access to GPS resources is provided. In accordance with pre-programmed settings, an intelligent activation module will control the frequency by which a GPS module is allowed to access a GPS or GSM network in order to acquire location information of a mobile device equipped with GPS equipment. By controlling access to a GPS or GSM network, network resources such as bandwidth are conserved unless actually needed as is determined by the intelligent activation module. Similarly, battery resources for the mobile device are also conserved in that unnecessary activation of the GPS module is prevented until such activation is actually needed. The intelligent activation module can be programmed with a variety of settings including speed, map deltas, final destination information, or settings as pre-determined by a user of the mobile device.

Semiconductor devices and methods for fabricating semiconductor devices are provided. One exemplary method comprises providing a silicon-comprising substrate having a first surface, etching a recess into the first surface, the recess having a side surface and a bottom surface, implanting carbon ions into the side surface and the bottom surface, and forming an impurity-doped, silicon-comprising region overlying the side surface and the bottom surface.

An interface is provided for a device having a touch screen such as a smart phone or tablet computer that extends the touch screen input to areas outside the touch screen area. The interface has a housing which attaches to the device. One or more input controls are mounted on the housing. The controls can be joysticks, buttons, touch pads, levers, triggers, keyboards, etc. Conductive pads are connected to the housing and and capacitively interact with the touch screen. The interface contains circuitry that transmits an electrical or capacitive signal from the user's manipulation of the controls to the conductive pads in order to activate selected areas of the touch screen. The housing may be made in multiple pieces to connect to different sides of the touch screen device.

The p21 gene encodes a cyclin dependent kinase inhibitor which affects cell cycle progression, but the role of this gene product in altering tumor growth has not been established. The present inventors have now discovered that the growth of malignant cells in vivo is inhibited by expression of p21. Expression of p21 resulted in an accumulation of cells in G0 / G1, alteration in morphology, and cell differentiation.

A therapeutic dispenser is provided that includes a housing and a carriage movably supported by the housing and including an engagement surface at a distal end thereof. A plunger is supported by the carriage and engageable with the housing to dispense a first therapeutic through the engagement surface. A second therapeutic is supported with the housing. The first therapeutic and the second therapeutic are individually dispensable from the housing. The housing may include a channel that guides movement of the carriage. The housing can include a handle and a cap. The cap is releasably engageable with the handle.

An improved hearing aid, and processes for adaptively processing signals therein to improve the perception of desired sounds by a user thereof. In one broad aspect, the present invention relates to a process in which one or more signal processing methods are applied to frequency band signals derived from an input digital signal. The level of each frequency band signal is computed and compared to at least one plurality of threshold values to determine which signal processing schemes are to be applied. In one embodiment of the invention, each plurality of threshold values to which levels of the frequency band signals are compared, is derived from a speech-shaped spectrum. Additional measures such as amplitude modulation or a signal index may also be employed and compared to corresponding threshold values in the determination.

It has been discovered that the stimulation of beta -adrenergic receptors, which activate cAMP formation, give rise to increased APP and GFAP synthesis in astrocytes. Hence, the in vitro or in vivo exposure of neuronal cells to certain compositions comprising beta -adrenergic receptor ligands or agonists, including, e.g., norepinephrine, isoproterenol and the like, increases APP mRNA transcription and consequent APP overproduction. These increases are blocked by beta -adrenergic receptor antagonists, such as propranolol. The in vitro or in vivo treatment of these cells with 8Br-cAMP, prostaglandin E2 (PG E2), forskolin, and nicotine ditartrate also increased APP synthesis, including an increase in mRNA and holoprotein levels, as well as an increase in the expression of glial fibrillary acidic protein (GFAP). Compositions and methods are disclosed of regulating APP overexpression and mediating reactive astrogliosis through cAMP signaling or the activation of beta -adrenergic receptors. It has further been found that the increase in APP synthesis caused by 8Br-cAMP, PG E2, forskolin, or nicotine ditartrate is inhibited by immunosuppressants or anti-inflammatory agents, such as cyclosporin A, and FK-506 (tacrolimus), as well as ion-channel modulators, including ion chelating agents such as EGTA, or calcium / calmodulin kinase inhibitors, such as KN93. The present invention has broad implications in the alleviation, treatment, or prevention of neurological disorders and neurodegenerative diseases, including Alzheimer's Disease.

