443results about How to "Reduce appearance" patented technology

The present invention is directed to novel methods of synthesizing multiple copies of a target nucleic acid sequence which are autocatalytic (i.e., able to cycle automatically without the need to modify reaction conditions such as temperature, pH, or ionic strength and using the product of one cycle in the next one). In particular, the present invention discloses a method of nucleic acid amplification which is robust and efficient, while reducing the appearance of side-products. The method uses only one primer, the “priming oligonucleotide,” a promoter oligonucleotide modified to prevent polymerase extension from its 3′-terminus and, optionally, a means for terminating a primer extension reaction, to amplify RNA or DNA molecules in vitro, while reducing or substantially eliminating the formation of side-products. The method of the present invention minimizes or substantially eliminates the emergence of side-products, thus providing a high level of specificity. Furthermore, the appearance of side-products can complicate the analysis of the amplification reaction by various molecular detection techniques. The present invention minimizes or substantially eliminates this problem, thus providing an enhanced level of sensitivity.

The present invention is directed to novel methods of synthesizing multiple copies of a target nucleic acid sequence which are autocatalytic (i.e., able to cycle automatically without the need to modify reaction conditions such as temperature, pH, or ionic strength and using the product of one cycle in the next one). In particular, the present invention discloses a method of nucleic acid amplification which is robust and efficient, while reducing the appearance of side-products. The method uses only one primer, the “priming oligonucleotide,” a promoter oligonucleotide modified to prevent polymerase extension from its 3′-terminus and, optionally, a means for terminating a primer extension reaction, to amplify RNA or DNA molecules in vitro, while reducing or substantially eliminating the formation of side-products. The method of the present invention minimizes or substantially eliminates the emergence of side-products, thus providing a high level of specificity. Furthermore, the appearance of side-products can complicate the analysis of the amplification reaction by various molecular detection techniques. The present invention minimizes or substantially eliminates this problem, thus providing an enhanced level of sensitivity.

Pharmaceutical preparations for topical or local administration of drugs directly to the skin for treatment of disorders of the subcutaneous fatty tissue, in particular in cases of cellulite, are disclosed herein. In a preferred embodiment, the drug is danazol or gastrinone. In another embodiment, the drug is danazol in combination with an aromatase inhibitor or an estrogen compound. The preferred formulations contain drugs in the form of micro or nanoparticles, which may be formed of drug alone or in combination with an excipient or carrier. The excipient or carrier may modify the release rates or enhance absorption into the affected area. The drug formulation may be in the form of a cream, lotion, ointment, gel or emulsion, solution or foam.

A device for manufacturing a three-dimensional product, which device comprises a work table on which said three-dimensional product is to be built, a powder dispenser which is arranged to lay down a thin layer of powder on the work table for the formation of a powder bed, a ray gun for giving off energy to the powder whereby fusion of the powder takes place, members for controlling of the beam released by the ray gun across said powder bed for the formation of a cross section of said three-dimensional product through fusion of parts of said powder bed, and a controlling computer in which information about successive cross sections of the three-dimensional product is stored, which cross sections build the three-dimensional product, the controlling computer intended to control said members for guiding the ray gun across the powder bed according to a running schedule forming a cross section of said three-dimensional body, whereby said three-dimensional product is formed by successive fusion of successively formed cross sections from powder layers successively laid down by the powder dispenser.

A device for manufacturing a three-dimensional product, which device comprises a work table on which said three-dimensional product is to be built, a powder dispenser which is arranged to lay down a thin layer of powder on the work table for the formation of a powder bed, a ray gun for giving off energy to the powder whereby fusion of the powder takes place, members for controlling of the beam released by the ray gun across said powder bed for the formation of a cross section of said three-dimensional product through fusion of parts of said powder bed, and a controlling computer in which information about successive cross sections of the three-dimensional product is stored, which cross sections build the three-dimensional product, the controlling computer intended to control said members for guiding the ray gun across the powder bed according to a running schedule forming a cross section of said three-dimensional body, whereby said three-dimensional product is formed by successive fusion of successively formed cross sections from powder layers successively laid down by the powder dispenser.

System and method for providing instant access to information about a vehicles insurance coverage. The linking element physically located on the vehicle body which includes vehicle license plate, or can be installed on vehicle for the specific purpose of retrieving insurance information. Linking element can be, radio frequency identification (RFID) or barcode, or quick response code (QRC) affixed anywhere on vehicle. Authorized users immediately access and retrieve current vehicle insurance coverage from a plurality of information retrieval systems including portable and fixed scanning systems, smart phone or other portable devices based on the linking element. The RFID scanner or smart phone transmit information over a communication link to a database / fileserver containing the most current vehicle insurance information associated with vehicle's vehicle identification number. The RFID reader or smart phone then receives information from the database / fileserver on the specific VIN queried where it is reviewed by an authorized user.

A topical skin care composition comprising kakadu plum extract or acai berry extract, or a combination of both, is disclosed. The composition can include a high oxygen radical absorbance capacity (ORAC) value. The composition can improve the skin's visual appearance, physiological functions, clinical properties, and / or biophysical properties.

