355results about How to "Reduce rate" patented technology

This invention is directed to devices and methods for assessing a patient. The devices have at least one impedance measuring element functionally connected to a programmable element, programmed to analyze an impedance measurement, and to provide an assessment of at least one respiratory parameter of the patient. Preferably the device includes electronics which aid in calibration, signal acquisition, conditioning, and filtering.

Novel polypeptide derivatives having protracted profile of action. The present invention relates to a compound which comprises a therapeutic polypeptide linked to an albumin binding residue via a hydrophilic spacer. The present invention also relates to a compound which comprises a therapeutic polypeptide linked to an albumin binding residue via a hydrophilic spacer that separates the polypeptide and the albumin binding residue with a chemical moiety comprising at least 5 non-hydrogen atoms where 30-50% of these atoms are either N or O. In one embodiment of this invention the spacer is defined as —(CH₂)_lD[(CH₂)_nE]_m(CH₂)_pQ_q-, wherein l, m and n independently are 1-20 and p is 0-10, Q is -Z-(CH₂)_lD[(CH₂)_nG]_m(CH₂)_p—, q is an integer in the range from 0 to 5, each D, E and G independently are selected from —O—, NR³—, —N(COR⁴)—, —PR⁵(O)—, and —P(OR⁶)(O)—, wherein R³, R⁴, R⁵, and R⁶ independently represent hydrogen or C_1-6-alky, Z is selected from —C(O)NH—, —C(O)NHCH₂—, —OC(O)NH—, —C(O)NHCH₂CH₂—, —C(O)CH₂—, —C(O)CH═CH—, —(CH₂)_s—, —C(O)—, —C(O)O— or —NHC(O)—, wherein s is 0 or 1.

A method of noise suppression to suppress noise in a signal containing background noise (314) in a communications path between a cellular communications network and a mobile terminal. The method comprises the steps of:

• • estimating and up-dating a spectrum of the background noise (332, 334); using the background noise spectrum to suppress noise in the signal; generating an indication to indicate the operation of at least one of a discontinuous transmission unit (DTX) and a bad frame handling unit (BFI); and freezing estimating and up-dating of the spectrum of the background noise when the indication is present.

To provide a method for producing chemically tempered glass, whereby frequency of replacement of the molten salt can be reduced. A method for producing chemically tempered glass, which comprises repeating ion exchange treatment of immersing glass in a molten salt, wherein the glass comprises, as represented by mole percentage, from 61 to 77% of SiO₂, from 1 to 18% of Al₂O₃, from 3 to 15% of MgO, from 0 to 5% of CaO, from 0 to 4% of ZrO₂, from 8 to 18% of Na₂O and from 0 to 6% of K₂O; SiO₂+Al₂O₃ is from 65 to 85%; MgO+CaO is from 3 to 15%; and R calculated by the following formula by using contents of the respective components, is at least 0.66:

R=0.029×SiO₂+0.021×Al₂O₃+0.016×MgO−0.004×CaO+0.016×ZrO₂+0.029×Na₂O+0×K₂O−2.002

The invention describes compounds, compositions and methods of using the same comprising a chemical moiety covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.

Described are osteogenic paste compositions with enhanced osteoinductive properties for use in bone repair. Compositions comprising a quickly resorbable paste carrier, a more slowly resorbed mineral matrix, and Bone Morphogenetic Protein (BMP) or other osteogenic factor are described which enable increased osteoinductive activity while retaining a reliable scaffold for the formation of new bone at the implant site. Methods for making and methods for therapeutic use of the compositions are also disclosed.

The present invention relates to materials and methods for the in vivo transport and deliver of nucleic acids. More particularly, it concerns the use of lipoproteins, including but not limited to, low density lipoproteins ("LDL"), and/or apolipoproteins for the binding and in vivo transport of nucleic acids. In addition, the present invention relates to the use of lipoproteins in the early detection of cancer and/or metastatic cancer and/or arteriosclerosis.

A method and apparatus optimizes the protection of computing networks. This protection utilizes attenuated (weakened) strains of live, replicating, malicious code such as viruses and worms, analogous to the development of live, attenuated, human vaccines in the medical field. In a preferred embodiment, this is achieved by (1) attenuating a malicious program, e.g. a virus or worm, or software vulnerability by limiting its virulence, i.e., limiting its damage and resource usage, (2) modifying the virus to confer immunity on the network that it infects, e.g., automatically patching a vulnerability, or marking the infected host as immune to further infection, (3) releasing the newly attenuated virus into the network, (4) tracking the attenuated virus and its success rate (e.g., rate and ratio of successfully patched to un-patched vulnerable hosts), and (5) limiting the spread of the virus vaccine, e.g., emergency termination, timeout to die, “white-list” of hosts not to touch, network IP address limitation, restricted IP ranges, variable address selection algorithm.

