843 results about "Vitamin C" patented technology

The invention discloses an oligopeptide from undaria pinnatifida and application thereof. The amino acid sequence of the oligopeptide is YRKD, and the molecular weight is 580.63 g / mol. The polypeptide is identified from undaria pinnatifida through a high performance liquid chromatography technology for the first time, and an unreported oligopeptide capable of inhibiting tyrosinase and cooperating with vitamin C to synergistically inhibit tyrosinase is screened out. The oligopeptide derived from undaria pinnatifida is synthesized by a solid phase method, has the characteristics of safety, no toxicity, good water solubility and good stability, and is combined with vitamin C to generate a synergistic effect and synergistically increase the inhibition effect on tyrosinase, so that the oligopeptide can achieve a better tyrosinase inhibition effect at a lower and more stable concentration; the use concentration of the oligopeptide can be greatly reduced, the stability is enhanced, and the oligopeptide can be widely applied to preparation of cosmetics, medicines, health-care products or food additives, and has important economic value and social significance.

The invention relates to a high-water-solubility denitroflavin covalent complex as well as a preparation method and application thereof, and belongs to the technical field of organic synthesis and medicinal chemistry. Comprising the following steps: (1) firstly, carrying out bromination reaction on 3-methyl-10-ethyl denitroflavin, so as to obtain 3-methyl-10-(1-bromoethyl) denitroflavin; and (2) coupling the 3-methyl-10-(1-bromoethyl) denitroflavin with vitamin C, so as to obtain the high-water-solubility denitroflavin covalent complex. According to the present invention, the prepared highly water-soluble denitrificin covalent complex has the two-phase solubility of the organic solvent and the water, such that the water solubility of the 3-methyl-10-ethyl-denitrificin is substantially enhanced, and the application range of the denitrificin is expanded. And meanwhile, the denitrified flavin covalent compound also has good antioxidant activity, and the antioxidant duration can be prolonged.

The invention discloses a drug-loaded polygonatum kingianum extracellular vesicle, a preparation method and an application of the drug-loaded polygonatum kingianum extracellular vesicle in preparation of an anti-photoaging product, and aims to provide a drug-loaded polygonatum kingianum extracellular vesicle which has relatively high encapsulation efficiency and drug loading rate and good stability and biocompatibility, can effectively treat skin UVB inflammation, solves the problem that a drug is insoluble in water, improves the curative effect, and can be used for preparing an anti-photoaging product and a preparation method of the drug-loaded polygonatum kingianum extracellular vesicle. According to the technical scheme, the drug-loaded polygonatum kingianum extracellular vesicles comprise the polygonatum kingianum extracellular vesicles and drug active components loaded in the polygonatum kingianum extracellular vesicles, and the drug-loaded polygonatum kingianum extracellular vesicles comprise the drug-loaded polygonatum kingianum extracellular vesicles and the drug active components loaded in the drug-loaded polygonatum kingianum extracellular vesicles. The pharmaceutical active component is at least one of resveratrol, glutathione, astaxanthin and vitamin C. The invention further discloses a preparation method of the pharmaceutical composition. The invention belongs to the technical field of biological medicine.

Various benefits to intestinal health are made by delivery of an active agent to the colon of an animal, including a human. Active ingredients include of riboflavin, vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, folic acid, β-carotene, vitamin B1, niacin, vitamin B5, vitamin B6, biotin, vitamin B12, omega-3 fatty acids and combinations thereof. Benefits include increased concentration of at least one short-chain fatty acid its salt thereof in the intestine, increased microbiome diversity in the intestine, increased beneficial bacteria in the intestine, increased the butyrate synthesis pathway in the intestine, improved barrier function of the intestine, reduced redox potential of the gut, reduced amount of gas produced in the intestine; and stimulation of intestinal immune responses.

Various benefits to intestinal health are made by delivery of an active agent to the colon of an animal, including a human. Active ingredients include of riboflavin, vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, folic acid, β-carotene, vitamin B1, niacin, vitamin B5, vitamin B6, biotin, vitamin B12, omega-3 fatty acids and combinations thereof. Benefits include increased concentration of at least one short-chain fatty acid its salt thereof in the intestine, increased microbiome diversity in the intestine, increased beneficial bacteria in the intestine, increased the butyrate synthesis pathway in the intestine, improved barrier function of the intestine, reduced redox potential of the gut, reduced amount of gas produced in the intestine; and stimulation of intestinal immune responses.