A therapeutic dispenser is provided that includes a housing and a carriage movably supported by the housing and including an engagement surface at a distal end thereof. A plunger is supported by the carriage and engageable with the housing to dispense a first therapeutic through the engagement surface. A second therapeutic is supported with the housing. The first therapeutic and the second therapeutic are individually dispensable from the housing. The housing may include a channel that guides movement of the carriage. The housing can include a handle and a cap. The cap is releasably engageable with the handle.

A method for measuring the conduction velocity of a depolarization wave in a tissue employs a first satellite located within the tissue and a second that satellite is located within the tissue a distance away from the first satellite, e.g., by using the time of depolarization wave as reported from each satellite and the distance to determine velocity of the wave. Also provided are systems and kits that find use in accordance with the invention.

Pharmaceutical compositions and methods for using are provided for restoring β-cell mass and function in a mammal in need thereof. The pharmaceutical compositions have a biological response modifier and a β-cell growth factor in admixture with a pharmaceutically acceptable carrier, adjuvant or vehicle.

A system and method that provides remoting services in a distributed object system is provided. The system includes a remote object monitor and a remote object manipulator. The remote object monitor can provide a human readable reference to a remote object, where the human readable reference is a URL (Uniform Resource Locator) and can include protocol information, protocol data, an application name and an object URI (Uniform Resource Identifier). The remote object monitor can also provide metadata concerning a remote object, where the metadata can include information concerning interfaces implemented by a remote object, the type of a remote object, the class hierarchy of a remote object, methods implemented by a remote object, properties implemented by a remote object and attributes implemented by a remote object. The remote object monitor can also provide entry points and code interception for custom attribute based activation processing that can be performed before, after and / or substantially in parallel with non-attribute code associated with a remote object. The remote object monitor can also monitor and / or control the lifetime of a remote object, using, for example, a lease manager. The remote object manipulator can also update metadata concerning a remote object and can control the lifetime of a remote object via a lease manager, for example.

The invention relates to an improver for saline-alkali soil. The improver comprises a powder agent and a water agent, wherein the powder agent comprises the following components: organic matters, plant mycelium protein powder, active calcium, calcium superphosphate, aluminum sulfate, fatty alcohol polyoxyethylene ether ammonium sulfate, amino acid powder, bacillus subtilis and photosynthetic bacteria, and the water agent comprises the following components: citric acid, fulvic acid, humic acid, malic acid, maleic acid, fumaric acid, L-tartaric acid, pyrophosphoric acid, humic acid, lactic acid, oxalic acid, salicylic acid, sodium ion adsorbent, Tween-80 and water. The improver disclosed by the invention can improve the soil from multiple angles, namely soil structure, microorganism species, a chemical method and the like, obviously promote the release of iron and phosphorus in the soil, improve the soil structure, effectively reduce the content of sodium ions in the soil, reduce the pH value of the soil and restore land to a normal planting state after being used continuously for two years.

The invention discloses a magnesium-based composite hydrogen storage material comprising the following compositions by weight percent: 1.0-10.0% of Al, 1.0-5.0% of Ni, and the balance of Mg. A preparation method thereof comprising the following steps: at first, smelting block-shaped metal Mg and Al by a medium frequency induction to prepare Mg17Al12 alloy which is crushed to 300 meshes; hydrogenising Mg powder at 340 DEG C under a hydrogen atmosphere of 4.0MPa to prepare MgH2; then blending Mg17Al12, MgH2, Ni powder in accordance with contents by weight percent for ball-grinding for 60 to 100 hours under an atmosphere of argon. The magnesium-based composite hydrogen storage material can reversely absorb and release hydrogen at low temperature, and has high hydrogen storage capacity, excellent activation performance and superior hydrogen absorbing and releasing kinetics property. The magnesium-based composite hydrogen storage material can be used for manufacturing hydrogen source to facilitate purification and storage and transportation of hydrogen, and can also used for hydrogen storage material for fuel cells.

A Rankine cycle system includes a first Rankine cycle (2A) operated by a first working medium and a second Rankine cycle (2B) operated by a second working medium. The first Rankine cycle (2A) is constituted from an evaporator (3A), an expander (4), a condenser (5A) and a supply pump (6A), and the second Rankine cycle (2B) is constituted from an evaporator (3B), the expander (4), a condenser (5B) and a supply pump (6c). The evaporator (3A) in the first Rankine cycle (2A) and the evaporator (3B) in the second Rankine cycle (2B) are disposed at locations upstream and downstream of an exhaust emission control device (8) mounted in an exhaust passage (7) for the internal combustion engine (1). The first working medium has a boiling point higher than that of the second working medium, and the capacity of the pump (6A) in at least the first Rankine cycle (2A) is variable. Thus, the efficiency of recovery of a waste heat from the internal combustion engine by the Rankine cycle system can be enhanced to the maximum, and the activation of the exhaust emission control device can be promoted.