The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. In some embodiments, the 5′ nuclease activity of a variety of enzymes is used to cleave a target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

We have developed a method of PECVD depositing a-SiN_x:H films which are useful in a TFT device as gate dielectric and passivation layers, when a series of TFT devices are arrayed over a substrate having a surface area larger than about 1 m², which may be in the range of about 4.1 m², and even as large as 9 m². The a-SiN_x:H films provide a uniformity of film thickness and uniformity of film properties, including chemical composition, which are necessary over such large substrate surface areas. The films produced by the method are useful for both liquid crystal active matrix displays and for organic light emitting diode control.

A fixture comprising a light sensor and an actuator for assigning the fixture to at least one zone. A fixture comprising a light source, a motion sensor and a light sensor. A fixture comprising a motion sensor, a light sensor and a wireless transmitter (optionally also a wireless receiver). A fixture configured to detect light brightness values over a time-span, and identify a period of time with smallest average brightness. A fixture configured to dim at a first rate when a motion sensor senses no motion for a designated period of time, and optionally also configured to brighten at a second rate when the motion sensor detects motion. A fixture configured to dim to not less than a designated percentage unless motion is detected during the dimming. A lighting control system, comprising fixtures and an actuator configured to assign fixtures to zones. Also, other lighting control systems and methods.

System and method for the combination of a flywheel and motor/generator inside a wheel hub for hybrid vehicle propulsion. The flywheel and motor/generator are connected by a planetary gear system, in which a first port is connected to the flywheel, a second port is connected to the wheel hub, and a third port is connected to a motor/generator. An additional motor/generator may be used at one of the first port and second port. The system may be used in an electric-kinetic hybrid mode, or in a fuel-kinetic hybrid mode, when used in a vehicle having an internal combustion engine as the prime mover. Efficiency of energy storage and release is significantly improved in comparison to prior art.

A method of controlling a radio access network entity of a data unit communication network is described, said radio access network entity being involved in providing a transport service to a radio terminal of said data unit communication network, said transport service being characterized by a set of values associated with respective service quality parameters, said method comprising: monitoring (S30) a communication quality at the radio access level of a communication between said terminal and an access point of said radio access network, and setting (S31) a congestion indication marking in data units of said transport service if said communication quality fulfils a radio communication degradation condition.

The invention discloses methods for sending, receiving and transmitting downlink control information (DCI) and related devices. More specifically, the sending method comprises: a base station sends DCI to user equipment (UE) on N subcarriers corresponding to a subframe through a physical downlink control channel (PDCCH), wherein the N is a positive integer and the PDCCH is located at one or two slots in the subframe; when the PDCCH is located on the one slot in the subframe, a time domain termination position of the PDCCH is a last orthogonal frequency division multiplexing (OFDM) symbol of the slot; and when the PDCCH is located on the two slots in the subframe, the time domain termination position of the PDCCH is a last OFDM symbol of the subframe. According to the invention, sending, receiving and monitoring of DCI are carried out in the scene of indoor hotspot coverage of long term evolution (LTE); and moreover, transmission with low cost, rapid rate and high reliability is realized.

A wiring board includes a substrate core and a ceramic chip to be embedded therein. The substrate core has a housing opening portion opening at a core main surface. The ceramic chip is accommodated in the housing opening portion so that the core main surface and a chip first main surface face the same way. The ceramic chip includes a plurality of second terminal electrodes comprised of a metallized layer and formed on the chip second main surface so as to protrude therefrom. A projecting portion, disposed on the second main surface side so as to surround a plurality of the second terminal electrodes, is formed on the chip second main surface so as to protrude therefrom.

A liquid metal evaporation source for use in Molecular Beam Epitaxy and related metal vacuum deposition techniques. An evaporator is maintained at a high temperature to evaporate a liquid metal, a reservoir for holding the liquid metal source is maintained at a temperature above the melting point of the metal but below the temperature in the evaporator, and a hollow transport tube connecting the evaporator and reservoir is maintained at a temperature between these temperatures. The reservoir is in the shape of a hollow cylinder with a close-fitting cylindrical piston which is used to force the liquid metal through the hollow transport tube into the evaporator. The liquid metal will not flow past the piston seal if a suitably small gap is formed between the piston and the reservoir walls wherein the surface tension of the liquid metal will exceed its hydrostatic pressure against the piston thus forming a leak-tight seal.