The present invention relates to vitamins for use in improving gut health in animals and humans. In particular, it was found that, upon delivery to the large intestine, vitamin B2, vitamin C, and vitamin D can be used for increasing the abundance of the beneficial bacteria Bifidobacterium animalis ssp. lactis in the intestinal tract.

The invention discloses ginseng and ganoderma lucidum compound polysaccharide liquid and a preparation method thereof in the technical field of functional food or biological medicine materials, and aims to improve the water solubility, bioavailability and functional activity of ginseng and ganoderma lucidum polysaccharide. Through a chemical-enzyme synergistic modification technology, two brand-new double-modified polysaccharides, namely carboxymethyl-sulfated double-modified ginseng polysaccharides and hydroxypropyl-phosphorylated ganoderma lucidum polysaccharides, are prepared. The two modified polysaccharides are mixed with deionized water, glycerin, sodium alginate and vitamin C according to a specific ratio, and a clarified and stable compound polysaccharide solution is prepared through the processes of ultrasonic dissolution, stirring, homogenization and the like. The polysaccharide solution breaks through the limitation of poor water solubility of natural polysaccharide, the water solubility is remarkably improved, the bioavailability is enhanced, the polysaccharide solution has the functions of immunoregulation, oxidation resistance and the like, the stability is good after the polysaccharide solution is placed at normal temperature after a stabilizer is added, and the polysaccharide solution is suitable for the field of functional food or biological medicine.

To provide a composition for hair capable of improving the volume of hair while suppressing the entanglement of hair, and to provide a hair treatment method using the composition for hair.SOLUTION: This composition for the hair is obtained by formulating (A) an amino acid-based cationic surface active agent with (B) one or more kinds selected from pantothenic acids, vitamin C or its salts, vitamin B3 or its salts and vitamin B6 or its salts. The hair treatment method uses the composition for hair.SELECTED DRAWING: None

The invention provides a gamma delta T cell culture method and a culture medium, and belongs to the technical field of T cell culture. Modified nanoparticles, zoledronic acid, vitamin C and glutamine are added into a 1640 culture solution, the concentration of the modified nanoparticles ranges from 0.5 g / L to 1 g / L, the concentration of the zoledronic acid ranges from 0.5 mu mol / L to 1.5 mu mol / L, the concentration of the vitamin C ranges from 200 mu mol / L to 500 mu mol / L, and the concentration of the glutamine ranges from 0.1 mmol / L to 0.2 mmol / L. The prepared culture medium can efficiently stimulate amplification of the gamma delta T cells and improve the killing activity of the gamma delta T cells, meanwhile, the survival rate of the gamma delta T cells is also improved, and meanwhile, the culture method of the gamma delta T cells is simple, low in cost and wide in application prospect.

The invention discloses a preparation method of olmacycline tosylate for injection, belongs to the technical field of pharmaceutical preparations, and provides a special preparation and a preparation method of the olmacycline tosylate for injection in order to solve the problems that the olmacycline tosylate for injection is prone to epimerization and oxidative degradation and the room temperature stabilization time is short after redissolution. According to the preparation, omagazines tosylate is used as a main component and matched with glycerol, vitamin C, thioglycerol, sodium acetate and water for injection, and the pH is adjusted to a proper range through hydrochloric acid or sodium hydroxide. According to the method, by means of the synergistic effect of glycerin and vitamin C, glycerin fixes medicine molecules and protects vitamin C, vitamin C removes oxidation inducements, and thioglycerin is matched to assist in inhibiting degradation, so that the medicine stability is greatly improved, the redissolved liquid medicine can be stabilized at 25 DEG C for 72 hours, the total impurities are controlled at a low level, and the clinical actual requirements are met.

The invention relates to a whitening and anti-aging composition which is characterized by comprising a solvent, a vitamin C derivative and an active agent, and the vitamin C derivative comprises 3-o-ethyl ascorbic acid, ascorbyl glucoside, magnesium ascorbyl phosphate, sodium ascorbyl phosphate and ascorbic acid polypeptide. By the adoption of the technical scheme, the whitening and anti-aging composition and the cosmetic containing the composition are high in stability, good in transdermal absorbability, lasting in effect, mild and capable of whitening skin and resisting aging in a synergistic mode.

