10results about How to "Promote activation" patented technology

The application discloses an LDH-based vaccine adjuvant and a preparation method and application thereof, and belongs to the technical field of aluminum adjuvant preparation of vaccines, and the preparation method comprises the following steps: mixing at least one of soluble magnesium salt, soluble zinc salt, soluble manganese salt and soluble calcium salt with soluble aluminum salt, and then performing a co-precipitation reaction with a sodium hydroxide aqueous solution in a colloid mill device, and performing crystallization to obtain LDH nanosheets; dispersing the LDH nanosheets in a PBS solution, adding a hepatitis B surface antigen molecule drug, uniformly mixing, and then performing centrifugation to obtain the LDH-based vaccine adjuvant. The LDH-based vaccine adjuvant can significantly promote the maturation of DC cells and the activation of T cells, and the total IgG level reflects the overall humoral immune response intensity of the body to vaccines or pathogens; the LDH-based vaccine adjuvant forms a "storage library" at an injection site to store antigens and slowly release the antigens, and the purpose of long-time continuous stimulation of the immune system in the body is achieved.

This invention belongs to the field of metal material corrosion protection technology, specifically relating to a highly active aluminum alloy sacrificial anode for full ocean depth and its preparation method. The sacrificial anode uses Al as the main raw material, with added alloying elements: Zn, In, Ga, Mg, Ti, Ca, and Mn. The preparation method involves first heating Al and Zn to 750–1000℃, then adding In, Ga, Mg, Ti, Ca, and Mn, and finally casting at a temperature of 700–750℃. By adding Ca, an octet aluminum alloy sacrificial anode for full ocean depth is formed. The activation ability is improved by the dissolution and redeposition of In and Ga, the disruption of the continuity and density of the oxide layer by Zn and Mg, and the activation of the Al matrix surface by micron-level dot pairs. At the same time, Ti refines the grain size, resulting in a uniform and segregated distribution of alloying elements, avoiding internal self-corrosion, and improving current efficiency. It can be applied to full ocean depth environments from 0 to 10000 meters, with a current efficiency of 90–95%.

This invention provides a functional fascia gun head, belonging to the field of massage devices and physical therapy technology. This functional fascia gun head consists of a power-generating layer and a regular fascia gun head; the power-generating layer can be placed outside or inside the regular fascia gun head. Another design of the functional fascia gun head is entirely composed of a power-generating layer. When the fascia gun is in operation, the power-generating layer generates a Maxwell pulse electric field and a pulse displacement field current under force, forming a pulse wave. This pulse wave can effectively penetrate multiple layers of skin structure, promoting blood circulation and cell activation, achieving various health benefits such as warming the meridians and activating collaterals, relaxing muscles, relieving pain, preventing injury, dispelling cold and dampness, harmonizing yin and yang, promoting homeostasis, and delaying aging. The power-generating layer is made of various materials and has various structural forms; the manufacturing process is simple, significantly improving the product's multifunctionality and ease of use, providing more diversified and efficient options for the medical and beauty fields.

The present application discloses a supported bimetallic-based two-dimensional nanocatalytic material, a preparation method thereof, and an application thereof, which relate to the technical field of catalysts. The preparation method includes: preparing a plasma nanosheet with a single-layer structure or a few-layer structure; dispersing the plasma nanosheet in a solvent and adding a copper source to prepare a first mixed solution; subjecting the first mixed solution to stirring treatment in an inert gas environment, and successively performing freeze-drying treatment and calcination treatment in a hydrogen atmosphere to prepare a nanosheet-Cu; successively adding HAuCl4 and HCl to the nanosheet-Cu, mixing and reacting under a preset light condition to prepare a supported bimetallic-based two-dimensional nanocatalytic material, namely, a nanosheet-Cu-Au. The present application can achieve the functional division and spatial synergy of bimetallic active sites, and promote the efficient generation, separation, and directional transport of photo-generated carriers, thereby improving the reaction efficiency and product selectivity of the co-reduction of nitrate and carbon dioxide to urea.

This application discloses the use of USP15 inhibitors in the preparation of medicaments for the treatment and / or prevention of renal cell carcinoma, as well as pharmaceutical compositions and kits thereof.