A method and apparatus for string load reduction and real-time pitch alteration on stringed instruments. A string load is substantially reduced with a camming surface actuator so that the pitch can be rapidly manipulated by an input force which is generated by human power or an electronically controlled motor. Various types of camming surfaces are provided as well as a load optimization calculation which determines the shape of a variable ratio camming surface. Multiple embodiments are described including a constant force pitch alteration device, a motorized control system with pitch compensation and real-time tracking of string pitch to multiple relative input signals, a control signal generator based on real-time position measurement of a control object relative to an electromagnetic radiation sensor, and methods for generating mechanical looping, vibrato, and polyphonic chorus effects which can be automated or dynamically controlled by a user. Other embodiments are described and shown.

A method of chemically cleaning normally immersed suction driven filtering membranes involves backwashing a chemical cleaner through the membranes while the tank is empty in repeated pulses in which the chemical cleaner is pumped to the membranes separated by waiting periods in which chemical cleaner is not pumped to the membranes. The duration and frequency of the pulses is preferably chosen to provide an appropriate contact time of the chemical, preferably without allowing the membranes to dry between pulses and without using excessive amounts of chemical. In other aspects, such membranes preferably used for filtering water to produce potable water in a batch process are backwashed with a chemical cleaner substantially at the same time as the tank is being drained. The chemical cleaner is optionally supplied in pulses. In other aspects, chemical cleaner backwashes are started before the membranes foul significantly and are repeated at least once per week to reduce the rate of decline in the permeability of the membranes so that intensive recovery cleaning is required less frequently. When performed in situ, each cleaning event comprises (a) stopping permeation and any agitation of the membranes, (b) backwashing the membranes with a chemical cleaner in repeated pulses and (c) resuming agitation, if any, and permeation. The pulses last for between 10 seconds and 100 seconds and there is a time between pulses between 50 seconds and 6 minutes. Each cleaning event typically involves between 5 and 20 pulses.

In a flush memory system according to the present invention, a merge control section (3f) reads data on an enabled page from a predetermined physical block using a read section (3b), and writes the data onto a blank page using a write section (3c), thereby copying the data on the enabled page onto the blank page. Then, the merge control section disables the source, enabled page using a page-disabling section (3e). When finishing the copying of data on all the enabled pages in the predetermined physical block, the merge control section collectively erases all the data in the physical block using an erase section (3d).

A transmitting apparatus, a receiving apparatus and a wireless communication method for suppressing interference between codes, while further reducing the ratio of redundant components occupying a signal to improve the transmission efficiency. The transmitting apparatus (100) transmits a signal having a frame structure in which a plurality of symbols follow a pilot symbol to which a guard interval has been added. In the receiving apparatus (200) that receives that signal, a long FFT target section acquiring part (202) acquires, from the received OFDM signal, a long FFT target section that is a target section in which delay waves are to be removed by use of a pilot symbol. A long FFT part (203) performs a fast Fourier transformation of the long FFT target section to convert it to a frequency domain signal. A frequency equalizing part (204) performs a frequency equalization of the long FFT target section by use of an interpolation result of communication line estimation value. A long IFFT part (205) performs an inverse fast Fourier transformation of the long FFT target section as frequency equalized to convert it back to a time domain signal.

A closing device that includes a latching member that when moved a given distance utilizes a gear to effect a mechanical advantage that results in an end of a biasing member being moved less than the given distance. The biasing member is used in moving a first drawer slide member to a closed position relative to a second drawer slide member, and use of the gear and the resulting mechanical advantage provide a smoother transition when the first drawer slide member is engaged or disengaged from the closing device.

A touch sensor includes first electrodes which are driving electrodes of the touch sensor, second electrodes which are detecting electrodes of the touch sensor, third electrodes, and an insulating film which is stacked on the first electrodes. Each of the first electrodes extends in a first direction. Each of the second electrodes and each of the third electrodes are formed on the insulating film, and extend in a second direction. The second electrodes overlap with partial regions of the first electrodes, and the third electrodes overlap with other partial regions of the first electrodes and are formed in gaps between the second electrodes. A film thickness of the insulating film between the first electrodes and the third electrodes varies due to pressing force in a film thickness direction, and the insulating film constitutes the electrostatic capacitance-type pressure sensor with first electrodes and the third electrodes.

