9 results about "Preservative free" patented technology

Multi-dose preservative-free ocular fluid delivery devices are provided. The fluid delivery device includes a fluid dispensing system and a fluid package for storing a liquid therein and supplying said liquid to the dispensing system. The dispensing system comprises an elongated chamber which includes a check valve which defines a frontal closure to the chamber. The valve is normally closed and hermetically seals the chamber. The dispenser includes a vibration motor that induces oscillations to the chamber and to the fluid within. The oscillations of the chamber impart momentum to the fluid stored in the chamber which in turn imparts force that cyclically opens the valve to dispense streams or liquid droplets. Fluid is dispensed only when the motor oscillates while otherwise the valve is hermetically closed. The fluid package can be made collapsible to remove the need to vent it.

Multi-dose preservative-free ocular fluid delivery devices are provided. The fluid delivery device includes a fluid dispensing system and a fluid package for storing a liquid in the fluid package and supplying the liquid to the dispensing system. The dispensing system includes an elongated chamber including a check valve defining an anterior closure of the chamber. The valve is normally closed and hermetically seals the chamber. The dispenser includes a vibrating motor that causes oscillation of the chamber and the fluid within the chamber. The oscillation of the chamber imparts momentum to the fluid stored in the chamber, which in turn imparts force to cyclically open the valve to dispense a stream or liquid droplets. Fluid is only dispensed when the motor is oscillating, otherwise the valve is hermetically closed.

The invention discloses moisturizing and anti-aging soft mask powder and a preparation and use method thereof, sodium alginate, calcium sulfate and hydroxypropyl methyl cellulose synergistically construct a stable film-forming system, and the stable film-forming system is compounded with an opuntia ficus-indica fruit extract, low-molecular sodium hyaluronate and panthenol to form a long-acting moisturizing network; meanwhile, multiple anti-aging active matters such as oligopeptide and roselle flower extract are integrated. The soft mask powder has the characteristics of rapid and smooth film formation, excellent moisturizing performance and remarkable anti-oxidation and anti-aging effects, does not contain preservatives, artificial pigments and spices, is safe and mild, and is suitable for professional nursing and daily anti-aging and moisturizing.

The invention relates to extremely mild, concentrated cleansing compositions to create personal care formulations. The mildness of composition towards the skin is due to the synergy of constituent members. More specifically, the compositions comprise of cocamidopropyl PG dimonium chloride phosphate, an alkyl polyglucoside, and sophorolipids to give the superlative performance in terms of foam and lather with extreme gentleness towards the stratum corneum, the uppermost layer of the skin. The concentrated, self-preserving, ultra-mild compositions of the present invention are particularly suitable for cleansing of sensitive skin (babies and sensitive body parts), irritated skin (medically compromised) and very dry skin (senior citizens). Also process for preparing such ultra-mild cleansing composition is provided.

The application discloses an auxiliary medical eye-care liquid with rehabilitation, health care, cleaning, moistening, nutrition and water base of snow water and a preparation method thereof. Traditional water-containing eye products such as eye lotion (eye drops) contain water ingredients, and the water ingredients are not obtained by adding natural snow water in December. The application adopts a mode of replacing the water ingredients in the original eye products such as eye lotion (eye drops) with natural snow water to realize the application. The natural snow water eye-care liquid of the application contains natural snow water and other ingredients in the original traditional products except the water ingredients. The preparation process is the same as that of the original eye products such as eye lotion (eye drops). The application has the advantages that the eye products such as eye lotion (eye drops) do not contain preservatives and have less deuterium elements.

This disclosure relates, in general, to ophthalmic compositions and multi-dose systems for topically applying the compositions to a surface, for example, the ocular surface. The multi-dose systems of this disclosure may include a multi-dose preservative-free (MDPF) eye drop bottle system and an ophthalmic composition having a therapeutic agent, a viscosity modifier having a concentration of about 0.01% w / v to about 5% w / v, and a surfactant having a concentration of about 0.005% w / v to about 7% w / v, wherein the composition is preservative-free.

The application provides a functional monomer shown in formula (I), a preparation method thereof, a gel prepared from the functional monomer, a gel dressing and application of the gel dressing. The application uses polyvinyl alcohol, polyglutamic acid and acrylic acid as gel raw materials, adds sodium chloride as an effective component, adds initiators and crosslinking agents, grafts a compound shown in formula (I) containing a disulfide bond, forms an interpenetrating gel network, and the prepared gel dressing can be quickly attached to the skin and can be easily and completely removed from the skin surface. The gel dressing solves the problem of poor patient compliance, and the gel dressing can be attached to the common warts when used, which is simple and convenient, does not contain preservatives, is completely non-toxic and non-side effect to the human body, and is safe and reliable. Experimental results show that the gel dressing provided by the application can be quickly attached to the skin and form stable adhesion, and can be easily and completely separated from the skin under the action of sodium bicarbonate and glutathione after the warts disappear.

The present invention relates to a spray device comprising a nozzle body (2) and a substantially flat membrane layer (6) suspended over a nozzle cavity (3) for generating microjets, especially for pharmaceutical applications, particularly preservative-free formulations. The nozzle body (2,8) contains an antimicrobial barrier, in particular a microvalve (23,24) between a fluid supply channel (9) and said cavity (3).

The present disclosure provides a composition comprising temozolomide or lenalidomide, a medium chain triglyceride (e.g., miglyol), silica, and a surfactant wherein the composition optionally comprises an antioxidant and / or a flavouring agent, and wherein the temozolomide composition is a non-aqueous, preservative-free suspension. Also provided are methods for treating cancer in a subject (e.g., a child or a subject with and / or with dysphagia).