One of the tasks of the invention is to define an effective part for using cotinus coggygria, and provide pharmacodynamics usages of the effective part and various preparations. The new usage of the effective part of the cotinus coggygria is that the leaves, stems, branches and roots of the cotinus coggygria are collected to extract general flavone as a drug which can improve animal organism hypoxia tolerance or thrombolysis, etc. The invention has the advantages that the effective part of the cotinus coggygria is defined, and the effective components are separated for medical use, thus obviously improving the therapeutic effect. Experiments prove that the preparation of the invention can obviously improve animal hypoxia tolerance and the effect thereof is equal to a western medicine antianginal drug Propranolol, thus avoiding the toxic side effect of the western medicine and having the actions of improving blood circulation and reducing whole blood viscosity. Therefore, the preparation can be applicable for preventing and curing coronary heart disease, angina pectoris, miocardial infarction, as well as obstruction of Qi in chest, dizziness, brachypnea, palpitation, chest distress or thoracodynia caused by internal resistance of congestion. Meanwhile, the preparation of the invention also has the actions of anticoagulation in vitro and thrombus dissolving.