This invention provides a leather-like sheet excellent in hand softness and appearance durability, as a composite sheet consisting of a nonwoven fabric composed of ultrafine long fibers in which ultrafine fibers with a fiber fineness of 0.0001 to 0.5 dtex are entangled with each other, and a woven or knitted fabric, characterized in that at least some of the aforementioned ultrafine fibers pass through the woven or knitted fabric, that the appearance is grade 3 or higher while the abrasion loss is 10 mg or less in the evaluation of abrasion resistance, and that the sheet is substantially composed of only a fiber material of a non-elastic polymer.

Portable objects such as luggage, cases, purses, bags, sporting equipment, weaponry and the like typically have a handle and a detachable shoulder strap. The discomfort caused by the weight of the object and the shock to both carrier and object of walking is alleviated by clipping an elastic apparatus between the ends of the shoulder strap and the portable object. Disclosed is a short elastic suspender that includes an elastic strap to be removably attached by a first connector to the D-ring of a portable object. The other end of the suspender has a D-ring connector configured to removably be attached to by the snap / hook fastener of the original shoulder-carrying strap of the portable object.

Disclosed is a color adjusting arrangement comprising: i) a first wavelength converting material arranged to receive ambient light and capable of converting ambient light of a first wavelength range into light of a second wavelength range, and / or reflecting ambient light of said second wavelength range, said second wavelength range being part of the visible light spectrum; and ii) a complementary wavelength converting material arranged to receive ambient light and capable of converting part of said ambient light into light of a complementary wavelength range, which is complementary to said second wavelength range, and arranged to allow mixing of light of said second wavelength range and said complementary wavelength range; such that light of said second wavelength range that is emitted and / or reflected by said first wavelength converting material and light of said complementary wavelength range is mixed when leaving the color adjusting arrangement towards a viewing position, the light leaving the color adjusting arrangement thereby appearing less colored, i.e. having a color point substantially near the black body line. The invention thus allows an undesirable colored appearance of a semiconductor-phosphor based light source to be at least partly extinguished or neutralized.

The invention relates to cosmetic or dermatologic compositions comprising a microsphere and a film forming component.

A comprehensive, single agent cosmetic cream or lotion containing a high number of ingredients that target anti-aging in a defined manner. The cream or lotion contains a high number and variety of active substances that demonstrate excellent safety and efficacy in all of the various defined categories of skin aging, including but not limited to wrinkles, abnormal pigment or brown spots due to aging of the skin and an unexpectedly high efficacy in the reduction of redness and acne and rosacea blemishes.

The invention features a method of (i) reducing the appearance of pores or oil on the skin and (ii) evening skin tone or smoothing skin by applying to an area of skin in need of such treatment a composition including an anti-acne agent, an antimicrobial agent, and a lactate.

PCT No. PCT / JP96 / 01126 Sec. 371 Date Dec. 30, 1996 Sec. 102(e) Date Dec. 30, 1996 PCT Filed Apr. 25, 1996 PCT Pub. No. WO96 / 35307 PCT Pub. Date Nov. 7, 1996In a mobile communication system according to this invention, an integrated control apparatus (ISa1) is arranged between a plurality of base stations (CSa1, CSa1, . . . ) arranged in an area with a low traffic density, and a public digital network (INW), the integrated control apparatus (ISa1) accommodates I' lines of the base stations (CSa1, CSa1, . . . ), the integrated control apparatus (ISa1) and the public digital network are connected via I' lines having a smaller number of channels than the total number of channels of the I' lines, and the integrated control apparatus (ISa1) performs various kinds of control for call origination / termination with the base stations (CSa1, CSa1, . . . ).

Spray compositions and particularly anhydrous aerosol compositions containing particulate antiperspirant actives exhibit a tendency for nozzle blockage, impeding discharge of the contents when a polyol humectant, such as glycerol, is blended into its base composition. The problem is overcome or at least ameliorated by preparation of a base composition, suitable for employment in conjunction with a propellant, that contains a low molecular weight (liquid) polyethylene glycol (PEG) as humectant, and particularly a PEG of molecular weight 150 to 500.

The present invention relates to methods and compositions comprising benzoquinones such as Duroquinone, for the use of treating, regulating or preventing a skin condition characterized by oxidative stress or a degenerative process. Methods of preventing, lightening or reducing the appearance of visible and / or tactile discontinuities of the skin resulting from skin pigmentation or skin aging are also disclosed.

A system for direct injection of selected thermal-infrared (IR) wavelength radiation or energy into articles for a wide range of processing purposes is provided. These purposes may include heating, raising or maintaining the temperature of articles, or stimulating a target item in a range of different industrial, medical, consumer, or commercial circumstances. The system is especially applicable to operations that require or benefit from the ability to irradiate at specifically selected wavelengths or to pulse or inject the radiation. The system is particularly advantageous when functioning at higher speeds and in a non-contact environment with the target.