The utility model provides a high performance liquid chromatograph for detecting the concentration of vitamin C in human serum. Comprising a degasser, a detector arranged above the degasser, an automatic sample injector arranged above the detector, a solvent frame arranged above the automatic sample injector, a column oven arranged on the automatic sample injector, a side door hinged to the outer side of the degasser, a valve body fixedly installed on the inner side of the degasser and a valve rod installed in the valve body. And an exhaust driving mechanism mounted on the valve body is fixedly mounted on the inner side of the degasser. According to the high performance liquid chromatograph for detecting the human serum vitamin C concentration, a two-way lead screw is automatically matched with thread transmission to drive a first clamping plate and a second clamping plate to move reversely, and then a solvent bottle located on the inner side of an avoiding hole is clamped and fixed through an anti-skid pad; the vibration generated when the high performance liquid chromatograph is used cannot cause the shaking of the solvent bottle, so that the high performance liquid chromatograph can well limit the solvent bottle.

The invention provides a teak camel moth artificial feeding feed and a teak camel moth artificial feeding method, the feed comprises the following components by weight: 8% of wheat germ powder, 4% of soybean meal, 4% of yeast powder, 2% of casein, 2% of sucrose, 1.8% of agar powder, 1.5% of cellulose, 0.8% of Webster salt, 0.6% of vitamin C, 0.2% of sorbic acid, 0.3% of methyl p-hydroxybenzoate, 0.1% of cholesterol, 0.1% of choline chloride, 0.05% of inositol, 0.01% of folic acid, and the balance of water. And the balance of deionized water. The invention further provides an artificial feeding method of teak camelmoths, and the artificial feeding method comprises the steps of 1, adult mating and egg laying, 2, egg disinfection and incubation and 3, larva rearing. The feed does not contain host material teak leaves, and full-artificial continuous large-scale feeding of the teak camelmoths can be achieved.

The invention provides a fruit juice fermentation inoculant, fermented guava juice and a preparation method, and belongs to the technical field of fermented beverages. The invention provides a compound fermentation inoculant capable of fermenting fruit juice, the compound fermentation inoculant is composed of lactobacillus plantarum and lactobacillus fermentum, the fermentation inoculant is applied to fermentation of guava fruit juice, beta-glucosidase secreted in the fermentation process can hydrolyze combined polyphenol substances in guavas, and then the guava fruit juice is fermented. The antioxidant is converted into high-activity antioxidants such as quercetin and gallic acid in a free state, so that the content of free phenol is increased by about 2 times, and the scavenging rate of DPPH free radicals is increased by more than 40%. The fermentation is carried out in an oxygen-free environment, the retention rate of vitamin C can reach 80% or above, the low pH value at the fermentation end point and organic acid jointly inhibit pathogenic microorganisms, and the product stability is guaranteed. Therefore, the guava juice prepared from the compound fermentation inoculant maximally releases the natural nutritional potential of guavas.

The invention discloses an astragaloside synergistic type composition as well as a preparation method and application of the astragaloside synergistic type composition. Comprising the following components: 8 to 16 parts of astragaloside, 20 to 40 parts of a honeysuckle flower extract, 10 to 20 parts of L-carnitine, 0.1 to 0.5 part of selenium yeast, 3 to 8 parts of diammonium glycyrrhizinate, 5 to 15 parts of taurine, 8 to 20 parts of a fructus forsythiae extract, 2 to 7 parts of vitamin E, 12 to 32 parts of hydroxypropyl-beta-cyclodextrin, 2 to 10.5 parts of maltodextrin, 1 to 7 parts of Arabic gum, 10 to 20 parts of lactose, 1 to 3 parts of zinc gluconate and 2 to 5 parts of magnesium stearate. 1-3 parts of vitamin C, 1-5 parts of xanthan gum and 1-3 parts of lecithin. The composition has a wide application prospect in preparation of veterinary drugs or veterinary food additives.