Topically absorbable compositions with bioactive or bioavailable cannabis-derived cannabinoids known to be effective for CB1 or CB2 modulation, and a plurality of indications for patients in need, and methods for producing composition, without detectable or biologically active levels of THC. Method uses a heat cycle process to combine cannabinoids with flax seed oil and at least one triglyceride, to produce an extract. The extract can include non-psychoactive agents, namely, CBD and accordingly does not deleteriously impact federal legal schemes or bone fide drug-testing regimes.

A magnetoresistive element has a magnetization pinned layer, a nonmagnetic spacer layer including a stack of a nonmagnetic metal layer, a resistance increasing layer and another nonmagnetic metal layer, a magnetization free layer having an fcc crystal structure, a cap layer having an fcc, an hcp, or a bcc crystal structure and having an interatomic distance between nearest neighbors greater than that of the magnetization free layer, and a pair of electrodes configured to provide a sense current in a direction substantially perpendicular to planes of the magnetization pinned layer, the nonmagnetic spacer layer, and the magnetization free layer.

Abuse resistant pharmaceutical formulations are provided that contain one or more abusable drugs and one or more abuse deterrent components. The abuse deterrent component(s) prevent the abusable drug(s) from being removed/extracted to an appreciable extent and/or rate. The abuse deterrent component(s) may be in the form of pellets, beads, beadlets, granules, powders, or the like, and may comprise a core that contains a material that is both hydrophilic and hydrophobic, and optionally a pH-dependent coating.

A stent (30) formed from cannula and having flexible segments (31) and high hoop strength segments (32) alternating therealong. Longitudinal struts or tie bars (41) interconnect the segments. Minimal length reduction of the strut occurs upon expansion. In the high hoop strength segment (32), struts (37) in a zig-zag configuration (Gianturco Z-stent) are initially parallel in the unexpanded strut condition. In the flexible segment (31), struts (58) extend from a respective C-shaped bend (59) to converge at the opposite ends thereof when unexpanded. In one embodiment, certain adjacent struts (39–41) of the hoop segment are spaced apart by elongated openings or gaps (46, 48) interposed therebetween and interconnected at their respective ends (42, 44) to form a T-shaped strut interconnection (45). The selected width (50, 51) of the first and third struts (54, 57) increases toward the ends (47, 48) of the elongated openings (46, 48) adjacent the strut interconnection (45). This strut width increase about one end of the strut significantly reduces the tensile strain exhibited about the opening end when the stent is radially expanded during manufacture. The tip length (52, 55) of the struts about the interconnection (45) is also adjusted (increased) along with the other C-shaped strut interconnections (59, 71) to further distribute the tensile strain developed during radial expansion.

A system for sensing an impending collision and controlling a safety device such as an airbag in response to the detection of an impending collision target. Deployment characteristics of the safety device are adjusted based on sensor output. One implementation of the system includes a radar sensor and a vision sensor carried by the vehicle. The radar sensor provides a radar output related to the range and relative velocity of the target. The vision sensor provides a vision output related to the bearing and bearing rate of the target. An electronic control module receives the radar output and the vision output and generates control signals for control safety device and adjusting deployment characteristics.

A method and apparatus for cleaning a chamber in a substrate processing system having less reactivity with the chamber walls and the components contained therein. The method includes mixing a diluent gas with a flow of radicals produced by a plasma remotely disposed with respect to the chamber, at a point located between a plasma applicator and the chamber. The apparatus includes a fluid manifold having multiple inlets and an outlet with the outlet being coupled to an intake port of the chamber. One of the inlets are in fluid communication with the plasma applicator, with the remaining inlets being in fluid communication with a supply of the diluent gas. In this fashion, the diluent gas flow and the flow of reactive radicals mix when traveling between the inlets and the outlet to form a gas-radical mixture egressing from the outlet and traversing through the intake port.

Methods and compositions for the treatment of Alzheimer's Disease are described. More specifically, the invention demonstrates that administration of cardiovascular agents to a mammal suffering from the symptoms of Alzheimer's Disease causes an amelioration of those symptoms. The finding of the present invention can be used in treatment regimens designed to attenuate or prevent Alzheimer's Disease.

A radiation-sensitive resin composition comprising an acid-labile group-containing resin obtained by living radical polymerization having a specific structure which is insoluble or scarcely soluble in alkali, but becomes alkali soluble by the action of an acid, and a photoacid generator, wherein the ratio of weight average molecular weight to number average molecular weight (weight average molecular weight/number average molecular weight) of the acid-labile group-containing resin is smaller than 1.5.