This invention discloses a membrane coupling-based system and method for treating copper complex wastewater. The method includes: S1 pre-oxidation and complex-breaking treatment; S2 adding a heavy collector to the wastewater and performing cross-flow filtration using a membrane separation device equipped with an electrochemically activated membrane module to obtain a concentrated solution of the heavy collector-copper complex; S3 adjusting the pH of the concentrated solution and performing secondary filtration using the same membrane separation device, retaining the heavy collector for reuse, with the permeate being an acidic solution containing free copper ions; S4 chemically depositing and separating the acidic copper-containing solution to recover copper. In the S2 enrichment stage, a reducing electric field is applied using the membrane as the cathode, and in the backwashing stage, an oxidizing electric field is applied as the anode. The heavy collector is a graft copolymer or terpolymer of polyacrylic acid and β-cyclodextrin, which forms a loose, porous gel layer on the membrane surface during enrichment and naturally peels off. This invention achieves efficient complex breaking of copper complexes, high-purity recovery of copper resources, recycling of the heavy collector, and effective control of membrane fouling.

This invention discloses an injectable photocurable hydrogel with anti-inflammatory and pro-angiogenic tissue regeneration properties, belonging to the field of biomedical materials technology. The hydrogel is a methacrylic anhydride-modified gelatin hydrogel loaded with calcium phosphate oligomers and sulfur quantum dots. Its preparation method involves dissolving methacrylic anhydride-modified gelatin in a phosphate buffer solution, then adding calcium phosphate oligomers and sulfur quantum dots, followed by adding a photoinitiator and mixing thoroughly. Finally, it is cured under ultraviolet or blue light irradiation. This invention also discloses the application of the injectable photocurable hydrogel with anti-inflammatory and pro-angiogenic tissue regeneration properties in the preparation of products for treating infected bone defects. This hydrogel can release the bioactive components of sulfur quantum dots and calcium phosphate oligomers in situ, synergistically promoting the healing of infected bone defects through multiple effects including antibacterial, immunomodulatory, angiogenesis, and osteoproliferative effects.

The application discloses an energy-saving process for activating biochar by wood vinegar steam through a thermo-chemical-physical coupling method, wherein wood vinegar steam is used as an activating agent instead of water vapor, and wood vinegar liquid is recycled in the process, serving as a heat carrier and participating in a thermo-chemical reaction to release heat, so that energy is saved and emission is reduced, and the process is a green new process, energy saving over 60%, wood vinegar liquid utilization rate 100%, and no waste liquid discharged. Due to the ionization of acetic acid, a characteristic component, the process also meets the swelling action principle of acid activation, so that biochar is more easily activated, and has double effects, and is a thermo-chemical-physical coupling method. The wood vinegar liquid generated in the biochar process is used as an activating agent, so that the problems of high energy consumption of a single water vapor activation method and chemical pollution of a single phosphoric acid activation method are avoided. The process overcomes the shortcomings of traditional methods, saves energy and reduces emission, reduces production cost, and effectively realizes comprehensive utilization of wood vinegar liquid.

The utility model belongs to vulcanized isobutene production equipment technical field, specifically disclose a high sulfur content vulcanized isobutene production device, including from top to bottom once series' sulfur adding kettle, heat exchanger, vulcanization kettle, sulfur adding kettle top fixedly connected with solid pipe and liquid adding pipe, the first stirrer is rotatably connected in sulfur adding kettle, a plurality of electric heating rods are fixedly connected in sulfur adding kettle, sulfur adding kettle bottom is passed through first connecting pipe and is communicated with heat exchanger, and the heat exchanger is communicated with vulcanization kettle through second connecting pipe, a plurality of air pipes are fixedly connected in vulcanization kettle, a plurality of air nozzles are connected on air pipe, and air pipe is communicated with air inlet pipe that penetrates vulcanization kettle side wall, and the second stirrer is rotatably connected in vulcanization kettle. The utility model sets up sulfur adding kettle, and sets up electric heating rod in sulfur adding kettle, can utilize high temperature and promote the activation of sulfur, avoid the production of mercaptan of elemental sulfur and olefin, thereby reduce the generation of harmful gas.

This invention provides novel formulations for promoting cell recycling and methods for increasing the responses of various genes related to cell recycling. It also includes degradation system promoters for promoting recycling, containing water-soluble nucleoproteins, particularly low molecular weight compounds (250 to 15000) obtained through enzymatic treatment of fish sclerotium; health foods containing these degradation system promoters; and methods for increasing the responses of various degradation system-related genes and promoting cell recycling through oral intake of these degradation system promoters.