The invention relates to the technical field of pig feeds, and particularly discloses a special compound feed for weaning sows, the feed comprises a functional additive, the functional additive comprises the following raw materials in parts by weight: 1-3 parts of a plant extract compound, 2-5 parts of conjugated linoleic acid, 0.0003-0.0005 part of selenomethionine, 0.15-0.35 part of vitamin E, and 0.15-0.3 part of vitamin C; the plant extract compound is prepared from the following components: astragalus polysaccharide, icariin, epigallocatechin gallate and a carrier, and the mass ratio of the astragalus polysaccharide to the icariin to the epigallocatechin gallate is 1 to (1 to 4) to (0.2 to 0.8). The special compound feed for the weaned sows is used for feeding the weaned sows through a scientific and reasonable formula, can promote follicular development of the sows after weaning, improve the oestrus rate and reduce the proportion of non-oestrus sows, and can solve the problem of slow ovarian function recovery of the sows in summer high-temperature seasons.

The invention discloses a preparation method of a micron-sized cell-matrix co-polymer biological material. The preparation method comprises the following steps: firstly, inducing SHED cells in an ultra-low adsorption plate by using an alpha-MEM culture medium containing serum, GlutaMAXI, vitamin C and the like to form micron-sized spheres (SHED spheres); secondly, taking human dentin, and carrying out mechanical crushing, EDTA (Ethylene Diamine Tetraacetic Acid) demineralization, grinding and sterilization to prepare 1-100 microns of dentin matrix particles (DDMPs); and finally, by taking the GelMA hydrogel as a carrier, entrapping SHED spphere and DDMPs, and carrying out 405nm photo-crosslinking for 30 seconds to form the hydrogel. The co-polymer can significantly promote angiogenesis and osteogenesis coupling regeneration in a bone defect model, and is suitable for oral cavity and cranio-maxillofacial bone repair.

The invention relates to the technical field of soda wine preparation, in particular to a method and extraction equipment for preparing roselle soda wine from roselle extract.The method comprises the steps that dried roselle is subjected to low-temperature crushing and then extracted with an alcohol-water solution with the temperature controlled in stages, and a crude extracting solution is obtained; vitamin C and sodium citrate are compounded and stabilized, clarification and filtration are carried out, and a roselle extracting solution with stable color and flavor is obtained; and then scientifically blending with brandy base liquor, vodka, high fructose corn syrup, prebiotic syrup and other ingredients, finally carbonating with 0.5 volume of carbon dioxide at low temperature, and carrying out cold filling at the temperature of less than or equal to 4 DEG C to obtain a finished product. The problems that the extraction efficiency of natural flower raw materials is low, flavor and functional components are difficult to retain, and the fusion stability of an extract and a soda wine system is poor are effectively solved, and the comprehensive quality improvement that the product is outstanding in natural flavor, stable in color and luster, fine and lasting in bubble, healthy in function and good in drinking suitability is achieved.

This invention discloses a natural plant extract anti-gout product, its preparation method, and its application. The natural plant extract anti-gout product comprises the following raw material components in parts by weight: acerola cherry powder: 10-30 parts, bellflower powder: 10-30 parts, celery seed powder: 10-30 parts, peppermint leaf extract: 1-10 parts, and vitamin C: 3-15 parts. The peppermint leaf extract is concentrated at a ratio of 10:1 to 20:1 and prepared using a low-temperature extraction process. Its efficacy is clear and comprehensive: breaking through the limitations of existing single-component supplements, it constructs a three-dimensional efficacy system of "uric acid regulation - anti-inflammatory and analgesic - blood pressure auxiliary regulation." The components work synergistically to quickly relieve acute gout pain, balance blood uric acid levels in the long term, and assist in regulating blood pressure, meeting the dual needs of people with gout and hypertension. This solves the problems of limited efficacy and insufficient consideration of comorbidities in existing technologies.