Disclosed is a multi-beneficial topical skin care composition, and methods for its use, that can hydrate skin, increase the firmness of skin, reduce the appearance of fine lines or wrinkles on skin, and reduce the appearance of age spots on skin. The composition can include a combination of skin active ingredients comprising euterpe oleracea fruit extract, punica granatum sterols, caprooyl tetrapeptide-3, tocopherol or tocopherol acetate, and niacinamide, a combination of skin moisturizing agents comprising glycerin and butyrospermum parkii, a photo stable combination of sunscreen agents providing the composition with a sun protection factor (SPF) of at least about 15, and a dermatologically acceptable vehicle which imparts a non-greasy feel when applied to skin.

A method and apparatus for continuously applying labels to containers, and a container including a label on a surface thereof which has been applied thereto by the method and / or apparatus. An activating solution is sprayed by a sprayer onto a label pallet or directly onto a surface of a label containing an activatable coating or layer thereon. The activating solution activates the activatable coating or layer. The label is adhered to a container by placing the activated coating or layer of the label in contact with a surface of the container. The sprayer may deliver the activating solution to a surface of a label pallet or label with an even wet-out.

Methods and compositions for improving skin quality are disclosed. The methods include applying a solution of about 20-30% pre-wetting agent, such as hyaluronic acid, to a skin surface with concurrent dermabrasion treatment. These methods lead to significant improvement in the treatment of skin aging. Compositions for improving skin quality are also disclosed. These compositions comprise a pre-wetting agent and an abrasive agent.

Disclosed are compositions and corresponding methods of their use that include extracts from Loropetalum chinensis, Camptotheca acuminate, Lonicera maackii, Washingtonia filifera, Artemisia parviflora, Glochidion lanceolaris, Polygonum hydropiper, Populus davidiana, Tsoongiodendron odorum, Trema angustifolia, Ficus tikoua, Pistacia chinensis, Zizyphus mauritiana, Garuga forrestii, Michelia figo, Sabina chinensis, Cuphea balsamona, Setaria palmifolia, Polygonum lapathifolium, Machilus longipedicellata, Geranium nepalense, Ipomoea obscura, Cedrus deodara, Quercus aliena, Carqueja, Condurango, Catuaba, Carex baccans, Chrysalidocarpus lutescens, Gnaphalium pensylvanicum, Celtis sinensis, Cassia siamea, Catalpa yunnanesis, Potamogenton perforliatus, Cinnamomum japonicum, or any combination thereof.

A vehicular headlamp includes a lamp body having an opening, a first reflector disposed within the lamp body, a lens, and a second reflector. The second reflector serves as an extension reflector to cover a gap between the opening of the lamp body and the first reflector. The lens and the second reflector are joined together at an edge portion thereof by laser welding. The second reflector has a leg portion on a back surface thereof. An edge portion of the opening has a groove to receive the leg portion, and seal material having a predetermined adhesibility, which can be pulled off, is injected into the groove. The second reflector joined to the lens is mounted on an edge of the opening of the lamp body via the seal material.

A skin care formulation is provided, the formulation comprises dehydrated whole egg, at least one emollient substance and at least one humectant substance and the dehydrated whole egg is hydrated during the manufacturing process.

The invention provides a carrier device for a thermal transfer medium comprising a spool for winding and supporting a thermal transfer sheet or a thermal transfer receiving sheet, wherein a mark containing a coloring material which absorbs an electromagnetic wave of a predetermined wavelength λ1 and emitting an electromagnetic wave of a wavelength λ2 different from the wavelength λ1 is provided on a region in a surface of the carrier device capable of being irradiated with an electromagnetic wave. The invention provides a discrimination method and a printer each of which utilizes such a carrier device capable of executing at least one process among the kind identification, the fake goods determination and the use amount calculation for the thermal transfer sheet or the thermal transfer receiving sheet based on a detection of the mark.

Additives comprising dispersed silica nanoparticles are disclosed. The silica nanoparticles are dispersed in an aminoplast, such as a modified aminoplast formed from the reaction between an aminoplast, a modifying component, and optionally a siloxane. The resulting additives can be added to coating compositions to provide improved mar and / or scratch resistance.

An adaptive contrast enhancement method and device provide video signal contrast enhancement with reduced noise amplification. The video signal has a plurality of temporally ordered digital pictures, each one of the digital pictures represented by a set of samples, wherein each one of the samples has a gradation level. A contrast enhancement transform is constructed for enhancing the contrast of the video signal, and transform ratios are computed based on the contrast enhancement transform. Then the smoothed transform ratios are then applied to a set of samples representing a digital picture to enhance contrast of the digital picture with reduced noise amplification.

A circuit for display correction includes a memory which stores first data indicative of size and position of a rectangular region on a display screen and second data indicative of gray level changes in a surrounding region around the rectangular region in an isometric manner with respect to a horizontal direction and a vertical direction, and an image processing unit which adjusts gray levels of image data in response to the first data and the second data stored in the memory.

A cosmetic composition for reducing the appearance of lines, wrinkles and the size of pores in the skin is provided. The composition comprises a silica component, a silicon resin-coated elastomeric core component, and a cosmetic patch component, comprising algin / serine / atelocollagen, in a cosmetically acceptable aqueous vehicle.