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2839 results about "Human skin" patented technology

The human skin is the outer covering of the body and is the largest organ of the integumentary system. The skin has up to seven layers of ectodermal tissue and guards the underlying muscles, bones, ligaments and internal organs. Human skin is similar to most of the other mammals skin, and it is very similar to pig skin. Though nearly all human skin is covered with hair follicles, it can appear hairless. There are two general types of skin, hairy and glabrous skin (hairless). The adjective cutaneous literally means "of the skin" (from Latin cutis, skin).

Bone-conduction hearing-aid transducer having improved frequency response

A hearing-aid device and a method for transmitting sound through bone conduction are disclosed. The hearing-aid device comprises a piezoelectric-type actuator, housing and connector. The piezoelectric actuator is preferably a circular flextensional-type actuator mounted along its peripheral edge in a specifically designed circular structure of the housing. During operation, the bone-conduction transducer is placed against the mastoid area behind the ear of the patient. When the device is energized with an alternating electrical voltage, it flexes back and forth like a circular membrane sustained along its periphery and thus, vibrates as a consequence of the inverse piezoelectric effect. Due to the specific and unique designs proposed, these vibrations are directly transferred trough the human skin to the bone structure (the skull) and provide a means for the sound to be transmitted for patients with hearing malfunctions. The housing acts as a holder for the actuators, as a pre-stress application platform, and as a mass which tailors the frequency spectrum of the device. The apparatus exhibits a performance with a very flat response in the frequency spectrum 200 Hz to 10 kHz, which is a greater spectrum range than any other prior art devices disclosed for bone-conduction transduction which are typically limited to less than 4 kHz.
Owner:FACE INT

Intra-serum and intra-gel for modeling human skin tissue

The invention provides a class of samples that model the human body. This family of samples is based upon emulsions of oil in water with lecithin acting as the emulsifier. These solutions that have varying particle sizes may be spiked with basis set components (albumin, urea and glucose) to simulate skin tissues further. The family of samples is such that other organic compounds such as collagen, elastin, globulin and bilirubin may be added, as can salts such as Na+, K+ and Cl-. Layers of varying thickness with known index of refraction and particle size distributions may be generated using simple crosslinking reagents, such as collagen (gelatin). The resulting samples are flexible in each analyte's concentration and match the skin layers of the body in terms of the samples reduced scattering and absorption coefficients, mums and muma. This family of samples is provided for use in the medical field where lasers and spectroscopy based analyzers are used in treatment of the body. In particular, knowledge may be gained on net analyte signal, photon depth of penetration, photon radial diffusion, photon interaction between tissue layers, photon density (all as a function of frequency) and on instrument parameter specifications such as resolution and required dynamic range (A/D bits required). In particular, applications to delineate such parameters have been developed for the application of noninvasive glucose determination in the near-IR region from 700 to 2500 nm with an emphasis on the region 1000 to 2500 nm (10,000 to 4,000 cm-1).
Owner:GLT ACQUISITION

Method of isolating epithelial cells, method of preconditioning cells, and methods of preparing bioartificial skin and dermis with the epithelial cells or the preconditioned cells

A method of isolating epithelial cells from a human skin tissue or internal organ tissue using trypsin and ethylenediamine tetraacetic acid (EDTA) simultaneously with the application of magnetic stirring, a method of preconditioning isolated biological cells by the application of physical stimulus, i.e., strain, are provided. Epithelial cells can be isolated by the method with increased yield, colony forming efficiency (CFE), and colony size. Also, the increased percentage of stem cells in isolated cells is advantageous in therapeutic tissue implantation by autologous or allogeneic transplantation. In skin cells preconditioned by the application of strain, cell division is facilitated, and the secretion of extracellular matrix components and growth factors and the activity of matrix metalloproteinases (MMPs) are improved. When preconditioned cells are implanted by autologous or allogeneic transplantation to heal a damaged tissue, the improved cell adhesion, mobility, and viability provides a biological adjustment effect against a variety of stresses or physical stimuli which the cells would undergo after implantation, with improved capability of integration into host tissue, thereby markedly improving the probability of success in skin grafting.
Owner:KOREA INST OF RADIOLOGICAL & MEDICAL SCI