The invention discloses a preparation method of a crocodile polypeptide extract and a beverage, and relates to the technical field of polypeptide extraction and beverage preparation, and the preparation method comprises the following steps: pretreatment of crocodile skin; denaturation treatment: adding a NaHCO3 buffer solution, and treating under a microwave condition; performing ultrasonic pretreatment; carrying out enzymolysis reaction, namely sequentially carrying out primary enzymolysis of alkaline protease and secondary enzymolysis of compounding trypsin and neutral protease; adding composite colloid after enzyme deactivation treatment, wherein the composite colloid comprises flaxseed gum and xanthan gum; centrifuging to take supernate, and carrying out fractional separation through ultrafiltration membranes with the molecular weight cut-off of 500Da and 1000Da; and concentrating and drying to obtain polypeptide powder. According to the method, the polypeptide yield, the beverage stability and the oral bioavailability are improved; finally, the obtained polypeptide is scientifically matched with hyaluronic acid and vitamin C to prepare the beautifying beverage with the effects of remarkably improving skin stains and fine wrinkles and brightening the skin color, and the breakthrough of high-value utilization of crocodile skin resources and product function integration is realized.

The invention relates to the technical field of food processing, and particularly discloses a heart and cerebral vessel health care composition with thrombolytic and antithrombotic functions and a preparation method thereof. The composition consists of the following raw materials: sorbitol, red yeast rice, freeze-dried natto powder, earthworm protein peptide, vitamin C, American ginseng peptide, magnesium stearate, an angelica sinensis extract, rice bran fatty alkanol, vitamin B1, vitamin B2, a turmeric extract and a compound coloring agent. The preparation method comprises the following steps: mixing the raw materials except magnesium stearate in a double-cone mixer; magnesium stearate is added for continuous mixing, and a hollow capsule shell is filled with the mixed material. The composition disclosed by the invention forms a multi-dimensional synergistic system for smoothing blood vessels, purifying blood and improving blood flow, the defect of single effect of an existing product is overcome, the health-care effect of heart and cerebral vessels is remarkably improved, and the effect is stable and controllable; in addition, the preparation method has the advantages of being simple and controllable in process and suitable for industrial production.

1. Name of the product in this design: Packaging bag (Kangxue Astragalus Vitamin C Anti-wrinkle Crystal Mask). 2. Purpose of this design: Packaging bag for cosmetics. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key features: the front view.

The present invention discloses a low GI blackcurrant jam and a preparation method thereof, and relates to the technical field of food processing, the low GI blackcurrant jam comprises the following components by mass: 50-70 parts of blackcurrant pulp, 15-35 parts of a composite sugar source, 0.3-1.5 parts of a compound thickener, 0.1-0.7 part of an acidity regulator, and 5-15 parts of water; the composite sugar source consists of psicose, inulin and resistant dextrin; the compound thickening agent is prepared from apple gum, konjac gum and xanthan gum; the preparation process comprises the following steps: step-by-step sugar melting under a mild condition, colloid pre-dispersing gel melting, fruit pulp mixing, pasteurization, acid regulation and homogenization, sterilization after filling and the like. Through the cooperation of a formula system and a whole-process mild temperature control process, a stable three-dimensional gel network is constructed while the low GI value and the high vitamin C retention rate of the product are achieved, water bleeding and layering are effectively prevented, and therefore the jam product with the healthy property and the excellent texture is obtained.

1. Name of the product in this design: Packaging Box (VC Five-Fold Vitamin C Soothing and Cleansing Makeup Remover). 2. Purpose of this design: a packaging box for holding cosmetics. 3. The key design elements of this product are the combination of shape, pattern, and color. 4. The image or photograph that best illustrates the key design points: Design 1 3D view. 5. The design for which protection is sought includes color. 6. Design 1 is designated as the basic design.

The application provides a compound microbial fertilizer, a preparation method and application thereof. The compound microbial fertilizer comprises the following components in parts by weight: 10-30 parts of a compound microbial agent, 20-50 parts of an agent carrier, 30-50 parts of a compound fertilizer slow-release agent and 10-30 parts of modified urea aldehyde. The compound microbial fertilizer prepared by the application can be applied to growth tests of tomatoes, and higher yield, stem thickness growth value, vitamin C content and sugar acid ratio can be obtained. The compound microbial fertilizer has long-term effect, can release phosphorus, nitrogen and potassium and the like, has the effects of moisturizing and loosening soil, can increase the yield and quality of tomato fruits, promote the robustness of roots and stems and improve the eating taste.

The present invention provides a homocysteine-reducing composition that rapidly lowers blood homocysteine ​​levels to an appropriate level without causing any concerns about side effects. [Solution] A composition for reducing homocysteine ​​levels, comprising one or more B vitamins selected from vitamin B6, vitamin B12, and folic acid, and β-NMN as active ingredients. The β-NMN content is in the range of 22.32% to 89.29% by weight. Vitamin C and vitamin B2 may also be added.