A dental whitening apparatus is provided that includes a body having a heating element and a light emitting device. The heating element and the light emitting device are disposed for activating a bleaching composition. A mouthpiece is connected with the body. The mouthpiece includes a dental receiving area that is formed of a material that facilitates transmission and emittance of light, and is contoured to a set of teeth. The dental receiving area has a first wall and a second wall that define a cavity. The cavity is configured for disposal of the bleaching composition. Methods of use are also disclosed.

The subject matter described herein relates to methods and systems for communicating digital greeting and informational content using a near field communication (NFC) devices, the content herein are of digital media type representing text, audio, video, image, and document formats. In one of the embodiments, unique programmed NFC stickers can be used conjunction with NFC enabled devices, such as a Smart Phone, to upload a personalized video or audio greeting on Central Server, doing so the sender activates the NFC sticker for distribution, when distributed, the recipient can tap on the same sticker and play the greeting message using the Smart Phone. In another embodiment, retail consumers can tap on NFC tags or sticker with Smart Phone to view product informational content that has been hosted on the Central Server by retailers and manufactures or by any organization that has similar needs.

A safety sensing and / or release system for a closed compartment of a vehicle is operable to detect an occupant within the vehicle compartment. The system may be operable to sense ambient conditions in the vehicle compartment, and may generate a control signal in response to the sensed conditions. The system may actuate indicators to notify operators of the vehicle that there is a person or animal detected in the compartment. Optionally, the system may open the vehicle compartment in response to a detection of an occupant and the sensed conditions. The safety system includes a false trigger protection means that limits or reduces false detections of a person or animal within the compartment.

An applicator having a substantially hollow body for accommodating an ampoule of solution. The hollow body comprises an open proximal end for receiving the ampoule and an open distal end having a flange to accept an applicator pad for applying the solution. A back plug having a lever mechanism is inserted into the open proximal end of the applicator to activate the applicator and seal the applicator after activation. Advancement of the back plug lever mechanism into the hollow body pivots the body of the ampoule to break the neck, activatiug the applicator. The back plug seals the proximal end after activation of the applicator.

A system and method for cardiac resynchronization therapy in which pacing control parameters are automatically adjusted by comparison of local electrograms acquired by a cardiac implantable electrical device with a model of cardiac electrical activity derived from surface-lead electrocardiograph measurements under baseline and paced conditions is provided. The adjusted pacing control parameters guarantee substantially maximum evidence of ventricular activation wavefront fusion while reducing the risk of compromising diastolic function. Atrioventricular intervals (AVIs] are measured and utilized to constrain the adjustment of pacing control parameters such that diastolic dysfunctions are not induced in the patient's heart.

The field of the present invention relates to genetically engineered fusion molecules, methods of making said fusion molecules, and uses thereof in anti-tumor immunotherapies. More specifically, the present invention relates to engineered fusion molecules consisting of a tumor targeting moiety fused with one or more costimulatory molecules / chemokines / cytokines.

It has been discovered that the stimulation of beta-adrenergic receptors, which activate cAMP formation, give rise to increased APP and GFAP synthesis in astrocytes. Hence, the in vitro or in vivo exposure of neuronal cells to certain compositions comprising beta-adrenergic receptor ligands or agonists, including, e.g., norepinephrine, isoproterenol and the like, increases APP mRNA transcription and consequent APP overproduction. These increases are blocked by beta-adrenergic receptor antagonists, such as propranolol. The in vitro or in vivo treatment of these cells with 8Br-cAMP, prostaglandin E2 (PG E2), forskolin, and nicotine ditartrate also increased APP synthesis, including an increase in mRNA and holoprotein levels, as well as an increase in the expression of glial fibrillary acidic protein (GFAP). Compositions and methods are disclosed of regulating APP overexpression and mediating reactive astrogliosis through cAMP signaling or the activation of beta-adrenergic receptors. It has further been found that the increase in APP synthesis caused by 8Br-cAMP, PG E2, or forskolin is inhibited by immunosuppressants, immunophilin ligands, or anti-inflammatory agents, such as cyclosporin A, and FK-506 (tacrolimus), as well as ion-channel modulators, including ion chelating agents such as EGTA, or calcium / calmodulin kinase inhibitors, such as KN93. The present invention has broad implications in the alleviation, treatment, or prevention of neurological disorders and neurodegenerative diseases, including Alzheimer's Disease.