Biocompatible cemented carbide articles and methods of making the same

InactiveUS20070082229A1Eliminate and minimize toxic effectReduce concentrationSurgeryJewelleryBiocompatibility TestingAlloy
This invention relates to cemented carbide articles that are characterized by substantially improved biocompatibility with human skin, tissue, organs, etc., compared with articles made from conventional cemented carbides. The essential feature of these improved biocompatible cemented carbide articles is a binder-depleted zone at and near the exposed surfaces of the articles. By depleting the binder (which mainly consists of Co and / or Ni, as well as their alloys) at and near the surface, the toxic effects of Co and Ni (known carcinogens), as well as the allergic reactions that these metals can cause when in contact with human skin, are eliminated. By depleting the binder only at and near the surface, the bulk properties of the cemented carbide article are not compromised or altered in any manner. Applications of these binder-depleted cemented carbides could include articles that human skin may experience prolonged exposure to, for example, jewelry articles such as rings, bracelets, bangles, chains, necklaces, pendants, watches, watch cases, watch straps, etc. In addition, the cemented carbides of this invention may be used in applications where the article comes directly in contact with human skin, tissue, organs, etc. such as surgical and other medical instruments, razor blades, etc. Also, other applications could include knives, tools, dies, and other wear components that are used to process and handle, and hence, come into direct contact with materials meant for human consumption and / or ingestion. Examples of such materials include foodstuffs and pharmaceuticals.
Owner:MIRCHANDANI RAJINI P +1

Bone-conduction hearing-aid transducer having improved frequency response

A hearing-aid device and a method for transmitting sound through bone conduction are disclosed. The hearing-aid device comprises a piezoelectric-type actuator, housing and connector. The piezoelectric actuator is preferably a circular flextensional-type actuator mounted along its peripheral edge in a specifically designed circular structure of the housing. During operation, the bone-conduction transducer is placed against the mastoid area behind the ear of the patient. When the device is energized with an alternating electrical voltage, it flexes back and forth like a circular membrane sustained along its periphery and thus, vibrates as a consequence of the inverse piezoelectric effect. Due to the specific and unique designs proposed, these vibrations are directly transferred through the human skin to the bone structure (the skull) and provide a means for the sound to be transmitted for patients with hearing malfunctions. The housing acts as a holder for the actuators, as a pre-stress application platform, and as a mass which tailors the frequency spectrum of the device. The apparatus exhibits a performance with a very flat response in the frequency spectrum 200 Hz to 10 kHz, which is a greater spectrum range than any other prior art devices disclosed for bone-conduction transduction which are typically limited to less than 4 kHz.
Owner:FACE INT

Microphone and communication interface system

InactiveUS20050244020A1Avoid damaging the environmentHigh expiratoryMouthpiece/microphone attachmentsSpeech recognitionCultural practiceHuman body
The present invention eliminates the disadvantages of an analysis target used by a cellular phone and speech recognition, that is, a normal sound which is transmitted through the air and which is externally sampled through a microphone, and improves the disadvantages that noise may be mixed or occur in the target, that information may leak, and that corrections are difficult. The present invention also provides a personal portable information terminal realizing new portable terminal communications which do not require training and which conform to the cultural practice of human beings. In the present invention, no apparatus that obtains an analysis target is put off human body, and a normal sound is not an analysis target. A stethoscope-type microphone is installed on the surface of the human skin. Then, a vibration sound is sampled which is obtained when a non-audible murmur articulated in association with speech action (the motion of the mouth) not using the regular vibration of the vocal cords is transmitted through the flesh. A vibration sound obtained when a non-audible murmur amplified is transmitted through the flesh is similar to a whisper. The vibration sound can thus be heard and understood by human beings. Accordingly, the vibration sound can be used for a speech over the cellular phone as it is. Further, when the vibration sound obtained when the non-audible murmur is transmitted through the flesh is analyzed and converted into parameters, a kind of soundless recognition is realized. The present invention replaces the HMM model, conventionally used for speech recognition by an acoustic model created on the basis of a vibration sound obtained when a non-audible murmur is transmitted through the flesh. Therefore, the present invention provides a new method of inputting data to the personal portable information terminal.
Owner:NARA INSTITUTE OF SCIENCE AND TECHNOLOGY

Speckle reduction in optical coherence tomography by path length encoded angular compounding

Speckle, a factor reducing image quality in optical coherence tomography (“OCT”), can limit the ability to identify cellular structures that are important for the diagnosis of a variety of diseases. Exemplary embodiments of the present invention can facilitate an implementation of an angular compounding, angular compounding by path length encoding (“ACPE”) for reducing speckle in OCT images. By averaging images obtained at different incident angles, with each image encoded by path length, ACPE maintains high-speed image acquisition and implements minimal modifications to OCT probe optics. ACPE images obtained from tissue phantoms and human skin in vivo demonstrate a qualitative improvement over traditional OCT and an increased signal-to-noise ratio (“SNR”). Accordingly, exemplary embodiments of an apparatus probe catheter and method can be provided for irradiating a sample. In particular, an interferometer may forward forwarding an electromagnetic radiation. In addition, a sample arm may receive the electromagnetic radiation, and can include an arrangement which facilitates a production of at least two radiations from the electromagnetic radiation so as to irradiate the sample. Such exemplary arrangement can be configured to delay a first radiation of the at least two radiations with respect to a second radiation of the at least two radiations.
Owner:THE GENERAL HOSPITAL CORP
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