This application relates to a graphene heat dissipation film and its preparation method. The preparation method of the graphene heat dissipation film includes the following steps: preparing a mixed slurry containing graphene oxide and a defect repair agent; performing a film-forming treatment on the mixed slurry to obtain a first film; performing carbonization, graphitization, and calendering treatment on the first film to obtain a second film; forming a radiation heat dissipation layer on the second film to obtain the graphene heat dissipation film; wherein, the graphene oxide includes at least two of first graphene oxide, second graphene oxide, and third graphene oxide; the lateral dimension of the first graphene oxide is larger than the lateral dimension of the second graphene oxide; the lateral dimension of the second graphene oxide is larger than the lateral dimension of the third graphene oxide; the defect repair agent includes at least one of glucose, citric acid, citrate, and vitamin C. This graphene heat dissipation film has the advantages of low structural defects, high production yield, diverse heat dissipation mechanisms, and excellent heat dissipation performance.

The invention discloses a food therapy height increasing method. The food therapy height increasing method comprises the following raw materials: enzymolysis bone calcium, oyster peptide, vitamin C, beta-carotene and hemin chloride. According to the present invention, the components such as the enzymolysis bone calcium, the oyster peptide, the vitamin C, the beta-carotene, the heme chloride and the like, which are beneficial to bone repair and bone growth and development, are extracted so as to meet the bone growth requirements of teenagers and children; the raw materials are processed and prepared into powder, all the components are prepared into the solid beverage in a mixing mode, and the solid beverage can be taken by adding sugar or honey or other flavors into water when being eaten. In conclusion, the solid beverage is suitable for teenagers and children to eat, different from a traditional food therapy mode, various growth promoting requirements are met, cooking is not needed, and the solid beverage can be taken after being mixed with water and is convenient to eat.

The invention discloses a rabdosia rubescens and roxburgh rose stock solution (puree) and honey beverage and a preparation method thereof, and belongs to the technical field of functional beverages. The beverage is prepared from the following raw materials in parts by weight: 20-50 parts of a rabdosia rubescens extracting solution, 80-150 parts of a roxburgh rose stock solution (primary pulp), 10-30 parts of honey and 50-200 parts of water. The preparation method comprises the following steps: decocting and extracting rabdosia rubescens for a short time, mixing with a roxburgh rose stock solution, adding honey and water, blending, standing, filtering, filling, sterilizing and the like. The beverage gives full play to the synergistic effects of the rabdosia rubescens for clearing away heat and toxic materials, the roxburgh rose for resisting oxidation due to high-dimensional C and the honey for moistening lung to arrest cough, meanwhile, taste coordination is realized through scientific proportioning, the problems of bitterness of the rabdosia rubescens and over-acidity of the roxburgh rose are solved, and the beverage has the advantages of synergistic function, unique taste, simple process, good stability and the like, and is suitable for industrial production.

The invention relates to a method for fermenting fermented soya beans by rosa roxburghii tratt fruits, soybeans and black beans. The fermentation comprises the following steps: pretreating raw materials, fermenting to prepare fermented soya bean koji, post-fermenting and drying. 3-5 wt% of roxburgh rose juice and 3-5 wt% of roxburgh rose pulp residues are added in the post-fermentation step, the roxburgh rose pulp residues can enrich the taste of the fermented soya bean finished product, roxburgh roses contain rich vitamin C and polyphenol substances and are natural antioxidants, and bad flavor generated by oxidative rancidity of fatty acid in the post-fermentation and storage process of the fermented soya beans is prevented; meanwhile, the soybeans are rich in unsaturated fatty acid, the healthy lipid components are protected from being damaged through the antioxidant effect of the roxburgh rose, the retained unsaturated fatty acid can serve as a precursor to help saccharomycetes to generate more ester aroma substances, the antioxidant effect of the roxburgh rose and microorganisms in the fermented soya beans achieve the synergistic effect, and the effect of improving the immunity of the fermented soya beans is achieved. The flavor is indirectly enhanced, the original taste is not influenced, and the stability and the nutritional value of the fermented soya beans are also improved.